info icon

Malignant neoplasm of breast, HER-negative

C3_BREAST_ERNEG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

  • not RX_ERPLUS
252741

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C50
  • Cause of death: ICD-9 174
  • Cause of death: ICD-8 174
  • Cancer registry: Topography ICD-O-3 C50
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes [23]

2 out of 7 registries used, show all original rules.

8774

4. Check minimum number of events

None

8774

5. Include endpoints

None

8774

6. Filter based on genotype QC (FinnGen only)

8469

Control definitions (FinnGen only)

Control conditions
not RX_ERPLUS

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 8469 8469 -
Unadjusted period prevalence (%) 3.33 3.33 -
Median age at first event (years) 58.37 58.37 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
8764
Matched controls
87584
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
263.7
323.0
427
17
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
310.5
323.0
737
26
WF003
NOMESCO Finland
Adjuvant radiotherapy
10.6
323.0
697
707
A04AA55
ATC
palonosetron, combinations; systemic
30.5
323.0
1135
424
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
98.7
323.0
1599
197
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
241.8
323.0
1064
50
PJA12
NOMESCO Finland
Sentinel node biopsy
140.2
323.0
4604
687
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
174.6
323.0
495
30
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
238.8
323.0
663
30
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
323.0
3909
17998
L03AA13
ATC
pegfilgrastim; parenteral
17.4
323.0
1047
676
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
41.8
323.0
445
112
ZX090
NOMESCO Finland
Other technic of radiotherapy
15.9
323.0
590
396
C50
ICD-10 Finland
Malignant neoplasm of breast
445.8
323.0
1171
30
XX1XN
NOMESCO Finland
Other isotope examination
307.0
323.0
463
16
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
910.8
323.0
434
5
115
Kela drug reimbursment
Breast cancer
5466.1
323.0
3295
9
L02BG04
ATC
letrozole; oral
28.2
323.0
742
286
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.1
323.0
2734
11145
X76
ICPC
Malignant neoplasm breast female
309.5
323.0
735
26
8500/3-C50.2
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-inner quadrant of breast
+∞
323.0
379
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
1183.5
323.0
450
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
166.5
323.0
591
38
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
52.9
323.0
773
160
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
263.4
323.0
474
19
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
323.0
1132
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
420.4
323.0
809
21
Z31.5
ICD-10 Finland
Genetic counselling
7.0
323.0
927
1446
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
20.9
323.0
2453
1601
NK6AN
NOMESCO Finland
Total body bone isotope imaging
37.4
323.0
462
130
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
323.0
453
*
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
197.7
323.0
659
36
N63
ICD-10 Finland
Unspecified lump in breast
6.1
323.0
1455
2762
TQW20
NOMESCO Finland
Tatoe
160.2
323.0
485
32
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
483.3
323.0
590
13
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
94.3
323.0
782
91
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
179.0
323.0
678
41
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
323.0
3519
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
20.2
323.0
1522
901
C50.99
ICD-10 Finland
Breast, unspecified
236.1
323.0
1508
77
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
299.6
323.0
2772
135
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
536.5
323.0
603
12
ZX080
NOMESCO Finland
Image guided radiotherapy
37.3
323.0
687
199
L03AA14
ATC
lipegfilgrastim; parenteral
18.4
323.0
545
315
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
28.2
323.0
815
317
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
338.6
323.0
739
24
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
29.7
323.0
1670
688
HA1AA
NOMESCO Finland
X-ray mammography
20.0
323.0
2893
2110
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
74.0
323.0
1672
278
H02AB02
ATC
dexamethasone; systemic
10.2
323.0
2382
3084
HAC20
NOMESCO Finland
Total mastectomy
397.2
323.0
2156
72
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
59.0
323.0
1231
242
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
692.8
323.0
933
15
XX3DW
NOMESCO Finland
Time consuming IT work
8.2
323.0
2118
3263
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
228.9
323.0
1610
86
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
392.2
323.0
3440
144
HAB99
NOMESCO Finland
Other partial excision of mammary gland
27.1
323.0
987
408
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
323.0
1249
*
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
111.0
323.0
473
45
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
78.4
323.0
1083
157
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
30.1
323.0
469
164
HAB40
NOMESCO Finland
Wedge excision of mammary gland
143.3
323.0
3240
357
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
4801.1
323.0
466
*
HA6BA
NOMESCO Finland
Breast tomosynthesis specimen
96.5
323.0
535
59
A03FA01
ATC
metoclopramide; systemic, rectal
4.0
