No definition available.
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
EFO MESH Endpoint Browser PheWeb
CD2_BENIGN_EAR_NASAL_SINUS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1476 |
4. Check minimum number of eventsNone |
1476 |
5. Include endpointsNone |
1476 |
6. Filter based on genotype QC (FinnGen only) |
1476 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D14
- Name in latin
- Neoplasma benignum auris mediae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9658 | 4526 | 5061 |
| Only index persons | 8673 | 4172 | 4501 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.13 | 0.14 |
| Only index persons | 0.16 | 0.15 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 53.85 | 54.43 | 53.29 |
| Only index persons | 52.85 | 53.43 | 52.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1476 | 692 | 784 |
| Unadjusted period prevalence (%) | 0.29 | 0.24 | 0.35 |
| Median age at first event (years) | 56.09 | 54.05 | 57.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1324
- Matched controls
- 13240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
+∞
323.0
1167
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
434.1
225.7
220
6
DHA10
NOMESCO Finland
Biopsy of cavity of nose
96.2
218.2
238
30
UDH02
NOMESCO Finland
Rhinopharyngoscopy
13.2
206.1
391
408
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
10.2
126.0
266
317
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
146.4
114.2
120
9
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
11.2
98.4
195
201
UDM02
NOMESCO Finland
Sinoscopy
17.3
95.0
154
100
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
13.2
92.4
168
144
2120A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Nasal cavities, middle ear and accessory sinuses
+∞
89.6
85
*
J33.0
ICD-10 Finland
Polyp of nasal cavity
11.1
74.9
148
149
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
74.5
74.2
84
12
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
5.6
72.9
232
482
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
34.0
56.7
74
23
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.3
54.9
225
601
DHB20
NOMESCO Finland
Polypectomy of internal nose
16.1
54.1
89
59
R01AD08
ATC
fluticasone; nasal
2.7
51.5
476
2304
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
180.2
50.3
52
*
J33.8
ICD-10 Finland
Other polyp of sinus
9.9
49.8
103
112
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
49.3
47
*
DPA30
NOMESCO Finland
Sphenotomy
30.1
49.2
66
23
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
127.1
46.1
49
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.4
44.4
122
206
DHB40
NOMESCO Finland
Conchotomy
72.5
43.3
49
7
R01AD09
ATC
mometasone; nasal
2.2
41.7
649
3985
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
41.4
450
2318
DMB10
NOMESCO Finland
Radical maxillary antrotomy
31.2
40.8
54
18
21200
ICD-8 Finland
Benign neoplasm of respiratory system, Cavi nasi
+∞
35.6
34
*
DMB30
NOMESCO Finland
Transmaxillary excision of lesion of maxillary antrum
126.8
34.9
37
*
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
17.3
34.8
55
33
21202
ICD-8 Finland
Benign neoplasm of respiratory system, Sinus maxillaris
+∞
34.5
33
*
4256
FHL
Nasal or sinus tumor removal
+∞
34.5
33
*
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
17.2
33.5
53
32
DJW00
NOMESCO Finland
Removal of local lesion of nasal septum
335.1
33.0
33
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
7.8
32.7
77
104
J33.9
ICD-10 Finland
Nasal polyp, unspecified
13.5
32.1
56
43
ZXC10
NOMESCO Finland
Use of laser
8.0
30.8
71
93
DHB00
NOMESCO Finland
Excision of lesion of external nose
14.9
29.4
49
34
J31.0
ICD-10 Finland
Chronic rhinitis
3.4
27.7
145
466
R04.0
ICD-10 Finland
Epistaxis
3.2
26.3
148
500
DKW40
NOMESCO Finland
Ligature of artery of internal nose
51.1
25.3
30
6
DMB35
NOMESCO Finland
Endoscopic excision of neoplasm or another lesion from maxillary sinus
+∞
25.1
24
*
R01AD12
ATC
fluticasone furoate; nasal
2.0
24.7
393
2296
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
24.4
674
4794
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
9.9
24.4
49
51
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
49.3
24.3
29
6
B977, D140
ICD-10 Finland
NA
+∞
23.0
22
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.4
22.8
115
358
WX110
NOMESCO Finland
Local anesthesy
1.8
21.2
881
6996
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
21.2
300
1656
DNB40
NOMESCO Finland
Sublabial rhinotomy
111.8
20.6
22
*
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
33.1
20.2
26
8
ZXC95
NOMESCO Finland
Use of surgical navigator
10.0
20.2
40
41
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
36.4
19.9
25
7
H02AB06
ATC
prednisolone; systemic
1.7
19.6
622
4504
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
19.4
287
1607
ZXA05
NOMESCO Finland
Left side
1.9
19.3
368
2264
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
17.4
18.7
29
17
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.2
18.2
71
178
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
8.3
17.8
39
48
J32.1
ICD-10 Finland
Chronic frontal sinusitis
20.4
17.8
26
13
J34.2
ICD-10 Finland
Deviated nasal septum
3.2
17.4
92
298
WX002
NOMESCO Finland
Sedation and analgesia
1.9
17.0
285
1664
8070/3-C30.0
ICD-O-3
Squamous cell carcinoma, NOS, of nasal cavity
+∞
16.7
16
*
DHB50
NOMESCO Finland
Turbinoplasty
4.5
16.1
57
131
J01DB01
ATC
cefalexin; oral
1.7
15.9
1041
8985
J34.1
ICD-10 Finland
Cyst and mucocele of nose and nasal sinus
6.1
15.8
43
73
J01CA04
ATC
amoxicillin; systemic
1.7
15.4
1009
8654
WX402
NOMESCO Finland
General anaesthesia
2.0
15.3
225
1245
DJA10
NOMESCO Finland
Biopsy of septum of nose
57.3
14.8
17
*
DPW99
NOMESCO Finland
Other operation on frontal or sphenoidal sinus
21.3
14.7
21
10
D38.50
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of maxillary sinus
151.6
14.5
15
*
DPB00
NOMESCO Finland
Partial excision of frontal sinus
30.4
13.9
18
6
ZXA00
NOMESCO Finland
Right side
1.7
13.7
377
2549
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.3
13.6
69
217
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
16.4
13.5
21
13
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.8
13.3
242
1441
ZXA10
NOMESCO Finland
Bilateral
1.8
13.3
253
1530
UDQ22
NOMESCO Finland
Microlaryngoscopy
8.6
13.3
28
33
J01AA02
ATC
doxycycline; systemic
1.6
13.2
984
8501
R01AD01
ATC
beclometasone; nasal
1.9
13.1
204
1150
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.0
554
4185
DPA20
NOMESCO Finland
Trephine of frontal sinus
22.8
12.9
18
8
D10.6
ICD-10 Finland
Benign neoplasm: Nasopharynx
17.5
12.5
19
11
DMB40
NOMESCO Finland
Excision of lesion of maxillary antrum trough lateral rhinotomy
+∞
12.5
12
*
4226
FHL
Posterior radical surgery and possible etmoidectomy
9.4
12.5
25
27
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
12.3
490
3630
N02BE01
ATC
paracetamol; systemic, rectal
1.7
12.2
1082
9646
R08
ICPC
Nose symptom/complaint other
3.5
12.1
56
165
J01FA10
ATC
azithromycin; systemic
1.5
12.0
682
5464
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
6.6
11.6
29
45
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
121.0
11.4
12
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
11.3
567
4396
J32.4
ICD-10 Finland
Chronic pansinusitis
5.0
10.9
34
70
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
10.6
55
178
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
10.3
218
1355
D38.58
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other respiratory organ
32.8
10.3
13
*
DMA10
NOMESCO Finland
Exploration of maxillary antrum
23.6
10.2
14
6
DQA10
NOMESCO Finland
Biopsy of larynx
10.1
10.0
19
19
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
3.5
9.8
44
128
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.7
438
3294
R06AX22
ATC
ebastine; oral
1.7
9.6
200
1234
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
4.4
9.6
33
76
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
100.7
9.4
10
*
R4110
NOMESCO Finland
Physiotherapy
1.6
9.4
324
2288
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
9.4
271
1835
DPB10
NOMESCO Finland
Partial excision of sphenoidal sinus
+∞
9.4
9
*
DPC35
NOMESCO Finland
Extensive endoscopic excision of lesion or neoplasm extending to more than one paranasal sinus
+∞
9.4
9
*
UDC00
NOMESCO Finland
Ear microscopy
2.1
9.2
105
524
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
9.1
348
2517
A02BC02
ATC
pantoprazole; systemic
1.4
9.0
783
6663
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
7.1
9.0
21
30
J33
ICD-10 Finland
Nasal polyp
10.1
9.0
17
17
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
8.9
256
1728
R51.81
ICD-10 Finland
Facial pain NOS
3.7
8.8
37
103
4222
FHL
Endonasal etmoidectomy
7.2
8.7
20
28
R06AE07
ATC
cetirizine; oral
1.4
8.6
490
3839
R03AC02
ATC
salbutamol; inhalant
1.4
8.6
608
4962
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.6
202
1291
J01.1
ICD-10 Finland
Acute frontal sinusitis
4.5
8.6
29
66
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
8.5
131
734
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
8.4
209
1354
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.4
406
3074
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.4
282
1975
DKW30
NOMESCO Finland
Cauterisation of artery of internal nose
6.8
8.4
20
30
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
8.3
61
248
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.9
8.3
122
671
A07AA02
ATC
nystatin; oral
2.2
8.3
85
407
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
5.0
8.2
25
51
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.2
438
3382
4239
FHL
Other measure in this category
9.0
8.0
16
18
J32.8
ICD-10 Finland
Other chronic sinusitis
10.1
8.0
15
15
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
8.0
1105
10158
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.4
7.9
67
293
J01MA12
ATC
levofloxacin; systemic
1.6
7.8
226
1526
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
7.7
170
1065
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
7.7
377
2855
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.6
253
1764
M31.3
ICD-10 Finland
Wegener granulomatosis
11.9
7.6
13
11
WF002
NOMESCO Finland
Radical radiotherapy
2.3
7.6
68
307
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
10.1
7.5
14
14
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.8
7.5
46
169
B07.9
ICD-10 Finland
Verruca simplex
2.8
7.5
45
163
J01FF01
ATC
clindamycin; systemic
1.5
7.5
319
2347
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.3
804
6999
21208
ICD-8 Finland
Benign neoplasm of respiratory system, Nasi, loco multiplici
+∞
7.3
7
*
DJB10
NOMESCO Finland
Excision of septum of nose
+∞
7.3
7
*
C72.2
ICD-10 Finland
Malignant neoplasm: Olfactory nerve
+∞
7.3
7
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
7.3
302
2209
KMAK
NOMESCO Finland
NA
1.4
7.2
577
4767
DCB00
NOMESCO Finland
Excision of lesion of middle ear
30.2
7.2
9
*
A02BC03
ATC
lansoprazole; oral
1.4
7.1
346
2608
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.1
191
1264
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.6
7.1
50
200
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.5
7.0
50
201
A02BC05
ATC
esomeprazole; systemic
1.4
7.0
467
3735
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.1
7.0
76
375
H65.3
ICD-10 Finland
Chronic mucoid otitis media
3.4
6.9
31
92
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.6
6.8
28
78
DKW99
NOMESCO Finland
Other procedures for control of epistaxis
9.4
6.8
13
14
R03DC03
ATC
montelukast; oral
1.6
6.8
173
1128
ZXC99
NOMESCO Finland
Other special technic in surgery
16.8
6.7
10
6
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.2
6.7
67
319
ZZC00
NOMESCO Finland
Graft of fascia
22.6
6.7
9
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
6.7
94
510
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.7
505
4116
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
6.5
6.6
16
25
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
6.6
183
1222
UDQ02
NOMESCO Finland
Direct laryngoscopy
4.8
6.5
20
42
R09
ICPC
Sinus symptom/complaint
2.0
6.5
79
405
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
6.9
6.5
15
22
G50.1
ICD-10 Finland
Atypical facial pain
3.5
6.5
28
81
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
6.5
87
465
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
6.5
93
511
DM1CD
NOMESCO Finland
Very extensive CT of paranasal sinuses and face area
70.2
6.4
7
*
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.0
6.4
34
116
N05CF01
ATC
zopiclone; oral
1.4
6.3
368
2860
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
6.3
531
4386
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
6.3
706
6095
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
11.1
6.3
11
10
J01DA01
ATC
[U] cefalexin; systemic
1.3
6.3
752
6560
Z01.2
ICD-10 Finland
Dental examination
1.4
6.3
441
3539
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
6.3
75
384
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.9
6.3
93
517
9522/3-C30.0
ICD-O-3
Olfactory neuroblastoma of nasal cavity
+∞
6.3
6
*
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
6.3
6
*
21209
ICD-8 Finland
Benign neoplasm of respiratory system, Nasi, NUD
+∞
6.3
6
*
B977, D141
ICD-10 Finland
NA
+∞
6.3
6
*
DM1BG
NOMESCO Finland
Paranasal sinuses and face area standard MRI examination with high intensity magnet
+∞
6.3
6
*
DPB20
NOMESCO Finland
Obliteration of frontal sinus
+∞
6.3
6
*
J01
ICD-10 Finland
Acute sinusitis
2.2
6.2
57
262
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.2
588
4945
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.2
624
5299
J01FA09
ATC
clarithromycin; systemic
1.4
6.1
351
2716
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.1
341
2626
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
6.1
385
3030
DKW10
NOMESCO Finland
Packing of anterior cavity of nose
12.6
6.1
10
8
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.1
179
1209
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
6.1
93
521
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.6
6.1
40
155
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
10.1
6.0
11
11
UJH02
NOMESCO Finland
Anoscopy
2.2
6.0
55
252
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
6.0
40
156
G47.3
ICD-10 Finland
Sleep apnoea
1.5
6.0
253
1847
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
489
3361
1.68
18.21
3.4
3.2
0.4
0.5
e6/l
0.69
362
2585
691
5202
1.62
17.81
5.0
5.0
35.3
35.4
g/l
0.10
644
4836
712
5465
1.59
16.47
6.6
6.2
1.2
1.2
mmol/l
1.01
668
4944
1086
9292
1.64
15.17
8.6
7.7
79.6
79.1
u/l
0.14
1021
8735
228
1356
1.81
13.81
2.6
2.7
5.8
8.7
umol/l
3.74
198
1200
785
6356
1.50
13.00
6.3
6.3
12.0
11.7
umol/l
0.19
743
6040
748
6015
1.49
12.69
7.4
7.0
1.2
1.2
mmol/l
0.86
625
5054
1027
8862
1.52
12.01
4.5
4.1
13.2
12.4
mm/h
0.83
957
8168
835
6909
1.48
12.01
9.8
9.1
4.3
4.2
e9/l
1.04
715
6048
306
2061
1.61
11.55
3.1
2.8
0.7
1.1
e6/l
2.33
178
1205
324
2236
1.58
10.98
2.9
3.1
2.4
2.5
mmol/l
0.08
274
1970
289
1946
1.60
10.86
3.3
2.9
2.1
2.2
e6/l
0.04
159
1094
1108
9811
1.52
10.63
22.0
18.0
13.8
13.7
%
0.64
1090
9586
912
7801
1.44
10.20
5.0
4.4
3301.9
1777.5
e6/l
—
8
113
180
1107
1.71
9.57
2.9
2.4
33.5
38.4
u/l
0.45
150
943
355
2576
1.50
9.38
2.6
2.6
4.1
5.3
e6/l
1.57
297
2279
683
5645
1.39
8.71
3.9
4.1
—
—
—
0
0
1284
11893
1.61
8.64
18.9
14.8
23.4
25.0
mg/l
1.10
1078
9444
27
75
3.65
8.58
1.3
1.3
—
—
—
0
0
514
4065
1.41
8.44
3.2
3.4
2.4
2.4
mmol/l
0.17
459
3540
277
1958
1.51
8.20
4.2
3.4
0.8
0.8
mmol/l
0.17
258
1839
611
5004
1.38
8.03
2.1
2.0
94.8
94.0
pmol/l
0.16
311
2633
830
7142
1.37
7.98
5.5
5.0
6.8
6.8
mmol/l
0.01
782
6711
1318
12348
1.63
7.72
21.2
17.2
139.6
139.7
mmol/l
0.68
1302
12021
1179
10788
1.46
7.71
5.1
4.6
1.9
2.2
mu/l
1.10
1090
9809
1227
11318
1.50
7.68
17.1
13.7
80.3
79.8
ml/min/173m2
0.30
1047
9389
1319
12383
1.61
7.37
21.3
17.3
4.0
4.0
mmol/l
1.66
1300
12039
209
1428
1.54
7.20
3.9
4.1
249.7
248.8
u/l
0.03
195
1354
999
8924
1.37
7.17
4.3
3.9
14.8
14.9
pmol/l
0.38
919
8066
57
268
2.17
6.83
1.5
1.5
—
—
—
0
0
140
883
1.65
6.76
1.6
1.7
—
—
—
0
0
476
3845
1.35
6.49
2.5
2.5
57.9
57.4
u/l
0.10
443
3564
108
645
1.73
6.40
10.2
10.4
24.7
24.4
mmol/l
0.32
99
608
162
1077
1.57
6.30
3.2
2.2
365.1
366.8
nmol/l
0.04
156
986
98
574
1.76
6.22
4.0
3.7
24.4
24.1
mmol/l
0.45
93
518
573
4796
1.32
6.01
2.4
2.2
77.5
77.1
nmol/l
0.11
515
4276
200
1426
1.47
5.58
7.9
8.1
5.1
5.1
kpa
0.11
191
1361
200
1427
1.46
5.56
7.9
8.1
13.0
12.0
kpa
1.30
190
1364
61
322
1.93
5.42
1.3
1.3
—
—
—
0
0
454
3722
1.32
5.40
2.0
2.2
188.6
228.0
u/l
0.67
428
3503
31
125
2.51
5.30
4.2
3.5
—
—
—
0
0
1336
12729
1.52
5.29
12.2
10.6
26.2
26.7
u/l
0.72
1298
12263
62
334
1.89
5.19
1.2
1.2
—
—
—
0
0
62
334
1.89
5.19
1.2
1.2
—
—
—
0
0
198
1432
1.44
5.13
8.0
8.1
1.3
1.2
mmol/l
0.19
157
1119
1160
10809
1.34
5.02
20.0
15.7
40.3
39.9
%
1.20
841
7591
234
1754
1.40
4.96
1.5
1.4
—
—
—
0
0
194
1410
1.43
4.89
1.9
1.8
—
—
—
0
0
298
2332
1.35
4.82
4.4
3.8
281.5
376.5
ng/l
0.38
230
1846
185
1337
1.44
4.81
2.1
2.3
152.2
138.6
ug/g
0.22
148
1062
662
5776
1.26
4.68
4.3
3.7
0.0
0.0
estimate
0.00
134
1110
217
1623
1.40
4.65
5.2
5.8
1.0
1.0
mmol/l
0.02
201
1503
148
1033
1.48
4.61
2.9
2.9
208.0
205.8
ng/l
0.02
136
944
191
1400
1.42
4.60
1.9
1.7
—
—
—
0
0
248
1900
1.37
4.59
2.5
2.1
30.2
29.8
s
0.36
241
1839
1374
13236
1.55
4.42
26.9
21.7
247.6
247.3
e9/l
0.06
1352
12889
577
4977
1.26
4.42
3.3
2.8
152.6
141.0
ug/l
0.24
541
4559
376
3077
1.30
4.40
2.5
2.2
3.1
3.0
mg/l
0.08
326
2603
20
71
2.84
4.39
2.2
2.3
—
—
—
0
0
1374
13242
1.54
4.34
26.9
21.6
4.5
4.5
e12/l
0.15
1347
12855
1374
13245
1.54
4.30
27.1
21.8
135.2
135.8
g/l
0.67
1366
13029
178
1305
1.41
4.28
3.8
3.4
—
—
—
0
0
465
3922
1.27
4.27
3.5
3.3
34.4
34.1
u/l
0.03
442
3728
784
7024
1.25
4.25
2.9
2.8
—
—
—
0
0
33
153
2.18
4.20
1.1
1.4
—
—
—
0
0
1373
13244
1.53
4.16
27.0
21.7
7.0
6.7
e9/l
2.31
1347
12855
665
5861
1.25
4.14
4.3
3.7
0.0
0.0
estimate
1.08
133
1081
220
1682
1.36
4.12
2.7
2.6
20.9
23.1
%
1.70
194
1441
34
162
2.12
4.05
1.2
1.3
0.6
0.7
nmol/l
0.27
34
153
389
3230
1.28
4.02
3.1
2.8
6305.8
6289.9
umol/l
0.00
332
2794
212
1620
1.36
3.98
27.2
25.7
1.4
1.4
inr
0.19
36
223
23
93
2.50
3.97
1.3
1.2
—
—
—
0
0
1180
11127
1.30
3.96
6.3
5.9
40.1
40.1
mmol/mol
0.08
1106
10281
58
335
1.76
3.96
1.5
1.7
—
—
—
0
0
1230
11669
1.32
3.91
4.9
4.6
6.0
6.0
mmol/l
0.29
1148
10581
655
5791
1.24
3.88
5.7
5.0
0.0
0.0
estimate
0.00
140
1125
866
7887
1.24
3.88
3.2
3.2
46.4
51.9
u/l
1.31
812
7343
253
2009
1.31
3.66
2.0
1.8
—
—
—
0
0
323
2650
1.28
3.64
1.9
1.7
1.3
1.2
mg/l
0.30
267
2037
245
1939
1.32
3.63
2.6
2.5
11.7
13.0
umol/l
2.02
229
1792
161
1195
1.39
3.62
9.1
9.0
119.7
121.6
g/l
0.50
154
1153
83
542
1.56
3.57
1.3
1.3
—
—
—
0
0
382
3210
1.26
3.52
1.7
1.7
1.5
1.4
mmol/l
0.86
318
2664
226
1780
1.32
3.46
2.6
2.5
2.3
2.3
g/l
0.09
210
1652
112
786
1.46
3.44
10.3
9.7
93.6
93.8
%
0.21
112
779
111
782
1.45
3.35
10.3
9.7
0.6
0.7
%
0.53
111
776
104
724
1.47
3.34
1.5
1.5
—
—
—
0
0
183
1406
1.34
3.32
2.3
2.6
1.8
1.8
%
0.05
169
1259
45
255
1.79
3.32
1.5
1.7
—
—
—
0
0
352
2952
1.25
3.28
2.4
2.4
—
—
—
0
0
60
372
1.64
3.22
1.5
1.7
—
—
—
0
0
60
375
1.63
3.13
1.4
1.4
30.5
27.4
iu/l
0.30
47
316
43
251
1.73
2.91
1.3
1.3
—
—
—
0
0
43
251
1.73
2.91
1.3
1.3
—
—
—
0
0
20
89
2.26
2.87
1.3
1.2
0.4
0.8
u/ml
—
10
44
151
1158
1.34
2.80
4.2
3.5
2.0
2.0
mmol/l
0.07
131
922
22
104
2.13
2.75
1.1
1.2
—
—
—
0
0
22
105
2.11
2.69
2.0
1.6
—
—
—
0
0
133
1010
1.35
2.64
3.5
3.9
1.2
1.2
mmol/l
0.36
120
872
50
313
1.62
2.64
2.1
1.6
278.5
284.9
mu/l
0.07
