Failed attempted abortion

O15_ABORT_FAILED

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O07
  • Hospital discharge: ICD-9 638
  • Cause of death: ICD-10 O07
  • Cause of death: ICD-9 638

2 out of 7 registries used, show all original rules.

479

4. Check minimum number of events

None

479

5. Include endpoints

None

479

6. Filter based on genotype QC (FinnGen only)

479

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O00-O08
Name in latin
Tentamen abortus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4502 4502 -
Only index persons 4450 4450 -
Unadjusted period prevalence (%)
Whole population 0.13 0.13 -
Only index persons 0.16 0.16 -
Median age at first event (years)
Whole population - 28.56 -
Only index persons - 28.54 -

-FinnGen-

Key figures

All Female Male
Number of individuals 479 479 -
Unadjusted period prevalence (%) 0.16 0.16 -
Median age at first event (years) 30.48 30.48 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
437
Matched controls
4370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
8943.0
323.0
324
*
LCH11
NOMESCO Finland
Pharmacologic abortion
650.5
203.2
186
5
O07.6
ICD-10 Finland
Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage
+∞
165.4
148
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
1063.5
156.6
144
*
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
+∞
121.7
111
*
O07.4
ICD-10 Finland
Failed medical abortion, without complication
+∞
102.2
94
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
127.6
94.6
99
10
O07.1
ICD-10 Finland
Failed medical abortion, complicated by delayed or excessive haemorrhage
+∞
94.3
87
*
O02.1
ICD-10 Finland
Missed abortion
345.6
85.9
84
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
28.2
60.4
83
36
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.9
50.5
169
420
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
50.0
47
*
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
50.0
47
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
46.1
49.3
60
15
W79
ICPC
Unwanted pregnancy
134.4
45.8
48
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
46.1
43.7
53
13
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
43.5
41
*
O07.0
ICD-10 Finland
Failed medical abortion, complicated by genital tract and pelvic infection
+∞
41.3
39
*
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
40.2
38
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
52.5
39.7
47
10
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.9
39.4
277
1348
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
195.6
35.3
36
*
O07.9
ICD-10 Finland
Other and unspecified failed attempted abortion, without complication
+∞
31.6
30
*
8511
FHL
Cervical dilation and drainage with suction
+∞
30.6
29
*
P01AB01
ATC
metronidazole; oral, rectal
3.3
30.1
248
1256
R2110
NOMESCO Finland
Giving the first information
5.8
28.0
85
174
ZXD05
NOMESCO Finland
Urgent procedure
3.2
27.9
213
1002
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.8
26.3
134
460
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
276.1
26.0
26
*
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
10.7
24.5
48
50
O04.4
ICD-10 Finland
Medical abortion, incomplete, without complication
+∞
24.2
23
*
WX400
NOMESCO Finland
Inhalation anesthesy
7.1
23.0
58
92
ZXE00
NOMESCO Finland
One hour or less
2.8
22.6
230
1252
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
7.5
22.2
54
81
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.3
22.1
133
509
W83
ICPC
Abortion induced
231.1
21.8
22
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
21.6
131
502
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
21.0
20
*
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
+∞
21.0
20
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
76.8
19.9
22
*
O20.0
ICD-10 Finland
Threatened abortion
7.0
18.0
45
70
8502
FHL
Evacuation and abrasion
187.3
17.6
18
*
ZXD20
NOMESCO Finland
Day surgery
3.7
16.9
81
256
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
16.8
16
*
O07.3
ICD-10 Finland
Failed medical abortion, with other and unspecified complications
+∞
16.8
16
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
15.7
15
*
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
165.7
15.6
16
*
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
165.7
15.6
16
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
14.9
181
1012
LCA10
NOMESCO Finland
Curettage of body of uterus
7.2
14.5
35
52
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.7
13.7
109
485
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
13.6
167
929
6388X
ICD-9 Finland
Failed attempted abortion, With unspecified complication
+∞
13.6
13
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.2
12.6
169
972
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.6
12.6
108
497
SPAT1371
SPAT
Assessment of need for induced abortion
+∞
12.6
12
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.8
12.4
85
344
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
5.7
11.6
33
62
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.5
11.1
101
477
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
11.0
173
1048
SPAT1263
SPAT
Sampling
2.0
10.8
203
1321
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.6
10.8
50
153
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.1
10.5
142
807
O04.3
ICD-10 Finland
Medical abortion, incomplete, with other and unspecified complications
+∞
10.5
10
*
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
10.5
10
*
6381A
ICD-9 Finland
Failed attempted abortion, Complicated by delayed or excessive haemorrhage
+∞
10.5
10
*
J01DB01
ATC
cefalexin; oral
2.4
10.4
374
3127
M54.5
ICD-10 Finland
Low back pain
2.0
10.3
163
987
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
10.2
159
957
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
10.0
274
2029
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.9
9.9
259
1883
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.0
9.7
157
951
LCH96
NOMESCO Finland
Other termination of pregnancy
102.2
9.5
10
*
O07.2
ICD-10 Finland
Failed medical abortion, complicated by embolism
+∞
9.4
9
*
O04.8
ICD-10 Finland
Medical abortion, complete or unspecified, with other and unspecified complications
+∞
9.4
9
*
O04
ICD-10 Finland
Medical abortion
+∞
9.4
9
*
ULC02
NOMESCO Finland
Hysteroscopy
3.7
9.2
40
117
N06AB10
ATC
escitalopram; oral
2.1
9.1
130
748
R51.80
ICD-10 Finland
Headache
2.2
8.6
96
497
SPAT1283
SPAT
Restricted health certificate
1.9
8.6
146
898
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
8.5
112
619
Z2221
NOMESCO Finland
Medical doctor
1.9
8.4
148
918
Z3231
NOMESCO Finland
Registered nurse
2.1
8.4
109
600
O07.8
ICD-10 Finland
Other and unspecified failed attempted abortion, with other and unspecified complications
+∞
8.4
8
*
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
8.4
8
*
O07.5
ICD-10 Finland
Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection
+∞
8.4
8
*
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
8.4
8
*
R42
ICD-10 Finland
Dizziness and giddiness
2.3
8.1
76
360
R74
ICPC
Upper respiratory infection acute
1.8
8.1
192
1320
J01FF01
ATC
clindamycin; systemic
2.0
8.1
112
631
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.8
8.0
248
1848
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
8.0
184
1244
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.8
8.0
51
197
H01
ICPC
Ear pain/earache
2.4
7.9
68
309
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.8
7.9
282
2197
SPAT1260
SPAT
Consultation of another employee
2.3
7.9
79
387
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
7.8
191
1319
WX110
NOMESCO Finland
Local anesthesy
1.8
7.7
322
2632
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.8
7.6
226
1656
N05BA04
ATC
oxazepam; oral
2.0
7.6
117
685
Z87.4
ICD-10 Finland
Personal history of diseases of the genitourinary system
13.7
7.4
12
9
J01DA01
ATC
[U] cefalexin; systemic
1.8
7.4
276
2160
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
7.3
141
896
8519
FHL
Other measure in this category
+∞
7.3
7
*
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
7.3
7
*
8501
FHL
Emptying the uterus with suction
+∞
7.3
7
*
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
7.5
7.2
16
22
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
7.2
90
485
Z09.7
ICD-10 Finland
Follow-up examination after combined treatment for other conditions
30.6
7.2
9
*
N96
ICD-10 Finland
Habitual aborter
30.6
7.2
9
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.4
7.2
61
277
T74.1
ICD-10 Finland
Physical abuse
5.8
7.1
19
34
N05CF02
ATC
zolpidem; oral
2.1
7.1
88
472
N06AX11
ATC
mirtazapine; oral
1.8
7.1
135
853
L03
ICPC
Low back symptom/complaint
1.9
7.1
110
645
W01
ICPC
Question of pregnancy
6.5
7.0
17
27
WX290
NOMESCO Finland
Other blockade of nerve
1.7
7.0
246
1878
F43.0
ICD-10 Finland
Acute stress reaction
2.8
7.0
45
175
Z3232
NOMESCO Finland
Midwife
2.0
7.0
101
578
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.9
83
442
J01AA02
ATC
doxycycline; systemic
1.8
6.9
317
2614
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
3.8
6.8
27
74
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.2
6.7
65
315
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
6.6
62
294
WX702
NOMESCO Finland
Supraglottic ventilation device
3.7
6.6
27
76
D10
ICPC
Vomiting
2.5
6.6
50
214
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
6.6
79
419
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.3
6.6
64
308
SGC00
NOMESCO Finland
Local medication of root channels of tooth
2.2
6.5
66
324
A02BC02
ATC
pantoprazole; systemic
1.7
6.4
240
1840
SPAT1301
SPAT
No procedures
1.8
6.4
125
792
M77.1
ICD-10 Finland
Lateral epicondylitis
2.7
6.3
42
167
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
11.2
6.3
11
10
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.7
6.3
157
1072
G02CB01
ATC
bromocriptine; systemic
4.9
6.3
19
40
6380A
ICD-9 Finland
Failed attempted abortion, Complicated by genital tract and pelvic infection
+∞
6.3
6
*
O06.1
ICD-10 Finland
Unspecified abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
K02.1
ICD-10 Finland
Caries of dentine
1.7
6.2
279
2244
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
6.2
226
1718
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
4.2
6.2
22
55
J01CA08
ATC
pivmecillinam; oral
1.7
6.2
227
1728
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.1
6.1
75
400
SPAT1097
SPAT
Recording of ECG
2.8
6.1
37
140
F51.0
ICD-10 Finland
Nonorganic insomnia
2.0
6.1
79
434
Z30.2
ICD-10 Finland
Sterilization
2.2
6.0
63
315
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.0
6.0
32
111
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.2
6.0
60
292
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
6.0
45
190

Mortality – FinRegistry

Association

Association between endpoint O15_ABORT_FAILED and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_ABORT_FAILED.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_ABORT_FAILED – Failed attempted abortion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data