No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
663 |
4. Check minimum number of eventsNone |
663 |
5. Include endpointsNone |
663 |
6. Filter based on genotype QC (FinnGen only) |
649 |
Control definitions (FinnGen only)
- Control exclude
- F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F01
- Name in latin
- Dementia e multis infarctibus
Similar endpoints
↥List of similar endpoints to
Vascular dementia (multiple infarctions)
based on the number of shared cases.
Similar with more cases:
- Vascular dementia
- Dementia
- Dementia, including avohilmo
- Organic, including symptomatic, mental disorders
- Psychiatric diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 649 | 195 | 454 |
| Unadjusted period prevalence (%) | 0.17 | 0.07 | 0.21 |
| Median age at first event (years) | 77.15 | 79.14 | 76.30 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 662
- Matched controls
- 6610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F03
ICD-10 Finland
Unspecified dementia
71.1
292.9
162
30
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
291.8
258
*
F01.1
ICD-10 Finland
Multi-infarct dementia
+∞
231.1
208
*
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
+∞
215.7
195
*
N06DX01
ATC
memantine; oral
60.7
182.5
103
20
F01.9
ICD-10 Finland
Vascular dementia, unspecified
300.1
163.3
160
7
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
7.5
134.7
264
539
N06DA02
ATC
donepezil; oral
51.8
134.2
78
17
N05AX08
ATC
risperidone; systemic
10.1
112.2
143
176
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
80.9
76
*
N05AH04
ATC
quetiapine; oral
6.6
78.5
147
275
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
4.5
74.0
257
814
G30.1
ICD-10 Finland
Alzheimer disease with late onset
89.6
65.4
72
9
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
607.4
57.5
56
*
4378A
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Other[MULTI-INFARKTIDEMENTIA]
+∞
53.9
51
*
F01.0
ICD-10 Finland
Vascular dementia of acute onset
+∞
48.5
46
*
F01.14
ICD-10 Finland
Multi-infarct dementia's other mixed symptoms of mixed type
+∞
48.5
46
*
N06DA03
ATC
rivastigmine; oral, transdermal
93.8
47.6
52
6
N03AG01
ATC
valproic acid; systemic, rectal
8.5
46.6
63
81
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
5.2
46.0
106
235
G30.8
ICD-10 Finland
Other Alzheimer disease
120.3
42.3
45
*
R41.0
ICD-10 Finland
Disorientation, unspecified
7.5
41.7
63
92
4378X
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Other[MORBUS CERBROVASCULARIS ALIA DEFINITA]
+∞
38.9
37
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.0
37.7
126
371
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
65.4
37.6
43
7
N05AD03
ATC
melperone; systemic
7.4
36.9
56
82
N06AB04
ATC
citalopram; systemic
3.2
36.9
189
732
P70
ICPC
Dementia
11.1
35.1
38
36
Z75.5
ICD-10 Finland
Holiday relief care
8.9
33.8
43
51
N05AD01
ATC
haloperidol; systemic
5.3
33.5
72
149
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
66.9
33.4
38
6
N06DA04
ATC
galantamine; oral
122.8
33.0
35
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.8
31.5
60
111
B01AC07
ATC
dipyridamole; systemic
3.2
31.5
154
576
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.7
27.0
66
152
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
145.7
26.8
28
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.7
26.7
92
274
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.1
26.6
48
84
P20
ICPC
Memory disturbance
3.0
24.6
123
461
F01.11
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly paranoidism
+∞
24.1
23
*
R53
ICD-10 Finland
Malaise and fatigue
2.5
23.5
188
897
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
6.9
20.5
32
48
N03AF02
ATC
oxcarbazepine; oral
6.6
20.2
33
52
N05AH03
ATC
olanzapine; systemic
6.5
19.4
32
51
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
18.3
299
1880
F01
ICD-10 Finland
Vascular dementia
97.6
17.6
19
*
F01.12
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly hallucinations
+∞
16.7
16
*
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
16.7
16
*
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
16.7
16
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.7
16.6
100
410
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
173.9
16.6
17
*
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
173.9
16.6
17
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.9
15.9
49
134
F01.13
ICD-10 Finland
The other additional symptoms of multi-infarct dementia, mainly depression
+∞
15.7
15
*
N05BA04
ATC
oxazepam; oral
2.1
14.8
172
940
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
+∞
14.6
14
*
A06AD11
ATC
lactulose; oral
2.0
14.2
186
1061
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.6
13.7
22
34
N05BA06
ATC
lorazepam; systemic, sublingual
3.2
13.6
55
180
F0019, G301,
ICD-10 Finland
+∞
13.6
13
*
H53.4
ICD-10 Finland
Visual field defects
5.4
13.5
27
52
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.1
13.5
37
93
F05.1
ICD-10 Finland
Delirium superimposed on dementia
29.0
13.0
17
6
K90
ICPC
Stroke/cerebrovascular accident
3.9
12.9
38
101
N06AX11
ATC
mirtazapine; oral
2.0
12.8
173
992
F05.9
ICD-10 Finland
Delirium, unspecified
4.3
12.6
33
80
G30
ICD-10 Finland
Alzheimer disease
+∞
12.5
12
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.9
12.3
22
38
TAB00
NOMESCO Finland
Lumbar puncture
5.8
12.0
22
39
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.3
12.0
46
146
N06AB10
ATC
escitalopram; oral
2.6
11.8
74
308
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
11.8
236
1533
F06.7
ICD-10 Finland
Mild cognitive disorder
4.4
11.8
30
71
AA1AD
NOMESCO Finland
CT of head and brain
1.9
11.6
183
1103
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.1
11.5
50
171
F01.2
ICD-10 Finland
Subcortical vascular dementia
35.6
11.3
14
*
Z2445
NOMESCO Finland
Psychologist
9.0
10.8
22
25
SPAT1053
SPAT
Memory test
2.1
10.7
114
597
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.0
10.6
48
168
A28
ICPC
Limited function/disability NOS
1.9
10.4
151
881
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
10.2
127
702
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.8
10.1
53
202
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
3.1
9.7
41
138
S01.0
ICD-10 Finland
Open wound of scalp
2.5
8.9
60
258
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
8.9
121
688
N30.0
ICD-10 Finland
Acute cystitis
2.1
8.9
89
454
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
8.7
45
1028
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.8
8.6
42
154
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.8
8.4
41
150
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
3.4
8.4
30
91
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.7
8.4
47
185
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
4.5
8.4
20
45
F009, G309,
ICD-10 Finland
+∞
8.3
8
*
XA800
NOMESCO Finland
Neuropsychological investigation
7.2
8.3
19
27
A10AB05
ATC
insulin aspart; parenteral
2.5
8.1
54
231
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
4.2
8.0
21
51
315
Kela drug reimbursment
Clopidogrel
3.8
7.9
24
65
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
7.9
120
707
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.6
154
985
N05CD07
ATC
temazepam; oral
1.8
7.6
145
912
N05AB03
ATC
perphenazine; systemic, rectal
3.7
7.6
24
67
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.9
7.6
36
130
130
Kela drug reimbursment
Malignant tumour
0.2
7.3
12
501
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.2
7.2
62
297
R55
ICD-10 Finland
Syncope and collapse
1.9
7.2
93
518
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.7
7.1
17
26
I95.1
ICD-10 Finland
Orthostatic hypotension
2.5
6.9
45
191
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
7.3
6.7
15
21
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.6
6.6
38
152
G04BD07
ATC
tolterodine; oral
2.2
6.6
53
248
K91
ICPC
Cerebrovascular disease
5.4
6.5
18
34
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.0
6.5
28
96
F01.39
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without information on additional symptoms
70.4
6.4
7
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.1
6.4
65
333
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
4.1
6.4
17
42
N06AB06
ATC
sertraline; oral
2.5
6.4
38
155
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.5
6.4
38
155
