Benign neoplasm: Urinary organ, other/unspecified

CD2_BENIGN_URINARY_NOS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D30.7&, D30.9& Hospital discharge: ICD-9 — 223[8-9] Hospital discharge: ICD-8 — 223[8-9] Cause of death: ICD-10 — D30.7&, D30.9& Cause of death: ICD-9 — 223[8-9] Cause of death: ICD-8 — 223[8-9] 2 out of 7 registries used, show all original rules.	100
4. Check minimum number of events None	100
5. Include endpoints None	100
6. Filter based on genotype QC (FinnGen only)	100

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	CD2_BENIGN_URINARY_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D30[7\|9]
HD_ICD_9	223[8-9]
HD_ICD_8	223[8-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D30[7\|9]
COD_ICD_9	223[8-9]
COD_ICD_8	223[8-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Urinary organ, other/unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Urinary organ, other/unspecified

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	991	579	393
Only index persons	703	426	277
Unadjusted period prevalence (%)
Whole population	0.01	0.02	0.01
Only index persons	0.01	0.02	0.01
Median age at first event (years)
Whole population	58.75	57.59	60.12
Only index persons	53.30	53.31	53.29

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	100	63	37
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	50.12	46.55	56.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
90: Matched controls
899

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D30.9

ICD-10 Finland

Benign neoplasm: Urinary organ, unspecified

+∞

51.0

22388

ICD-8 Finland

Benign neoplasm of kidney and other urinary organs, Other specified sites

+∞

18.3

D30.7

ICD-10 Finland

Benign neoplasm: Other urinary organs

+∞

10.6

D30.0

ICD-10 Finland

Benign neoplasm: Kidney

30.9

8.7

22399

ICD-8 Finland

Benign neoplasm of kidney and other urinary organs, Unspecified site

+∞

8.5

UKC02

NOMESCO Finland

Cystoscopy

3.8

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3000850) Epithelial cells [#/volume] in Urine

