Benign neoplasm of urinary organs

CD2_BENIGN_URINARY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D30
  • Cause of death: ICD-10 D30

2 out of 7 registries used, show all original rules.

1501

4. Check minimum number of events

None

1501

5. Include endpoints

1668

6. Filter based on genotype QC (FinnGen only)

1668

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum urinariorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10630 5830 4676
Only index persons 8788 5122 3666
Unadjusted period prevalence (%)
Whole population 0.15 0.17 0.13
Only index persons 0.17 0.19 0.14
Median age at first event (years)
Whole population 62.94 61.07 65.27
Only index persons 61.73 59.80 64.43

-FinnGen-

Key figures

All Female Male
Number of individuals 1668 931 737
Unadjusted period prevalence (%) 0.32 0.32 0.32
Median age at first event (years) 61.61 57.81 66.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1480
Matched controls
14794
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
43.7
323.0
452
147
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
16384.0
323.0
977
*
D30.3
ICD-10 Finland
Benign neoplasm: Bladder
+∞
256.9
239
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
18.3
136.7
218
138
UKC02
NOMESCO Finland
Cystoscopy
4.4
118.2
528
1645
KAD00
NOMESCO Finland
Partial nephrectomy
61.3
88.3
103
18
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.0
71.8
149
163
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
54.7
61.5
73
14
KA1AE
NOMESCO Finland
Kidney ultrasound examination
9.3
61.0
131
152
R31
ICD-10 Finland
Unspecified haematuria
3.5
50.7
274
913
KAC10
NOMESCO Finland
Total nephrectomy with capsule
16.4
49.7
81
52
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
13.2
47.6
85
68
D30.1
ICD-10 Finland
Benign neoplasm: Renal pelvis
+∞
46.1
44
*
D30.9
ICD-10 Finland
Benign neoplasm: Urinary organ, unspecified
+∞
46.1
44
*
D30.4
ICD-10 Finland
Benign neoplasm: Urethra
+∞
42.9
41
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
23.6
41.2
59
26
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
39.8
38
*
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
7.6
39.0
94
131
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
7.3
36.9
91
131
2233A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Bladder
+∞
36.6
35
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
35.7
476
2634
PC5DT
NOMESCO Finland
Embolisation of tumor of kidney
+∞
31.4
30
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
31.3
559
3449
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
13.2
31.3
55
43
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
10.7
30.8
60
58
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
29.7
144
434
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
29.2
262
1180
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.3
29.0
111
271
N28.1
ICD-10 Finland
Cyst of kidney
8.4
28.7
64
79
N02BE01
ATC
paracetamol; systemic, rectal
2.3
28.6
1285
11000
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
28.4
130
373
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
7.3
27.6
67
95
22330
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Bladder
+∞
27.2
26
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
25.3
680
4741
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
10.5
24.6
48
47
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
6.3
23.6
64
106
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
23.0
208
931
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
22.8
156
594
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
7.4
22.6
54
75
22300
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
20.9
20
*
J01MA02
ATC
ciprofloxacin; systemic
1.7
20.8
604
4233
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
7.8
20.4
47
62
7323
FHL
Electrosection of TU bladder wall change
27.4
20.1
27
10
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
7.5
20.0
47
64
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
20.0
188
858
B01AB05
ATC
enoxaparin; parenteral
1.8
19.8
472
3102
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
19.6
329
1918
KAC00
NOMESCO Finland
Nephrectomy
21.9
19.5
28
13
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
8.3
19.5
43
53
J01DB01
ATC
cefalexin; oral
1.8
19.4
1164
9958
D30.2
ICD-10 Finland
Benign neoplasm: Ureter
+∞
18.8
18
*
PC5ET
NOMESCO Finland
Extensive embolisation of tumor of kidney
+∞
18.8
18
*
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
8.5
18.5
40
48
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
12.0
18.3
33
28
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
22.0
18.2
26
12
XKD00
NOMESCO Finland
Uroflowmetry
2.0
18.1
278
1565
22388
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Other specified sites
+∞
17.7
17
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
17.6
126
493
1530
FHL
Urethrocystoscopy
4.5
17.4
62
142
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
7.7
16.9
39
52
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
16.6
661
4955
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.4
16.5
80
242
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
15.9
895
7275
8120/1-C67.9
ICD-O-3
Urothelial papilloma, NOS, of bladder, NOS
+∞
15.6
15
*
A02BC02
ATC
pantoprazole; systemic
1.6
15.1
942
7805
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
15.1
223
1232
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
14.7
243
1398
A02BC05
ATC
esomeprazole; systemic
1.6
14.7
574
4241
KAC20
NOMESCO Finland
Nephroureterectomy
80.9
14.6
16
*
UJF32
NOMESCO Finland
Coloscopy
1.7
14.4
396
2666
G04CA02
ATC
tamsulosin; oral
1.7
14.1
357
2348
7321
FHL
TU biopsy, coagulation or laser
12.8
13.9
24
19
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
13.6
315
2015
JN4BD
NOMESCO Finland
Extensive body CT
2.0
13.6
191
1032
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.0
13.5
53
135
WX320
NOMESCO Finland
Spinalanesthesy
1.7
13.4
340
2232
U14
ICPC
Kidney symptom/complaint
4.9
13.3
43
90
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
13.2
437
3079
8260/3-C64.9
ICD-O-3
Papillary adenocarcinoma, NOS, of kidney, NOS
15.2
13.1
21
14
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
13.0
201
1125
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
6.2
12.6
33
54
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
70.4
12.6
14
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
12.5
274
1722
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
12.2
126
599
UKB02
NOMESCO Finland
Retrograde ureteroscopy
5.8
12.0
33
58
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
12.0
283
1815
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
7.1
11.8
28
40
WX110
NOMESCO Finland
Local anesthesy
1.5
11.5
894
7530
D30.7
ICD-10 Finland
Benign neoplasm: Other urinary organs
+∞
11.5
11
*
KH1AD
NOMESCO Finland
CT of urinary organs
3.1
11.3
60
197
J01EA01
ATC
trimethoprim; systemic
1.6
11.2
376
2638
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
14.0
11.0
18
13
ZXA00
NOMESCO Finland
Right side
1.5
10.9
402
2880
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.4
10.9
51
152
R4110
NOMESCO Finland
Physiotherapy
1.6
10.8
375
2648
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
13.0
10.6
18
14
P01AB01
ATC
metronidazole; oral, rectal
1.5
10.6
528
4044
A02BC03
ATC
lansoprazole; oral
1.5
10.2
422
3097
JN4AD
NOMESCO Finland
Body CT examination
2.0
9.9
120
612
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
9.8
466
3518
N20.1
ICD-10 Finland
Calculus of ureter
2.7
9.8
66
253
R50.9
ICD-10 Finland
Fever, unspecified
1.7
9.7
194
1178
WX402
NOMESCO Finland
General anaesthesia
1.7
9.7
210
1310
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
9.6
312
2162
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
9.4
170
1001
U07
ICPC
Urine symptom/complaint other
2.2
9.4
95
446
8130/1-C67.9
ICD-O-3
Papillary urothelial neoplasm of low malignant potential of bladder, NOS
30.2
9.4
12
*
PC5SC
NOMESCO Finland
Selective angiography of kidney artery with X-ray
30.2
9.4
12
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
9.4
126
670
KCB00
NOMESCO Finland
Biopsy of bladder
8.7
9.3
19
22
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
9.3
92
431
R33
ICD-10 Finland
Retention of urine
1.9
9.2
128
687
7125
FHL
Nephrectomy (extrrafascial)
13.8
9.2
15
11
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
9.0
223
1443
J01MA12
ATC
levofloxacin; systemic
1.6
9.0
272
1850
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
5.1
9.0
27
54
S18
ICPC
Laceration/cut
1.4
8.9
587
4703
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.7
286
1981
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.5
208
1336
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.5
530
4193
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
8.5
426
3232
KA3LT
NOMESCO Finland
Njurlesion coagulation
20.1
8.5
12
6
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.4
344
2503
18899
ICD-8 Finland
Malignant neoplasm of bladder
90.5
8.4
9
*
22399
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Unspecified site
+∞
8.3
8
*
JN4CD
NOMESCO Finland
Very extensive body CT
2.3
8.3
72
315
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
9.5
8.3
16
17
ZXA05
NOMESCO Finland
Left side
1.5
8.1
372
2767
5997A
ICD-9 Finland
Other disorders of urethra and urinary tract, Haematuria
8.2
8.1
17
21
U79
ICPC
Neoplasm urinary tract unspecified
33.5
8.1
10
*
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
6.9
8.1
19
28
C67.4
ICD-10 Finland
Malignant neoplasm: Posterior wall of bladder
22.1
8.0
11
5
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.7
7.9
153
923
B01AB10
ATC
tinzaparin; parenteral
1.9
7.8
107
574
C08CA01
ATC
amlodipine; oral
1.4
7.7
514
4101
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
18.4
7.6
11
6
D01
ICPC
Abdominal pain/cramps general
1.8
7.5
134
788
1888X
ICD-9 Finland
Malignant neoplasm of bladder, Other specified sites of bladder
13.4
7.4
12
9
C67.1
ICD-10 Finland
Malignant neoplasm: Dome of bladder
13.4
7.4
12
9
D02
ICPC
Abdominal pain epigastric
2.1
7.4
79
385
N03AX16
ATC
pregabalin; oral
1.5
7.4
309
2253
R35
ICD-10 Finland
Polyuria
2.0
7.3
95
500
R30.0
ICD-10 Finland
Dysuria
2.4
7.3
57
239
N18.8
ICD-10 Finland
Other chronic renal failure
2.7
7.2
47
178
M54.5
ICD-10 Finland
Low back pain
1.4
7.2
399
3069
KED22
NOMESCO Finland
Transurethral resection of prostate
2.0
7.2
93
491
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.2
587
4826
Q85.1
ICD-10 Finland
Tuberous sclerosis
30.1
7.1
9
*
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
20.1
7.1
10
5
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.1
281
2024
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
2.9
7.0
40
139
N20.0
ICD-10 Finland
Calculus of kidney
3.0
6.9
37
125
G04CA01
ATC
alfuzosin; oral
1.6
6.9
160
1014
C64.80
ICD-10 Finland
Wilms tumour
13.8
6.9
11
8
J01MA06
ATC
norfloxacin; oral
1.6
6.9
187
1238
C07AB07
ATC
bisoprolol; oral
1.3
6.8
670
5654
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.7
204
1386
KB1CG
NOMESCO Finland
Extensive MRI examination of urinary tract with high intensity magnet
22.6
6.7
9
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.5
6.6
48
195
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.6
143
890
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.7
6.5
118
698
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
6.4
290
2146
N30.0
ICD-10 Finland
Acute cystitis
1.6
6.3
181
1209
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.3
364
2812
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.3
195
1332
205
Kela drug reimbursment
Chronic hypertension
1.4
6.2
418
3310
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
6.2
265
1936
J01CA04
ATC
amoxicillin; systemic
1.3
6.1
1051
9560
H02AB06
ATC
prednisolone; systemic
1.3
6.1
617
5197
D06
ICPC
Abdominal pain localized other
1.8
6.1
103
594
G04BD12
ATC
mirabegron; oral
1.6
6.1
141
891
WX704
NOMESCO Finland
Intubation
1.9
6.1
88
482
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.4
6.1
279
2066
L15
ICPC
Knee symptom/complaint
1.4
6.1
263
1924
D41.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urethra
12.6
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
211
604
3.85
64.06
3.5
2.7
—
—
—
0
0
1227
9489
2.11
38.64
6.1
4.5
—
—
—
0
0
1189
9234
