No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
84548 |
4. Check minimum number of eventsNone |
84548 |
5. Include endpoints |
85923 |
6. Filter based on genotype QC (FinnGen only) |
85923 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF5
Pregnancy with abortive outcome
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 665419 | 665419 | - |
| Only index persons | 640469 | 640469 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 19.06 | 19.06 | - |
| Only index persons | 23.55 | 23.55 | - |
| Median age at first event (years) | |||
| Whole population | - | 27.25 | - |
| Only index persons | - | 27.16 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 85923 | 85923 | - |
| Unadjusted period prevalence (%) | 29.29 | 29.29 | - |
| Median age at first event (years) | 27.54 | 27.54 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4231
- Matched controls
- 28893
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1392.4
323.0
942
6
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
323.0
387
*
LCH11
NOMESCO Finland
Pharmacologic abortion
520.0
323.0
754
12
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
323.0
942
*
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
323.0
475
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
10.7
307.1
684
510
W79
ICPC
Unwanted pregnancy
61.5
301.5
400
49
64099
ICD-8 Finland
Abortion induced for medical indications, Without mention of sepsis or toxaemia
+∞
287.9
317
*
64090
ICD-8 Finland
Artificial termination of pregnancy performed for medical reasons, Woman's illness or physical defect (medicines. Cause)
+∞
258.4
285
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
7.6
244.7
669
699
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
62.8
183.4
243
28
O02.1
ICD-10 Finland
Missed abortion
655.8
161.8
184
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
62.5
157.6
209
24
W78
ICPC
Pregnancy
3.6
141.5
790
1753
W83
ICPC
Abortion induced
216.4
128.3
152
5
SPAT1371
SPAT
Assessment of need for induced abortion
121.2
124.9
154
9
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
123.3
137
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
113.3
126
*
SPAT1379
SPAT
Health check-up of pregnant person
3.3
109.8
661
1528
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
3.9
107.5
521
1009
64190
ICD-8 Finland
Artificial termination of pregnancy performed on the basis of another legal reason, Humanitarian reason
+∞
95.2
106
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
11.2
90.0
191
121
SPAT1197
SPAT
Extensive health check-up of expecting family
3.1
84.3
556
1356
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
2.9
82.3
584
1496
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.1
81.9
1227
4673
SPAT1380
SPAT
Postpartum check-up
3.1
75.3
473
1111
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.5
71.0
380
789
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.7
69.8
350
688
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.6
69.7
593
1688
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
146.2
69.2
84
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
3.0
67.6
461
1140
O04
ICD-10 Finland
Medical abortion
139.1
65.7
80
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
3.1
62.2
396
933
64598
ICD-8 Finland
Other abortion
+∞
61.9
69
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
125.0
58.7
72
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
463.9
58.3
67
*
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
56.5
63
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
3.3
55.1
311
670
WX307
NOMESCO Finland
Obstetric epidural analgesia
3.3
53.6
306
664
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.7
52.2
419
1142
64094
ICD-8 Finland
NA
+∞
52.0
58
*
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
5.1
51.9
182
251
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
3.7
50.9
251
484
W01
ICPC
Question of pregnancy
6.4
50.3
147
161
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
49.3
55
*
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.2
47.9
281
622
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
47.5
53
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
+∞
46.6
52
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
3.4
46.1
253
532
64595
ICD-8 Finland
Other abortion, Haemorrhagia post abortum NUD
+∞
45.7
51
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
44.8
50
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
7.7
44.1
113
102
MAX99
NOMESCO Finland
Assistance to normal delivery
3.4
43.2
232
480
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.9
42.5
193
346
Z37.0
ICD-10 Finland
Single live birth
3.9
41.4
192
351
MA3AE
NOMESCO Finland
Combined first trimester screening
3.0
41.2
267
631
Z3232
NOMESCO Finland
Midwife
3.5
41.0
213
429
WZB00
SPAT
NA
0.4
40.9
208
