Hydatidiform mole

O15_PREG_HYDAT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O01
  • Hospital discharge: ICD-9 630
  • Hospital discharge: ICD-8 6342|64592
  • Cause of death: ICD-10 O01
  • Cause of death: ICD-9 630
  • Cause of death: ICD-8 6342|64592

2 out of 7 registries used, show all original rules.

548

4. Check minimum number of events

None

548

5. Include endpoints

None

548

6. Filter based on genotype QC (FinnGen only)

530

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O00-O08
Name in latin
Mola hydatidosa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4171 4171 -
Only index persons 4060 4060 -
Unadjusted period prevalence (%)
Whole population 0.12 0.12 -
Only index persons 0.15 0.15 -
Median age at first event (years)
Whole population - 30.10 -
Only index persons - 29.99 -

-FinnGen-

Key figures

All Female Male
Number of individuals 530 530 -
Unadjusted period prevalence (%) 0.19 0.19 -
Median age at first event (years) 30.20 30.20 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
548
Matched controls
5480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O01.0
ICD-10 Finland
Classical hydatidiform mole
+∞
181.7
164
*
O01.9
ICD-10 Finland
Hydatidiform mole, unspecified
+∞
174.6
158
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
41.9
157.1
97
28
O02.1
ICD-10 Finland
Missed abortion
+∞
140.9
129
*
O01.1
ICD-10 Finland
Incomplete and partial hydatidiform mole
+∞
130.6
120
*
8502
FHL
Evacuation and abrasion
76.2
123.8
67
10
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
60.3
113.6
64
12
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
104.6
97
*
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
282.9
94.8
94
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
145.1
92.3
96
8
63420
ICD-8 Finland
Other complications of pregnancy, Missed abotion and missed delivery
+∞
72.5
68
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
772.2
70.7
68
*
6300A
ICD-9 Finland
Hydatidiform mole[MOLA HYDATIDOSA]
+∞
66.0
62
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
64.9
61
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
13.3
61.8
61
51
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.3
60.4
149
359
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
331.8
59.5
59
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
5.1
59.3
155
392
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
286.6
52.1
52
*
64592
ICD-8 Finland
Other abortion, Mola hydatidosa cum abortu
+∞
49.7
47
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
71.7
35.5
40
6
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
31.6
30
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
7.0
29.8
47
72
LCH11
NOMESCO Finland
Pharmacologic abortion
39.5
29.7
37
10
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.3
26.7
118
417
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
+∞
26.3
25
*
8501
FHL
Emptying the uterus with suction
+∞
25.2
24
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
41.0
25.1
31
8
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
24.1
23
*
O20.0
ICD-10 Finland
Threatened abortion
7.3
23.2
35
51
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
23.0
277
1619
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
6.2
22.6
40
69
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
+∞
22.0
21
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
22.0
21
*
D39.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Placenta
+∞
21.0
20
*
ZXD05
NOMESCO Finland
Urgent procedure
2.4
20.1
205
1098
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
18.9
18
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
+∞
18.9
18
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
5.0
16.4
36
76
N96
ICD-10 Finland
Habitual aborter
61.9
15.8
18
*
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
15.7
15
*
8511
FHL
Cervical dilation and drainage with suction
+∞
15.7
15
*
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
+∞
15.7
15
*
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
15.7
15
*
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
5.0
15.1
33
69
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
14.6
14
*
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
82.4
14.6
16
*
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
13.6
13
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.8
13.3
70
269
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
13.2
155
857
SPAT1379
SPAT
Health check-up of pregnant person
2.3
12.8
112
548
ZXE00
NOMESCO Finland
One hour or less
1.9
12.2
233
1522
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.9
11.6
35
95
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
5.9
11.6
21
37
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.1
11.5
142
794
WX400
NOMESCO Finland
Inhalation anesthesy
3.7
11.2
36
102
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.3
10.9
88
415
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
10.4
10
*
C58
ICD-10 Finland
Malignant neoplasm of placenta
+∞
10.4
10
*
W82
ICPC
Abortion spontaneous
23.9
10.3
14
6
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.3
10.1
89
434
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.1
10.1
108
570
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.8
9.8
237
1637
W78
ICPC
Pregnancy
2.0
9.8
139
812
V03AF03
ATC
calcium folinate; systemic
56.0
9.7
11
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
4.9
9.6
21
44
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.1
9.3
102
542
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
9.0
128
746
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.7
8.7
208
1420
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
50.8
8.7
10
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.5
8.7
59
257
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
+∞
8.4
8
*
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
+∞
8.4
8
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
8.2
101
559
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.2
8.1
33
109
SPAT1196
SPAT
Monitoring of normal pregnancy
2.2
8.1
69
331
W79
ICPC
Unwanted pregnancy
13.3
7.9
13
10
LCA10
NOMESCO Finland
Curettage of body of uterus
3.5
7.9
27
80
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.0
7.7
34
118
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.9
7.5
108
629
O03
ICD-10 Finland
Spontaneous abortion
81.2
7.4
8
*
6370A
ICD-9 Finland
Unspecified abortion, Complicated by genital tract and pelvic infection
+∞
7.3
7
*
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
7.3
7
*
LBC21
NOMESCO Finland
Laparoscopic salpingotomy and removal of products of conception
+∞
7.3
7
*
MAA00
NOMESCO Finland
Amniocentesis
3.4
7.2
26
80
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.0
131
826
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.7
7.0
138
885
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
9.5
6.8
13
14
SPAT1380
SPAT
Postpartum check-up
1.9
6.7
84
466
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
6.5
116
720
6331A
ICD-9 Finland
Ectopic pregnancy, Tubal pregnancy
+∞
6.3
6
*
O03.8
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, with other and unspecified complications
+∞
6.3
6
*
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
O06.1
ICD-10 Finland
Unspecified abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
SPAT1197
SPAT
Extensive health check-up of expecting family
1.8
6.2
108
664

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
113
318
4.22
36.50
9.0
1.7
11343.91
6365.02
u/l
0.36
76
98
41
196
2.18
4.90
1.3
1.3
—
—
—
0
0
90
572
1.69
4.58
1.2
1.2
—
—
—
0
0
145
1044
1.53
4.38
1.9
1.6
—
—
—
0
0
117
825
1.53
3.85
1.9
1.5
—
—
—
0
0
59
350
1.77
3.84
1.3
1.4
—
—
—
0
0
255
2114
1.39
3.48
2.5
2.2
—
—
—
0
0
156
1229
1.38
2.79
2.5
2.8
48.71
22.28
ng/l
0.59
70
613
14
54
2.63
2.72
3.0
2.6
—
—
—
0
0
127
975
1.39
2.64
4.2
3.6
1.02
1.02
kg/l
0.13
20
129
6
11
5.50
2.55
1.5
1.3
—
—
—
0
0
13
51
2.59
2.46
1.5
1.3
35.88
26.49
nmol/l
0.63
13
40
84
607
1.45
2.44
1.8
1.9
—
—
—
0
0
36
214
1.73
2.39
1.4
1.4
—
—
—
0
0
334
2993
1.30
2.29
4.4
3.8
108.00
468.76
e6/l
—
5
37
12
49
2.48
2.11
1.7
1.3
—
—
—
0
0
15
70
2.18
2.00
1.5
1.4
—
—
—
0
0
9
33
2.76
1.94
1.6
1.2
—
—
—
0
0
235
2049
1.26
1.88
2.0
2.0
—
—
—
0
0
153
1271
1.28
1.82
2.6
2.3
54.68
57.54
u/l
0.40
143
1175
129
1052
1.30
1.77
1.4
1.6
0.77
0.78
mg/l
0.03
103
794
33
210
1.61
1.75
1.4
1.4
—
—
—
0
0
0
46
0.00
1.71
0.0
1.5
—
—
—
0
0
0
48
0.00
1.70
0.0
1.1
—
0.59
—
0
21
17
93
1.85
1.53
1.0
1.0
10.36
3.27
u/ml
—
7
45
5
15
3.35
1.52
1.0
1.5
—
—
—
0
0
0
44
0.00
1.52
0.0
1.5
—
2.90
—
0
28
0
44
0.00
1.52
0.0
1.5
—
6.11
—
0
30
0
44
0.00
1.52
0.0
1.5
—
0.35
—
0
30
15
267
0.55
1.50
3.5
5.6
1.13
1.20
mmol/l
0.12
15
260
32
211
1.55
1.49
1.4
1.4
—
—
—
0
0
149
1264
1.25
1.47
2.1
1.8
—
—
—
0
0
9
39
2.33
1.43
1.0
1.1
—
—
—
0
0
157
1350
1.23
1.36
2.2
1.9
—
—
—
0
0
33
225
1.50
1.34
1.0
1.1
—
—
—
0
0
148
1273
1.22
1.27
2.5
2.5
—
—
—
0
0
168
1468
1.21
1.23
4.1
7.6
1.10
1.09
inr
0.09
59
483
8
37
2.18
1.22
1.5
1.2
—
—
—
0
0
114
967
1.23
1.12
2.3
2.8
—
—
—
0
0
99
828
1.24
1.11
1.6
1.6
403.20
47011295.35
pmol/l
1.56
85
736
468
4510
1.26
1.11
4.9
5.1
1.99
1.78
mu/l
0.45
444
4280
145
1262
1.20
1.10
1.3
1.3
0.69
1.44
u/ml
1.71
44
349
173
1533
1.19
1.08
1.6
1.8
104.68
97.57
pmol/l
0.66
76
818
273
2516
1.17
1.05
3.2
2.8
64.46
68.84
ug/l
0.44
264
2390
335
3138
1.17
1.05
4.3
4.0
—
—
—
0
0
16
99
1.63
1.01
1.8
1.8
3.54
5.42
umol/l
—
10
74
14
84
1.68
0.98
2.6
2.0
—
—
—
0
0
142
1247
1.19
0.98
4.2
3.6
0.00
0.00
estimate
0.80
51
464
0
29
0.00
0.98
0.0
1.0
—
—
—
0
0
152
1343
1.18
0.98
3.3
2.8
—
—
—
0
0
0
31
0.00
0.96
0.0
