No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
542 |
4. Check minimum number of eventsNone |
542 |
5. Include endpointsNone |
542 |
6. Filter based on genotype QC (FinnGen only) |
542 |
Control definitions (FinnGen only)
- Control exclude
- O15_PREG_ABORT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O00-O08
- Name in latin
- Mola hydatidosa
Similar endpoints
↥List of similar endpoints to
Hydatidiform mole
based on the number of shared cases.
Similar with more cases:
- Pregnancy with abortive outcome
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4171 | 4171 | - |
| Only index persons | 4060 | 4060 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.12 | - |
| Only index persons | 0.15 | 0.15 | - |
| Median age at first event (years) | |||
| Whole population | - | 30.10 | - |
| Only index persons | - | 29.99 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 542 | 542 | - |
| Unadjusted period prevalence (%) | 0.18 | 0.18 | - |
| Median age at first event (years) | 30.19 | 30.19 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 494
- Matched controls
- 4939
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O01.0
ICD-10 Finland
Classical hydatidiform mole
+∞
163.9
148
*
O01.9
ICD-10 Finland
Hydatidiform mole, unspecified
+∞
154.5
140
*
O02.1
ICD-10 Finland
Missed abortion
1526.3
125.8
117
*
O01.1
ICD-10 Finland
Incomplete and partial hydatidiform mole
+∞
108.4
100
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
93.8
87
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
219.4
89.6
90
5
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
471.4
82.5
80
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
35.9
69.0
89
30
63420
ICD-8 Finland
Other complications of pregnancy, Missed abotion and missed delivery
+∞
67.2
63
*
6300A
ICD-9 Finland
Hydatidiform mole[MOLA HYDATIDOSA]
+∞
64.0
60
*
8502
FHL
Evacuation and abrasion
106.7
60.5
65
7
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
627.4
57.9
56
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
55.3
52
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
+∞
54.2
51
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
84.3
48.0
53
7
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
+∞
47.7
45
*
64592
ICD-8 Finland
Other abortion, Mola hydatidosa cum abortu
+∞
42.3
40
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.9
41.8
130
280
Z32.1
ICD-10 Finland
Pregnancy confirmed
4.8
34.1
128
334
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
11.7
26.2
49
46
LCH11
NOMESCO Finland
Pharmacologic abortion
47.1
25.8
31
7
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
28.0
25.2
34
13
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
24.2
23
*
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
+∞
23.1
22
*
8501
FHL
Emptying the uterus with suction
240.7
22.8
23
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
22.0
21
*
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
22.0
21
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.6
21.4
107
351
D39.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Placenta
+∞
19.9
19
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
23.7
19.3
27
12
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
+∞
18.9
18
*
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
17.8
17
*
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
+∞
15.7
15
*
8511
FHL
Cervical dilation and drainage with suction
+∞
15.7
15
*
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
15.7
15
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
6.6
15.5
40
65
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.2
15.3
234
1434
ZXD05
NOMESCO Finland
Urgent procedure
2.3
15.1
185
1022
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
14.7
14
*
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
+∞
14.7
14
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
154.4
14.5
15
*
N96
ICD-10 Finland
Habitual aborter
43.9
14.2
17
*
O20.0
ICD-10 Finland
Threatened abortion
7.1
13.7
33
49
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
6.1
12.6
34
59
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
11.5
11
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
11.5
11
*
V03AF03
ATC
calcium folinate; systemic
+∞
11.5
11
*
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
+∞
10.5
10
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
10.2
130
708
SPAT1379
SPAT
Health check-up of pregnant person
2.4
10.1
93
435
ZXE00
NOMESCO Finland
One hour or less
1.9
9.8
210
1396
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
4.4
9.8
35
85
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
9.4
9
*
C58
ICD-10 Finland
Malignant neoplasm of placenta
+∞
9.4
9
*
W78
ICPC
Pregnancy
2.1
9.2
118
644
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
4.9
9.2
29
62
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
9.2
188
1227
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.7
9.0
64
261
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
+∞
8.4
8
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.0
8.3
122
699
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.3
8.1
76
357
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.7
7.9
209
1462
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.3
7.9
75
355
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.1
7.6
90
472
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
7.6
117
683
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.0
7.5
97
528
6370A
ICD-9 Finland
Unspecified abortion, Complicated by genital tract and pelvic infection
+∞
7.3
7
*
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
7.3
7
*
W82
ICPC
Abortion spontaneous
17.0
6.8
10
6
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
6.7
86
466
WX400
NOMESCO Finland
Inhalation anesthesy
3.2
6.6
33
109
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.7
6.5
43
169
SPAT1196
SPAT
Monitoring of normal pregnancy
2.3
6.5
62
296
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
5.8
6.5
17
30
MAA00
NOMESCO Finland
Amniocentesis
4.0
6.5
24
62
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
6.4
159
1075
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.1
6.3
33
113
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
+∞
6.3
6
*
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
LBC21
NOMESCO Finland
Laparoscopic salpingotomy and removal of products of conception
+∞
6.3
6
*
6331A
ICD-9 Finland
Ectopic pregnancy, Tubal pregnancy
+∞
6.3
6
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.8
6.1
121
763
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.1
135
880
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.9
6.1
92
531
Mortality – FinRegistry
↥Association
Association between endpoint O15_PREG_HYDAT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_PREG_HYDAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_PREG_HYDAT – Hydatidiform mole
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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