3223
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
115.1
40.6
50
*
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
+∞
40.3
45
*
63150
ICD-8 Finland
Ectopic pregnancy, Tubaria rupta, sepsi non indicata
+∞
38.5
43
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
37.4
1310
6281
SPAT1372
SPAT
Follow-up examination after induced abortion
295.4
36.9
43
*
Z34
ICD-10 Finland
Supervision of normal pregnancy
4.6
35.2
136
209
64300
ICD-8 Finland
Spontaneous abortion, With sepsis
+∞
34.9
39
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.8
34.4
241
601
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.9
34.3
154
274
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.3
34.0
105
1999
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
33.3
965
4373
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.7
33.1
254
671
O04.4
ICD-10 Finland
Medical abortion, incomplete, without complication
+∞
32.2
36
*
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
12.4
30.8
61
34
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
+∞
30.4
34
*
W90
ICPC
Uncompl labour/delivery livebirth
3.0
30.1
193
454
O20.0
ICD-10 Finland
Threatened abortion
15.4
27.1
49
22
OAA11
SPAT
NA
2.9
26.6
177
427
SPAT1196
SPAT
Monitoring of normal pregnancy
5.4
26.0
85
109
N02BE01
ATC
paracetamol; systemic, rectal
1.6
25.9
3497
21771
W82
ICPC
Abortion spontaneous
19.8
25.9
43
15
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
207.4
25.4
30
*
W29
ICPC
Pregnancy symptom/complaint other
4.0
25.0
110
193
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
24.4
25.0
39
11
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.0
24.8
159
375
D10
ICPC
Vomiting
2.0
23.9
353
1274
O99.80
ICD-10 Finland
The fear of childbirth
3.3
23.6
130
274
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.3
23.6
130
274
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
5.7
23.2
72
87
W84
ICPC
Pregnancy high risk
3.2
22.6
131
287
Y4301
ICD-8 Finland
Preventive sterilization, Legal sterilization, medico-social reasons (weakness)
5.2
22.2
74
98
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.8
22.1
419
1654
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
178.9
21.9
26
*
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.9
21.9
96
169
KAY40
NOMESCO Finland
NA
0.3
21.5
46
1040
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.8
20.9
147
368
64093
ICD-8 Finland
Artificial termination of pregnancy performed for a medical reason, Other medical reason
+∞
20.6
23
*
KAY20
NOMESCO Finland
NA
0.3
20.2
35
879
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.5
19.7
164
455
O04.5
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by genital tract and pelvic infection
+∞
19.7
22
*
O04.3
ICD-10 Finland
Medical abortion, incomplete, with other and unspecified complications
+∞
19.7
22
*
64593
ICD-8 Finland
Other abortion, Abortus inhibitus, cum abortu
+∞
19.7
22
*
ZYC02
SPAT
NA
0.4
19.6
71
1270
OAB39
SPAT
NA
0.4
19.4
98
1536
W85
ICPC
Gestational diabetes
3.0
18.8
117
272
63151
ICD-8 Finland
Ectopic pregnancy, Tubaria NUD sepsi non indicata
+∞
18.8
21
*
64591
ICD-8 Finland
Other abortion, Endometritis post abortum
+∞
18.8
21
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
18.2
1462
8036
64499
ICD-8 Finland
Abortion not specified as induced or spontaneous, Without mention of sepsis or toxaemia
+∞
17.9
20
*
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
9.6
17.8
39
28
O21
ICD-10 Finland
Excessive vomiting in pregnancy
4.9
17.3
60
84
LCH25
SPAT
NA
+∞
17.0
19
*
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
4.1
16.5
68
114
OAB42
SPAT
NA
0.5
16.5
158
2008
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.7
16.4
121
313
R2110
NOMESCO Finland
Giving the first information
2.0
16.4
231
817
-2
ICD-10 Finland
NA
0.3
15.6
46
897
N96
ICD-10 Finland
Habitual aborter
68.6
15.6
20
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.8
15.6
107
267
Z32
ICD-10 Finland
Pregnancy examination and test
8.2
15.6
37
31
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
4.1
15.5
64
108
T74.1
ICD-10 Finland
Physical abuse
3.5
15.3
76
151
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
15.2
17
*
TMA00
NOMESCO Finland
Episiotomy
4.5
15.1
56
85
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
3.4
14.8
76
155
J01CA08
ATC
pivmecillinam; oral
1.3
14.7
2326
13991
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
4.1
14.4
59
99
SPAT1187
SPAT
General ultrasound examination in early pregnancy
7.8
14.3
35
31
W27
ICPC
Fear of complications of pregnancy
7.1
14.2
37
36
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.9
14.2
91
218
04300
ICD-8 Finland
NA
13.7
14.1
26
13
W05
ICPC
Pregnancy vomiting/nausea
3.9
14.1
61
108
SPAT1364
SPAT
Health check-up performed during second study year in students of upper secondary schools, vocational schools etc.