323.0
3243
11272
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
206.5
323.0
1087
60
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
533.1
323.0
1868
44
A04AA02
ATC
granisetron; systemic, transdermal
9.3
323.0
1204
1470
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
19.1
323.0
1137
679
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
50.5
323.0
586
124
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
17.4
308.5
500
303
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
248.6
304.8
312
13
WX402
NOMESCO Finland
General anaesthesia
3.1
301.3
2005
7691
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
1513.7
297.2
288
*
L02BA01
ATC
tamoxifen; oral
88.3
281.4
315
37
HA1BG
NOMESCO Finland
MRI examination of mammary gland with high intensity magnet
68.7
280.8
325
49
WZC30
NOMESCO Finland
Teaching
3.3
280.0
1632
5662
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
325.3
278.1
281
9
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
6.3
277.3
790
1355
HAE99
NOMESCO Finland
Other reconstruction of breast
77.8
276.9
315
42
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
319.1
272.9
276
9
A04AD12
ATC
aprepitant; systemic
17.3
266.4
432
261
8500/3-C50.5
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-outer quadrant of breast
+∞
246.9
236
*
17402
ICD-8 Finland
Malignant neoplasm of breast, Glandulae
410.0
241.0
241
6
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.8
232.6
838
1881
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
29.4
229.8
315
111
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
6.5
223.9
622
1024
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
91.7
216.4
241
27
ZZR10
NOMESCO Finland
Flap of skin and muscle
45.8
215.5
267
60
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
144.8
212.5
226
16
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
144.2
211.4
225
16
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
425.3
209.2
209
5
L01BC06
ATC
capecitabine; oral
6.1
207.6
602
1046
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
269.3
205.9
210
8
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
12.0
205.3
389
338
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
304.8
204.2
207
7
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
15.3
202.0
343
232
HAC25
NOMESCO Finland
Radical mastectomy
1870.9
199.5
193
*
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
135.6
198.2
212
16
R4110
NOMESCO Finland
Physiotherapy
2.2
196.2
2741
15222
C50.20
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,no histological veryfication
490.7
194.1
193
*
A04AA01
ATC
ondansetron; systemic, rectal
3.6
188.1
929
2772
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
14.8
187.6
323
226
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
7.3
183.0
461
658
8500/3-C50.3
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-inner quadrant of breast
+∞
182.9
175
*
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
163.4
182.3
192
12
9703
FHL
Breast resection
12.7
181.2
334
273
TQB05
NOMESCO Finland
Puncture of skin of trunk
28.1
166.1
230
84
1CD02
NOMESCO Finland
NA
138.0
164.8
176
13
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
+∞
159.8
153
*
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
53.0
159.4
192
37
8010/3-C50.9
ICD-O-3
Carcinoma, NOS, of breast, NOS
+∞
156.7
150
*
FM1FN
NOMESCO Finland
Heart function isotope examination
75.3
155.1
177
24
HAD99
NOMESCO Finland
Other plastic operation on breast
40.2
152.0
193
49
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
150.8
3505
23127
8500/3-C50.1
ICD-O-3
Infiltrating duct carcinoma, NOS, of central portion of breast
+∞
147.2
141
*
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
28.9
146.5
201
71
ZZF00
NOMESCO Finland
Graft of adipose tissue
22.3
146.1
216
99
WB402
NOMESCO Finland
Demanding antibody therapy of primary tumour
35.7
145.0
189
54
I97.2
ICD-10 Finland
Postmastectomy lymphoedema syndrome
170.5
143.9
151
9
C50.59
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, other or undeterminated histology
360.3
142.2
143
*
C50.22
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,lobular tumor
294.4
141.8
144
5
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
25.2
140.4
200
81
9706
FHL
Ablation mammae, includes axillary exploration
1381.2
138.9
135
*
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
26.8
137.2
192
73
5702
FHL
Local lymph node removal (eg armpit, groin)
46.5
137.1
169
37
8500/3-C50.8
ICD-O-3
Infiltrating duct carcinoma, NOS, of overlapping lesion of breast
+∞
136.8
131
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
78.7
129.7
147
19
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
110.1
129.3
141
13
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
194.2
128.9
134
7
C50.39
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, other or undeterminated histology
642.1
128.7
127
*
C50.2
ICD-10 Finland
Malignant neoplasm: Upper-inner quadrant of breast
1265.9
128.4
125
*
WF002
NOMESCO Finland
Radical radiotherapy
5.3
128.2
413
808
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
12.6
126.8
233
189
HAD40
NOMESCO Finland
Mastopexy
30.2
122.5
166
56
1749X
ICD-9 Finland
Malignant neoplasm of female breast, Breast (female), unspecified
251.4
121.2
124
5
1742A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-inner quadrant
1183.7
120.1
117
*
D05.0
ICD-10 Finland
Lobular carcinoma in situ
