Benign neoplasm: Pineal gland

CD2_BENIGN_PINEAL

adenoma: The congenital absence of the thyroid gland.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D35.4& Hospital discharge: ICD-9 — 2274 Hospital discharge: ICD-8 — 2263 Cause of death: ICD-10 — D35.4& Cause of death: ICD-9 — 2274 Cause of death: ICD-8 — 2263 2 out of 7 registries used, show all original rules.	88
4. Check minimum number of events None	88
5. Include endpoints None	88
6. Filter based on genotype QC (FinnGen only)	85

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D35
Name in latin: Neoplasma benignum corporis pinealis

NAME	CD2_BENIGN_PINEAL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D354
HD_ICD_9	2274
HD_ICD_8	2263
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D354
COD_ICD_9	2274
COD_ICD_8	2263
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Pineal gland based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	487	326	160
Only index persons	454	312	142
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	32.24	32.69	31.22
Only index persons	31.98	31.98	31.98

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	85	66	19
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	36.67	35.32	41.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
88: Matched controls
880

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D35.4

ICD-10 Finland

Benign neoplasm: Pineal gland

+∞

118.7

G93.0

ICD-10 Finland

Cerebral cysts

+∞

11.7

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

6.0

10.7

R51.80

ICD-10 Finland

Headache

3.8

8.0

125

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

4.7

7.8

AAB00

NOMESCO Finland

Extirpation of intracranial lesion

33.0

7.3

AA1AD

NOMESCO Finland

CT of head and brain

3.5

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3013707) Erythrocyte sedimentation rate by Westergren method