153

2.15

2.75

1.9

2.7

7.2

5.4

e6/l

0.25

141

(3030467) Casts [#/volume] in Urine by Automated count

186

2.06

2.67

2.7

3.0

0.2

0.5

e6/l

0.78

145

(36304419) Bacteria [Presence] in Urine

185

1.98

2.38

2.7

3.0

—

(3032080) INR in Blood by Coagulation assay

298

1.85

2.31

12.3

7.3

1.1

1.3

inr

0.59

(3018095) Leukocytes [#/volume] in Urine

251

1.83

2.13

3.1

3.5

141.1

54.0

e6/l

0.43

185

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.89

1.99

14.3

5.0

23.9

25.5

mmol/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

101

2.09

1.97

2.7

2.5

2.8

1.0

e6/l

0.52

(3002582) Erythrocytes [#/volume] in Urine

213

1.82

1.97

2.7

3.0

26.0

311.1

e6/l

0.50

173

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

180

1.86

1.96

2.2

2.0

2.5

3.0

mg/l

0.72

159

(3001122) Ferritin [Mass/volume] in Serum or Plasma

302

1.74

1.93

3.6

2.6

116.5

107.1

ug/l

0.13

282

(40761536) Microorganisms panel - Urine sediment

2.27

1.86

5.7

3.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.51

1.85

1.4

—

(1616796) Gas panel - Central venous blood

3.99

1.73

1.4

—

(3037522) Nuclear Ab [Titer] in Serum

2.00

1.64

1.4

1.5

664.0

577.6

titre

—

(3027315) Oxygen [Partial pressure] in Blood

3.70

1.63

2.4

1.9

8.8

9.1

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

3.70

1.63

2.4

1.9

5.0

4.8

kpa

—

(36660697) Celiac disease serology panel - Serum

2.30

1.57

1.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.95

1.55

2.8

2.6

117.3

2.7

e6/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

513

1.62

1.48

6.1

4.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.17

1.39

1.5

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.98

1.38

3.9

3.5

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.59

1.32

1.5

2.2

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

327

1.55

1.31

3.8

3.7

35.5

35.3

g/l

0.10

308

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

245

1.59

1.30

3.7

3.0

—

(3049717) Cytology report of Urine Cyto stain

2.49

1.26

2.7

2.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

303

1.53

1.22

2.4

1.9

92.8

98.1

pmol/l

0.32

140

(3019832) Treponema pallidum Ab [Presence] in Serum

2.03

1.11

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.45

1.10

1.6

2.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.01

0.99

1.9

2.1

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.01

0.99

1.4

1.9

—

(3015736) pH of Urine

290

1.44

0.92

5.3

3.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

129

1.58

0.92

2.2

1.4

1.9

2.4

g/l

0.45

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.98

0.91

1.3

1.6

—

(40761535) Cells panel - Urine sediment

1.78

0.86

6.1

3.0

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

159

1.49

0.81

1.5

1.2

0.5

2.2

u/ml

—

(42870588) Differential panel, method unspecified - Blood

250

1.41

0.80

5.6

4.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

317

1.38

0.77

3.8

3.7

36.5

31.7

ng/l

0.12

224

(3007853) Bacteria identified in Skin by Aerobe culture

1.63

0.76

2.5

1.4

—

(3022145) Colonoscopy Study observation

101

1.57

0.75

1.3

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

465

1.35

0.73

6.0

4.0

7.3

6.7

mmol/l

1.13

437

(3004588) Protein electrophoresis panel - Serum or Plasma

1.81

0.73

3.1

1.4

—

(3019225) pH of Specimen

1.67

0.72

15.2

5.0

—

(3012516) Albumin [Mass/volume] in Urine

219

0.68

0.67

3.9

3.1

13.7

26.9

mg/l

—

141

(3012095) Magnesium [Moles/volume] in Serum or Plasma

131

1.46

0.65

3.2

2.8

0.8

mmol/l

0.04

125

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

344

1.33

0.64

10.3

4.8

1.2

mmol/l

0.09

312

(3000991) Gas panel - Venous blood

1.65

0.63

17.6

5.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

150

1.42

0.62

2.9

1.6

1217.5

1214.1

nmol/l

0.01

117

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.63

0.61

1.2

1.8

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.48

0.58

7.1

3.6

1.1

1.0

mmol/l

0.26

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.71

0.58

1.2

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.47

0.54

6.2

3.9

1.2

mmol/l

—

(3044889) 12 lead EKG panel

531

0.78

0.54

4.5

3.8

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

560

1.28

0.53

6.0

4.3

14.8

14.9

pmol/l

0.09

506

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.45

0.53

1.7

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.53

0.52

20.0

6.4

95.7

93.1

—

(3000494) Fungus identified in Specimen by Culture

1.49

0.52

1.2

1.4

—

(3035350) Ketones [Presence] in Urine by Test strip

363

1.27

0.51

5.7

3.8

0.0

estimate

0.00

(3021601) Nitrite [Presence] in Urine by Test strip

365

1.26

0.48

7.1

5.2

0.0

estimate

0.00

(3013707) Erythrocyte sedimentation rate by Westergren method

566

1.25

0.46

5.7

4.3

12.7

12.6

mm/h

0.04

519

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.46

0.45

1.5

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

368

1.24

0.44

13.3

6.4

1.2

mmol/l

0.28

316

(3009261) Glucose [Presence] in Urine by Test strip

369

1.24

0.43

5.6

3.8

0.0

estimate

0.00

(3022313) Gas panel - Capillary blood

1.54

0.42

8.6

3.4

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.41

0.0

2.4

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.41

0.0

1.3

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.41

0.0

1.5

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

1.9

—

4.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

1.9

—

107.5

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

1.9

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.49

0.41

1.0

1.8

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.40

0.0

2.5

—

17.5

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.45

0.40

7.6

5.4

—

(3029937) Albumin [Presence] in Urine by Test strip

210

1.25

0.37

7.0

3.8

0.0

estimate

0.00

(3026008) Bacteria identified in Urine by Culture

249

1.23

0.36

5.2

3.0

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

608

1.20

0.32

9.2

6.9

82.9

77.1

u/l

0.31

568

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.34

0.31

1.9

2.3

—

(3013512) EKG study

243

1.21

0.31

4.3

3.4

—

(3001604) Monocytes [#/volume] in Blood

379

1.19

0.31

5.1

5.2

0.5

0.6

e9/l

0.46

332

(3013115) Eosinophils [#/volume] in Blood

389

1.18

0.31

5.1

5.6

0.2

e9/l

0.02

345

(3019198) Lymphocytes [#/volume] in Blood

389

1.18

0.31

5.1

5.3

1.8

2.0

e9/l

0.33

348

(3021960) Folate [Moles/volume] in Serum or Plasma

177

1.24

0.31

1.7

1.6

22.3

20.7

nmol/l

0.11

147

(3006315) Basophils [#/volume] in Blood

380

1.18

0.30

5.1

5.2

0.0

e9/l

0.60

335

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

683

1.19

0.29

6.8

5.0

1.7

1.9

mu/l

0.61

611

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

706

0.85

0.28

4.3

4.1

1.4

1.3

mmol/l

1.04

636

