No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1185 |
4. Check minimum number of eventsNone |
1185 |
5. Include endpointsNone |
1185 |
6. Filter based on genotype QC (FinnGen only) |
1185 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D30
- Name in latin
- Neoplasma benignum renis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Kidney
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Kidney
- Benign neoplasm of urinary organs
- Benign neoplasm of urinary organs
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6609 | 3971 | 2585 |
| Only index persons | 5892 | 3682 | 2210 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.07 |
| Only index persons | 0.12 | 0.14 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 63.31 | 61.47 | 66.18 |
| Only index persons | 62.69 | 60.74 | 65.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1185 | 718 | 467 |
| Unadjusted period prevalence (%) | 0.23 | 0.24 | 0.21 |
| Median age at first event (years) | 61.86 | 58.81 | 66.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1035
- Matched controls
- 10346
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
66.0
323.0
430
110
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
+∞
323.0
976
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
24.3
135.8
197
99
KAD00
NOMESCO Finland
Partial nephrectomy
91.2
89.8
99
12
KA1AE
NOMESCO Finland
Kidney ultrasound examination
14.5
64.6
112
86
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
40.6
57.4
72
19
KAC10
NOMESCO Finland
Total nephrectomy with capsule
21.2
50.4
75
38
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
15.0
46.1
78
56
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
38.6
43.6
55
15
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
39.8
38
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
24.7
32.0
45
19
PC5DT
NOMESCO Finland
Embolisation of tumor of kidney
+∞
31.4
30
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
29.3
204
810
N28.1
ICD-10 Finland
Cyst of kidney
10.5
29.0
57
57
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.2
27.6
89
184
UKC02
NOMESCO Finland
Cystoscopy
2.6
27.6
243
1105
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
13.6
27.1
47
36
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
25.9
420
2548
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
25.7
338
1869
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.0
25.4
106
285
N02AX02
ATC
tramadol; systemic, rectal
2.0
25.0
508
3363
N02BE01
ATC
paracetamol; systemic, rectal
2.5
22.6
920
7880
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.8
22.0
97
273
D30.3
ICD-10 Finland
Benign neoplasm: Bladder
63.9
21.9
25
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
21.3
119
403
22300
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
20.9
20
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
20.8
153
620
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
19.8
147
598
PC5ET
NOMESCO Finland
Extensive embolisation of tumor of kidney
+∞
18.8
18
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
12.2
17.4
31
26
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
16.5
650
5074
KAC00
NOMESCO Finland
Nephrectomy
20.4
16.5
24
12
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
7.5
16.3
38
52
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
9.4
16.2
33
36
U14
ICPC
Kidney symptom/complaint
6.9
16.1
40
60
ZXA00
NOMESCO Finland
Right side
1.9
15.9
318
2000
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
15.2
91
321
R31
ICD-10 Finland
Unspecified haematuria
2.4
14.8
132
593
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
14.8
235
1359
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
14.5
183
963
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.8
14.5
62
171
8260/3-C64.9
ICD-O-3
Papillary adenocarcinoma, NOS, of kidney, NOS
19.4
14.3
21
11
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.6
13.7
102
413
R4110
NOMESCO Finland
Physiotherapy
1.8
13.7
287
1818
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.3
13.3
40
78
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.0
469
3474
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
12.8
228
1363
J01DB01
ATC
cefalexin; oral
1.8
12.8
822
7104
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
12.5
12.6
22
18
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
131.5
12.5
13
*
A02BC05
ATC
esomeprazole; systemic
1.6
12.1
430
3150
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
11.2
12.1
22
20
A02BC02
ATC
pantoprazole; systemic
1.6
12.0
674
5550
ZXA05
NOMESCO Finland
Left side
1.7
11.8
288
1899
J01MA02
ATC
ciprofloxacin; systemic
1.6
11.7
406
2951
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
7.0
11.7
28
41
XKD00
NOMESCO Finland
Uroflowmetry
1.9
11.5
184
1054
JN4CD
NOMESCO Finland
Very extensive body CT
3.2
11.5
61
201
JN4AD
NOMESCO Finland
Body CT examination
2.5
11.4
94
402
B01AB05
ATC
enoxaparin; parenteral
1.6
11.4
343
2398
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.2
207
1247
JN4BD
NOMESCO Finland
Extensive body CT
2.1
11.1
137
711
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
11.1
172
975
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.8
10.8
35
75
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.1
10.8
132
681
PC5SC
NOMESCO Finland
Selective angiography of kidney artery with X-ray
60.6
10.6
12
*
B01AB10
ATC
tinzaparin; parenteral
2.4
10.5
91
400
KH1AD
NOMESCO Finland
CT of urinary organs
3.8
10.5
43
116
7125
FHL
Nephrectomy (extrrafascial)
32.9
10.3
13
*
G04CA02
ATC
tamsulosin; oral
1.7
10.0
231
1487
N20.1
ICD-10 Finland
Calculus of ureter
3.3
9.9
48
149
S18
ICPC
Laceration/cut
1.5
9.9
438
3340
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
9.9
206
1285
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
9.8
307
2148
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
5.6
9.7
27
49
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
55.5
9.7
11
*
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
7.6
9.4
21
28
Q85.1
ICD-10 Finland
Tuberous sclerosis
+∞
9.4
9
*
C08CA01
ATC
amlodipine; oral
1.5
9.2
378
2817
A02BC03
ATC
lansoprazole; oral
1.6
9.1
310
2208
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
8.8
383
2887
D30.9
ICD-10 Finland
Benign neoplasm: Urinary organ, unspecified
50.4
8.7
10
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
8.7
144
831
R50.9
ICD-10 Finland
Fever, unspecified
1.9
8.5
136
776
D01
ICPC
Abdominal pain/cramps general
2.1
8.5
99
501
KB1CG
NOMESCO Finland
Extensive MRI examination of urinary tract with high intensity magnet
90.7
8.4
9
*
U79
ICPC
Neoplasm urinary tract unspecified
90.7
8.4
9
*
KA4AT
NOMESCO Finland
Cytology of kidney with ultrasound guidance
+∞
8.3
8
*
WX110
NOMESCO Finland
Local anesthesy
1.5
8.2
648
5503
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.0
378
2882
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.3
8.0
70
312
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
8.0
91
455
N20.0
ICD-10 Finland
Calculus of kidney
4.0
7.9
30
77
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
7.7
229
1567
KA3LT
NOMESCO Finland
Njurlesion coagulation
18.5
7.6
11
6
A02BC01
ATC
omeprazole; systemic
1.5
7.6
287
2082
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
7.6
140
840
J01AA02
ATC
doxycycline; systemic
1.5
7.4
769
6825
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.4
436
3461
U07
ICPC
Urine symptom/complaint other
2.3
7.4
69
317
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
6.5
7.4
18
28
UJF32
NOMESCO Finland
Coloscopy
1.5
7.3
271
1953
WX402
NOMESCO Finland
General anaesthesia
1.7
7.1
150
936
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
7.1
115
659
D02
ICPC
Abdominal pain epigastric
2.3
7.1
62
279
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.0
342
2611
KCD02
NOMESCO Finland
Transurethral resection of bladder
3.4
7.0
32
97
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
7.0
152
956
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
6.9
207
1415
J01EA01
ATC
trimethoprim; systemic
1.5
6.8
255
1840
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
7.2
6.7
15
21
C64.80
ICD-10 Finland
Wilms tumour
22.7
6.7
9
*
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
22.7
6.7
9
*
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
4.5
6.7
22
50
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
6.6
309
2334
R51.80
ICD-10 Finland
Headache
1.7
6.5
131
807
L15
ICPC
Knee symptom/complaint
1.6
6.5
205
1419
D30.1
ICD-10 Finland
Benign neoplasm: Renal pelvis
70.2
6.4
7
*
N20.9
ICD-10 Finland
Urinary calculus, unspecified
3.4
6.4
29
88
PC5NT
NOMESCO Finland
Endovascular embolisation for kidney bleeding with radiological guidance
+∞
6.3
6
*
WX704
NOMESCO Finland
Intubation
2.1
6.3
70
349
C07AB07
ATC
bisoprolol; oral
1.4
6.2
476
3929
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.2
206
1442
R03AC02
ATC
salbutamol; inhalant
1.4
6.2
492
4090
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
6.1
37
137
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
6.0
65
322
M03BX02
ATC
tizanidine; oral
1.4
6.0
558
4747
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
986
7843
2.53
31.96
8.9
7.7
79.9
78.9
u/l
0.25
947
7341
744
5403
2.01
28.70
6.3
6.2
10.7
11.4
umol/l
1.18
708
5118
721
5238
1.96
27.06
9.2
6.8
1.2
1.2
mmol/l
0.22
634
4419
647
4537
1.94
26.94
6.0
4.7
35.5
35.2
g/l
0.80
611
4213
856
6670
2.02
25.33
6.2
4.8
1675.8
2433.9
e6/l
—
9
114
664
4809
1.87
23.87
7.9
5.9
1.2
1.2
mmol/l
0.78
613
4342
484
3239
1.83
21.85
2.8
2.4
61.7
56.8
u/l
1.18
445
2971
440
2863
1.85
21.72
4.1
3.2
0.2
0.5
e6/l
5.65
353
2193
647
4760
1.79
20.99
4.5
4.1
—
—
—
0
0
302
1766
1.95
20.51
3.2
2.8
1.0
1.2
e6/l
0.18
183
1030
179
867
2.25
20.06
5.4
3.6
103.5
86.7
ng/l
1.30
159
752
286
1654
1.96
20.01
3.5
3.0
1.7
2.7
e6/l
1.74
168
925
251
1397
2.01
19.55
8.1
5.3
1.1
1.0
mmol/l
0.92
234
1273
353
2216
1.84
19.07
3.2
2.6
3.8
5.7
e6/l
4.50
311
1961
744
5797
1.76
18.90
9.3
9.2
4.3
4.1
e9/l
1.63
646
5091
179
912
2.13
17.57
9.5
7.2
10.9
9.9
mmol/l
1.11
172
868
194
1020
2.08
17.53
6.7
7.8
122.0
120.1
g/l
0.69
187
990
753
5990
1.70
16.71
5.7
4.8
6.7
6.8
mmol/l
0.54
722
5639
1087
9718
2.43
16.42
20.0
15.5
27.4
24.5
mg/l
1.63
914
7801
217
1224
1.95
16.00
6.3
7.1
5.2
5.1
kpa
0.28
206
1179
217
1225
1.94
15.95
6.2
7.1
12.4
12.1
kpa
0.43
207
1180
217
1230
1.94
15.75
6.3
7.1
0.5
1.3
mmol/l
2.50
174
976
565
4223
1.65
15.48
2.6
2.2
78.7
78.9
nmol/l
0.04
513
3733
443
3125
1.67
15.14
3.5
3.2
30.2
32.3
u/l
0.87
420
2976
460
3281
1.66
15.04
4.4
3.9
18.0
8.4
mg/mmol
2.37
309
2031
884
7450
1.73
14.82
4.6
4.3
13.2
13.1
mm/h
0.02
824
6837
449
3207
1.64
14.45
3.4
3.1
6.8
7.2
mmol/l
1.36
388
2658
1113
10177
2.54
13.84
24.3
18.0
139.7
139.7
mmol/l
0.16
1100
9904
1114
10203
2.53
13.56
24.6
18.1
4.0
4.0
mmol/l
0.32
1097
9919
490
3638
1.59
13.11
3.7
3.5
2.4
2.4
mmol/l
1.22
419
3160
618
4860
1.57
12.76
6.6
5.3
0.0
0.0
estimate
0.50
108
936
358
2481
1.63
12.65
2.6
2.4
—
—
—
0
0
615
4840
1.56
12.60
4.6
3.9
0.0
0.0
estimate
0.00
107
936
165
921
1.92
12.37
2.6
2.3
55.1
37.7
u/l
0.61
149
781
622
4920
1.56
12.37
4.7
4.0
0.0
0.0
estimate
0.80
104
918
296
1985
1.65
11.79
4.4
3.9
152.7
326.6
ng/l
1.70
248
1599
92
439
2.19
10.56
5.0
5.2
1.6
1.6
%
0.27
87
418
232
1499
1.68
10.54
3.6
2.4
2.3
2.3
g/l
0.15
219
1389
734
6158
1.50
10.15
3.5
3.1
59.9
50.6
u/l
1.15
692
5683
219
1409
1.68
10.08
3.8
2.5
20.1
22.5
%
1.93
179
1195
182
1119
1.74
9.88
3.0
2.7
6.2
8.5
umol/l
1.71
163
976
173
1055
1.75
9.65
2.3
2.2
120.1
132.9
ug/g
0.24
140
822
530
4205
1.47
9.44
3.4
2.7
130.9
131.9
ug/l
0.03
495
3834
899
7941
1.55
9.18
25.9
19.0
13.9
13.8
%
0.74
887
7768
544
4366
1.45
8.98
2.3
2.0
97.0
95.4
pmol/l
0.32
278
2203
40
139
2.94
8.92
1.5
1.3
0.2
0.6
nmol/l
—
5
10
40
140
2.92
8.81
1.5
1.3
0.7
0.6
nmol/l
0.65
40
131
152
919
1.75
8.71
3.0
3.0
152.2
214.8
ng/l
1.26
140
842
239
1634
1.58
8.50
3.7
2.4
11.2
12.7
umol/l
3.35
226
1505
1014
9270
1.65
8.32
19.6
14.4
71.9
77.3
ml/min/173m2
11.68
883
7682
1103
10345
1.95
8.02
13.2
11.0
26.1
24.9
u/l
1.28
1077
9935
862
7632
1.47
7.92
4.7
4.1
14.8
14.9
pmol/l
0.30
790
6882
639
5363
1.41
7.84
3.0
2.7
—
—
—
0
0
1047
9685
1.69
7.78
5.1
4.6
4.6
4.6
mmol/l
0.51
976
8878
408
3168
1.44
7.72
2.5
2.1
155.6
234.3
u/l
1.68
385
2980
1040
9611
1.67
7.66
5.0
4.6
1.4
1.5
mmol/l
2.70
962
8740
28
87
3.27
7.55
5.5
4.6
259.8
47.7
u/ml
—
10
24
147
928
1.67
7.17
7.0
6.5
1.1
1.4
mmol/l
3.36
140
890
1125
10675
2.06
7.09
31.0
22.9
253.9
249.0
e9/l
1.58
1109
10385
999
9183
1.56
7.07
7.2
6.1
40.4
40.2
mmol/mol
0.30
933
8424
1125
10679
2.05
7.02
30.9
22.9
4.4
4.4
e12/l
0.48
1104
10353
173
1145
1.60
6.99
3.5
4.0
4.1
22.5
ug/l
1.83
124
944
1125
10681
2.05
6.99
30.9
23.0
6.9
6.7
e9/l
1.89
1105
10350
1059
9877
1.68
6.97
5.8
5.2
2.7
2.7
mmol/l
0.27
982
8986
1125
10683
2.04
6.95
31.1
23.1
131.8
133.5
g/l
3.46
1118
10500
31
108
2.92
6.93
1.5
1.4
278.2
294.0
pmol/l
0.12
23
86
346
2654
1.43
6.85
3.0
2.7
7635.6
6216.2
umol/l
0.18
295
2270
114
690
1.72
6.50
6.2
6.9
24.1
24.6
mmol/l
0.70
107
652
139
890
1.64
6.42
2.2
3.0
66.2
66.5
g/l
0.21
124
809
87
494
1.82
6.18
2.3
1.9
1.6
1.5
g/l
0.21
73
436
983
9077
1.49
6.06
5.9
4.9
2.0
2.1
mu/l
0.31
907
8210
936
8579
1.43
5.85
24.0
16.9
38.8
39.0
%
0.35
655
5750
66
349
1.94
5.84
1.9
3.7
124.4
67.9
mg/l
0.33
53
285
66
350
1.94
5.79
1.9
3.7
37.8
42.6
mg/l
0.20
52
288
1000
9297
1.48
5.64
4.5
4.1
1.4
1.3
mmol/l
3.44
915
8393
110
694
1.64
5.39
4.4
3.7
5.2
5.2
kpa
0.12
101
652
136
905
1.57
5.35
2.4
2.5
4.8
6.8
ug/l
1.37
115
798
287
2217
1.39
5.27
1.8
1.7
1.8
1.3
mg/l
1.06
222
1716
35
151
2.36
5.20
1.2
1.4
111.3
112.6
u/ml
—
7
28
104
658
1.64
5.05
4.4
3.7
1.2
2.0
mmol/l
1.52
78
508
230
1733
1.41
4.86
1.8
1.9
—
—
—
0
0
142
976
1.52
4.84
5.6
3.7
5.7
5.8
kpa
0.44
131
949
169
1204
1.47
4.83
4.3
4.1
236.2
251.1
u/l
0.76
157
1143
91
563
1.67
4.83
3.2
3.5
4.5
4.4
pmol/l
0.26
79
495
70
404
1.78
4.76
3.1
3.3
1310.3
1070.7
u/ml
0.09
64
347
1025
9647
1.46
4.73
5.5
4.8
6.0
6.0
mmol/l
0.25
942
8693
53
281
1.93
4.70
3.5
3.0
24.3
25.2
mmol/l
0.70
45
245
140
970
1.50
4.59
5.6
3.7
1.3
1.9
mmol/l
1.25
113
776
263
2057
1.36
4.39
1.3
1.2
0.8
1.7
u/ml
1.40
50
546
445
3754
1.30
4.36
5.1
4.2
—
—
—
0
0
394
3273
1.30
4.33
2.9
3.0
2484.2
1427.2
ng/l
1.18
335
2809
113
761
1.54
4.24
1.8
1.7
—
—
—
0
0
272
2152
1.34
4.20
5.4
4.4
1.0
1.0
kg/l
0.80
55
311
57
322
1.81
4.19
2.3
2.6
38.6
37.7
g/l
0.55
51
277
328
2670
1.32
4.15
2.5
2.2
2.9
3.1
mg/l
0.59
278
2262
43
223
1.96
4.10
1.3
1.3
—
—
—
0
0
65
386
1.72
4.04
2.1
2.7
9.8
10.4
g/l
0.57
56
330
260
2055
1.34
4.03
3.5
3.1
2.5
2.5
mmol/l
0.58
225
1822
165
1219
1.41
3.88
1.7
1.8
—
—
—
0
0
59
346
1.74
3.85
2.4
2.8
1.1
1.0
g/l
0.06
53
304
67
412
1.66
3.69
2.1
2.6
7.1
7.4
g/l
0.59
52
308
467
4027
1.26
3.68
4.5
3.8
38.5
48.7
ng/l
0.50
345
2940
69
428
1.65
3.68
1.9
2.0
39.2
38.5
u/l
0.10
59
379
90
598
1.55
3.62
6.1
7.2
24.3
24.9
mmol/l
0.79
90
593
53
308
1.75
3.59
1.5
1.5
241.0
282.8
ug/g
0.60
28
184
116
815
1.47
3.58
4.7
3.0
5.0
4.5
kpa
1.36
106
787
42
228
1.87
3.54
2.1
2.2
140.9
129.3
g/l
1.81
24
174
163
1223
1.39
3.50
1.7
1.8
—
—
—
0
0
315
2603
1.29
3.49
1.6
1.5
20.8
20.7
nmol/l
0.02
275
2184
66
411
1.64
3.48
2.1
2.6
3.4
3.7
g/l
1.87
52
298
66
412
1.64
3.45
2.1
2.6
—
—
—
0
0
62
383
1.65
3.38
2.2
2.7
3.1
3.1
g/l
0.03
52
303
215
1695
1.33
3.36
3.2
3.2
0.8
0.8
mmol/l
0.03
199
1583
293
2425
1.28
3.17
4.5
4.7
23.2
21.4
%
1.16
151
1240
162
1235
1.36
3.16
3.3
2.6
1.8
1.8
%
0.12
139
1104
355
3012
1.25
3.12
5.8
5.5
3.0
3.1
ug/l
0.04
318
2661
47
276
1.73
3.10
2.1
2.4
3.5
3.7
g/l
0.36
47
264
58
365
1.62
2.97
1.3
1.2
0.3
1.1
u/ml
—
5
31
67
439
1.56
2.91
1.1
1.0
—
—
—
0
0
72
480
1.53
2.90
6.6
3.9
23.3
24.1
mmol/l
1.16
65
436
31
164
1.91
2.87
1.1
1.2
—
—
—
0
0
173
1360
1.32
2.76
1.7
1.4
—
—
—
0
0
123
920
1.38
2.72
2.1
2.1
418.0
374.3
nmol/l
1.38
111
832
8
19
4.23
2.68
2.3
1.8
1.2
1.2
mmol/l
—
8
19
38
220
1.75
2.67
1.4
1.3
—
—
—
0
0
64
427
1.53
2.59
4.7
4.2
24.2
25.1
mmol/l
1.56
59
402
252
2097
1.26
2.58
1.8
1.7
1079.7
1194.9
nmol/l
1.22
179
1563
8
20
4.02
2.57
1.1
1.1
—
—
—
0
0
36
208
1.75
2.56
1.2
1.2
24.9
7.3
u/ml
—
5
15
12
45
2.68
2.45
1.3
3.0
579.4
1107.7
u/ml
1.00
12
45
28
152
1.86
2.44
1.0
1.2
244.6
291.8
u/ml
0.52
18
91
31
174
1.80
2.43
1.2
1.2
—
—
—
0
0
42
258
1.65
2.41
1.5
1.8
14954.5
13555.6
e6/l
0.06
30
195
177
1423
1.29
2.40
26.3
27.0
1.3
1.3
inr
0.09
23
188
45
285
1.60
2.31
1.4
1.7
—
—
—
0
0
47
301
1.58
2.30
1.3
1.4
—
—
—
0
0
197
1614
1.26
2.30
1.2
1.3
3.2
14.0
u/ml
5.15
67
604
6
13
4.63
2.27
10.5
10.8
5.2
6.4
mmol/l
—
6
13
89
652
1.39
2.26
1.7
1.6
—
—
—
0
0
46
295
1.58
2.25
1.9
1.6
0.2
0.2
g/l
0.07
41
283
33
194
1.72
2.24
2.2
1.7
—
—
—
0
0
39
242
1.63
2.18
1.4
1.8
2.8
5.7
iu/l
1.99
14
79
40
252
1.61
2.11
1.3
1.2
1.3
2.7
u/ml
—
6
29
20
102
1.98
2.11
1.2
1.2
36.7
51.8
u/l
2.20
12
73
32
191
1.69
2.08
5.9
5.9
403.2
234.6
iu/ml
—
5
31
36
222
1.64
2.07
1.2
1.1
—
—
—
0
0
13
56
2.34
2.05
3.5
1.6
—
—
—
0
0
14
63
2.24
2.01
1.5
1.2
—
—
—
0
0
13
58
2.25
1.91
1.2
1.2
—
—
—
0
0
124
991
1.28
1.80
1.8
2.2
0.2
0.2
g/l
0.40
114
936
39
256
1.54
1.78
2.2
1.7
—
—
—
0
0
39
257
1.53
1.75
1.3
1.2
2.5
7.2
u/ml
—
6
46
55
390
1.43
1.73
1.9
1.7
—
—
—
0
0
198
1676
1.22
1.73
1.3
1.3
36.9
35.0
iu/ml
0.07
57
539
18
96
1.89
1.71
1.2
1.2
—
—
—
0
0
41
276
1.50
1.68
1.5
1.3
—
—
—
0
0
305
2694
1.18
1.67
1.7
1.7
1.4
1.3
mmol/l
0.72
269
2230
73
548
1.35
1.66
2.2
2.2
11.5
12.2
nmol/l
0.24
57
470
203
1730
1.21
1.66
3.0
3.3
1.0
0.8
ug/l
0.61
141
1203
22
129
1.72
1.57
2.5
1.3
—
—
—
0
0
23
137
1.69
1.56
1.5
1.6
45.7
59.5
%
0.67
15
91
58
425
1.38
1.55
2.1
1.9
—
—
—
0
0
61
451
1.37
1.54
2.0
2.0
4.2
1.9
ug/l
0.50
50
399
8
33
2.43
1.54
1.4
1.2
953.6
1839.3
miu/ml
—
8
33
34
225
1.53
1.52
1.4
1.4
—
—
—
0
0
5
15
3.34
1.52
2.0
1.1
21.8
27.2
u/l
—
5
10
0
43
0.00
1.52
0.0
1.4
—
—
—
0
0
102
818
1.27
1.47
3.3
2.7
53.3
63.1
ml/min/173m2
1.71
41
346
24
148
1.63
1.45
1.5
1.5
—
—
—
0
0
35
238
1.48
1.40
4.5
3.5
7.8
7.7
mmol/l
0.02
35
232
14
74
1.90
1.39
1.4
1.2
16.9
11.3
u/l
0.46
14
66
12
60
2.01
1.38
1.8
1.6
0.3
7.3
u/l
—
7
31
20
119
1.69
1.38
2.1
7.8
6.7
7.2
mmol/l
0.26
15
96
259
2293
1.17
1.37
1.6
1.7
71028474.8
17347369.7
pmol/l
0.54
214
1862
32
216
1.49
1.34
1.1
1.4
—
—
—
0
0
32
216
1.49
1.34
1.1
1.4
—
—
—
0
0
15
83
1.82
1.31
1.1
1.0
—
—
—
0
0
17
98
1.74
1.31
1.6
1.5
—
—
—
0
0
15
84
1.80
1.27
1.3
1.3
—
—
—
0
0
44
321
1.38
1.24
1.1
1.3
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
38
276
1.39
1.12
2.2
2.1
13.5
11.8
mg/l
0.43
33
255
15
89
1.69
1.07
2.3
2.0
1.8
1.9
u/field
—
6
35
296
2692
1.13
1.07
5.1
4.2
0.0
0.0
estimate
0.88
103
912
11
59
1.87
1.07
1.9
2.1
—
—
—
0
0
11
59
1.87
1.07
1.2
1.2
14.5
17.1
u/l
0.23
11
52
36
262
1.39
1.06
2.9
2.4
273.1
83.5
ug/min
0.64
24
152
18
114
1.59
1.03
1.1
1.4
81500.3
87864.9
e6/l
0.03
11
64
42
316
1.34
1.02
2.0
2.0
—
—
—
0
0
38
282
1.36
1.01
1.8
1.6
—
—
—
0
0
71
575
1.25
1.01
1.3
1.2
125.8
160.9
u/ml
0.36
65
525
7
35
2.01
1.00
2.0
1.1
101.7
114.5
%
—
7
28
11
61
1.81
0.98
1.2
1.1
101.1
76.8
u/l
1.18
11
55
30
215
1.41
0.98
1.2
1.4
—
—
—
0
0
31
226
1.38
0.93
1.7
1.6
—
—
—
0
0
12
70
1.72
0.92
1.5
1.4
10.1
13.5
u/l
1.33
12
65
9
52
1.74
0.92
1.2
1.2
—
—
—
0
0
17
111
1.54
0.88
6.3
2.8
—
—
—
0
0
29
212
1.38
0.87
1.3
1.2
437.8
229.2
miu/ml
—
5
91
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
45
353
1.29
0.85
2.5
2.5
0.3
0.4
u/ml
0.98
23
204
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
32
1.88
0.82
1.0
2.5
145.3
132.3
%
—
6
32
8
47
1.71
0.80
1.1
1.2
—
—
—
0
0
10
58
1.73
0.79
1.4
1.3
—
—
—
0
0
10
58
1.73
0.79
1.4
1.3
—
—
—
0
0
73
612
1.21
0.79
1.3
1.2
46.7
136.1
iu/ml
7.07
23
239
77
652
1.19
0.76
2.5
2.5
25.5
20.0
au/ml
—
5
29
28
369
0.75
0.75
2.2
2.8
—
—
—
0
0
13
83
1.57
0.75
1.0
1.2
—
—
—
0
0
12
75
1.61
0.75
1.1
1.1
—
—
—
0
0
20
141
1.43
0.74
1.9
2.5
18.1
27.0
mg/l
—
8
38
5
25
2.00
0.72
1.0
1.3
22.8
27.1
%
—
5
17
9
56
1.61
0.72
1.4
2.2
0.2
0.2
e9/l
—
9
51
161
1450
1.13
0.71
1.4
1.4
—
—
—
0
0
18
126
1.43
0.70
1.5
1.4
7006.8
1611.2
e6/l
0.87
13
86
20
148
1.36
0.60
2.8
2.9
—
2264.8
u/ml
—
0
12
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
106
943
1.14
0.59
1.5
1.7
1.4
1.5
%
1.03
88
804
15
106
1.42
0.57
1.2
1.3
511888.0
175090.1
e6/l
—
6
73
37
301
1.24
0.57
1.8
1.6
0.0
23.6
iu/ml
—
5
51
8
55
1.46
0.56
2.5
2.3
—
—
—
0
0
10
65
1.54
0.55
1.0
1.0
—
—
—
0
0
18
133
1.36
0.55
1.3
1.2
4.1
1.8
u/ml
—
8
38
143
1305
1.11
0.53
8.1
7.5
—
—
—
0
0
18
134
1.35
0.53
1.3
1.2
3.7
6.6
u/ml
0.52
12
56
18
134
1.35
0.53
1.1
1.1
—
14.8
—
0
8
6
40
1.50
0.51
1.8
2.8
—
—
—
0
0
6
40
1.50
0.51
1.8
2.8
—
—
—
0
0
28
225
1.25
0.49
4.6
4.4
5.0
5.1
kpa
0.06
28
220
7
46
1.52
0.48
1.1
1.0
—
—
—
0
0
37
312
1.19
0.43
1.3
1.4
—
—
—
0
0
9
128
0.70
0.43
1.3
1.5
—
—
—
0
0
9
129
0.70
0.43
1.3
1.5
—
—
—
0
0
9
129
0.70
0.43
1.3
1.5
—
—
—
0
0
9
130
0.69
0.43
1.3
1.5
—
—
—
0
0
9
130
0.69
0.43
1.3
1.5
—
—
—
0
0
9
130
0.69
0.43
1.3
1.5
—
—
—
0
0
11
78
1.41
0.43
1.4
1.5
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
19
149
1.28
0.42
2.2
2.2
11.6
31.2
u/ml
0.33
19
144
11
150
0.73
0.41
1.3
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
34.4
—
0
15
0
16
0.00
0.41
0.0
5.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
30
250
1.20
0.40
1.9
1.7
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.2
—
—
—
0
0
12
88
1.37
0.40
1.1
1.1
—
36.3
—
0
6
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
35
298
1.18
0.38
1.1
1.2
—
—
—
0
0
9
67
1.35
0.38
1.0
1.3
—
—
—
0
0
9
67
1.35
0.38
1.0
1.3
—
—
—
0
0
12
89
1.35
0.38
1.1
1.1
—
55.2
—
0
9
5
37
1.35
0.37
1.0
1.1
83.2
230.0
iu/ml
—
5
37
6
42
1.43
0.35
1.0
1.3
—
—
—
0
0
10
73
1.37
0.34
1.1
1.1
—
—
—
0
0
10
73
1.37
0.34
1.1
1.1
—
—
—
0
0
17
136
1.25
0.33
1.0
1.1
—
—
—
0
0
10
74
1.35
0.32
1.1
1.1
—
—
—
0
0
10
74
1.35
0.32
1.1
1.1
—
—
—
0
0
10
74
1.35
0.32
1.1
1.1
—
—
—
0
0
7
53
1.32
0.31
1.0
1.2
—
—
—
0
0
34
296
1.15
0.30
1.1
1.2
—
—
—
0
0
10
77
1.30
0.26
1.2
1.2
0.4
2.8
nmol/l
—
5
15
5
75
0.67
0.26
2.6
2.3
13.2
13.2
%
—
5
75
15
123
1.22
0.25
1.1
1.0
—
—
—
0
0
94
884
1.07
0.22
5.3
3.6
1.2
1.2
mmol/l
0.18
89
769
0
11
0.00
0.21
0.0
2.6
—
0.7
—
0
11
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.16
0.21
1.8
2.8
198.6
206.0
u/l
—
5
43
11
89
1.24
0.21
2.7
2.2
831.0
621.2
ml
—
6
55
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
50
1.20
0.19
1.0
1.4
—
—
—
0
0
13
154
0.84
0.19
1.5
1.6
—
—
—
0
0
6
52
1.15
0.19
1.0
4.6
—
33.6
—
0
8
6
53
1.13
0.18
1.0
1.4
—
—
—
0
0
6
53
1.13
0.18
1.0
1.4
—
—
—
0
0
67
629
1.07
0.18
1.6
1.5
—
—
—
0
0
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
10
82
1.22
0.17
1.2
1.4
—
—
—
0
0
61
649
0.94
0.17
2.3
1.7
—
—
—
0
0
28
253
1.11
0.17
1.3
1.6
—
—
—
0
0
19
167
1.14
0.17
1.2
1.5
—
—
—
0
0
61
573
1.07
0.16
2.0
1.7
—
—
—
0
0
11
92
1.20
0.16
1.4
2.3
—
—
—
0
0
6
76
0.79
0.15
1.3
1.5
—
—
—
0
0
25
226
1.11
0.15
3.4
2.5
17.3
16.1
%
0.80
18
117
118
1137
1.04
0.14
3.6
3.3
—
—
—
0
0
8
100
0.80
0.13
1.1
1.6
—
—
—
0
0
8
100
0.80
0.13
1.1
1.6
—
—
—
0
0
8
100
0.80
0.13
1.1
1.6
—
—
—
0
0
17
151
1.13
0.13
1.2
1.5
—
—
—
0
0
28
303
0.92
0.12
1.6
1.8
2.8
4.4
mg/l
0.38
19
223
24
260
0.92
0.11
1.2
1.3
408.6
521.1
mg/l
2.16
24
248
16
144
1.11
0.10
1.6
2.2
31.6
32.6
pg
0.36
16
144
14
125
1.12
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
2.8
4.2
—
—
—
0
0
18
164
1.10
0.09
1.8
1.3
5.3
12.6
u/l
5.33
13
126
22
203
1.09
0.09
2.3
3.6
61.5
58.8
%
0.58
22
203
28
262
1.07
0.09
1.3
1.6
—
—
—
0
0
33
311
1.06
0.09
1.1
1.6
—
—
—
0
0
7
64
1.09
0.08
1.0
1.4
—
—
—
0
0
21
195
1.08
0.08
2.3
3.2
4.3
4.3
e9/l
0.02
21
195
6
71
0.84
0.07
1.2
1.5
—
—
—
0
0
9
85
1.06
0.07
1.1
1.1
—
—
—
0
0
10
89
1.12
0.06
1.3
1.7
—
—
—
0
0
20
187
1.07
0.06
1.3
1.5
—
—
—
0
0
10
111
0.90
0.06
1.4
1.3
—
—
—
0
0
14
129
1.09
0.05
1.1
1.1
—
—
—
0
0
17
159
1.07
0.05
1.1
1.1
—
—
—
0
0
135
1332
1.01
0.04
5.3
4.7
31.7
32.8
%
0.50
95
886
13
139
0.93
0.03
2.1
1.8
91.9
89.7
%
1.90
13
139
15
141
1.06
0.03
1.3
1.5
—
—
—
0
0
19
198
0.96
0.02
1.3
1.7
—
—
—
0
0
22
228
0.96
0.02
3.4
3.8
29.5
26.8
mg/l
0.15
14
142
47
464
1.01
0.00
1.6
1.3
—
—
—
0
0
10
99
1.01
0.00
1.2
1.1
—
—
—
0
0
12
120
1.00
0.00
1.0
1.1
0.6
2.2
u/ml
—
5
47
12
120
1.00
0.00
1.1
1.7
—
—
—
0
0
52
517
1.01
0.00
1.9
1.7
—
—
—
0
0
12
122
0.98
0.00
1.3
1.7
—
—
—
0
0
11
112
0.98
0.00
2.8
3.8
—
—
—
0
0
11
112
0.98
0.00
1.1
1.7
—
—
—
0
0
11
105
1.05
0.00
1.2
1.1
—
—
—
0
0
27
274
0.98
0.00
1.5
1.5
—
—
—
0
0
5
50
1.00
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
1.3
1.3
—
53.3
—
0
9
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
6
62
0.97
0.00
1.3
1.6
—
—
—
0
0
5
49
1.02
0.00
1.2
1.3
—
—
—
0
0
8
80
1.00
0.00
1.5
1.5
—
—
—
0
0
6
63
0.95
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
7.6
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.0
1.3
—
—
—
0
0
6
61
0.98
0.00
1.3
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.3
1.8
—
—
—
0
0
6
62
0.97
0.00
1.3
3.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
59
0.85
0.00
1.2
1.2
—
—
—
0
0
7
70
1.00
0.00
1.0
1.2
—
—
—
0
0
7
72
0.97
0.00
1.6
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
2.0
1.5
0.8
1.0
g/l
—
6
66
6
62
0.97
0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
72
0.97
0.00
1.6
1.4
—
—
—
0
0
7
72
0.97
0.00
1.6
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_KIDNEY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_KIDNEY | 1.198 [1.05, 1.36] | 0.005 |
| Birth year | 0.993 [0.98, 1.0] | 0.122 |
During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 3055 females with CD2_BENIGN_KIDNEY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_KIDNEY | 1.35 [1.17, 1.56] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.041 |
During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 1946 males with CD2_BENIGN_KIDNEY died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_KIDNEY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.095% | 0.245% |
| 5 | 0.589% | 1.509% |
| 10 | 1.686% | 4.136% |
| 15 | 3.282% | 7.802% |
| 20 | 5.995% | 13.486% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_KIDNEY – Benign neoplasm: Kidney
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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