159.6
119.5
126
8
HA4MT
NOMESCO Finland
Labeling mammary gland pathology with X-ray guidance
60.4
116.4
137
23
WX702
NOMESCO Finland
Supraglottic ventilation device
3.3
112.4
609
1926
Z51.0
ICD-10 Finland
Radiotherapy session
13.8
110.2
194
143
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
55.9
106.6
127
23
HA6HA
NOMESCO Finland
Tomosynthesis assessment of mammary gland specimen
106.8
106.2
116
11
L03AA02
ATC
filgrastim; parenteral
5.2
104.2
343
686
HA3ST
NOMESCO Finland
Removal of lesion of breast with radiological guidance
29.4
104.2
142
49
HA1HA
NOMESCO Finland
Tomosynthesis mammography
24.6
103.4
148
61
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.1
103.2
434
1112
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
104.0
103.1
113
11
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
78.4
102.4
116
15
HWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of mammary gland
43.3
99.4
124
29
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
71.3
98.5
113
16
X21
ICPC
Breast sympt/compl female other
5.1
96.4
322
655
C50.1
ICD-10 Finland
Malignant neoplasm: Central portion of breast
477.6
95.5
95
*
C50.80
ICD-10 Finland
Overall malignant tumor of the mammary gland, no histological veryfication
239.8
92.7
95
*
JN4BD
NOMESCO Finland
Extensive body CT
2.3
92.1
946
4378
C50.5
ICD-10 Finland
Malignant neoplasm: Lower-outer quadrant of breast
907.3
92.0
90
*
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
23.5
91.1
132
57
C50.52
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, lobular tumor
897.0
90.9
89
*
C50.93
ICD-10 Finland
Malignant tumor in other specified localization in mammary gland other or unspecified histology
308.8
89.9
91
*
C50.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of breast
886.8
89.9
88
*
HA1SA
NOMESCO Finland
Expansion mammography
31.7
89.1
119
38
1748X
ICD-9 Finland
Malignant neoplasm of female breast, Other specified sites of female breast
+∞
88.6
85
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
7.3
88.2
220
308
1XC03
NOMESCO Finland
NA
156.5
88.2
93
6
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
12.5
88.1
162
132
C50.50
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, no histological veryfication
436.7
87.2
87
*
PJW99
NOMESCO Finland
Other operation on lymphatic system
118.7
87.0
94
8
C50.12
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,lobular tumor
298.2
86.8
88
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
19.3
86.1
133
70
ZX112
NOMESCO Finland
Subcutaneous
5.9
85.6
250
434
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
+∞
84.5
81
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
9.1
84.2
182
203
HAC10
NOMESCO Finland
Subcutaneous mastectomy with preservation of mamilla
65.3
83.6
97
15
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
+∞
83.4
80
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.1
83.3
481
1586
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
35.2
83.0
108
31
HA2AT
NOMESCO Finland
Cytology of mammary gland with ultrasound guidance
22.1
82.7
122
56
ZXA05
NOMESCO Finland
Left side
1.7
81.0
2369
15980
1745A
ICD-9 Finland
Malignant neoplasm of female breast, Lower-outer quadrant
+∞
80.3
77
*
C77.3
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Axillary and upper limb lymph nodes
43.4
79.6
99
23
8510/3-C50.9
ICD-O-3
Medullary carcinoma, NOS, of breast, NOS
+∞
78.2
75
*
HWH99
NOMESCO Finland
Other reoperation in surgery of mammary gland
38.5
77.6
99
26
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
77.5
651
2707
C50.30
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, no histological veryfication
754.4
76.4
75
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
10.6
76.3
152
146
JN4AD
NOMESCO Finland
Body CT examination
2.5
76.2
672
2868
WB610
NOMESCO Finland
Demanding neoadjuvant therapy of tumour with antibodies
118.1
76.0
82
7
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.5
75.3
369
1075
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
6.8
72.0
188
282
ZX120
NOMESCO Finland
Intravenous
2.2
71.4
813
3921
X19
ICPC
Breast lump/mass female
4.9
70.9
242
504
ZXA00
NOMESCO Finland
Right side
1.6
69.6
2444
17160
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
4.6
68.5
249
554
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
68.3
2182
14941
8480/3-C50.9
ICD-O-3
Mucinous adenocarcinoma of breast, NOS
+∞
67.8
65
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
14.2
66.0
114
81
L02BG06
ATC
exemestane; oral
+∞
65.7
63
*
C50.01
ICD-10 Finland
Malignant tumor of nipple and areola, ductal tumor
67.7
64.3
74
11
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
9.0
64.0
139
157
HA1S1
NOMESCO Finland
Photography of breasts
54.7
63.9
76
14
XX1AD
NOMESCO Finland
Other CT-examination
14.1
63.4
110
79
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
63.1
3358
25796
8503/2-C50.9
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of breast, NOS
+∞
62.5
60
*
C50.3
ICD-10 Finland
Malignant neoplasm: Lower-inner quadrant of breast
314.0
62.4
63
*
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.1
62.1
176
295
8140/3-C50.9
ICD-O-3
Adenocarcinoma, NOS, of breast, NOS
+∞
61.5
59
*
N64.9
ICD-10 Finland
Disorder of breast, unspecified
5.4
60.0
186
348
D24
ICD-10 Finland
Benign neoplasm of breast
3.5
59.2
291
850
N64.5
ICD-10 Finland
Other signs and symptoms in breast
3.4
59.0
307
937
HA1CM
NOMESCO Finland