(3021589) Normoblasts [#/volume] in Blood

333

1.18

0.28

10.9

9.7

0.0

e9/l

0.50

274

(3002256) Pathology report gross observation

1.31

0.27

1.1

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

218

1.20

0.27

5.1

3.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

296

1.17

0.26

6.5

3.9

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

732

0.85

0.24

4.8

4.7

1.4

1.5

mmol/l

1.35

668

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

749

1.19

0.24

18.8

13.6

23.5

21.3

mg/l

0.24

612

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.27

0.24

1.8

1.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

648

1.15

0.22

14.8

14.3

39.3

39.9

0.19

454

(3025941) Bacteria identified in Stool by Culture

1.23

0.22

1.2

1.3

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.23

0.22

23.6

6.1

0.5

0.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.20

0.22

23.6

6.0

0.9

1.7

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

2.2

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

238

0.85

0.21

5.8

3.8

7.3

5.3

mg/mmol

0.16

145

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.21

0.0

1.2

—

50.7

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

175

1.18

0.20

2.4

2.1

—

(1761868) Lipid panel - Serum or Plasma

253

1.15

0.19

3.4

3.1

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

737

0.87

0.19

4.7

4.8

4.6

mmol/l

0.54

678

(40768797) Stomach Pathology biopsy report

100

1.23

0.19

1.2

1.3

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

421

1.13

0.19

6.4

5.6

10.3

10.6

umol/l

0.08

400

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.24

0.19

2.0

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

452

1.12

0.18

8.1

9.4

3.7

4.1

e9/l

0.54

400

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

704

1.14

0.18

16.5

12.9

78.5

79.0

ml/min/173m2

0.06

574

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

120

1.19

0.17

1.6

1.3

—

(3012544) pH of Venous blood

1.21

0.17

3.1

2.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

102

1.20

0.16

1.9

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

181

0.86

0.15

3.6

4.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.14

0.15

1.3

1.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

131

1.17

0.15

1.2

1.3

61.5

7.8

u/ml

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.20

0.13

13.4

5.8

5.2

kpa

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

359

1.09

0.12

3.7

3.8

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

792

1.12

0.11

21.0

16.2

83.0

75.0

umol/l

0.83

792

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

702

1.09

0.10

7.3

6.1

40.7

mmol/mol

0.02

650

(3019150) Specific gravity of Urine by Refractometry

165

0.89

0.09

8.4

4.0

1.0

kg/l

—

(4010399)

1.08

0.09

1.8

1.3

—

(3002032) Base excess in Venous blood by calculation

1.10

0.08

3.3

2.4

-1.2

3.0

mmol/l

—

(4035726)

1.08

0.08

1.6

1.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

755

0.92

0.08

5.3

5.2

2.9

2.7

mmol/l

0.69

686

(3011397) Hemoglobin [Presence] in Urine by Test strip

157

1.10

0.07

6.5

3.7

—

(40768804) Tissue Pathology biopsy report

296

1.07

0.07

2.2

2.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

100

0.89

0.06

6.4

7.7

—

(40761511) CBC panel - Blood by Automated count

773

0.93

0.06

20.7

13.2

—

(3023368) Bacteria identified in Blood by Culture

218

1.07

0.06

4.6

3.9

—

(3042936) Bacteria identified in Isolate by Culture

110

1.10

0.05

2.4

1.8

—

(3018418) pH of Serum or Plasma

231

0.94

0.05

4.4

3.3

7.4

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

123

1.07

0.02

1.8

1.7

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

497

0.97

0.01

4.1

2.9

47.1

48.1

u/l

0.03

463

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

144

1.05

0.00

5.6

4.0

20.5

21.0

—

(3003694) ABO and Rh group [Type] in Blood

188

1.01

0.00

1.7

1.5

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

725

1.03

0.00

5.8

4.8

6.1

6.0

mmol/l

0.60

667

(3044640) Blood type and Crossmatch panel - Blood

245

1.03

0.00

2.4

2.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

434

0.98

0.00

2.8

2.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.96

0.00

1.4

1.2

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

0.0

6.2

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

23.2

—

1675.2

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.98

0.00

3.2

1.6

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

1.9

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.1

—

(40758558) Short blood count panel - Blood

200

1.00

0.00

2.5

6.7

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

0.3

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.5

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

36.6

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.0

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.0

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

1.8

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.1

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.8

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.2

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.00

0.00

1.4

1.6

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

14.5

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(4146454)

0.00

0.0

3.8

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(4062490)

0.00

0.0

1.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

15.6

—

875.4

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.0

—

4.9

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.6

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.3

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.5

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

0.8

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.0

—

147.3

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.4

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.8

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_URINARY_NOS and mortality.

Females

Parameter	HR [95% CI]	p-value
CD2_BENIGN_URINARY_NOS	2.076 [1.53, 2.81]	< 0.001
Birth year	0.992 [0.98, 1.0]	0.075

During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 274 females with CD2_BENIGN_URINARY_NOS died.

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_URINARY_NOS	1.753 [1.16, 2.64]	0.007
Birth year	0.989 [0.98, 1.0]	0.017

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 186 males with CD2_BENIGN_URINARY_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_URINARY_NOS.

N-year risk	Females	Males
1	0.158%	0.392%
5	1.142%	2.311%
10	2.997%	5.351%
15	5.58%	10.066%
20	9.505%	17.181%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_URINARY_NOS – Benign neoplasm: Urinary organ, other/unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Urinary organ, other/unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints