Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

CD2_BENIGN_EAR_NASAL_SINUS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D14.0&
  • Hospital discharge: ICD-9 2120
  • Hospital discharge: ICD-8 2120
  • Cause of death: ICD-10 D14.0&
  • Cause of death: ICD-9 2120
  • Cause of death: ICD-8 2120

2 out of 7 registries used, show all original rules.

1545

4. Check minimum number of events

None

1545

5. Include endpoints

None

1545

6. Filter based on genotype QC (FinnGen only)

1489

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D14
Name in latin
Neoplasma benignum auris mediae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9658 4526 5061
Only index persons 8673 4172 4501
Unadjusted period prevalence (%)
Whole population 0.14 0.13 0.14
Only index persons 0.16 0.15 0.17
Median age at first event (years)
Whole population 53.85 54.43 53.29
Only index persons 52.85 53.43 52.31

-FinnGen-

Key figures

All Female Male
Number of individuals 1489 702 787
Unadjusted period prevalence (%) 0.31 0.25 0.36
Median age at first event (years) 56.81 55.12 58.31

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1545
Matched controls
15450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
4503599627370496.0
307.7
1375
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
11.8
307.7
456
530
DHA10
NOMESCO Finland
Biopsy of cavity of nose
89.4
307.7
273
37
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
130.2
281.5
142
12
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
10.9
265.1
316
356
DHB10
NOMESCO Finland
Excision of lesion of internal nose
342.9
260.7
257
9
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
11.5
213.9
238
241
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
14.6
208.6
196
152
UDM02
NOMESCO Finland
Sinoscopy
15.6
198.4
179
129
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
87.1
185.6
98
12
J33.0
ICD-10 Finland
Polyp of nasal cavity
9.8
150.4
184
210
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
5.4
121.2
268
574
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
19.5
108.0
85
46
DPA30
NOMESCO Finland
Sphenotomy
23.1
102.6
75
34
J33.8
ICD-10 Finland
Other polyp of sinus
9.3
99.9
124
143
DHB40
NOMESCO Finland
Conchotomy
57.0
97.2
55
10
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.3
96.9
288
778
2120A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Nasal cavities, middle ear and accessory sinuses
+∞
91.6
87
*
DHB20
NOMESCO Finland
Polypectomy of internal nose
10.6
90.2
101
101
DMB10
NOMESCO Finland
Radical maxillary antrotomy
23.0
84.8
62
28
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
20.4
79.4
61
31
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
17.1
76.6
64
39
J33.9
ICD-10 Finland
Nasal polyp, unspecified
11.7
75.7
79
71
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.0
73.9
137
246
R01AD08
ATC
fluticasone; nasal
2.7
70.1
575
2814
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
7.0
63.4
99
149
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
11.9
60.5
62
54
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
600.3
59.1
58
*
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
150.5
55.2
58
*
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
68.0
51.5
59
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
49.9
509
2677
ZXC10
NOMESCO Finland
Use of laser
6.6
49.9
82
130
R01AD09
ATC
mometasone; nasal
2.2
47.5
774
4899
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
44.0
679
4173
DHB00
NOMESCO Finland
Excision of lesion of external nose
9.6
43.8
52
56
J31.0
ICD-10 Finland
Chronic rhinitis
3.1
42.2
189
655
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
10.3
41.7
47
47
R04.0
ICD-10 Finland
Epistaxis
3.1
40.3
186
655
DMB30
NOMESCO Finland
Transmaxillary excision of lesion of maxillary antrum
210.4
40.0
41
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.6
39.9
143
431
21202
ICD-8 Finland
Benign neoplasm of respiratory system, Sinus maxillaris
+∞
39.8
38
*
ZXE00
NOMESCO Finland
One hour or less
2.0
39.5
673
4242
DJW00
NOMESCO Finland
Removal of local lesion of nasal septum
88.5
39.0
43
5
21200
ICD-8 Finland
Benign neoplasm of respiratory system, Cavi nasi
+∞
38.7
37
*
DMB35
NOMESCO Finland
Endoscopic excision of neoplasm or another lesion from maxillary sinus
355.0
35.1
35
*
DKW40
NOMESCO Finland
Ligature of artery of internal nose
184.2
34.9
36
*
ZXC95
NOMESCO Finland
Use of surgical navigator
8.1
34.2
46
58
4256
FHL
Nasal or sinus tumor removal
334.0
33.0
33
*
Z2221
NOMESCO Finland
Medical doctor
2.0
32.4
470
2755
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
31.5
614
3971
ZXD20
NOMESCO Finland
Day surgery
2.4
30.4
244
1131
J34.1
ICD-10 Finland
Cyst and mucocele of nose and nasal sinus
6.2
30.3
52
86
R01AD12
ATC
fluticasone furoate; nasal
1.9
29.9
493
3008
B977, D140,
ICD-10 Finland
+∞
28.2
27
*
H02AB06
ATC
prednisolone; systemic
1.8
28.1
771
5490
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
27.4
818
5955
WX402
NOMESCO Finland
General anaesthesia
2.0
27.2
356
1995
ZXA05
NOMESCO Finland
Left side
1.9
26.5
425
2551
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
26.3
372
2140
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
26.1
342
1914
DNB40
NOMESCO Finland
Sublabial rhinotomy
+∞
26.1
25
*
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
40.8
25.9
32
8
DJA10
NOMESCO Finland
Biopsy of septum of nose
127.0
23.6
25
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.6
23.5
80
232
DHB50
NOMESCO Finland
Turbinoplasty
4.0
23.5
67
172
UDQ22
NOMESCO Finland
Microlaryngoscopy
7.2
22.1
33
47
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
21.8
1071
8717
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
44.0
21.4
26
6
J32.1
ICD-10 Finland
Chronic frontal sinusitis
8.4
21.4
28
34
ZXA00
NOMESCO Finland
Right side
1.8
21.2
436
2798
WX002
NOMESCO Finland
Sedation and analgesia
1.9
20.5
328
1947
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
20.4
20.4
30
15
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
6.5
20.1
33
52
J32.4
ICD-10 Finland
Chronic pansinusitis
5.1
19.8
42
85
DPW99
NOMESCO Finland
Other operation on frontal or sphenoidal sinus
28.2
18.7
25
9
DPB00
NOMESCO Finland
Partial excision of frontal sinus
70.8
18.7
21
*
ZXA10
NOMESCO Finland
Bilateral
1.8
18.4
298
1770
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
18.1
235
1297
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
14.5
18.1
30
21
R08
ICPC
Nose symptom/complaint other
3.3
17.9
69
217
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
96.2
17.6
19
*
J01DB01
ATC
cefalexin; oral
1.8
17.2
1244
10819
R01AD58
ATC
fluticasone, combinations; nasal
1.7
17.1
345
2182
DKW30
NOMESCO Finland
Cauterisation of artery of internal nose
6.9
17.0
26
38
D10.6
ICD-10 Finland
Benign neoplasm: Nasopharynx
25.9
16.9
23
9
J34.2
ICD-10 Finland
Deviated nasal septum
2.5
16.7
108
450
DMB40
NOMESCO Finland
Excision of lesion of maxillary antrum trough lateral rhinotomy
+∞
16.7
16
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.9
16.7
81
292
UDC00
NOMESCO Finland
Ear microscopy
2.3
16.0
131
607
R06AE07
ATC
cetirizine; oral
1.6
15.8
619
4616
D38.50
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of maxillary sinus
33.7
15.7
20
6
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
15.4
65
216
4226
FHL
Posterior radical surgery and possible etmoidectomy
6.0
15.3
27
46
8070/3-C30.0
ICD-O-3
Squamous cell carcinoma, NOS, of nasal cavity
45.5
15.1
18
*
4222
FHL
Endonasal etmoidectomy
6.6
14.9
24
37
R01AD01
ATC
beclometasone; nasal
1.8
14.9
236
1386
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
14.5
700
5431
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
5.9
14.5
26
45
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
14.5
664
5097
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
14.4
511
3707
J01AA02
ATC
doxycycline; systemic
1.6
14.3
1161
10079
DPA20
NOMESCO Finland
Trephine of frontal sinus
22.5
14.2
20
9
R51.81
ICD-10 Finland
Facial pain NOS
3.6
14.1
47
135
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.0
13.8
149
769
J01.1
ICD-10 Finland
Acute frontal sinusitis
4.2
13.7
36
87
DPC35
NOMESCO Finland
Extensive endoscopic excision of lesion or neoplasm extending to more than one paranasal sinus
75.8
13.6
15
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
11.0
13.5
25
23
J01CA04
ATC
amoxicillin; systemic
1.6
13.4
1197
10521
J01FA10
ATC
azithromycin; systemic
1.5
13.3
797
6432
DMA10
NOMESCO Finland
Exploration of maxillary antrum
40.4
13.2
16
*
G50.1
ICD-10 Finland
Atypical facial pain
3.9
13.1
38
99
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
12.8
245
1518
J33
ICD-10 Finland
Nasal polyp
5.8
12.7
23
40
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
70.5
12.6
14
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
12.5
1331
12080
B07.9
ICD-10 Finland
Verruca simplex
2.8
12.4
61
222
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.5
12.1
77
319
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
11.9
377
2645
D38.58
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other respiratory organ
47.0
11.9
14
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
11.9
604
4681
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
11.8
608
4725
R4110
NOMESCO Finland
Physiotherapy
1.5
11.8
403
2877
A07AA02
ATC
nystatin; oral
2.2
11.6
94
434
Z3231
NOMESCO Finland
Registered nurse
1.5
11.5
395
2818
DQA10
NOMESCO Finland
Biopsy of larynx
5.7
11.5
21
37
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
4.4
11.5
28
64
A02BC02
ATC
pantoprazole; systemic
1.5
11.3
995
8529
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
11.2
72
300
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.4
11.1
40
121
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.8
10.9
33
89
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
10.5
499
3794
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
10.5
267
1774
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
10.5
92
439
DCB00
NOMESCO Finland
Excision of lesion of middle ear
110.8
10.4
11
*
D14.4
ICD-10 Finland
Benign neoplasm: Respiratory system, unspecified
110.8
10.4
11
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.8
10.4
52
191
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
10.4
322
2242
WF002
NOMESCO Finland
Radical radiotherapy
2.2
10.3
89
422
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
10.3
426
3152
N02AX02
ATC
tramadol; systemic, rectal
1.4
10.3
629
5012
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.7
10.2
56
216
DKW99
NOMESCO Finland
Other procedures for control of epistaxis
13.2
10.2
17
13
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
10.1
258
1716
H65.3
ICD-10 Finland
Chronic mucoid otitis media
3.4
10.0
35
104
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
4.8
10.0
22
46
UDQ02
NOMESCO Finland
Direct laryngoscopy
4.7
10.0
23
50
R03AC02
ATC
salbutamol; inhalant
1.4
9.8
764
6336
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
9.8
79
365
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.6
9.7
56
222
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
9.6
1315
12082
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
9.5
526
4098
R06AX22
ATC
ebastine; oral
1.6
9.5
233
1533
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
9.5
119
647
DPB10
NOMESCO Finland
Partial excision of sphenoidal sinus
100.6
9.4
10
*
J01DA01
ATC
[U] cefalexin
1.4
9.4
882
7524
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
9.4
271
1852
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
9.4
9
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
9.3
76
352
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
9.3
246
1649
J45
ICD-10 Finland
Asthma
1.8
9.1
137
788
R01AD05
ATC
budesonide; nasal
1.9
9.1
112
606
R03DC03
ATC
montelukast; oral
1.6
9.0
223
1470
A02BC01
ATC
omeprazole; systemic
1.5
9.0
379
2802
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
4.2
8.9
23
55
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
8.9
204
1320
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
8.9
360
2641
A03
ICPC
Fever
1.6
8.9
210
1369
M31.3
ICD-10 Finland
Wegener granulomatosis
12.6
8.9
15
12
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
8.9
370
2730
N03
ICPC
Pain face
4.9
8.8
19
39
J01DC02
ATC
cefuroxime; systemic
2.2
8.8
77
367
UJF32
NOMESCO Finland
Coloscopy
1.5
8.8
370
2733
A02BC03
ATC
