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Disorder of carbohydrate metabolism, other/unspecified

DOID EFO Endpoint Browser PheWeb

E4_CARBONAS

renal glycosuria: An autosomal inherited disorder due to defective reabsorption of GLUCOSE by the PROXIMAL RENAL TUBULES. The urinary loss of glucose can reach beyond 50 g/day. It is attributed to the mutations in the SODIUM-GLUCOSE TRANSPORTER 2 encoded by the SLC5A2 gene.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E74.80, E74.89, E74.9
  • Hospital discharge: ICD-9 — 271[4-9]
  • Hospital discharge: ICD-8 — 271[8-9]
  • Cause of death: ICD-10 — E74.80, E74.89, E74.9
  • Cause of death: ICD-9 — 271[4-9]
  • Cause of death: ICD-8 — 271[8-9]

2 out of 7 registries used, show all original rules.

118

4. Check minimum number of events

None

118

5. Include endpoints

None

118

6. Filter based on genotype QC (FinnGen only)

118

Control definitions (FinnGen only)

Control exclude
E4_METABOLIA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 944 427 508
Only index persons 762 350 412
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.02
Median age at first event (years)
Whole population 27.25 34.74 20.56
Only index persons 25.83 32.23 20.38

-FinnGen-

Key figures

All Female Male
Number of individuals 118 51 67
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 23.86 28.29 20.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
111
Matched controls
1111
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
27188
ICD-8 Finland
Congenital disorders of carbohydrate metabolism, Alii definiti
+∞
83.0
69
*
27199
ICD-8 Finland
Congenital disorders of carbohydrate metabolism, Unspecified
+∞
12.7
12
*
E74.89
ICD-10 Finland
Other specified disorders of carbohydrate metabolism
+∞
7.4
7
*
2714A
ICD-9 Finland
Disorders of carbohydrate transport and metabolism, Renal glycosuria
+∞
7.4
7
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
64
366
2.64
6.26
5.9
6.8
mmol/l
1.2
1.2
0.34
57
344
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
67
395
2.61
6.11
7.3
7.3
mmol/l
1.2
1.2
0.28
53
341
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
16
47
3.78
4.95
5.4
3.9
ng/l
71.2
86.8
0.35
16
40
(3018418) pH of Serum or Plasma
43
223
2.46
4.93
5.2
3.4
ph
7.4
7.4
—
10
41
(3006504) Eosinophils/100 leukocytes in Blood
63
408
2.17
4.11
7.2
6.0
%
3.4
3.1
0.55
58
383
(3024561) Albumin [Mass/volume] in Serum or Plasma
56
349
2.15
4.00
7.5
4.3
g/l
35.8
35.8
0.00
51
329
(3019069) Monocytes/100 leukocytes in Blood
63
411
2.14
4.00
7.4
6.4
%
9.1
8.5
0.76
58
389
(3022096) Basophils/100 leukocytes in Blood
61
396
2.12
3.90
7.5
6.1
%
0.7
0.7
0.22
56
370
(3048689) Calprotectin [Mass/mass] in Stool
25
112
2.56
3.81
2.4
2.7
ug/g
48.9
85.5
1.48
16
89
(3001604) Monocytes [#/volume] in Blood
64
431
2.06
3.63
6.8
6.1
e9/l
0.6
0.6
0.31
59
379
(3006315) Basophils [#/volume] in Blood
64
433
2.04
3.56
7.0
6.1
e9/l
0.0
0.0
0.52
59
381
(3019309) Folate [Moles/volume] in Red Blood Cells
27
130
2.40
3.53
2.0
1.7
nmol/l
1360.8
1228.7
0.28
20
99
(3002030) Lymphocytes/100 leukocytes in Blood
63
425
2.03
3.52
7.5
6.2
%
29.8
29.6
0.06
58
398
(3028626) Oxygen [Partial pressure] in Capillary blood
11
32
3.69
3.42
5.1
9.2
kpa
9.4
9.1
0.24
11
32
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
42
249
2.07
3.30
2.6
2.3
u/l
60.5
53.9
0.85
34
231
(3041096) Erythrocytes [Presence] in Urine by Automated
39
226
2.08
3.25
3.5
2.6
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
7
11
6.68
3.23
3.4
3.3
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
44
270
2.00
3.13
4.7
3.1
mmol/l
2.4
2.4
0.15
39
243
(42870588) Differential panel, method unspecified - Blood
47
297
1.97
3.06
7.8
5.6
—
—
—
0
0
(4035726)
15
62
2.63
2.66
1.5
1.4
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
9
25
3.81
2.63
3.4
1.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
46
301
1.87
2.63
2.2
1.8
pmol/l
102.2
99.4
0.14
28
156
(3029937) Albumin [Presence] in Urine by Test strip
34
201
1.97
2.63
3.5
3.6
estimate
0.0
0.0
0.00
13
67
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
34
202
1.96
2.59
1.7
1.3
u/ml
3.4
1.8
0.33
12
50
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
26
3.66
2.54
1.0
1.1
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
26
3.66
2.54
1.0
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
48
323
1.82
2.49
3.3
3.0
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
51
352
1.79
2.42
2.7
2.5
ug/l
131.0
127.8
0.05
46
320
(3009343) pH of Capillary blood
14
59
2.56
2.40
5.3
7.0
ph
7.4
7.4
—
5
5
(1616796) Gas panel - Central venous blood
5
8
6.46
2.39
9.0
7.3
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
5
8
6.46
2.39
6.2
1.9
umol/l
13.6
11.6
—
5
8
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
117
2.08
2.25
1.5
2.0
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
56
404
1.73
2.24
14.4
8.5
e9/l
0.0
0.0
0.44
48
323
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
43
288
1.78
2.22
3.2
2.9
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
23
126
2.03
2.17
1.3
1.3
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
11
45
2.59
1.99
1.1
1.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
56
414
1.67
1.99
3.4
3.0
estimate
0.0
0.0
0.00
12
72
(3035350) Ketones [Presence] in Urine by Test strip
55
405
1.67
1.98
3.3
2.9
estimate
0.0
0.0
0.00
12
73
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
8
27
3.10
1.97
1.0
1.1
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
55
407
1.66
1.93
4.5
4.0
estimate
0.0
0.0
0.00
13
69
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
7
22
3.31
1.91
1.3
1.3
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
15
73
2.21
1.90
4.3
2.2
u/l
34.1
29.8
0.19
15
56
(3013707) Erythrocyte sedimentation rate by Westergren method
79
645
1.68
1.86
4.9
3.9
mm/h
9.9
10.8
0.27
71
598
(40767503) Oxygen content in Capillary blood by calculation
5
12
4.30
1.84
5.4
3.3
%
17.1
14.9
—
5
5
(3004716) Salmonella sp identified in Stool by Organism specific culture
11
48
2.42
1.76
1.1
1.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
21
121
1.89
1.72
1.9
2.6
—
—
—
0
0
(3022145) Colonoscopy Study observation
17
91
2.01
1.71
1.6
1.3
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
42
299
1.63
1.67
4.3
3.1
ng/l
24.0
59.3
1.24
32
191
(3032080) INR in Blood by Coagulation assay
41
293
1.61
1.60
4.5
8.4
inr
1.1
1.2
2.08
15
75
(3015736) pH of Urine
42
304
1.59
1.55
2.6
2.8
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
31
210
1.65
1.48
3.6
2.9
mg/l
2476.9
344.7
0.40
20
140
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
91
792
1.65
1.47
4.4
4.3
mu/l
1.7
1.9
1.21
84
727
(3037467) Urinalysis macro (dipstick) panel - Urine
69
565
1.53
1.45
5.0
3.5
—
—
—
0
0
(40758558) Short blood count panel - Blood
33
230
1.60
1.41
6.7
6.5
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
28
188
1.64
1.38
1.3
1.5
g/l
2.1
2.6
0.79
14
110
(3017143) Hepatitis C virus Ab [Presence] in Serum
14
76
1.96
1.36
1.4
1.6
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
116
0.41
1.34
1.2
2.0
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
39
286
1.54
1.34
3.5
3.2
e6/l
11.4
51.9
1.66
34
204
(3044640) Blood type and Crossmatch panel - Blood
35
251
1.56
1.32
2.6
2.2
—
—
—
0
0
(3044889) 12 lead EKG panel
74
623
1.50
1.30
3.5
3.5
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
42
315
1.52
1.30
2.1
2.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
12
63
2.01
1.28
4.5
3.6
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
15
86
1.85
1.26
1.3
1.6
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
6
25
2.47
1.26
1.7
1.1
—
—
—
0
0
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
6
25
2.47
1.26
2.8
2.8
u/ml
5.2
97.2
—
6
20
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
14
80
1.85
1.19
1.6
1.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
29
204
1.56
1.18
6.6
4.9
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
8
39
2.13
1.18
1.1
1.5
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
5
20
2.56
1.16
1.2
1.2
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
20
2.56
1.16
1.4
1.6
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
27
188
1.57
1.15
4.9
5.4
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
7
30
2.42
1.14
1.9
1.9
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
75
643
1.46
1.14
3.1
3.3
u/l
47.9
43.6
0.32
70
610
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
6
121
0.47
1.13
1.2
2.0
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
13
74
1.85
1.12
3.5
3.4
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
30
217
1.51
1.08
5.0
3.5
mg/mmol
7.8
5.6
0.13
21
141
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
22
2.33
1.04
1.4
1.9
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
30
220
1.49
1.01
2.9
2.7
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
54
444
1.40
0.99
7.8
5.8
umol/l
13.3
11.6
0.42
48
420
(3045414) Leukocytes [Presence] in Urine
6
28
2.20
0.93
1.0
1.5
—
—
—
0
0
(3000991) Gas panel - Venous blood
11
64
1.79
0.89
5.7
7.5
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
26
190
1.47
0.89
1.9
1.8
mg/l
0.7
0.8
0.28
20
145
(3005719) IgG [Mass/volume] in Serum or Plasma
12
72
1.74
0.89
3.8
2.6
g/l
10.5
10.3
0.06
12
65
(36660697) Celiac disease serology panel - Serum
13
80
1.70
0.89
1.0
1.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
23
165
1.49
0.86
1.6
1.3
iu/ml
12.7
27.6
—
7
57
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
95
871
1.47
0.86
3.9
3.7
mmol/l
1.3
1.4
0.22
88
790
(3000494) Fungus identified in Specimen by Culture
15
98
1.61
0.83
1.3
1.6
—
—
—
0
0
(3022313) Gas panel - Capillary blood
8
48
1.71
0.80
6.4
7.4
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
23
2.22
0.77
1.0
1.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
7
38
1.89
0.75
1.6
2.3
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
98
912
1.44
0.73
4.8
4.5
mmol/l
2.8
2.8
0.24
92
840
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
5
26
1.96
0.71
1.0
1.8
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
99
925
1.44
0.70
18.9
11.9
mg/l
21.6
23.9
0.26
78
712
(3049717) Cytology report of Urine Cyto stain
5
28
1.82
0.67
1.2
2.0
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
29
230
1.35
0.64
1.2
1.4
—
—
—
0
0
(3012544) pH of Venous blood
12
80
1.56
0.62
5.9
3.8
—
—
—
0
0
(3000492) Spirometry study
14
97
1.50
0.62
1.5
1.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
51
1.61
0.62
2.0
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
45
383
1.28
0.60
4.0
3.9
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
8
53
1.55
0.60
1.9
1.6
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
6
36
1.70
0.57
3.0
2.7
e6/l
0.4
0.1
—
6
36
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
59
1.57
0.56
13.0
9.5
mmol/l
23.7
25.4
—
9
59
(3001019) Free T4 and TSH panel - Serum or Plasma
6
38
1.61
0.55
1.5
1.4
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
14
100
1.45
0.55
1.0
1.7
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
6
39
1.57
0.54
1.5
1.5
iu/l
32.4
27.5
—
6
28
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
14
101
1.44
0.52
2.9
7.2
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
18
138
1.36
0.49
2.9
3.2
ng/l
8.1
428.1
1.09
13
100
(3008152) Bicarbonate [Moles/volume] in Arterial blood
7
47
1.52
0.48
2.4
15.1
mmol/l
21.7
24.4
—
7
41
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
7
49
1.46
0.47
2.1
3.2
pmol/l
4.3
4.5
—
7
41
(40761511) CBC panel - Blood by Automated count
102
974
1.35
0.46
18.5
10.6
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
95
901
1.28
0.44
4.5
4.0
mmol/l
1.5
1.4
0.40
89
828
(3009542) Hematocrit [Volume Fraction] of Blood
93
880
1.27
0.43
16.6
12.4
%
40.4
40.5
0.06
73
687
(3028026) IgM [Mass/volume] in Serum or Plasma
8
58
1.41
0.42
2.0
1.7
g/l
1.3
1.5
—
8
52
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
8
60
1.36
0.41
5.4
2.3
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
17
0.00
0.41
0.0
1.4
—
51.4
—
0
17
(40768443) Skin Pathology biopsy report
5
34
1.49
0.41
1.0
1.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
21
170
1.29
0.41
1.4
1.6
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(3002256) Pathology report gross observation
13
98
1.37
0.39
1.1
1.2
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
19
153
1.29
0.38
1.4
1.3
u/ml
0.8
2.9
—
6
62
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
87
822
1.22
0.38
19.0
10.8
ml/min/173m2
83.3
82.9
0.06
78
676
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
87
823
1.22
0.37
6.5
4.8
mmol/mol
40.9
39.2
0.73
80
770
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
109
1.32
0.35
1.7
1.4
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
94
903
1.20
0.29
4.5
4.1
mmol/l
4.7
4.7
0.31
88
836
(40761535) Cells panel - Urine sediment
8
66
1.23
0.27
2.5
3.3
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
10
77
1.33
0.27
2.2
12.7
mmol/l
1.0
1.4
—
5
59
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
74
0.66
0.27
1.4
1.8
—
—
—
0
0
(3019225) pH of Specimen
9
73
1.25
0.26
4.7
3.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
22
190
1.19
0.25
2.5
3.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
85
0.69
0.25
1.5
1.9
—
—
—
0
0
(3008898) HLA-B27 [Presence]
5
38
1.33
0.23
1.2
1.0
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
24
271
0.86
0.23
2.8
3.5
%
19.3
22.1
—
7
116
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
10
0.00
0.21
0.0
3.1
—
24.6
—
0
10
(3050129) First trimester maternal screen panel - Serum or Plasma
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(4062490)
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
6
51
1.19
0.19
2.3
3.0
ng/l
52.5
103.2
—
6
45
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
89
861
1.14
0.19
4.9
4.1
mmol/l
6.2
5.8
1.06
81
795
(21494755) Public health laboratory ask at order entry panel
14
119
1.20
0.18
1.2
1.4
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
36
334
1.11
0.16
3.0
3.8
ug/l
1.5
1.8
0.71
31
302
(1761868) Lipid panel - Serum or Plasma
36
385
0.91
0.15
3.0
2.5
—
—
—
0
0
(3013512) EKG study
26
239
1.11
0.13
4.6
3.3
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
14
125
1.14
0.10
2.6
2.7
e6/l
1.9
1.8
—
9
63
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
53
1.14
0.09
1.0
1.0
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
15
136
1.12
0.09
1.8
2.5
e6/l
2.0
0.9
—
10
74
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
22
205
1.09
0.08
1.9
2.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
61
620
0.97
0.03
2.7
3.3
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
10
108
0.92
0.03
4.0
2.3
s
31.9
28.7
—
10
103
(3026008) Bacteria identified in Urine by Culture
21
208
1.01
0.00
4.7
2.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
12
117
1.03
0.00
1.4
1.6
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
21
207
1.02
0.00
1.9
2.7
ug/l
0.5
0.7
1.67
12
120
(3011648) Oxygen content in Venous blood
0
5
0.00
0.00
0.0
1.0
—
13.7
—
0
5
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
8
79
1.01
0.00
1.7
12.4
kpa
4.9
5.2
—
8
73
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
50
1.00
0.00
1.8
1.1
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3017704) Immunofixation for Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
1392.0
—
0
5
(4024509)
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022670) pH of Venous cord blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
8
79
1.01
0.00
1.7
12.5
kpa
12.1
11.5
—
8
74
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
9
0.00
0.00
0.0
2.4
—
13.7
—
0
9
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.0
—
0.6
—
0
6
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(4010399)
7
78
0.89
0.00
1.4
1.5
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
11.5
—
0
6
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3027901) Hemoglobin [Mass/volume] in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
174.2
—
0
6
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
5
51
0.98
0.00
2.2
12.4
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
6
63
0.95
0.00
1.7
1.1
u/ml
173.7
468.1
—
6
56
(3029075) Extractable nuclear Ab panel - Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
18.6
—
903.7
—
0
7
(3009991) Angiotensin converting enzyme [Enzymatic activity/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
1.0
—
0
6
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
20.3
—
1631.3
—
0
7
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(4306422)
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
56
0.89
0.00
1.6
1.6
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.7
—
1.0
—
0
9

Mortality – FinRegistry

↥

Association

Association between endpoint E4_CARBONAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_CARBONAS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: E4_CARBONAS – Disorder of carbohydrate metabolism, other/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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