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Carcinoma in situ of breast, intraductal

CD2_INSITU_BREAST_INTRADUCTAL

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D05.1&
  • Cause of death: ICD-10 D05.1&

2 out of 7 registries used, show all original rules.

3132

4. Check minimum number of events

None

3132

5. Include endpoints

None

3132

6. Filter based on genotype QC (FinnGen only)

3132

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D05
Name in latin
Carcinoma in situ intraductale mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3132 3132 -
Unadjusted period prevalence (%) 1.07 1.07 -
Median age at first event (years) 60.34 60.34 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2756
Matched controls
27560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
775.0
323.0
1341
34
HAC20
NOMESCO Finland
Total mastectomy
13.7
323.0
887
921
HAB40
NOMESCO Finland
Wedge excision of mammary gland
12.4
323.0
1022
1249
HA1AA
NOMESCO Finland
X-ray mammography
10.9
323.0
1243
1928
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
8.1
323.0
844
1425
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
10.0
323.0
1044
1583
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
11.9
323.0
817
943
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
17.7
323.0
784
606
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
97.2
323.0
441
54
HAB99
NOMESCO Finland
Other partial excision of mammary gland
15.4
323.0
573
463
PJA12
NOMESCO Finland
Sentinel node biopsy
26.3
323.0
1802
1845
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
4503599627370496.0
323.0
2754
*
115
Kela drug reimbursment
Breast cancer
6.4
318.0
1001
2255
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
23.7
308.7
453
227
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
8.3
293.5
727
1146
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
23.8
285.8
418
205
TQW20
NOMESCO Finland
Tatoe
25.1
239.4
344
156
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
12.5
237.3
449
422
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.9
211.9
1172
4393
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
12.8
211.2
394
355
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
7.3
210.0
553
914
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
11.1
200.0
401
417
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
9.6
195.6
427
519
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
7.9
185.8
460
685
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
71.3
184.2
211
32
C50
ICD-10 Finland
Malignant neoplasm of breast
10.1
182.9
385
436
C50.99
ICD-10 Finland
Breast, unspecified
8.6
182.7
424
569
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
10.0
169.6
358
405
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
84.8
162.6
182
23
L02BA01
ATC
tamoxifen; oral
6.3
158.1
460
849
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
9.3
156.3
343
414
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.0
153.1
1355
6751
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
11.1
150.6
299
299
XX3DW
NOMESCO Finland
Time consuming IT work
4.4
149.1
617
1685
X76
ICPC
Malignant neoplasm breast female
10.0
145.7
306
340
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
10.7
138.9
280
287
L02BG04
ATC
letrozole; oral
4.4
136.9
561
1505
ZZR10
NOMESCO Finland
Flap of skin and muscle
19.7
135.5
209
114
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
6.1
134.8
398
740
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
24.0
120.4
174
77
N63
ICD-10 Finland
Unspecified lump in breast
4.5
120.4
482
1251
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
9.4
115.0
249
289
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
6.7
112.7
307
508
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
33.0
108.8
144
46
HAE99
NOMESCO Finland
Other reconstruction of breast
15.8
108.7
182
123
D05.0
ICD-10 Finland
Lobular carcinoma in situ
72.0
108.5
124
18
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
9.5
107.9
231
262
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
9.2
106.1
232
273
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
21.8
105.6
157
76
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
4.8
105.6
384
896
HA4MT
NOMESCO Finland
Labeling mammary gland pathology with X-ray guidance
73.6
105.3
120
17
HA6BA
NOMESCO Finland