2.00
34.99
6.8
4.7
2190.6
2009.9
e6/l
0.04
16
154
670
4330
1.91
34.51
4.8
3.3
91.8
81.5
e6/l
0.07
539
3394
993
7428
1.83
30.80
6.4
6.3
10.8
11.7
umol/l
2.17
946
7042
504
3076
1.91
30.02
3.4
2.6
3.8
5.6
e6/l
4.04
445
2709
726
5000
1.80
29.12
5.5
3.8
68.9
123.0
e6/l
1.20
573
3646
963
7228
1.78
28.58
9.2
6.7
1.2
1.2
mmol/l
0.03
830
6076
1306
10768
1.98
28.55
9.2
7.7
79.5
79.7
u/l
0.05
1253
10097
858
6252
1.77
27.98
5.9
4.8
35.3
35.0
g/l
1.00
805
5801
600
3957
1.81
27.41
4.7
3.2
0.2
0.5
e6/l
8.73
479
3050
584
3835
1.80
26.97
4.6
3.2
—
—
—
0
0
826
6010
1.74
26.58
9.4
10.5
1.3
1.3
inr
0.26
188
1706
889
6609
1.74
26.43
7.7
5.9
1.2
1.2
mmol/l
1.18
812
5972
875
6503
1.73
25.80
4.6
4.1
—
—
—
0
0
407
2420
1.90
25.65
3.9
2.8
1.2
1.1
e6/l
0.16
248
1426
466
2898
1.84
25.47
3.6
2.8
539.0
548.5
mosm/kgh2o
0.41
394
2469
387
2276
1.91
25.16
4.2
3.0
6.0
2.5
e6/l
0.41
229
1289
633
4437
1.69
22.13
2.9
2.5
60.6
57.2
u/l
0.84
580
4082
759
5590
1.66
21.84
2.4
2.2
—
—
—
0
0
225
1158
2.09
21.11
5.5
3.7
104.2
91.7
ng/l
1.01
202
1003
1003
7966
1.65
21.09
9.3
9.1
4.3
4.2
e9/l
0.64
864
6965
241
1281
2.03
20.69
1.3
1.4
—
—
—
0
0
122
498
2.56
19.66
2.8
3.1
0.3
0.3
g/l
0.42
59
190
864
6711
1.60
19.07
4.8
3.9
0.0
0.0
estimate
1.08
149
1234
853
6608
1.59
19.02
4.8
3.9
0.0
0.0
estimate
0.00
151
1268
855
6630
1.59
18.97
6.7
5.2
0.0
0.0
estimate
0.50
151
1271
1025
8302
1.61
18.86
5.7
4.9
6.7
6.8
mmol/l
0.65
976
7809
323
1947
1.82
18.85
8.0
5.3
1.1
1.0
mmol/l
1.80
303
1791
163
790
2.18
17.76
7.2
10.0
—
—
—
0
0
827
6440
1.56
17.46
6.3
5.8
58.4
57.8
%
0.83
773
6003
623
4550
1.59
17.39
4.1
3.3
—
—
—
0
0
231
1301
1.90
16.58
9.3
7.1
11.1
10.2
mmol/l
0.98
221
1238
819
6425
1.54
16.31
6.8
6.2
8.6
8.8
%
1.28
769
5985
1479
13368
1.93
16.30
20.6
15.8
26.6
25.3
mg/l
0.65
1249
10725
832
6554
1.54
16.23
6.5
6.0
26.6
27.1
%
0.59
774
6074
611
4500
1.56
16.15
3.0
2.5
—
—
—
0
0
245
1419
1.85
16.09
6.9
8.0
122.4
120.4
g/l
0.89
235
1370
815
6403
1.53
16.02
6.4
5.9
2.9
2.8
%
0.73
764
5938
1190
10185
1.59
15.63
4.9
4.2
13.7
13.4
mm/h
0.23
1110
9364
739
5721
1.52
15.33
2.6
2.2
78.6
78.7
nmol/l
0.03
668
5053
258
1543
1.79
15.21
6.8
7.6
96.0
95.5
%
0.90
246
1488
496
3537
1.57
14.84
4.7
4.0
92.1
88.0
%
3.12
489
3451
790
6231
1.51
14.82
6.3
5.9
0.7
0.7
%
0.67
740
5792
480
3404
1.57
14.68
2.6
2.4
—
—
—
0
0
323
2079
1.69
14.63
3.4
2.5
2.3
2.3
g/l
0.12
305
1922
653
4960
1.52
14.61
3.6
3.5
2.4
2.4
mmol/l
1.40
557
4300
278
1722
1.74
14.48
6.3
7.2
5.2
5.1
kpa
0.72
264
1649
278
1723
1.74
14.44
6.3
7.2
12.5
12.0
kpa
0.94
265
1649
871
7039
1.50
14.34
6.4
5.9
0.2
0.2
e9/l
1.27
752
6147
278
1729
1.73
14.25
6.3
7.2
0.5
1.1
mmol/l
2.56
222
1354
448
3147
1.58
14.20
4.4
3.8
—
—
—
0
0
732
5736
1.49
13.87
3.3
2.8
134.1
135.8
ug/l
0.07
677
5243
304
1955
1.68
13.74
3.6
2.5
19.7
22.4
%
3.44
254
1665
625
4752
1.50
13.68
6.1
5.8
—
—
—
0
0
238
1432
1.77
13.67
2.2
2.2
132.0
138.9
ug/g
0.11
197
1129
843
6808
1.48
13.66
6.2
5.7
0.0
0.0
e9/l
1.19
717
5855
856
6935
1.48
13.65
6.2
5.7
1.8
1.9
e9/l
0.82
738
6078
836
6781
1.47
13.00
6.2
5.7
0.6
0.6
e9/l
0.41
712
5822
599
4567
1.49
12.69
4.5
4.0
16.1
8.9
mg/mmol
2.15
401
2833
1512
13981
1.87
12.44
24.5
18.4
139.7
139.6
mmol/l
0.24
1490
13609
1514
14011
1.87
12.34
24.8
18.5
4.0
4.0
mmol/l
0.61
1488
13627
279
1818
1.64
11.86
1.3
1.3
—
—
—
0
0
583
4468
1.47
11.84
3.5
3.1
6.8
7.2
mmol/l
1.64
498
3706
332
2270
1.58
11.54
3.4
2.5
11.3
12.7
umol/l
3.18
313
2088
541
4106
1.47
11.47
5.0
4.4
—
—
—
0
0
566
4344
1.46
11.28
5.6
4.0
7.4
7.4
ph
1.16
92
844
565
4335
1.46
11.28
3.5
3.3
501.9
337.3
mg/l
0.34
378
2719
744
6028
1.42
10.96
2.4
2.0
96.2
94.3
pmol/l
0.49
375
3096
211
1310
1.70
10.74
2.6
2.3
49.9
36.8
u/l
0.58
189
1110
1481
13757
1.68
10.06
20.0
15.0
—
—
—
0
0
385
2808
1.48
9.74
4.4
3.9
168.7
331.2
ng/l
1.93
327
2284
193
1209
1.67
9.48
9.1
8.1
—
—
—
0
0
1160
10304
1.41
9.25
4.7
4.0
14.8
14.9
pmol/l
0.43
1053
9271
478
3674
1.42
9.06
3.0
2.7
5675.9
5757.6
umol/l
0.01
404
3146
239
1610
1.56
8.71
1.9
1.7
—
—
—
0
0
95
494
1.98
8.61
2.1
3.8
99.9
64.5
mg/l
0.30
78
404
170
1058
1.67
8.55
2.2
2.7
—
—
—
0
0
95
496
1.97
8.51
2.1
3.8
36.7
94.5
mg/l
1.29
77
408
480
3736
1.40
8.35
2.4
2.2
2.8
3.1
mg/l
1.16
408
3157
122
698
1.81
8.26
2.1
1.9
1.6
1.5
g/l
0.15
103
606
111
617
1.86
8.25
5.3
5.1
1.6
1.6
%
0.16
103
581
110
612
1.85
8.15
5.3
5.2
0.9
0.9
%
0.29
103
577
192
1255
1.60
7.94
2.2
2.9
66.1
66.4
g/l
0.18
172
1145
131
779
1.74
7.78
8.1
9.4
23.9
24.4
mmol/l
1.17
126
731
229
1566
1.54
7.77
2.8
2.7
5.9
9.0
umol/l
3.23
202
1372
451
3521
1.38
7.58
4.4
3.6
—
—
—
0
0
90
481
1.92
7.56
2.1
3.8
2.3
1.8
ratio
—
5
38
208
1401
1.55
7.55
1.8
1.5
—
—
—
0
0
184
1206
1.59
7.52
4.1
3.5
—
—
—
0
0
543
4373
1.36
7.50
2.4
2.1
225.5
220.1
u/l
0.03
511
4097
328
2429
1.44
7.46
1.4
1.5
2.3
2.5
g/l
1.19
193
1451
1338
12341
1.42
7.45
5.9
4.8
2.0
2.1
mu/l
0.28
1228
11150
87
463
1.93
7.40
5.7
6.4
1.2
1.3
mmol/l
0.65
78
409
69
338
2.09
7.39
5.8
7.1
11.4
11.2
mmol/l
0.16
62
306
69
338
2.09
7.39
5.8
7.1
106.4
105.3
mmol/l
0.86
62
306
41
161
2.58
7.29
1.4
1.2
—
—
nmol/l
—
0
0
230
1596
1.51
7.28
3.4
4.1
4.2
19.6
ug/l
2.29
168
1328
45
187
2.44
7.12
1.4
1.3
0.2
0.5
nmol/l
—
5
13
192
1288
1.55
7.09
7.0
6.9
1.2
1.4
mmol/l
2.65
185
1233
149
944
1.63
7.00
5.0
3.7
5.2
5.2
kpa
0.25
137
888
42
173
2.46
6.79
1.4
1.3
—
—
—
0
0
1497
14169
1.55
6.75
13.3
11.0
25.8
25.1
u/l
0.72
1456
13622
1351
12546
1.40
6.69
7.2
6.1
40.5
40.4
mmol/mol
0.22
1259
11494
240
1712
1.47
6.61
1.4
1.3
494.2
530.0
titre
0.16
62
372
282
2081
1.43
6.48
2.1
2.0
—
—
—
0
0
1192
10875
1.34
6.45
26.1
19.2
13.9
13.8
%
1.08
1175
10622
124
766
1.67
6.44
3.2
3.2
4.4
4.4
pmol/l
0.16
104
668
355
2731
1.38
6.40
1.3
1.2
0.8
1.5
u/ml
1.80
70
713
31
113
2.78
6.39
5.6
4.7
278.0
40.0
u/ml
0.57
12
32
442
3521
1.35
6.38
7.0
6.7
—
—
—
0
0
37
148
2.53
6.37
1.5
1.4
267.6
296.0
pmol/l
0.27
29
114
379
2950
1.37
6.35
5.5
4.3
1.0
1.0
kg/l
0.37
75
441
1407
13189
1.42
6.33
5.0
4.6
4.6
4.6
mmol/l
0.36
1302
12063
1396
13071
1.41
6.29
5.0
4.6
1.4
1.5
mmol/l
2.51
1284
11864
217
1534
1.48
6.25
1.3
1.3
—
—
—
0
0
144
933
1.59
6.19
5.0
3.7
7.4
7.4
ph
0.04
13
125
1533
14630
1.59
6.17
31.3
23.2
250.3
247.5
e9/l
0.88
1509
14234
548
4523
1.31
6.14
3.0
3.0
2381.7
1493.0
ng/l
1.41
466
3890
1533
14633
1.58
6.13
31.2
23.1
91.2
91.5
fl
1.94
1521
14386
1533
14634
1.58
6.11
31.1
23.1
30.2
30.4
pg
3.11
1521
14385
1533
14635
1.58
6.10
31.2
23.2
4.4
4.4
e12/l
1.36
1501
14192
1533
14638
1.58
6.06
31.3
23.2
6.8
6.8
e9/l
0.66
1503
14194
1533
14640
1.58
6.03
31.5
23.3
131.8
133.5
g/l
4.65
1521
14393
241
1752
1.44
5.99
2.8
2.5
1.8
1.8
%
0.26
207
1563
146
957
1.58
5.98
6.0
6.8
24.3
24.4
mmol/l
0.18
137
895
155
1031
1.55
5.95
2.5
2.9
10.1
10.8
g/l
1.09
141
938
75
412
1.86
5.86
1.5
1.5
236.8
278.5
ug/g
0.87
42
248
190
1329
1.48
5.77
3.0
3.0
191.5
215.8
ng/l
0.25
174
1220
381
3013
1.34
5.69
1.8
1.7
1.7
1.3
mg/l
0.96
294
2337
69
373
1.89
5.67
2.0
3.9
—
—
—
0
0
1428
13479
1.41
5.64
5.7
5.2
2.7
2.7
mmol/l
0.06
1314
12254
266
1989
1.40
5.64
1.2
1.2
—
—
—
0
0
652
5559
1.28
5.59
4.5
3.9
36.9
47.7
ng/l
0.79
476
4069
144
960
1.55
5.49
1.2
1.2
—
—
—
0
0
190
1344
1.47
5.45
5.5
3.6
1.2
2.0
mmol/l
2.18
154
1068
696
6007
1.27
5.33
11.1
10.0
0.0
0.0
e9/l
2.12
561
4932
190
1352
1.46
5.29
5.5
3.6
5.8
5.8
kpa
0.51
178
1313
127
831
1.57
5.26
1.6
1.9
1.5
1.5
g/l
0.02
116
762
183
1295
1.46
5.24
2.4
2.5
4.4
7.1
ug/l
3.53
150
1135
1348
12647
1.34
5.20
4.5
4.1
1.4
1.3
mmol/l
3.72
1229
11389
436
3560
1.30
5.14
1.7
1.6
21.3
20.6
nmol/l
0.35
373
3005
22
76
2.92
5.03
6.8
6.1
—
—
—
0
0
1264
11769
1.30
5.03
23.9
17.1
38.7
39.0
%
0.52
862
7850
69
389
1.81
5.00
3.6
3.1
24.9
25.0
mmol/l
0.05
59
342
180
1304
1.43
4.56
2.7
2.6
67.6
69.8
e9/l
0.46
135
1008
1389
13152
1.33
4.55
5.5
4.8
6.0
6.0
mmol/l
0.46
1269
11833
172
1239
1.43
4.50
1.8
1.5
—
—
—
0
0
73
435
1.71
4.41
3.4
3.3
—
—
—
0
0
34
156
2.20
4.41
1.3
1.5
—
—
—
0
0
348
2813
1.30
4.35
3.4
3.1
2.5
2.5
mmol/l
0.82
301
2479
42
211
2.02
4.33
1.3
1.4
99.3
132.6
u/ml
—
9
43
104
682
1.56
4.31
5.3
3.8
—
—
—
0
0
217
1642
1.37
4.27
1.9
1.6
—
—
—
0
0
259
2019
1.33
4.19
26.0
26.6
1.3
1.4
inr
0.37
41
270
46
242
1.93
4.18
1.3
1.4
—
—
—
0
0
143
1013
1.45
4.11
4.5
4.7
—
—
—
0
0
32
148
2.18
4.09
3.1
3.3
—
—
—
0
0
61
354
1.75
4.07
1.2
1.2
58.0
89.3
titre
—
5
28
528
4527
1.24
4.01
5.8
5.4
2.8
3.2
ug/l
0.52
475
4001
359
2944
1.28
3.99
1.9
1.7
1072.1
1175.6
nmol/l
1.44
257
2191
114
781
1.49
3.89
1.3
1.4
—
—
—
0
0
89
579
1.57
3.85
5.6
4.1
24.2
24.9
mmol/l
1.62
83
535
101
678
1.52
3.80
6.1
3.9
23.4
24.1
mmol/l
1.45
94
617
74
462
1.63
3.79
2.2
2.6
38.3
37.3
g/l
0.81
67
403
93
615
1.54
3.75
2.9
1.9
—
—
—
0
0
152
1112
1.40
3.68
4.8
2.9
4.9
4.5
kpa
1.55
142
1076
192
1463
1.35
3.62
6.7
4.4
—
—
—
0
0
86
564
1.55
3.61
3.0
3.2
1050.2
7222.4
u/ml
0.68
80
485
56
332
1.71
3.51
1.3
1.2
1.2
3.0
u/ml
—
8
34
121
857
1.44
3.51
6.8
7.5
24.4
24.9
mmol/l
0.63
121
851
111
776
1.46
3.45
2.6
2.4
—
—
—
0
0
167
1265
1.36
3.29
2.2
2.2
411.2
372.1
nmol/l
1.56
150
1147
289
2362
1.27
3.27
3.1
3.2
0.8
0.8
mmol/l
0.03
267
2211
1049
9753
1.20
3.25
4.4
4.1
—
—
—
0
0
124
898
1.41
3.20
4.6
3.1
124.1
127.1
g/l
0.75
119
874
23
104
2.23
3.16
1.1
1.1
—
—
—
0
0
57
351
1.65
3.14
1.4
1.7
25146.4
13063.8
e6/l
0.44
40
262
53
323
1.66
3.04
2.2
2.2
134.0
128.4
g/l
0.57
29
242
60
378
1.61
3.03
1.7
1.5
0.2
0.2
g/l
0.01
54
357
32
169
1.91
2.95
1.3
1.5
—
—
—
0
0
263
2152
1.26
2.95
1.3
1.2
12.8
13.5
u/ml
0.04
95
802
8
17
4.72
2.92
8.9
10.8
5.4
5.8
mmol/l
—
8
17
28
142
1.99
2.90
1.6
1.5
—
—
—
0
0
50
305
1.66
2.88
1.4
1.8
4.3
5.2
iu/l
0.23
20
97
73
488
1.52
2.87
1.2
1.3
0.3
0.9
u/ml
—
5
41
203
1614
1.29
2.87
1.3
1.4
—
—
—
0
0
18
77
2.35
2.82
1.4
1.3
—
—
—
0
0
104
749
1.41
2.80
4.7
3.7
—
—
—
0
0
36
202
1.80
2.78
1.6
2.0
10034.7
2886.0
u/l
—
10
77
31
166
1.88
2.76
1.3
1.1
—
—
—
0
0
178
1400
1.30
2.73
2.1
2.2
0.2
0.2
g/l
0.69
162
1308
37
213
1.75
2.64
1.2
1.3
—
—
—
0
0
19
86
2.22
2.64
2.4
3.6
—
—
—
0
0
34
195
1.76
2.47
1.1
1.0
—
—
—
0
0
34
196
1.75
2.43
1.9
1.6
0.8
0.9
g/l
0.19
26
143
68
466
1.48
2.42
1.6
1.6
—
—
—
0
0
115
866
1.35
2.41
1.3
1.3
—
—
—
0
0
25
131
1.92
2.41
1.2
1.4
31.9
29.6
u/l
0.09
18
107
18
84
2.15
2.35
1.8
1.9
11.6
13.3
%
—
7
34
22
112
1.98
2.30
2.0
2.0
2.1
1.1
e9/l
0.62
13
68
49
317
1.56
2.28
4.2
3.0
—
—
—
0
0
6
13
4.63
2.27
1.0
1.2
—
—
—
0
0
33
193
1.72
2.27
1.1
1.1
—
—
—
0
0
37
224
1.67
2.25
1.4
1.4
—
—
—
0
0
418
3681
1.18
2.23
5.4
4.2
0.0
0.0
estimate
0.88
147
1225
37
225
1.66
2.21
1.4
1.4
—
—
—
0
0
264
2234
1.22
2.18
1.3
1.3
32.4
34.4
iu/ml
0.10
79
725
44
281
1.58
2.18
3.1
2.8
—
—
—
0
0
8
24
3.34
2.18
1.0
1.5
—
—
—
0
0
38
234
1.64
2.17
1.4
1.5
—
—
—
0
0
6
14
4.30
2.15
1.0
1.0
—
—
—
0
0
19
95
2.01
2.10
1.2
1.2
1.7
2.0
mmol/l
1.46
19
89
95
711
1.36
2.10
4.9
3.2
25.4
25.3
mmol/l
0.08
90
688
121
940
1.31
2.08
4.1
3.0
—
—
—
0
0
36
223
1.63
2.03
1.4
1.4
—
—
—
0
0
116
902
1.31
1.99
2.8
3.0
4.7
4.1
e9/l
0.34
83
686
85
631
1.37
1.99
1.5
1.5
—
—
—
0
0
10
39
2.57
1.92
1.7
1.6
—
—
—
0
0
28
165
1.71
1.91
1.4
1.4
—
—
—
0
0
133
1060
1.28
1.91
4.5
4.2
0.1
0.4
%
0.52
30
284
48
325
1.49
1.87
1.1
1.2
—
—
—
0
0
34
213
1.61
1.86
1.6
1.4
32.3
32.3
g/l
0.01
28
192
35
221
1.60
1.85
1.0
1.2
268.6
276.1
u/ml
0.07
24
127
11
46
2.40
1.85
1.5
1.5
—
—
—
0
0
361
3189
1.17
1.84
1.7
1.7
51178880.7
30285924.2
pmol/l
0.24
297
2592
102
789
1.31
1.84
2.1
2.2
11.1
12.0
nmol/l
0.45
83
677
49
335
1.48
1.83
3.9
3.0
8.2
7.9
kpa
0.61
44
308
32
199
1.62
1.80
1.3
1.2
—
—
—
0
0
7
23
3.05
1.80
1.0
1.1
—
—
—
0
0
35
223
1.58
1.79
1.4
1.4
—
—
—
0
0
15
74
2.04
1.75
2.1
2.2
0.2
0.2
e9/l
0.17
15
67
20
110
1.83
1.73
1.4
1.2
—
—
—
0
0
147
1202
1.24
1.72
4.2
4.0
0.8
1.0
%
0.25
40
366
27
164
1.66
1.68
1.3
1.4
—
—
—
0
0
22
126
1.76
1.68
4.1
3.3
91.5
32.6
mg/l
1.04
17
95
19
104
1.84
1.67
1.3
1.1
—
—
—
0
0
35
228
1.55
1.65
1.5
1.4
—
—
—
0
0
91
705
1.31
1.65
1.3
1.2
—
—
—
0
0
24
142
1.70
1.64
1.7
1.8
—
—
—
0
0
18
99
1.83
1.57
1.4
1.5
—
—
—
0
0
11
50
2.21
1.57
3.7
2.6
—
—
—
0
0
27
168
1.62
1.55
1.6
2.2
—
—
—
0
0
28
176
1.60
1.55
1.1
1.3
106181.9
117151.8
e6/l
0.06
16
103
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
55
401
1.38
1.50
4.3
4.8
—
—
—
0
0
137
1131
1.23
1.49
4.2
4.1
0.1
0.1
%
0.05
35
331
15
79
1.91
1.49
1.8
2.1
1083.8
735.1
e6/l
—
8
36
68
514
1.34
1.48
2.6
2.2
145.1
473.2
ug/l
2.50
63
483
44
310
1.43
1.46
5.3
3.3
8.1
7.7
mmol/l
0.22
44
301
20
118
1.70
1.41
1.2
1.3
0.3
0.4
g/l
0.23
13
78
20
118
1.70
1.41
1.2
1.3
2.5
2.8
g/l
0.29
14
79
20
118
1.70
1.41
1.2
1.3
6.6
7.1
g/l
0.23
14
79
122
1003
1.23
1.40
1.5
1.4
—
—
—
0
0
39
271
1.45
1.40
1.3
1.6
—
—
—
0
0
46
330
1.40
1.39
3.8
2.1
—
—
—
0
0
45
322
1.41
1.38
3.9
4.1
—
—
—
0
0
470
4312
1.12
1.37
5.2
4.1
—
—
—
0
0
31
208
1.50
1.33
1.5
1.4
—
—
—
0
0
26
168
1.56
1.31
1.3
1.3
—
—
—
0
0
89
712
1.26
1.31
3.1
3.6
38.4
62.7
u/ml
0.98
84
685
49
360
1.37
1.31
1.2
1.7
—
—
—
0
0
20
121
1.66
1.30
1.2
1.3
—
—
—
0
0
5
18
2.78
1.28
2.4
1.3
200.2
88.9
ng/l
—
5
18
80
634
1.27
1.27
1.9
2.0
3.4
2.5
ug/l
0.20
64
560
19
115
1.66
1.24
1.2
1.2
—
—
—
0
0
29
195
1.50
1.24
1.3
1.3
5359.7
1758.7
e6/l
0.89
20
139
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
13
70
1.86
1.24
1.1
1.0
—
—
—
0
0
26
171
1.53
1.23
1.3
1.2
—
—
—
0
0
39
279
1.41
1.23
1.3
1.3
318.6
238.8
miu/ml
—
7
120
8
37
2.17
1.21
1.3
1.2
—
—
—
0
0
19
116
1.64
1.21
1.1
1.2
—
—
—
0
0
16
93
1.73
1.21
1.8
1.5
—
—
—
0
0
287
2578
1.14
1.18
3.3
3.3
0.9
0.8
ug/l
0.67
207
1827
14
79
1.78
1.17
1.5
2.8
—
—
—
0
0
27
182
1.49
1.16
1.5
1.6
46.6
62.6
%
1.02
18
116
400
3671
1.12
1.15
1.7
1.7
1.4
1.3
mmol/l
0.56
352
3052
78
626
1.26
1.14
1.3
1.2
—
—
—
0
0
12
65
1.85
1.13
1.1
1.0
—
—
—
0
0
128
1086
1.19
1.11
4.3
3.9
0.8
0.7
%
0.18
26
262
10
51
1.97
1.11
1.1
1.3
4.4
3.5
mmol/l
—
10
45
47
354
1.34
1.11
2.0
2.1
13.3
11.8
mg/l
0.41
41
325
5
21
2.38
1.09
1.6
1.7
—
—
—
0
0
19
120
1.59
1.08
2.3
2.5
—
—
—
0
0
14
82
1.71
1.05
1.0
1.1
—
—
—
0
0
26
179
1.46
1.03
2.0
8.3
6.7
7.6
mmol/l
0.66
19
151
7
34
2.06
1.03
1.4
1.6
—
—
—
0
0
21
141
1.49
0.95
1.3
1.3
306085.3
142013.4
e6/l
0.24
11
97
374
3460
1.10
0.93
1.4
1.4
—
—
—
0
0
20
134
1.50
0.91
1.3
1.2
—
—
—
0
0
15
94
1.60
0.90
1.1
1.8
—
—
—
0
0
33
245
1.35
0.89
4.1
2.6
—
—
—
0
0
97
823
1.19
0.88
1.3
1.3
—
—
—
0
0
13
79
1.65
0.88
1.6
1.6
—
11.7
—
0
5
8
44
1.82
0.86
1.0
1.3
16.0
24.0
%
—
8
32
17
112
1.52
0.85
1.4
1.2
16.4
13.2
u/l
0.26
17
103
6
31
1.94
0.84
3.5
6.7
—
—
—
0
0
18
121
1.49
0.82
1.4
1.9
—
—
—
0
0
8
46
1.74
0.82
1.4
1.1
953.6
1714.5
miu/ml
—
8
46
13
81
1.61
0.81
2.6
2.6
—
—
—
0
0
36
276
1.31
0.80
1.3
1.5
1.0
0.8
nmol/l
0.53
31
224
0
24
0.00
0.79
0.0
1.1
—
24.7
—
0
17
102
880
1.17
0.78
2.6
2.5
25.5
18.6
au/ml
—
5
38
48
384
1.26
0.78
1.1
1.1
—
—
—
0
0
19
131
1.45
0.78
1.1
1.3
—
—
—
0
0
21
148
1.42
0.77
1.9
3.5
64.2
55.2
%
0.96
13
100
6
34
1.77
0.76
1.3
2.1
—
—
—
0
0
22
158
1.40
0.74
1.2
1.3
291.6
276.2
mosm/kgh2o
0.94
16
113
9
55
1.64
0.73
1.0
1.2
—
—
—
0
0
5
25
2.00
0.72
5.2
7.0
—
—
—
0
0
18
126
1.43
0.70
2.3
1.9
1.7
1.9
u/field
—
7
49
9
142
0.63
0.69
1.3
1.1
—
—
—
0
0
13
85
1.53
0.69
1.5
1.4
0.8
1.1
promille
—
8
65
5
27
1.85
0.68
1.0
1.0
0.1
0.3
u/ml
—
5
12
12
77
1.56
0.68
1.8
1.6
—
—
—
0
0
36
284
1.27
0.68
1.6
1.5
—
—
—
0
0
66
557
1.19
0.68
1.1
1.1
—
136.0
—
0
11
150
1347
1.12
0.68
1.6
1.6
—
—
—
0
0
45
366
1.24
0.66
2.8
2.4
231.0
81.8
ug/min
0.63
30
221
30
234
1.29
0.63
1.5
1.3
12.4
10.9
u/l
0.17
24
185
17
121
1.41
0.62
1.1
1.3
—
30.8
—
0
8
305
2854
1.08
0.62
5.0
4.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
46.1
—
0
20
8
51
1.57
0.60
1.9
1.3
4.1
2.9
%
—
8
43
12
80
1.50
0.59
1.1
1.7
—
—
—
0
0
6
35
1.72
0.57
2.8
4.2
—
—
—
0
0
26
202
1.29
0.57
2.2
2.3
9.9
24.3
u/ml
0.33
26
195
16
115
1.39
0.56
2.1
2.9
10.8
11.1
%
0.10
16
115
86
757
1.14
0.55
1.4
1.2
160.6
164.8
u/ml
0.03
79
688
42
348
1.21
0.55
4.1
4.8
8.6
8.3
kpa
0.60
42
343
135
1224
1.11
0.55
4.9
3.6
1.2
1.2
mmol/l
0.26
128
1054
33
268
1.24
0.52
1.2
1.3
—
—
—
0
0
47
400
1.18
0.48
1.1
1.1
—
—
—
0
0
7
110
0.63
0.48
1.0
1.4
—
—
—
0
0
13
93
1.40
0.48
1.6
3.3
7.4
7.4
ph
—
6
30
131
1197
1.10
0.47
1.6
1.5
—
—
—
0
0
17
128
1.33
0.47
1.1
1.4
—
—
—
0
0
10
68
1.47
0.47
1.1
1.2
130.6
414.8
u/l
—
10
63
41
346
1.19
0.46
3.9
4.8
2.8
2.8
mmol/l
0.01
32
245
41
347
1.19
0.45
3.9
4.8
5.1
5.1
kpa
0.21
41
342
7
50
1.40
0.45
2.0
2.6
—
—
—
0
0
12
86
1.40
0.44
1.7
1.3
—
—
—
0
0
8
57
1.40
0.42
4.6
3.5
—
—
—
0
0
23
185
1.25
0.41
1.2
1.2
3.8
5.3
u/ml
0.34
14
83
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
820.9
—
0
6
23
186
1.24
0.40
3.6
2.7
—
—
—
0
0
7
103
0.68
0.39
2.1
2.3
13.3
13.2
%
—
7
103
11
148
0.74
0.38
1.0
1.1
—
—
—
0
0
11
80
1.38
0.38
1.1
1.6
—
—
—
0
0
9
66
1.37
0.38
4.2
3.3
—
—
—
0
0
9
68
1.32
0.37
1.1
1.2
—
—
—
0
0
11
147
0.75
0.37
1.0
1.1
—
—
—
0
0
9
69
1.31
0.37
1.6
1.4
—
4.4
%
—
0
14
73
806
0.90
0.36
1.3
1.4
—
—
—
0
0
22
180
1.22
0.36
1.0
1.1
—
15.9
—
0
9
6
42
1.43
0.35
1.0
2.0
3.4
1.3
ug/l
—
6
37
6
42
1.43
0.35
1.5
1.3
—
—
—
0
0
6
43
1.40
0.35
1.8
2.1
—
—
—
0
0
6
45
1.33
0.33
2.0
1.6
—
—
—
0
0
12
155
0.77
0.33
1.1
1.2
—
—
—
0
0
6
46
1.30
0.33
2.0
2.2
—
—
—
0
0
37
322
1.15
0.32
3.0
2.6
15.9
15.9
%
0.00
23
162
89
820
1.09
0.31
1.3
1.2
66.2
132.4
iu/ml
2.03
29
320
39
442
0.88
0.31
8.5
11.4
—
—
—
0
0
16
130
1.23
0.28
1.3
1.5
0.2
0.3
nmol/l
1.97
11
102
8
62
1.29
0.28
2.0
1.3
66.4
62.9
%
—
8
47
12
94
1.28
0.28
1.1
1.1
—
—
—
0
0
416
4278
0.96
0.27
3.2
3.0
—
—
—
0
0
19
160
1.19
0.25
2.2
2.7
—
—
—
0
0
9
75
1.20
0.25
12.2
15.2
—
—
—
0
0
5
40
1.25
0.22
2.4
1.5
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
20
172
1.16
0.22
2.6
4.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
6.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
1.9
—
0
10
0
11
0.00
0.21
0.0
1.6
—
1.4
—
0
6
37
334
1.11
0.21
1.1
1.2
—
—
—
0
0
13
156
0.83
0.21
1.2
1.1
2.2
2.8
u/ml
—
5
63
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
15
126
1.19
0.21
2.5
2.2
—
—
—
0
0
19
164
1.16
0.20
1.2
1.2
—
—
—
0
0
18
157
1.15
0.17
1.1
1.4
—
—
—
0
0
9
78
1.15
0.15
1.0
1.0
—
—
—
0
0
27
245
1.10
0.15
2.0
3.8
1.7
1.6
%
0.06
20
195
16
182
0.88
0.15
1.2
1.3
—
—
—
0
0
24
217
1.11
0.14
1.9
2.6
—
—
—
0
0
32
295
1.09
0.14
2.6
3.7
58.4
59.1
%
0.12
32
295
47
441
1.07
0.13
1.0
1.1
—
—
—
0
0
62
588
1.06
0.13
4.6
4.4
—
—
—
0
0
11
94
1.17
0.13
1.3
2.5
—
—
—
0
0
17
152
1.12
0.12
2.5
2.0
—
—
—
0
0
11
95
1.16
0.11
2.4
2.2
—
—
—
0
0
10
86
1.16
0.11
1.6
1.6
0.8
1.0
g/l
—
10
86
11
123
0.89
0.08
2.7
2.4
831.0
630.1
ml
—
6
78
15
137
1.10
0.07
1.5
1.4
31.2
31.3
%
—
9
85
55
569
0.97
0.07
1.9
1.4
—
—
—
0
0
30
285
1.05
0.06
2.5
3.4
4.1
4.3
e9/l
0.41
30
285
53
512
1.04
0.06
1.8
1.8
—
—
—
0
0
9
102
0.88
0.06
1.6
1.1
33.3
34.8
mmol/l
—
9
92
33
344
0.96
0.05
1.3
1.3
—
—
—
0
0
11
101
1.09
0.04
1.2
1.2
0.4
4.0
nmol/l
—
5
21
10
92
1.09
0.03
1.6
1.5
—
—
—
0
0
36
370
0.97
0.03
1.2
1.1
—
—
—
0
0
16
168
0.95
0.02
1.0
1.2
—
—
—
0
0
36
351
1.03
0.02
2.9
3.3
0.8
0.8
nmol/l
0.01
31
276
33
322
1.02
0.01
3.9
3.6
37.5
26.3
mg/l
0.71
21
206
20
206
0.97
0.00
2.6
2.7
—
—
—
0
0
17
171
0.99
0.00
1.4
1.5
—
—
—
0
0
17
171
0.99
0.00
1.4
1.5
—
—
—
0
0
17
171
0.99
0.00
1.4
1.5
—
—
—
0
0
17
171
0.99
0.00
1.4
1.5
—
—
—
0
0
19
191
0.99
0.00
1.3
1.7
—
—
—
0
0
32
324
0.99
0.00
1.6
2.9
27.7
34.8
umol/l
1.02
21
267
34
337
1.01
0.00
1.2
1.3
462.3
516.8
mg/l
0.56
34
317
14
136
1.03
0.00
1.1
1.1
—
—
—
0
0
30
305
0.98
0.00
1.1
1.2
—
—
—
0
0
119
1188
1.00
0.00
5.5
4.0
—
—
—
0
0
23
228
1.01
0.00
2.6
1.4
—
—
—
0
0
17
172
0.99
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.5
1.3
—
—
—
0
0
5
53
0.94
0.00
1.0
1.1
83.2
229.4
iu/ml
—
5
53
5
52
0.96
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.1
—
0
6
9
92
0.98
0.00
1.4
1.7
—
72.1
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
0.00
1.7
1.4
—
—
—
0
0
9
99
0.91
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
33.9
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
0.00
1.3
1.2
124.3
137.3
nmol/l
—
7
74
0
6
0.00
0.00
0.0
1.0
—
16.2
—
0
6
9
90
1.00
0.00
1.7
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_URINARY and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_URINARY 1.337 [1.19, 1.5] < 0.001
Birth year 0.996 [0.99, 1.0] 0.32

During the follow-up period (1.1.1998 — 31.12.2019), 899 out of 4105 females with CD2_BENIGN_URINARY died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_URINARY 1.422 [1.26, 1.61] < 0.001
Birth year 0.991 [0.98, 1.0] 0.059

During the follow-up period (1.1.1998 — 31.12.2019), 1092 out of 3120 males with CD2_BENIGN_URINARY died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_URINARY.

N-year risk Females Males
1 0.09% 0.272%
5 0.73% 1.823%
10 1.935% 4.401%
15 3.666% 8.57%
20 6.835% 14.215%

Relationships between endpoints

Index endpoint: CD2_BENIGN_URINARY – Benign neoplasm of urinary organs

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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