Vascular dementia

F5_VASCDEM

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F01
  • Hospital discharge: ICD-9 4378
  • Cause of death: ICD-10 F01
  • Cause of death: ICD-9 4378

2 out of 7 registries used, show all original rules.

4362

4. Check minimum number of events

None

4362

5. Include endpoints

None

4362

6. Filter based on genotype QC (FinnGen only)

4254

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F00-F03
Name in latin
Dementia vascularis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 65659 37270 27252
Only index persons 40397 23852 16545
Unadjusted period prevalence (%)
Whole population 0.94 1.07 0.76
Only index persons 0.78 0.88 0.63
Median age at first event (years)
Whole population 82.41 84.09 80.27
Only index persons 83.66 85.41 81.13

-FinnGen-

Key figures

All Female Male
Number of individuals 4254 1670 2584
Unadjusted period prevalence (%) 0.95 0.59 1.18
Median age at first event (years) 81.60 83.29 80.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4359
Matched controls
42027
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F01
ICD-10 Finland
Vascular dementia
85.2
307.7
258
31
P20
ICPC
Memory disturbance
5.4
307.7
1491
3702
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
307.7
353
*
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
205.2
307.7
203
10
G30.1
ICD-10 Finland
Alzheimer disease with late onset
26.9
307.7
714
304
F01.9
ICD-10 Finland
Vascular dementia, unspecified
542.8
307.7
1991
65
F03
ICD-10 Finland
Unspecified dementia
49.4
307.7
985
247
N06DA02
ATC
donepezil; oral
67.4
307.7
680
115
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
440.0
307.7
339
8
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
52.6
307.7
223
43
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
242.2
307.7
697
33
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
40.6
307.7
228
57
P70
ICPC
Dementia
16.8
307.7
327
202
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
4.9
307.7
1265
3249
N05AH04
ATC
quetiapine; oral
5.8
307.7
1009
2085
N06DA03
ATC
rivastigmine; oral, transdermal
74.0
307.7
473
69
N06DX01
ATC
memantine; oral
90.3
307.7
1081
153
G30.8
ICD-10 Finland
Other Alzheimer disease
31.3
307.7
297
98
N06DA04
ATC
galantamine; oral
110.3
307.7
367
35
N05AX08
ATC
risperidone; systemic
12.3
307.7
1171
1221
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
6.9
307.7
1124
2028
F01.2
ICD-10 Finland
Subcortical vascular dementia
240.6
307.7
468
21
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
19.9
307.7
333
174
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
190.2
307.7
362
20
R53
ICD-10 Finland
Malaise and fatigue
3.2
282.9
1678
6850
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
271.2
261
*
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
539.6
264.5
264
5
R41.0
ICD-10 Finland
Disorientation, unspecified
6.2
262.9
487
833
A28
ICPC
Limited function/disability NOS
3.1
260.0
1661
7014
F05.1
ICD-10 Finland
Delirium superimposed on dementia
36.7
257.3
165
45
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.3
253.1
1325
4974
SPAT1053
SPAT
Memory test
3.2
234.8
1284
4917
F01.1
ICD-10 Finland
Multi-infarct dementia
+∞
218.7
211
*
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
9.7
210.2
255
267
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.6
207.8
2071
10746
F01.0
ICD-10 Finland
Vascular dementia of acute onset
689.6
206.4
205
*
AA1AD
NOMESCO Finland
CT of head and brain
2.5
181.4
1752
8815
R41.3
ICD-10 Finland
Other amnesia
6.1
180.2
330
554
N03AG01
ATC
valproic acid; systemic, rectal
5.9
174.8
336
591
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
161.2
1528
7537
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.1
146.8
713
2486
F05.9
ICD-10 Finland
Delirium, unspecified
5.5
143.5
290
533
N05AH03
ATC
olanzapine; systemic
5.9
132.4
251
434
F01.39
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without information on additional symptoms
1293.0
132.2
130
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.8
130.9
431
1170
N06AX11
ATC
mirtazapine; oral
2.3
130.4
1487
7808
L28
ICPC
Limited function/disability (L)
2.3
126.4
1249
6161
N05BA04
ATC
oxazepam; oral
2.3
123.4
1307
6629
N06AB04
ATC
citalopram; systemic
2.4
123.1
1043
4799
SPAT1216
SPAT
Assessment of functional ability
2.4
121.1
1091
5156
G30
ICD-10 Finland
Alzheimer disease
32.3
119.0
79
24
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
112.7
1109
5423
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
111.2
1934
11780
N05AD01
ATC
haloperidol; systemic
4.2
108.2
310
759
F01.8
ICD-10 Finland
Other vascular dementia
161.2
107.2
114
7
F01.24
ICD-10 Finland
Subcortical vascular dementia other additional symptoms of mixed type
270.4
105.8
109
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
105.3
730
3038
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.4
102.6
409
1254
F06.7
ICD-10 Finland
Mild cognitive disorder
4.4
102.0
273
634
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
101.8
1030
5067
N06AB10
ATC
escitalopram; oral
2.7
99.4
615
2414
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.7
98.3
608
2386
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
98.2
979
4779
WYA20
NOMESCO Finland
Home visit
5.6
94.8
185
328
XA800
NOMESCO Finland
Neuropsychological investigation
6.3
90.6
158
251
A06AD11
ATC
lactulose; oral
2.0
88.3
1229
6786
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
84.6
672
2958
N06AX26
ATC
vortioxetine; oral
4.3
83.7
229
540
S01.0
ICD-10 Finland
Open wound of scalp
2.7
82.6
500
1932
F01.34
ICD-10 Finland
Mixed cortical and subcortical vascular dementia are other mixed symptoms of mixed type
273.1
80.7
83
*
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
139.3
79.0
85
6
N02AA05
ATC
oxycodone; systemic
2.0
77.4
1124
6255
N30.0
ICD-10 Finland
Acute cystitis
2.2
77.1
814
4026
N05AD03
ATC
melperone; systemic
5.1
74.8
163
319
F01.80
ICD-10 Finland
Other specified vascular dementia without additional symptoms
155.1
74.1
79
5
A04
ICPC
Weakness/tiredness general
2.1
72.8
806
4051
SPAT1254
SPAT
Administration of medicine
2.1
72.1
890
4658
S06.0
ICD-10 Finland
Concussion
2.5
71.4
525
2222
N02BE01
ATC
paracetamol; systemic, rectal
2.0
71.3
3456
27677
W19
ICD-10 Finland
Unspecified fall
2.4
70.9
558
2435
I95.1
ICD-10 Finland
Orthostatic hypotension
2.9
70.8
362
1277
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.9
70.7
367
1305
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
5.5
68.6
135
241
S72.0
ICD-10 Finland
Fracture of neck of femur
2.6
66.4
438
1759
R55
ICD-10 Finland
Syncope and collapse
2.1
65.3
732
3684
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.3
65.2
260
793
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.4
65.1
520
2279
G30.0
ICD-10 Finland
Alzheimer disease with early onset
23.4
64.8
48
20
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.0
64.8
304
1021
SPAT1234
SPAT
Support of social functional capacity
2.7
64.7
386
1475
K90
ICPC
Stroke/cerebrovascular accident
3.2
62.3
256
795
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
61.4
914
5077
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
60.7
208
575
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.5
59.8
407
1656
Z75.5
ICD-10 Finland
Holiday relief care
5.0
58.7
130
258
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
88.1
56.1
63
7
N05BA06
ATC
lorazepam; systemic, sublingual
2.7
55.4
329
1252
F21, ,
ICPC
5.6
55.3
107
188
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.8
55.2
290
1035
F01.23
ICD-10 Finland
Subcortical vascular dementia other additional symptoms, mainly depression
144.1
55.1
59
*
R42
ICD-10 Finland
Dizziness and giddiness
1.8
54.6
1199
7470
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
54.4
714
3785
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
53.9
479
2190
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
4.5
52.5
133
295
4378A
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Other[MULTI-INFARKTIDEMENTIA]
+∞
51.5
50
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.8
50.2
262
931
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
50.1
2969
23662
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
49.0
859
4985
N30.9
ICD-10 Finland
Cystitis, unspecified
2.4
48.4
372
1596
F05.8
ICD-10 Finland
Other delirium
6.1
48.4
85
136
F0019, G301,
ICD-10 Finland
+∞
48.4
47
*
F01.14
ICD-10 Finland
Multi-infarct dementia's other mixed symptoms of mixed type
+∞
48.4
47
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
48.1
772
4357
F01.21
ICD-10 Finland
Subcortical vascular dementia without additional symptoms, mainly paranoidism
126.8
48.1
52
*
S70.0
ICD-10 Finland
Contusion of hip
2.7
48.1
279
1048
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.3
47.7
127
293
E86
ICD-10 Finland
Volume depletion
3.0
47.2
222
745
F01.22
ICD-10 Finland
Subcortical vascular dementia with additional symptoms, mainly hallucinations
155.9
45.2
48
*
F01.89
ICD-10 Finland
Other specified vascular dementia without information on additional symptoms
436.3
44.7
45
*
SPAT1360
SPAT
Extensive global examination
2.3
44.5
356
1552
OAB41
NOMESCO Finland
Guidance and counselling related to ageing
16.8
44.5
38
22
K91
ICPC
Cerebrovascular disease
4.1
43.5
123
297
U04
ICPC
Incontinence urine
2.3
43.4
335
1438
SPAT1229
SPAT
Assessment of need for aid
2.1
43.4
476
2354
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.1
43.3
191
618
F01.84
ICD-10 Finland
Other specified vascular dementia other mixed symptoms of mixed type
149.4
43.2
46
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
41.9
269
1061
130
Kela drug reimbursment
Malignant tumour
0.2
41.6
81
3086
J01DB01
ATC
cefalexin; oral
1.6
41.2
2879
23252
Z2445
NOMESCO Finland
Psychologist
4.9
40.9
92
185
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.1
40.7
175
558
TAB00
NOMESCO Finland
Lumbar puncture
3.6
40.1
134
364
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
10.2
39.3
45
43
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
39.2
615
3428
F22.0
ICD-10 Finland
Delusional disorder
5.1
39.2
84
162
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.2
39.2
82
155
A10AB05
ATC
insulin aspart; parenteral
2.1
39.0
379
1787
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
38.8
318
1399
J01CA08
ATC
pivmecillinam; oral
1.6
38.7
1444
10117
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.1
38.3
106
252
4378X
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Other[MORBUS CERBROVASCULARIS ALIA DEFINITA]
+∞
38.1
37
*
F009, G309,
ICD-10 Finland
+∞
38.1
37
*
C10AA01
ATC
simvastatin; oral
1.5
37.4
2255
17468
B01AC07
ATC
dipyridamole; systemic
1.9
36.9
547
2992
F01.33
ICD-10 Finland
Mixed cortical and subcortical vascular dementia other additional symptoms, mainly depression
357.3
36.5
37
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.5
35.5
244
993
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.0
35.3
101
246
SPAT1301
SPAT
No procedures
1.5
35.0
1294
9003
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
76.0
34.3
39
5
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
34.2
554
3111
N03AF02
ATC
oxcarbazepine; oral
3.1
33.6
142
448
SPAT1172
SPAT
Guidance concerning hydration
2.6
33.6
195
732
N06AB06
ATC
sertraline; oral
2.3
33.5
272
1191
A10AE04
ATC
insulin glargine; parenteral
1.9
32.9
451
2402
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
32.5
1305
9213
Z02.7
ICD-10 Finland
Issue of medical certificate
2.1
32.0
310
1458
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
31.9
31
*
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
10.3
31.7
36
34
B01AC04
ATC
clopidogrel; oral
1.6
31.4
990
6616
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
30.9
417
2208
F01.32
ICD-10 Finland
Mixed cortical and subcortical vascular dementia other additional symptoms, mainly hallucinations
+∞
30.8
30
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
30.8
599
3541
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
30.5
198
785
Y94.0
ICD-10 Finland
Accident at home
3.2
30.5
121
368
OAB76
NOMESCO Finland
General guidance on nutrition and food
67.9
30.4
35
5
AXX01
NOMESCO Finland
Memory assessment
34.5
30.0
39
11
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
29.9
302
1442
SPAT1167
SPAT
Insertion of urinary catheter
2.3
29.9
238
1033
J01EA01
ATC
trimethoprim; systemic
1.5
29.4
1209
8542
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.3
29.4
236
1028
IHZ08
NOMESCO Finland
Provision of support and information for patient’s relatives
43.7
29.1
36
8
R4110
NOMESCO Finland
Physiotherapy
1.5
29.0
1036
7105
N05AX12
ATC
aripiprazole; systemic
6.1
28.9
51
82
R33
ICD-10 Finland
Retention of urine
1.7
28.4
564
3351
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
5.5
28.1
55
98
R1250
NOMESCO Finland
Evaluation of functional capability
3.8
28.1
87
225
A29
ICPC
General symptom/complaint other
1.7
27.5
549
3263
F01.31
ICD-10 Finland
Mixed cortical and subcortical vascular dementia other additional symptoms, mainly paranoidism
273.1
27.4
28
*
W0A10
NOMESCO Finland
Mapping of psychosocial situation
31.8
27.2
36
11
SPAT1262
SPAT
Handing over of treatment supplies
1.6
27.2
727
4656
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.0
27.0
59
116
Z3226
NOMESCO Finland
Physiotherapist
1.6
26.9
746
4820
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
26.7
26
*
WX212
NOMESCO Finland
Femoral plexus blockade
2.7
26.7
144
521
R44.3
ICD-10 Finland
Hallucinations, unspecified
6.8
26.7
42
60
ZXD35
NOMESCO Finland
Usual procedure
2.5
26.4
168
659
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.7
26.3
143
519
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
26.2
604
3726
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.3
26.1
98
288
I67.2
ICD-10 Finland
Cerebral atherosclerosis
4.9
26.0
58
116
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
5.5
25.4
49
86
N06AX21
ATC
duloxetine; oral
1.9
25.4
315
1618
J01MA02
ATC
ciprofloxacin; systemic
1.4
25.3
1707
13157
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
3.8
25.1
77
198
C03CA01
ATC
furosemide; systemic
1.4
25.0
2302
18701
Z3231
NOMESCO Finland
Registered nurse
1.5
24.9
1118
7993
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.5
24.9
877
5970
N06AX16
ATC
venlafaxine; oral
2.0
24.8
276
1365
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
3.7
24.6
78
205
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.1
24.4
230
1070
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.8
24.3
74
189
W06
ICD-10 Finland
Fall involving bed
3.8
24.2
74
190
R32
ICD-10 Finland
Unspecified urinary incontinence
2.5
24.1
150
583
R4120
NOMESCO Finland
Occupational therapy
2.1
24.0
234
1102
F01.11
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly paranoidism
+∞
23.6
23
*
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.2
23.6
209
948
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
23.5
882
6074
N05AB03
ATC
perphenazine; systemic, rectal
2.9
23.5
113
385
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.5
23.2
151
599
F01.81
ICD-10 Finland
Other specified vascular dementia has other additional symptoms, mainly paranoidism
121.2
23.2
25
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
22.8
639
4126
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.3
22.8
85
249
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
22.8
395
2253
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
52.4
22.7
27
5
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
22.4
125
460
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
2.6
22.3
131
495
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
6.6
22.2
36
53
C07AB07
ATC
bisoprolol; oral
1.4
22.2
2427
20101
F00
ICD-10 Finland
Dementia in Alzheimer disease
18.3
22.1
34
18
N18
ICPC
Paralysis/weakness
2.8
21.9
114
405
EBA30
NOMESCO Finland
Extraction of root of tooth
2.1
21.9
222
1062
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.0
21.9
245
1215
C09AA05
ATC
ramipril; oral
1.4
21.8
1336
10061
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.9
21.6
292
1542
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
21.6
617
3999
P29
ICPC
Psychological sympt/compl other
2.9
21.5
103
350
SPAT1252
SPAT
Overall medication plan or its review
1.8
21.5
341
1895
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
21.4
617
8528
SPAT1101
SPAT
Orthostatic test
1.9
21.4
269
1388
R44.1
ICD-10 Finland
Visual hallucinations
5.3
21.3
43
79
ZXD05
NOMESCO Finland
Urgent procedure
1.4
21.2
1240
9254
N28
ICPC
Limited function/disability (N)
3.2
21.2
84
256
H02AB02
ATC
dexamethasone; systemic
0.4
21.2
100
2429
S06.3
ICD-10 Finland
Focal brain injury
3.5
21.1
73
204
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
20.8
1458
11214
N03AX14
ATC
levetiracetam; systemic
2.8
20.6
107
380
F0009, G300,
ICD-10 Finland
+∞
20.6
20
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
20.5
145
598
N29
ICPC
Neurological sympt/complt other
3.2
20.5
82
251
SPAT1231
SPAT
Assessment of adjustments needed in living environment
2.5
20.5
130
510
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
20.5
1615
12647
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.9
20.5
259
1339
C08CA01
ATC
amlodipine; oral
1.4
20.4
1776
14125
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
4.2
20.3
54
125
SPAT1139
SPAT
Nutrition survey
2.3
20.2
157
675
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
20.2
291
1569
WYA20, ,
SPAT
5.3
19.9
40
73
EBA00
NOMESCO Finland
Extraction of tooth
1.4
19.9
923
6601
P99
ICPC
Psychological disorders other
4.3
19.9
51
115
A10BA02
ATC
metformin; oral
1.4
19.8
1296
9839
B01AA03
ATC
warfarin; systemic
1.4
19.7
1445
11172
N05CD07
ATC
temazepam; oral
1.5
19.6
764
5281
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
19.5
860
6085
E000001, ,
ATC
1.5
19.5
673
4536
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
19.5
19
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.9
19.5
58
146
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
4.1
19.5
53
125
F10.24
ICD-10 Finland
Alcohol depence active use
5.9
19.3
35
58
SPAT1279
SPAT
Preparation of immediate hospitalisation
2.8
19.3
94
323
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.4
19.3
139
579
A01
ICPC
Pain general/multiple sites
1.7
19.3
344
1977
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.2
19.1
75
227
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.1
19.1
177
818
G04BD12
ATC
mirabegron; oral
1.6
18.8
487
3078
G04CA02
ATC
tamsulosin; oral
1.4
18.7
1383
10683
F0029, G308,
ICD-10 Finland
+∞
18.5
18
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
1.9
18.5
230
1183
R54
ICD-10 Finland
Senility
3.4
18.0
64
182
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.1
18.0
183
876
S01
ICD-10 Finland
Open wound of head
3.4
17.8
64
184
E0000UV, ,
ATC
1.4
17.7
1314
10136
Z2221
NOMESCO Finland
Medical doctor
1.4
17.7
975
7170
SPAT1255
SPAT
Intravenous administration of medicine
1.8
17.6
278
1541
F0014, G301,
ICD-10 Finland
+∞
17.5
17
*
ZXA05
NOMESCO Finland
Left side
1.4
17.5
1100
8266
A98
ICPC
Health maint/preventive medicine
1.3
17.5
2900
25111
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.3
17.4
65
191
G04BD07
ATC
tolterodine; oral
1.8
17.4
297
1684
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
17.3
108
421
R11
ICD-10 Finland
Nausea and vomiting
1.7
17.3
359
2147
R5110, ,
SPAT
1.8
17.3
277
1542
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
3.3
17.3
66
197
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
2.5
17.2
108
422
C10AA05
ATC
atorvastatin; oral
1.3
17.1
1653
13246
A10AE05
ATC
insulin detemir; parenteral
1.9
17.0
219
1139
SPAT1138
SPAT
Guidance concerning bowel function
2.7
16.9
91
330
SPAT1165
SPAT
Peritoneal dialysis
7.5
16.6
24
31
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
5.7
16.6
31
53
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.3
16.5
33
60
S22.3
ICD-10 Finland
Fracture of rib
1.8
16.5
280
1585
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
5.8
16.5
30
50
F01.12
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly hallucinations
+∞
16.4
16
*
S00.0
ICD-10 Finland
Superficial injury of scalp
2.4
16.4
115
474
N05AA02
ATC
levomepromazine; systemic
2.2
16.3
146
666
WYA30, ,
SPAT
5.0
16.3
35
68
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.4
16.3
57
161
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
16.3
1299
10107
F01.13
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly depression
164.5
16.3
17
*
SPAT1304
SPAT
Counselling and guidance related to ageing
1.6
16.2
442
2824
K08.3
ICD-10 Finland
Retained dental root
1.8
16.2
256
1421
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
16.0
162
2961
I63.8
ICD-10 Finland
Other cerebral infarction
2.9
16.0
73
242
A10BB12
ATC
glimepiride; oral
1.5
16.0
485
3174
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.6
15.9
354
2154
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
5.0
15.9
34
66
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
15.8
423
5990
S01.8
ICD-10 Finland
Open wound of other parts of head
3.0
15.8
68
218
W10
ICD-10 Finland
Fall on and from stairs and steps
1.9
15.8
193
987
I63
ICD-10 Finland
Cerebral infarction
3.3
15.8
58
169
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
2.3
15.7
114
477
N43
ICPC
Neurological, Other diagnostic procedure
4.6
15.7
37
78
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.1
15.5
139
635
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
2.4
15.5
107
438
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
15.4
848
6215
ICB01, ,
SPAT
6.5
15.4
25
37
N17
ICPC
Vertigo/dizziness
1.5
15.4
493
3265
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
2.3
15.3
116
495
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
2.8
15.2
78
276
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
15.2
593
4084
T90.5
ICD-10 Finland
Sequelae of intracranial injury
4.2
15.0
40
93
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.7
14.9
28
48
F07.9
ICD-10 Finland
Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
27.7
14.9
20
7
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
14.8
1071
8192
SPAT1263
SPAT
Sampling
1.3
14.7
1384
10986
SPAT1125
SPAT
Stoma care and guidance
2.3
14.7
108
455
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
13.5
14.7
25
18
A10BH01
ATC
sitagliptin; oral
1.6
14.6
393
2502
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
2.7
14.6
80
293
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
14.6
1014
7706
R47.0
ICD-10 Finland
Dysphasia and aphasia
2.8
14.5
73
256
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
14.4
1090
8387
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
14.3
746
5409
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
14.3
841
6222
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.7
14.3
250
1429
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
145.1
14.3
15
*
G04BD08
ATC
solifenacin; oral
1.6
14.2
307
1854
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
14.2
873
6503
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
2.8
14.1
70
244
Z73.6
ICD-10 Finland
Limitation of activities due to disability
3.5
14.1
47
129
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
2.1
14.0
130
602
A46
ICD-10 Finland
Erysipelas
1.4
14.0
652
4636
N03AX09
ATC
lamotrigine; oral
2.8
14.0
70
245
Z43.5
ICD-10 Finland
Attention to cystostomy
3.4
13.9
49
139
R4130
NOMESCO Finland
Speech therapy
2.3
13.9
100
417
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
3.7
13.9
43
112
ZXA00
NOMESCO Finland
Right side
1.3
13.7
1127
8767
H53.4
ICD-10 Finland
Visual field defects
2.3
13.6
102
433
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
13.6
394
2549
N05CF01
ATC
zopiclone; oral
1.3
13.6
1478
11935
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
13.6
257
1500
N03AX18
ATC
lacosamide; systemic
6.0
13.5
24
39
SPAT1127
SPAT
Enema
2.9
13.4
63
213
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
+∞
13.4
13
*
F00, F03,
ICD-10 Finland
+∞
13.4
13
*
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.6
13.4
357
2270
G72.8
ICD-10 Finland
Other specified myopathies
2.3
13.0
93
387
G31.0
ICD-10 Finland
Circumscribed brain atrophy
5.1
13.0
27
51
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
13.0
17
838
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
2.4
13.0
92
382
N03AF01
ATC
carbamazepine; oral, rectal
1.7
12.9
233
1342
AXX01, ,
SPAT
2.2
12.9
113
513
NF1AA
NOMESCO Finland
Hip X-ray examination
1.5
12.6
400
2641
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
5.1
12.6
26
49
G04CB01
ATC
finasteride; oral
1.4
12.5
732
5400
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
2.1
12.5
116
538
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
1.7
12.5
227
1311
S42.2
ICD-10 Finland
Fracture of upper end of humerus
1.7
12.5
213
1209
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
12.4
281
1717
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.6
12.4
332
2111
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
3.0
12.4
54
175
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.2
12.4
9
522
A10AC01
ATC
insulin (human); parenteral
1.5
12.4
415
2770
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.4
12.4
44
126
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.7
12.4
39
103
SPAT1336
SPAT
Request for examination
1.9
12.3
158
822
F01.83
ICD-10 Finland
Other specified vascular dementia other additional symptoms, mainly depression
+∞
12.3
12
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
12.2
180
978
S20.2
ICD-10 Finland
Contusion of thorax
1.8
12.2
178
965
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
12.2
313
1973
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
12.2
1296
10405
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.0
12.1
129
630
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.0
12.1
135
670
T90
ICPC
Diabetes non-insulin dependent
1.3
12.1
862
6552
G04BD04
ATC
oxybutynin; oral, transdermal
1.6
12.1
316
2000
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.0
12.0
131
645
A02BC02
ATC
pantoprazole; systemic
1.3
12.0
2405
20794
205
Kela drug reimbursment
Chronic hypertension
1.3
12.0
1702
14141
P15
ICPC
Chronic alcohol abuse
3.2
12.0
47
143
K28
ICPC
Limited function/disability (K)
2.0
12.0
126
613
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
5.0
11.8
25
48
WX002
NOMESCO Finland
Sedation and analgesia
1.4
11.8
697
5147
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
11.8
777
5836
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.8
11.7
163
871
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
4.7
11.7
27
56
SPAT1111
SPAT
Planning of analgesia
2.8
11.7
57
197
L76
ICPC
Fracture: other
2.0
11.7
129
639
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
11.6
621
4510
Y94.8
ICD-10 Finland
Other leisure activity accident
2.4
11.6
81
334
B03BA03
ATC
hydroxocobalamin; parenteral
1.5
11.6
320
2048
G20
ICD-10 Finland
Parkinson disease
1.9
11.6
150
784
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
3.0
11.5
50
162
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
14.1
11.5
19
13
U13
ICPC
Bladder symptom/complaint other
2.0
11.5
117
563
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.3
11.5
916
7070
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
3.9
11.4
33
82
315
Kela drug reimbursment
Clopidogrel
2.3
11.4
86
368
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
2.7
11.3
59
212
N06AB03
ATC
fluoxetine; oral
1.5
11.2
307
1963
G21.8
ICD-10 Finland
Other secondary parkinsonism
8.9
11.2
23
25
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
11.1
1811
15245
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.9
11.1
137
704
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.6
11.1
36
97
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
3.8
11.0
33
84
P28
ICPC
Limited function/disability (P)
4.2
11.0
29
67
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
2.7
11.0
58
209
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.2
11.0
20
798
C04AE01
ATC
ergoloid mesylates; systemic
2.6
11.0
63
237
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.7
10.9
34
89
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
10.9
281
1772
Z60.8
ICD-10 Finland
Other problems related to social environment
4.8
10.9
24
48
R1260
NOMESCO Finland
Evaluation of communicative skills
2.2
10.8
88
388
A04AA02
ATC
granisetron; systemic, transdermal
0.3
10.8
34
996
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
2.6
10.8
60
223
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
3.1
10.7
44
138
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.0
10.7
108
518
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.1
10.7
104
492
ZY000
NOMESCO Finland
Hospital inpatient
4.6
10.6
25
53
XCK10
NOMESCO Finland
Photography of fundus of eye
1.4
10.6
428
2961
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.7
10.6
325
4499
N05BE01
ATC
buspirone; oral
2.4
10.6
68
271
SPAT1251
SPAT
Organisation of medication
1.7
10.5
186
1067
H02AA02
ATC
fludrocortisone; oral
2.9
10.5
47
155
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
17.2
10.5
16
9
N30
ICD-10 Finland
Cystitis
1.6
10.5
232
1412
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
58.0
10.4
12
*
F01.82
ICD-10 Finland
Other specified vascular dementia other additional symptoms, mainly hallucinations
58.0
10.4
12
*
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.4
10.4
415
2862
SPAT1050
SPAT
Extensive neurological examination
2.2
10.4
81
351
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
10.4
17
723
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
2.1
10.4
101
478
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
4.1
10.4
28
66
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
10.3
1594
13309
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
10.3
10
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
1.8
10.3
152
829
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.3
10.2
655
4889
P03
ICPC
Feeling depressed
1.9
10.2
123
628
R51.80
ICD-10 Finland
Headache
1.5
10.2
339
2258
Z72.1
ICD-10 Finland
Alcohol use
3.8
10.2
31
80
G41.9
ICD-10 Finland
Status epilepticus, unspecified
3.6
10.2
33
89
S97
ICPC
Chronic ulcer skin
1.5
10.2
280
1792
I95.2
ICD-10 Finland
Hypotension due to drugs
2.8
10.2
50
174
N88
ICPC
Epilepsy
4.4
10.1
25
55
D07AA02
ATC
hydrocortisone; topical
1.4
10.1
417
2894
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.3
10.1
22
785
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
1.9
10.0
124
640
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.0
10.0
42
134
D10
ICPC
Vomiting
2.2
10.0
86
389
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
3.8
10.0
30
77
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
9.9
929
7305
F32
ICD-10 Finland
Depressive episode
2.1
9.9
88
403
H25.1
ICD-10 Finland
Senile nuclear cataract
1.2
9.8
1764
14947
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
0.0
9.8
*
269
N06AX12
ATC
bupropion; oral
2.5
9.8
60
234
S09.9
ICD-10 Finland
Unspecified injury of head
2.5
9.8
61
240
U28
ICPC
Limited function/disability (U)
2.5
9.8
61
240
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
9.8
240
1498
XQ855, ,
SPAT
3.3
9.8
36
106
Z29
ICPC
Social problem NOS
2.2
9.7
75
325
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
9.6
1192
9690
G40
ICD-10 Finland
Epilepsy
3.9
9.6
28
70
N06AA12
ATC
doxepin; systemic
1.6
9.6
212
1289
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
9.6
1347
11107
WX320
NOMESCO Finland
Spinalanesthesy
1.3
9.6
824
6408
Z2446
NOMESCO Finland
Social worker
1.6
9.5
226
1399
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
8.4
9.5
20
23
J01CA04
ATC
amoxicillin; systemic
1.2
9.5
2549
22474
G81.9
ICD-10 Finland
Hemiplegia, unspecified
2.6
9.5
52
192
N05BA01
ATC
diazepam; systemic, rectal
1.4
9.5
488
3520
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.6
9.5
196
1174
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.6
9.4
53
198
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
3.6
9.4
30
80
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
2.9
9.4
42
139
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.0
9.4
41
134
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.0
9.4
40
129
Z02.8
ICD-10 Finland
Other examinations for administrative purposes
4.1
9.3
25
59
F001, G301,
ICD-10 Finland
96.7
9.3
10
*
XF606
NOMESCO Finland
Ortostatic test
3.0
9.2
40
130
R31
ICD-10 Finland
Unspecified haematuria
1.4
9.2
509
3711
SPAT1107
SPAT
Extensive external surface anaesthesia of skin with cream or gel
3.8
9.2
27
68
SPAT1062
SPAT
Lung clearance therapy
3.8
9.2
27
68
A10BH05
ATC
linagliptin; oral
1.5
9.2
252
1612
H3600, E113,
ICD-10 Finland
2.2
9.2
73
320
S00.8
ICD-10 Finland
Superficial injury of other parts of head
2.3
9.1
66
278
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
3.3
9.1
34
101
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.3
9.1
561
4162
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
9.1
176
1037
L81
ICPC
Injury musculoskeletal NOS
2.3
9.0
66
280
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
1.8
8.9
139
772
J01CF05
ATC
flucloxacillin; systemic
1.7
8.9
166
969
K59.09
ICD-10 Finland
Constipation, unspecified
1.5
8.9
278
1831
TKC20
NOMESCO Finland
Catheterisation of bladder
1.4
8.8
365
2534
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
1.8
8.8
125
674
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.2
8.8
1574
13285
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
1.9
8.8
111
577
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
2.0
8.8
92
449
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
2.9
8.8
40
134
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
3.2
8.7
34
104
S01.9
ICD-10 Finland
Open wound of head, part unspecified
2.2
8.7
69
303
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
4.0
8.7
24
58
UKC02
NOMESCO Finland
Cystoscopy
1.3
8.6
794
6223
R44.0
ICD-10 Finland
Auditory hallucinations
4.4
8.6
21
46
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.6
8.5
175
1046
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
0.5
8.5
71
1379
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
0.2
8.5
14
588
N19
ICPC
Speech disorder
2.4
8.5
55
221
I95.9
ICD-10 Finland
Hypotension, unspecified
2.1
8.4
79
370
N06AG02
ATC
moclobemide; oral
1.8
8.4
115
613
U05
ICPC
Urination problems other
1.6
8.4
206
1286
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
1.8
8.4
133
742
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
3.3
8.4
30
87
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
4.5
8.4
20
43
R45.5
ICD-10 Finland
Hostility
19.3
8.3
12
6
A08.1
ICD-10 Finland
Acute gastroenteropathy due to Norovirus
3.9
8.3
24
60
Z51.5
ICD-10 Finland
Palliative care
1.4
8.3
398
2838
ZXE00
NOMESCO Finland
One hour or less
1.2
8.3
1318
10980
QAB00
NOMESCO Finland
Suture of skin of head or neck
2.4
8.2
53
212
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
+∞
8.2
8
*
F0011, G301,
ICD-10 Finland
+∞
8.2
8
*
N03AX16
ATC
[U] pregabalin
1.3
8.2
736
5745
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
0.2
8.2
12
543
D21
ICPC
Swallowing problem
2.2
8.2
63
273
R50.9
ICD-10 Finland
Fever, unspecified
1.3
8.2
503
3729
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
4.2
8.1
21
48
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.3
8.1
17
618
A23
ICPC
Risk factor NOS
1.7
8.1
158
933
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
8.1
993
8040
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
8.1
1565
13284
E87.6
ICD-10 Finland
Hypokalaemia
1.7
8.1
133
750
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.3
8.1
22
692
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.5
8.1
219
1399
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.2
8.1
65
287
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
0.2
8.1
6
339
Z03
ICPC
Housing/neighbourhood problem
3.2
8.1
31
94
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
2.2
8.1
63
275
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.2
8.0
1661
14186
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
1.6
8.0
183
1124
WZC30
NOMESCO Finland
Teaching
0.7
8.0
214
3050
G46.8
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
14.0
8.0
13
9
I68.0
ICD-10 Finland
Cerebral amyloid angiopathy
14.0
8.0
13
9
SPAT1014
SPAT
Treatment of eyes
2.0
8.0
83
404
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
2.4
8.0
54
221
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
1.9
8.0
103
540
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
2.2
8.0
62
270
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
1.6
8.0
180
1103
WX704
NOMESCO Finland
Intubation
1.6
8.0
198
1241
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
2.3
8.0
60
258
Z28
ICPC
Limited function/disability (Z)
3.2
7.9
30
90
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
3.2
7.9
30
90
F31.8
ICD-10 Finland
Other bipolar affective disorders
4.7
7.9
18
37
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
7.3
7.9
18
24
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
3.0
7.8
33
106
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.0
7.8
86
428
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.6
7.8
161
966
N03AE01
ATC
clonazepam; systemic
1.6
7.8
164
989
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
2.0
7.8
80
389
S72.8
ICD-10 Finland
Fractures of other parts of femur
3.4
7.7
27
77
IAB14
NOMESCO Finland
Geriatric psychiatry consultation
7.0
7.7
18
25
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.4
7.7
330
2308
X58
ICD-10 Finland
Exposure to other specified factors
1.4
7.7
304
2096
Z01.9
ICD-10 Finland
Special examination, unspecified
1.6
7.7
162
977
E000003, ,
ATC
1.7
7.6
123
690
S20
ICPC
Corn/callosity
2.0
7.6
80
392
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.1
7.6
73
346
P76
ICPC
Depressive disorder
2.1
7.6
73
346
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
7.6
1389
11710
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
2.5
7.6
44
168
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
9.1
7.6
15
16
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.6
7.5
170
1042
Z60.9
ICD-10 Finland
Problem related to social environment, unspecified
4.1
7.5
20
47
P05
ICPC
Senility, feeling/behaving old
2.8
7.5
37
130
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
7.5
898
7247
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.6
7.5
173
1067
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.4
7.5
34
833
A04AA01
ATC
ondansetron; systemic, rectal
0.5
7.4
86
1505
R40.2
ICD-10 Finland
Coma, unspecified
2.4
7.4
49
199
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.5
7.4
236
1562
L01BC06
ATC
capecitabine; oral
0.3
7.4
24
686
SPAT1240
SPAT
Therapeutic discussion
1.7
7.3
140
823
SPAT1284
SPAT
Extensive health certificate
2.1
7.3
70
331
A78
ICPC
Infectious disease other/NOS
2.6
7.3
40
148
S80.0
ICD-10 Finland
Contusion of knee
1.6
7.3
162
988
N05AF05
ATC
zuclopenthixol; systemic
4.0
7.3
20
48
B99
ICD-10 Finland
Other and unspecified infectious diseases
1.9
7.3
88
452
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
77.4
7.3
8
*
F06.0
ICD-10 Finland
Organic hallucinosis
5.9
7.3
19
31
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
0.4
7.3
45
973
G40.89
ICD-10 Finland
Other epilepsy
4.2
7.3
19
44
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
1.7
7.2
114
636
F009, F03,
ICD-10 Finland
+∞
7.2
7
*
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.8
7.2
21
53
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.5
7.2
187
1186
G40.10
ICD-10 Finland
Simple partial seizures
3.2
7.2
28
86
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.4
7.1
342
2437
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.7
7.1
121
690
S42.4
ICD-10 Finland
Fracture of lower end of humerus
2.4
7.1
47
191
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
3.9
7.1
20
49
SPAT1313
SPAT
Guidance and counselling related to accident prevention
2.9
7.1
32
107
B01AB05
ATC
enoxaparin; parenteral
1.2
7.1
1073
8870
A05
ICPC
Feeling ill
1.7
7.1
126
728
R1250, ,
SPAT
2.3
7.1
53
228
WX720
NOMESCO Finland
Own respiration
1.7
7.1
118
670
SPAT1153
SPAT
Removal of sutures
0.8
7.0
715
8313
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
0.5
7.0
58
1128
J01XE01
ATC
nitrofurantoin; oral
1.8
7.0
91
479
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
3.5
7.0
23
63
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
7.0
310
2180
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
6.0
7.0
18
29
N27
ICPC
Fear of neurological disease other
2.1
7.0
59
267
TNG34
NOMESCO Finland
Major custom moulded orthopaedic cast, knee or lower leg
2.6
7.0
38
141
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
2.2
6.9
55
242
S22.4
ICD-10 Finland
Multiple fractures of ribs
1.9
6.9
83
426
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.5
6.9
188
1204
N39
ICD-10 Finland
Other disorders of urinary system
2.6
6.9
37
136
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.6
6.9
153
936
Z93.5
ICD-10 Finland
Cystostomy status
4.0
6.9
19
46
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
4.0
6.9
19
46
B01AF02
ATC
apixaban; oral
1.3
6.9
597
4636
IGP01
NOMESCO Finland
Psychiatric family contact
9.7
6.9
13
13
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
6.9
738
5879
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
4.1
6.8
18
42
A10BD07
ATC
metformin and sitagliptin; systemic
1.7
6.8
131
773
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
1.6
6.8
143
863
I69
ICD-10 Finland
Sequelae of cerebrovascular disease
3.0
6.8
28
89
P04
ICPC
Feeling/behaving irritable/angry
6.7
6.8
16
23
KMAK, ,
NOMESCO Finland
1.2
6.8
1060
8783
A10AD05
ATC
insulin aspart; parenteral
1.7
6.8
126
737
K43
ICPC
Cardiovascular, Other diagnostic procedure
2.1
6.7
58
264
R06AE07
ATC
cetirizine; oral
1.2
6.7
1081
8979
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
1.7
6.7
123
717
Z75.0
ICD-10 Finland
Medical services not available in home
3.6
6.7
21
56
NFJ50
NOMESCO Finland
Internal fixation of fracture of neck of femur with nail or screw
2.6
6.7
36
133
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
1.6
6.7
132
785
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
1.8
6.6
93
502
L57.0
ICD-10 Finland
Actinic keratosis
0.7
6.6
330
4215
H3601, E113,
ICD-10 Finland
1.9
6.6
75
379
A99
ICPC
Disease/condition unspecnature/site
1.4
6.6
296
2089
U07
ICPC
Urine symptom/complaint other
1.4
6.6
250
1713
N87
ICPC
Parkinsonism
2.2
6.6
51
223
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.9
6.6
84
441
G04BD09
ATC
trospium; oral
1.7
6.6
110
626
PA7BD
NOMESCO Finland
CT angiography of neck and brain
2.1
6.5
57
261
P72
ICPC
Schizophrenia
3.3
6.5
24
71
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
3.3
6.5
24
71
R60.0
ICD-10 Finland
Localized oedema
1.3
6.5
495
3776
ZXD20
NOMESCO Finland
Day surgery
1.3
6.5
381
2802
NFB10
NOMESCO Finland
Primary partial prosthetic replacement of hip joint not using cement, other or unspecified
2.8
6.5
31
107
N04AA02
ATC
biperiden; systemic
2.3
6.5
45
187
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
6.5
989
8174
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
0.5
6.4
49
979
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
2.4
6.4
42
170
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.0
6.4
62
295
SPAT1285
SPAT
Provision of consultation response
1.5
6.4
163
1028
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.4
1045
8685
Z50.1
ICD-10 Finland
Other physical therapy
1.5
6.4
182
1176
N05AC02
ATC
thioridazine; oral
2.2
6.4
50
219
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
3.1
6.4
25
77
G91.0
ICD-10 Finland
Communicating hydrocephalus
3.1
6.4
25
77
SPAT1265
SPAT
Breathalyser
4.1
6.4
17
40
NFQ20
NOMESCO Finland
Amputation of femur
2.0
6.4
68
336
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.4
6.4
43
177
R35
ICD-10 Finland
Polyuria
1.4
6.3
251
1732
F002, G308,
ICD-10 Finland
67.4
6.3
7
*
A60
ICPC
General and Unspecified, Result test/procedure
1.6
6.3
146
902
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
2.8
6.3
31
109
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
3.0
6.3
27
88
C09BA02
ATC
enalapril and diuretics; systemic
1.3
6.3
386
2860
L17
ICPC
Foot/toe symptom/complaint
1.2
6.3
821
6675
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
1.8
6.3
86
462
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
6.0
6.3
16
26
C10AA03
ATC
pravastatin; oral
1.4
6.3
319
2298
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
0.7
6.3
284
3679
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.9
6.2
18
45
EB4VA, ,
NOMESCO Finland
0.3
6.2
22
603
A96
ICPC
Death
2.6
6.2
35
132
A27
ICPC
Fear of other disease NOS
1.6
6.2
146
906
K92.0
ICD-10 Finland
Haematemesis
1.7
6.2
118
695
G04BD11
ATC
fesoterodine; oral
1.7
6.2
117
688
D64.9
ICD-10 Finland
Anaemia, unspecified
1.3
6.2
580
4544
KCV04
NOMESCO Finland
Distension of bladder with fluid
2.6
6.2
34
127
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
1.8
6.2
84
450
D09
ICPC
Nausea
1.8
6.2
94
521
F00.2
ICD-10 Finland
Dementia in Alzheimer disease, atypical or mixed type
+∞
6.2
6
*
F0013, G301,
ICD-10 Finland
+∞
6.2
6
*
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.5
6.2
210
1410
IHZ08, ,
SPAT
7.9
6.2
13
16
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.2
6.2
2006
17696
D12
ICPC
Constipation
1.6
6.1
139
855
S32.5
ICD-10 Finland
Fracture of pubis
2.0
6.1
59
281
S50.0
ICD-10 Finland
Contusion of elbow
2.0
6.1
62
301
ZX120, ,
SPAT
2.5
6.1
37
145
S72.2
ICD-10 Finland
Subtrochanteric fracture
2.1
6.1
53
243
N99
ICPC
Neurological disease other
2.4
6.1
38
151
-2, ,
ICPC
2.6
6.1
34
128
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
5.3
6.1
17
31
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
0.2
6.1
6
285
J96.1
ICD-10 Finland
Chronic respiratory failure
0.5
6.1
46
919
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.6
6.1
124
744
S89.8
ICD-10 Finland
Other specified injuries of lower leg
3.8
6.1
18
46
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
0.2
6.1
8
320
S06.2
ICD-10 Finland
Diffuse brain injury
2.5
6.1
35
134
WX892
NOMESCO Finland
Monitored bed care
1.4
6.1
281
1994
L75
ICPC
Fracture: femur
1.9
6.0
71
363
F32.8
ICD-10 Finland
Other depressive episodes
3.0
6.0
26
85
XX1XW
NOMESCO Finland
Extensive written report from radiologist
1.9
6.0
68
343
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.1
6.0
55
257
SPAT1260
SPAT
Consultation of another employee
1.3
6.0
535
4164

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1534
7458
2.52
168.32
2.0
1.8
1036.77
1160.08
nmol/l
6.36
1164
5436
1903
11060
2.17
129.36
4.6
3.8
—
—
—
0
0
2105
13102
2.06
115.30
2.6
2.2
89.53
91.68
pmol/l
1.32
1221
6711
159
196
8.08
114.83
3.5
3.3
327.91
327.80
umol/l
0.00
127
158
1711
10174
2.02
103.11
4.6
4.3
—
—
—
0
0
1569
9112
2.03
100.38
2.5
2.1
280.93
226.80
u/l
1.31
1475
8424
97
74
12.90
98.27
1.0
1.0
677.69
760.37
ng/l
0.63
68
38
95
74
12.63
95.04
1.0
1.0
340.39
250.17
ng/l
1.84
72
41
1386
7859
2.03
93.41
1.8
1.6
17.89
19.69
nmol/l
4.00
1248
6625
1664
10368
1.89
82.64
2.3
2.2
75.99
81.08
nmol/l
10.18
1423
8770
2241
15402
1.83
80.55
6.5
6.5
1.22
1.21
mmol/l
7.57
1897
12836
2607
18963
1.81
75.59
7.4
5.7
3814.57
2018.14
e6/l
0.40
51
338
1969
13369
1.77
70.39
4.3
4.4
33.41
33.57
g/l
0.56
1747
12161
1555
9900
1.80
68.91
2.5
3.2
2.35
2.35
mmol/l
0.09
1299
8283
1125
6619
1.86
63.57
5.1
4.6
146.67
558.56
ng/l
2.50
1036
6011
1046
6109
1.86
59.99
3.0
3.1
2.48
2.47
mmol/l
0.05
865
5125
1974
13908
1.67
57.81
5.6
5.8
1.21
1.21
mmol/l
3.27
1784
12442
2492
18717
1.66
56.34
6.6
5.1
—
—
—
0
0
2299
17053
1.63
53.38
5.5
4.7
7.25
6.99
mmol/l
4.52
2165
16021
2199
16235
1.62
51.18
23.8
23.6
1.52
1.50
inr
0.24
543
4493
1383
9187
1.66
48.61
3.5
3.9
7.40
7.40
ph
1.08
209
1745
1440
9788
1.62
45.53
4.4
3.6
84.68
139.64
e6/l
1.58
1125
7711
2391
18361
1.57
44.38
34.3
27.4
328.99
329.73
g/l
3.13
2310
18016
1366
9216
1.62
44.25
2.4
2.4
3.09
3.30
mg/l
1.59
1135
7747
1547
10852
1.58
42.06
5.1
4.1
289.25
145.75
e6/l
1.73
1144
8149
2985
24304
1.58
41.30
27.4
20.4
29.81
29.87
mg/l
0.03
2728
20695
1057
6815
1.65
40.38
1.8
1.8
432.46
9305809.32
pmol/l
1.96
861
5341
2705
21591
1.55
40.36
5.0
4.8
2.01
2.14
mu/l
4.28
2430
18859
1795
13177
1.53
39.00
3.4
3.1
57.39
59.05
u/l
0.26
1598
11685
1067
6964
1.63
38.56
4.1
3.2
560.33
532.10
mosm/kgh2o
4.79
903
5945
134
374
3.53
38.55
1.4
1.3
757.66
588.79
mg/l
0.39
125
356
839
5158
1.70
38.14
3.7
3.3
3.02
2.28
e6/l
0.86
455
2972
122
322
3.73
38.13
1.3
1.2
4.29
3.97
mmol/l
1.62
113
290
117
316
3.64
35.37
1.5
1.4
979.89
930.99
e6/l
0.03
94
263
315
1438
2.20
35.11
4.3
4.4
0.92
0.86
%
2.14
299
1352
116
315
3.62
34.79
1.4
1.3
6.83
37.86
e6/l
0.97
90
253
314
1455
2.16
33.69
4.3
4.4
1.59
1.53
%
0.75
298
1370
1273
8922
1.53
32.89
4.3
3.5
0.61
0.59
e6/l
0.15
1003
7025
611
3572
1.76
32.86
3.5
3.5
1.81
1.99
mmol/l
0.55
514
2909
800
5039
1.65
32.61
1.7
1.9
29.89
30.62
s
2.40
774
4854
2548
20575
1.47
32.04
6.5
7.3
83.01
85.22
u/l
0.94
2355
19049
2209
17368
1.46
31.84
3.6
3.8
15.26
15.30
pmol/l
0.26
1951
15078
522
2941
1.81
31.77
3.3
3.0
4.21
4.32
kpa
0.60
495
2805
183
685
2.64
31.68
4.6
5.8
11.34
11.27
mmol/l
0.08
167
610
183
685
2.64
31.68
4.6
5.9
104.75
104.44
mmol/l
0.36
167
610
607
3578
1.74
31.63
3.6
3.5
5.76
5.82
kpa
0.83
580
3432
1935
14932
1.45
30.18
4.3
5.6
12.46
13.05
umol/l
1.07
1805
14067
106
300
3.47
29.91
1.3
1.3
—
—
—
0
0
234
1014
2.29
29.53
4.7
5.2
1.35
1.41
mmol/l
0.36
210
898
839
5466
1.59
29.49
3.6
3.1
1.25
1.40
e6/l
0.62
453
3257
1202
8485
1.51
29.38
4.3
3.5
—
—
—
0
0
1420
10395
1.47
28.85
5.1
4.1
5.92
5.91
ph
0.02
19
247
3009
25474
1.45
26.69
32.7
24.9
139.33
139.25
mmol/l
0.71
2898
24619
3010
25496
1.45
26.52
32.9
25.1
4.00
4.03
mmol/l
6.72
2888
24593
1677
12843
1.42
26.02
5.8
4.5
0.00
0.00
estimate
1.15
286
2675
1660
12701
1.42
25.84
5.4
4.8
147.79
69.32
ng/l
0.35
1319
10339
1688
12957
1.42
25.79
5.8
4.5
0.00
0.00
estimate
-0.00
234
2391
3016
25648
1.43
25.25
36.9
29.7
7.57
7.22
e9/l
6.47
2862
24497
3016
25650
1.43
25.23
37.2
30.0
125.40
128.64
g/l
25.50
2912
24952
3015
25640
1.43
25.23
37.2
29.8
36.79
38.08
%
13.57
2548
23247
606
3777
1.64
25.21
4.0
3.4
344.79
336.38
ng/l
0.14
561
3445
3015
25641
1.43
25.21
36.9
29.7
234.64
233.05
e9/l
0.60
2877
24615
3015
25643
1.43
25.18
36.8
29.6
30.33
30.41
pg
1.31
2907
24921
3015
25645
1.43
25.16
36.8
29.7
92.02
92.10
fl
0.34
2906
24925
3015
25645
1.43
25.16
36.9
29.7
4.18
4.26
e12/l
16.71
2853
24490
393
2200
1.79
24.19
3.6
3.2
126.05
123.98
g/l
1.13
384
2145
143
546
2.58
23.83
1.5
1.9
25.69
32.69
umol/l
3.09
114
468
1655
12791
1.40
23.72
8.4
6.0
0.00
0.00
estimate
-0.00
234
2403
153
608
2.48
23.46
3.1
2.6
—
—
—
0
0
154
615
2.47
23.36
3.0
2.6
106.23
105.38
mmol/l
1.01
154
609
154
615
2.47
23.36
3.0
2.6
4.15
4.15
mmol/l
0.02
154
609
2269
18654
1.36
21.38
4.1
4.3
17.65
17.02
mm/h
0.84
2044
16766
1008
7257
1.44
21.09
2.8
2.9
36.86
37.26
u/l
0.06
924
6745
1183
8790
1.41
20.69
2.5
2.5
55.91
60.39
u/l
1.81
1095
8022
2834
24201
1.37
20.49
25.6
19.9
—
—
—
0
0
972
7024
1.43
19.74
3.3
2.8
5.29
4.91
e6/l
0.50
876
6271
306
1690
1.80
19.64
2.6
2.5
0.65
0.66
%
0.25
306
1681
311
1730
1.79
19.48
2.7
2.5
1.06
1.14
%
1.17
311
1722
1426
11022
1.37
19.38
3.0
3.0
135.80
157.20
ug/l
3.14
1260
9796
2350
19624
1.34
18.92
31.8
23.8
15.31
15.66
%
2.70
2273
19106
153
678
2.22
18.36
1.2
1.2
—
—
—
0
0
1583
12512
1.35
18.35
5.0
5.6
22.68
24.15
%
5.02
1438
11427
1548
12257
1.34
17.51
4.9
5.3
61.81
60.28
%
4.72
1407
11204
1512
11945
1.34
17.32
4.5
5.3
0.55
0.60
%
2.31
1374
10888
1550
12330
1.33
16.79
5.1
5.6
8.83
9.04
%
1.65
1406
11243
1543
12268
1.33
16.77
4.7
5.3
2.71
2.76
%
0.30
1397
11184
224
1182
1.87
16.65
2.1
2.2
912.57
625.44
ug/l
0.40
200
1123
295
1691
1.73
16.64
2.6
3.4
24.08
24.06
mmol/l
0.04
280
1621
221
1167
1.87
16.39
7.7
4.9
—
—
—
0
0
953
7070
1.38
16.18
3.7
4.0
76.38
78.69
%
1.93
924
6882
2867
24906
1.32
16.09
10.8
11.3
22.61
23.06
u/l
0.28
2709
23533
340
2055
1.65
15.72
1.8
2.0
401.64
389.11
nmol/l
0.51
304
1823
797
9985
0.72
15.35
2.1
2.4
—
—
—
0
0
326
1962
1.65
15.33
4.3
3.5
25.37
24.92
mmol/l
1.53
314
1902
1620
13148
1.30
14.61
4.6
5.1
1.81
1.83
e9/l
0.11
1318
11229
291
1725
1.67
14.51
7.1
7.7
—
—
—
0
0
1821
15017
1.29
14.49
5.8
7.7
4.96
4.59
e9/l
6.15
1472
12784
594
4149
1.44
14.08
5.0
5.5
1.60
1.13
mmol/l
1.85
448
3159
1630
13296
1.29
13.96
4.5
5.1
0.20
0.20
e9/l
0.18
1320
11228
1590
12933
1.29
13.90
4.4
5.0
0.04
0.04
e9/l
0.15
1287
10798
659
4712
1.41
13.69
2.1
2.2
1.78
1.77
%
0.12
531
4062
691
4987
1.40
13.59
2.1
2.6
0.81
0.82
mmol/l
1.51
596
4516
1579
12869
1.29
13.48
4.4
5.0
0.67
0.65
e9/l
1.60
1275
10725
76
284
2.61
13.38
3.4
3.3
—
—
—
0
0
589
4146
1.43
13.34
5.1
5.5
5.01
5.02
kpa
0.10
534
3861
589
4146
1.43
13.34
5.1
5.5
10.83
11.44
kpa
2.32
531
3855
868
6525
1.35
13.23
6.5
4.4
—
—
—
0
0
405
2659
1.52
13.09
3.0
3.5
100.28
103.22
ng/l
0.26
309
2211
54
171
3.07
12.90
1.4
1.3
—
—
—
0
0
768
5692
1.37
12.78
2.3
2.5
10.11
11.27
umol/l
5.38
684
5171
507
3500
1.45
12.74
1.8
1.8
—
—
—
0
0
355
2284
1.54
12.59
5.3
5.9
24.74
24.38
mmol/l
0.88
334
2173
44
129
3.31
11.94
1.4
1.3
—
—
—
0
0
715
5320
1.35
11.50
2.3
2.5
2.19
2.22
g/l
0.86
636
4822
289
1815
1.57
11.41
7.0
4.3
—
—
—
0
0
134
680
1.93
11.31
1.6
2.2
—
—
—
0
0
763
5755
1.34
11.19
6.0
5.0
1.01
1.02
kg/l
0.42
148
989
91
406
2.19
10.89
1.2
1.2
—
—
—
0
0
511
3637
1.40
10.77
5.5
5.8
94.44
95.07
%
0.83
475
3476
143
2401
0.56
10.62
1.2
1.3
—
—
—
0
0
32
83
3.74
10.45
2.3
2.1
57.54
50.58
umol/l
0.59
24
67
677
5067
1.34
10.40
2.3
2.6
18.80
20.44
%
2.52
496
4251
1148
9230
1.27
10.32
2.4
2.7
—
—
—
0
0
370
2506
1.46
10.23
3.8
3.9
—
—
—
0
0
456
3211
1.41
10.21
5.9
6.2
118.60
118.09
g/l
0.21
440
3123
29
73
3.85
9.88
1.4
1.4
—
—
—
0
0
2532
22268
1.23
9.84
7.1
7.0
43.48
41.91
mmol/mol
8.64
2267
19769
436
3073
1.41
9.71
2.1
2.5
10.03
10.52
umol/l
0.14
347
2655
810
6314
1.29
9.19
4.7
4.3
—
—
—
0
0
281
1848
1.50
9.02
3.5
3.0
0.24
0.37
e6/l
2.06
275
1819
418
2962
1.40
9.01
5.4
6.2
—
—
—
0
0
602
4538
1.32
8.72
4.1
4.8
1.03
1.05
mmol/l
1.28
514
4089
479
3506
1.36
8.46
2.5
2.6
4.51
5.94
ug/l
2.53
341
2906
387
2737
1.40
8.44
1.6
1.9
0.20
0.19
g/l
2.00
334
2480
361
2535
1.41
8.21
2.4
2.4
29.77
35.55
u/l
2.63
298
2110
43
156
2.67
8.16
1.4
1.2
—
—
—
0
0
175
1063
1.61
8.03
4.7
3.7
—
—
—
0
0
1443
12208
1.21
7.61
3.2
3.5
2475.60
2524.38
ng/l
0.13
1227
10666
1469
12451
1.21
7.59
2.6
2.8
—
—
—
0
0
423
3088
1.36
7.59
4.7
5.2
1.54
1.45
mmol/l
0.77
403
2941
1417
11978
1.21
7.52
4.7
5.7
—
—
—
0
0
26
74
3.40
7.48
3.0
2.6
31.25
30.06
umol/l
0.17
15
54
30
96
3.03
7.17
1.0
1.0
126.25
139.49
nmol/l
0.89
30
96
32
108
2.87
6.99
1.2
1.2
0.64
1.11
promille
1.07
25
81
264
3519
0.71
6.91
1.3
1.4
—
—
—
0
0
2568
23000
1.19
6.87
4.8
5.3
6.31
6.19
mmol/l
3.32
2243
19899
73
371
1.91
6.31
2.6
2.2
4.27
2.17
u/field
0.86
22
112
10
7
13.80
6.26
1.5
1.0
—
—
—
0
0
19
50
3.68
6.15
1.3
1.3
—
—
—
0
0
198
1323
1.46
5.97
1.2
1.2
—
—
—
0
0
26
86
2.93
5.92
1.2
1.4
81.46
79.49
umol/l
0.03
13
51
45
196
2.23
5.88
1.6
1.4
9.44
10.06
%
0.41
45
196
62
307
1.96
5.81
1.4
1.3
278.20
274.77
mosm/kgh2o
0.34
35
209
53
251
2.05
5.63
1.1
1.1
34.36
35.77
mmol/l
0.19
42
200
118
720
1.60
5.44
1.3
1.3
57.93
59.02
mmol/l
0.12
99
572
226
2964
0.72
5.39
1.2
1.2
11.97
17.88
u/ml
0.40
50
938
450
5358
0.79
5.34
4.0
3.6
—
—
—
0
0
1298
11153
1.17
5.33
4.7
5.8
5.34
6.35
ug/l
0.21
1094
9718
75
410
1.78
5.22
5.0
5.5
13.25
12.73
mg/l
0.44
64
364
188
1281
1.43
5.16
3.7
3.1
0.80
0.83
nmol/l
0.42
145
979
41
185
2.15
4.97
3.1
1.8
1.82
3.56
u/field
0.84
22
119
451
3520
1.26
4.96
2.4
2.3
66.00
66.41
e9/l
0.09
336
2685
1994
17775
1.15
4.90
4.7
4.8
—
—
—
0
0
545
4363
1.23
4.78
2.1
1.9
—
—
—
0
0
6
247
0.23
4.74
1.5
1.5
—
—
—
0
0
245
1774
1.35
4.71
1.4
1.4
—
—
—
0
0
229
1643
1.36
4.67
1.9
1.8
2.76
2.45
ug/l
0.14
171
1386
266
1954
1.33
4.65
5.5
3.6
—
—
—
0
0
18
57
3.05
4.46
1.3
1.5
—
—
—
0
0
124
1744
0.68
4.44
1.4
1.4
—
—
—
0
0
132
869
1.48
4.38
1.2
1.4
—
—
—
0
0
15
43
3.37
4.34
6.4
2.7
0.33
0.40
u/field
0.15
15
43
36
165
2.11
4.24
2.7
1.9
122.03
106.12
umol/l
0.48
36
165
63
350
1.75
4.22
2.0
2.0
—
—
—
0
0
67
381
1.71
4.14
3.9
3.2
—
—
—
0
0
57
312
1.77
4.03
1.4
1.3
273.17
311.56
nmol/l
0.65
40
226
21
78
2.60
3.95
1.3
1.4
—
—
—
0
0
209
1522
1.34
3.92
2.3
2.2
7.72
7.55
g/l
0.61
170
1334
154
1071
1.40
3.86
2.6
2.7
4.16
4.22
pmol/l
0.33
116
902
817
6934
1.17
3.77
2.2
2.6
—
—
—
0
0
207
1517
1.33
3.74
2.3
2.2
3.71
3.63
g/l
0.25
169
1329
1032
8935
1.15
3.62
4.4
5.0
22.72
22.62
%
0.07
505
4942
7
225
0.30
3.59
1.1
1.7
—
—
—
0
0
2501
22896
1.12
3.57
4.8
5.4
2.22
2.40
mmol/l
21.12
2250
20091
11
25
4.25
3.49
1.6
1.1
—
—
—
0
0
131
1739
0.72
3.46
1.5
1.6
—
—
—
0
0
43
723
0.57
3.42
1.2
1.1
—
—
—
0
0
494
5569
0.84
3.42
1.5
1.6
1.27
1.25
mmol/l
0.21
448
4528
264
3161
0.79
3.32
1.2
1.2
39.11
43.62
iu/ml
0.19
84
968
188
1385
1.32
3.31
2.4
2.2
2.99
3.09
g/l
0.60
149
1195
38
198
1.86
3.21
1.3
1.2
—
—
—
0
0
21
87
2.33
3.20
1.2
1.0
274.76
321.36
mg/l
0.67
21
75
38
201
1.83
3.08
3.8
3.4
—
—
—
0
0
337
2694
1.22
3.06
2.1
2.2
—
—
—
0
0
13
43
2.92
3.04
1.5
1.2
—
—
—
0
0
106
1419
0.71
2.99
1.1
1.2
—
—
—
0
0
400
3260
1.20
2.98
4.5
5.6
12.27
13.14
mmol/l
1.18
358
3006
19
78
2.35
2.97
1.6
1.7
54.29
48.14
ug/l
0.32
19
73
72
457
1.53
2.96
10.0
10.3
7.27
7.32
mmol/l
0.04
55
377
7
12
5.63
2.93
1.3
1.5
21.41
13.57
umol/l
—
7
12
9
234
0.37
2.91
3.7
3.2
16.89
48.25
u/ml
—
9
227
199
1508
1.29
2.89
1.4
1.5
—
—
—
0
0
25
465
0.52
2.86
1.3
1.6
16.75
22.23
ug/l
0.97
25
450
190
1436
1.29
2.82
2.4
2.2
10.02
10.46
g/l
0.64
151
1230
331
2667
1.21
2.80
3.8
3.8
1.23
1.22
mmol/l
1.46
288
2293
42
237
1.72
2.78
14.8
17.0
—
—
—
0
0
12
288
0.40
2.74
1.7
2.9
11.49
9.53
nmol/l
0.08
12
278
13
46
2.73
2.72
1.5
1.2
—
—
—
0
0
13
46
2.73
2.72
1.5
1.2
—
—
—
0
0
13
46
2.73
2.72
1.5
1.2
—
—
—
0
0
660
5651
1.15
2.69
1.6
1.6
1.45
1.67
mg/l
1.30
544
4431
16
338
0.45
2.66
1.6
1.5
129.81
291.28
pmol/l
1.71
16
327
109
767
1.38
2.66
1.6
1.5
248.16
257.61
ug/g
0.20
66
489
260
2058
1.23
2.63
1.5
1.6
1.57
1.51
g/l
0.55
213
1735
11
269
0.39
2.63
1.4
1.2
—
—
—
0
0
393
3239
1.19
2.61
2.2
2.3
64.59
65.60
g/l
1.62
322
2843
171
2090
0.78
2.61
2.5
3.6
0.91
0.68
%
0.53
62
778
297
3412
0.83
2.56
1.2
1.3
—
—
—
0
0
468
3930
1.17
2.49
1.2
1.2
2.22
1.53
u/ml
0.34
87
945
16
327
0.47
2.46
1.1
1.2
—
—
—
0
0
15
61
2.38
2.42
1.2
1.2
—
—
—
0
0
203
1585
1.25
2.36
3.2
3.5
5.77
6.15
e9/l
0.12
141
1107
186
2220
0.80
2.35
2.6
3.6
0.05
0.09
%
0.64
63
809
29
156
1.80
2.30
1.8
1.3
—
—
—
0
0
11
38
2.80
2.30
1.6
1.2
—
—
—
0
0
7
180
0.37
2.27
1.9
1.7
—
—
—
0
0
67
446
1.46
2.27
1.5
1.4
—
—
—
0
0
238
1903
1.22
2.23
6.2
6.7
24.59
24.34
mmol/l
0.57
205
1758
152
1160
1.27
2.17
2.0
2.1
35.90
36.32
g/l
0.38
113
968
26
435
0.57
2.16
1.4
1.3
—
—
—
0
0
22
383
0.55
2.11
2.7
3.7
64.03
59.43
%
0.66
16
306
12
47
2.47
2.11
1.6
1.2
—
—
—
0
0
171
2031
0.80
2.10
2.5
3.7
1.00
0.26
%
0.43
48
642
101
733
1.34
2.09
1.3
1.2
—
—
—
0
0
9
199
0.43
2.07
1.0
1.1
—
47.59
—
0
9
281
2303
1.19
2.05
3.3
3.9
7.41
7.41
ph
0.29
35
288
95
687
1.34
2.03
1.5
1.5
17590.96
19069.75
e6/l
0.11
68
487
201
2337
0.82
2.02
2.6
3.6
1.05
0.92
%
0.26
78
923
35
208
1.63
1.99
1.1
1.5
—
—
—
0
0
335
3717
0.86
1.97
2.7
3.6
11.09
22.75
ug/l
0.85
277
3117
6
15
3.86
1.97
1.0
1.0
—
—
—
0
0
749
6597
1.11
1.95
4.7
6.2
—
—
—
0
0
16
75
2.06
1.90
1.1
1.2
—
—
—
0
0
296
3306
0.85
1.90
4.3
4.8
34.75
34.54
%
0.12
202
2108
5
11
4.39
1.88
1.0
1.2
—
—
—
0
0
100
1247
0.77
1.87
1.3
1.2
—
—
—
0
0
6
16
3.62
1.86
1.5
1.1
—
21.40
—
0
5
9
33
2.63
1.84
1.2
1.3
—
—
—
0
0
2369
22023
1.08
1.82
4.1
4.7
4.02
4.24
mmol/l
20.71
2103
19414
59
405
1.41
1.76
1.3
1.2
0.78
0.80
nmol/l
0.04
47
322
220
2498
0.84
1.74
1.3
1.3
—
—
—
0
0
281
2339
1.17
1.74
3.3
3.8
5.27
5.17
kpa
0.99
246
2177
172
1374
1.22
1.70
2.1
2.7
56.95
105.86
mg/l
0.62
136
1120
168
1341
1.22
1.67
2.1
2.7
1.50
3.34
ratio
—
10
100
372
3180
1.14
1.62
5.1
4.7
—
—
—
0
0
6
19
3.05
1.59
1.0
1.2
123.83
126.36
mmol/l
—
6
11
31
191
1.57
1.58
2.5
3.1
8.20
7.45
mmol/l
0.63
23
126
170
1371
1.20
1.55
2.1
2.8
49.94
66.79
mg/l
0.52
133
1121
16
82
1.88
1.53
1.1
1.2
—
—
—
0
0
113
875
1.25
1.52
3.4
3.9
—
—
—
0
0
2329
21732
1.07
1.50
4.0
4.7
1.36
1.42
mmol/l
8.18
2057
18941
192
1572
1.19
1.49
1.4
1.5
—
—
—
0
0
229
1904
1.17
1.48
2.7
2.6
—
—
—
0
0
59
426
1.34
1.36
1.2
1.2
—
—
—
0
0
32
451
0.68
1.36
1.2
1.2
—
—
—
0
0
130
1037
1.22
1.36
2.0
2.8
—
—
—
0
0
41
552
0.71
1.36
2.4
2.7
—
—
—
0
0
16
86
1.80
1.35
2.5
1.8
—
—
—
0
0
150
1713
0.84
1.33
1.5
1.5
—
—
—
0
0
6
23
2.52
1.30
1.3
1.0
—
—
—
0
0
34
225
1.46
1.30
1.5
1.2
—
—
—
0
0
17
272
0.60
1.29
1.1
1.2
—
—
—
0
0
106
833
1.23
1.29
4.5
4.7
2.57
3.04
mmol/l
0.85
78
555
141
1142
1.20
1.27
2.4
2.7
0.55
0.30
g/l
1.05
40
437
862
8835
0.93
1.25
3.0
3.2
923.48
338.23
mg/l
1.84
608
5775
18
278
0.62
1.20
1.0
1.1
—
—
—
0
0
55
403
1.32
1.19
1.5
2.2
1.19
1.33
g/24h
0.14
15
196
12
205
0.56
1.18
1.1
1.1
—
—
—
0
0
35
238
1.42
1.18
1.2
1.5
—
—
—
0
0
118
948
1.21
1.18
4.8
4.5
7.42
7.42
ph
0.38
106
853
28
183
1.48
1.16
1.1
1.2
1.63
5.23
u/ml
—
8
92
14
227
0.59
1.15
1.2
1.1
—
—
—
0
0
867
8855
0.93
1.15
2.9
3.1
6.72
6.59
mmol/l
0.44
698
7084
56
415
1.30
1.13
1.2
1.3
—
—
—
0
0
39
509
0.74
1.11
1.0
1.1
—
—
—
0
0
2245
21051
1.06
1.11
3.7
4.2
1.22
1.23
mmol/l
0.19
1957
18126
8
39
1.98
1.10
1.8
1.6
—
—
—
0
0
5
20
2.41
1.10
1.4
1.3
—
—
—
0
0
92
730
1.22
1.07
4.7
3.9
32.55
31.54
mg/l
0.09
69
501
5
21
2.30
1.04
1.6
1.0
—
—
—
0
0
106
860
1.19
1.00
2.0
2.3
124.98
123.14
g/l
0.27
83
616
228
2459
0.89
0.99
1.2
1.3
517.60
518.39
titre
0.00
50
548
106
1208
0.84
0.99
1.9
2.6
89.31
4834.52
u/ml
1.33
85
1019
7
35
1.93
0.96
3.4
8.6
—
—
—
0
0
1190
10999
1.06
0.95
10.7
10.9
0.00
0.00
e9/l
0.84
879
8796
15
89
1.63
0.95
1.2
1.2
—
—
—
0
0
50
612
0.79
0.93
2.6
3.8
1.59
1.49
%
0.10
38
510
53
405
1.26
0.89
1.3
1.5
3.17
4.31
iu/l
—
10
106
6
28
2.07
0.89
3.8
7.9
—
—
—
0
0
5
101
0.48
0.88
1.2
1.1
—
—
—
0
0
13
76
1.65
0.88
1.2
1.1
27.20
120.05
ng/l
—
5
19
8
42
1.84
0.86
1.3
1.3
2.00
1.06
ug/l
—
8
37
8
43
1.80
0.84
2.1
1.7
135.88
109.40
nmol/24h
—
8
43
11
170
0.62
0.80
1.4
1.2
—
—
—
0
0
0
23
0.00
0.79
0.0
1.0
—
—
—
0
0
31
390
0.76
0.75
2.5
4.3
—
—
—
0
0
187
1623
1.12
0.75
2.7
2.9
—
—
—
0
0
149
1277
1.13
0.74
1.4
1.3
—
—
—
0
0
119
1005
1.15
0.74
1.2
1.3
38.20
66.61
au/ml
—
5
57
60
478
1.21
0.74
1.2
1.1
184.00
84.83
titre
—
5
29
35
262
1.29
0.72
1.0
1.2
—
—
—
0
0
6
106
0.55
0.72
1.7
1.8
—
—
—
0
0
975
9036
1.05
0.72
5.7
4.8
—
—
—
0
0
7
38
1.78
0.72
1.0
1.1
2322.86
1566.68
miu/ml
—
7
38
10
153
0.63
0.71
1.0
1.0
—
—
—
0
0
390
3517
1.08
0.70
1.4
1.5
3.17
2.78
g/l
1.05
198
1929
9
138
0.63
0.69
1.0
1.2
—
—
—
0
0
9
56
1.55
0.69
1.3
1.5
99.44
128.46
ng/l
—
9
56
95
794
1.16
0.69
2.3
2.9
—
—
—
0
0
38
290
1.27
0.69
1.2
1.4
614.29
210.31
titre
—
7
32
19
130
1.41
0.69
2.3
4.1
59.87
55.44
%
0.40
19
120
770
7103
1.05
0.68
6.2
4.9
0.00
0.00
estimate
0.50
202
2236
5
91
0.53
0.66
1.0
1.0
—
—
—
0
0
5
28
1.72
0.63
1.0
1.1
—
—
—
0
0
5
29
1.66
0.61
1.0
1.0
15.46
17.53
umol/l
—
5
24
0
19
0.00
0.60
0.0
1.2
—
—
—
0
0
128
1374
0.90
0.59
1.9
2.0
9.61
10.15
nmol/l
0.24
104
1151
135
1444
0.90
0.59
4.9
4.3
—
—
—
0
0
22
160
1.33
0.58
1.4
1.2
0.33
0.52
g/l
1.59
14
117
22
160
1.33
0.58
1.4
1.2
7.06
7.25
g/l
0.07
14
117
22
160
1.33
0.58
1.4
1.2
2.68
2.86
g/l
0.15
13
119
6
34
1.70
0.57
1.3
1.2
—
—
—
0
0
33
255
1.25
0.57
1.0
1.1
—
—
—
0
0
11
155
0.68
0.56
1.5
1.5
10.88
17.15
%
0.96
11
135
114
983
1.12
0.56
1.3
1.2
—
—
—
0
0
5
84
0.57
0.56
1.0
1.1
—
—
—
0
0
5
84
0.57
0.56
1.0
1.1
—
—
—
0
0
14
95
1.42
0.55
1.2
1.9
1.14
0.66
mmol/l
0.18
14
87
185
1640
1.09
0.54
3.4
3.9
—
—
—
0
0
22
163
1.30
0.52
1.4
1.2
—
—
—
0
0
12
80
1.45
0.51
1.4
1.2
231.08
224.10
iu/ml
0.02
12
80
808
7526
1.04
0.50
2.6
3.0
5010.27
7874.70
umol/l
0.99
664
6206
10
65
1.48
0.48
2.7
2.2
—
—
—
0
0
21
258
0.78
0.48
1.6
1.3
26.21
23.04
%
0.19
16
164
7
45
1.50
0.47
1.6
1.6
—
—
—
0
0
36
290
1.20
0.45
1.8
2.2
661.73
618.67
ml
0.20
22
165
184
1648
1.08
0.45
2.3
2.6
11.18
11.05
g/l
0.10
162
1467
55
608
0.87
0.44
1.3
1.4
—
—
—
0
0
22
168
1.26
0.44
1.0
1.1
—
31.86
—
0
7
53
585
0.87
0.42
1.4
1.6
15.26
13.55
mg/l
0.49
47
525
25
295
0.82
0.42
1.2
1.1
—
—
—
0
0
64
545
1.13
0.42
1.4
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
955
9453
0.97
0.41
3.4
3.8
14.61
10.58
mg/mmol
1.45
645
6046
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
101
1068
0.91
0.40
2.7
2.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.14
—
0
7
146
1306
1.08
0.39
3.2
3.5
1.43
1.48
mmol/l
0.28
141
1281
152
1362
1.08
0.39
4.0
4.3
25.13
24.75
mmol/l
0.71
117
1220
34
278
1.18
0.38
1.0
1.0
—
—
—
0
0
15
112
1.29
0.36
1.7
2.0
—
—
—
0
0
15
112
1.29
0.36
1.9
2.6
33.33
34.20
%
—
9
69
33
271
1.18
0.36
1.8
1.4
0.68
0.90
g/l
1.13
25
204
46
504
0.88
0.35
3.2
2.9
—
—
—
0
0
25
288
0.84
0.35
1.0
1.1
—
—
—
0
0
9
118
0.73
0.35
1.7
1.9
670.33
590.68
e6/l
—
9
107
12
87
1.33
0.35
4.3
5.5
—
—
—
0
0
233
2133
1.06
0.34
7.0
6.8
0.64
0.67
%
0.53
228
2115
14
171
0.79
0.33
1.1
1.1
—
127.14
—
0
7
68
724
0.90
0.33
3.8
2.9
—
—
—
0
0
45
491
0.88
0.33
2.9
1.9
32.98
32.25
pg
0.55
45
485
233
2140
1.05
0.31
6.9
6.7
1.39
1.32
%
0.75
227
2120
66
578
1.10
0.30
1.3
1.5
—
—
—
0
0
14
107
1.26
0.30
2.1
2.9
—
—
—
0
0
22
251
0.84
0.29
1.1
1.3
—
—
—
0
0
77
806
0.92
0.28
1.8
2.2
250.71
91.28
ug/min
0.76
38
470
72
638
1.09
0.27
2.9
1.9
—
—
—
0
0
32
351
0.88
0.27
1.1
1.2
—
—
—
0
0
13
155
0.81
0.26
1.3
1.3
2.38
3.36
mmol/l
2.01
13
139
78
695
1.08
0.26
2.1
2.4
1.89
1.92
mg/l
0.10
66
600
49
522
0.90
0.26
4.1
3.2
63.39
61.13
%
0.54
49
522
9
72
1.21
0.25
1.1
1.1
—
32.56
pmol/l
—
0
8
19
214
0.86
0.23
1.4
2.0
—
—
—
0
0
7
90
0.75
0.22
1.7
1.1
5.80
6.52
mmol/l
—
7
85
82
844
0.94
0.22
1.1
1.1
57.44
103.88
iu/ml
1.19
19
274
54
479
1.09
0.21
2.0
2.3
29.90
26.09
mg/l
0.17
21
112
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
29
249
1.12
0.20
1.7
1.4
—
—
—
0
0
0
13
0.00
0.20
0.0
1.1
—
225.62
—
0
13
19
210
0.87
0.19
1.3
1.5
76.09
70.19
%
0.35
11
168
64
576
1.07
0.19
1.3
1.3
1.21
1.13
g/l
1.09
58
535
33
351
0.91
0.19
2.2
2.7
—
—
—
0
0
568
5584
0.98
0.19
1.2
1.3
—
—
—
0
0
6
51
1.13
0.18
1.0
1.1
—
—
—
0
0
18
199
0.87
0.18
1.1
1.2
—
—
—
0
0
5
67
0.72
0.16
1.8
1.3
20.32
30.29
g/l
—
5
52
31
328
0.91
0.16
1.2
1.1
—
—
—
0
0
62
562
1.06
0.16
1.2
1.3
0.27
0.23
g/l
2.14
56
523
14
116
1.16
0.16
1.9
2.5
1833.33
1803.98
ml
—
9
88
6
75
0.77
0.15
1.3
1.7
6.67
8.85
%
—
6
68
44
395
1.07
0.15
1.4
1.8
—
—
—
0
0
24
209
1.11
0.14
1.3
1.3
—
—
—
0
0
19
205
0.89
0.14
1.4
2.1
—
—
—
0
0
8
94
0.82
0.13
4.6
6.2
—
—
—
0
0
8
96
0.80
0.13
1.0
1.0
—
—
—
0
0
8
97
0.79
0.13
2.4
2.0
—
—
—
0
0
18
194
0.89
0.13
2.8
2.6
—
—
—
0
0
9
104
0.83
0.13
1.0
1.0
—
—
—
0
0
28
293
0.92
0.13
1.1
1.3
—
—
—
0
0
51
520
0.94
0.12
1.4
1.5
—
—
—
0
0
16
172
0.90
0.11
1.4
1.4
—
—
—
0
0
28
250
1.08
0.11
1.2
1.1
290.13
316.14
u/ml
0.15
16
140
206
2032
0.98
0.11
1.8
1.8
245.03
175.08
ug/g
1.10
164
1560
30
310
0.93
0.10
1.4
1.2
—
—
—
0
0
22
195
1.09
0.10
2.0
2.0
2.02
1.96
ug/l
0.04
17
157
5
43
1.12
0.10
1.2
1.1
—
—
—
0
0
18
158
1.10
0.09
1.4
1.3
—
—
—
0
0
11
93
1.14
0.09
1.6
1.6
92.73
117.73
ug/l
0.45
11
82
61
613
0.96
0.09
1.3
1.5
109211.16
71323.20
e6/l
0.29
38
366
10
110
0.88
0.09
1.3
1.7
0.07
0.72
e9/l
—
10
100
11
120
0.88
0.09
1.3
1.3
—
—
—
0
0
282
2674
1.02
0.09
1.4
1.4
—
—
—
0
0
237
2327
0.98
0.09
6.2
4.8
—
—
—
0
0
23
239
0.93
0.09
1.0
1.3
—
—
nmol/l
—
0
0
29
262
1.07
0.09
1.3
1.3
107855.36
145995.43
e6/l
0.16
14
176
50
504
0.96
0.09
2.4
2.3
—
—
—
0
0
13
139
0.90
0.08
4.1
4.4
—
—
—
0
0
283
2688
1.02
0.08
4.1
3.8
—
—
—
0
0
7
62
1.09
0.08
1.3
1.2
—
—
—
0
0
81
805
0.97
0.08
14.1
14.1
—
—
—
0
0
7
64
1.05
0.08
1.1
1.2
—
—
—
0
0
6
68
0.85
0.07
1.3
1.8
—
—
—
0
0
8
72
1.07
0.07
1.1
1.6
—
—
—
0
0
222
2108
1.02
0.07
7.3
6.9
91.59
93.82
%
2.37
222
2096
58
577
0.97
0.06
1.3
1.2
67.82
48.48
u/l
0.22
51
489
87
859
0.98
0.06
1.4
1.2
288.10
244.02
u/ml
0.21
75
765
656
6285
1.01
0.05
2.9
3.4
0.80
0.91
ug/l
2.67
480
4631
26
260
0.96
0.03
1.4
1.3
116.58
117.64
u/ml
—
8
46
59
580
0.98
0.03
1.4
1.6
—
—
—
0
0
140
1336
1.01
0.03
1.4
1.8
1.13
1.50
g/l
1.20
120
1171
38
376
0.97
0.02
1.4
1.4
—
—
—
0
0
37
366
0.97
0.02
1.5
1.4
3.65
3.93
mmol/24h
0.19
28
304
78
763
0.99
0.02
1.3
1.5
27.93
29.83
g/l
0.82
66
659
74
704
1.01
0.02
1.8
1.6
—
—
—
0
0
12
109
1.06
0.01
1.2
1.1
37.38
39.09
g/l
—
5
46
11
104
1.02
0.00
1.1
1.1
—
—
—
0
0
16
153
1.01
0.00
1.1
1.3
83.67
67.93
mg/l
—
6
101
37
354
1.01
0.00
1.4
1.4
66.18
67.26
%
0.06
28
228
85
817
1.00
0.00
2.6
2.6
15.42
15.21
%
0.16
44
425
69
666
1.00
0.00
1.3
1.5
2969.05
1404.91
e6/l
0.71
44
480
20
198
0.97
0.00
1.7
2.0
522.20
497.62
min
0.58
15
126
11
106
1.00
0.00
2.2
2.2
—
—
—
0
0
20
196
0.98
0.00
1.9
2.1
1224.00
83.33
ug/min
—
5
51
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
59
0.98
-0.00
3.2
2.3
—
—
—
0
0
7
70
0.96
-0.00
1.3
2.6
13.51
14.23
ml/dl
—
7
64
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
269.44
—
0
9
5
57
0.85
-0.00
1.2
2.0
—
—
—
0
0
8
80
0.96
-0.00
1.8
1.3
18.46
22.81
umol/l
—
8
74
8
84
0.92
-0.00
1.1
1.3
—
0.44
g/l
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
70
0.96
-0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
83
0.93
-0.00
1.4
1.2
—
—
—
0
0
8
78
0.99
-0.00
1.0
1.2
191.38
142.37
mmol/24h
—
8
78
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
52
0.93
-0.00
1.4
1.2
—
—
—
0
0
5
53
0.91
-0.00
1.0
1.0
—
3.12
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
1638.00
—
0
5
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_VASCDEM and mortality.

Females

Parameter HR [95% CI] p-value
F5_VASCDEM 2.669 [2.37, 3.01] < 0.001
Birth year 0.995 [0.99, 1.0] 0.188

During the follow-up period (1.1.1998 — 31.12.2019), 15971 out of 21397 females with F5_VASCDEM died.

Males

Parameter HR [95% CI] p-value
F5_VASCDEM 3.066 [2.63, 3.58] < 0.001
Birth year 0.989 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 11786 out of 15677 males with F5_VASCDEM died.

Mortality risk

Mortality risk for people of age

years, who have F5_VASCDEM.

N-year risk Females Males
1 0.181% 0.66%
5 1.301% 3.649%
10 3.382% 8.705%
15 6.703% 15.866%
20 11.875% 26.392%

Relationships between endpoints

Index endpoint: F5_VASCDEM – Vascular dementia

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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