43
282
16
67
2.40
2.63
1.7
1.2
—
—
—
0
0
16
67
2.40
2.63
1.7
1.2
—
—
—
0
0
47
291
1.64
2.59
1.6
1.3
—
—
—
0
0
52
331
1.59
2.57
1.8
2.1
10.5
11.9
mg/l
0.75
47
304
6
11
5.47
2.54
1.2
1.0
—
—
—
0
0
1235
11872
1.25
2.53
4.7
4.5
4.5
4.6
mmol/l
2.12
1160
10946
45
278
1.64
2.51
1.2
1.4
10.4
9.1
u/l
0.22
35
225
1226
11783
1.24
2.47
4.6
4.4
1.4
1.4
mmol/l
3.84
1143
10788
31
174
1.80
2.43
1.1
1.1
1.5
1.9
u/ml
0.12
17
77
416
3658
1.19
2.35
3.0
3.0
1199.7
1394.8
ng/l
0.63
366
3129
47
300
1.59
2.32
1.1
1.2
—
—
—
0
0
45
287
1.59
2.24
1.2
1.1
—
—
—
0
0
127
985
1.32
2.22
2.2
2.3
12.7
13.0
nmol/l
0.18
113
873
5
9
5.57
2.21
1.4
1.1
—
—
—
0
0
334
2895
1.20
2.20
1.6
1.6
19.8
20.5
nmol/l
0.39
298
2460
89
655
1.38
2.19
2.6
3.4
4.3
4.5
pmol/l
1.16
79
572
73
520
1.42
2.17
2.1
2.0
36.5
39.2
u/l
0.65
64
461
81
588
1.40
2.16
2.0
1.8
1.6
1.6
g/l
0.29
68
514
7
19
3.70
2.15
1.0
1.3
—
—
—
0
0
1251
12097
1.22
2.09
5.3
5.0
2.7
2.7
mmol/l
1.94
1172
11078
123
964
1.30
2.01
1.9
1.9
—
—
—
0
0
29
170
1.72
2.01
1.1
1.1
—
—
—
0
0
123
966
1.30
1.99
3.0
2.7
67.1
64.7
ml/min/173m2
0.24
53
400
28
164
1.72
1.95
1.0
1.1
—
—
—
0
0
38
242
1.59
1.94
2.9
3.6
58.0
57.4
%
0.14
38
242
1182
11396
1.19
1.89
4.1
4.0
1.4
1.3
mmol/l
2.60
1088
10377
63
450
1.42
1.88
2.7
2.5
10.6
10.6
g/l
0.01
53
385
11
46
2.40
1.85
1.1
1.8
—
—
—
0
0
19
102
1.87
1.76
1.4
1.1
134.0
145.3
titre
—
5
17
14
67
2.10
1.76
1.9
2.0
—
—
—
0
0
18
95
1.91
1.75
2.4
1.5
—
—
—
0
0
36
233
1.56
1.74
2.9
3.3
4.2
4.4
e9/l
0.18
36
233
62
449
1.40
1.73
2.5
2.7
—
—
—
0
0
129
1041
1.26
1.71
2.6
2.8
64.9
66.5
g/l
1.86
119
949
31
195
1.60
1.69
1.3
1.3
—
—
—
0
0
137
1117
1.25
1.67
6.9
7.6
10.0
9.9
mmol/l
0.06
131
1072
135
1106
1.24
1.59
2.0
2.5
7.9
7.2
ug/l
0.13
120
989
7
26
2.70
1.58
1.0
1.0
—
—
—
0
0
35
231
1.53
1.58
1.3
1.2
57.7
48.3
u/ml
—
5
17
108
864
1.27
1.56
1.9
1.9
—
—
—
0
0
49
348
1.42
1.55
1.6
1.5
262.8
286.1
ug/g
0.37
34
200
40
273
1.48
1.55
2.2
2.6
15.5
16.2
%
0.26
13
143
221
1907
1.19
1.54
1.3
1.2
8.2
11.5
u/ml
0.39
71
734
38
257
1.49
1.54
4.3
5.4
432.0
223.5
iu/ml
—
5
31
49
349
1.42
1.53
1.5
1.2
—
—
—
0
0
61
452
1.36
1.52
2.9
2.5
3.0
3.1
g/l
0.48
51
358
264
2319
1.17
1.49
1.9
1.8
1093.7
1186.3
nmol/l
1.03
210
1734
125
1515
0.81
1.49
4.4
4.5
30.9
32.1
%
0.57
96
1012
23
139
1.67
1.48
1.3
1.4
188.2
297.5
pmol/l
2.23
18
111
47
335
1.42
1.47
2.8
2.3
185.9
191.9
%
0.16
42
317
43
302
1.44
1.46
1.4
1.6
35601.8
16997.5
e6/l
0.63
22
219
140
1164
1.22
1.45
2.5
2.2
0.2
0.2
g/l
2.12
133
1092
115
936
1.25
1.45
4.4
3.8
93.3
89.9
ng/l
0.14
102
824
64
482
1.34
1.45
2.8
2.5
3.4
3.8
g/l
1.80
51
351
6
22
2.73
1.43
1.0
1.0
116.2
30.1
u/ml
—
6
22
64
483
1.34
1.43
2.8
2.5
7.1
7.4
g/l
0.45
51
367
64
483
1.34
1.43
2.8
2.5
—
—
—
0
0
45
322
1.41
1.39
1.6
1.5
—
—
—
0
0
50
366
1.38
1.36
2.5
2.1
89.4
90.2
%
0.07
45
349
16
90
1.79
1.33
1.4
1.5
—
—
—
0
0
276
2455
1.15
1.33
1.3
1.2
1.3
1.6
u/ml
0.29
69
642
515
4770
1.12
1.33
4.2
3.7
160.3
49.6
ng/l
0.42
351
3423
39
276
1.42
1.29
1.6
1.9
2.9
5.3
iu/l
2.30
15
93
54
405
1.35
1.28
3.7
3.6
36.1
71.2
mg/l
0.57
40
329
92
743
1.25
1.27
1.9
1.6
—
—
—
0
0
46
337
1.38
1.26
1.3
1.4
—
—
—
0
0
348
3163
1.13
1.22
4.8
4.0
0.0
0.0
estimate
0.69
129
1083
37
263
1.42
1.21
1.5
2.3
133.7
129.4
g/l
0.42
24
203
174
1507
1.18
1.19
1.4
1.4
—
—
—
0
0
54
411
1.33
1.18
3.5
2.7
1.0
1.3
g/l
0.48
47
364
422
3889
1.12
1.17
3.3
3.2
7.2
7.7
mmol/l
1.51
362
3260
32
223
1.44
1.17
1.3
1.5
—
—
—
0
0
56
430
1.31
1.16
1.8
1.7
2.4
4.2
mg/l
0.73
45
311
53
404
1.32
1.15
3.8
3.6
42.6
66.2
mg/l
0.76
39
327
15
87
1.73
1.15
2.2
1.5
1.0
1.0
g/l
0.02
15
87
13
73
1.79
1.11
2.1
2.0
13.4
16.2
%
—
8
29
13
74
1.76
1.07
1.5
1.6
—
—
—
0
0
26
178
1.47
1.05
1.3
1.5
—
—
—
0
0
26
179
1.46
1.03
1.3
1.5
—
—
—
0
0
10
53
1.89
1.01
1.0
1.2
151.6
227.5
iu/ml
—
10
53
19
123
1.55
0.99
3.7
2.3
—
—
—
0
0
17
261
0.65
0.99
5.9
3.8
25.9
27.0
mg/l
—
10
170
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
48
371
1.30
0.98
1.6
1.9
—
—
—
0
0
23
157
1.47
0.96
1.3
1.0
1.2
2.3
u/ml
1.27
14
63
95
798
1.20
0.96
6.6
7.7
24.9
24.5
mmol/l
0.52
87
747
418
3892
1.10
0.95
4.3
4.0
6.5
8.9
mg/mmol
0.90
277
2487
172
1520
1.15
0.94
10.1
7.4
—
—
—
0
0
41
312
1.32
0.94
1.2
1.1
0.7
7.6
u/ml
—
9
29
10
55
1.82
0.92
4.3
3.8
—
—
—
0
0
6
29
2.07
0.89
1.2
1.2
—
—
—
0
0
8
42
1.91
0.88
2.6
1.9
136.0
53.8
ug/l
—
8
42
10
56
1.79
0.88
1.1
1.2
—
—
—
0
0
220
1990
1.12
0.86
1.3
1.3
22.8
32.6
iu/ml
1.23
57
635
27
198
1.37
0.80
1.3
1.5
—
—
—
0
0
23
164
1.41
0.80
1.2
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
2.0
—
1.0
—
0
16
12
74
1.63
0.78
1.5
1.6
—
—
—
0
0
5
98
0.51
0.78
2.0
1.5
—
—
—
0
0
39
305
1.29
0.77
1.4
1.2
19.1
8.8
u/ml
—
5
47
10
59
1.70
0.76
2.2
2.9
1037.3
1478.6
u/ml
—
10
59
21
150
1.41
0.73
1.5
1.5
81.7
62.4
%
1.92
13
101
63
525
1.21
0.73
2.1
2.0
6.0
1.8
ug/l
0.75
58
465
38
299
1.28
0.72
1.4
1.2
1.8
2.5
u/ml
—
5
28
20
142
1.41
0.72
1.8
1.7
—
—
—
0
0
241
2615
0.91
0.71
1.8
1.7
66019853.9
28798190.3
pmol/l
0.36
206
2146
9
57
1.58
0.71
1.0
1.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.1
47.8
34.1
nmol/l
—
5
21
54
446
1.22
0.69
2.1
1.9
—
—
—
0
0
29
222
1.31
0.68
1.5
1.3
111.6
127.8
u/ml
—
7
38
7
118
0.59
0.68
1.3
1.4
1.2
1.4
nmol/l
—
7
106
15
102
1.48
0.67
1.2
1.3
—
—
—
0
0
21
153
1.38
0.67
1.4
1.5
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
8
130
0.61
0.63
1.0
1.1
—
—
—
0
0
21
155
1.36
0.63
1.4
1.5
—
—
—
0
0
21
155
1.36
0.63
1.4
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
55
464
1.19
0.59
1.9
2.3
910.8
446.9
ug/l
0.42
49
441
274
2562
1.09
0.59
5.1
4.0
1.0
1.0
kg/l
1.56
38
377
158
1441
1.11
0.57
1.6
1.8
1.5
1.5
%
0.11
128
1246
25
194
1.29
0.56
3.2
3.7
0.8
1.5
%
0.89
15
160
9
61
1.48
0.53
2.3
2.0
—
—
—
0
0
21
160
1.32
0.53
1.8
1.6
—
—
—
0
0
20
152
1.32
0.52
1.5
1.5
—
—
—
0
0
20
152
1.32
0.52
1.5
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
426
1.18
0.50
2.2
2.6
0.3
0.3
u/ml
0.42
23
238
9
65
1.39
0.50
1.0
1.0
—
—
—
0
0
20
153
1.31
0.50
1.5
1.5
—
—
—
0
0
10
67
1.50
0.49
1.7
1.9
—
—
—
0
0
10
67
1.50
0.49
1.7
1.9
—
—
—
0
0
10
67
1.50
0.49
1.7
1.9
—
—
—
0
0
10
67
1.50
0.49
1.7
1.9
—
—
—
0
0
42
353
1.20
0.49
2.0
1.8
—
—
—
0
0
21
268
0.78
0.49
5.0
3.3
8.2
7.5
mmol/l
0.55
21
262
486
4670
1.06
0.49
5.0
4.8
2.4
2.7
ug/l
0.45
431
4183
392
3744
1.06
0.48
4.1
4.2
23.2
21.4
%
1.42
182
1788
38
318
1.20
0.47
1.7
2.4
114.4
93.8
ug/min
0.18
18
191
32
263
1.22
0.47
1.2
2.0
0.9
0.8
nmol/l
0.07
26
220
468
4500
1.06
0.46
4.7
3.9
—
—
—
0
0
37
310
1.20
0.46
1.6
1.7
—
—
—
0
0
60
525
1.15
0.45
5.2
6.3
1.8
1.6
%
0.54
54
493
13
95
1.37
0.43
1.0
1.1
—
43.4
—
0
5
23
285
0.80
0.43
1.5
1.5
—
—
—
0
0
10
140
0.71
0.43
1.0
1.1
—
—
—
0
0
13
96
1.36
0.41
1.0
1.1
—
61.9
—
0
8
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.7
—
0
11
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
5
35
1.43
0.39
1.0
1.3
—
—
—
0
0
10
71
1.41
0.39
2.1
1.6
0.9
5.3
u/field
—
10
52
9
68
1.33
0.37
1.2
1.3
—
69.0
—
0
10
91
996
0.91
0.37
1.6
1.8
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
211.2
294.0
pmol/l
—
5
24
9
71
1.27
0.36
1.3
1.3
—
—
—
0
0
27
226
1.20
0.36
1.8
1.8
—
—
—
0
0
5
76
0.66
0.35
1.0
1.1
—
—
—
0
0
32
273
1.18
0.35
1.5
1.4
32.1
41.8
e6/l
0.13
25
211
32
273
1.18
0.35
1.5
1.5
21461.0
836.9
e6/l
0.53
26
220
31
265
1.17
0.33
2.0
1.9
204.5
217.0
pmol/l
0.23
31
249
13
100
1.30
0.33
1.1
1.1
—
—
—
0
0
42
369
1.14
0.33
1.5
1.6
0.5
19.8
iu/ml
—
8
61
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
33
286
1.16
0.31
2.7
3.2
30.2
34.6
umol/l
0.66
26
237
282
2708
1.05
0.31
3.0
3.0
0.8
0.7
ug/l
0.57
188
1782
79
729
1.09
0.28
1.1
1.2
73.9
139.7
iu/ml
1.81
33
287
5
73
0.68
0.26
43.0
19.6
1570.0
1492.6
nmol/l
—
5
73
15
123
1.22
0.25
1.9
1.6
—
—
—
0
0
18
152
1.19
0.23
1.7
1.4
625.4
1617.6
e6/l
3.07
11
106
30
267
1.13
0.21
1.3
1.4
—
—
—
0
0
13
107
1.22
0.21
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
15
177
0.85
0.21
1.4
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
