Medical abortion

O15_ABORT_MEDICAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O04
  • Hospital discharge: ICD-9 635
  • Hospital discharge: ICD-8 64[01]
  • Cause of death: ICD-10 O04
  • Cause of death: ICD-9 635
  • Cause of death: ICD-8 64[01]

2 out of 7 registries used, show all original rules.

50439

4. Check minimum number of events

None

50439

5. Include endpoints

None

50439

6. Filter based on genotype QC (FinnGen only)

50439

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O00-O08
Name in latin
Abortus medicinalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 413370 413370 -
Only index persons 395127 395127 -
Unadjusted period prevalence (%)
Whole population 11.84 11.84 -
Only index persons 14.53 14.53 -
Median age at first event (years)
Whole population - 24.96 -
Only index persons - 24.82 -

-FinnGen-

Key figures

All Female Male
Number of individuals 50439 50439 -
Unadjusted period prevalence (%) 17.19 17.19 -
Median age at first event (years) 25.05 25.05 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6163
Matched controls
44517
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
7.8
323.0
1081
1181
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
323.0
1815
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
88.5
323.0
444
39
LCH11
NOMESCO Finland
Pharmacologic abortion
622.3
323.0
1505
23
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
2199.0
323.0
1975
10
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
323.0
1015
*
W79
ICPC
Unwanted pregnancy
72.3
323.0
678
76
64090
ICD-8 Finland
Artificial termination of pregnancy performed for medical reasons, Woman's illness or physical defect (medicines. Cause)
+∞
323.0
509
*
64099
ICD-8 Finland
Abortion induced for medical indications, Without mention of sepsis or toxaemia
+∞
323.0
526
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
4.8
245.2
951
1619
W83
ICPC
Abortion induced
159.2
231.7
274
13
SPAT1371
SPAT
Assessment of need for induced abortion
105.1
194.3
238
17
64190
ICD-8 Finland
Artificial termination of pregnancy performed on the basis of another legal reason, Humanitarian reason
+∞
192.6
209
*
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
148.1
161
*
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
1155.8
138.6
153
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
231.1
133.9
155
5
O04
ICD-10 Finland
Medical abortion
185.0
128.0
150
6
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
122.2
133
*
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
920.7
112.8
125
*
64094
ICD-8 Finland
NA
+∞
103.8
113
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
97.3
1856
8108
O02.1
ICD-10 Finland
Missed abortion
248.1
88.5
102
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
19.5
83.5
140
53
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.4
80.1
773
2477
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
4.2
78.3
335
604
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
6.2
75.2
225
271
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
+∞
74.3
81
*
W01
ICPC
Question of pregnancy
6.6
73.2
209
236
Z3232
NOMESCO Finland
Midwife
3.2
73.1
430
1011
8511
FHL
Cervical dilation and drainage with suction
67.5
64.7
83
9
SPAT1372
SPAT
Follow-up examination after induced abortion
265.3
63.6
73
*
W78
ICPC
Pregnancy
1.9
63.5
1056
4277
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.4
63.3
620
1988
O04.4
ICD-10 Finland
Medical abortion, incomplete, without complication
+∞
62.4
68
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.5
62.2
561
1720
6350D
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORT PROV LEGAL SINE COMPL,ÄIDIN IKÄ <17 V TAI >40]
+∞
61.4
67
*
R2110
NOMESCO Finland
Giving the first information
2.7
58.7
457
1289
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.2
55.0
669
2371
SPAT1196
SPAT
Monitoring of normal pregnancy
3.9
54.2
244
460
P01AB01
ATC
metronidazole; oral, rectal
1.6
54.1
2095
10897
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
54.1
59
*
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
13.5
54.0
103
56
Z37.0
ICD-10 Finland
Single live birth
2.9
53.8
373
978
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.0
53.1
750
2833
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
52.3
57
*
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.6
52.1
434
1269
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
50.6
765
2965
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.3
49.1
115
2634
MAX99
NOMESCO Finland
Assistance to normal delivery
2.5
47.7
416
1249
SPAT1197
SPAT
Extensive health check-up of expecting family
1.9
47.1
817
3326
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
385.0
46.9
53
*
SPAT1379
SPAT
Health check-up of pregnant person
1.8
46.1
867
3630
Z2221
NOMESCO Finland
Medical doctor
1.6
45.6
1578
7905
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.2
45.3
496
1669
O04.5
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by genital tract and pelvic infection
+∞
44.0
48
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.8
43.5
861
3663
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
42.6
1454
7233
O04.3
ICD-10 Finland
Medical abortion, incomplete, with other and unspecified complications
+∞
42.2
46
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
178.3
41.9
49
*
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.2
39.3
425
1419
KAY40
NOMESCO Finland
NA
0.3
38.3
73
1851
KAY20
NOMESCO Finland
NA
0.2
37.9
55
1611
SPAT1380
SPAT
Postpartum check-up
1.8
37.2
676
2785
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.9
36.0
243
626
64093
ICD-8 Finland
Artificial termination of pregnancy performed for a medical reason, Other medical reason
+∞
34.8
38
*
WZB00
SPAT
NA
0.5
34.0
266
3800
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
33.9
37
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.2
33.5
374
1269
D10
ICPC
Vomiting
1.9
33.4
534
2095
64598
ICD-8 Finland
Other abortion
+∞
33.0
36
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
52.2
32.6
43
6
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
61.1
32.6
42
5
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
138.0
32.0
38
*
64595
ICD-8 Finland
Other abortion, Haemorrhagia post abortum NUD
+∞
31.1
34
*
N02BE01
ATC
paracetamol; systemic, rectal
1.5
30.8
5129
34169
O04.8
ICD-10 Finland
Medical abortion, complete or unspecified, with other and unspecified complications
+∞
30.2
33
*
Z51.2
ICD-10 Finland
Other chemotherapy
89.6
30.1
37
*
Y4301
ICD-8 Finland
Preventive sterilization, Legal sterilization, medico-social reasons (weakness)
3.7
29.3
140
280
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.4
29.3
279
874
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.0
28.6
422
1604
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
14.0
28.1
52
27
J01DB01
ATC
cefalexin; oral
1.4
26.0
4602
30280
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.0
25.8
158
383
64591
ICD-8 Finland
Other abortion, Endometritis post abortum
+∞
25.6
28
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
25.4
1919
11016
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
24.8
2136
12517
ZXE00
NOMESCO Finland
One hour or less
1.4
24.7
2104
12305
O99.80
ICD-10 Finland
The fear of childbirth
2.4
24.3
217
660
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.7
23.9
111
218
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
23.8
26
*
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
2.7
23.4
176
487
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.6
23.4
608
2776
SPAT1189
SPAT
Other ultrasound examination during pregnancy
2.4
23.0
214
665
63150
ICD-8 Finland
Ectopic pregnancy, Tubaria rupta, sepsi non indicata
+∞
22.9
25
*
M54.5
ICD-10 Finland
Low back pain
1.4
22.5
1801
10385
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
21.9
175
500
W29
ICPC
Pregnancy symptom/complaint other
2.6
21.8
166
463
LCH25
SPAT
NA
181.4
21.5
25
*
T74.1
ICD-10 Finland
Physical abuse
3.4
21.2
110
237
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.9
21.1
352
1402
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
20.9
2092
12456
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
62.9
20.4
26
*
64300
ICD-8 Finland
Spontaneous abortion, With sepsis
+∞
20.1
22
*
W90
ICPC
Uncompl labour/delivery livebirth
1.9
20.1
298
1134
ZXD05
NOMESCO Finland
Urgent procedure
1.4
20.1
1493
8479
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.7
19.4
137
366
D01
ICPC
Abdominal pain/cramps general
1.5
19.1
843
4349
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
19.0
4825
32455
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
18.9
604
2901
04300
ICD-8 Finland
NA
11.9
18.4
36
22
W14
ICPC
Contraception female other
1.5
18.1
611
2972
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
6.8
18.1
48
51
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.8
18.1
126
335
N76.0
ICD-10 Finland
Acute vaginitis
1.7
17.8
442
1989
N02AX02
ATC
tramadol; systemic, rectal
1.3
17.8
1872
11158
Z30.8
ICD-10 Finland
Other contraceptive management
1.9
17.6
273
1059
M03BX02
ATC
tizanidine; oral
1.3
17.4
2492
15465
LCH96
NOMESCO Finland
Other termination of pregnancy
144.9
17.0
20
*
Z2446
NOMESCO Finland
Social worker
1.7
17.0
378
1648
SPAT1187
SPAT
General ultrasound examination in early pregnancy
5.2
17.0
56
79
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
17.0
402
1784
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
76.1
16.9
21
*
SPAT1185
SPAT
Medical abortion
76.1
16.9
21
*
J01CA08
ATC
pivmecillinam; oral
1.3
16.9
3295
21207
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
3.3
16.9
88
192
SPAT1272
SPAT
Drug screening
8.3
16.7
39
34
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.9
16.5
246
943
O20.0
ICD-10 Finland
Threatened abortion
6.1
16.4
47
56
P19
ICPC
Drug abuse
4.1
16.4
67
119
W02
ICPC
Fear of pregnancy
3.0
16.3
97
233
X92
ICPC
Chlamydia infection genital female
2.0
16.2
222
823
R74
ICPC
Upper respiratory infection acute
1.3
16.1
1748
10433
R51.80
ICD-10 Finland
Headache
1.4
16.1
888
4776
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.1
15.7
180
620
-2
ICD-10 Finland
NA
0.4
15.7
76
1284
O80.8
ICD-10 Finland
Other single spontaneous delivery
1.9
15.7
228
865
SPAT1366
SPAT
Health check-up performed based on health survey in students of universities, universities of applied sciences etc.
0.5
15.5
169
2200
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
2.6
15.4
117
328
W84
ICPC
Pregnancy high risk
2.1
15.4
188
664
Y4302
ICD-8 Finland
Preventive sterilization, Legal sterilization, social reasons
3.4
15.4
79
171
OAB42
SPAT
NA
0.6
15.4
204
2522
M01AB05
ATC
diclofenac; systemic, rectal
1.2
15.4
2818
17920
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.9
15.2
95
235
KAY60
NOMESCO Finland
NA
0.3
15.1
36
819
SPAT1283
SPAT
Restricted health certificate
1.3
15.1
1153
6533
A03
ICPC
Fever
1.4
15.1
989
5469
ZYC02
SPAT
NA
0.4
15.1
80
1309
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
5.8
14.9
44
55
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
14.9
197
721
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.0
14.8
200
737
W12
ICPC
Contraception intrauterine
1.5
14.6
620
3169
B01AB05
ATC
enoxaparin; parenteral
1.3
14.4
1591
9491
J01AA02
ATC
doxycycline; systemic
1.2
14.3
3686
24264
TMA00
NOMESCO Finland
Episiotomy
2.7
14.3
99
263
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
14.3
2537
16025
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.9
14.2
92
235
N06AX11
ATC
mirtazapine; oral
1.3
13.9
1675
10091
Z72.2
ICD-10 Finland
Drug use
6.2
13.8
39
46
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
13.7
15
*
64191
ICD-8 Finland
Artificial termination of pregnancy performed on the basis of another legal reason, Heredity danger (racial reason)
+∞
13.7
15
*
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.4
13.7
670
3518
Z32
ICD-10 Finland
Pregnancy examination and test
4.0
13.6
56
101
D09
ICPC
Nausea
1.5
13.6
430
2059
N05BA04
ATC
oxazepam; oral
1.3
13.5
1336
7840
Y4308
ICD-8 Finland
Preventive sterilization, Legal preventive sterilization performed for other reasons
2.5
13.5
111
327
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
2.5
13.4
110
324
Z3231
NOMESCO Finland
Registered nurse