1.0
—
—
—
0
0
72
592
1.25
0.95
1.1
1.1
—
—
—
0
0
38
287
1.35
0.94
3.0
2.4
—
—
—
0
0
469
4542
1.23
0.92
9.7
10.6
139.82
139.64
mmol/l
1.24
462
4428
5
101
0.49
0.90
1.0
2.0
43.18
38.17
g/l
—
5
95
6
111
0.54
0.84
1.0
1.8
0.59
3.71
ug/l
—
6
102
129
1143
1.17
0.80
2.8
2.8
20.00
148.63
e6/l
1.25
93
867
479
4662
1.22
0.80
10.9
10.4
16.79
18.67
mg/l
0.74
375
3574
79
671
1.21
0.79
1.8
2.4
85.98
92.67
ug/g
0.08
52
518
0
26
0.00
0.78
0.0
1.8
—
2.32
—
0
19
160
1444
1.15
0.78
2.0
1.5
—
—
—
0
0
247
2299
1.14
0.76
3.7
3.3
0.00
0.00
estimate
-0.00
55
480
506
4957
1.27
0.76
10.2
9.8
—
—
—
0
0
30
390
0.76
0.75
3.4
2.3
31.67
37.35
u/l
0.49
24
324
417
4021
1.16
0.73
4.3
4.3
37.25
38.04
mmol/mol
1.35
395
3804
249
2328
1.13
0.70
3.8
3.3
0.06
0.01
estimate
0.42
52
455
57
475
1.22
0.70
1.5
1.3
155.22
150.66
iu/ml
0.03
28
206
190
2054
0.89
0.68
2.1
2.2
78.95
76.15
nmol/l
0.70
177
1910
14
94
1.50
0.67
1.2
1.0
—
—
—
0
0
64
543
1.20
0.67
2.8
2.7
2.83
3.85
e6/l
0.89
35
277
110
978
1.16
0.66
2.1
2.1
289.55
4480.93
umol/l
3.47
98
871
8
128
0.62
0.64
1.4
1.2
—
139.09
—
0
11
412
3983
1.14
0.64
4.4
4.4
14.32
14.37
pmol/l
0.15
390
3748
8
131
0.60
0.64
1.4
1.3
—
1244.00
—
0
10
26
199
1.32
0.63
2.2
2.2
—
—
—
0
0
15
104
1.45
0.63
1.0
1.1
0.41
1.24
u/ml
—
7
52
20
267
0.74
0.62
1.3
1.8
1.17
1.41
g/l
0.54
20
253
119
1070
1.14
0.62
2.2
2.1
2.45
2.73
mg/l
1.03
106
935
19
255
0.74
0.61
3.1
3.3
5.88
5.85
kpa
0.06
19
250
309
3235
0.90
0.60
2.6
2.7
29.65
33.97
u/l
0.91
295
3083
0
21
0.00
0.60
0.0
1.3
—
80.44
—
0
21
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
58
494
1.19
0.59
1.3
1.3
27.33
30.37
iu/l
0.31
52
435
0
22
0.00
0.59
0.0
1.8
—
—
—
0
0
245
2308
1.11
0.58
4.9
4.4
0.00
0.00
estimate
0.50
52
464
70
608
1.17
0.58
2.0
2.2
14.01
14.34
umol/l
0.16
64
570
64
553
1.18
0.56
2.0
2.2
2.44
2.45
g/l
0.09
58
517
49
413
1.20
0.56
3.4
3.2
—
—
—
0
0
179
1661
1.12
0.56
3.3
5.0
1.23
1.22
mmol/l
0.77
165
1533
5
89
0.56
0.56
2.4
2.2
3.99
4.97
mmol/24h
—
5
78
466
4556
1.15
0.55
9.9
10.7
3.91
3.91
mmol/l
0.01
460
4426
115
1042
1.13
0.54
2.6
2.6
—
—
—
0
0
20
260
0.76
0.54
2.9
3.5
—
—
—
0
0
49
416
1.20
0.53
1.1
1.2
—
—
—
0
0
6
97
0.61
0.52
1.2
1.2
—
—
—
0
0
90
805
1.14
0.52
2.2
2.2
8.45
7.81
