Hydatidiform mole

O15_PREG_HYDAT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O01
  • Hospital discharge: ICD-9 630
  • Hospital discharge: ICD-8 6342|64592
  • Cause of death: ICD-10 O01
  • Cause of death: ICD-9 630
  • Cause of death: ICD-8 6342|64592

2 out of 7 registries used, show all original rules.

542

4. Check minimum number of events

None

542

5. Include endpoints

None

542

6. Filter based on genotype QC (FinnGen only)

542

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O00-O08
Name in latin
Mola hydatidosa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4171 4171 -
Only index persons 4060 4060 -
Unadjusted period prevalence (%)
Whole population 0.12 0.12 -
Only index persons 0.15 0.15 -
Median age at first event (years)
Whole population - 30.10 -
Only index persons - 29.99 -

-FinnGen-

Key figures

All Female Male
Number of individuals 542 542 -
Unadjusted period prevalence (%) 0.18 0.18 -
Median age at first event (years) 30.19 30.19 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
494
Matched controls
4939
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O01.0
ICD-10 Finland
Classical hydatidiform mole
+∞
163.9
148
*
O01.9
ICD-10 Finland
Hydatidiform mole, unspecified
+∞
154.5
140
*
O02.1
ICD-10 Finland
Missed abortion
1526.3
125.8
117
*
O01.1
ICD-10 Finland
Incomplete and partial hydatidiform mole
+∞
108.4
100
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
93.8
87
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
219.4
89.6
90
5
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
471.4
82.5
80
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
35.9
69.0
89
30
63420
ICD-8 Finland
Other complications of pregnancy, Missed abotion and missed delivery
+∞
67.2
63
*
6300A
ICD-9 Finland
Hydatidiform mole[MOLA HYDATIDOSA]
+∞
64.0
60
*
8502
FHL
Evacuation and abrasion
106.7
60.5
65
7
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
627.4
57.9
56
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
55.3
52
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
+∞
54.2
51
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
84.3
48.0
53
7
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
+∞
47.7
45
*
64592
ICD-8 Finland
Other abortion, Mola hydatidosa cum abortu
+∞
42.3
40
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.9
41.8
130
280
Z32.1
ICD-10 Finland
Pregnancy confirmed
4.8
34.1
128
334
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
11.7
26.2
49
46
LCH11
NOMESCO Finland
Pharmacologic abortion
47.1
25.8
31
7
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
28.0
25.2
34
13
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
24.2
23
*
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
+∞
23.1
22
*
8501
FHL
Emptying the uterus with suction
240.7
22.8
23
*
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
22.0
21
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
22.0
21
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.6
21.4
107
351
D39.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Placenta
+∞
19.9
19
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
23.7
19.3
27
12
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
+∞
18.9
18
*
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
17.8
17
*
8511
FHL
Cervical dilation and drainage with suction
+∞
15.7
15
*
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
15.7
15
*
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
+∞
15.7
15
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
6.6
15.5
40
65
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.2
15.3
234
1434
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
+∞
14.7
14
*
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
14.7
14
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
154.4
14.5
15
*
N96
ICD-10 Finland
Habitual aborter
43.9
14.2
17
*
O20.0
ICD-10 Finland
Threatened abortion
7.1
13.7
33
49
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
6.1
12.6
34
59
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
11.5
11
*
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
11.5
11
*
V03AF03
ATC
calcium folinate; systemic
+∞
11.5
11
*
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
+∞
10.5
10
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
10.2
130
708
SPAT1379
SPAT
Health check-up of pregnant person
2.4
10.1
93
435
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
4.4
9.8
35
85
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
9.4
9
*
C58
ICD-10 Finland
Malignant neoplasm of placenta
+∞
9.4
9
*
W78
ICPC
Pregnancy
2.1
9.2
118
644
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
4.9
9.2
29
62
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
9.2
188
1227
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.7
9.0
64
261
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
+∞
8.4
8
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.0
8.3
122
699
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.3
8.1
76
357
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.7
7.9
209
1462
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.3
7.9
75
355
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.1
7.6
90
472
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
7.6
117
683
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.0
7.5
97
528
6370A
ICD-9 Finland
Unspecified abortion, Complicated by genital tract and pelvic infection
+∞
7.3
7
*
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
7.3
7
*
W82
ICPC
Abortion spontaneous
17.0
6.8
10
6
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
6.7
86
466
WX400
NOMESCO Finland
Inhalation anesthesy
3.2
6.6
33
109
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.7
6.5
43
169
SPAT1196
SPAT
Monitoring of normal pregnancy
2.3
6.5
62
296
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
5.8
6.5
17
30
MAA00
NOMESCO Finland
Amniocentesis
4.0
6.5
24
62
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
6.4
159
1075
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.1
6.3
33
113
LBC21
NOMESCO Finland
Laparoscopic salpingotomy and removal of products of conception
+∞
6.3
6
*
6331A
ICD-9 Finland
Ectopic pregnancy, Tubal pregnancy
+∞
6.3
6
*
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
+∞
6.3
6
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.8
6.1
121
763
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.1
135
880
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.9
6.1
92
531