527

2.80

3.69

3.5

3.6

7.52

8.56

mm/h

0.46

487

(3016018) Differential panel - Cerebral spinal fluid

10.60

3.55

1.0

1.5

—

(3014007) Fractional oxyhemoglobin in Arterial blood

6.16

3.42

7.1

8.3

91.66

94.91

—

(3044290) Cell count panel - Cerebral spinal fluid

6.16

3.42

1.0

1.4

—

(3023410) Appearance of Cerebral spinal fluid

9.08

3.31

1.0

1.4

—

(3035637) Corticotropin [Mass/volume] in Plasma

7.94

3.10

1.0

1.9

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

152

2.24

2.86

1.9

1.8

0.64

0.65

mg/l

0.02

112

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

4.29

2.64

1.4

1.1

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

4.65

2.53

7.9

7.2

2.11

1.19

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

4.65

2.53

7.7

7.2

0.91

0.74

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

193

2.03

2.46

3.5

2.6

249.33

13.80

ng/l

0.47

(3013512) EKG study

145

2.13

2.45

3.0

2.9

—

(3019225) pH of Specimen

2.74

2.30

2.0

5.3

—

(3043409) Potassium [Moles/volume] in Arterial blood

5.22

2.10

10.8

2.5

3.86

4.13

mmol/l

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

4.21

2.07

1.7

6.8

24.93

24.51

mmol/l

—

(3022217) INR in Platelet poor plasma by Coagulation assay

224

1.84

1.96

4.1

8.1

1.03

1.10

inr

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

4.35

1.85

1.0

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

571

1.97

1.83

5.0

4.1

14.64

14.45

pmol/l

0.26

526

(3018405) Lactate [Moles/volume] in Arterial blood

4.01

1.74

11.0

2.8

1.36

1.65

mmol/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

684

2.24

1.61

5.8

4.6

1.60

1.70

mu/l

0.40

639

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

3.25

1.46

1.4

1.9

8.42

7.63

mmol/l

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

3.25

1.46

1.0

1.5

8.10

6.78

mmol/l

—

(3003396) Base excess in Arterial blood by calculation

2.39

1.45

8.9

5.1

1.50

mmol/l

—

(3020891) Body temperature

3.05

1.38

10.8

2.6

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

683

2.02

1.36

11.6

8.3

93.19

96.20

ml/min/173m2

0.53

546

(3019060) Gas panel - Arterial blood

2.61

1.33

10.7

3.6

—

(4034850) Laboratory test

2.88

1.30

4.4

14.8

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.88

1.30

1.4

1.3

—

(3000991) Gas panel - Venous blood

2.50

1.26

2.3

5.9

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.28

1.25

1.6

1.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

178

1.65

1.25

1.2

1.4

2.23

2.21

g/l

0.02

107

(3002256) Pathology report gross observation

1.89

1.21

1.1

—

(3048689) Calprotectin [Mass/mass] in Stool

120

1.74

1.21

3.2

2.1

112.86

77.55

ug/g

0.27

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

171

1.65

1.20

1.8

1.9

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.46

1.10

1.8

4.9

134.00

132.57

g/l

—

(3022621) pH of Urine by Test strip

2.02

1.06

3.1

2.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

221

1.54

1.05

1.4

1.6

103.19

96.52

pmol/l

0.20

122

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.93

1.02

7.1

4.7

105.44

104.08

mmol/l

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

104

0.45

0.96

1.8

1.6

—

(3012544) pH of Venous blood

1.97

0.96

1.9

4.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

216

1.51

0.96

3.4

2.7

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.07

0.89

1.8

2.9

3.97

4.49

kpa

—

(40768804) Tissue Pathology biopsy report

286

1.44

0.86

2.0

1.8

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

664

1.58

0.83

3.7

3.4

5.55

5.65

mmol/l

0.37

616

(3019832) Treponema pallidum Ab [Presence] in Serum

215

0.64

0.81

1.5

1.8

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.88

0.80

1.8

1.4

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.80

0.0

1.2

—

2.75

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.80

0.0

1.1

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

506

1.43

0.80

7.4

6.9

72.96

72.64

u/l

0.03

471

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

152

1.50

0.79

1.9

1.8

2.14

2.73

mg/l

1.26

129

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.78

0.78

8.1

6.8

1.05

1.03

mmol/l

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

188

1.46

0.78

3.5

3.6

2.39

2.35

mmol/l

1.02

169

(3045414) Leukocytes [Presence] in Urine

2.24

0.77

2.0

1.3

—

(3044889) 12 lead EKG panel

428

1.39

0.75

2.8

2.7

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.98

0.72

1.0

1.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.90

0.69

1.2

1.9

—

(4035726) Immunohistochemistry procedure

1.68

0.68

1.0

1.4

—

(40768443) Skin Pathology biopsy report

1.83

0.67

1.4

1.1

—

(40768797) Stomach Pathology biopsy report

1.60

0.66

1.1

1.3

—

(3023368) Bacteria identified in Blood by Culture

123

1.47

0.64

4.2

3.7

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.66

0.63

1.0

1.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

124

1.46

0.61

1.5

1.6

—

(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.60

0.0

1.2

—

1.50

—

(3044640) Blood type and Crossmatch panel - Blood

225

1.36

0.60

1.9

2.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

236

1.34

0.57

2.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

100

1.48

0.56

1.1

1.6

452.07

496.29

pmol/l

0.18

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.62

0.55

2.0

4.0

5.78

5.72

kpa

—

(40761535) Cells panel - Urine sediment

1.57

0.50

2.6

2.9

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.53

0.49

3.5

2.7

35.00

26.47

u/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.45

0.49

2.2

1.8

—

(3021601) Nitrite [Presence] in Urine by Test strip

357

1.28

0.49

6.3

4.4

0.00

estimate

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

208

1.28

0.41

1.2

1.3

0.61

1.16

u/ml

—

(3018095) Leukocytes [#/volume] in Urine

246

1.27

0.41

4.2

2.9

151.32

34.04

e6/l

0.50

162

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.41

0.0

1.2

—

(3009261) Glucose [Presence] in Urine by Test strip

363

1.24

0.41

5.3

3.2

0.00

estimate

—

(36660697) Celiac disease serology panel - Serum

1.43

0.41

1.1

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.40

0.0

2.2

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.40

0.0

1.2

—

95.94

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

423

1.24

0.40

8.7

9.5

4.34

3.97

e9/l

0.62

377

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.39

0.0

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.34

0.38

7.1

5.5

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.41

0.38

1.7

2.5

9805.84

4828.50

u/l

—

(3031040) Bacteria [#/volume] in Urine by Automated count

494

0.82

0.37

6.9

3.8

—

38.00

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.42

0.36

6.3

2.5

1.22

1.23

mmol/l

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.39

0.35

1.2

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

242

1.23

0.34

1.2

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

138

1.29

0.33

1.2

1.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

214

1.23

0.33

2.0

2.1

—

(3003694) ABO and Rh group [Type] in Blood

277

0.82

0.31

1.6

1.7

—

(3018418) pH of Serum or Plasma

168

1.25

0.30

3.9

2.8

7.39

7.41

—

(1761868) Lipid panel - Serum or Plasma

276

0.82

0.30

2.6

2.1

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.32

0.29

2.1

—

(40761536) Microorganisms panel - Urine sediment

1.23

0.27

9.2

3.3

—

(36304419) Bacteria [Presence] in Urine

180

1.22

0.27

3.5

2.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.32

0.25

1.1

1.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

106

1.27

0.25

2.9

2.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