e6/l
0.10
81
730
191
2036
0.91
0.51
7.8
7.9
0.00
0.00
e9/l
0.20
163
1674
98
1084
0.88
0.51
3.5
3.0
7.18
7.25
mmol/l
0.06
87
960
80
712
1.14
0.49
1.5
1.4
—
—
—
0
0
7
45
1.56
0.49
1.4
1.1
—
—
—
0
0
39
327
1.21
0.49
2.1
2.6
11.18
5.40
e9/l
0.34
31
288
7
110
0.63
0.48
4.0
2.1
0.88
1.37
g/l
—
7
96
7
46
1.53
0.48
2.6
1.5
8.47
9.59
u/ml
—
7
46
89
987
0.88
0.48
3.9
3.7
6.07
8.26
mg/mmol
0.32
52
597
10
143
0.69
0.48
4.7
6.6
—
—
—
0
0
30
245
1.24
0.48
1.2
1.1
—
—
—
0
0
115
1051
1.12
0.47
1.3
1.4
1.96
2.10
g/l
0.80
78
696
155
1441
1.11
0.47
3.3
3.3
68.71
72.84
e6/l
0.03
105
941
69
611
1.15
0.46
2.5
3.0
50.76
284.09
ng/l
1.04
36
350
199
1876
1.10
0.45
4.0
5.7
1.23
1.22
mmol/l
1.28
170
1607
114
1045
1.11
0.45
2.7
2.6
0.13
0.35
e6/l
2.43
85
779
41
479
0.84
0.45
1.3
1.3
—
—
—
0
0
12
86
1.40
0.45
2.0
4.7
58.25
58.01
%
0.02
12
86
7
51
1.38
0.44
1.3
2.8
—
—
—
0
0
47
406
1.17
0.44
1.4
1.4
—
—
—
0
0
54
472
1.16
0.44
1.6
1.8
—
—
—
0
0
16
207
0.77
0.43
3.8
2.0
—
—
—
0
0
352
3408
1.09
0.43
3.5
3.9
9.38
10.19
mm/h
0.89
334
3194
13
173
0.75
0.42
2.5
3.5
130.62
128.21
g/l
0.24
13
168
17
131
1.31
0.42
1.8
1.7
—
—
—
0
0
119
1098
1.11
0.42
1.9
2.0
203.36
186.98
u/l
0.05
110
1041
431
4217
1.10
0.40
11.9
12.6
14.37
14.41
%
0.05
423
4138
5
34
1.47
0.40
1.2
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
7.8
—
119.08
—
0
13
0
18
0.00
0.40
0.0
2.7
—
0.15
—
0
18
17
215
0.78
0.39
3.8
7.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
68
755
0.89
0.39
1.3
1.4
912.73
616.37
titre
0.29
11
171
37
317
1.18
0.39
2.9
4.0
3.58
11.46
ug/l
1.39
26
242
43
492
0.86
0.38
1.5
1.6
—
—
—
0
0
31
262
1.19
0.38
1.4
1.3
181.58
224.82
miu/ml
—
10
144
105
969
1.10
0.38
1.2
1.3
46.69
24.16
iu/ml
0.33
31
336
5
77
0.65
0.36
5.6
3.8
0.77
0.87
nmol/l
—
5
65
6
43
1.40
0.35
2.0
1.3
—
—
—
0
0
20
243
0.82
0.34
4.3
1.7
—
—
—
0
0
30
350
0.85
0.34
1.2
1.2
—
—
—
0
0
28
328
0.85
0.33
3.4
4.2
0.14
0.12
%
—
7
73
14
110
1.28
0.32
1.0
1.1
—
—
—
0
0
14
110
1.28
0.32
1.0
1.1
—
—
—
0
0
53
477
1.12
0.31
1.2
1.3
—
—
—
0
0
43
482
0.88
0.30
1.2
1.3
—
—
—
0
0
10
130
0.76
0.29
2.8
2.3
0.57
0.66
%
—
10
130
87
936
0.92
0.29
3.4
3.2
853.41
454.79
mg/l
0.20
53
585
100
934
1.09
0.29
1.2
1.3
3.23
13.69
u/ml
3.26
35
421
8
106
0.75
0.29
1.5
10.1
0.83
0.95
%
—
8
97
148
1405
1.07
0.29
3.2
3.1
2.35
2.35
mmol/l
0.19
140
1277
194
1862
1.06
0.27
3.4
3.0
6.39
5.88
ph
1.53
18
181
9
120
0.75
0.27
5.3
2.4
9.54
10.61
mg/l
—
9
110
30
342
0.87
0.27
3.4
4.2
0.00
0.13
%
—
7
86
78
724
1.09
0.26
2.6
2.5
527.62
514.44
mosm/kgh2o
0.20
68
631
13
104
1.26
0.26
1.0
1.0
2.39
1.40
u/ml
—
5
38
11
86
1.28
0.26
2.1
4.3
4.16
4.24
e9/l
0.05
11
86
5
71
0.70
0.26
1.4
1.5
0.88
0.49
g/l
—
5
53
25
216
1.16
0.26
1.8
1.7
—
—
—
0
0
29
329
0.87
0.25
3.3
3.9
0.38
0.86
%
—
8
83
13
105
1.24
0.25
1.5
10.1
1.12
1.23
mmol/l
0.26
13
91
34
303
1.13
0.24
2.6
3.0
1.25
1.23
mmol/l
0.75
29
259
21
180
1.17
0.24
5.6
2.1
—
—
—
0
0
39
431
0.90
0.23
1.2
1.4
—
—
—
0
0
452
4574
0.93
0.22
3.7
3.6
1.58
1.58
mmol/l
0.02
433
4362
220
2131
1.05
0.22
5.2
5.1
8.45
9.50
umol/l
2.36
210
2014
5
40
1.25
0.22
1.2
1.6
7.06
10.72
umol/l
—
5
40
18
210
0.85
0.22
3.7
2.4
56.44
74.64
e9/l
—
8
151
32
357
0.89
0.22
3.3
4.1
0.33
1.02
%
—
9
101
20
172
1.17
0.22
1.5
8.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
62.33
—
0
6
0
10
0.00
0.21
0.0
2.4
—
5.90
—
0
10
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
530
5271
1.17
0.21
15.9
15.6
39.31
39.73
%
0.99
501
5037
54
499
1.09
0.21
2.0
2.3
23.36
23.59
%
0.05
45
429
0
12
0.00
0.21
0.0
1.1
—
0.02
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
216.67
—
0
6
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
20.95
—
0
14
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
9
115
0.78
0.20
3.0
2.5
—
—
—
0
0
530
5273
1.16
0.19
15.9
15.7
265.31
268.26
e9/l
0.57
524
5177
14
118
1.19
0.19
1.8
2.0
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
209
2150
0.95
0.19
5.2
5.9
—
—
—
0
0
12
100
1.20
0.18
1.1
1.1
—
—
—
0
0
7
62
1.13
0.17
1.1
1.3
—
—
—
0
0
7
62
1.13
0.17
1.1
1.1
—
—
—
0
0
16
183
0.87
0.16
2.1
2.7
—
—
—
0
0
57
536
1.07
0.16
1.4
1.9
—
—
—
0
0
197
1919
1.04
0.16
2.2
2.3
—
—
—
0
0
6
76
0.79
0.15
1.0
1.4
—
27.10
—
0
5
6
78
0.77
0.15
2.3
2.5
7.45
7.42
ph
—
6
67
455
4590
0.95
0.15
3.8
3.7
4.90
4.87
mmol/l
0.25
436
4394
81
849
0.95
0.15
1.5
1.5
22.58
22.03
nmol/l
0.12
73
752
62
655
0.94
0.15
1.6
1.5
—
—
—
0
0
13
112
1.16
0.14
1.6
5.3
—
—
—
0
0
216
2207
0.96
0.14
4.8
5.4
54.58
56.58
%
2.04
203
2088
13
149
0.87
0.13
1.2
1.2
—
—
—
0
0
530
5279
1.12
0.13
16.0
15.7
4.42
4.45
e12/l
1.40
523
5178
288
2926
0.97
0.13
2.7
2.9
—
—
—
0
0
530
5280
1.12
0.12
16.1
15.7
6.46
6.57
e9/l
0.68
525
5173
16
179
0.89
0.12
1.1
1.2
—
—
—
0
0
261
2653
0.97
0.12
8.0
8.4
3.74
3.91
e9/l
0.77
240
2357
34
317
1.08
0.12
1.4
1.2
—
—
—
0
0
13
114
1.14
0.12
1.0
1.0
6.38
2.97
u/ml
—
5
52
34
318
1.07
0.11
1.9
8.5
2.20
1.24
mmol/l
1.25
29
250
219
2229
0.97
0.11
4.9
5.6
30.82
29.44
%
1.38
208
2113
31
290
1.07
0.10
1.6
1.7
259.16
350.24
mu/l
1.20
25
264
30
320
0.93
0.10
1.9
8.4
5.26
5.13
kpa
0.25
30
304
30
320
0.93
0.10
1.9
8.4
14.52
13.53
kpa
0.33
30
304
5
44
1.14
0.10
4.4
2.1
62.60
63.53
%
—
5
44
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
61
586
1.05
0.09
1.9
1.6
1303.63
1198.78
nmol/l
0.48
53
458
45
472
0.95
0.09
2.6
2.0
5.51
5.17
umol/l
0.12
39
399
14
126
1.11
0.09
1.6
3.2
0.46
0.35
g/l
—
6
45
6
54
1.11
0.09
1.0
1.3
—
—
nmol/l
—
0
0
6
56
1.07
0.08
1.8
1.8
—
—
—
0
0
490
4922
0.96
0.08
8.7
8.8
23.04
23.59
u/l
0.40
481
4786
112
1147
0.97
0.08
1.8
1.6
1.34
1.28
mmol/l
0.22
97
1000
5
61
0.82
0.08
1.4
15.1
10.80
11.54
mmol/l
—
5
54
5
61
0.82
0.08
1.4
15.1
104.00
104.91
mmol/l
—
5
54
241
2380
1.02
0.08
4.7
5.8
0.19
0.18
e9/l
0.61
226
2136
11
98
1.12
0.07
1.5
1.5
—
—
—
0
0
328
3309
0.98
0.07
6.4
6.5
69.28
73.49
u/l
2.09
309
3127
8
78
1.03
0.07
1.1
1.6
—
—
—
0
0
225
2278
0.98
0.07
4.7
5.6
0.04
0.04
e9/l
0.51
203
2019
7
80
0.87
0.07
1.0
1.2
—
—
—
0
0
19
204
0.93
0.07
1.8
2.4
53.84
129.27
ng/l
1.79
19
176
9
88
1.02
0.07
1.8
1.5
—
—
—
0
0
212
2145
0.98
0.06
5.3
5.9
8.30
7.96
%
0.67
201
2027
12
109
1.10
0.06
6.3
2.1
—
—
—
0
0
437
4391
0.98
0.06
3.4
3.3
1.20
1.21
mmol/l
0.11
416
4158
37
355
1.05
0.06
3.2
2.7
—
—
—
0
0
225
2274
0.98
0.06
4.7
5.6
0.53
0.53
e9/l
0.17
203
2018
30
314
0.95
0.05
3.3
3.2
—
—
—
0
0
440
4380
1.02
0.05
3.6
3.7
5.58
5.65
mmol/l
0.69
418
4127
16
149
1.08
0.05
1.1
1.1
—
—
—
0
0
101
1028
0.98
0.05
3.8
3.3
—
—
—
0
0
462
4637
0.98
0.05
3.9
4.0
2.94
2.89
mmol/l
0.56
441
4414
19
179
1.06
0.05
1.4
1.2
—
—
—
0
0
11
101
1.09
0.04
2.3
2.8
25.32
24.85
mmol/l
0.77
11
93
25
261
0.96
0.04
3.9
1.7
—
—
—
0
0
13
121
1.08
0.03
2.0
2.7
—
—
—
0
0
25
260
0.96
0.03
3.6
1.7
—
—
—
0
0
70
688
1.02
0.03
2.5
2.2
2.42
2.43
mmol/l
0.16
65
619
12
128
0.94
0.02
4.1
3.3
24.50
24.06
mmol/l
0.22
12
128
25
259
0.96
0.02
3.6
1.7
—
—
—
0
0
117
1159
1.01
0.02
5.5
6.4
—
—
—
0
0
203
2042
0.99
0.02
4.8
5.7
0.72
0.69
%
0.48
189
1909
20
208
0.96
0.02
4.3
1.5
—
—
—
0
0
26
268
0.97
0.02
1.4
1.4
—
—
—
0
0
214
2129
1.01
0.02
4.8
5.6
3.01
2.73
%
1.21
203
2005
82
811
1.01
0.01
3.4
3.6
—
—
—
0
0
116
1151
1.01
0.01
3.2
3.4
7.40
7.40
ph
0.11
25
215
164
1631
1.01
0.01
4.1
4.1
37.21
36.68
g/l
0.66
152
1534
66
668
0.99
0.01
1.3
1.3
—
—
—
0
0
25
257
0.97
0.01
3.4
1.7
—
—
—
0
0
226
2268
0.99
0.01
3.0
4.0
6.05
6.37
mmol/l
2.49
205
2066
14
135
1.04
0.00
2.4
11.9
—
—
—
0
0
18
176
1.02
0.00
1.7
1.3
—
—
—
0
0
12
123
0.98
0.00
1.0
1.3
308.33
346.13
ug/g
—
6
65
24
239
1.00
0.00
5.2
7.2
6.86
8.11
mmol/l
0.58
24
231
236
2357
1.00
0.00
4.6
5.6
1.94
1.99
e9/l
0.36
221
2141
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
10.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
3.63
—
0
6
8
82
0.98
0.00
2.4
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
20.35
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
55
0.91
-0.00
4.4
3.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
13.68
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
58
0.86
-0.00
2.6
1.9
—
—
—
0
0
5
58
0.86
-0.00
7.2
3.6
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
35.80
—
0
5
0
5
0.00
-0.00
0.0
6.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
76
0.92
-0.00
6.0
3.4
34.93
32.08
mg/l
—
7
61
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
11.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
7
76
0.92
-0.00
6.0
3.4
19.77
22.72
mg/l
—
7
60
22
220
1.00
-0.00
1.7
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.34
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
96
0.94
-0.00
1.3
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_PREG_HYDAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PREG_HYDAT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_PREG_HYDAT – Hydatidiform mole

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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