1.3
13.3
1404
8310
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.3
13.3
68
148
SGA01
NOMESCO Finland
Tooth opening as first aid
1.5
13.3
518
2599
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.1
13.2
159
560
30000
ICD-8 Finland
Neuroses, Anxiety neurosis
4.9
13.0
44
65
X23
ICPC
Fear sexually transm dis female
1.4
13.0
597
3093
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
6.2
12.9
36
42
K04.0
ICD-10 Finland
Pulpitis
1.6
12.9
335
1526
OAB39
SPAT
NA
0.5
12.7
131
1733
99450
ICD-8 Finland
Effects of other external causes, Effects of excessive exertion
6.1
12.7
36
43
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
12.7
854
4733
XMA22
NOMESCO Finland
General examination of pregnant woman
2.8
12.2
82
215
N07BA03
ATC
varenicline; oral
2.5
12.1
94
269
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
2.9
12.1
74
183
R03AC02
ATC
salbutamol; inhalant
1.2
12.0
2744
17692
63151
ICD-8 Finland
Ectopic pregnancy, Tubaria NUD sepsi non indicata
+∞
11.9
13
*
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.9
11.8
76
194
1412
FHL
Laparoscopy and sterilization
2.3
11.8
114
367
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.8
11.7
77
200
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
54.3
11.7
15
*
O05
ICD-10 Finland
Other abortion
101.3
11.7
14
*
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.3
11.6
113
364
M54
ICD-10 Finland
Dorsalgia
1.4
11.5
593
3140
P15
ICPC
Chronic alcohol abuse
3.5
11.4
54
111
R05
ICPC
Cough
1.3
11.4
1350
8087
WX110
NOMESCO Finland
Local anesthesy
1.2
11.2
3778
25227
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.8
11.2
207
858
WZC00
SPAT
NA
0.6
11.0
163
1960
Z35.6
ICD-10 Finland
Supervision of very young primigravida
5.6
11.0
33
43
64593
ICD-8 Finland
Other abortion, Abortus inhibitus, cum abortu
+∞
11.0
12
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
2.3
10.9
100
313
N01
ICPC
Headache
1.3
10.9
939
5391
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
10.8
1172
6939
K04.08
ICD-10 Finland
Other specified pulpit
1.7
10.8
220
939
D73
ICPC
Gastroenteritis presumed infection
1.9
10.7
168
659
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
2.2
10.6
108
355
D11
ICPC
Diarrhoea
1.3
10.6
698
3850
N07BB01
ATC
disulfiram; oral
3.2
10.5
55
123
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.3
10.5
102
329
Z72.0
ICD-10 Finland
Tobacco use
2.5
10.5
85
249
WX320
NOMESCO Finland
Spinalanesthesy
1.3
10.4
1069
6282
WX402
NOMESCO Finland
General anaesthesia
1.4
10.4
630
3429
N30.0
ICD-10 Finland
Acute cystitis
1.3
10.4
1180
7023
K04.1
ICD-10 Finland
Necrosis of pulp
1.5
10.3
339
1639
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
10.3
1049
6154
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
4.3
10.3
39
66
MA3AE
NOMESCO Finland
Combined first trimester screening
1.5
10.3
324
1552
W05
ICPC
Pregnancy vomiting/nausea
2.5
10.3
79
227
F92.0
ICD-10 Finland
Depressive conduct disorder
4.0
10.2
42
77
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.5
10.2
352
1719
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
10.1
555
2971
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
10.1
914
5282
O05.9
ICD-10 Finland
Other abortion, complete or unspecified, without complication
+∞
10.1
11
*
O21
ICD-10 Finland
Excessive vomiting in pregnancy
2.6
10.0
73
202
R3110
NOMESCO Finland
Psychosocial training
3.2
10.0
53
120
IHZ05
SPAT
NA
0.5
10.0
85
1185
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
10.0
1851
11621
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.6
10.0
250
1130
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.4
10.0
83
249
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.6
9.9
74
209
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
86.8
9.9
12
*
D06
ICPC
Abdominal pain localized other
1.4
9.9
543
2906
SAB02
NOMESCO Finland
Oral and dental health check by dental hygienist or dental assistant
0.7
9.9
371
3704
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
9.9
699
3899
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
0.5
9.9
63
961
OAB36
SPAT
NA
0.4
9.8
36