357

1.17

0.24

2.4

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

135

0.79

0.24

1.4

1.5

—

(3028707) Methadone [Presence] in Urine by Screen method

1.26

0.23

1.6

2.0

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

136

1.22

0.22

1.8

2.0

—

(3021589) Normoblasts [#/volume] in Blood

330

0.86

0.22

13.5

7.1

0.00

e9/l

0.50

270

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.4

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

111

0.79

0.21

2.0

1.9

—

(21494755) Public health laboratory ask at order entry panel

114

0.77

0.21

1.3

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

1.29

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

10.75

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.00

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

40.35

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.00

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.2

—

0.00

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.24

0.20

3.0

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.20

0.0

2.2

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.1

—

2.61

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.1

—

6.85

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.1

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.1

—

2.54

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.20

0.0

1.0

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.1

—

3.53

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.20

0.0

1.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.22

0.19

1.6

1.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.20

0.18

1.9

1.6

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.18

0.18

1.0

—

(3012516) Albumin [Mass/volume] in Urine

130

1.19

0.17

7.7

3.1

100.18

73.34

mg/l

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.14

0.16

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.14

0.16

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.14

0.16

1.4

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.17

0.16

3.6

2.3

3.67

6.40

umol/l

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.17

0.16

1.4

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

160

1.16

0.15

5.1

3.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

209

1.14

0.15

1.8

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

688

0.89

0.12

4.1

3.3

1.59

1.49

mmol/l

0.72

650

(3026008) Bacteria identified in Urine by Culture

202

1.12

0.12

4.3

2.3

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

653

1.11

0.10

3.6

3.0

1.43

1.23

mmol/l

1.41

612

(3023511) Choriogonadotropin [Units/volume] in Urine

1.17

0.10

1.6

1.3

—

(4200892) Spirometry reversibility

1.07

0.09

1.2

1.3

—

(40758558) Short blood count panel - Blood

175

1.11

0.09

9.4

7.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

136

1.12

0.09

8.7

3.5

34.07

9.89

mg/mmol

—

(3029937) Albumin [Presence] in Urine by Test strip

195

1.10

0.09

7.0

3.4

0.00

estimate

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.06

0.09

2.8

1.8

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.79

0.08

1.6

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

334

1.08

0.08

8.0

6.8

—

(3000494) Fungus identified in Specimen by Culture

1.08

0.08

1.4

1.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.08

0.08

1.1

1.2

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.07

0.08

1.6

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.11

0.08

1.1

1.3

—

(3016879) Cocaine [Presence] in Urine

1.11

0.08

1.5

1.7

—

(3027008) Opiates [Presence] in Urine

1.06

0.07

1.6

1.7

—

(3027944) Amphetamines [Presence] in Urine

1.06

0.07

1.7

—

(3000764) Benzodiazepines [Presence] in Urine

1.06

0.07

1.6

1.7

—

(3028300) Cannabinoids [Presence] in Urine

1.06

0.07

1.6

1.7

—

(3042936) Bacteria identified in Isolate by Culture

1.09

0.07

1.4

2.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

697

1.10

0.07

4.1

3.5

2.82

2.84

mmol/l

0.05

658

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

658

1.08

0.06

4.2

3.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

240

1.06

0.04

2.4

1.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

281

1.05

0.03

5.6

3.1

—

(3035350) Ketones [Presence] in Urine by Test strip

361

1.04

0.03

5.4

3.1

0.00

estimate

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

132

0.98

0.00

1.2

2.24

5.63

u/ml

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

302

0.99

0.00

1.5

2.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

215

1.03

0.00

4.6

2.7

—

(3002385) Erythrocyte distribution width [Ratio]

666

1.03

0.00

17.2

12.5

14.07

14.29

0.15

660

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

694

0.97

0.00

4.0

3.3

4.86

4.72

mmol/l

0.63

655

(3037467) Urinalysis macro (dipstick) panel - Urine

516

1.02

0.00

5.9

4.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.94

0.00

1.4

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

1.4

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

-0.00

0.0

1.0

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

106.13

—

(3034426) Prothrombin time (PT)

0.00

-0.00

0.0

1.3

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.5

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

0.40

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.2

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

3.1

—

92.57

—

(3015183) Erythrocyte sedimentation rate

0.00

-0.00

0.0

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

60.71

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.7

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

5.38

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

818.40

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3030558) Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

3.95

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.2

—

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.8

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.3

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.98

-0.00

1.4

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.4

—

5.30

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

-0.00

0.0

1.0

—

13.25

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.5

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.93

-0.00

1.7

1.5

—

(3005033) Fetal Nuchal fold Thickness US

0.97

-0.00

1.5

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

56.00

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.4

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3005322) IgE [Units/volume] in Serum or Plasma

0.84

-0.00

1.4

1.2

103.00

553.67

u/ml

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

3.1

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

-0.00

0.0

1.0

—

104.00

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

106.90

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3022145) Colonoscopy Study observation

0.95

-0.00

1.5

1.4

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.29

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

1.3

—

47.08

—

(3010503) CD19 cells [#/volume] in Blood

0.00

-0.00

0.0

1.0

—

0.20

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

1.3

—

687.00

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

-0.00

0.0

1.0

—

(3011288) Drugs identified in Urine by Screen method

0.92

-0.00

1.4

2.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_PINEAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_PINEAL.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_PINEAL – Benign neoplasm: Pineal gland

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Pineal gland

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints