≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Complications following abortion and ectopic and molar pregnancy

EFO MESH Endpoint Browser PheWeb

O15_COMPLIC_ABORT_ECTOP_MOLAR

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O08
  • Hospital discharge: ICD-9 — 639
  • Hospital discharge: ICD-8 — 6459[015]
  • Cause of death: ICD-10 — O08
  • Cause of death: ICD-9 — 639
  • Cause of death: ICD-8 — 6459[015]

2 out of 7 registries used, show all original rules.

1301

4. Check minimum number of events

None

1301

5. Include endpoints

None

1301

6. Filter based on genotype QC (FinnGen only)

1301

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O00-O08
Name in latin
Complicationes abortus, graviditatis extrauterinae et molae hydatidosae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8768 8768 -
Only index persons 8294 8294 -
Unadjusted period prevalence (%)
Whole population 0.25 0.25 -
Only index persons 0.30 0.30 -
Median age at first event (years)
Whole population - 27.90 -
Only index persons - 27.76 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1301 1301 -
Unadjusted period prevalence (%) 0.44 0.44 -
Median age at first event (years) 27.22 27.22 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1189
Matched controls
11889
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
64595
ICD-8 Finland
Other abortion, Haemorrhagia post abortum NUD
+∞
323.0
474
*
64591
ICD-8 Finland
Other abortion, Endometritis post abortum
+∞
323.0
341
*
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
253.4
234
*
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
152.4
143
*
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
136.1
128
*
O02.1
ICD-10 Finland
Missed abortion
+∞
120.9
114
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
120.9
114
*
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1257.9
118.9
114
*
O08.0
ICD-10 Finland
Genital tract and pelvic infection following abortion and ectopic and molar pregnancy
+∞
116.6
110
*
8502
FHL
Evacuation and abrasion
44.8
89.1
110
27
8511
FHL
Cervical dilation and drainage with suction
431.0
82.0
81
*
6391A
ICD-9 Finland
Complications following abortion and ectopic and molar pregnancies, Delayed or excessive haemorrhage
+∞
73.7
70
*
64590
ICD-8 Finland
Other abortion, Salpingo-oophoritis post abortum
+∞
70.5
67
*
O08.1
ICD-10 Finland
Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy
+∞
68.4
65
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
64.1
61
*
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
57.8
55
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
17.7
54.2
86
52
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
260.6
49.4
50
*
64190
ICD-8 Finland
Artificial termination of pregnancy performed on the basis of another legal reason, Humanitarian reason
+∞
49.3
47
*
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
497.3
48.7
48
*
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
41.9
40
*
6370A
ICD-9 Finland
Unspecified abortion, Complicated by genital tract and pelvic infection
+∞
39.8
38
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
45.3
39.3
48
11
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
206.7
39.1
40
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
53.1
38.8
46
9
64099
ICD-8 Finland
Abortion induced for medical indications, Without mention of sepsis or toxaemia
+∞
36.6
35
*
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
+∞
35.6
34
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
+∞
33.5
32
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
49.0
31.7
38
8
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
+∞
29.3
28
*
LCH11
NOMESCO Finland
Pharmacologic abortion
58.2
29.2
34
6
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
4.7
28.3
100
227
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
28.2
27
*
64598
ICD-8 Finland
Other abortion
+∞
27.2
26
*
8501
FHL
Emptying the uterus with suction
95.5
25.7
28
*
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
4.5
23.0
85
202
O08.8
ICD-10 Finland
Other complications following abortion and ectopic and molar pregnancy
+∞
23.0
22
*
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
+∞
23.0
22
*
P01AB01
ATC
metronidazole; oral, rectal
1.8
22.4
571
3969
64090
ICD-8 Finland
Artificial termination of pregnancy performed for medical reasons, Woman's illness or physical defect (medicines. Cause)
+∞
21.9
21
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
78.2
20.7
23
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
19.8
19
*
6392A
ICD-9 Finland
Complications following abortion and ectopic and molar pregnancies, Damage to pelvic organs and tissues
+∞
19.8
19
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
18.8
18
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
17.2
305
1829
O20.0
ICD-10 Finland
Threatened abortion
8.5
15.8
34
41
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
15.7
15
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.6
15.1
117
482
J01DA01
ATC
[U] cefalexin; systemic
1.6
14.7
757
6142
63150
ICD-8 Finland
Ectopic pregnancy, Tubaria rupta, sepsi non indicata
+∞
14.6
14
*
64593
ICD-8 Finland
Other abortion, Abortus inhibitus, cum abortu
+∞
14.6
14
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.3
14.6
75
239
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
14.1
382
2596
MBA05
NOMESCO Finland
Curettage of uterus after abortion
141.5
13.5
14
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
13.3
474
3459
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
12.3
13.1
23
19
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.1
12.9
70
232
XLA10
NOMESCO Finland
NA
2.6
12.6
96
392
8512
FHL
Cervical dilatation and other surgical evacuation
+∞
12.5
12
*
6331A
ICD-9 Finland
Ectopic pregnancy, Tubal pregnancy
+∞
12.5
12
*
M54.5
ICD-10 Finland
Low back pain
1.6
12.5
396
2792
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
11.9
467
3467
R03AC02
ATC
salbutamol; inhalant
1.5
11.5
643
5169
6350D
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORT PROV LEGAL SINE COMPL,ÄIDIN IKÄ <17 V TAI >40]
+∞
11.5
11
*
MBW96
NOMESCO Finland
Other operation after delivery or abortion
+∞
11.5
11
*
R51.80
ICD-10 Finland
Headache
1.9
11.1
182
1047
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.3
11.0
100
450
Y6099
ICD-8 Finland
Prenatal care and observation
2.3
10.8
102
467
ZXD05
NOMESCO Finland
Urgent procedure
1.6
10.8
315
2156
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
4.0
10.7
41
104
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.8
10.6
68
253
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
10.6
155
852
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
3.2
10.6
54
173
28000
ICD-8 Finland
Iron deficiency anaemias, Posthaemorrhagica
9.3
10.5
21
23
8509
FHL
Other measure in this category
110.9
10.4
11
*
64300
ICD-8 Finland
Spontaneous abortion, With sepsis
+∞
10.4
10
*
O08.6
ICD-10 Finland
Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy
+∞
10.4
10
*
63151
ICD-8 Finland
Ectopic pregnancy, Tubaria NUD sepsi non indicata
+∞
10.4
10
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
10.3
142
767
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.9
10.2
161
911
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
10.2
201
1228
M03BX02
ATC
tizanidine; oral
1.5
10.1
763
6467
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
10.1
397
2920
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
9.9
482
3712
SPAT1312
SPAT
General health counselling
1.5
9.7
361
2612
X58
ICD-10 Finland
Exposure to other specified factors
1.9
9.7
142
784
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
9.5
71
290
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.5
416
3122
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
+∞
9.4
9
*
6398X
ICD-9 Finland
Complications following abortion and ectopic and molar pregnancies, Other specified complications following abortion or ectopic and molar pregnancy
+∞
9.4
9
*
6341A
ICD-9 Finland
NA
+∞
9.4
9
*
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
9.4
9
*
O08.9
ICD-10 Finland
Complication following abortion and ectopic and molar pregnancy, unspecified
+∞
9.4
9
*
R06.0
ICD-10 Finland
Dyspnoea
1.6
9.4
265
1792
8113
FHL
Fractional scraping
2.0
9.4
121
638
XMA22
NOMESCO Finland
General examination of pregnant woman
2.7
9.0
58
218
62202
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Endometritis NUD
24.2
8.9
12
5
62650
ICD-8 Finland
Disorders of menstruation, Irregular
4.8
8.8
28
60
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.8
364
2692
62200
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Endometritis acuta
7.2
8.7
20
28
1410
FHL
Laparoscopy
2.7
8.7
59
229
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
8.6
160
958
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.6
519
4143
SPAT1263
SPAT
Sampling
1.5
8.5
467
3655
J01AA02
ATC
doxycycline; systemic
1.5
8.5
942
8479
M01AB05
ATC
diclofenac; systemic, rectal
1.5
8.4
786
6817
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
8.3
8
*
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
8.3
8
*
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.4
8.3
500
3980
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
8.3
162
986
H25.8
ICD-10 Finland
Other senile cataract
2.0
8.3
108
570
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
1.7
8.2
171
1059