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
108
317
4.01
32.75
9.2
1.7
11808.9
5950.6
u/l
0.42
73
98
39
191
2.12
4.41
1.3
1.3
—
—
—
0
0
88
569
1.65
4.19
1.2
1.2
—
—
—
0
0
139
1018
1.49
3.83
1.8
1.6
—
—
—
0
0
111
799
1.49
3.30
1.9
1.6
—
—
—
0
0
251
2091
1.37
3.28
4.2
3.7
—
—
—
0
0
56
348
1.68
3.12
1.3
1.4
—
—
—
0
0
14
53
2.69
2.81
3.0
2.5
—
—
—
0
0
126
960
1.41
2.75
4.2
3.6
1.0
1.0
kg/l
0.13
20
129
13
48
2.75
2.73
1.5
1.3
35.9
27.1
nmol/l
0.56
13
37
6
11
5.50
2.55
1.5
1.3
—
—
—
0
0
83
601
1.45
2.39
1.9
1.9
—
—
—
0
0
12
48
2.53
2.20
1.7
1.3
—
—
—
0
0
151
1229
1.32
2.13
2.5
2.8
48.7
22.3
ng/l
0.59
70
612
328
2960
1.27
2.02
4.4
3.8
108.0
188.4
e6/l
—
5
35
9
32
2.84
2.01
1.6
1.2
—
—
—
0
0
0
46
0.00
1.71
0.0
1.5
—
—
—
0
0
33
212
1.59
1.69
1.5
1.4
—
—
—
0
0
231
2031
1.24
1.68
2.0
2.0
—
—
—
0
0
127
1043
1.28
1.65
1.4
1.6
0.8
0.8
mg/l
0.01
102
784
14
70
2.03
1.60
1.6
1.4
—
—
—
0
0
150
1263
1.26
1.59
2.7
2.3
54.0
55.9
u/l
0.27
140
1165
5
15
3.35
1.52
1.0
1.5
—
—
—
0
0
0
44
0.00
1.52
0.0
1.5
—
0.4
—
0
30
0
44
0.00
1.52
0.0
1.5
—
2.9
—
0
28
0
44
0.00
1.52
0.0
1.5
—
6.1
—
0
30
15
265
0.55
1.47
3.5
5.6
1.1
1.2
mmol/l
0.10
15
255
9
39
2.33
1.43
1.0
1.1
—
—
—
0
0
31
208
1.52
1.36
1.5
1.4
—
—
—
0
0
156
1342
1.23
1.35
2.2
1.9
—
—
—
0
0
33
226
1.49
1.32
1.0
1.1
—
—
—
0
0
16
92
1.76
1.26
1.0
1.0
11.3
3.6
u/ml
—
5
31
8
36
2.24
1.24
1.5
1.2
—
—
—
0
0
142
1227
1.21
1.17
2.1
1.8
—
—
—
0
0
143
1238
1.21
1.15
2.5
2.5
—
—
—
0
0
30
209
1.46
1.13
1.5
1.3
—
—
—
0
0
38
284
1.36
1.00
3.0
2.4
—
—
—
0
0
462
4463
1.24
0.99
4.9
5.1
2.0
1.8
mu/l
0.46
438
4234
0
29
0.00
0.98
0.0
2.3
—
896.3
—
0
12
72
591
1.25
0.97
1.1
1.1
—
—
—
0
0
268
2480
1.16
0.96
3.1
2.8
65.0
69.2
ug/l
0.41
259
2355
14
85
1.66
0.95
2.6
2.0
—
—
—
0
0
430
4454
0.83
0.94
11.3
11.2
38.8
39.5
%
1.07
342
3608
5
101
0.49
0.90
1.0
2.0
43.2
38.1
g/l
—
5
94
149
1324
1.17
0.89
3.2
2.9
—
—
—
0
0
329
3103
1.15
0.88
4.3
4.0
—
—
—
0
0
169
1521
1.16
0.86
1.6
1.8
104.2
97.7
pmol/l
0.57
74
809
5
96
0.52
0.78
1.0
1.2
—
—
—
0
0
140
1251
1.16
0.78
1.3
1.3
0.7
1.4
u/ml
1.71
44
350
0
26
0.00
0.78
0.0
1.8
—
2.1
—
0
19
0
27
0.00
0.77
0.0
1.0
—
—
—
0
0
15
99
1.53
0.76
1.7
1.9
3.5
5.5
umol/l
—
10
75
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
95
825
1.18
0.76
1.7
1.6
399.1
36835351.8
pmol/l
1.31
81
733
109
958
1.17
0.75
2.3
2.9
—
—
—
0
0
463
4502
1.20
0.75
9.7
10.6
139.8
139.6
mmol/l
1.36
456
4388
473
4610
1.20
0.73
10.8
10.4
16.7
18.7
mg/l
0.81
370
3527
137
1229
1.15
0.73
4.3
3.6
0.0
0.0
estimate
0.80
48
460
6
109
0.55
0.73
1.0
1.8
0.6
3.8
ug/l
—
6
100
6
109
0.55
0.73
4.5
2.1
0.9
1.4
g/l
—
6
95
110
971
1.17
0.72
2.1
2.1
289.8
4563.7
umol/l
3.46
97
854
126
1128
1.15
0.69
2.8
2.8
20.0
150.4
e6/l
1.25
91
855
80
692
1.18
0.68
1.6
1.4
—
—
—
0
0
14
94
1.50
0.67
1.2
1.0
—
—
—
0
0
26
198
1.33
0.65
2.2
2.2
—
—
—
0
0
8
128
0.62
0.64
1.4
1.3
—
1244.0
—
0
10
187
2016
0.89
0.63
7.5
8.0
0.0
0.0
e9/l
0.21
159
1662
413
3997
1.14
0.63
4.4
4.4
37.3
38.1
mmol/mol
1.26
391
3782
56
473
1.21
0.62
1.5
1.3
135.4
153.5
iu/ml
0.11
27
203
9
137
0.65
0.61
2.9
8.2
26.9
24.2
mmol/l
—
9
131
20
266
0.74
0.61
1.3
1.8
1.2
1.4
g/l
0.55
20
251
241
2265
1.12
0.61
3.7
3.3
0.0
0.0
estimate
0.00
48
445
77
671
1.17
0.61
1.6
2.4
84.1
92.0
ug/g
0.09
46
518
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.8
—
—
—
0
0
96
1075
0.87
0.59
3.5
3.0
7.1
7.3
mmol/l
0.22
85
941
19
253
0.74
0.59
3.1
3.3
5.9
5.9
kpa
0.00
19
248
500
4915
1.22
0.59
10.1
9.8
—
—
—
0
0
49
412
1.21
0.57
1.2
1.2
—
—
—
0
0
40
481
0.82
0.56
1.3
1.3
—
—
—
0
0
154
1419
1.12
0.55
2.0
1.5
—
—
—
0
0
8
125
0.63
0.55
1.4
1.2
—
139.1
—
0
11
57
490
1.18
0.54
1.3
1.3
27.8
30.3
iu/l
0.25
51
431
243
2297
1.10
0.54
3.8
3.3
0.1
0.0
estimate
0.42
49
450
6
39
1.54
0.53
1.2
1.3
—
—
—
0
0
6
39
1.54
0.53
1.2
1.3
—
—
—
0
0
6
39
1.54
0.53
1.2
1.3
—
—
—
0
0
6
39
1.54
0.53
1.2
1.3
—
—
—
0
0
88
982
0.88
0.52
4.0
3.9
6.2
8.3
mg/mmol
0.30
51
594
66
752
0.86
0.52
1.3
1.4
1008.9
617.1
titre
—
9
171
137
1259
1.12
0.51
2.9
5.5
1.1
1.1
inr
0.22
48
429
20
258
0.77
0.51
3.0
3.5
—
—
—
0
0
177
1650
1.11
0.51
3.3
5.0
1.2
1.2
mmol/l
0.69
162
1510
10
144
0.69
0.49
4.7
6.5
—
—
—
0
0
406
3947
1.11
0.49
4.5
4.4
14.3
14.4
pmol/l
0.26
384
3715
7
45
1.56
0.49
1.4
1.1
—
—
—
0
0
116
1061
1.12
0.47
2.2
2.1
2.5
2.7
mg/l
1.04
103
927
68
602
1.15
0.46
2.0
2.2
14.2
14.3
umol/l
0.05
61
559
46
396
1.18
0.44
1.5
1.4
—
—
—
0
0
17
130
1.32
0.44
1.8
1.7
—
—
—
0
0
27
328
0.81
0.44
3.0
4.2
0.2
0.1
%
—
6
65
7
51
1.38
0.44
1.3
2.8
—
—
—
0
0
38
322
1.19
0.44
6.6
12.4
1.1
1.2
inr
—
8
52
62
548
1.15
0.43
2.0
2.2
2.4
2.5
g/l
0.12
56
514
239
2278
1.09
0.42
4.9
4.4
0.0
0.0
estimate
0.50
49
460
16
206
0.77
0.42
3.8
2.0
—
—
—
0
0
197
1863
1.09
0.42
4.1
5.7
1.2
1.2
mmol/l
1.35
166
1577
68
607
1.14
0.42
2.5
3.0
50.8
284.0
ng/l
1.04
36
350
112
1031
1.11
0.41
2.6
2.6
—
—
—
0
0
460
4517
1.12
0.41
9.9
10.7
3.9
3.9
mmol/l
0.08
454
4387
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.7
—
0.1
—
0
18
0
19
0.00
0.39
0.0
7.6
—
158.1
—
0
14
37
317
1.18
0.39
2.9
4.0
3.6
11.5
ug/l
1.39
26
242
19
236
0.80
0.38
4.4
1.7
—
—
—
0
0
13
170
0.76
0.38
2.6
3.5
130.4
128.5
g/l
0.18
13
165
29
243
1.20
0.38
1.1
1.1
—
—
—
0
0
29
343
0.84
0.38
3.0
4.2
0.0
0.1
%
—
7
80
53
469
1.14
0.38
1.7
1.8
—
—
—
0
0
87
795
1.11
0.37
2.2
2.2
8.6
7.8
e6/l
0.13
78
707
8
115
0.69
0.37
2.8
2.6
—
—
—
0
0
112
1038
1.10
0.37
1.3
1.4
1.9
2.1
g/l
0.91
76
682
17
212
0.80
0.36
3.8
7.3
—
—
—
0
0
5
77
0.65
0.36
5.6
3.8
0.8
0.9
nmol/l
—
5
65
43
489
0.87
0.35
1.6
1.6
—
—
—
0
0
28
330
0.84
0.35
2.9
3.9
0.8
0.8
%
—
5
62
5
80
0.62
0.35
2.6
2.4
7.4
7.4
ph
—
5
61
30
255
1.19
0.35
1.4
1.3
181.6
225.3
miu/ml
—
10
142
6
43
1.40
0.35
2.0
1.3
—
—
—
0
0
30
350
0.85
0.34
1.2
1.2
—
—
—
0
0
86
934
0.91
0.34
3.5
3.2
869.8
462.2
mg/l
0.20
52
575
111
1033
1.09
0.34
2.6
2.6
0.1
0.3
e6/l
2.34
83
765
148
1395
1.08
0.34
3.1
3.1
2.3
2.4
mmol/l
0.19
139
1260
208
2174
0.93
0.34
4.6
5.5
54.6
56.7
%
2.04
194
2054
31
358
0.86
0.32
3.0
4.1
0.3
1.0
%
—
7
88
14
110
1.28
0.32
1.0
1.1
—
—
—
0
0
14
110
1.28
0.32
1.0
1.1
—
—
—
0
0
151
1429
1.08
0.32
3.2
3.3
69.9
69.8
e6/l
0.00
103
933
17
208
0.81
0.31
3.8
2.5
56.4
74.3
e9/l
—
8
149
46
410
1.13
0.31
3.3
3.2
—
—
—
0
0
211
2197
0.94
0.30
4.8
5.7
30.9
29.5
%
1.36
198
2067
12
152
0.78
0.30
1.2
1.2
—
—
—
0
0
78
844
0.91
0.29
1.4
1.5
22.3
22.1
nmol/l
0.05
70
747
8
106
0.75
0.29
1.5
10.0
0.8
1.0
%
—
8
97
38
428
0.88
0.29
1.2
1.4
—
—
—
0
0
103
964
1.08
0.29
1.2
1.3
46.7
23.6
iu/ml
0.34
31
319
447
4534
0.92
0.29
3.7
3.7
1.6
1.6
mmol/l
0.00
427
4316
11
85
1.30
0.28
2.1
4.8
57.6
58.0
%
0.04
11
85
346
3380
1.07
0.28
3.5
3.9
9.4
10.2
mm/h
0.93
328
3170
112
1189
0.93
0.28
3.1
4.1
—
—
—
0
0
116
1094
1.08
0.27
1.9
2.0
206.3
187.2
u/l
0.06
107
1036
13
104
1.26
0.26
1.5
10.1
1.1
1.2
mmol/l
0.18
13
90
10
127
0.78
0.25
2.9
2.3
0.6
0.7
%
—
10
122
204
2114
0.94
0.25
5.1
5.9
8.4
8.0
%
0.76
193
1998
217
2244
0.95
0.25
4.5
5.6
0.5
0.5
e9/l
0.14
195
1993
255
2625
0.95
0.24
8.0
8.4
3.7
3.9
e9/l
0.74
234
2335
218
2254
0.95
0.24
4.5
5.7
0.0
0.0
e9/l
0.47
196
1999
13
158
0.82
0.24
1.0
1.3
—
2.6
—
0
19
20
171
1.18
0.23
1.5
8.1
—
—
—
0
0
5
40
1.25
0.22
1.2
1.6
7.1
10.7
umol/l
—
5
40
36
324
1.12
0.22
2.2
2.5
3.5
4.1
e9/l
1.99
28
274
50
460
1.10
0.21
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
69.2
—
0
5
0
10
0.00
0.21
0.0
2.4
—
5.9
—
0
10
57
528
1.09
0.21
1.4
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
4.4
2.1
62.6
64.3
%
—
5
43
450
4550
0.94
0.21
3.8
3.7
4.9
4.9
mmol/l
0.34
430
4348
0
13
0.00
0.21
0.0
1.8
—
216.7
—
0
6
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
20.9
—
0
14
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
20
174
1.16
0.20
6.5
2.2
—
—
—
0
0
75
706
1.07
0.19
2.5
2.5
538.3
527.5
mosm/kgh2o
0.15
66
609
323
3291
0.95
0.19
6.3
6.5
69.5
73.6
u/l
1.92
304
3100
24
213
1.13
0.19
1.8
1.7
—
—
—
0
0
412
4067
1.05
0.19
12.0
12.8
13.4
13.6
%
1.62
402
3979
6
53
1.13
0.18
1.0
1.4
—
—
—
0
0
12
100
1.20
0.18
1.1
1.1
—
—
—
0
0
44
475
0.92
0.18
1.2
1.4
—
—
—
0
0
60
639
0.93
0.17
1.6
1.5
—
—
—
0
0
7
62
1.13
0.17
1.1
1.1
—
—
—
0
0
5
69
0.72
0.17
1.4
1.5
0.9
0.5
g/l
—
5
51
10
120
0.83
0.16
4.9
2.4
9.6
10.6
mg/l
—
10
110
13
111
1.18
0.16
1.6
5.1
—
—
—
0
0
197
2021
0.96
0.15
4.6
5.8
0.7
0.7
%
0.46
183
1890
6
76
0.79
0.15
1.0
1.4
—
27.1
—
0
5
179
1743
1.04
0.15
3.4
3.0
—
—
—
0
0
133
1374
0.96
0.14
4.9
5.8
—
—
—
0
0
524
5218
1.13
0.14
15.8
15.8
265.4
268.2
e9/l
0.52
518
5122
33
305
1.09
0.14
2.7
3.0
1.3
1.2
mmol/l
0.84
28
261
12
103
1.17
0.14
1.7
1.9
—
—
—
0
0
12
103
1.17
0.14
1.0
1.0
2.4
1.5
u/ml
—
5
36
16
180
0.89
0.13
1.9
2.7
—
—
—
0
0
98
1017
0.96
0.13
3.8
3.3
—
—
—
0
0
228
2325
0.97
0.13
4.4
5.6
1.9
2.0
e9/l
0.35
210
2106
34
316
1.08
0.13
1.9
8.4
2.2
1.3
mmol/l
1.19
29
247
10
85
1.18
0.12
2.2
4.3
4.0
4.3
e9/l
—
10
85
286
2903
0.97
0.12
2.7
2.9
—
—
—
0
0
216
2118
1.03
0.12
5.3
5.1
8.4
9.5
umol/l
2.30
207
1996
16
178
0.90
0.11
1.1
1.2
—
—
—
0
0
44
465
0.94
0.11
2.7
2.0
5.5
5.2
umol/l
0.11
38
394
432
4353
0.96
0.11
3.4
3.3
1.2
1.2
mmol/l
0.06
411
4121
206
2099
0.97
0.11
4.7
5.6
3.0
2.7
%
1.24
195
1968
52
495
1.06
0.11
2.1
2.3
23.9
23.5
%
0.09
43
426
11
96
1.15
0.10
1.5
1.4
—
—
—
0
0
194
1904
1.03
0.10
2.2
2.3
—
—
—
0
0
14
125
1.12
0.10
1.6
3.1
0.5
0.4
g/l
—
6
44
96
931
1.04
0.10
1.2
1.3
3.3
13.5
u/ml
3.07
34
420
111
1140
0.97
0.09
1.9
1.6
1.3
1.3
mmol/l
0.25
96
993
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
19
174
1.10
0.09
1.4
1.2
—
—
—
0
0
5
48
1.04
0.09
2.4
2.0
—
—
—
0
0
457
4596
0.96
0.09
3.9
4.0
3.0
2.9
mmol/l
0.72
435
4362
524
5224
1.09
0.09
15.9
15.8
4.4
4.5
e12/l
1.37
517
5124
6
55
1.09
0.09
1.0
1.3
—
—
nmol/l
—
0
0
37
351
1.06
0.08
3.2
2.8
—
—
—
0
0
6
56
1.07
0.08
1.8
1.8
—
—
—
0
0
30
318
0.94
0.08
1.9
8.4
14.5
13.5
kpa
0.34
30
302
30
318
0.94
0.08
1.9
8.4
5.3
5.1
kpa
0.25
30
302
5
61
0.82
0.08
1.4
15.1
10.8
11.5
mmol/l
—
5
54
5
61
0.82
0.08
1.4
15.1
104.0
104.9
mmol/l
—
5
54
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
64
0.78
0.08
1.2
1.5
—
—
—
0
0
524
5226
1.08
0.07
16.0
15.8
6.5
6.6
e9/l
0.58
519
5120
7
80
0.87
0.07
1.0
1.2
—
—
—
0
0
9
88
1.02
0.07
1.8
1.5
—
—
—
0
0
8
92
0.87
0.07
1.4
1.2
—
—
—
0
0
19
203
0.93
0.06
1.8
2.4
53.8
129.0
ng/l
1.78
19
175
70
682
1.03
0.06
2.4
2.2
2.4
2.4
mmol/l
0.08
65
613
24
253
0.95
0.05
3.9
1.7
—
—
—
0
0
16
149
1.08
0.05
1.1
1.1
—
—
—
0
0
24
252
0.95
0.05
3.7
1.7
—
—
—
0
0
19
201
0.94
0.04
4.4