Breast tomosynthesis specimen
10.9
99.9
198
194
ZZF00
NOMESCO Finland
Graft of adipose tissue
16.4
99.6
164
106
H02AB02
ATC
dexamethasone; systemic
3.3
99.2
589
2107
HA3ST
NOMESCO Finland
Removal of lesion of breast with radiological guidance
39.3
97.6
124
33
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
4.4
97.2
389
995
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
468.0
91.8
91
*
Z31.5
ICD-10 Finland
Genetic counselling
4.8
87.4
316
726
WF003
NOMESCO Finland
Adjuvant radiotherapy
5.3
83.5
271
552
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
7.7
83.3
203
283
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
17.1
81.2
131
80
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
8.1
80.8
189
247
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
10.5
78.0
157
158
XX1XN
NOMESCO Finland
Other isotope examination
11.7
75.8
144
129
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
5.4
74.3
236
467
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
4.9
72.3
252
553
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
12.4
72.1
133
112
ZX080
NOMESCO Finland
Image guided radiotherapy
6.5
68.8
188
308
WX702
NOMESCO Finland
Supraglottic ventilation device
4.0
67.9
296
808
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
12.1
67.5
126
109
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
9.0
67.3
147
171
A04AA02
ATC
granisetron; systemic, transdermal
3.5
67.3
351
1112
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
66.3
1223
7736
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
7.5
65.6
161
226
WX402
NOMESCO Finland
General anaesthesia
2.5
64.8
621
2904
ZXA05
NOMESCO Finland
Left side
2.1
63.4
907
5129
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
6.2
60.9
172
294
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.0
60.6
260
697
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
5.1
60.6
202
421
A03FA01
ATC
metoclopramide; systemic, rectal
2.1
60.4
844
4707
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
4.8
59.1
209
464
R4110
NOMESCO Finland
Physiotherapy
2.1
58.4
904
5245
ZX090
NOMESCO Finland
Other technic of radiotherapy
5.2
58.2
189
382
HA1BG
NOMESCO Finland
MRI examination of mammary gland with high intensity magnet
10.3
57.5
116
117
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
6.8
56.5
148
228
HA1SA
NOMESCO Finland
Expansion mammography
16.5
55.9
91
57
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
17.2
54.5
87
52
L03AA13
ATC
pegfilgrastim; parenteral
3.6
53.5
256
752
ZXA00
NOMESCO Finland
Right side
2.0
53.2
929
5609
WZC30
NOMESCO Finland
Teaching
2.4
52.6
495
2263
HAC10
NOMESCO Finland
Subcutaneous mastectomy with preservation of mamilla
33.2
51.9
68
21
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
6.0
51.4
148
259
N64.9
ICD-10 Finland
Disorder of breast, unspecified
8.3
51.2
117
147
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
50.6
864
5150
TQB05
NOMESCO Finland
Puncture of skin of trunk
9.5
50.6
106
115
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
5.3
50.4
161
319
8503/2-C50.9
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of breast, NOS
80.2
49.1
55
7
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
5.1
48.7
160
327
ZSZ00
NOMESCO Finland
Primary repair operation
78.8
48.1
54
7
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.8
47.9
213
587
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.3
47.6
257
828
HA1ST
NOMESCO Finland
Biopsy of mammary gland with sterotactic guidance
34.6
47.1
61
18
HAD99
NOMESCO Finland
Other plastic operation on breast
11.5
46.9
89
80
N64.5
ICD-10 Finland
Other signs and symptoms in breast
5.0
46.2
156
329
HAD40
NOMESCO Finland
Mastopexy
12.7
46.0
83
67
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
16.4
42.6
69
43
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
6.3
41.6
114
187
X21
ICPC
Breast sympt/compl female other
4.8
41.6
144
312
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
10.0
41.4
84
86
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
40.0
1233
8795
A04AA55
ATC
palonosetron, combinations; systemic
3.5
39.9
198
597
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
6.1
39.7
112
191
NK6AN
NOMESCO Finland
Total body bone isotope imaging
4.7
39.4
139
307
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
12.3
38.9
71
59