676
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
9.8
2195
14026
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.4
9.8
583
3161
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
0.6
9.8
166
1933
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.8
2323
14929
RS120
NOMESCO Finland
NA
4.9
9.7
32
47
P16
ICPC
Acute alcohol abuse
3.3
9.7
50
111
F91.9
ICD-10 Finland
Conduct disorder, unspecified
5.1
9.7
31
44
SPAT1281
SPAT
Other administrative function
1.4
9.7
488
2573
MBW96
NOMESCO Finland
Other operation after delivery or abortion
16.5
9.6
16
7
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.1
9.5
103
351
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.4
9.5
82
250
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
2.8
9.5
63
166
QXA70
SPAT
NA
0.3
9.4
21
490
N05AH04
ATC
quetiapine; oral
1.3
9.4
781
4455
OIKK
NOMESCO Finland
NA
0.5
9.4
101
1315
B86
ICD-10 Finland
Scabies
2.1
9.4
104
357
RS121
NOMESCO Finland
NA
3.4
9.4
46
99
N71.9
ICD-10 Finland
Inflammatory disease of uterus, unspecified
3.5
9.3
43
88
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
9.3
446
2332
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.0
9.3
127
475
SAB03
NOMESCO Finland
Oral health check
0.5
9.2
90
1205
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
9.2
467
2467
O03.5
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by genital tract and pelvic infection
+∞
9.2
10
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
9.1
252
1171
SPAT1364
SPAT
Health check-up performed during second study year in students of upper secondary schools, vocational schools etc.
0.7
9.1
258
2703
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
1.8
9.1
145
575
N05CF02
ATC
zolpidem; oral
1.3
9.0
686
3867
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
8.9
645
3607
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
1.9
8.9
132
511
W27
ICPC
Fear of complications of pregnancy
3.1
8.8
49
114
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
8.7
538
2936
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.7
1693
10647
M01AX17
ATC
nimesulide; oral
1.2
8.7
1066
6388
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.3
8.6
799
4626
R11
ICD-10 Finland
Nausea and vomiting
1.3
8.6
545
2986
W85
ICPC
Gestational diabetes
1.7
8.6
169
715
A02BC02
ATC
pantoprazole; systemic
1.2
8.6
3231
21529
SGC10
NOMESCO Finland
Covering pulpa of tooth
1.4
8.6
368
1886
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.5
8.6
319
1589
WZA10
SPAT
NA
0.4
8.5
32
589
SPAT1195
SPAT
Antenatal classes
1.9
8.5
130
508
L03
ICPC
Low back symptom/complaint
1.2
8.5
1466
9113
T51.0
ICD-10 Finland
Toxic effect: Ethanol
3.3
8.4
42
92
62200
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Endometritis acuta
3.1
8.4
47
110
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
8.4
1611
10114
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
3.3
8.3
41
89
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
0.4
8.3
38
650
B18.2
ICD-10 Finland
Chronic viral hepatitis C
4.2
8.3
31
53
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
39.8
8.3
11
*
SPAT1263
SPAT
Sampling
1.2
8.3
2765
18221
X14
ICPC
Vaginal discharge
1.7
8.3
178
775
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.5
8.3
317
1589
WX610
NOMESCO Finland
Patient controlled analgesia
4.0
8.3
33
60
MAA00
NOMESCO Finland
Amniocentesis
3.7
8.2
36
71
64499
ICD-8 Finland
Abortion not specified as induced or spontaneous, Without mention of sepsis or toxaemia
+∞
8.2
9
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.2
774
4489
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
8.2
139
561
Z71.8
ICD-10 Finland
Other specified counselling
1.2
8.2
1368
8466
R51
ICD-10 Finland
Headache
1.5
8.2
290
1427
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
8.2
921
5460
G01AA10
ATC
clindamycin; vaginal
1.3
8.2
561
3113
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
2.3
8.1
71
221
P02
ICPC
Acute stress reaction
1.6
8.1
208
950
D10AX03
ATC
azelaic acid; topical
0.6
8.0
147
1681
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.4
8.0
