Benign neoplasm: Kidney

CD2_BENIGN_KIDNEY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D30.0&
  • Hospital discharge: ICD-9 2230
  • Hospital discharge: ICD-8 2230
  • Cause of death: ICD-10 D30.0&
  • Cause of death: ICD-9 2230
  • Cause of death: ICD-8 2230

2 out of 7 registries used, show all original rules.

1289

4. Check minimum number of events

None

1289

5. Include endpoints

None

1289

6. Filter based on genotype QC (FinnGen only)

1231

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D30
Name in latin
Neoplasma benignum renis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6609 3971 2585
Only index persons 5892 3682 2210
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.07
Only index persons 0.12 0.14 0.08
Median age at first event (years)
Whole population 63.31 61.47 66.18
Only index persons 62.69 60.74 65.94

-FinnGen-

Key figures

All Female Male
Number of individuals 1231 741 490
Unadjusted period prevalence (%) 0.25 0.26 0.22
Median age at first event (years) 62.27 59.15 66.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1289
Matched controls
12887
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
4503599627370496.0
307.7
1224
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
62.7
307.7
558
155
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
22.5
299.1
230
123
KAD00
NOMESCO Finland
Partial nephrectomy
88.1
227.5
120
15
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
45.5
156.5
93
22
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
20.9
155.4
120
63
KA1AE
NOMESCO Finland
Kidney ultrasound examination
11.5
134.7
146
141
KAC10
NOMESCO Finland
Total nephrectomy with capsule
28.0
123.0
84
32
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
23.4
97.4
71
32
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
18.4
65.7
53
30
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
16.5
63.5
54
34
N28.1
ICD-10 Finland
Cyst of kidney
9.5
63.0
76
84
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
16.7
46.2
39
24
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
45.1
43
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
45.0
257
1029
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
43.7
228
868
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.0
43.1
96
203
UKC02
NOMESCO Finland
Cystoscopy
2.6
42.2
309
1400
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.0
41.9
129
352
PC5DT
NOMESCO Finland
Embolisation of tumor of kidney
409.8
40.3
40
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
39.5
547
3249
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.5
35.3
131
405
N02AX02
ATC
tramadol; systemic, rectal
2.1
34.7
654
4303
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
9.2
33.5
41
46
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
31.1
408
2330
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
9.0
29.0
36
41
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
9.1
26.9
33
37
U14
ICPC
Kidney symptom/complaint
6.1
26.2
46
78
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
25.4
174
751
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
25.3
116
406
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
25.0
197
907
KH1AD
NOMESCO Finland
CT of urinary organs
4.0
24.9
72
187
N02BE01
ATC
paracetamol; systemic, rectal
2.9
24.6
1189
10360
22300
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
24.0
23
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
6.5
23.6
39
62
PC5ET
NOMESCO Finland
Extensive embolisation of tumor of kidney
+∞
21.9
21
*
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
7.3
21.7
32
45
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.3
21.3
55
131
KAC00
NOMESCO Finland
Nephrectomy
21.9
20.9
30
14
D30.3
ICD-10 Finland
Benign neoplasm: Bladder
37.9
20.8
26
7
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.5
19.7
131
556
XKD00
NOMESCO Finland
Uroflowmetry
2.0
19.6
241
1316
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
19.1
850
6781
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
18.9
258
1461
R31
ICD-10 Finland
Unspecified haematuria
2.2
18.8
171
831
B01AB10
ATC
tinzaparin; parenteral
2.2
17.3
162
796
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
17.3
316
1959
Z3231
NOMESCO Finland
Registered nurse
1.7
17.0
378
2480
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
16.9
76
263
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
16.8
637
4801
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
16.8
290
1765
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.9
16.5
48
125
R4110
NOMESCO Finland
Physiotherapy
1.7
16.5
382
2529
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
16.4
231
1316
8260/3-C64.9
ICD-O-3
Papillary adenocarcinoma, NOS, of kidney, NOS
21.3
16.0
23
11
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
15.2
279
1723
A02BC05
ATC
esomeprazole; systemic
1.6
15.0
540
3986
B01AB05
ATC
enoxaparin; parenteral
1.6
15.0
442
3106
JN4CD
NOMESCO Finland
Very extensive body CT
2.9
14.8
70
249
JN4BD
NOMESCO Finland
Extensive body CT
2.0
14.7
165
867
ZXA00
NOMESCO Finland
Right side
1.7
14.4
374
2537
A02BC02
ATC
pantoprazole; systemic
1.6
14.1
892
7472
WX402
NOMESCO Finland
General anaesthesia
1.8
14.0
273
1713
PC5SC
NOMESCO Finland
Selective angiography of kidney artery with X-ray
30.4
13.9
18
6
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
4.4
13.9
35
82
G04CA02
ATC
tamsulosin; oral
1.7
13.9
311
2028
ZXA05
NOMESCO Finland
Left side
1.7
13.7
349
2353
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
4.9
13.6
30
63
J01MA02
ATC
ciprofloxacin; systemic
1.6
13.5
512
3797
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.1
13.4
23
38
J01DB01
ATC
cefalexin; oral
1.7
13.4
1035
9055
N20.1
ICD-10 Finland
Calculus of ureter
3.0
13.3
60
208
JN4AD
NOMESCO Finland
Body CT examination
2.0
13.2
152
805
N18.8
ICD-10 Finland
Other chronic renal failure
3.5
13.0
45
133
S18
ICPC
Laceration/cut
1.5
12.8
600
4650
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
12.8
193
1119
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
12.7
192
1113
N20.0
ICD-10 Finland
Calculus of kidney
3.7
12.6
40
111
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
131.2
12.5
13
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.9
12.3
168
942
WX704
NOMESCO Finland
Intubation
2.2
12.3
114
556
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
37.9
12.2
15
*
KA3LT
NOMESCO Finland
Njurlesion coagulation
37.9
12.2
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
12.0
396
2827
D30.9
ICD-10 Finland
Benign neoplasm: Urinary organ, unspecified
+∞
11.5
11
*
Q85.1
ICD-10 Finland
Tuberous sclerosis
+∞
11.5
11
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
11.4
267
1752
Z3226
NOMESCO Finland
Physiotherapist
1.7
11.1
240
1541
UJF32
NOMESCO Finland
Coloscopy
1.6
11.1
352
2485
D02
ICPC
Abdominal pain epigastric
2.3
10.9
87
400
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.4
10.9
38
113
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
10.6
89
418
M54.5
ICD-10 Finland
Low back pain
1.5
10.6
431
3208
A02BC01
ATC
omeprazole; systemic
1.5
10.5
354
2530
D30.1
ICD-10 Finland
Benign neoplasm: Renal pelvis
+∞
10.4
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
10.4
485
3710
C08CA01
ATC
amlodipine; oral
1.5
10.4
510
3941
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
10.4
154
887
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
10.3
93
449
WX002
NOMESCO Finland
Sedation and analgesia
1.6
10.3
261
1741
D06
ICPC
Abdominal pain localized other
2.0
10.3
109
560
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.3
858
7352
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
10.0
150
865
D01
ICPC
Abdominal pain/cramps general
1.9
10.0
143
813
Z2221
NOMESCO Finland
Medical doctor
1.5
10.0
341
2437
R51.80
ICD-10 Finland
Headache
1.7
10.0
184
1129
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
10.0
462
3522
7125
FHL
Nephrectomy (extrrafascial)
16.8
9.9
15
9
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
4.9
9.8
21
43
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
9.7
288
1994
R39.1
ICD-10 Finland
Other difficulties with micturition
2.8
9.4
46
168
H02AB06
ATC
prednisolone; systemic
1.4
9.3
591
4769
J01EA01
ATC
trimethoprim; systemic
1.5
9.2
332
2394
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.2
9.2
36
115
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.4
9.2
33
100
205
Kela drug reimbursment
Chronic hypertension
1.5
9.0
359
2642
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
7.5
8.9
20
27
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.9
342
2498
P01AB01
ATC
metronidazole; oral, rectal
1.4
8.9
489
3833
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
3.7
8.7
27
74
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.7
438
3370
K30
ICD-10 Finland
Functional dyspepsia
1.8
8.7
144
855
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.7
504
3981
U07
ICPC
Urine symptom/complaint other
1.9
8.7
103
550
R35
ICD-10 Finland
Polyuria
2.0
8.6
94
489
R03AC02
ATC
salbutamol; inhalant
1.4
8.5
657
5460
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
8.5
331
2423
Z90.5
ICD-10 Finland
Acquired absence of kidney
20.2
8.5
12
6
KB1CG
NOMESCO Finland
Extensive MRI examination of urinary tract with high intensity magnet
90.6
8.4
9
*
TK800
NOMESCO Finland
Hemodialysis
3.2
8.4
33
106
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.4
284
2017
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
8.4
121
690
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.4
540
4343
A02BC03
ATC
lansoprazole; oral
1.5
8.3
370
2778
N03AX16
ATC
[U] pregabalin
1.5
8.3
297
2135
N30.0
ICD-10 Finland
Acute cystitis
1.6
8.2
197
1293
V03AE01
ATC
polystyrene sulfonate; oral
4.0
8.2
23
59
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
3.2
8.1
32
103
U79
ICPC
Neoplasm urinary tract unspecified
33.6
8.1
10
*
C64.80
ICD-10 Finland
Wilms tumour
22.2
8.0
11
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
8.0
212
1426
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
3.7
7.9
24
65
J01FA10
ATC
azithromycin; systemic
1.4
7.9
652
5451
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.9
457
3595
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
13.1
7.9
13
10
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
9.5
7.8
15
16
KA1AE, ,
SPAT
15.1
7.7
12
8
KA4AT
NOMESCO Finland
Cytology of kidney with ultrasound guidance
45.2
7.7
9
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.8
7.6
23
62
J01AA02
ATC
doxycycline; systemic
1.5
7.6
967
8682
ZXE00
NOMESCO Finland
One hour or less
1.4
7.6
465
3687
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
18.5
7.6
11
6
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.0
7.6
76
383
C08CA13
ATC
lercanidipine; oral
1.6
7.6
192
1276
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.3
190
1270
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
7.3
164
1058
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
7.3
107
614
J01FA09
ATC
clarithromycin; systemic
1.4
7.3
358
2728
JFB00
NOMESCO Finland
Partial resection of small intestine
3.4
7.3
25
74
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
7.2
129
784
KA6KT
NOMESCO Finland
Sclerotherapy of kidney cyst
30.2
7.2
9
*
N19
ICD-10 Finland
Unspecified kidney failure
2.3
7.1
52
232
C09CA01
ATC
losartan; oral
1.4
7.0
322
2419
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.4
7.0
45
189
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
3.3
7.0
25
76
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.7
7.0
35
130
L15
ICPC
Knee symptom/complaint
1.5
6.9
290
2143
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.8
6.9
106
617
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
6.8
78
413
C07AB07
ATC
bisoprolol; oral
1.4
6.7
622
5245
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
6.7
89
494
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.1
6.7
59
284
R05
ICD-10 Finland
Cough
1.5
6.6
249
1801
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
6.6
42
176
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
6.6
255
1855
J02AC01
ATC
fluconazole; systemic
1.4
6.6
445
3572
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
3.8
6.5
19
50
R06AX27
ATC
desloratadine; oral
1.4
6.5
295
2208
SPAT1153
SPAT
Removal of sutures
1.4
6.5
396
3122
C09CA06
ATC
candesartan; oral
1.4
6.4
279
2072
TQW99
NOMESCO Finland
Other minor procedure on skin
1.9
6.4
73
386
L05
ICPC
Flank/axilla symptom/complaint
1.9
6.4
78
423
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
6.3
128
804
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
6.3
152
997
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.6
6.3
35
137
C09CA03
ATC
valsartan; oral
1.7
6.3
120
742
PC5NT
NOMESCO Finland
Endovascular embolisation for kidney bleeding with radiological guidance
+∞
6.3
6
*
M03BX02
ATC
tizanidine; oral
1.3
6.2
710
6152
XJH00
NOMESCO Finland
Transanal ultrasonography
1.9
6.2
78
426
L03
ICPC
Low back symptom/complaint
1.4
6.2
316
2414
KCD02
NOMESCO Finland
Transurethral resection of bladder
2.6
6.1
34
133
R01AD58
ATC
fluticasone, combinations; nasal
1.5
6.1
242
1764
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.1
174
1186
R03BA01
ATC
beclometasone; inhalant
1.6
6.1
163
1095
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.8
6.1
18
48
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.1
503
4151
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
3.1
6.1
25
83
JEA01
NOMESCO Finland
Laparoscopic appendectomy
2.4
6.1
38
158
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
6.1
187
1297
R52.9
ICD-10 Finland
Pain, unspecified
1.7
6.1
118
734

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1075
8546
2.55
35.08
8.8
7.7
80.17
78.95
u/l
0.34
1035
8019
976
7496
2.24
33.62
5.7
4.5
—
—
—
0
0
815
5878
2.05
32.71
6.1
6.2
10.72
11.45
umol/l
1.43
773
5571
706
4903
1.97
30.78
5.8
4.8
35.60
35.17
g/l
1.31
666
4561
533
3392
1.97
29.70
4.3
3.3
89.70
87.47
e6/l
0.01
418
2647
784
5689
1.96
29.54
9.0
6.8
1.22
1.21
mmol/l
0.45
691
4844
746
5379
1.92
28.00
15.1
16.6
1.22
1.29
inr
1.41
187
1565
221
1028
2.39
27.52
1.4
1.4
—
—
—
0
0
584
3918
1.90
27.07
5.0
3.8
87.96
94.62
e6/l
0.07
443
2848
927
7248
1.99
26.60
6.2
4.7
1508.30
2245.62
e6/l
—
10
125
718
5195
1.86
25.78
7.7
5.9
1.22
1.21
mmol/l
1.32
665
4725
483
3100
1.89
25.22
4.2
3.2
0.18
0.48
e6/l
6.52
385
2386
712
5190
1.83
24.43
3.0
2.6
—
—
—
0
0
468
3001
1.88
24.30
4.1
3.1
—
—
—
0
0
527
3521
1.84
23.91
2.7
2.5
60.97
82.94
u/l
0.47
482
3238
314
1793
1.99
22.87
3.5
3.0
1.64
2.57
e6/l
1.94
181
1007
330
1919
1.97
22.80
3.2
2.8
1.00
1.13
e6/l
0.21
196
1124
375
2290
1.90
22.31
3.7
2.9
522.87
538.49
mosm/kgh2o
0.76
321
1973
273
1510
2.02
21.62
8.0
5.4
1.05
1.03
mmol/l
0.83
253
1381
106
386
2.90
21.51
2.4
3.2
0.30
0.28
g/l
0.10
49
147
190
918
2.25
21.35
5.3
3.7
101.40
88.08
ng/l
0.98
169
796
381
2398
1.84
20.28
3.3
2.6
4.02
5.99
e6/l
3.57
342
2164
140
614
2.44
19.59
7.3
9.7
—
—
—
0
0
807
6333
1.73
19.40
9.0
9.2
4.31
4.09
e9/l
1.64
699
5563
611
4491
1.68
18.34
2.4
2.2
—
—
—
0
0
505
3552
1.69
17.73
2.9
2.5
—
—
—
0
0
675
5121
1.67
17.72
6.0
5.8
58.29
57.55
%
0.90
636
4784
192
1002
2.08
17.57
9.5
7.2
10.74
9.92
mmol/l
0.89
184
955
1186
10630
2.44
17.52
19.5
15.4
27.51
24.56
mg/l
1.80
997
8512
818
6537
1.69
17.46
5.6
4.8
6.72
6.75
mmol/l
0.17
785
6159
682
5206
1.66
17.33
6.2
6.1
26.71
27.35
%
0.79
643
4865
617
4598
1.66
17.18
2.7
2.2
78.78
78.77
nmol/l
0.01
562
4074
670
5103
1.65
17.08
6.5
6.3
8.48
8.68
%
0.94
631
4759
667
5080
1.65
16.96
6.1
5.9
2.92
2.80
%
0.65
626
4736
205
1113
2.00
16.78
6.6
7.9
122.44
120.10
g/l
1.00
199
1086
503
3590
1.66
16.36
4.2
3.8
17.15
8.55
mg/mmol
2.28
338
2226
647
4929
1.63
16.13
6.0
5.9
0.71
0.67
%
1.11
607
4591
486
3450
1.66
16.07
3.4
3.3
30.18
32.28
u/l
1.03
462
3280
215
1206
1.94
15.97
6.5
7.5
95.81
95.53
%
0.24
206
1164
1217
11111
2.70
15.94
23.7
17.8
139.71
139.67
mmol/l
0.19
1202
10812
1218
11138
2.69
15.65
24.1
17.9
3.98
3.98
mmol/l
0.30
1199
10827
960
8113
1.72
15.57
4.6
4.2
13.17
13.13
mm/h
0.03
896
7458
475
3386
1.64
15.26
3.4
3.2
319.23
346.12
mg/l
0.05
318
2126
564
4194
1.61
15.24
4.2
3.6
5.93
5.83
ph
0.26
34
257
229
1335
1.87
15.07
6.1
7.2
5.19
5.12
kpa
0.56
218
1283
229
1336
1.87
15.03
6.1
7.2
12.54
12.11
kpa
0.66
219
1284
488
3513
1.63
15.01
3.4
3.1
6.76
7.23
mmol/l
1.75
418
2929
229
1342
1.86
14.80
6.1
7.2
0.47
1.26
mmol/l
3.00
187
1077
394
2698
1.66
14.72
2.5
2.4
—
—
—
0
0
675
5286
1.58
14.35
6.7
5.3
0.00
0.00
estimate
0.50
119
1010
529
3918
1.59
14.26
3.6
3.5
2.37
2.35
mmol/l
1.42
457
3440
674
5282
1.58
14.24
4.7
3.9
0.00
0.00
estimate
0.75
131
1083
704
5605
1.56
13.64
6.2
6.0
0.20
0.19
e9/l
1.38
612
4922
677
5351
1.56
13.48
4.8
3.9
0.00
0.01
estimate
0.80
115
984
46
135
3.50
13.38
1.3
1.2
—
—
nmol/l
—
0
0
695
5532
1.56
13.37
6.0
5.8
1.85
1.93
e9/l
0.56
614
4894
494
3642
1.58
13.35
3.7
3.2
—
—
—
0
0
465
3389
1.58
13.16
5.9
4.0
7.39
7.40
ph
1.00
72
663
440
3166
1.59
13.15
4.6
4.3
—
—
—
0
0
647
5082
1.55
13.11
6.4
6.4
—
—
—
0
0
179
1007
1.90
13.05
2.5
2.3
53.19
37.02
u/l
0.62
161
862
49
153
3.29
12.96
1.4
1.3
0.22
0.49
nmol/l
—
5
12
681
5421
1.54
12.91
6.0
5.8
0.04
0.04
e9/l
1.93
584
4697
49
154
3.27
12.82
1.4
1.3
0.64
0.63
nmol/l
0.11
49
145
678
5413
1.53
12.53
6.0
5.7
0.60
0.58
e9/l
0.99
583
4684
321
2165
1.64
12.40
4.3
3.8
143.98
323.73
ng/l
1.96
264
1731
46
143
3.30
12.26
1.4
1.2
—
—
—
0
0
104
491
2.22
12.21
2.7
2.7
—
—
—
0
0
1032
9094
1.67
12.10
24.7
18.3
15.25
15.15
%
0.19
1022
8931
1192
10989
2.12
11.74
19.4
14.7
—
—
—
0
0
251
1613
1.69
11.60
3.6
2.5
2.34
2.31
g/l
0.31
238
1498
807
6758
1.52
11.43
3.6
3.2
61.41
50.65
u/l
1.25
763
6233
354
2489
1.58
11.38
4.1
3.9
—
—
—
0
0
238
1520
1.69
11.23
3.8
2.5
21.11
22.53
%
0.80
197
1291
597
4727
1.49
10.92
2.3
2.0
96.57
95.13
pmol/l
0.30
305
2391
578
4554
1.49
10.80
3.3
2.8
130.04
131.24
ug/l
0.05
541
4164
199
1228
1.73
10.61
2.9
2.7
6.03
8.86
umol/l
2.37
180
1076
161
941
1.81
10.32
8.7
7.8
—
—
—
0
0
97
487
2.07
9.75
5.0
5.2
0.90
0.90
%
0.02
92
462
97
489
2.06
9.64
5.0
5.2
1.63
1.59
%
0.14
92
463
259
1759
1.59
9.45
3.7
2.5
11.94
12.78
umol/l
0.98
247
1636
1207
11306
2.06
9.35
13.1
11.0
26.32
25.07
u/l
1.46
1178
10867
1147
10589
1.75
9.09
5.1
4.6
4.60
4.63
mmol/l
0.48
1070
9716
1140
10511
1.73
9.02
5.1
4.6
1.45
1.49
mmol/l
2.77
1054
9570
1097
10016
1.64
8.99
7.2
6.0
40.39
40.22
mmol/mol
0.24
1024
9194
938
8299
1.48
8.66
4.7
4.1
14.82
14.89
pmol/l
0.38
861
7491
181
1149
1.67
8.62
2.3
2.2
121.72
135.52
ug/g
0.27
147
904
136
807
1.77
8.26
2.1
2.8
—
—
—
0
0
1160
10797
1.74
8.21
5.9
5.2
2.70
2.71
mmol/l
0.26
1075
9839
1229
11669
2.14
7.88
30.5
22.9
39.36
39.65
%
0.80
1145
10852
1229
11669
2.14
7.88
30.5
22.8
254.22
249.31
e9/l
1.72
1211
11352
59
265
2.28
7.86
5.9
7.1
106.67
105.41
mmol/l
0.92
54
243
59
265
2.28
7.86
5.9
7.1
11.33
11.09
mmol/l
0.18
54
243
1083
9934
1.56
7.84
5.9
4.9
2.00
2.09
mu/l
0.27
996
9005
1229
11671
2.13
7.84
30.3
22.7
90.88
91.41
fl
3.99
1222
11475
1229
11672
2.13
7.82
30.2
22.7
30.13
30.36
pg
4.52
1222
11474
1229
11672
2.13
7.82
30.3
22.8
6.93
6.71
e9/l
2.54
1205
11313
1229
11673
2.13
7.80
30.3
22.8
4.42
4.43
e12/l
0.34
1203
11317
158
995
1.67
7.74
2.9
2.9
147.92
213.31
ng/l
1.42
145
914
1229
11677
2.12
7.73
30.6
22.9
132.13
133.66
g/l
3.26
1222
11480
159
1004
1.67
7.71
6.7
6.6
1.13
1.38
mmol/l
4.27
152
981
125
747
1.75
7.41
4.0
3.7
5.11
5.17
kpa
0.37
120
722
436
3437
1.41
7.33
2.5
2.1
151.90
247.81
u/l
2.05
414
3230
29
95
3.10
7.19
5.5
4.8
238.83
44.21
u/ml
0.40
11
26
375
2888
1.42
7.17
2.9
2.7
7005.52
5921.66
umol/l
0.14
323
2490
150
951
1.65
7.15
2.2
3.0
66.01
66.51
g/l
0.35
135
869
72
367
2.02
7.00
5.7
6.4
1.28
1.33
mmol/l
0.15
66
325
1098
10169
1.54
6.89
4.6
4.1
1.37
1.28
mmol/l
3.64
1004
9183
94
529
1.84
6.82
2.2
1.9
1.63
1.50
g/l
0.61
80
463
72
372
1.99
6.75
1.9
3.8
121.39
67.63
mg/l
0.33
55
303
72
373
1.98
6.70
1.9
3.8
36.94
43.27
mg/l
0.30
54
306
574
4787
1.36
6.66
11.0
9.8
0.00
0.00
e9/l
1.40
469
3939
121
739
1.70
6.65
4.1
3.7
7.39
7.41
ph
0.44
13
98
125
775
1.68
6.50
1.2
1.2
—
—
—
0
0
1127
10531
1.56
6.42
5.5
4.8
6.01
5.98
mmol/l
0.32
1035
9497
268
1979
1.45
6.36
1.5
1.5
2.23
2.50
g/l
1.60
154
1189
208
1463
1.50
6.32
1.4
1.3
—
—
—
0
0
183
1257
1.53
6.21
3.4
4.0
3.92
21.91
ug/l
2.01
133
1036
167
1127
1.55