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.5
38.5
118
223
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
9.4
38.2
80
87
HWH99
NOMESCO Finland
Other reoperation in surgery of mammary gland
18.5
37.5
58
32
Z3231
NOMESCO Finland
Registered nurse
1.8
36.1
795
5062
HWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of mammary gland
13.8
35.3
61
45
D05.7
ICD-10 Finland
Other carcinoma in situ of breast
96.3
34.8
38
*
D24
ICD-10 Finland
Benign neoplasm of breast
4.2
34.5
138
345
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.4
33.7
311
1387
HA2AT
NOMESCO Finland
Cytology of mammary gland with ultrasound guidance
9.4
33.1
69
75
N60.8
ICD-10 Finland
Other benign mammary dysplasias
11.5
33.0
62
55
A04AD12
ATC
aprepitant; systemic
4.0
32.9
137
356
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
32.7
1161
8454
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
10.1
32.3
65
66
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
3.9
31.9
135
356
R92
ICD-10 Finland
Abnormal findings on diagnostic imaging of breast
11.8
31.9
59
51
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
6.9
31.7
80
118
N02BE01
ATC
paracetamol; systemic, rectal
2.0
31.5
2469
22319
8500/2-C50.5
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of lower-outer quadrant of breast
161.8
30.7
32
*
HA6HA
NOMESCO Finland
Tomosynthesis assessment of mammary gland specimen
17.4
30.6
48
28
L02BG06
ATC
exemestane; oral
4.3
28.9
111
268
D05
ICD-10 Finland
Carcinoma in situ of breast
55.6
28.2
33
6
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
8.6
28.0
61
72
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
5.5
26.7
80
148
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
5.7
26.1
76
136
8500/2-C50.2
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-inner quadrant of breast
263.0
25.7
26
*
Z3226
NOMESCO Finland
Physiotherapist
1.8
25.5
552
3438
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
7.8
25.0
58
76
HA1HA
NOMESCO Finland
Tomosynthesis mammography
7.8
24.7
57
74
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
24.5
228
1014
HAA10
NOMESCO Finland
Biopsy of mammary gland
6.1
24.2
67
113
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.7
23.8
172
666
B01AB05
ATC
enoxaparin; parenteral
1.6
23.7
895
6470
X26
ICPC
Fear of breast cancer female
6.5
23.2
61
96
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
6.0
23.1
64
108
QBJ00
NOMESCO Finland
Liposuction in trunk
7.4
23.0
55
76
ZXE00
NOMESCO Finland
One hour or less
1.5
22.7
1078
8195
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
3.7
22.1
100
281
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
22.1
381
2191
HAD20
NOMESCO Finland
Liposuction of breast
14.6
21.6
36
25
8500/2-C50.3
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of lower-inner quadrant of breast
221.7
21.6
22
*
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
8.5
21.6
47
56
HAD00
NOMESCO Finland
Augmentation mammoplasty
31.4
21.5
28
9
Z51.0
ICD-10 Finland
Radiotherapy session
5.4
21.5
65
123
1CD02
NOMESCO Finland
NA
5.0
21.4
69
140
8543/3-C50.9
ICD-O-3
Paget disease and intraductal carcinoma of breast of breast, NOS
211.5
20.6
21
*
8500/3-C50.8
ICD-O-3
Infiltrating duct carcinoma, NOS, of overlapping lesion of breast
9.9
20.6
41
42
N62
ICD-10 Finland
Hypertrophy of breast
2.4
20.5
180
777
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
5.3
20.0
61
117
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
19.8
310
1721
L02BG03
ATC
anastrozole; oral
3.1
19.3
111
374
TQW99
NOMESCO Finland
Other minor procedure on skin
2.4
19.2
167
721
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
6.4
19.1
50
79
FM1FN
NOMESCO Finland
Heart function isotope examination
6.3
19.0
50
80
C05.1
ICD-10 Finland
Malignant neoplasm: Soft palate
70.4
18.7
21
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
4.5
18.7
67
153
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
17.2
18.7
29
17
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
6.7
18.1
46
70
XX3AT
NOMESCO Finland
Other labeling with ultrasound guidance
15.4
17.9
29
19
C50.20
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,no histological veryfication
5.9
17.7
49
84
8500/3-C50.2
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-inner quadrant of breast
4.2
17.7
67
162
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
17.4
1096
8692
X19
ICPC
Breast lump/mass female
3.6
17.3
79
225
C50.01
ICD-10 Finland
Malignant tumor of nipple and areola, ductal tumor
11.6
17.0
31
27
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
4.9
16.9
55
114
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
3.1
16.9
96
321
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
5.1
16.8
53
106
ZX120
NOMESCO Finland
Intravenous
1.9
16.8
264
1463
8500/3-C50.3
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-inner quadrant of breast
7.1
16.6
40
57
HA1CM
NOMESCO Finland
Mammary gland extensive MRI examination with 3 Tesla magnet
8.0
16.5
37
47
8500/2-C50.1
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of central portion of breast
171.0
16.5
17
*
I97.2
ICD-10 Finland
Postmastectomy lymphoedema syndrome
5.9
16.3
45
77
L03AA14
ATC
lipegfilgrastim; parenteral
3.1
16.0
91
303
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
6.9
15.9
39
57
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
5.9
15.9
44
76
N06AX16
ATC
venlafaxine; oral
1.6
15.8
408
2637
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
5.6
15.7
45
81
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
15.2
196
1008
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.6
15.0
67
188
ZX112
NOMESCO Finland
Subcutaneous
3.2
15.0
79
253
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.4
14.9
72
216
C50.39
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, other or undeterminated histology
7.6
14.9
34
45
ZZS55
NOMESCO Finland
Distension of tissue expander
25.2
14.7
20
8
N64.8
ICD-10 Finland
Other specified disorders of breast
5.8
14.6
41
72
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
5.2
14.5
44
85
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
14.5
2435
22789
C50.93
ICD-10 Finland
Malignant tumor in other specified localization in mammary gland other or unspecified histology
7.2
14.3
34
48
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
3.7
14.3
62
171
S18
ICPC
Laceration/cut
1.4
14.1
1086
8826
HA5CB
NOMESCO Finland
Galactography
12.0
14.1
25
21
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
7.8
13.8
31
40
JN4BD
NOMESCO Finland
Extensive body CT
1.7
13.8
288
1751
PJW99
NOMESCO Finland
Other operation on lymphatic system
5.3
13.6
41
79
HA4GT
NOMESCO Finland
Labeling mammary gland pathology with galactographic guidance
14.8
13.6
22
15
9703
FHL
Breast resection
3.7
13.0
55
149
8500/3-C50.1
ICD-O-3
Infiltrating duct carcinoma, NOS, of central portion of breast
5.3
12.8
38
72
8500/3-C50.5
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-outer quadrant of breast
4.2
12.6
47
114
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
12.6
172
906
1XC03
NOMESCO Finland
NA
6.7
12.5
31
47
XX1XT
NOMESCO Finland
Other puncture with other radiological guidance
6.7
12.5
31
47
8504/2-C50.9
ICD-O-3
Encapsulated papillary carcinoma of breast, NOS
130.6
12.4
13
*
HAC25
NOMESCO Finland
Radical mastectomy
5.0
12.1
38
77
J01DB01
ATC
cefalexin; oral
1.4
11.9
2147
19749
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.9
11.8
166
884
HA1AE
SPAT
NA
3.0
11.7
67
228
WB402
NOMESCO Finland
Demanding antibody therapy of primary tumour
5.0
11.5
36
73
XX1AD
NOMESCO Finland
Other CT-examination
5.5
11.5
33
61
8500/2-C50.8
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of overlapping lesion of breast
+∞
11.5
11
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
5.1
11.4
35
70
WX400
NOMESCO Finland
Inhalation anesthesy
2.2
11.3
119
562
ZXA10
NOMESCO Finland
Bilateral
1.5
11.3
496
3609
L02AE03
ATC
goserelin; implant
4.1
11.3
43
107
XX2ET
NOMESCO Finland
NA
20.1
11.1
16
8
Z40.0
ICD-10 Finland
Prophylactic surgery for risk-factors related to malignant neoplasms
13.9
11.0
18
13
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
4.7
10.9
36
78
WX110
NOMESCO Finland
Local anesthesy
1.3
10.9
1757
15740
8523/3-C50.9
ICD-O-3
Infiltrating duct mixed with other types of carcinoma of breast, NOS
28.1
10.7
14
5
C50.50
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, no histological veryfication
5.8
10.7
29
50
2330A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Breast
21.5
10.7
15
7
HA1BA
NOMESCO Finland
Extensive X-ray mammography
3.9
10.7
42
108
C50.22
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,lobular tumor
4.3
10.5
38
90
8543/3-C50.1
ICD-O-3
Paget disease and intraductal carcinoma of breast of central portion of breast
+∞
10.4
10
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
3.0
10.4
58
196
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
10.2
82
341
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
5.0
10.1
31
62
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
10.0
199
1193
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.6
10.0
68
261
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.1
9.9
51
164
HAB20
NOMESCO Finland
Excision of lactiferous duct
6.3
9.8
25
40
ZXC90
NOMESCO Finland
Use of absorbable mesh in surgery
100.4
9.4
10
*
X79
ICPC
Benign neoplasm breast female
30.1
9.4
12
*
HA1WT
NOMESCO Finland
NA
+∞
9.4
9
*
8501/2-C50.9
ICD-O-3
Comedocarcinoma, noninfiltrating of breast, NOS
+∞
9.4
9
*
Z2221
NOMESCO Finland
Medical doctor
1.3
9.1
684
5446
WX704
NOMESCO Finland
Intubation
1.7
9.0
179
1073
C50.30
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, no histological veryfication
7.0
9.0
21
30
XX2VW
NOMESCO Finland
Radiologic consultation
5.0
8.9
27
54
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.7
8.7
361
4819
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
3.7
8.5
35
95
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.8
8.5
141
802
Z80.4
ICD-10 Finland
Family history of malignant neoplasm of genital organs
6.0
8.4
22
37
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
3.6
8.4
36
101
HA1S1
NOMESCO Finland
Photography of breasts
12.8
8.4
14
11
A04AA01
ATC
ondansetron; systemic, rectal
1.7
8.3
186
1154
N95.1
ICD-10 Finland
Menopausal and female climacteric states
0.6
8.3
158
2442
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.1
8.2
94
465
M05BX04
ATC
denosumab; parenteral
1.7
8.0
156
934
C50.59
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, other or undeterminated histology
4.1
8.0
29
71
A79
ICPC
Malignancy NOS
3.0
7.9
42
140
HA1RA
NOMESCO Finland
Combined assessment of mammary gland (mammography and ultrasound)
2.3
7.9
67
290
HA1DA
NOMESCO Finland
Restricted mammography
9.4
7.8
15
16
SPAT1269
SPAT
Other puncture and/or drainage
4.0
7.7
29
73
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
3.5
7.7
34
99
SPAT1153
SPAT
Removal of sutures
1.3
7.6
800
6655
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
6.2
7.5
19
31
D50.1
ICD-10 Finland
Sideropenic dysphagia
13.4
7.4
12
9
QBE35
NOMESCO Finland
Repair of skin defect in trunk after surgery or injury
8.4
7.3
15
18
ZSZ10
NOMESCO Finland
Secondary repair operation
9.4
7.3
14
15
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
7.2
593
4763
QBA00
NOMESCO Finland
Puncture of skin of trunk
4.6
7.2
23
50
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
2.8
7.2
42
149
C50.80
ICD-10 Finland
Overall malignant tumor of the mammary gland, no histological veryfication
3.6
7.2
30
84
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
7.1
209
1389
SPAT1152
SPAT
Removal of foreign body from under the skin
2.1
7.1
75
361
ZXD20
NOMESCO Finland
Day surgery
1.4
7.1
335
2465
Y83.4
ICD-10 Finland
Other reconstructive surgery as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.0
7.0
16
23
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
13.8
6.9
11
8
ZX070
NOMESCO Finland
Intensity modified radiotherapy
2.7
6.8
42
155
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
3.1
6.8
35
115
ZZR30
NOMESCO Finland
Flap of muscle
5.7
6.7
18
32
PG1BD
NOMESCO Finland
Extensive CT angiography of tissue graft, e.g. assessment of TRAN graft
12.3
6.6
11
9
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.7
6.6
204
2868
C50.12
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,lobular tumor
3.7
6.6
26
70
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
6.5
214
1462
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.6
6.5
147
920
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
2.9
6.4
35
120
PD2BD
NOMESCO Finland
Extensive CT angiography of pelvic organs
70.0
6.4
7
*
ZZS50
NOMESCO Finland
Insertion of tissue expander
26.7
6.2
8
*
TQW40
NOMESCO Finland
Remowal of suture of skin
1.5
6.2
178
1181
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.0
6.2
69
344
WF002
NOMESCO Finland
Radical radiotherapy
2.0
6.1
68
337

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_BREAST_INTRADUCTAL – Carcinoma in situ of breast, intraductal

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).