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Other disorders of carbohydrate metabolism

DOID EFO Endpoint Browser PheWeb

E4_CARBO

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

172

6. Filter based on genotype QC (FinnGen only)

172

Control definitions (FinnGen only)

Control exclude
E4_METABOLIA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Similar endpoints

↥

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1407 651 742
Only index persons 1083 514 569
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 27.79 35.37 20.72
Only index persons 26.10 32.40 20.41

-FinnGen-

Key figures

All Female Male
Number of individuals 172 81 91
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 24.99 29.17 21.27

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
162
Matched controls
1621
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
27188
ICD-8 Finland
Congenital disorders of carbohydrate metabolism, Alii definiti
+∞
78.7
69
*
E74.0
ICD-10 Finland
Glycogen storage disease
+∞
17.0
16
*
27199
ICD-8 Finland
Congenital disorders of carbohydrate metabolism, Unspecified
+∞
12.7
12
*
E74.1
ICD-10 Finland
Disorders of fructose metabolism
+∞
11.6
11
*
2714A
ICD-9 Finland
Disorders of carbohydrate transport and metabolism, Renal glycosuria
+∞
7.3
7
*
2712A
ICD-9 Finland
Disorders of carbohydrate transport and metabolism, Hereditary fructose intolerance
+∞
7.3
7
*
E74.89
ICD-10 Finland
Other specified disorders of carbohydrate metabolism
+∞
7.3
7
*
Y0599
ICD-8 Finland
Investigation of digestive system
11.7
6.4
11
10
E74.4
ICD-10 Finland
Disorders of pyruvate metabolism and gluconeogenesis
+∞
6.3
6
*
503
Kela drug reimbursment
Inborn metabolic disorders
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
97
578
2.56
8.35
10.4
6.9
mmol/l
1.2
1.2
0.36
79
497
(3013005) Retinol [Moles/volume] in Serum or Plasma
10
6
17.57
6.83
4.3
4.5
umol/l
1.7
1.3
—
10
6
(3024561) Albumin [Mass/volume] in Serum or Plasma
84
501
2.32
6.81
7.7
4.4
g/l
36.1
35.9
0.11
78
473
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
57
288
2.46
6.71
2.1
2.2
mg/l
2.9
3.1
0.25
50
251
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
88
539
2.30
6.66
9.2
6.1
mmol/l
1.2
1.2
0.70
78
500
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
23
75
3.39
6.03
7.6
3.7
ng/l
92.8
77.1
0.34
23
65
(3019309) Folate [Moles/volume] in Red Blood Cells
41
188
2.55
5.86
2.2
1.7
nmol/l
1279.1
1158.2
0.38
30
145
(3009508) Creatinine [Moles/volume] in Urine
61
337
2.26
5.74
4.2
2.9
mmol/l
7.5
8.5
0.82
55
287
(3018418) pH of Serum or Plasma
59
330
2.20
5.33
7.4
3.1
ph
7.4
7.4
0.53
12
64
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
77
479
2.10
5.28
3.9
2.3
nmol/l
73.2
74.8
0.18
72
428
(3048689) Calprotectin [Mass/mass] in Stool
37
170
2.50
5.23
2.3
2.9
ug/g
40.1
83.1
2.97
26
132
(3015377) Calcium [Moles/volume] in Serum or Plasma
66
396
2.08
4.91
4.3
2.9
mmol/l
2.4
2.4
0.13
58
355
(3012516) Albumin [Mass/volume] in Urine
54
301
2.16
4.86
3.8
3.0
mg/l
2563.0
447.6
0.63
36
204
(3021901) Oxygen saturation in Capillary blood
10
20
5.25
4.84
3.7
5.5
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
82
548
1.95
4.40
4.1
2.7
ug/l
162.9
123.1
0.59
76
505
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
7
6
12.08
4.31
2.1
4.7
umol/l
36.4
26.8
—
7
6
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
59
356
2.00
4.22
2.8
2.3
u/l
56.6
55.6
0.11
51
329
(3013650) Neutrophils [#/volume] in Blood by Automated count
104
761
1.93
4.18
11.8
9.4
e9/l
3.5
4.0
1.39
97
666
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
123
953
2.02
4.17
11.0
6.8
u/l
85.2
82.4
0.24
117
892
(3020717) Zinc [Moles/volume] in Serum or Plasma
8
10
8.32
4.10
5.4
1.7
umol/l
13.9
12.7
—
8
10
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
116
884
1.96
4.09
3.4
3.2
u/l
43.2
43.2
0.01
109
836
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
69
444
1.93
4.08
2.4
1.8
pmol/l
97.8
97.8
0.00
43
227
(42870588) Differential panel, method unspecified - Blood
70
453
1.92
4.06
10.6
6.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
67
428
1.93
4.04
4.0
3.1
ng/l
30.2
50.2
0.82
48
273
(3019069) Monocytes/100 leukocytes in Blood
89
629
1.86
3.89
10.1
6.9
%
8.9
8.5
0.59
82
594
(3032080) INR in Blood by Coagulation assay
67
433
1.90
3.87
7.9
7.9
inr
1.0
1.2
3.17
24
114
(3018010) Neutrophils/100 leukocytes in Blood
90
640
1.85
3.84
9.5
6.4
%
54.0
55.6
0.57
84
604
(3019198) Lymphocytes [#/volume] in Blood
94
681
1.84
3.75
9.5
6.4
e9/l
1.8
1.9
0.64
86
608
(3006504) Eosinophils/100 leukocytes in Blood
88
627
1.83
3.69
10.0
6.6
%
3.1
2.9
0.44
81
587
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
66
431
1.86
3.65
3.5
3.2
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
91
660
1.80
3.55
9.6
6.4
e9/l
0.6
0.6
0.01
83
577
(4035726)
21
89
2.55
3.48
1.5
1.4
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
91
664
1.79
3.45
9.6
6.4
e9/l
0.0
0.0
0.93
81
579
(3002030) Lymphocytes/100 leukocytes in Blood
89
646
1.78
3.43
10.2
6.7
%
30.3
29.4
0.32
82
605
(3022096) Basophils/100 leukocytes in Blood
85
609
1.78
3.42
10.3
6.7
%
0.7
0.7
0.08
78
568
(3015235) Bicarbonate [Moles/volume] in Capillary blood
11
32
3.60
3.39
2.7
5.0
mmol/l
24.4
23.7
0.32
11
27
(3021589) Normoblasts [#/volume] in Blood
84
602
1.77
3.36
15.6
9.4
e9/l
0.0
0.0
0.50
71
481
(3020682) Albumin/Creatinine [Ratio] in Urine
50
310
1.86
3.20
5.2
3.7
mg/mmol
21.8
5.8
1.01
34
193
(3014111) Lactate [Moles/volume] in Serum or Plasma
21
93
2.43
3.18
8.2
6.4
mmol/l
2.1
1.3
1.14
21
87
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
14
50
2.96
3.17
2.3
2.1
—
—
—
0
0
(3009343) pH of Capillary blood
22
100
2.38
3.15
7.7
6.0
ph
7.4
7.4
—
6
7
(3041096) Erythrocytes [Presence] in Urine by Automated
52
329
1.83
3.11
3.4
2.9
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
92
687
1.73
3.11
9.7
6.9
e9/l
0.2
0.2
0.61
85
612
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
50
315
1.83
3.03
2.9
3.2
ng/l
6003.3
1201.0
0.58
42
253
(3012544) pH of Venous blood
25
123
2.21
3.00
8.7
4.7
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
25
123
2.21
3.00
8.8
4.5
kpa
5.9
5.8
0.14
25
118
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
22
103
2.30
2.96
7.7
5.8
kpa
4.9
5.2
1.12
22
95
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
10
30
3.48
2.95
1.2
1.4
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
21
97
2.33
2.91
7.8
6.1
mmol/l
0.1
1.8
1.14
16
74
(3042936) Bacteria identified in Isolate by Culture
31
169
2.02
2.87
1.7
2.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
32
177
1.99
2.85
1.3
1.4
titre
880.0
503.4
—
5
29
(1616796) Gas panel - Central venous blood
8
18
4.61
2.83
6.4
4.0
—
—
—
0
0
(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma
5
6
8.53
2.76
1.0
1.2
mg/l
241.4
261.0
—
5
6
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
5
6
8.53
2.76
1.6
1.3
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
20
93
2.30
2.73
5.2
5.7
%
0.0
0.1
—
5
30
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
6
10
6.17
2.72
1.2
1.0
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
11
38
3.02
2.63
3.0
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
51
336
1.74
2.62
7.6
7.0
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
21
103
2.18
2.54
3.1
3.3
g/l
9.8
9.9
0.05
21
95
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
9
26
3.59
2.52
1.8
3.0
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
80
599
1.63
2.52
3.3
3.1
estimate
0.0
0.0
0.00
17
110
(3037467) Urinalysis macro (dipstick) panel - Urine
105
841
1.64
2.51
5.0
3.8
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
20
97
2.20
2.49
5.2
5.6
%
0.2
0.8
—
5
34
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
66
472
1.65
2.49
3.4
3.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
47
308
1.72
2.45
5.6
4.7
—
—
—
0
0
(40767503) Oxygen content in Capillary blood by calculation
7
17
4.24
2.38
4.6
2.9
%
16.2
16.0
—
7
7
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
82
627
1.59
2.31
10.8
6.0
umol/l
13.0
11.8
0.30
75
595
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
6
13
4.74
2.29
7.7
2.0
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
115
955
1.62
2.26
5.0
4.0
mm/h
12.9
11.2
0.57
105
880
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
24
3.44
2.21
1.4
1.5
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
46
308
1.67
2.20
1.7
1.4
u/ml
3.0
1.5
0.37
14
75
(3044889) 12 lead EKG panel
107
877
1.58
2.20
3.4
3.5
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
7
19
3.79
2.17
1.0
2.6
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
46
309
1.67
2.17
3.8
3.6
estimate
0.0
0.0
0.00
18
107
(3009261) Glucose [Presence] in Urine by Test strip
79
607
1.56
2.14
3.4
3.2
estimate
0.0
0.0
0.00
18
111
(40768797) Stomach Pathology biopsy report
29
171
1.84
2.14
1.3
1.2
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
78
599
1.55
2.11
4.4
4.3
estimate
0.0
0.0
0.00
19
108
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
155
0.37
2.02
1.2
1.8
—
—
—
0
0
(4027681)
5
11
4.65
1.95
1.0
1.2
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
6
16
3.84
1.95
4.5
2.9
—
—
—
0
0
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
5
12
4.26
1.83
1.0
1.2
mg/l
226.8
193.5
—
5
12
(3023520) Reticulocytes [#/volume] in Blood
17
88
2.03
1.82
11.8
3.6
e9/l
60.7
66.7
0.23
12
69
(3037756) Immunofixation for Serum or Plasma
7
23
3.13
1.82
1.0
1.7
—
—
—
0
0
(3034860) Kappa light chains.free [Mass/volume] in Serum
7
24
3.00
1.74
1.0
2.4
mg/l
56.2
301.0
—
7
19
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
7
24
3.00
1.74
1.0
2.4
mg/l
34.5
24.7
—
7
19
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
20
112
1.89
1.73
4.0
3.2
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
10
42
2.47
1.71
9.6
1.7
g/l
1.3
1.6
—
10
37
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
112
957
1.49
1.68
4.4
3.7
pmol/l
15.1
14.7
0.86
105
870
(3045424) Erythrocytes [Presence] in Urine
6
19
3.23
1.67
1.5
1.1
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
13
63
2.15
1.64
1.5
2.0
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
132
1170
1.55
1.63
4.9
4.3
mu/l
1.8
1.9
0.89
120
1070
(36304419) Bacteria [Presence] in Urine
47
339
1.53
1.63
3.0
2.9
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
23
139
1.76
1.58
6.6
6.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
34
229
1.60
1.57
1.8
1.9
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
41
289
1.55
1.57
1.3
1.5
g/l
2.0
2.4
0.81
25
165
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
14
72
2.03
1.54
1.7
1.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
51
380
1.49
1.51
3.2
3.0
e6/l
44.0
204.1
0.46
45
294
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
37
2.51
1.50
1.0
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
37
2.51
1.50
1.0
1.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
14
73
2.00
1.48
1.1
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
21
126
1.76
1.48
1.9
1.6
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
136
1223
1.54
1.47
4.2
3.6
mmol/l
1.3
1.3
0.01
127
1119
(3000991) Gas panel - Venous blood
18
103
1.83
1.47
12.7
6.8
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
5
16
3.19
1.45
1.2
1.2
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
16
3.19
1.45
1.0
1.1
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
5
16
3.19
1.45
1.0
1.9
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
6
22
2.79
1.44
3.5
4.7
%
45.5
70.7
—
6
22
(3024928) Oxygen saturation in Venous blood
6
22
2.79
1.44
3.7
6.7
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
57
442
1.43
1.36
3.7
3.4
e6/l
10.1
55.1
2.48
49
310
(3025941) Bacteria identified in Stool by Culture
12
61
2.04
1.36
1.1
1.2
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
11
54
2.11
1.36
3.8
3.7
%
1.2
1.3
0.20
11
54
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
33
229
1.55
1.35
1.5
1.2
iu/ml
11.1
32.8
—
9
80
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
20
122
1.72
1.34
1.5
1.7
—
—
—
0
0
(3022145) Colonoscopy Study observation
22
139
1.67
1.31
1.7
1.3
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
8
34
2.42
1.31
1.3
1.2
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
5
18
2.83
1.29
1.4
1.2
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
15
85
1.84
1.27
1.7
1.9
g/l
1.2
1.5
0.39
15
79
(36660697) Celiac disease serology panel - Serum
20
124
1.69
1.27
1.1
1.1
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
5
19
2.68
1.22
3.8
2.6
mmol/l
1.6
1.6
—
5
19
(3042111) Morphology [Interpretation] in Bone marrow Narrative
5
19
2.68
1.22
1.2
2.5
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
8
38
2.16
1.20
1.0
1.2
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
145
1341
1.52
1.18
24.2
13.3
mmol/l
4.0
4.0
0.11
140
1305
(3030467) Casts [#/volume] in Urine by Automated count
45
343
1.42
1.17
3.1
2.9
e6/l
0.2
0.3
0.32
40
254
(3044640) Blood type and Crossmatch panel - Blood
49
380
1.40
1.16
5.4
2.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
30
2.39
1.13
1.7
1.2
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
8
40
2.05
1.13
1.6
1.7
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
144
1333
1.49
1.13
21.3
12.3
mg/l
26.0
23.1
0.37
116
1021
(3048929) Epstein Barr virus Ab [Presence] in Serum
8
41
2.00
1.10
1.5
1.7
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
21
2.42
1.10
1.2
1.2
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
9
46
2.01
1.05
1.4
1.7
—
—
—
0
0
(3022313) Gas panel - Capillary blood
14
83
1.75
1.05
9.6
5.9
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
30
217
1.46
1.02
1.3
1.2
u/ml
0.9
2.5
—
8
81
(40760892) CBC W Ordered Manual Differential panel - Blood
38
288
1.41
1.02
5.6
5.6
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
23
158
1.53
1.00
1.8
1.7
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
23
2.21
0.98
1.0
1.7
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
23
2.21
0.98
6.2
4.7
e9/l
2.7
4.1
—
5
23
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
5
23
2.21
0.98
1.6
1.8
—
88.1
—
0
5
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
8
142
0.54
0.98
1.3
1.8
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
31
0.00
0.97
0.0
1.3
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
139
1290
1.40
0.96
5.1
4.3
mmol/l
2.7
2.8
0.55
131
1191
(3021879) Hepatitis B virus core Ab [Presence] in Serum
12
70
1.77
0.95
1.5
1.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
12
70
1.77
0.95
1.8
1.8
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
28
204
1.44
0.93
2.6
3.1
ng/l
9.2
362.9
1.51
20
150
(40761511) CBC panel - Blood by Automated count
150
1414
1.48
0.91
20.0
10.8
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
15
95
1.63
0.91
4.2
4.1
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
8
43
1.90
0.88
1.4
3.8
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
8
43
1.90
0.88
1.6
1.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
165
0.58
0.87
1.3
2.0
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
136
1268
1.35
0.82
4.8
3.9
mmol/l
1.5
1.4
0.38
128
1170
(3045414) Leukocytes [Presence] in Urine
8
47
1.74
0.82
1.4
1.7
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
12
74
1.67
0.80
2.2
3.6
ng/l
187.8
134.6
0.21
12
66
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
35
273
1.35
0.80
3.0
1.9
mg/l
1.6
0.9
0.30
28
208
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
8
48
1.70
0.80
3.8
3.6
%
41.5
50.2
—
8
48
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
25
0.00
0.79
0.0
1.3
—
—
—
0
0
(3002256) Pathology report gross observation
21
150
1.46
0.78
1.2
1.2
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
24
2.11
0.75
6.4
5.7
%
46.0
56.2
—
5
24
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
136
1274
1.32
0.75
4.7
3.9
mmol/l
4.7
4.7
0.11
128
1187
(40761535) Cells panel - Urine sediment
14
93
1.55
0.72
4.0
3.5
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
5
26
1.95
0.71
1.0
1.3
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5