0.6
13.9
305
3161
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
4.8
13.7
48
69
W03
ICPC
Antepartum bleeding
7.5
13.7
34
31
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.8
13.4
239
924
Z51.2
ICD-10 Finland
Other chemotherapy
+∞
13.4
15
*
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
+∞
13.4
15
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
13.4
1210
6702
M54.5
ICD-10 Finland
Low back pain
1.3
13.2
1188
6570
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
4.5
13.2
49
75
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.8
13.0
58
106
SPAT1195
SPAT
Antenatal classes
3.0
13.0
79
183
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
12.8
1798
10560
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.8
12.8
85
208
J01AA02
ATC
doxycycline; systemic
1.3
12.6
2421
14788
SPAT1272
SPAT
Drug screening
10.5
12.6
26
17
O81.4
ICD-10 Finland
Vacuum extractor delivery
2.7
12.6
88
223
ZXE00
NOMESCO Finland
One hour or less
1.3
12.5
1338
7570
O04.8
ICD-10 Finland
Medical abortion, complete or unspecified, with other and unspecified complications
+∞
12.5
14
*
SPAT1200
SPAT
Guidance for breast-feeding and breast care
2.7
12.4
91
237
X92
ICPC
Chlamydia infection genital female
2.0
12.4
168
587
OAB36
SPAT
NA
0.3
12.4
24
567
SPAT1315
SPAT
Periodic health check-up of children and adolescents
0.7
12.3
581
5239
W02
ICPC
Fear of pregnancy
2.8
12.2
84
211
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.5
12.2
60
119
MAE00
NOMESCO Finland
Outlet vacuum delivery
2.9
12.2
79
191
SPAT1357
SPAT
Monitoring of problem during pregnancy
6.7
12.0
32
33
D01
ICPC
Abdominal pain/cramps general
1.4
11.9
606
3041
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.1
11.9
144
482
WZC00
SPAT
NA
0.5
11.8
125
1546
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
11.8
1620
9462
ZXD05
NOMESCO Finland
Urgent procedure
1.3
11.7
999
5463
SAB02
NOMESCO Finland
Oral and dental health check by dental hygienist or dental assistant
0.7
11.7
371
3582
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
+∞
11.6
13
*
Z35.6
ICD-10 Finland
Supervision of very young primigravida
6.7
11.6
31
32
R51.80
ICD-10 Finland
Headache
1.4
11.5
618
3134
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.4
11.5
566
2825
P19
ICPC
Drug abuse
4.2
11.4
45
74
K04.08
ICD-10 Finland
Other specified pulpit
2.0
11.4
152
529
SGA01
NOMESCO Finland
Tooth opening as first aid
1.6
11.4
327
1453
J01DB01
ATC
cefalexin; oral
1.3
11.4
3061
19373
O03
ICD-10 Finland
Spontaneous abortion
9.7
11.2
24
17
K04.0
ICD-10 Finland
Pulpitis
1.8
11.2
209
822
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.9
11.2
47
82
D09
ICPC
Nausea
1.5
10.9
359
1646
Z2221
NOMESCO Finland
Medical doctor
1.3
10.7
908
4951
64510
ICD-8 Finland
NA
+∞
10.7
12
*
63199
ICD-8 Finland
Other or unspecified ectopic pregnancy, without mention of sepsis
+∞
10.7
12
*
O03.5
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by genital tract and pelvic infection
+∞
10.7
12
*
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
3.1
10.7
62
140
IHZ05
SPAT
NA
0.5
10.6
73
1024
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
6.6
10.5
28
29
OAA10
SPAT
NA
2.5
10.5
86
241
SPAT1283
SPAT
Restricted health certificate
1.3
10.3
815
4394
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
2.8
10.3
69
172
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
7.1
10.3
26
25
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.6
10.2
75
197
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
10.0
397
1898
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.9
10.0
157
584
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
4.3
10.0
38
61
XMA22
NOMESCO Finland
General examination of pregnant woman
3.4
9.9
49
99
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
9.9
829
4509
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
3.6
9.9
45
85
SPAT1316
SPAT
Extensive health check-up of children and adolescents
0.7
9.9
291
2852
O47.9
ICD-10 Finland
False labour, unspecified
3.3
9.8
51
107
N61
ICD-10 Finland
Inflammatory disorders of breast
2.6
9.8
73
194
R74
ICPC
Upper respiratory infection acute