lansoprazole; oral
1.4
8.8
412
3108
UJH02
NOMESCO Finland
Anoscopy
2.3
8.6
66
298
S29
ICPC
Skin symptom/complaint other
1.5
8.6
256
1762
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.5
318
2294
1210
FHL
Anthroscopy
12.8
8.4
14
11
J01FA09
ATC
clarithromycin; systemic
1.4
8.4
418
3185
4239
FHL
Other measure in this category
7.9
8.4
18
23
A02BC05
ATC
esomeprazole; systemic
1.4
8.4
564
4526
DPA35
NOMESCO Finland
Endoscopic excision of lesion or neoplasm from frontal sinus
+∞
8.3
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.4
8.3
56
239
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
8.2
122
701
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
8.1
65
299
Z3226
NOMESCO Finland
Physiotherapist
1.5
8.1
253
1755
ZZC00
NOMESCO Finland
Graft of fascia
33.5
8.1
10
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.0
8.1
92
485
Z01.2
ICD-10 Finland
Dental examination
1.4
8.0
590
4792
J01
ICD-10 Finland
Acute sinusitis
2.1
8.0
73
355
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
7.3
8.0
18
25
H02AB04
ATC
methylprednisolone; systemic
1.6
8.0
200
1322
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
7.9
112
634
E0000UV, ,
ATC
1.4
7.9
548
4409
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
7.9
105
583
DC1AD
NOMESCO Finland
Temporalbone CT
4.1
7.8
21
52
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
10.9
7.8
14
13
J01FF01
ATC
clindamycin; systemic
1.4
7.8
379
2869
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.8
7.7
113
646
R21
ICPC
Throat symptom/complaint
1.5
7.7
235
1624
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
7.6
745
6314
KMAK, ,
NOMESCO Finland
1.3
7.5
678
5669
J01FA06
ATC
roxithromycin; oral
1.4
7.5
543
4390
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.3
7.5
19
45
J38.1
ICD-10 Finland
Polyp of vocal cord and larynx
4.4
7.4
18
41
DJB10
NOMESCO Finland
Excision of septum of nose
80.5
7.4
8
*
D35.59
ICD-10 Finland
Other paragangliom
80.5
7.4
8
*
B977, D141,
ICD-10 Finland
80.5
7.4
8
*
C72.2
ICD-10 Finland
Malignant neoplasm: Olfactory nerve
80.5
7.4
8
*
D07AC01
ATC
betamethasone; topical
1.4
7.4
488
3884
D01
ICPC
Abdominal pain/cramps general
1.7
7.4
146
908
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.4
975
8622
R03BA02
ATC
budesonide; inhalant
1.5
7.4
241
1688
SFA10
NOMESCO Finland
One-surface restoration
1.3
7.3
730
6189
21208
ICD-8 Finland
Benign neoplasm of respiratory system, Nasi, loco multiplici
+∞
7.3
7
*
21209
ICD-8 Finland
Benign neoplasm of respiratory system, Nasi, NUD
+∞
7.3
7
*
DPA40
NOMESCO Finland
Excision of lesion or neoplasm from sphenoid sinus
+∞
7.3
7
*
9522/3-C30.0
ICD-O-3
Olfactory neuroblastoma of nasal cavity
+∞
7.3
7
*
EEB10
NOMESCO Finland
Maxillectomy
+∞
7.3
7
*
H02AB07
ATC
prednisone; oral
1.6
7.3
188
1250
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.2
153
970
R51.80
ICD-10 Finland
Headache
1.6
7.2
196
1320
R05
ICD-10 Finland
Cough
1.5
7.2
278
2015
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.6
7.2
23
65
G44.2
ICD-10 Finland
Tension-type headache
1.6
7.1
171
1118
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.1
304
2244
J32.8
ICD-10 Finland
Other chronic sinusitis
8.0
7.1
15
19
R06AX27
ATC
desloratadine; oral
1.4
7.0
349
2645
J01MA12
ATC
levofloxacin; systemic
1.5
7.0
261
1876
ZXD05
NOMESCO Finland
Urgent procedure
1.4
7.0
410
3199
SFA20
NOMESCO Finland
Two-surface restoration
1.3
7.0
775
6659
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
6.4
6.9
17
27
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.6
6.9
22
62
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
3.6
6.9
22
62
N05CF01
ATC
zopiclone; oral
1.4
6.8
439
3473
SAA04
NOMESCO Finland
Special examination of mouth
2.0
6.8
76
398
J32.3
ICD-10 Finland
Chronic sphenoidal sinusitis
9.4
6.8
13
14
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
6.1
6.8
17
28
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.8
390
3030
M79.1
ICD-10 Finland
Myalgia
1.6
6.8
181
1213
ZXC99
NOMESCO Finland
Other special technic in surgery
16.8
6.7
10
6
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.7
144
915
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.7
622
5196
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.5
6.7
41
168
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
6.7
153
989
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
6.5
6.6
16
25
J01DA06
ATC
[U] cefuroxime
1.5
6.6
188
1278
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.5
6.6
22
64
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.6
172
1147
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.0
6.5
27
90
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.5
774
6688
R05
ICPC
Cough
1.4
6.5
305
2288
8720/3-C30.0
ICD-O-3
Malignant melanoma, NOS, of nasal cavity
70.1
6.4
7
*
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.1
6.4
60
295
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.3
6.4
47
210
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
6.4
241
1736
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
6.4
872
7673
B01AB05
ATC
enoxaparin; parenteral
1.4
6.3
424
3373
DM1BG
NOMESCO Finland
Paranasal sinuses and face area standard MRI examination with high intensity magnet
+∞
6.3
6
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.2
547
4521
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.2
373
2911
AA1AD
NOMESCO Finland
CT of head and brain
1.4
6.2
371
2893
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
2.6
6.2
35
138
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
6.1
95
553
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
6.1
264
1947
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.5
6.1
37
151
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
2.9
6.1
28
99
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.1
590
4941
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
6.1
87
495
4252
FHL
Resection, coagulation or cryo on the cortex and nasal mucosa
12.6
6.1
10
8
S18
ICPC
Laceration/cut
1.3
6.0
624
5271
R06.0
ICD-10 Finland
Dyspnoea
1.4
6.0
367
2870
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
10.1
6.0
11
11
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
6.0
350
2717