Mammary gland extensive MRI examination with 3 Tesla magnet
30.2
58.0
78
26
HAA10
NOMESCO Finland
Biopsy of mammary gland
6.3
58.0
160
259
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
13.6
57.5
101
75
N02BE01
ATC
paracetamol; systemic, rectal
1.6
57.4
7557
69429
9725
FHL
Reconstruction of the mammary gland with foreign material (after removal)
49.6
57.1
69
14
ZX070
NOMESCO Finland
Intensity modified radiotherapy
5.5
57.0
174
320
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
3.5
55.7
272
790
D05.7
ICD-10 Finland
Other carcinoma in situ of breast
+∞
55.2
53
*
1743A
ICD-9 Finland
Malignant neoplasm of female breast, Lower-inner quadrant
530.8
53.5
53
*
C50.32
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, lobular tumor
267.2
52.1
53
*
C50.09
ICD-10 Finland
Malignant tumor of nipple and areola, other or undeterminated histology
+∞
52.1
50
*
17409
ICD-8 Finland
Malignant neoplasm of breast, Unspecified
180.9
51.9
54
*
HA1AE
SPAT
NA
4.1
51.8
212
530
WF049
NOMESCO Finland
Radiotherapy of metastasis
3.4
49.2
245
724
9702
FHL
Breast exploration and possible tumor removal
3.4
48.9
253
770
ZSZ00
NOMESCO Finland
Primary repair operation
106.6
48.8
53
5
8520/3-C50.2
ICD-O-3
Lobular carcinoma, NOS, of upper-inner quadrant of breast
+∞
47.9
46
*
XX9TE
NOMESCO Finland
Compementary ultrasound examination
7.9
47.8
112
144
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
46.8
560
2744
ZXE00
NOMESCO Finland
One hour or less
1.4
46.5
3189
25286
1741A
ICD-9 Finland
Malignant neoplasm of female breast, Central portion
236.0
46.0
47
*
X26
ICPC
Fear of breast cancer female
7.0
45.3
115
167
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.5
44.6
356
1432
9719
FHL
Other measure in this category
17.6
44.4
70
40
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
43.4
860
5070
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
4.2
42.9
169
409
L02BG03
ATC
anastrozole; oral
94.5
42.8
47
5
8000/3-C50.9
ICD-O-3
Neoplasm, malignant of breast, NOS
+∞
42.7
41
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
42.0
3254
26216
8522/3-C50.4
ICD-O-3
Infiltrating duct and lobular carcinoma of upper-outer quadrant of breast
+∞
41.7
40
*
N05CB02
ATC
barbiturates in combination with other drugs
2.4
39.9
366
1586
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
39.8
3333
27129
D05
ICD-10 Finland
Carcinoma in situ of breast
+∞
39.6
38
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
39.3
745
4326
L01CA04
ATC
vinorelbine; systemic
8.4
39.0
87
104
HA1BA
NOMESCO Finland
Extensive X-ray mammography
8.0
39.0
90
114
8522/3-C50.9
ICD-O-3
Infiltrating duct and lobular carcinoma of breast, NOS
+∞
38.5
37
*
HA1ST
NOMESCO Finland
Biopsy of mammary gland with sterotactic guidance
24.7
38.3
54
22
8211/3-C50.9
ICD-O-3
Tubular adenocarcinoma of breast, NOS
+∞
37.5
36
*
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
7.2
36.8
91
128
HAD00
NOMESCO Finland
Augmentation mammoplasty
32.1
36.5
48
15
R50.9
ICD-10 Finland
Fever, unspecified
1.6
35.8
915
5795
2330A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Breast
348.4
34.9
35
*
N60.8
ICD-10 Finland
Other benign mammary dysplasias
7.3
34.9
85
117
XX3AT
NOMESCO Finland
Other labeling with ultrasound guidance
15.5
34.6
57
37
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
34.5
354
1619
B01AB05
ATC
enoxaparin; parenteral
1.4
34.4
2525
19975
HA1DA
NOMESCO Finland
Restricted mammography
25.4
34.4
48
19
9721
FHL
Mamilla reconstruction or transposition
51.4
34.4
41
8
8520/3-C50.5
ICD-O-3
Lobular carcinoma, NOS, of lower-outer quadrant of breast
+∞
34.4
33
*
8520/3-C50.1
ICD-O-3
Lobular carcinoma, NOS, of central portion of breast
+∞
33.3
32
*
156
Kela drug reimbursment
Lapatinib
+∞
33.3
32
*
HAD20
NOMESCO Finland
Liposuction of breast
23.6
33.0
47
20
WB321
NOMESCO Finland
Multiple adjuvant therapy of malignancy with biomodifiers
74.4
32.8
37
5
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.4
32.8
284
1196
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
16.9
32.7
52
31
XX1XT
NOMESCO Finland
Other puncture with other radiological guidance
14.5
32.6
55
38
QBJ00
NOMESCO Finland
Liposuction in trunk
6.8
32.5
83
123
C50.0
ICD-10 Finland
Malignant neoplasm: Nipple and areola
318.0
31.9
32
*
HA1RA
SPAT
NA
2.4
31.8
287
1236
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
4.9
31.6
106
220
R92
ICD-10 Finland
Abnormal findings on diagnostic imaging of breast
6.4
31.3
84
133
9708
FHL
Radical mastectomy (Halsted), also involves removal of the parasternal gland
+∞
31.3
30
*
HA1RA
NOMESCO Finland
Combined assessment of mammary gland (mammography and ultrasound)
2.8
31.2
207
750
Z31.6
ICD-10 Finland
General counselling and advice on procreation
11.2
31.1
59
53
N62
ICD-10 Finland
Hypertrophy of breast
2.1
31.1
384
1903
QBA00
NOMESCO Finland
Puncture of skin of trunk
9.0
30.4
65
73
2393A
ICD-9 Finland
Neoplasm of unspecified nature, Breast
5.5
30.2
91
167
L01XE07
ATC
[U] lapatinib; oral
+∞
30.2
29
*
9724
FHL
Breast augmentation or reconstruction with own tissue
24.8
30.0
42
17
Z80.4
ICD-10 Finland
Family history of malignant neoplasm of genital organs
8.0
29.7
68
86
8500/2-C50.5
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of lower-outer quadrant of breast
+∞
29.2
28
*
WX110
NOMESCO Finland
Local anesthesy
1.3
29.1
5287
47304
N61
ICD-10 Finland
Inflammatory disorders of breast
2.8
29.0
191
689
Z3231
NOMESCO Finland
Registered nurse
1.4