394
2070
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
8.0
945
5637
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
8.0
659
3757
8502
FHL
Evacuation and abrasion
6.3
7.9
21
24
OAB44
SPAT
NA
0.6
7.9
160
1789
F43.01
ICD-10 Finland
Acute stress reaction moderate
2.6
7.9
55
151
AA1AD
NOMESCO Finland
CT of head and brain
1.2
7.9
1254
7722
W82
ICPC
Abortion spontaneous
5.3
7.9
24
33
N05CF01
ATC
zopiclone; oral
1.2
7.8
1618
10221
N17
ICPC
Vertigo/dizziness
1.3
7.8
815
4793
J01EA01
ATC
trimethoprim; systemic
1.2
7.7
1770
11275
S29
ICPC
Skin symptom/complaint other
1.2
7.7
995
5992
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
1.8
7.7
133
542
U01
ICPC
Dysuria/painful urination
1.3
7.7
650
3716
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
7.7
2286
14892
N61
ICD-10 Finland
Inflammatory disorders of breast
1.9
7.7
114
442
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
26.5
7.7
11
*
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.6
7.6
207
961
Z36.8
ICD-10 Finland
Other antenatal screening
2.4
7.6
64
193
F41.09
ICD-10 Finland
UNS Panic Syndrome
1.7
7.6
163
710
S18
ICPC
Laceration/cut
1.2
7.6
2183
14175
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
7.6
356
1856
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
7.6
377
1987
J01DA01
ATC
[U] cefalexin; systemic
1.2
7.5
3077
20544
N06AB03
ATC
fluoxetine; oral
1.3
7.5
569
3206
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
7.4
915
5479
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
7.4
314
1605
IGY02
NOMESCO Finland
Psychiatric monitoring contact
1.9
7.4
104
396
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
4.6
7.4
25
39
N06AB04
ATC
citalopram; systemic
1.2
7.4
881
5257
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
7.3
1320
8222
O07.4
ICD-10 Finland
Failed medical abortion, without complication
+∞
7.3
8
*
64192
ICD-8 Finland
Artificial termination of pregnancy performed on the basis of another legal reason, Increased risk of damage to the fetus
+∞
7.3
8
*
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
+∞
7.3
8
*
OIKH
NOMESCO Finland
NA
0.5
7.3
53
773
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
1.6
7.3
167
743
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
2.0
7.3
89
322
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
6.9
7.2
18
19
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.1
7.2
80
278
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.6
7.2
53
150
SPAT1342
SPAT
Referral to specialised care
2.3
7.2
67
214
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.3
7.2
645
3718
N06AB10
ATC
escitalopram; oral
1.2
7.2
935
5634
U02
ICPC
Urinary frequency/urgency
1.2
7.2
1046
6375
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.2
2560
16889
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.2
7.2
838
4987
S06.0
ICD-10 Finland
Concussion
1.3
7.2
587
3342
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.9
7.1
102
391
F12.1
ICD-10 Finland
Mental and behavioural disorders due to use of cannabinoids, harmful use
5.1
7.1
22
31
SPAT1254
SPAT
Administration of medicine
1.2
7.1
1178
7275
G44.2
ICD-10 Finland
Tension-type headache
1.3
7.1
693
4035
8221
FHL
Sterilization of the laparotomy pathway
3.4
7.1
34
73
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
2.2
7.1
72
241
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
7.2
7.1
17
17
X84
ICPC
Vaginitis/vulvitis NOS
2.2
7.1
67
218
F40.01
ICD-10 Finland
Agoraphobia with concomitant panic disorder
3.0
7.0
40
97
WGA11
SPAT
NA
0.3
7.0
12
316
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.4
7.0
400
2158
Y04.0
ICD-10 Finland
Assault by bodily force by spouse or partner
4.2
7.0
26
45
N03AX16
ATC
pregabalin; oral
1.2
7.0
1067
6538
N05BA12
ATC
alprazolam; oral
1.4
6.9
383
2056
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.7
6.9
47
127
D06BB04
ATC
podophyllotoxin; topical
1.6
6.9
172
784
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
6.9
994
6055
N05BA01
ATC
diazepam; systemic, rectal
1.3
6.8
604
3474
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.7
6.8