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
841
4933
2.55
69.99
2.8
2.1
—
—
—
0
0
284
1501
2.09
25.30
2.0
1.7
—
—
—
0
0
224
1115
2.18
23.17
1.5
1.4
—
—
—
0
0
322
1875
1.91
21.46
2.3
2.1
—
—
—
0
0
515
3505
1.70
20.09
3.3
3.1
0.37
0.48
e6/l
0.71
392
2703
500
3400
1.70
19.44
3.2
3.1
—
—
—
0
0
279
1613
1.89
18.78
1.3
1.3
—
—
—
0
0
725
5468
1.61
18.47
5.0
5.1
35.39
35.39
g/l
0.01
675
5083
529
3725
1.64
17.60
4.4
4.0
7.40
7.40
ph
0.01
104
738
542
3849
1.63
17.38
3.4
3.3
88.32
87.12
e6/l
0.01
405
3014
606
4430
1.61
17.21
4.1
3.7
65.21
118.71
e6/l
1.07
429
3215
741
5709
1.57
16.63
6.8
6.2
1.21
1.21
mmol/l
0.99
698
5208
1063
8953
1.60
15.77
4.3
3.9
—
—
—
0
0
1137
9751
1.63
15.46
8.6
7.7
79.25
79.05
u/l
0.05
1073
9189
825
6668
1.51
13.87
6.3
6.4
12.03
11.61
umol/l
0.25
784
6340
1079
9268
1.54
13.32
4.5
4.1
13.03
12.35
mm/h
0.69
1006
8547
780
6273
1.49
13.16
7.6
7.1
1.21
1.21
mmol/l
0.63
652
5319
234
1432
1.75
12.74
2.6
2.8
5.76
8.58
umol/l
3.93
204
1261
444
3197
1.55
12.59
4.6
4.0
89.75
88.82
%
0.34
434
3122
321
2147
1.62
12.48
3.1
2.7
0.73
1.06
e6/l
2.66
192
1245
1210
10732
1.59
12.32
21.6
17.5
15.09
15.01
%
0.17
1194
10527
438
3164
1.54
12.17
7.7
6.6
—
—
—
0
0
340
2338
1.58
11.70
2.9
3.1
2.45
2.45
mmol/l
0.19
289
2061
873
7276
1.46
11.69
9.9
9.1
4.29
4.16
e9/l
0.81
751
6367
299
2027
1.59
10.85
3.3
2.9
2.05
2.17
e6/l
0.09
167
1132
377
2693
1.53
10.85
2.5
2.6
3.98
5.35
e6/l
1.96
327
2439
762
6248
1.43
10.78
6.8
5.8
0.61
0.59
e9/l
1.38
641
5407
761
6258
1.43
10.48
6.9
5.8
0.04
0.04
e9/l
0.02
642
5418
953
8162
1.44
10.47
4.9
4.4
3301.88
1702.95
e6/l
—
8
118
723
5916
1.42
10.11
2.5
2.6
—
—
—
0
0
234
1522
1.63
10.02
1.7
1.4
—
—
—
0
0
685
5564
1.42
9.93
11.0
9.7
0.00
0.00
e9/l
0.46
546
4565
1350
12466
1.66
9.80
18.8
14.8
23.42
25.06
mg/l
1.12
1132
9925
719
5906
1.41
9.69
7.2
6.4
—
—
—
0
0
777
6471
1.40
9.65
7.1
6.1
0.20
0.19
e9/l
1.19
671
5690
187
1162
1.69
9.54
2.8
2.4
33.64
80.37
u/l
0.59
157
989
770
6412
1.40
9.52
6.9
5.9
1.88
1.93
e9/l
0.27
664
5674
712
5861
1.40
9.37
7.1
6.0
3.05
2.86
%
1.22
663
5476
714
5889
1.39
9.24
7.3
6.3
8.73
8.72
%
0.03
667
5503
540
4255
1.41
9.09
3.3
3.4
2.35
2.35
mmol/l
0.09
491
3739
355
2594
1.48
8.94
3.2
2.9
548.79
546.19
mosm/kgh2o
0.08
296
2238
725
6031
1.38
8.74
7.1
6.1
26.89
27.39
%
0.58
676
5653
871
7485
1.38
8.48
5.7
5.0
6.78
6.76
mmol/l
0.08
823
7038
687
5697
1.37
8.30
7.1
6.0
0.68
0.68
%
0.12
639
5314
292
2080
1.50
8.29
4.2
3.4
0.82
0.82
mmol/l
0.00
272
1960
1381
12938
1.63
8.10
21.4
17.2
139.57
139.67
mmol/l
0.75
1364
12600
1384
12975
1.64
8.07
21.5
17.3
3.96
3.98
mmol/l
1.58
1364
12618
721
6044
1.36
8.05
17.8
15.8
1.29
1.29
inr
0.03
219
1794
635
5220
1.37
8.02
2.1
2.0
95.08
94.40
pmol/l
0.13
324
2744
99
539
1.89
7.88
2.7
1.4
10.92
10.63
u/ml
—
9
14
49
202
2.47
7.87
2.6
2.7
—
—
—
0
0
459
3588
1.40
7.86
4.9
4.4
—
—
—
0
0
1049
9345
1.38
7.85
4.3
3.9
14.80
14.85
pmol/l
0.26
967
8455
372
2815
1.42
7.64
4.3
3.6
—
—
—
0
0
972
8572
1.36
7.63
4.8
4.3
—
—
—
0
0
706
5937
1.35
7.56
7.1
5.9
57.37
57.57
%
0.17
657
5561
173
1129
1.60
7.25
3.1
2.2
367.89
369.68
nmol/l
0.04
167
1030
136
840
1.68
7.09
1.3
1.4
—
—
—
0
0
1232
11346
1.42
7.07
5.2
4.6
1.89
2.15
mu/l
1.07
1141
10335
500
4044
1.35
6.72
2.5
2.6
59.56
79.41
u/l
0.50
468
3748
149
968
1.60
6.37
2.7
2.8
10.34
10.64
g/l
0.39
135
883
492
4008
1.33
6.21
2.4
2.5
—
—
—
0
0
599
5027
1.31
6.10
2.4
2.2
77.02
77.09
nmol/l
0.02
539
4481
478
3886
1.33
6.09
2.0
2.2
185.63
225.58
u/l
0.73
452
3657
162
1088
1.55
6.00
10.3
8.6
—
—
—
0
0
1403
13352
1.55
5.85
12.3
10.6
26.23
26.93
u/l
0.95
1364
12876
243
1782
1.43
5.82
1.2
1.2
—
—
—
0
0
209
1497
1.46
5.68
8.7
8.2
5.08
5.09
kpa
0.08
200
1430
1370
12987
1.48
5.67
16.2
14.1
—
—
—
0
0
209
1498
1.46
5.66
8.7
8.2
13.01
12.09
kpa
1.24
199
1433
264
1997
1.39
5.28
2.5
2.1
30.22
29.91
s
0.33
257
1933
207
1503
1.44
5.22
8.8
8.2
1.28
1.15
mmol/l
0.21
169
1189
250
1877
1.40
5.22
1.7
1.7
—
—
—
0
0
609
5205
1.28
5.16
3.3
2.8
150.07
139.78
ug/l
0.22
570
4773
1443
13885
1.59
4.97
27.0
21.6
247.53
247.49
e9/l
0.01
1421
13523
1443
13888
1.59
4.92
26.9
21.5
90.98
91.16
fl
0.90
1435
13667
1443
13891
1.59
4.88
27.0
21.6
4.51
4.50
e12/l
0.18
1416
13485
64
356
1.83
4.87
1.2
1.2
—
—
—
0
0
1443
13894
1.58
4.84
27.1
21.7
135.33
135.87
g/l
0.68
1435
13671
154
1073
1.48
4.82
2.9
2.9
211.74
200.89
ng/l
0.11
142
977
393
3198
1.31
4.80
2.5
2.2
3.07
3.02
mg/l
0.12
341
2709
233
1754
1.39
4.78
2.6
2.6
20.90
23.17
%
1.81
206
1500
1442
13889
1.57
4.75
27.0
21.6
6.95
6.74
e9/l
2.06
1416
13483
66
374
1.80
4.74
2.7
3.5
—
—
—
0
0
180
1297
1.44
4.74
1.5
1.6
—
—
—
0
0
1442
13890
1.57
4.73
26.9
21.5
30.26
30.37
pg
1.74
1434
13667
1441
13880
1.57
4.71
27.3
21.7
40.46
40.22
%
0.86
1358
12981
695
6085
1.26
4.68
4.3
3.7
0.00
0.00
estimate
0.50
151
1250
86
531
1.66
4.56
1.2
1.2
—
—
—
0
0
1292
12217
1.35
4.55
4.9
4.6
6.03
6.00
mmol/l
0.36
1209
11077
1239
11646
1.32
4.54
6.3
5.8
40.12
40.11
mmol/mol
0.01
1163
10764
27
111
2.46
4.48
2.1
1.3
—
—
—
0
0
226
1711
1.38
4.48
5.2
5.9
1.03
1.03
mmol/l
0.01
210
1580
191
1409
1.41
4.41
2.1
2.3
152.07
142.84
ug/g
0.14
155
1125
407
3360
1.29
4.41
1.7
1.7
1.46
1.39
mmol/l
0.68
338
2790
308
2450
1.32
4.40
4.3
3.8
294.09
368.00
ng/l
0.28
239
1936
38
183
2.10
4.38
2.3
1.6
0.77
0.83
g/l
0.12
29
139
489
4140
1.27
4.30
3.5
3.3
34.18
34.16
u/l
0.00
466
3931
173
1260
1.42
4.30
1.6
1.5
—
—
—
0
0
697
6146
1.24
4.29
4.3
3.7
0.00
0.01
estimate
1.08
140
1128
35
166
2.13
4.21
1.2
1.3
0.64
0.67
nmol/l
0.20
35
157
912
8292
1.24
4.21
3.2
3.2
47.40
52.06
u/l
1.02
855
7724
258
2016
1.34
4.16
2.6
2.5
11.73
13.10
umol/l
2.35
242
1883
26
109
2.41
4.15
2.0
1.3
3.33
2.78
g/l
0.65
18
73
26
109
2.41
4.15
2.0
1.3
0.36
0.37
g/l
0.02
18
73
26
109
2.41
4.15
2.0
1.3
6.95
7.04
g/l
0.05
18
75
182
1348
1.40
4.11
9.5
8.7
95.67
95.63
%
0.03
174
1298
206
1558
1.37
4.10
1.5
1.6
—
—
—
0
0
687
6079
1.23
4.00
5.8
4.9
0.00
0.00
estimate
-0.00
147
1176
33
157
2.13
3.95
1.2
1.3
—
—
—
0
0
238
1852
1.34
3.94
2.6
2.5
2.29
2.30
g/l
0.09
221
1723
170
1255
1.40
3.92
4.1
3.6
—
7.39
—
0
8
169
1250
1.40
3.86
10.0
9.1
119.71
121.68
g/l
0.54
164
1215
113
775
1.49
3.86
1.7
1.8
1.37
1.43
g/l
0.12
100
712
405
3392
1.26
3.84
3.1
2.8
6000.17
6076.36
umol/l
0.01
350
2963
118
823
1.47
3.71
11.7
9.9
93.70
93.77
%
0.05
118
816
191
1451
1.36
3.71
2.3
2.6
1.83
1.80
%
0.13
175
1299
117
817
1.47
3.66
11.8
9.9
0.65
0.68
%
0.33
117
811
338
2786
1.27
3.64
2.0
1.7
1.32
1.24
mg/l
0.19
278
2144
65
400
1.65
3.56
1.3
1.4
30.31
27.84
iu/l
0.24
51
335
19
74
2.59
3.55
1.1
1.1
—
—
—
0
0
50
287
1.77
3.51
2.5
2.7
—
—
—
0
0
57
341
1.70
3.47
1.8
2.0
10.34
11.89
mg/l
0.89
50
312
41
225
1.84
3.35
1.4
1.6
—
—
—
0
0
367
3083
1.25
3.34
2.4
2.4
—
—
—
0
0
160
1211
1.36
3.20
4.2
3.6
1.93
1.97
mmol/l
0.06
141
993
1300
12446
1.28
3.15
4.7
4.5
4.53
4.62
mmol/l
2.34
1223
11494
1291
12354
1.27
3.10
4.6
4.4
1.39
1.44
mmol/l
3.65
1207
11335
141
1052
1.37
3.09
3.4
3.8
1.23
1.23
mmol/l
0.54
127
913
101
711
1.45
3.07
11.9
11.3
—
—
—
0
0
40
226
1.79
3.00
1.1
1.2
—
—
—
0
0
281
2317
1.26
2.99
1.5
1.5
2.44
2.55
g/l
0.46
168
1434
21
94
2.25
2.97
1.2
1.2
0.39
0.86
u/ml
0.51
13
53
29
148
1.98
2.96
1.1
1.3
—
—
nmol/l
—
0
0
551
4878
1.20
2.95
4.1
3.4
5.66
5.78
ph
0.40
35
349
437
3784
1.22
2.95
3.2
3.0
1172.31
1378.30
ng/l
0.72
383
3231
124
914
1.39
2.93
1.5
1.4
—
—
—
0
0
30
156
1.94
2.91
1.0
1.0
0.55
2.63
u/ml
1.96
20
80
144
1092
1.35
2.86
2.3
2.8
77.20
70.40
e9/l
1.19
108
848
24
116
2.09
2.83
1.3
1.1
—
—
—
0
0
180
1413
1.31
2.82
1.2
1.3
—
—
—
0
0
37
210
1.78
2.76
1.5
1.4
—
—
—
0
0
28
145
1.95
2.76
1.7
1.7
—
—
—
0
0
48
295
1.65
2.71
1.2
1.4
9.86
9.17
u/l
0.12
38
239
1317
12679
1.26
2.70
5.3
5.0
2.66
2.73
mmol/l
2.07
1236
11637
48
297
1.64
2.64
3.1
5.0
2.59
2.52
mmol/l
0.06
33
203
73
502
1.48
2.55
1.1
1.1
—
—
—
0
0
52
332
1.59
2.54
2.1
1.6
294.00
286.46
mu/l
0.08
45
299
54
348
1.57
2.54
1.1
1.2
48.33
91.48
titre
—
6
27
13
50
2.61
2.53
3.7
2.8
—
—
—
0
0
78
546
1.45
2.49
1.8
1.9
—
—
—
0
0
134
1034
1.32
2.40
2.2
2.2
12.85
12.94
nmol/l
0.04
120
929
1245
11950
1.22
2.40
4.1
4.0
1.38
1.31
mmol/l
2.27
1150
10886
7
17
4.13
2.36
1.3
1.0
—
—
—
0
0
7
17
4.13
2.36
1.3
1.0
—
—
—
0
0
7
17
4.13
2.36
1.3
1.0
—
—
—
0
0
29
162
1.81
2.32
1.0
1.0
0.48
1.80
u/ml
0.96
13
70
39
238
1.66
2.30
1.6
1.6
—
—
—
0
0
116
888
1.33
2.21
4.2
5.6
—
—
—
0
0
93
688
1.37
2.21
2.7
3.3
4.30
4.49
pmol/l
0.99
83
601
29
165
1.77
2.20
1.0
1.0
4.48
4.71
u/ml
0.03
15
84
48
313
1.55
2.18
2.0
2.4
—
—
—
0
0
146
1157
1.29
2.18
2.1
2.5
7.79
7.09
ug/l
0.14
130
1036
345
3003
1.19
2.15
1.6
1.6
20.13
20.52
nmol/l
0.20
308
2552
104
791
1.34
2.09
1.2
1.2
—
—
—
0
0
9
31
2.91
2.07
1.3
1.1
—
—
—
0
0
83
611
1.38
2.05
2.0
1.8
1.69
1.56
g/l
0.56
70
535
32
192
1.68
2.04
1.1
1.1
1.54
2.50
u/ml
0.33
17
107
137
1089
1.28
2.01
4.0
3.9
—
—
—
0
0
421
3754
1.17
1.95
3.4
3.1
—
—
—
0
0
28
164
1.72
1.95
1.2
1.2
—
—
—
0
0
31
187
1.67
1.95
2.2
2.5
—
—
—
0
0
116
908
1.30
1.92
2.5
2.5
—
—
—
0
0
86
646
1.35
1.90
2.5
2.4
—
—
—
0
0
107
831
1.31
1.88
2.2
2.5
7.72
22.17
au/ml
—
6
65
33
206
1.62
1.83
1.1
1.1
—
—
—
0
0
135
1088
1.26
1.79
2.5
2.8
65.17
66.54
g/l
1.45
124
995
6
18
3.34
1.74
1.3
1.7
—
—
—
0
0
450
4064
1.15
1.74
3.4
3.2
7.21
7.68
mmol/l
1.52
388
3430
234
2005
1.20
1.74
1.3
1.2
10.45
11.19
u/ml
0.06
74
775
425
3824
1.15
1.73
3.6
3.3
884.66
339.49
mg/l
0.93
285
2481
20
110
1.83
1.73
1.5
1.6
—
—
—
0
0
113
896
1.28
1.72
1.2
1.2
—
—
—
0
0
95
736
1.31
1.72
1.4
1.3
121.18
242.23
u/ml
2.06
90
671
37
242
1.54
1.71
1.3
1.2
57.68
45.64
u/ml
—
5
18
145
1191
1.24
1.65
6.9
7.7
9.75
9.85
mmol/l
0.06
139
1141
45
310
1.47
1.65
1.4
1.7
34071.83
16794.67
e6/l
0.60
23
225
149
1228
1.24
1.65
2.4
2.3
0.23
0.21
g/l
2.04
142
1150
131
1065
1.25
1.64
4.2
4.3
0.92
0.91
%
0.01
54
392
96
751
1.30
1.63
1.2
1.3
63.73
59.23
au/ml
—
6
46
39
262
1.50
1.61
2.9
3.6
57.82
57.90
%
0.02
39
262
276
2416
1.17
1.61
1.9
1.7
1098.46
1187.55
nmol/l
1.00
221
1809
294
2589
1.17
1.59
1.3
1.2
1.24
1.56
u/ml
0.31
76
681
19
106
1.80
1.59
1.4
1.1
134.00
148.33
titre
—
5
18
541
4976
1.13
1.58
4.2
3.7
153.07
56.78
ng/l
0.38
375
3575
192
1633
1.20
1.56
1.5
1.3
532.50
517.29
titre
0.04
48
354
120
975
1.25
1.52
1.4
1.3
—
—
—
0
0
120
975
1.25
1.52
3.7
4.1
0.89
0.69
%
0.34
46
340
7
27
2.60
1.51
1.4
1.7
—
—
—
0
0
120
976
1.25
1.51
4.3
3.9
92.20
90.72
ng/l
0.06
106
858
416
3772
1.14
1.50
3.9
3.9
—
—
—
0
0
25
154
1.63
1.50
1.6
1.3
79.95
45.34
mu/l
0.43
20
139
63
470
1.35
1.50
2.3
2.0
21.04
21.49
s
0.33
51
423
368
3310
1.15
1.50
4.8
4.0
0.00
0.00
estimate
0.69
136
1128
10
45
2.23
1.46
2.3
2.5
—
—
—
0
0
37
252
1.48
1.46
2.9
3.3
4.10
4.38
e9/l
0.31
37
252
18
102
1.77
1.45
1.9
2.1
12.88
10.77
%
0.75
18
102
42
294
1.44
1.45
2.2
4.1
—
—
—
0
0
57
423
1.36
1.42
3.6
3.6
35.74
82.91
mg/l
0.81
41
343
122
1003
1.23
1.41
4.3
4.4
0.09
0.12
%
0.37
47
330
40
281
1.43
1.37
1.6
1.8
2.91
5.30
iu/l
2.24
15
92
442
4050
1.13
1.35
4.2
3.9
6.33
9.29
mg/mmol
1.29
294
2585
21
128
1.65
1.33
2.4
3.6
—
—
—
0
0
45
326
1.39
1.31
1.2
1.1
0.69
7.12
u/ml
—
10
32
22
137
1.61
1.29
1.0
1.0
8.03
3.39
u/ml
0.68
14
67
28
185
1.52
1.29
2.1
2.3
—
—
—
0
0
56
422
1.34
1.28
3.6
3.6
42.41
65.98
mg/l
0.80
40
341
5
18
2.78
1.28
2.0
1.6
—
—
—
0
0
40
285
1.41
1.28
2.2
2.7
15.50
16.28
%
0.27
13
148
18
107
1.69
1.26
1.0
1.0
0.02
0.64
u/ml
—
6
35
30
203
1.49
1.25
1.0
1.1
—
—
—
0
0
48
356
1.36
1.23
1.0
1.1
—
—
—
0
0
18
108
1.67
1.22
1.4
1.4
—
—
—
0
0
236
2091
1.15
1.20
1.3
1.3
23.59
32.06
iu/ml
1.07
65
681
126
1064
1.20
1.15
3.8
3.3
—
—
—
0
0
49
370
1.33
1.14
1.6
1.5
262.78
283.60
ug/g
0.32
34
211
14
80
1.76
1.13
1.9
4.3
—
—
—
0
0
101
840
1.22
1.09
6.8
7.9
24.91
24.48
mmol/l
0.65
95
799
14
82
1.71
1.05
2.4
2.8
34.78
40.32
%
—
9
45
23
154
1.50
1.04
1.6
1.6
79.20
62.22
%
1.77
15
102
8
148
0.54
1.03
1.1
1.1
—
—
—
0
0
15
91
1.65
1.00
1.1
1.5
1.09
1.21
promille
—
10
73
18
273
0.66
0.99
5.7
3.8
24.21
27.10
mg/l
0.14
11
179
15
92
1.64
0.97
2.2
1.6
1.01
1.00
g/l
0.05
15
92
37
276
1.35
0.96
1.5
2.3
133.71
129.39
g/l
0.42
24
213
35
259
1.36
0.95
1.5
1.3
—
—
—
0
0
24
166
1.45
0.94
1.3
1.0
1.18
2.25
u/ml
1.38
14
68
362
3346
1.11
0.94
1.4
1.4
—
—
—
0
0
111
948
1.18
0.93
4.3
4.4
0.05
0.42
%
0.60
37
277
10
55
1.82
0.92
1.0
1.3
135.60
167.87
mmol/24h
—
10
55
14
86
1.63
0.91
1.9
1.1
—
—
—
0
0
91
1075
0.84
0.90
1.3
1.4
—
—
—
0
0
52
413
1.27
0.88
1.1
1.1
—
—
—
0
0
32
237
1.36
0.88
1.5
1.3
111.38
123.87
u/ml
—
8
42
18
119
1.52
0.88
1.4
1.9
—
—
—
0
0
7
130
0.54
0.88
1.4
1.2
—
—
—
0
0
10
56
1.79
0.88
1.0
1.2
151.60
229.50
iu/ml
—
10
56
148
1302
1.15
0.87
1.6
1.6
—
—
—
0
0
21
144
1.46
0.87
1.4
2.3
—
—
—
0
0
8
43
1.86
0.87
2.6
2.0
136.00
53.69
ug/l
—
8
43
29
213
1.37
0.84
1.7
1.5
—
—
—
0
0
8
45
1.78
0.84
2.0
1.3
—
—
—
0
0
11
65
1.70
0.82
1.1
1.4
—
—
—
0
0
43
337
1.28
0.82
1.1
1.1
—
—
—
0
0
41
321
1.28
0.79
1.4
1.2
19.12
11.61
u/ml
—
5
49
17
114
1.50
0.79
1.6
1.4
22.64
30.34
%
0.44
11
72
6
33
1.82
0.79
1.0
1.4
—
—
—
0
0
65
539
1.21
0.78
2.1
2.7
—
—
—
0
0
15
222
0.67
0.77
1.5
3.3
—
—
—
0
0
40
314
1.28
0.77
4.2
3.7
—
—
—
0
0
64
531
1.21
0.76
4.7
4.9
—
—
—
0
0
15
99
1.52
0.75
1.1
1.2
—
—
—
0
0
40
315
1.28
0.75
1.4
1.2
1.82
2.48
u/ml
—
5
29
7
38
1.85
0.73
1.1
1.0
—
—
—
0
0
66
553
1.20
0.72
2.2
2.0
5.81
1.94
ug/l
0.70
60
491
18
126
1.43
0.70
1.1
1.0
5.75
4.02
u/ml
—
10
52
21
153
1.38
0.67
1.1
1.3
—
—
—
0
0
92
801
1.16
0.66
3.0
2.9
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
47.80
32.54
nmol/l
—
5
22
74
635
1.17
0.64
4.2
3.6
—
—
—
0
0
38
305
1.25
0.64
6.1
9.0
103.52
105.58
mmol/l
1.29
33
276
38
305
1.25
0.64
6.1
9.0
12.18
11.28
mmol/l
0.38
33
276
5
29
1.73
0.64
4.8
6.4
—
—
—
0
0
57
479
1.20
0.63
1.9
2.3
878.87
448.23
ug/l
0.41
51
455
8
49
1.64
0.62
1.0
1.1
—
—
—
0
0
10
63
1.59
0.62
2.2
3.0
1037.30
1404.27
u/ml
—
10
63
289
2702
1.09
0.61
5.1
4.0
1.01
1.02
kg/l
1.34
39
389
0
20
0.00
0.60
0.0
1.0
—
3.71
—
0
15
22
166
1.33
0.58
1.3
3.2
—
—
—
0
0
10
64
1.57
0.58
5.9
7.5
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
241.67
289.61
pmol/l
—
6
23
14
98
1.43
0.56
1.0
1.1
—
—
titre
—
0
0
11
73
1.51
0.56
2.0
1.6
0.82
5.31
u/field
1.16
11
54
17
124
1.38
0.55
2.2
2.4
—
—
—
0
0
6
38
1.58
0.54
1.5
1.7
174.37
101.13
nmol/24h
—
6
38
16
117
1.37
0.52
1.1
1.2
—
—
—
0
0
506
4860
1.06
0.51
5.0
4.8
2.34
2.68
ug/l
0.51
450
4356
40
334
1.20
0.50
1.6
2.2
114.44
106.69
ug/min
0.06
18
203
10
67
1.50
0.49
1.2
1.7
—
—
—
0
0
17
127
1.34
0.49
1.0
1.2
—
—
—
0
0
17
127
1.34
0.49
1.9
1.4
—
—
—
0
0
62
708
0.87
0.47
1.4
1.4
—
—
—
0
0
36
300
1.20
0.47
1.5
1.6
—
—
—
0
0
7
49
1.43
0.46
1.1
1.2
—
17.14
—
0
7
47
403
1.17
0.45
4.3
4.3
3.84
3.92
mmol/l
0.65
47
398
23
286
0.80
0.44
1.7
1.7
—
—
—
0
0
115
1258
0.91
0.44
4.8
4.5
—
—
—
0
0
10
69
1.45
0.44
1.0
1.0
—
—
—
0
0
62
545
1.14
0.44
5.1
6.3
1.81
1.62
%
0.50
56
511
33
275
1.20
0.43
1.2
2.0
0.87
0.83
nmol/l
0.16
27
230
22
274
0.80
0.43
5.0
3.3
8.25
7.53
mmol/l
0.64
22
268
34
286
1.19
0.41
1.5
1.5
19928.21
807.08
e6/l
0.53
28
229
34
286
1.19
0.41
1.5
1.4
30.07
40.18
e6/l
0.15
27
220
0
16
0.00
0.41
0.0
1.4
—
6.24
—
0
11
0
16
0.00
0.41
0.0
1.3
—
48.56
—
0
16
0
16
0.00
0.41
0.0
2.6
—
—
—
0
0
14
105
1.34
0.41
1.0
1.1
—
66.64
—
0
5
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
61
1.31
0.39
1.1
1.2
—
—
—
0
0
17
133
1.28
0.38
1.8
1.5
—
—
—
0
0
84
762
1.11
0.38
1.1
1.2
78.04
143.04
iu/ml
1.95
37
301
9
67
1.35
0.38
1.3
3.0
—
—
—
0
0
10
136
0.73
0.37
1.0
1.1
—
—
—
0
0
61
544
1.13
0.37
5.1
6.3
0.88
0.89
%
0.09
56
511
9
71
1.27
0.36
1.0
1.3
1.55
1.12
nmol/l
—
9
55
12
90
1.34
0.35
3.0
2.3
—
—
—
0
0
5
79
0.63
0.35
43.0
20.4
1570.00
1500.78
nmol/l
—
5
79
29
245
1.19
0.35
1.4
3.5
—
—
—
0
0
10
73
1.37
0.34
2.3
1.9
—
48.30
—
0
5
18
145
1.24
0.33
1.6
1.5
—
—
—
0
0
77
844
0.91
0.33
4.1
3.5
7.41
7.40
ph
—
9
115
16
127
1.26
0.33
1.3
1.4
0.25
0.33
nmol/l
—
10
99
34
294
1.16
0.32
1.5
2.4
—
—
—
0
0
33
285
1.16
0.32
2.0
1.9
205.33
217.23
pmol/l
0.23
33
269
261
2726
0.95
0.32
1.8
1.7
61818627.25
30539883.58
pmol/l
0.31
220
2243
35
304
1.15
0.32
2.6
3.3
29.77
34.77
umol/l
0.92
30
273
88
811
1.09
0.31
1.6
1.6
—
—
—
0
0
7
54
1.30
0.30
1.1
1.5
—
—
—
0
0
10
75
1.34
0.30
1.0
1.1
—
—
—
0
0
42
373
1.13
0.29
1.3
2.1
—
—
—
0
0
42
374
1.13
0.28
1.3
2.2
—
—
—
0
0
42
375
1.12
0.27
1.3
2.2
—
—
—
0
0
22
258
0.85
0.27
1.4
1.3
—
—
—
0
0
42
376
1.12
0.26
1.3
2.1
—
—
—
0
0
79
852
0.92
0.26
4.1
3.6
5.12
5.13
kpa
0.03
74
821
56
613
0.91
0.26
4.8
3.6
—
—
—
0
0
19
160
1.19
0.25
1.7
1.4
625.36
1623.77
e6/l
3.25
11
112
9
74
1.22
0.25
1.0
2.9
—
—
—
0
0
18
151
1.19
0.25
1.4
1.2
—
—
—
0
0
6
82
0.73
0.24
2.0
2.1
1.00
1.85
ug/l
—
6
70
6
83
0.72
0.24
2.0
2.0
2.33
2.96
ug/l
—
6
75
6
85
0.70
0.24
2.3
1.6
—
—
—
0
0
70
649
1.08
0.23
1.3
1.2
—
—
—
0
0
17
143
1.19
0.23