6.14
1.8
1.5
—
—
—
0
0
355
2777
1.38
6.04
7.3
6.7
—
—
—
0
0
30
113
2.69
5.85
1.4
1.6
—
—
—
0
0
102
618
1.71
5.79
3.1
3.4
4.47
4.42
pmol/l
0.15
90
541
180
1251
1.51
5.77
1.8
1.7
—
—
—
0
0
359
2838
1.37
5.67
4.5
3.6
—
—
—
0
0
311
2406
1.39
5.60
1.8
1.7
1.74
1.28
mg/l
0.87
242
1855
292
2252
1.38
5.34
1.3
1.2
1.67
1.57
u/ml
0.04
58
598
20
63
3.21
5.33
6.8
6.5
—
—
—
0
0
117
754
1.61
5.25
6.1
7.0
24.13
24.62
mmol/l
0.61
111
718
857
7739
1.32
5.12
4.3
4.0
—
—
—
0
0
216
1594
1.43
5.08
1.3
1.2
—
—
—
0
0
426
3503
1.32
5.07
2.8
3.0
2310.58
1389.11
ng/l
1.08
364
3006
284
2197
1.37
5.07
3.4
3.0
2.46
2.46
mmol/l
0.37
247
1949
153
1057
1.51
5.05
5.5
3.6
5.74
5.82
kpa
0.46
142
1028
357
2865
1.34
5.02
2.5
2.2
2.87
3.07
mg/l
0.84
304
2432
37
169
2.22
4.84
1.2
1.4
107.00
138.16
u/ml
—
8
32
220
1649
1.40
4.73
2.1
2.1
—
—
—
0
0
53
281
1.92
4.69
1.8
4.0
—
—
—
0
0
191
1398
1.43
4.69
1.5
1.3
407.69
573.20
titre
1.41
52
297
150
1052
1.48
4.60
5.6
3.6
1.36
2.00
mmol/l
1.30
125
870
61
341
1.83
4.60
3.2
3.3
—
—
—
0
0
40
193
2.11
4.59
1.3
1.4
—
—
—
0
0
101
650
1.60
4.58
1.5
1.8
1.54
1.40
g/l
0.16
92
595
141
986
1.48
4.40
1.9
1.5
—
—
—
0
0
117
787
1.53
4.39
4.6
4.8
—
—
—
0
0
64
370
1.77
4.34
1.6
1.6
—
—
—
0
0
69
409
1.73
4.29
2.1
2.8
9.67
10.43
g/l
0.87
63
366
141
994
1.47
4.23
2.3
2.5
4.76
6.89
ug/l
1.70
118
877
293
2340
1.33
4.18
5.3
4.3
1.02
1.02
kg/l
0.62
60
349
59
337
1.79
4.18
2.3
2.6
38.72
37.75
g/l
0.68
53
295
100
657
1.57
4.17
6.5
7.4
24.22
24.91
mmol/l
1.06
100
652
508
4363
1.27
4.15
4.4
3.8
40.29
48.08
ng/l
0.36
375
3166
341
2786
1.30
4.12
1.6
1.5
21.04
20.74
nmol/l
0.13
294
2337
141
1002
1.46
4.06
2.1
2.1
409.44
372.85
nmol/l
1.17
128
906
73
450
1.66
3.96
3.1
3.3
1252.22
3172.17
u/ml
0.38
67
390
85
545
1.60
3.94
4.2
3.9
—
—
—
0
0
126
884
1.47
3.88
4.5
3.0
4.92
4.50
kpa
1.35
116
854
46
250
1.87
3.83
2.1
2.2
138.64
128.61
g/l
1.57
28
191
94
622
1.55
3.82
1.4
1.4
—
—
—
0
0
167
1243
1.39
3.73
1.3
1.3
—
—
—
0
0
73
458
1.63
3.71
4.2
4.2
24.10
24.98
mmol/l
1.83
67
431
176
1327
1.38
3.64
3.1
2.7
1.78
1.83
%
0.31
151
1187
46
255
1.83
3.62
1.5
1.8
2.79
5.51
iu/l
2.07
17
83
117
821
1.47
3.61
2.2
3.0
10.07
10.82
g/l
0.91
104
747
55
325
1.72
3.51
1.5
1.5
243.80
287.96
ug/g
0.68
30
195
28
132
2.15
3.47
1.3
1.1
—
—
—
0
0
173
1314
1.37
3.42
2.0
1.6
—
—
—
0
0
390
3309
1.26
3.39
5.9
5.4
2.91
3.04
ug/l
0.10
346
2924
89
600
1.52
3.35
2.0
2.2
11.52
12.19
nmol/l
0.26
69
518
21
89
2.38
3.32
1.1
1.1
—
—
—
0
0
144
1075
1.38
3.18
1.8
2.2
0.21
0.21
g/l
0.39
133
1016
27
131
2.08
3.13
1.3
1.2
—
—
—
0
0
31
160
1.96
3.06
1.1
1.1
—
—
—
0
0
230
1852
1.29
3.04
3.2
3.1
0.81
0.82
mmol/l
0.13
214
1737
87
598
1.49
3.01
4.9
3.8
—
—
—
0
0
31
162
1.94
2.96
1.1
1.0
—
—
—
0
0
25
121
2.09
2.93
3.0
3.3
—
—
—
0
0
13
46
2.84
2.92
1.3
3.0
550.62
1088.48
u/ml
1.07
13
46
51
315
1.64
2.82
1.8
1.6
0.23
0.24
g/l
0.11
46
300
43
255
1.71
2.77
1.2
1.2
—
—
—
0
0
5
6
8.36
2.75
1.0
1.2
—
—
—
0
0
61
397
1.56
2.74
1.3
1.2
0.32
1.02
u/ml
—
5
32
216
1752
1.28
2.70
1.3
1.3
3.04
13.36
u/ml
5.41
72
660
87
614
1.45
2.66
2.5
2.5
—
—
—
0
0
268
2235
1.25
2.65
1.9
1.7
1065.58
1195.68
nmol/l
1.56
194
1666
71
483
1.50
2.62
2.6
1.9
—
—
—
0
0
98
715
1.40
2.51
2.6
3.1
7.09
5.44
e9/l
0.33
82
568
33
187
1.78
2.50
1.3
1.3
—
—
—
0
0
33
187
1.78
2.50
1.3
1.3
—
—
—
0
0
51
326
1.59
2.49
4.5
4.9
—
—
—
0
0
44
273
1.63
2.43
1.3
1.2
1.32
2.61
u/ml
—
6
31
166
1323
1.29
2.38
1.4
1.4
—
—
—
0
0
24
126
1.92
2.31
1.3
1.6
—
—
—
0
0
21
105
2.02
2.31
1.7
1.9
—
—
—
0
0
32
185
1.75
2.29
1.3
1.3
—
—
—
0
0
106
797
1.36
2.29
1.4
1.4
—
—
—
0
0
37
224
1.67
2.26
3.3
2.6
—
—
—
0
0
32
186
1.74
2.25
1.3
1.3
—
—
—
0
0
5
9
5.57
2.21
1.0
1.2
—
—
—
0
0
11
41
2.70
2.21
3.6
2.5
—
—
—
0
0
38
234
1.64
2.18
5.5
3.7
—
—
—
0
0
126
981
1.31
2.17
1.6
1.5
—
—
—
0
0
6
14
4.30
2.15
10.5
11.5
5.22
6.10
mmol/l
—
6
14
30
174
1.74
2.14
1.1
1.2
247.53
277.90
u/ml
0.32
19
101
146
1162
1.29
2.14
6.3
4.4
—
—
—
0
0
219
1832
1.24
2.10
1.3
1.3
53.31
35.58
iu/ml
0.43
66
609
85
626
1.38
2.10
1.3
1.2
117.68
153.49
u/ml
0.46
79
572
225
1894
1.23
2.04
3.1
3.3
1.00
0.79
ug/l
0.72
156
1308
317
2763
1.19
2.01
1.3
1.4
—
—
—
0
0
68
487
1.42
1.99
1.9
2.0
3.77
1.82
ug/l
0.45
57
435
15
71
2.13
1.92
2.3
3.9
—
—
—
0
0
23
128
1.81
1.90
2.2
7.3
6.91
7.24
mmol/l
0.17
18
103
44
292
1.52
1.89
2.7
2.2
228.82
84.06
ug/min
0.58
29
166
126
1001
1.29
1.89
2.9
2.7
68.38
71.06
e9/l
0.50
94
783
16
79
2.04
1.85
1.4
1.1
38.00
91.54
titre
—
5
13
44
294
1.51
1.84
2.2
2.1
13.17
11.75
mg/l
0.43
39
271
24
137
1.77
1.84
1.3
1.3
—
—
—
0
0
43
286
1.52
1.84
1.5
1.7
14919.88
13794.20
e6/l
0.05
32
216
29
175
1.67
1.83
1.2
1.2
—
—
—
0
0
12
54
2.23
1.74
1.1
1.0
—
—
—
0
0
8
30
2.68
1.72
1.8
1.8
66.75
88.77
nmol/24h
—
8
30
331
2933
1.17
1.71
1.7
1.7
1.42
1.34
mmol/l
0.78
291
2434
28
171
1.65
1.71
1.3
1.3
—
—
—
0
0
6
19
3.17
1.66
1.0
1.0
—
—
—
0
0
6
19
3.17
1.66
1.0
1.1
—
—
—
0
0
118
952
1.26
1.59
3.9
3.5
—
—
—
0
0
11
50
2.21
1.57
1.1
1.0
—
—
—
0
0
17
92
1.86
1.56
1.1
1.2
—
—
—
0
0
15
78
1.93
1.54
1.3
1.1
—
—
—
0
0
0
42
0.00
1.52
0.0
1.2
—
14.22
—
0
30
6
21
2.86
1.50
1.0
1.4
—
—
—
0
0
6
21
2.86
1.50
1.5
2.4
150.00
195.71
e6/l
—
6
7
34
226
1.52
1.50
1.4
1.5
0.92
0.83
nmol/l
0.28
29
183
31
202
1.55
1.49
4.6
2.6
—
—
—
0
0
13
65
2.01
1.49
1.1
1.1
—
—
—
0
0
37
251
1.49
1.49
4.7
2.9
—
—
—
0
0
91
718
1.29
1.48
1.3
1.3
—
—
—
0
0
9
37
2.44
1.48
1.3
1.1
1182.44
1876.43
miu/ml
—
9
37
66
498
1.34
1.47
1.3
1.2
—
—
—
0
0
15
80
1.88
1.45
1.5
1.2
16.73
11.21
u/l
0.49
15
72
38
261
1.47
1.44
4.7
3.4
7.72
7.69
mmol/l
0.01
38
254
17
95
1.80
1.43
2.2
2.0
2.00
1.74
u/field
—
8
39
9
40
2.26
1.40
1.2
1.4
5.09
3.69
mmol/l
—
9
35
39
272
1.45
1.38
1.2
1.8
—
—
—
0
0
5
17
2.95
1.36
1.6
1.7
—
—
—
0
0
29
191
1.53
1.35
1.4
1.5
—
—
—
0
0
0
38
0.00
1.34
0.0
1.1
—
—
—
0
0
16
90
1.79
1.33
1.3
1.4
2.58
2.83
g/l
0.21
11
60
16
90
1.79
1.33
1.3
1.4
6.48
7.41
g/l
0.42
11
61
16
90
1.79
1.33
1.3
1.4
0.26
0.38
g/l
—
10
59
89
713
1.27
1.31
2.5
2.5
18.22
23.43
au/ml
—
6
47
24
153
1.58
1.29
1.5
1.6
51.29
60.13
%
0.40
17
99
44
319
1.39
1.28
1.1
1.1
—
—
—
0
0
127
1063
1.22
1.27
1.6
1.6
—
—
—
0
0
5
117
0.43
1.25
1.0
1.3
—
—
—
0
0
41
296
1.40
1.23
3.6
2.6
—
—
—
0
0
12
63
1.91
1.23
1.6
3.0
—
—
—
0
0
16
93
1.73
1.21
1.3
1.4
—
—
—
0
0
104
858
1.23
1.20
4.1
4.4
0.17
0.44
%
0.34
24
249
13
71
1.84
1.19
1.6
3.5
7.44
7.42
ph
—
6
21
6
26
2.31
1.18
1.3
1.5
—
—
—
0
0
19
117
1.63
1.18
1.4
1.6
—
—
—
0
0
16
94
1.71
1.17
2.6
2.2
760.18
629.28
ml
0.40
11
57
116
972
1.21
1.16
3.8
4.2
0.69
0.99
%
0.69
35
362
33
233
1.43
1.13
1.3
1.3
464.14
227.85
miu/ml
—
7
96
275
2478
1.14
1.13
1.6
1.7
66087397.34
18024263.71
pmol/l
0.51
230
2014
24
159
1.52
1.12
1.3
1.2
—
—
—
0
0
13
74
1.76
1.07
1.2
1.9
—
—
—
0
0
16
97
1.66
1.07
1.3
1.3
—
—
—
0
0
90
743
1.23
1.06
3.9
3.1
—
—
—
0
0
7
33
2.13
1.05
1.3
1.5
—
—
—
0
0
14
82
1.71
1.05
1.5
1.4
—
—
—
0
0
71
573
1.25
1.03
1.3
1.2
—
—
—
0
0
19
123
1.55
1.00
1.4
1.3
293.21
276.25
mosm/kgh2o
0.88
14
89
31
223
1.40
0.99
1.4
1.6
—
—
—
0
0
11
61
1.81
0.98
1.9
2.3
0.24
0.22
e9/l
0.18
11
56
25
173
1.45
0.98
1.4
1.4
—
—
—
0
0
108
917
1.19
0.97
3.9
4.3
0.07
0.11
%
0.31
27
306
15
92
1.64
0.97
1.1
1.3
—
—
—
0
0
23
157
1.47
0.96
1.7
1.7
0.76
0.92
g/l
0.18
18
117
12
70
1.72
0.92
1.9
1.5
—
—
—
0
0
6
28
2.15
0.91
1.3
1.0
—
—
—
0
0
104
887
1.19
0.90
3.8
4.0
0.61
0.68
%
0.12
28
306
65
529
1.24
0.90
1.6
1.5
—
—
—
0
0
370
3440
1.11
0.89
5.2
4.1
—
—
—
0
0
6
29
2.07
0.89
1.3
1.9
—
—
—
0
0
316
2915
1.11
0.88
5.0
4.2
0.00
0.01
estimate
1.08
114
978
16
103
1.56
0.87
1.3
1.2
—
—
—
0
0
6
30
2.00
0.87
1.2
1.3
22.67
27.95
%
—
6
22
6
30
2.00
0.87
1.5
1.2
—
—
—
0
0
19
128
1.49
0.86
1.2
1.4
87208.58
77798.84
e6/l
0.06
12
73
6
112
0.53
0.83
1.5
1.1
—
—
—
0
0
16
105
1.53
0.81
1.3
1.4
18.91
32.33
u/l
0.96
11
88
15
97
1.55
0.81
2.3
2.5
—
—
—
0
0
18
122
1.48
0.80
2.2
2.6
2.35
1.16
g/24h
0.65
12
59
80
676
1.20
0.79
1.3
1.2
46.70
135.71
iu/ml
7.33
23
262
12
75
1.61
0.75
1.1
1.1
—
—
—
0
0
7
38
1.85
0.73
1.6
2.8
—
—
—
0
0
5
25
2.00
0.72
1.4
1.1
—
—
—
0
0
10
60
1.67
0.72
1.1
1.7
—
—
—
0
0
5
26
1.93
0.70
2.6
4.7
—
—
—
0
0
32
248
1.30
0.69
6.4
4.4
8.72
8.24
kpa
0.91
32
243
7
42
1.67
0.68
1.0
1.1
—
—
—
0
0
9
59
1.53
0.68
1.6
1.4
—
5.00
%
—
0
12
80
689
1.17
0.66
1.4
1.3
—
—
—
0
0
18
128
1.41
0.65
1.3
2.2
—
—
—
0
0
10
62
1.62
0.65
1.4
1.2
—
—
—
0
0
5
29
1.73
0.64
1.8
2.3
140.80
149.29
nmol/l
—
5
24
17
121
1.41
0.62
1.5
1.4
—
—
—
0
0
9
138
0.65
0.60
1.2
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
23.52
—
0
14
8
52
1.54
0.59
13.6
13.6
—
—
—
0
0
31
246
1.27
0.58
6.3
4.4
2.83
2.70
mmol/l
0.09
23
169
13
89
1.47
0.58
1.1
1.4
—
31.71
—
0
7
24
184
1.31
0.58
1.6
1.3
5.14
12.15
u/l
6.09
16
141
31
247
1.26
0.57
6.3
4.4
5.05
5.06
kpa
0.04
31
242
9
61
1.48
0.53
2.8
2.6
—
—
—
0
0
6
39
1.54
0.53
1.2
1.1
93.67
223.18
iu/ml
—
6
39
6
39
1.54
0.53
2.0
1.4
—
—
—
0
0
19
143
1.33
0.52
1.5
1.4
6748.07
1666.92
e6/l
0.90
14
101
6
40
1.50
0.51
1.7
1.2
134.33
164.81
pmol/l
—
6
40
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
24
190
1.27
0.48
1.0
1.4
—
—
—
0
0
7
47
1.49
0.47
1.3
1.3
128.86
166.84
mmol/24h
—
7
47
7
47
1.49
0.47
3.9
3.7
—
—
—
0
0
106
961
1.11
0.46
5.6
3.7
1.23
1.23
mmol/l
0.64
100
833
17
129
1.32
0.45
2.2
2.7
—
—
—
0
0
338
3537
0.94
0.44
3.4
3.0
—
—
—
0
0
11
78
1.41
0.43
2.0
2.0
2.69
3.09
ug/l
0.20
11
70
28
338
0.82
0.42
8.5
11.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
50.13
—
0
15
0
15
0.00
0.41
0.0
1.1
—
875.68
—
0
5
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
27
223
1.21
0.39
2.5
3.6
61.70
58.55
%
0.81
27
223
8
61
1.31
0.39
1.6
1.3
—
—
—
0
0
19
151
1.26
0.38
1.3
1.2
3.75
6.20
u/ml
0.49
12
64
9
68
1.33
0.37
1.9
1.3
—
—
—
0
0
13
98
1.33
0.37
1.1
1.1
—
83.87
—
0
6
11
81
1.36
0.36
1.2
1.1
0.43
4.38
nmol/l
—
5
16
9
71
1.27
0.36
2.8
2.3
—
—
—
0
0
38
329
1.16
0.35
1.1
1.2
—
—
—
0
0
9
125
0.72
0.35
1.0
1.1
—
—
—
0
0
12
91
1.32
0.33
2.2
3.1
10.60
10.85
%
0.08
12
91
27
228
1.19
0.33
1.1
1.2
—
—
—
0
0
6
87
0.69
0.33
2.8
2.2
13.17
13.20
%
—
6
87
29
247
1.18
0.33
3.4
2.4
17.09
16.06
%