26
1.95
0.71
1.4
1.8
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
5
26
1.95
0.71
1.0
2.3
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
21
154
1.41
0.69
3.8
4.1
umol/l
11.5
8.4
0.31
16
133
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
22
163
1.40
0.68
1.1
1.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
132
1238
1.28
0.67
5.0
4.0
mmol/l
6.1
5.9
0.91
120
1135
(1761482) Bacteria [#/volume] in Urine by Culture
5
28
1.81
0.66
3.8
3.0
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
22
165
1.38
0.64
4.8
2.4
s
29.7
29.1
0.20
22
160
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
29
1.75
0.64
1.2
1.2
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
14
96
1.50
0.64
16.1
8.1
mmol/l
23.8
25.4
1.24
14
96
(40768804) Tissue Pathology biopsy report
55
471
1.25
0.63
2.1
2.0
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
30
1.69
0.62
1.0
1.3
—
—
—
0
0
(3047181) Lactate [Moles/volume] in Blood
5
30
1.69
0.62
3.0
19.6
mmol/l
1.6
1.1
—
5
24
(3000492) Spirometry study
19
140
1.40
0.61
1.4
1.4
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
8
52
1.56
0.60
1.6
2.2
u/l
51.1
39.0
—
8
47
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
124
1161
1.24
0.60
7.1
4.9
mmol/mol
40.2
39.3
0.43
115
1085
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
36
1.69
0.57
3.3
2.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
6
36
1.69
0.57
1.7
1.3
—
—
—
0
0
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
6
36
1.69
0.57
2.8
3.3
u/ml
5.2
101.0
—
6
30
(3026008) Bacteria identified in Urine by Culture
38
316
1.26
0.56
3.5
2.6
—
—
—
0
0
(3008152) Bicarbonate [Moles/volume] in Arterial blood
9
65
1.41
0.51
2.9
13.4
mmol/l
22.1
24.4
—
9
59
(3000494) Fungus identified in Specimen by Culture
19
147
1.33
0.47
1.8
1.5
—
—
—
0
0
(3013512) EKG study
39
333
1.22
0.46
4.2
3.3
—
—
—
0
0
(40768443) Skin Pathology biopsy report
7
50
1.42
0.45
1.0
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
64
574
1.18
0.45
6.3
3.9
—
—
—
0
0
(3019225) pH of Specimen
14
104
1.38
0.44
7.7
3.8
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
15
113
1.36
0.44
4.6
10.3
mmol/l
0.4
1.4
—
10
86
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
31
1.63
0.43
1.0
1.6
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
156
1515
1.32
0.43
30.0
17.7
e9/l
6.4
6.6
1.01
151
1468
(3001019) Free T4 and TSH panel - Serum or Plasma
8
57
1.42
0.43
1.4
1.4
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
33
1.53
0.41
1.0
1.9
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
0
16
0.00
0.41
0.0
3.6
—
11.3
—
0
5
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
5
34
1.48
0.40
1.0
1.9
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
33
281
1.22
0.40
2.8
3.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
32
272
1.22
0.40
1.4
1.7
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
134
1285
1.19
0.39
21.6
12.7
%
39.0
40.4
0.99
101
1013
(3019060) Gas panel - Arterial blood
9
71
1.28
0.37
2.1
9.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
40
356
1.16
0.31
1.4
1.4
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
49
446
1.14
0.28
3.3
4.1
ug/l
1.7
2.6
0.63
44
397
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
8
66
1.22
0.27
2.1
3.4
pmol/l
4.3
4.6
—
8
57
(3013139) Helicobacter pylori Ag [Presence] in Stool
9
72
1.26
0.26
1.4
1.2
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
17
142
1.22
0.26
4.8
3.9
%
31.2
30.8
0.04
11
93
(3027801) Oxygen [Partial pressure] in Arterial blood
14
115
1.24
0.24
4.4
10.2
kpa
12.1
12.3
0.06
14
110
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
14
115
1.24
0.24
4.4
10.2
kpa
4.8
5.2
0.96
14
109
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
98
936
1.11
0.24
3.0
3.3
—
—
—
0
0
(4010399)
13
106
1.24
0.24
1.5
1.5
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
37
1.36
0.23
1.0
1.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
19
163
1.19
0.22
1.4
1.6
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
32
354
0.88
0.22
3.2
3.6
%
20.3
21.5
—
9
152
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.8
—
13.1
—
0
10
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
24.6
—
1569.4
—
0
12
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
16.7
—
886.1
—
0
12
(4062490)
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
2.8
—
33.0
—
0
13
(3051611) Lipemic interference index of Serum or Plasma
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(4306422)
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
49
1.23
0.20
8.3
17.9
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
12
99
1.23
0.20
1.9
2.3
e9/l
3.5
4.2
—
6
81
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
121
1178
1.09
0.17
20.4
10.9
ml/min/173m2
84.3
84.0
0.04
106
958
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
129
0.84
0.15
1.8
1.8
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
23
208
1.12
0.15
2.2
2.6
e6/l
2.1
0.9
0.36
13
116
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
32
301
1.08
0.10
6.5
2.2
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
44
1.14
0.10
1.2
2.7
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
10
87
1.16
0.09
1.2
1.2
iu/ml
91.6
136.7
—
5
35
(3009214) Lutropin [Units/volume] in Serum or Plasma
5
47
1.07
0.09
2.8
1.8
u/l
2.9
8.0
—
5
38
(3014007) Fractional oxyhemoglobin in Arterial blood
5
60
0.83
0.08
10.0
7.3
%
96.1
93.5
—
5
60
(3008898) HLA-B27 [Presence]
7
65
1.08
0.08
1.1
1.0
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
8
76
1.06
0.07
2.6
1.7
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
8
77
1.04
0.07
1.0
1.0
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
21
197
1.08
0.06
2.8
2.7
e6/l
1.6
1.8
0.06
11
105
(1761868) Lipid panel - Serum or Plasma
53
515
1.04
0.06
3.1
2.5
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
19
182
1.05
0.02
1.6
1.4
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
12
126
0.95
0.00
1.8
1.8
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
11
109
1.01
0.00
1.5
1.6
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
19
187
1.02
0.00
1.6
1.9
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016038) Potassium [Moles/volume] in Urine
0
7
0.00
0.00
0.0
3.4
—
42.9
—
0
7
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
5
57
0.87
0.00
1.0
1.3
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
27
270
1.00
0.00
1.7
2.8
ug/l
0.5
0.7
1.06
15
163
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
5
58
0.86
0.00
1.0
1.3
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3027901) Hemoglobin [Mass/volume] in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
174.2
—
0
6
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
15
150
1.00
0.00
1.2
1.4
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
6
62
0.97
0.00
3.2
1.6
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(4198724)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
5
52
0.96
0.00
2.4
2.7
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022670) pH of Venous cord blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4024509)
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
8
86
0.93
0.00
5.4
2.7
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
5
58
0.86
0.00
1.0
1.3
—
—
—
0
0
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758292) HTLV I+II Ab panel - Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
1.2
—
0
5
(21491868) Cryoglobulin [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.7
—
18.7
—
0
6
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
7
74
0.94
0.00
2.1
1.7
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035880) pH of Pleural fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_CARBO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_CARBO.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: E4_CARBO – Other disorders of carbohydrate metabolism

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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