28.7
1984
15452
N06AX16
ATC
venlafaxine; oral
1.5
28.6
1037
7138
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
21.1
28.6
42
20
XX2VW
NOMESCO Finland
Radiologic consultation
6.1
28.2
78
129
XX2ET
NOMESCO Finland
NA
+∞
27.1
26
*
A02BC02
ATC
pantoprazole; systemic
1.3
27.0
5453
49201
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
2.7
27.0
186
691
Z40.0
ICD-10 Finland
Prophylactic surgery for risk-factors related to malignant neoplasms
18.7
26.9
41
22
1740A
ICD-9 Finland
Malignant neoplasm of female breast, Nipple and areola
140.3
26.6
28
*
WB303
NOMESCO Finland
Simple adjuvant therapy of malignancy with biomodifiers
16.9
26.5
42
25
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
23.2
26.0
37
16
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
25.6
537
3210
A79
ICPC
Malignancy NOS
4.1
25.3
99
241
8523/3-C50.9
ICD-O-3
Infiltrating duct mixed with other types of carcinoma of breast, NOS
+∞
25.0
24
*
8211/3-C50.4
ICD-O-3
Tubular adenocarcinoma of upper-outer quadrant of breast
+∞
25.0
24
*
8523/3-C50.4
ICD-O-3
Infiltrating duct mixed with other types of carcinoma of upper-outer quadrant of breast
+∞
25.0
24
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
3.3
24.9
129
397
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
5.7
24.9
72
127
3AA13
NOMESCO Finland
NA
14.0
24.8
42
30
L02AE02
ATC
leuprorelin; implant, parenteral
3.7
24.0
105
283
394
Kela drug reimbursment
Palbociclib
+∞
24.0
23
*
1501
Kela drug reimbursment
Palbociclib
+∞
24.0
23
*
8500/2-C50.3
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of lower-inner quadrant of breast
+∞
24.0
23
*
8520/3-C50.8
ICD-O-3
Lobular carcinoma, NOS, of overlapping lesion of breast
+∞
24.0
23
*
8500/2-C50.2
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-inner quadrant of breast
+∞
24.0
23
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
2.9
23.9
149
519
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.4
23.9
202
841
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
23.8
168
634
PJ1AN
NOMESCO Finland
Lymphsystem isotope imaging
20.6
23.8
35
17
1XC13
NOMESCO Finland
NA
240.4
23.6
24
*
TQW99
NOMESCO Finland
Other minor procedure on skin
1.9
23.5
374
2046
8543/3-C50.9
ICD-O-3
Paget disease and intraductal carcinoma of breast of breast, NOS
+∞
22.9
22
*
C507
ICD-10 Finland
NA
+∞
22.9
22
*
PJ5YQ
NOMESCO Finland
NA
+∞
22.9
22
*
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
4.5
22.9
82
184
HAD55
NOMESCO Finland
Incision of periprosthetic capsule of breast
83.6
22.6
25
*
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
3.8
22.4
96
255
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
10.5
22.2
43
41
SPAT1324
SPAT
Screening procedure
0.7
22.1
913
12340
WB131
NOMESCO Finland
Very demanding neoadjuvant cytostatic therapy
62.6
21.8
25
*
Z3226
NOMESCO Finland
Physiotherapist
1.4
21.7
1365
10401
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
21.7
444
2631
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
4.7
21.7
74
158
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
21.4
921
6552
N64.8
ICD-10 Finland
Other specified disorders of breast
4.8
21.3
71
148
OAA41
NOMESCO Finland
Health check based on individual needs
17.4
21.3
33
19
B01AB10
ATC
tinzaparin; parenteral
1.6
21.2
524
3277
8480/3-C50.4
ICD-O-3
Mucinous adenocarcinoma of upper-outer quadrant of breast
+∞
20.8
20
*
8575/3-C50.9
ICD-O-3
Metaplastic carcinoma, NOS, of breast, NOS
+∞
20.8
20
*
8401/3-C50.9
ICD-O-3
Apocrine adenocarcinoma of breast, NOS
+∞
20.8
20
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
3.4
20.3
101
303
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.7
20.3
142
534
ZZQ70
NOMESCO Finland
Free microvascular graft of lymph nodes
+∞
19.8
19
*
8530/3-C50.9
ICD-O-3
Inflammatory carcinoma of breast, NOS
+∞
19.8
19
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
3.6
19.6
88
244
C50.61
ICD-10 Finland
Malignant tumor of the scapula of the mammary gland, ductal tumor
200.3
19.5
20
*
ZSZ10
NOMESCO Finland
Secondary repair operation
34.3
18.9
24
7
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
4.0
18.8
76
193
8211/3-C50.2
ICD-O-3
Tubular adenocarcinoma of upper-inner quadrant of breast
+∞
18.7
18
*
HAF00
NOMESCO Finland
Excision of local recurrence of breast cancer
+∞
18.7
18
*
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
18.7
297
1627
S18
ICPC
Laceration/cut
1.2
18.6
3122
27059
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
6.6
18.3
47
72
Y83.4
ICD-10 Finland
Other reconstructive surgery as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
11.0
18.1
34
31
C49.39
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax other or unspecified tumor
32.9
17.9
23
7
103
Kela drug reimbursment
Diabetes, insulin-treated
0.8
17.9
1143
14531
8401/3-C50.4
ICD-O-3
Apocrine adenocarcinoma of upper-outer quadrant of breast
+∞
17.7
17
*
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
8.3
17.4
38
46
A46
ICD-10 Finland
Erysipelas
1.4
17.1
835
6079
N02AA05
ATC
oxycodone; systemic
1.4
17.0
990
7427
JN4CD
NOMESCO Finland
Very extensive body CT
1.9
17.0
237
1241
HAB30
NOMESCO Finland
Excision of mamilla or areola
19.3
16.8
25
13
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.8
16.8
1018
13043
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
2.9
16.7
103
361
N95.1
ICD-10 Finland
Menopausal and female climacteric states
0.7
16.7
484
6970
8510/3-C50.4
ICD-O-3
Medullary carcinoma, NOS, of upper-outer quadrant of breast
+∞
16.7
16
*
335
Kela drug reimbursment
Lapatinib
+∞
16.7
16
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.6
16.5
395
2447
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
7.6
16.5
38
50
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.1
16.5
178
840
SPAT1269
SPAT
Other puncture and/or drainage
4.2
16.5
62
148
ZXC90
NOMESCO Finland
Use of absorbable mesh in surgery
170.2
16.5
17
*
ZSP00
NOMESCO Finland
Procedure related to previous procedure classified in chapter P
27.5
16.5
22
8
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
3.4
16.1
77
226
X79
ICPC
Benign neoplasm breast female
13.5
15.9
27
20
HA1AT
SPAT
NA
12.2
15.8
28
23
ZZS50
NOMESCO Finland
Insertion of tissue expander
60.1
15.7
18
*
HAB20
NOMESCO Finland
Excision of lactiferous duct
5.0
15.7
50
101
8575/3-C50.4
ICD-O-3
Metaplastic carcinoma, NOS, of upper-outer quadrant of breast
+∞
15.6
15
*
8500/2-C50.1
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of central portion of breast
+∞
15.6
15
*
8507/3-C50.9
ICD-O-3
Invasive micropapillary carcinoma of breast of breast, NOS
+∞
15.6
15
*
8520/3-C50.3
ICD-O-3
Lobular carcinoma, NOS, of lower-inner quadrant of breast
+∞
15.6
15
*
HA1DM
NOMESCO Finland
Mammary gland very extensive MRI examination with 3 Tesla magnet
38.1
15.4
19
5
6117B
ICD-9 Finland
Other disorders of breast, Signs and symptoms in breast[TUMOR MAMMAE]
3.3
15.1
76
233
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
2.6
15.1
107
410
J01DB01
ATC
cefalexin; oral
1.2
15.0
6473
61105
I10
ICD-10 Finland
Essential (primary) hypertension
0.8
15.0
3898
42871
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.5
14.8
468
3114
HA5CB
NOMESCO Finland
Galactography
6.0
14.7
40
67
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
16.5
14.7
23
14
A10BA02
ATC
metformin; oral
0.8
14.7
1252
15390
9020/3-C50.9
ICD-O-3
Phyllodes tumor, malignant of breast, NOS
+∞
14.6
14
*
Z80.8
ICD-10 Finland
Family history of malignant neoplasm of other organs or systems
5.7
14.6
41
72
ZZS55
NOMESCO Finland
Distension of tissue expander
80.2
14.6
16
*
Z51.5
ICD-10 Finland
Palliative care
1.6
14.5
342
2116
9729
FHL
Other measure in this category
5.0
14.5
46
93
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
14.3
173
856
TQW11
NOMESCO Finland
Vacuum treatment of wound
2.4
14.3
125
535
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.2
14.0
139
634
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
13.9
183
941
M05BA02
ATC
clodronic acid; systemic
6.8
13.9
34
50
PG1BD
NOMESCO Finland
Extensive CT angiography of tissue graft, e.g. assessment of TRAN graft
53.4
13.8
16
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
13.7
1361
11019
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
0.7
13.6
515
7093
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.5
13.6
403
2645
8522/3-C50.5
ICD-O-3
Infiltrating duct and lobular carcinoma of lower-outer quadrant of breast
+∞
13.5
13
*
8522/3-C50.2
ICD-O-3
Infiltrating duct and lobular carcinoma of upper-inner quadrant of breast
+∞
13.5
13
*
1744A
ICD-10 Finland
NA
+∞
13.5
13
*
8504/2-C50.9
ICD-O-3
Encapsulated papillary carcinoma of breast, NOS
+∞
13.5
13
*
QBA10
NOMESCO Finland
Incision of skin of trunk
3.2
13.5
70
220
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
0.8
13.5
1006
12585
C50.02
ICD-10 Finland
Malignant tumor of nipple and areola, lobular tumor
140.1
13.4
14
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.4
13.4
601
4304
M05BX04
ATC
denosumab; parenteral
1.5
13.4
405
2667
SPAT1152
SPAT
Removal of foreign body from under the skin
1.9
13.4
185
968
J01MA12
ATC
levofloxacin; systemic
1.3
13.2
1152
9169
B29
ICPC
Lymph/immune mech sympt/complt other
4.6
13.2
45
99
-1
ICD-10 Finland
NA
1.8
13.1
226
1279
TPX10
NOMESCO Finland
Implantation of vascular injection port
1.9
13.0
178
926
T90
ICPC
Diabetes non-insulin dependent
0.8
13.0
1006
12528
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
8.3
13.0
28
34
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
9.3
12.9
26
28
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.1
12.9
151
740
QWF00
NOMESCO Finland
Reoperation for insufficiency of suture in plastic surgery of skin
22.5
12.9
18
8
WB600
NOMESCO Finland
Neoadjuvant therapy of primary tumour with antibodies                        
50.0
12.8
15
*
2170A
ICD-9 Finland
Benign neoplasm of breast[NEOPLASMA BENIGNUM MAMMAE]
2.9
12.8
77
269
HA1AA
SPAT
NA
2.2
12.7
133
622
X18
ICPC
Breast pain female
2.2
12.6
125
571
THA00
NOMESCO Finland
Needle biopsy of mamilla
6.8
12.6
31
46
L01EF01
ATC
palbociclib; oral
+∞
12.5
12
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
12.5
1331
10864
WW500
NOMESCO Finland
Blood transfusion
1.7
12.5
240
1402
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.3
12.2
106
455
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.5
12.1
355
2324
N05CF01
ATC
zopiclone; oral
1.2
12.1
2556
22425
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
3.3
11.9
59
181
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.6
11.8
302
1911
T81.9
ICD-10 Finland
Unspecified complication of procedure
2.2
11.5
116
534
9680/3-C50.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of breast, NOS
+∞
11.5
11
*
8543/3-C50.1
ICD-O-3
Paget disease and intraductal carcinoma of breast of central portion of breast
+∞
11.5
11
*
1XC14
NOMESCO Finland
NA
+∞
11.5
11
*
YX9CD
NOMESCO Finland