0.0
—
0
6
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
95.3
—
0
14
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
16
136
1.18
0.20
1.8
1.4
44158.6
73498.7
e6/l
—
7
79
77
819
0.94
0.20
4.2
3.6
5.1
5.1
kpa
0.05
72
766
9
115
0.78
0.20
1.1
1.0
—
—
—
0
0
17
197
0.86
0.19
1.2
1.1
—
—
—
0
0
54
582
0.93
0.19
5.4
3.7
51.6
49.0
%
0.33
54
574
33
298
1.11
0.19
1.7
1.7
—
—
—
0
0
6
52
1.15
0.19
1.8
2.1
—
—
—
0
0
6
52
1.15
0.19
1.8
2.1
—
—
—
0
0
6
53
1.13
0.18
1.8
2.1
—
—
—
0
0
15
128
1.17
0.18
4.9
2.8
—
—
—
0
0
16
184
0.87
0.17
1.3
1.2
2.0
4.5
u/ml
—
5
57
10
82
1.22
0.17
1.4
1.1
—
—
—
0
0
10
82
1.22
0.17
1.4
1.1
—
—
—
0
0
21
186
1.13
0.17
1.8
1.5
—
—
—
0
0
57
534
1.07
0.16
1.1
1.0
—
—
—
0
0
8
70
1.14
0.16
1.1
1.6
—
—
—
0
0
10
83
1.21
0.15
1.4
1.1
—
—
—
0
0
10
83
1.21
0.15
1.4
1.1
—
—
—
0
0
10
83
1.21
0.15
1.4
1.1
—
—
—
0
0
9
78
1.15
0.15
1.2
1.3
3.1
2.5
ug/l
—
9
62
29
265
1.10
0.14
2.5
3.1
0.9
0.8
nmol/l
0.07
24
208
7
89
0.79
0.14
1.0
1.0
—
—
—
0
0
7
90
0.78
0.14
1.3
1.3
13.3
13.8
u/l
—
7
84
41
382
1.08
0.14
1.9
1.8
—
—
—
0
0
32
345
0.93
0.13
3.4
2.8
24.8
24.8
mmol/l
0.03
27
302
33
306
1.08
0.13
1.3
1.3
—
—
—
0
0
10
85
1.18
0.12
1.0
1.2
—
—
—
0
0
132
1286
1.03
0.10
3.6
4.3
67.2
23.0
ug/l
0.33
106
1060
21
193
1.09
0.10
1.6
1.6
—
—
—
0
0
16
176
0.91
0.09
1.1
1.1
—
—
—
0
0
13
116
1.12
0.09
1.3
1.5
0.3
0.3
nmol/l
—
8
90
25
233
1.07
0.09
1.1
1.2
189.5
275.7
u/ml
1.01
13
140
12
134
0.89
0.08
1.3
1.6
—
—
—
0
0
6
58
1.03
0.08
2.5
1.4
—
—
—
0
0
6
58
1.03
0.08
2.5
1.4
—
—
—
0
0
5
62
0.81
0.08
6.0
3.2
—
—
—
0
0
13
117
1.11
0.08
1.6
1.7
—
—
—
0
0
47
455
1.03
0.05
1.9
1.8
—
—
—
0
0
12
110
1.09
0.05
1.7
1.6
—
—
—
0
0
26
248
1.05
0.05
1.1
1.2
—
—
—
0
0
76
776
0.98
0.04
3.6
3.5
1.6
1.8
mmol/l
0.22
51
575
27
281
0.96
0.04
1.5
1.4
—
—
—
0
0
24
230
1.04
0.03
1.8
2.3
3616.4
3376.4
u/l
—
7
94
12
128
0.94
0.02
1.0
1.1
—
—
—
0
0
13
123
1.06
0.01
1.5
1.8
—
—
—
0
0
49
483
1.01
0.01
3.3
3.4
12632.4
3087.4
u/ml
0.34
42
408
11
104
1.06
0.01
1.2
1.2
—
—
—
0
0
12
116
1.03
0.00
1.6
1.7
—
—
—
0
0
12
116
1.03
0.00
1.6
1.7
—
—
—
0
0
12
116
1.03
0.00
1.6
1.7
—
—
—
0
0
14
136
1.03
0.00
1.4
1.8
—
—
—
0
0
49
494
0.99
0.00
4.4
4.0
24.6
24.9
mmol/l
0.27
44
465
15
152
0.99
0.00
1.3
1.4
—
—
—
0
0
15
152
0.99
0.00
1.3
1.4
—
—
—
0
0
15
152
0.99
0.00
1.3
1.4
—
—
—
0
0
15
152
0.99
0.00
1.3
1.4
—
—
—
0
0
29
292
0.99
0.00
1.5
1.3
241.6
227.5
miu/ml
0.07
14
131
18
183
0.98
0.00
1.3
1.2
2.1
6.4
u/ml
—
8
79
49
493
0.99
0.00
2.2
1.9
—
—
—
0
0
17
165
1.03
0.00
1.2
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
38.9
—
0
8
0
8
0.00
0.00
0.0
1.0
—
21.3
—
0
8
7
69
1.01
0.00
2.3
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
7.5
—
0
8
7
69
1.01
0.00
2.3
1.4
—
—
—
0
0
6
69
0.87
0.00
1.2
6.5
—
69.3
—
0
18
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
7.5
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
2.2
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
4.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_EAR_NASAL_SINUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EAR_NASAL_SINUS | 1.289 [1.13, 1.47] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.221 |
During the follow-up period (1.1.1998 — 31.12.2019), 531 out of 3276 females with CD2_BENIGN_EAR_NASAL_SINUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EAR_NASAL_SINUS | 1.197 [0.99, 1.44] | 0.058 |
| Birth year | 0.989 [0.94, 1.04] | 0.691 |
During the follow-up period (1.1.1998 — 31.12.2019), 689 out of 3623 males with CD2_BENIGN_EAR_NASAL_SINUS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_EAR_NASAL_SINUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.216% |
| 5 | 0.85% | 1.352% |
| 10 | 2.003% | 3.63% |
| 15 | 3.69% | 6.902% |
| 20 | 6.21% | 11.55% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_EAR_NASAL_SINUS – Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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