Other abortion

O15_ABORT_OTHER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O05
  • Hospital discharge: ICD-9 636
  • Hospital discharge: ICD-8 642
  • Cause of death: ICD-10 O05
  • Cause of death: ICD-9 636
  • Cause of death: ICD-8 642

2 out of 7 registries used, show all original rules.

321

4. Check minimum number of events

None

321

5. Include endpoints

None

321

6. Filter based on genotype QC (FinnGen only)

321

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O00-O08
Name in latin
Alius abortus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2310 2310 -
Only index persons 2242 2242 -
Unadjusted period prevalence (%)
Whole population 0.07 0.07 -
Only index persons 0.08 0.08 -
Median age at first event (years)
Whole population - 29.33 -
Only index persons - 29.17 -

-FinnGen-

Key figures

All Female Male
Number of individuals 321 321 -
Unadjusted period prevalence (%) 0.11 0.11 -
Median age at first event (years) 30.73 30.73 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
282
Matched controls
2820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1419.5
104.2
95
*
O02.1
ICD-10 Finland
Missed abortion
691.5
58.9
56
*
O05.9
ICD-10 Finland
Other abortion, complete or unspecified, without complication
+∞
53.9
50
*
LCH11
NOMESCO Finland
Pharmacologic abortion
206.5
50.7
51
*
O05.1
ICD-10 Finland
Other abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
49.4
46
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
41.7
39
*
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
393.6
35.8
35
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
66.2
35.3
40
7
O05.6
ICD-10 Finland
Other abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
35.1
33
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
42.0
34.9
43
12
O05.4
ICD-10 Finland
Other abortion, incomplete, without complication
+∞
33.0
31
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
74.4
29.6
33
5
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
115.6
29.3
31
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
+∞
28.6
27
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
310.7
28.3
28
*
O05.0
ICD-10 Finland
Other abortion, incomplete, complicated by genital tract and pelvic infection
+∞
27.5
26
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.7
23.3
74
166
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.6
22.9
163
780
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
22.2
21
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
5.2
21.6
75
185
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
52.2
20.5
24
5
6360A
ICD-9 Finland
Illegally induced abortion, Complicated by genital tract and pelvic infection
+∞
20.0
19
*
8511
FHL
Cervical dilation and drainage with suction
+∞
20.0
19
*
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
+∞
17.9
17
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
16.8
16
*
64210
ICD-8 Finland
Abortion induced for other reasons, With haemorrhage
+∞
16.8
16
*
W79
ICPC
Unwanted pregnancy
+∞
16.8
16
*
8502
FHL
Evacuation and abrasion
63.8
16.0
18
*
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
14.7
14
*
64299
ICD-8 Finland
Abortion induced for other reasons, Without mention of sepsis, haemorrhage or laceration
+∞
14.7
14
*
O20.0
ICD-10 Finland
Threatened abortion
11.4
14.6
27
26
W83
ICPC
Abortion induced
+∞
13.6
13
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
13.6
13
*
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
12.6
12
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
9.1
12.6
26
31
ZXE00
NOMESCO Finland
One hour or less
2.5
12.0
139
792
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
11.5
11
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
+∞
10.5
10
*
O05.3
ICD-10 Finland
Other abortion, incomplete, with other and unspecified complications
+∞
10.5
10
*
O05.5
ICD-10 Finland
Other abortion, complete or unspecified, complicated by genital tract and pelvic infection
+∞
10.5
10
*
O04.4
ICD-10 Finland
Medical abortion, incomplete, without complication
+∞
10.5
10
*
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
+∞
10.5
10
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
3.2
10.1
56
202
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.7
9.5
42
127
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
9.2
9.5
19
22
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
+∞
9.4
9
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.9
9.3
63
258
P01AB01
ATC
metronidazole; oral, rectal
2.2
8.9
138
863
XLA10
NOMESCO Finland
NA
4.5
8.8
31
76
N96
ICD-10 Finland
Habitual aborter
92.7
8.5
9
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.4
8.4
87
448
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
8.4
8
*
6368X
ICD-9 Finland
Illegally induced abortion, With unspecified complication
+∞
8.4
8
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
8.4
8
*
ZXD05
NOMESCO Finland
Urgent procedure
2.2
7.9
103
592
Z37.0
ICD-10 Finland
Single live birth
2.6
7.6
61
272
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
82.2
7.5
8
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.7
7.5
53
223
8501
FHL
Emptying the uterus with suction
+∞
7.3
7
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
6.3
7.2
18
30
R51.80
ICD-10 Finland
Headache
2.4
7.1
63
299
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
6.7
111
691
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
6.3
6
*
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
+∞
6.3
6
*

Mortality – FinRegistry

Association

Association between endpoint O15_ABORT_OTHER and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_ABORT_OTHER.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_ABORT_OTHER – Other abortion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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