Other very extensive CT eamination for dose design of radiotherapy
11.8
11.3
20
17
ZZR70
NOMESCO Finland
Perforator flaps
35.0
11.2
14
*
QCJ00
NOMESCO Finland
Liposuction in upper limb
17.0
11.2
17
10
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
11.1
7259
69879
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.7
11.0
242
1475
WF004
NOMESCO Finland
Palliative radiotherapy
2.3
10.8
94
406
8097/3-C44.3
ICD-O-3
Basal cell carcinoma, nodular of skin of other and unspecified parts of face
15.5
10.8
17
11
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
0.7
10.8
398
5506
HAD57
NOMESCO Finland
Resection of periprosthetic capsule of breast
21.4
10.7
15
7
Z44.3
ICD-10 Finland
Fitting and adjustment of external breast prosthesis
60.0
10.6
12
*
HAC99
NOMESCO Finland
Other mastectomy
60.0
10.6
12
*
HAA01
NOMESCO Finland
Suture of mammary gland
60.0
10.6
12
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
10.6
492
3546
A04AA03
ATC
tropisetron; systemic
4.2
10.6
39
94
JN6AD
NOMESCO Finland
CT of torso and neck
2.5
10.5
78
308
N05BA04
ATC
oxazepam; oral
1.2
10.5
1904
16430
WX704
NOMESCO Finland
Intubation
1.4
10.4
433
3055
ZZQ60
NOMESCO Finland
Free microvascular graft of nerve
+∞
10.4
10
*
9829
FHL
Other measure in this category
+∞
10.4
10
*
8524/3-C50.9
ICD-O-3
Infiltrating lobular mixed with other types of carcinoma of breast, NOS
+∞
10.4
10
*
8507/3-C50.4
ICD-O-3
Invasive micropapillary carcinoma of breast of upper-outer quadrant of breast
+∞
10.4
10
*
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
16.0
10.3
16
10
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
2.0
10.2
118
580
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
0.9
10.2
5007
53175
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
0.8
10.2
1499
17495
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.2
10.2
1700
14544
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
10.1
603
4541
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
1.4
10.0
492
3586
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
2.6
9.9
68
261
Z08.9
ICD-10 Finland
Follow-up examination after unspecified treatment for malignant neoplasm
3.5
9.8
44
126
WW200
SPAT
NA
0.7
9.7
379
5190
SAA01
NOMESCO Finland
Simple examination of mouth
0.9
9.5
4647
49502
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
2.0
9.5
114
570
D70.89
ICD-10 Finland
Neutropenic splenomegaly
2.4
9.4
78
329
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
3.3
9.4
45
136
C50.69
ICD-10 Finland
Malignant tumor of the scapula of the mammary gland, other or undeterminated histology
100.1
9.4
10
*
9710
FHL
Existence of a relapse
100.1
9.4
10
*
JN5AN
NOMESCO Finland
Total body isotope imaging
17.5
9.4
14
8
8540/3-C50.0
ICD-O-3
Paget disease, mammary of nipple
+∞
9.4
9
*
N60.1
ICD-10 Finland
Diffuse cystic mastopathy
2.3
9.3
81
352
205
Kela drug reimbursment
Chronic hypertension
0.8
9.3
1489
17254
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.7
9.1
59
219
GD1AD
NOMESCO Finland
Thorax CT examination
1.6
9.1
232
1474
E66.01
ICD-10 Finland
Obesity due to excess calories
0.7
9.0
254
3673
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.3
9.0
540
4069
SFA10
NOMESCO Finland
Fillning on one surface of tooth
0.9
8.9
3212
34988
C08CA01
ATC
amlodipine; oral
0.9
8.8
2103
23608
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
8.6
8.8
18
21
ZXC82
NOMESCO Finland
Microsurgical
10.7
8.8
16
15
L02AE03
ATC
goserelin; implant
2.7
8.8
58
219
I89.0
ICD-10 Finland
Lymphoedema, not elsewhere classified
2.5
8.7
63
249
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
0.9
8.6
3520
38061
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
2.1
8.6
91
433
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
5.8
8.6
23
40
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.4
8.6
477
3553
C10AA01
ATC
simvastatin; oral
0.9
8.6
2652
29222
9705
FHL
Subcutaneous mastectomy
11.5
8.5
15
13
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
1.6
8.5
187
1143
SPAT1262
SPAT
Handing over of treatment supplies
0.8
8.5
770
9451
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
0.7
8.4
286
4008
QBE35
NOMESCO Finland
Repair of skin defect in trunk after surgery or injury
6.0
8.4
22
37
8501/2-C50.9
ICD-O-3
Comedocarcinoma, noninfiltrating of breast, NOS
+∞
8.3
8
*
8500/2-C50.8
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of overlapping lesion of breast
+∞
8.3
8
*
8480/3-C50.3
ICD-O-3
Mucinous adenocarcinoma of lower-inner quadrant of breast
+∞
8.3
8
*
9120/3-C50.9
ICD-O-3
Hemangiosarcoma of breast, NOS
+∞
8.3
8
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
0.7
8.3
293
4080
A10AE04
ATC
insulin glargine; parenteral
0.7
8.1
264
3725
N81.1
ICD-10 Finland
Cystocele
0.8
8.1
444
5790
C49.30
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax without histology
22.0
8.0
11
5
XX9CN
NOMESCO Finland
NA
22.0
8.0
11
5
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
0.9
8.0
2903
31680
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
4.1
7.9
29
71
E66.8
ICD-10 Finland
Other obesity
0.6
7.9
153
2380
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.3
7.8
483
3657
XX9KE
NOMESCO Finland
Ultrasound examination with contrast
10.8
7.8
14
13
C79.39
ICD-10 Finland
Secondary malignant tumor of the meninges, ventricle or other part of the brain
6.9
7.7
18
26
PD2BD
NOMESCO Finland
Extensive CT angiography of pelvic organs
18.3
7.6
11
6
PJ4AT
