No definition available.
Chronic respiratory disease originating in the perinatal period
P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
81 |
4. Check minimum number of eventsNone |
81 |
5. Include endpointsNone |
81 |
6. Filter based on genotype QC (FinnGen only) |
81 |
Control definitions (FinnGen only)
- Control exclude
- P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P2
- Name in latin
- Morbus respiratorius chronicus origine perinatalis
Similar endpoints
↥List of similar endpoints to
Chronic respiratory disease originating in the perinatal period
based on the number of shared cases.
Similar with more cases:
- Respiratory and cardiovascular disorders specific to the perinatal period
- Certain conditions originating in the perinatal period
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2666 | 1099 | 1567 |
| Only index persons | 1532 | 618 | 914 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.03 | 0.04 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | - | 0.00 | 0.00 |
| Only index persons | 0.03 | 0.00 | 0.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 81 | 42 | 39 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 0.04 | 0.04 | 0.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 67
- Matched controls
- 671
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
7837.3
84.5
63
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
124.3
46.8
48
13
P07.2
ICD-10 Finland
Extreme immaturity
+∞
38.2
33
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
+∞
30.6
27
*
602
Kela drug reimbursment
Children's severe malnutrition
30.9
23.6
32
19
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
16.5
23.2
47
83
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
22.1
20
*
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
+∞
18.6
17
*
J45.1
ICD-10 Finland
Nonallergic asthma
12.7
18.0
37
59
WX722
NOMESCO Finland
PEEP
49.8
18.0
21
6
P07.3
ICD-10 Finland
Other preterm infants
22.6
16.5
24
16
R03BA02
ATC
budesonide; inhalant
10.1
15.4
36
69
F82
ICD-10 Finland
Specific developmental disorder of motor function
22.8
14.7
21
13
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
+∞
14.0
13
*
FDE00
NOMESCO Finland
Closure of patent ductus arteriosus
+∞
14.0
13
*
WX730
NOMESCO Finland
Conventional respirator
63.2
13.5
15
*
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
+∞
11.8
11
*
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
129.4
10.8
11
*
XG413
NOMESCO Finland
Spirometry with oscillometry
15.8
10.6
17
14
6BB16
NOMESCO Finland
NA
47.8
10.3
12
*
Z3229
NOMESCO Finland
Other healthcare associate professional
8.0
10.3
25
46
R4110
NOMESCO Finland
Physiotherapy
5.8
10.3
39
130
RK310
NOMESCO Finland
NA
+∞
9.6
9
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
10.1
9.5
19
25
J45.9
ICD-10 Finland
Asthma, unspecified
6.2
9.5
29
73
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
15.7
9.4
15
12
WX408
NOMESCO Finland
General anesthesy, balanced
5.2
9.3
42
163
P05.1
ICD-10 Finland
Small for gestational age
28.7
9.3
12
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.7
9.3
26
58
R03AC02
ATC
salbutamol; inhalant
6.0
9.1
55
289
WX704
NOMESCO Finland
Intubation
19.7
9.0
13
8
R03AK06
ATC
salmeterol and fluticasone; inhalant
7.6
8.6
21
38
ZXD05
NOMESCO Finland
Urgent procedure
5.2
8.4
31
95
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.0
8.3
25
60
WX725
NOMESCO Finland
Noninvasive ventilation
25.8
8.3
11
5
ZX114
NOMESCO Finland
Intramuscular
13.2
8.3
14
13
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.2
8.1
29
85
Z2446
NOMESCO Finland
Social worker
5.0
8.0
31
99
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
5.3
7.7
26
71
R03BA05
ATC
fluticasone; inhalant
4.5
7.7
36
136
RK320
NOMESCO Finland
NA
89.6
7.6
8
*
RK520
NOMESCO Finland
NA
89.6
7.6
8
*
XA800
NOMESCO Finland
Neuropsychological investigation
6.9
7.5
19
36
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.2
7.5
21
46
WX732
NOMESCO Finland
High frequency respirator
+∞
7.4
7
*
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
7.4
7
*
Z3226
NOMESCO Finland
Physiotherapist
4.4
7.4
35
133
ZX108
NOMESCO Finland
Inhalation
16.1
7.2
11
8
Z3231
NOMESCO Finland
Registered nurse
4.1
7.1
43
202
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
19.2
7.0
10
6
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
19.2
7.0
10
6
Z2221
NOMESCO Finland
Medical doctor
4.1
6.8
33
127
ZXD10
NOMESCO Finland
Scheduled procedure
4.0
6.8
40
180
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.5
6.6
17
33
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
76.9
6.5
7
*
ZXE00
NOMESCO Finland
One hour or less
3.9
6.5
41
192
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
9.2
6.5
13
17
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.3
6.4
17
34
WX882
NOMESCO Finland
High dependency care
5.0
6.4
22
60
RK312
NOMESCO Finland
NA
29.8
6.4
8
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.8
6.4
41
198
P29.31
ICD-10 Finland
Persistent fetal circulation
+∞
6.3
6
*
RK290
NOMESCO Finland
NA
+∞
6.3
6
*
ZXE10
NOMESCO Finland
More than one and less than three hours
3.9
6.3
34
140
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
11.7
6.3
11
11
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
7.1
6.3
15
26
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.7
6.3
14
22
Z2445
NOMESCO Finland
Psychologist
4.8
6.2
22
62
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
6.2
21
57
UGC02
NOMESCO Finland
Rigid bronchoscopy
17.0
6.1
9
6
Mortality – FinRegistry
↥Association
Association between endpoint P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: P16_CHRONIC_RESPI_DISEA_ORIGINA_PERINA_PERIOD – Chronic respiratory disease originating in the perinatal period
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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