0.79
22
127
42
371
1.14
0.31
3.9
4.0
3.86
3.92
mmol/l
0.36
42
365
10
75
1.34
0.30
2.0
1.6
42.79
38.47
%
—
10
75
15
120
1.25
0.30
1.2
1.3
511888.00
167011.24
e6/l
—
6
78
60
546
1.10
0.28
4.5
2.6
0.64
0.64
%
0.01
60
541
10
129
0.77
0.28
1.0
1.1
—
—
—
0
0
8
63
1.27
0.27
1.0
1.0
—
—
—
0
0
8
64
1.25
0.27
1.4
2.0
11.83
9.45
mmol/l
—
8
64
25
215
1.17
0.26
2.6
3.3
4.44
4.28
e9/l
0.18
25
215
87
934
0.93
0.26
5.1
3.9
—
—
—
0
0
24
207
1.16
0.25
1.8
1.6
—
—
—
0
0
9
75
1.20
0.25
1.3
2.7
—
—
—
0
0
17
142
1.20
0.24
1.1
1.2
—
—
—
0
0
5
38
1.32
0.23
2.2
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
10.80
—
0
5
0
12
0.00
0.21
0.0
1.0
—
173.20
—
0
5
5
43
1.16
0.21
2.8
2.5
42360.00
38986.16
ug/l
—
5
43
33
297
1.11
0.20
1.2
1.1
—
—
—
0
0
10
123
0.81
0.20
1.0
1.1
—
—
—
0
0
29
259
1.12
0.20
1.1
1.2
—
—
—
0
0
50
461
1.09
0.20
4.8
4.4
—
—
—
0
0
73
685
1.07
0.19
1.3
1.4
—
—
—
0
0
25
222
1.13
0.19
1.2
1.3
—
—
—
0
0
16
137
1.17
0.18
1.1
1.2
—
—
—
0
0
7
58
1.21
0.18
1.9
1.3
1.50
1.60
g/l
—
7
58
7
60
1.17
0.17
1.6
1.4
—
—
—
0
0
14
119
1.18
0.17
2.2
2.0
—
—
—
0
0
13
110
1.18
0.17
1.1
1.1
—
—
—
0
0
49
457
1.07
0.16
1.4
1.7
—
—
—
0
0
15
130
1.16
0.15
1.0
1.1
0.77
2.18
u/ml
—
6
51
6
78
0.77
0.15
1.2
1.1
25.62
34.31
mmol/l
—
6
70
13
112
1.16
0.14
1.5
1.5
34.33
33.25
%
—
8
72
19
171
1.11
0.12
1.8
2.2
—
—
—
0
0
6
55
1.09
0.09
1.2
1.3
124.83
147.06
nmol/l
—
6
55
18
165
1.09
0.08
4.3
2.8
—
—
—
0
0
39
372
1.05
0.07
1.1
1.1
—
—
—
0
0
26
276
0.94
0.07
1.2
1.3
416.08
520.42
mg/l
2.01
26
263
8
75
1.07
0.07
1.5
1.5
—
—
—
0
0
8
90
0.89
0.06
1.0
1.4
—
—
—
0
0
50
482
1.04
0.06
1.8
1.4
—
—
—
0
0
23
243
0.95
0.05
3.5
3.8
28.17
26.62
mg/l
0.08
15
154
10
110
0.91
0.05
1.0
1.4
—
—
—
0
0
12
130
0.92
0.04
1.1
1.1
0.27
2.73
u/ml
—
7
69
30
288
1.04
0.04
1.2
1.3
—
—
—
0
0
15
142
1.06
0.02
3.3
4.4
—
—
—
0
0
16
153
1.05
0.01
2.2
1.9
92.15
89.67
%
2.47
16
153
17
164
1.04
0.00
1.9
2.6
—
—
—
0
0
15
151
0.99
0.00
1.3
1.7
—
—
—
0
0
19
192
0.99
0.00
1.8
2.8
—
—
—
0
0
11
115
0.96
0.00
1.2
1.4
—
—
—
0
0
11
110
1.00
0.00
1.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
33.51
—
0
7
7
74
0.95
0.00
1.9
1.6
0.87
1.02
g/l
—
7
74
0
6
0.00
-0.00
0.0
1.7
—
2.25
—
0
6
7
73
0.96
-0.00
1.6
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.9
1.7
83.00
81.00
umol/l
—
7
73
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.05
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.4
1.3
—
—
—
0
0
7
73
0.96
-0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_KIDNEY and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_KIDNEY 1.198 [1.05, 1.36] 0.005
Birth year 0.993 [0.98, 1.0] 0.122

During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 3055 females with CD2_BENIGN_KIDNEY died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_KIDNEY 1.35 [1.17, 1.56] < 0.001
Birth year 0.99 [0.98, 1.0] 0.041

During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 1946 males with CD2_BENIGN_KIDNEY died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_KIDNEY.

N-year risk Females Males
1 0.095% 0.245%
5 0.589% 1.509%
10 1.686% 4.136%
15 3.282% 7.802%
20 5.995% 13.486%

Relationships between endpoints

Index endpoint: CD2_BENIGN_KIDNEY – Benign neoplasm: Kidney

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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