125
523
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.7
6.8
44
117
SPAT1192
SPAT
Gynaecological examination
1.2
6.8
764
4527
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
2.0
6.8
81
292
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.2
6.7
888
5356
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
1.4
6.7
365
1954
N06AB05
ATC
paroxetine; oral
1.6
6.7
167
758
C10AA05
ATC
atorvastatin; oral
1.2
6.7
1746
11221
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.3
6.7
61
193
R42
ICD-10 Finland
Dizziness and giddiness
1.2
6.7
1332
8364
X45
ICD-10 Finland
Accidental poisoning by and exposure to alcohol
3.1
6.7
36
85
WX002
NOMESCO Finland
Sedation and analgesia
1.2
6.7
1009
6171
SBB10
NOMESCO Finland
Teeth copy
0.7
6.6
199
2062
R02
ICPC
Shortness of breath/dyspnoea
1.3
6.6
731
4321
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
6.6
1050
6451
G03HB01
ATC
cyproterone and estrogen; systemic
0.7
6.6
196
2032
P17
ICPC
Tobacco abuse
2.3
6.5
58
183
J02AC01
ATC
fluconazole; systemic
1.2
6.5
1887
12224
D05AX52
ATC
calcipotriol, combinations; topical
1.7
6.5
141
619
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
6.5
619
3595
F43.0
ICD-10 Finland
Acute stress reaction
1.6
6.5
155
698
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
8.4
6.5
14
12
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.4
6.4
385
2093
G43.9
ICD-10 Finland
Migraine, unspecified
1.4
6.4
265
1352
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
1.9
6.4
90
343
X59
ICD-10 Finland
Exposure to unspecified factor
1.2
6.4
809
4854
64510
ICD-8 Finland
NA
+∞
6.4
7
*
O07.6
ICD-10 Finland
Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage
+∞
6.4
7
*
R95
ICPC
Chron obstructive pulmonary disease
2.0
6.4
80
293
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.4
6.4
281
1448
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
2.0
6.4
74
264
OAB38
SPAT
NA
0.5
6.4
60
808
A56.2
ICD-10 Finland
Chlamydial infection of genitourinary tract, unspecified
3.6
6.3
28
57
R21
ICPC
Throat symptom/complaint
1.2
6.3
1410
8935
SPAT1154
SPAT
Insertion or removal of subcutaneous medicine capsule
1.7
6.3
129
555
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.4
6.3
53
161
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.3
6.3
508
2885
85000
ICD-8 Finland
Concussion, Current or unspecified
2.3
6.3
56
176
ZXE10
NOMESCO Finland
More than one and less than three hours
1.2
6.3
1639
10528
Z02.4
ICD-10 Finland
Examination for driving licence
1.2
6.3
978
6001
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.2
6.2
61
203
SAA01
NOMESCO Finland
Simple examination of mouth
1.1
6.2
3673
25032
13199
ICD-8 Finland
Trichomoniasis urogenitalis, Unspecified
7.8
6.2
14
13
ZYC05
SPAT
NA
0.5
6.2
34
540
00000
ICD-8 Finland
NA
2.4
6.2
50
151
T90
ICPC
Diabetes non-insulin dependent
1.2
6.2
903
5504
Z72.1
ICD-10 Finland
Alcohol use
2.9
6.2
36
90
SGC40
NOMESCO Finland
Restauration of tooth for rooth therapy
2.2
6.1
60
198
RS211
NOMESCO Finland
NA
3.3
6.1
29
63
M01AH05
ATC
etoricoxib; oral
1.2
6.1
2256
14872
30050
ICD-8 Finland
Neuroses, Neurasthenia
4.1
6.1
23
41
XMA20
NOMESCO Finland
Early examination of pregnancy
4.1
6.1
23
41
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
6.1
661
3901
Y6099
ICD-8 Finland
Prenatal care and observation
1.7
6.1
123
529
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.1
6.0
2496
16580

Mortality – FinRegistry

Association

Association between endpoint O15_ABORT_MEDICAL and mortality.

Females

Parameter HR [95% CI] p-value
O15_ABORT_MEDICAL 1.193 [1.06, 1.34] 0.003
Birth year 0.992 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 1349 out of 148808 females with O15_ABORT_MEDICAL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_ABORT_MEDICAL.

N-year risk Females Males
1 0.126% No data
5 0.649% No data
10 1.661% No data
15 3.135% No data
20 5.46% No data

Relationships between endpoints

Index endpoint: O15_ABORT_MEDICAL – Medical abortion

GWS hits: 6

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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