NOMESCO Finland
Labeling lymphnode with ultrasound guidance
8.0
7.6
16
20
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
3.4
7.5
34
100
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.3
7.5
444
3344
1746A
ICD-9 Finland
Malignant neoplasm of female breast, Axillary tail
80.1
7.4
8
*
9822
FHL
Myocutaneous graft
80.1
7.4
8
*
8097/3-C44.5
ICD-O-3
Basal cell carcinoma, nodular of skin of trunk
80.1
7.4
8
*
SDA02
NOMESCO Finland
Parodonthologic therapy
0.9
7.4
1899
21254
WF099
NOMESCO Finland
Other radiotherapy
3.1
7.4
38
124
8480/3-C50.5
ICD-O-3
Mucinous adenocarcinoma of lower-outer quadrant of breast
+∞
7.3
7
*
8480/3-C50.2
ICD-O-3
Mucinous adenocarcinoma of upper-inner quadrant of breast
+∞
7.3
7
*
Y16
ICPC
Breast symptom/complaint male
+∞
7.3
7
*
8509/2-C50.9
ICD-O-3
Solid papillary carcinoma in situ of breast, NOS
+∞
7.3
7
*
8200/3-C50.9
ICD-O-3
Adenoid cystic carcinoma of breast, NOS
+∞
7.3
7
*
8503/3-C50.4
ICD-O-3
Intraductal papillary adenocarcinoma with invasion of upper-outer quadrant of breast
+∞
7.3
7
*
8503/2-C50.4
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of upper-outer quadrant of breast
+∞
7.3
7
*
L01EH01
ATC
lapatinib; oral
+∞
7.3
7
*
8010/3-C50.4
ICD-O-3
Carcinoma, NOS, of upper-outer quadrant of breast
+∞
7.3
7
*
8523/3-C50.5
ICD-O-3
Infiltrating duct mixed with other types of carcinoma of lower-outer quadrant of breast
+∞
7.3
7
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
1.6
7.3
164
1014
6101A
ICD-9 Finland
Benign mammary dysplasias, Diffuse cystic mastopathy
2.5
7.2
52
208
A21
ICPC
Risk factor for malignancy
5.4
7.2
20
37
SDA01
NOMESCO Finland
Simple parodonthologic therapy
0.8
7.2
1341
15380
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.4
7.2
305
2171
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.3
7.2
442
3351
A26
ICPC
Fear of cancer, NOS
2.7
7.2
44
161
9722
FHL
Reduction plastic and possible mamilla transposition
3.0
7.1
38
127
N06AB05
ATC
paroxetine; oral
1.4
7.1
376
2785
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
0.7
7.1
215
3066
OAB47
SPAT
NA
0.5
7.0
42
896
R06AE07
ATC
cetirizine; oral
1.1
7.0
3411
31552
G03FA14
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
0.8
6.9
370
4842
TQX05
NOMESCO Finland
Skin puncture, unspecified location
4.4
6.9
23
52
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.8
6.9
1276
14646
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
0.2
6.8
9
374
9844
FHL
Musculocutaneous tongue
39.9
6.7
8
*
M70.6
ICD-10 Finland
Trochanteric bursitis
0.8
6.7
832
9897
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
2.7
6.7
44
166
A87
ICPC
Complication of medical treatment
2.4
6.7
52
217
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.3
6.6
526
4130
GA5AA
NOMESCO Finland
Rib X-ray examination
3.5
6.6
28
79
P01BA02
ATC
hydroxychloroquine; oral
0.8
6.6
442
5611
L17
ICPC
Foot/toe symptom/complaint
0.9
6.5
1491
16839
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
2.8
6.4
39
142
G47.3
ICD-10 Finland
Sleep apnoea
0.8
6.4
781
9307
SAA02
NOMESCO Finland
Basic examination of mouth
0.9
6.4
4135
43809
KMAK
NOMESCO Finland
NA
0.9
6.4
3177
34163
HA1DT
NOMESCO Finland
Mammary gland biopsy with MRI guidance
69.8
6.4
7
*
L03
ICPC
Low back symptom/complaint
0.9
6.4
1421
16091
SPAT1310
SPAT
Counselling related to known health issue
0.9
6.4
1869
20759
L88
ICPC
Rheumatoid/seropositive arthritis
0.7
6.3
148
2215
K02.1
ICD-10 Finland
Caries of dentine
0.9
6.3
3335
35741
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
0.5
6.3
56
1053
6119X
ICD-9 Finland
Other disorders of breast, Unspecified breast disorder
9.2
6.3
12
13
C05.1
ICD-10 Finland
Malignant neoplasm: Soft palate
9.2
6.3
12
13
L01EF03
ATC
abemaciclib; oral
+∞
6.2
6
*
3030
Kela drug reimbursment
Abemaciclib
+∞
6.2
6
*
8010/2-C50.9
ICD-O-3
Carcinoma in situ, NOS, of breast, NOS
+∞
6.2
6
*
8507/3-C50.2
ICD-O-3
Invasive micropapillary carcinoma of breast of upper-inner quadrant of breast
+∞
6.2
6
*
1515
Kela drug reimbursment
NA
+∞
6.2
6
*
173
Kela drug reimbursment
Trastuzumab injection
+∞
6.2
6
*
8541/3-C50.9
ICD-O-3
Paget disease and infiltrating duct carcinoma of breast of breast, NOS
+∞
6.2
6
*
8480/3-C50.1
ICD-O-3
Mucinous adenocarcinoma of central portion of breast
+∞
6.2
6
*
8201/3-C50.9
ICD-O-3
Cribriform carcinoma, NOS, of breast, NOS
+∞
6.2
6
*
8201/3-C50.4
ICD-O-3
Cribriform carcinoma, NOS, of upper-outer quadrant of breast
+∞
6.2
6
*
8211/3-C50.5
ICD-O-3
Tubular adenocarcinoma of lower-outer quadrant of breast
+∞
6.2
6
*
8522/3-C50.8
ICD-O-3
Infiltrating duct and lobular carcinoma of overlapping lesion of breast
+∞
6.2
6
*
21799
ICD-8 Finland
Benign neoplasm of breast
1.9
6.2
86
459
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.6
6.2
135
831
N81.6
ICD-10 Finland
Rectocele
0.8
6.2
445
5600
L03.3
ICD-10 Finland
Cellulitis of trunk
2.5
6.2
44
175
A14AB01
ATC
nandrolone; parenteral
3.9
6.2
23
59
A10BH01
ATC
sitagliptin; oral
0.8
6.1
339
4410
EBA00
NOMESCO Finland
Extraction of tooth
0.9
6.1
1605
17970
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
1.8
6.1
89
483
K85
ICPC
Elevated blood pressure
0.8
6.1
834
9827
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
0.7
6.1
248
3368
N60.0
ICD-10 Finland
Solitary cyst of breast
2.2
6.0
55
248

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_BREAST_ERNEG – Malignant neoplasm of breast, HER-negative

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).