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
8.2
61
250
1412
FHL
Laparoscopy and sterilization
1.8
8.2
139
806
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.9
8.1
111
599
8115
FHL
Laparoscenes (including Douglas)
17.3
8.1
12
7
R42
ICD-10 Finland
Dizziness and giddiness
1.6
8.1
239
1628
J01FA06
ATC
roxithromycin; oral
1.4
8.0
483
3836
A02BC02
ATC
pantoprazole; systemic
1.4
8.0
756
6533
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.6
8.0
58
233
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.0
804
7033
AA1AD
NOMESCO Finland
CT of head and brain
1.6
8.0
235
1598
L03
ICPC
Low back symptom/complaint
1.5
8.0
289
2066
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
2.5
7.8
58
237
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.8
584
4821
6289B
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD SEC]
10.9
7.8
14
13
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
4.9
7.8
24
50
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.8
157
961
M25.5
ICD-10 Finland
Pain in joint
1.5
7.8
345
2576
00000
ICD-8 Finland
NA
4.4
7.7
26
60
N03AX12
ATC
gabapentin; oral
1.7
7.6
184
1187
SPAT1216
SPAT
Assessment of functional ability
1.7
7.4
165
1042
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
7.4
137
817
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.5
7.4
54
218
63110
ICD-8 Finland
Ectopic pregnancy, Tubaria rupta, cum sepsi
+∞
7.3
7
*
6339X
ICD-9 Finland
Ectopic pregnancy, Unspecified ectopic pregnancy
+∞
7.3
7
*
J20
ICD-10 Finland
Acute bronchitis
1.8
7.2
117
667
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
7.2
271
1946
6140A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Acute salpingitis and oophoritis[S-O-ITIS ACUTA]
4.9
7.2
22
46
G02CB01
ATC
bromocriptine; systemic
3.6
7.0
29
81
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.1
7.0
73
352
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
6.9
115
664
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.9
193
1293
C07AA05
ATC
propranolol; systemic
1.5
6.9
233
1632
63460
ICD-8 Finland
Other complications of pregnancy, Habitual aborter, undelivered
11.0
6.8
12
11
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.8
435
3467
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.8
390
3047
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
4.3
6.7
23
54
R52.2
ICD-10 Finland
Other chronic pain
2.7
6.7
43
161
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
6.7
172
1128
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
6.7
340
2598
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.2
6.6
23
55
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
5.5
6.6
18
33
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
6.6
303
2265
WX110
NOMESCO Finland
Local anesthesy
1.4
6.6
762
6702
N05BA12
ATC
alprazolam; oral
1.7
6.5
128
778
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.1
6.5
72
356
M02AA07
ATC
piroxicam; topical
1.4
6.5
433
3471
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
70.2
6.4
7
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
6.4
196
1339
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
2.1
6.4
65
313
Y0609
ICD-8 Finland
Examination of the urinary and genital organs, Genital organs
3.2
6.4
31
99
Z87.4
ICD-10 Finland
Personal history of diseases of the genitourinary system
4.9
6.4
19
39
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.3
123
744
L28
ICPC
Limited function/disability (L)
1.6
6.3
165
1088
M75
ICD-10 Finland
Shoulder lesions
2.3
6.3
54
240
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.0
6.3
71
358
64510
ICD-8 Finland
NA
+∞
6.3
6
*
O04.3
ICD-10 Finland
Medical abortion, incomplete, with other and unspecified complications
+∞
6.3
6
*
8519
FHL
Other measure in this category
+∞
6.3
6
*
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
3.5
6.2
27
79
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
6.2
171
1141
S99.9
ICD-10 Finland
Unspecified injury of ankle and foot
4.0
6.2
23
59
A04
ICPC
Weakness/tiredness general
1.7
6.2
133
832
M54
ICD-10 Finland
Dorsalgia
1.7
6.1
121
736
N83.1
ICD-10 Finland
Corpus luteum cyst
3.9
6.1
23
60
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.2
6.1
55
251
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.1
415
3332
M79.6
ICD-10 Finland
Pain in limb
1.4
6.0
409
3273

Mortality – FinRegistry

↥

Association

Association between endpoint O15_COMPLIC_ABORT_ECTOP_MOLAR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_COMPLIC_ABORT_ECTOP_MOLAR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: O15_COMPLIC_ABORT_ECTOP_MOLAR – Complications following abortion and ectopic and molar pregnancy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data