1.8
1.4
44158.57
107055.12
e6/l
—
7
83
5
38
1.32
0.23
7.8
4.6
—
—
—
0
0
432
4425
0.97
0.23
2.9
2.9
—
—
—
0
0
290
2810
1.04
0.23
3.0
3.0
0.82
0.75
ug/l
0.52
195
1848
14
168
0.83
0.22
3.4
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
29
258
1.13
0.21
1.5
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
173.20
—
0
5
11
134
0.82
0.20
3.1
2.6
—
—
—
0
0
10
123
0.81
0.20
1.0
1.3
5824.60
158915.68
e6/l
—
5
84
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
40
366
1.10
0.19
1.2
1.2
—
—
—
0
0
7
60
1.17
0.17
17.0
11.7
0.67
0.62
mmol/l
—
7
55
38
349
1.09
0.17
1.3
2.2
—
—
—
0
0
30
273
1.10
0.16
2.6
3.1
0.86
0.84
nmol/l
0.05
25
212
13
111
1.17
0.15
1.0
1.2
—
—
—
0
0
13
151
0.86
0.15
1.7
2.5
0.24
1.47
g/24h
—
5
75
31
338
0.92
0.15
6.6
4.7
—
—
—
0
0
15
131
1.15
0.14
1.9
1.6
—
—
—
0
0
12
139
0.86
0.14
1.2
1.5
—
—
—
0
0
10
84
1.19
0.14
1.1
1.4
—
—
—
0
0
15
170
0.88
0.13
1.1
1.3
—
—
—
0
0
22
241
0.91
0.12
1.1
1.4
—
—
—
0
0
22
201
1.10
0.11
1.1
1.1
—
—
—
0
0
22
201
1.10
0.11
1.1
1.1
—
—
—
0
0
10
86
1.16
0.11
1.4
1.1
—
—
—
0
0
86
831
1.04
0.10
3.3
3.1
4.01
5.94
e9/l
1.47
74
671
5
45
1.11
0.09
1.4
1.6
—
—
—
0
0
26
242
1.08
0.09
1.8
2.2
3616.37
3325.26
u/l
—
7
99
5
47
1.06
0.09
1.8
1.6
—
—
—
0
0
11
97
1.13
0.09
2.1
2.0
51.34
38.13
%
1.49
11
97
137
1338
1.03
0.09
3.7
4.3
64.85
22.47
ug/l
0.32
110
1105
5
60
0.83
0.08
1.0
1.1
—
357.40
—
0
15
27
254
1.06
0.07
2.3
2.7
—
—
—
0
0
12
133
0.90
0.07
1.2
1.4
—
—
—
0
0
12
133
0.90
0.07
1.2
1.4
—
—
—
0
0
8
75
1.07
0.07
1.1
1.4
1.56
1.56
g/l
—
8
75
20
214
0.93
0.07
1.4
1.4
—
—
—
0
0
39
407
0.96
0.06
16.3
10.5
—
—
—
0
0
9
104
0.86
0.06
1.1
1.1
450.33
380.62
nmol/l
—
9
89
337
3339
1.01
0.06
3.7
3.3
—
—
—
0
0
10
90
1.11
0.05
1.4
1.4
133.61
164.61
pmol/l
—
10
90
50
516
0.97
0.05
4.3
3.9
24.56
24.84
mmol/l
0.27
45
485
43
416
1.03
0.05
1.5
1.7
—
—
—
0
0
26
249
1.04
0.04
1.1
1.2
189.49
279.41
u/ml
1.08
13
149
14
133
1.05
0.01
1.4
2.2
—
—
—
0
0
15
143
1.05
0.01
2.7
4.4
—
—
—
0
0
51
503
1.01
0.01
3.6
3.4
12059.00
2959.63
u/ml
0.34
44
426
12
124
0.97
0.00
1.1
1.2
—
—
—
0
0
32
316
1.01
0.00
1.5
1.3
226.33
238.99
miu/ml
0.07
15
139
11
108
1.02
0.00
1.7
2.4
595.83
619.28
ml
—
6
69
13
132
0.98
0.00
1.1
1.2
—
—
—
0
0
14
142
0.99
0.00
1.7
1.4
—
—
—
0
0
30
298
1.01
0.00
1.1
1.2
—
—
—
0
0
19
189
1.01
0.00
1.3
1.2
2.13
6.20
u/ml
—
8
83
46
465
0.99
0.00
1.9
3.5
0.20
0.26
g/l
0.58
18
194
55
555
0.99
0.00
1.4
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
87.75
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
15.21
—
0
7
0
7
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.1
—
—
—
0
0
7
76
0.92
-0.00
1.3
1.2
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.2
—
—
—
0
0
8
85
0.94
-0.00
2.3
1.1
40.50
34.24
mmol/l
—
8
79
7
76
0.92
-0.00
1.6
1.5
—
—
—
0
0
9
95
0.95
-0.00
1.4
1.5
77.22
84.06
umol/l
—
9
95
0
7
0.00
-0.00
0.0
1.6
—
403.14
—
0
7
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.3
3.92
5.79
ug/l
—
6
54
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
68
0.88
-0.00
1.7
1.9
9.32
9.99
mmol/l
—
6
68
6
67
0.90
-0.00
3.0
2.5
56183.33
40376.19
ug/l
—
6
67
7
71
0.99
-0.00
2.0
1.2
128.86
145.73
nmol/l
—
7
71
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
168.20
—
0
5

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_EAR_NASAL_SINUS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_EAR_NASAL_SINUS 1.289 [1.13, 1.47] < 0.001
Birth year 0.995 [0.99, 1.0] 0.221

During the follow-up period (1.1.1998 — 31.12.2019), 531 out of 3276 females with CD2_BENIGN_EAR_NASAL_SINUS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_EAR_NASAL_SINUS 1.197 [0.99, 1.44] 0.058
Birth year 0.989 [0.94, 1.04] 0.691

During the follow-up period (1.1.1998 — 31.12.2019), 689 out of 3623 males with CD2_BENIGN_EAR_NASAL_SINUS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_EAR_NASAL_SINUS.

N-year risk Females Males
1 0.15% 0.216%
5 0.85% 1.352%
10 2.003% 3.63%
15 3.69% 6.902%
20 6.21% 11.55%

Relationships between endpoints

Index endpoint: CD2_BENIGN_EAR_NASAL_SINUS – Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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