1.5
—
—
—
0
0
30
288
1.04
0.04
1.5
1.7
266.5
348.8
mu/l
1.00
24
262
24
251
0.95
0.04
3.7
1.7
—
—
—
0
0
33
319
1.04
0.03
1.3
1.2
—
—
—
0
0
24
250
0.96
0.03
3.5
1.7
—
—
—
0
0
12
112
1.07
0.03
1.0
1.0
6.4
2.8
u/ml
—
5
50
224
2254
0.99
0.03
3.0
4.0
6.0
6.4
mmol/l
2.97
202
2049
26
269
0.96
0.02
1.4
1.4
—
—
—
0
0
435
4339
1.01
0.02
3.7
3.7
5.6
5.7
mmol/l
0.57
413
4089
65
660
0.98
0.02
1.3
1.3
—
—
—
0
0
116
1149
1.01
0.02
5.5
6.5
—
—
—
0
0
11
103
1.07
0.02
6.7
2.2
—
—
—
0
0
30
308
0.97
0.02
3.3
3.2
—
—
—
0
0
12
127
0.94
0.01
4.1
3.3
24.5
24.1
mmol/l
0.18
12
117
59
583
1.01
0.01
1.9
1.6
1295.3
1206.5
nmol/l
0.37
51
457
14
135
1.04
0.00
2.4
11.9
—
—
—
0
0
23
235
0.98
0.00
5.4
7.3
6.9
8.2
mmol/l
0.55
23
227
18
176
1.02
0.00
1.7
1.3
—
—
—
0
0
22
224
0.98
0.00
1.7
1.6
—
—
—
0
0
12
123
0.98
0.00
1.0
1.3
308.3
338.6
ug/g
—
6
65
10
102
0.98
0.00
2.4
2.8
25.3
24.8
mmol/l
—
10
94
114
1144
1.00
0.00
3.2
3.4
7.4
7.4
ph
0.12
24
217
12
121
0.99
0.00
2.1
2.7
—
—
—
0
0
162
1621
1.00
0.00
4.0
4.1
37.3
36.6
g/l
0.90
150
1521
235
2354
1.00
0.00
4.5
5.9
0.2
0.2
e9/l
0.67
220
2117
7
76
0.92
0.00
6.0
3.4
19.8
22.7
mg/l
—
7
60
7
76
0.92
0.00
6.0
3.4
34.9
32.1
mg/l
—
7
61
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
76
0.92
0.00
1.0
1.2
—
—
—
0
0
5
55
0.91
0.00
4.4
3.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
8
81
0.99
0.00
2.4
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.3
—
0
5
0
5
0.00
0.00
0.0
6.8
—
—
—
0
0
5
58
0.86
0.00
7.2
3.6
—
—
—
0
0
0
6
0.00
0.00
0.0
10.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
3.6
—
0
6
0
6
0.00
0.00
0.0
1.2
—
20.3
—
0
6
80
800
1.00
0.00
3.4
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
11.8
—
—
—
0
0
7
77
0.91
0.00
1.1
1.6
—
—
—
0
0
6
62
0.97
0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_PREG_HYDAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PREG_HYDAT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_PREG_HYDAT – Hydatidiform mole

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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