1.3
9.8
1140
6481
IGY99
SPAT
NA
0.3
9.8
18
435
Z36.8
ICD-10 Finland
Other antenatal screening
3.4
9.7
48
97
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
3.0
9.7
57
131
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
9.6
520
2638
M03BX02
ATC
tizanidine; oral
1.2
9.5
1463
8593
U01
ICPC
Dysuria/painful urination
1.4
9.5
480
2405
U02
ICPC
Urinary frequency/urgency
1.3
9.5
756
4083
R03AC02
ATC
salbutamol; inhalant
1.2
9.3
1837
11088
A03
ICPC
Fever
1.3
9.2
687
3672
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
3.8
9.1
39
70
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.5
9.1
76
214
O05.9
ICD-10 Finland
Other abortion, complete or unspecified, without complication
+∞
8.9
10
*
WX402
NOMESCO Finland
General anaesthesia
1.4
8.9
390
1901
N76.0
ICD-10 Finland
Acute vaginitis
1.5
8.8
271
1224
Y6099
ICD-8 Finland
Prenatal care and observation
2.5
8.8
69
189
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
0.5
8.8
90
1121
Z39
ICD-10 Finland
Postpartum care and examination
5.9
8.8
25
29
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2.7
8.7
59
149
KAY60
NOMESCO Finland
NA
0.3
8.7
24
479
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
3.5
8.6
41
81
Z72.2
ICD-10 Finland
Drug use
6.1
8.6
24
27
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.7
8.6
58
146
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
2.4
8.6
76
222
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
3.4
8.6
42
85
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
8.5
1032
5879
N07BA03
ATC
varenicline; oral
3.1
8.5
47
103
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
2.9
8.4
52
123
ZYC05
SPAT
NA
0.4
8.4
28
515
Y4302
ICD-8 Finland
Preventive sterilization, Legal sterilization, social reasons
4.2
8.4
32
52
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
5.5
8.4
25
31
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.6
8.4
60
157
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
4.0
8.3
34
59
SPAT1366
SPAT
Health check-up performed based on health survey in students of universities, universities of applied sciences etc.
0.6
8.3
118
1350
OAA12
SPAT
NA
2.4
8.3
69
197
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
8.2
1512
9026
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
8.2
1284
7531
R05
ICPC
Cough
1.3
8.1
905
5101
Z71.8
ICD-10 Finland
Other specified counselling
1.3
8.1
929
5255
N97.9
ICD-10 Finland
Female infertility, unspecified
2.7
8.1
55
140
P02
ICPC
Acute stress reaction
1.8
8.0
151
597
M01AB05
ATC
diclofenac; systemic, rectal
1.2
8.0
1745
10583
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
8.0
613
3282
SPAT1192
SPAT
Gynaecological examination
1.4
8.0
504
2620
O03.8
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, with other and unspecified complications
68.4
8.0
10
*
O05
ICD-10 Finland
Other abortion
68.4
8.0
10
*
Z72.0
ICD-10 Finland
Tobacco use
2.9
7.9
49
116
QXA70
SPAT
NA
0.3
7.9
21
427
A02BC02
ATC
pantoprazole; systemic
1.2
7.9
2157
13372
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
7.9
646
3495
99450
ICD-8 Finland
Effects of other external causes, Effects of excessive exertion
6.9
7.9
20
20
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
5.3
7.8
24
31
B01AB05
ATC
enoxaparin; parenteral
1.2
7.8
1015
5825
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.9
7.7
46
108
D10AX03
ATC
azelaic acid; topical
0.5
7.7
83
1021
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
2.6
7.7
55
143
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.1
7.7
43
96
WGA11
SPAT
NA
0.2
7.6
7
249
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
2.1
7.6
82
266
OAB44
SPAT
NA
0.6
7.6
132
1439
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
0.7
7.5
218
2143
SPAT1373
SPAT
Combined screening in early pregnancy
2.4
7.5
63
179
WX610
NOMESCO Finland
Patient controlled analgesia
5.3
7.5
23
30
W92
ICPC
Compl labour/ delivery livebirth
2.5
7.5
58
160
MBW96
NOMESCO Finland
Other operation after delivery or abortion
25.1
7.4
11
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
6.2
7.4
20
22
X23
ICPC
Fear sexually transm dis female
1.4
7.3
397
2011
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
1.6
7.3
190
826
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
7.3
1626
9862
Z30.8
ICD-10 Finland
Other contraceptive management
1.6
7.2
173
737
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
6.0
7.2
20
23
WZA10
SPAT
NA
0.4
7.2
29
493
N03AX12
ATC
gabapentin; oral
1.3
7.2
475
2487
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
+∞
7.2
8
*
W99
ICPC
Disorder of pregn/delivery other
10.6
7.1
14
9
OAA70
SPAT
NA
2.7
7.1
46
115
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.1
7.1
78
255
SPAT1301
SPAT
No procedures
1.2
7.0
1563
9463
L05
ICPC
Flank/axilla symptom/complaint
1.6
7.0
199
885
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.4
7.0
335
1661
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
7.0
683
3778
OAB38
SPAT
NA
0.5
7.0
53
719
D10BA01
ATC
isotretinoin; oral
0.6
6.9
96
1104
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
6.9
390
1991
RS120
NOMESCO Finland
NA
4.8
6.9
23
33
SPAT1263
SPAT
Sampling
1.2
6.9
1977
12246
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
1.6
6.9
165
701
SPAT1153
SPAT
Removal of sutures
1.2
6.9
1068
6236
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.5
6.9
244
1142
N30.0
ICD-10 Finland
Acute cystitis
1.2
6.9
865
4937
RS331
NOMESCO Finland
NA
8.6
6.8
15
12
W12
ICPC
Contraception intrauterine
1.4
6.8
403
2074
MAA00
NOMESCO Finland
Amniocentesis
4.6
6.8
23
34
D06
ICPC
Abdominal pain localized other
1.4
6.7
374
1903
C10AA07
ATC
rosuvastatin; oral
1.3
6.7
617
3385
S18
ICPC
Laceration/cut
1.2
6.7
1463
8833
K04.1
ICD-10 Finland
Necrosis of pulp
1.5
6.7
198
889
N05AH04
ATC
quetiapine; oral
1.3
6.6
560
3041
F91.9
ICD-10 Finland
Conduct disorder, unspecified
4.5
6.6
23
35
D11
ICPC
Diarrhoea
1.3
6.5
441
2315
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
6.5
587
3214
P15
ICPC
Chronic alcohol abuse
3.4
6.5
31
63
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
6.5
3076
19886
B18.2
ICD-10 Finland
Chronic viral hepatitis C
5.9
6.5
18
21
SPAT1240
SPAT
Therapeutic discussion
1.3
6.5
493
2638
W14
ICPC
Contraception female other
1.4
6.5
393
2031
X14
ICPC
Vaginal discharge
1.7
6.5
133
543
N02AX02
ATC
tramadol; systemic, rectal
1.2
6.4
1179
6994
OIKK
NOMESCO Finland
NA
0.7
6.4
149
1529
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
3.4
6.4
30
60
ZYC01
SPAT
NA
0.7
6.4
194
1891
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
3.0
6.4
36
82
OAA41
SPAT
NA
2.5
6.4
50
138
OIKH
NOMESCO Finland
NA
0.6
6.3
85
983
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
6.3
265
1281
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
3.2
6.3
32
68
SPAT1363
SPAT
Health check-up performed during first study year in students of upper secondary schools, vocational schools etc.
0.8
6.3
727
5907
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
5.6
6.3
18
22
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.5
6.3
199
909
O48
ICD-10 Finland
Prolonged pregnancy
2.2
6.2
60
186
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
0.0
6.2
*
108
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
2.4
6.1
49
138
O20
ICD-10 Finland
Haemorrhage in early pregnancy
8.9
6.1
13
10
P16
ICPC
Acute alcohol abuse
3.2
6.0
31
67
L03
ICPC
Low back symptom/complaint
1.2
6.0
1000
5870
Z39.1
ICD-10 Finland
Care and examination of lactating mother
2.6
6.0
43
115
Mortality – FinRegistry
↥Association
Association between endpoint O15_PREG_ABORT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_PREG_ABORT | 0.826 [0.74, 0.92] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.291 |
During the follow-up period (1.1.1998 — 31.12.2019), 1999 out of 259017 females with O15_PREG_ABORT died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_PREG_ABORT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | No data |
| 5 | 0.499% | No data |
| 10 | 1.237% | No data |
| 15 | 2.398% | No data |
| 20 | 4.276% | No data |
Relationships between endpoints
↥Index endpoint: O15_PREG_ABORT – Pregnancy with abortive outcome
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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