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
11.1
6.3
11
10
SPAT1216
SPAT
Assessment of functional ability
1.8
6.3
105
634
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
6.3
6
*
F01.24
ICD-10 Finland
Subcortical vascular dementia other additional symptoms of mixed type
+∞
6.3
6
*
F05.8
ICD-10 Finland
Other delirium
7.1
6.2
14
20
WYA20
NOMESCO Finland
Home visit
3.7
6.2
19
52
Z02.7
ICD-10 Finland
Issue of medical certificate
2.5
6.1
39
164
S06.0
ICD-10 Finland
Concussion
2.1
6.1
56
276
SPAT1229
SPAT
Assessment of need for aid
2.1
6.1
54
263
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.0
6.1
67
354
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
132
852
1.68
6.23
2.0
1.8
1016.56
1180.30
nmol/l
1.51
105
632
198
2604
0.66
5.67
4.4
4.5
3.87
4.18
mmol/l
4.38
183
2300
210
2713
0.67
5.42
4.9
5.1
2.13
2.37
mmol/l
4.68
196
2362
202
2622
0.67
5.30
23.6
19.5
65.86
65.31
ml/min/173m2
0.13
166
2196
197
2568
0.67
5.28
4.3
4.5
1.28
1.37
mmol/l
2.49
182
2229
214
2736
0.68
5.14
5.0
5.1
6.26
6.22
mmol/l
0.14
183
2360
30
632
0.45
4.61
1.5
1.6
1.13
1.22
mmol/l
0.50
25
508
195
2484
0.69
4.36
4.0
4.1
1.23
1.23
mmol/l
0.01
178
2145
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
6
11.75
4.28
1.3
1.2
—
—
—
0
0
185
2371
0.69
4.25
30.6
23.0
15.94
15.50
%
0.47
179
2302
67
404
1.73
4.04
2.9
2.6
4.16
6.41
ug/l
1.57
55
347
214
2651
0.71
3.95
7.5
6.7
45.67
42.17
mmol/mol
2.75
191
2359
144
1054
1.47
3.81
2.5
2.0
235.24
235.05
u/l
0.00
132
970
30
142
2.16
3.69
2.0
1.7
—
—
—
0
0
53
865
0.58
3.65
2.9
3.3
0.87
0.95
ug/l
0.28
39
621
250
2987
0.74
3.54
11.3
10.5
27.36
24.39
u/l
0.37
231
2817
116
1555
0.69
3.25
4.4
5.7
2.54
8.86
ug/l
1.50
94
1346
7
11
6.41
3.19
1.4
1.0
—
—
—
0
0
7
12
5.87
3.02
1.4
1.0
—
—
—
0
0
6
9
6.70
2.87
1.2
1.0
—
—
—
0
0
30
163
1.88
2.61
2.1
1.9
—
—
—
0
0
5
7
7.18
2.55
2.0
1.1
2.00
1.81
mmol/l
—
5
7
35
577
0.58
2.52
3.5
2.6
19.19
21.16
%
0.44
26
509
43
670
0.62
2.48
3.1
2.5
9.96
11.44
umol/l
1.35
37
614
5
8
6.28
2.37
1.0
1.1
—
—
—
0
0
182
2181
0.77
2.34
3.9
4.0
17.72
17.19
mm/h
0.13
162
1950
9
219
0.40
2.34
1.2
1.3
—
—
—
0
0
273
3112
0.79
2.33
36.3
28.4
4.20
4.27
e12/l
1.38
251
2973
273
3112
0.79
2.33
36.8
28.5
36.69
38.09
%
1.60
224
2821
273
3111
0.79
2.32
36.5
28.3
242.59
230.47
e9/l
1.89
256
2980
39
240
1.66
2.27
1.5
1.5
—
—
—
0
0
94
1233
0.72
2.26
4.6
4.8
22.50
22.32
%
0.04
54
660
274
3112
0.79
2.23
36.5
28.6
126.36
129.03
g/l
1.96
258
3012
271
3081
0.79
2.23
32.3
24.1
3.99
4.05
mmol/l
2.17
250
2964
92
685
1.40
2.21
2.2
1.8
—
—
—
0
0
271
3078
0.80
2.20
32.3
23.9
139.71
139.30
mmol/l
1.43
252
2961
18
345
0.51
2.19
1.2
1.2
74.74
45.60
iu/ml
—
5
114
45
663
0.65
2.04
2.2
1.6
1.15
1.44
mg/l
0.80
37
526
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
166
1.71
1.89
1.8
2.1
0.27
0.37
u/ml
0.70
17
94
79
590
1.38
1.88
1.9
2.0
29.38
30.34
s
0.87
74
575
85
1094
0.74
1.80
4.7
3.7
0.76
0.56
e6/l
0.33
76
880
84
1066
0.76
1.62
3.7
3.6
18.26
11.68
mg/mmol
0.66
55
695
69
901
0.74
1.62
2.6
2.9
6187.85
8184.02
umol/l
0.13
55
736
34
224
1.54
1.56
4.7
3.2
24.81
24.83
mmol/l
0.01
34
216
7
27
2.61
1.51
1.4
1.4
—
—
—
0
0
119
1427
0.80
1.46
4.8
5.4
21.07
23.91
%
2.04
109
1316
36
510
0.69
1.39
2.7
3.1
221.19
246.64
u/l
1.67
31
477
5
17
2.95
1.36
1.0
1.2
—
—
—
0
0
0
37
0.00
1.34
0.0
1.1
—
—
—
0
0
117
1392
0.80
1.34
5.2
5.2
63.71
60.32
%
2.12
107
1286
0
39
0.00
1.34
0.0
1.6
—
2.29
—
0
33
6
25
2.41
1.24
1.5
1.2
—
—
—
0
0
6
25
2.41
1.24
1.5
1.2
—
—
—
0
0
228
2528
0.85
1.22
4.6
4.4
2.00
2.12
mu/l
0.80
208
2190
126
1469
0.82
1.18
2.9
3.4
2304.84
2809.93
ng/l
0.57
108
1293
22
141
1.58
1.18
1.4
1.2
—
—
—
0
0
27
387
0.68
1.14
1.7
2.7
7.21
11.91
umol/l
1.42
19
332
41
302
1.38
1.13
2.0
1.6
—
—
—
0
0
62
488
1.30
1.11
5.8
5.9
1.31
1.27
mmol/l
0.02
42
358
7
32
2.20
1.08
1.3
1.6
—
—
—
0
0
10
179
0.55
1.07
3.8
2.1
—
—
—
0
0
6
122
0.49
1.06
1.7
1.4
—
—
—
0
0
51
394
1.32
1.05
14.8
10.0
—
—
—
0
0
61
485
1.28
1.02
5.9
5.9
4.95
5.04
kpa
0.30
54
449
61
486
1.28
1.01
5.9
5.9
10.85
11.08
kpa
0.19
54
452
154
1737
0.85
1.00
6.2
7.9
5.21
4.56
e9/l
1.68
130
1484
272
2938
0.87
0.98
27.3
19.7
31.90
30.23
mg/l
0.34
244
2498
60
480
1.27
0.97
1.9
1.7
—
—
—
0
0
223
2437
0.87
0.94
6.6
7.0
84.77
85.79
u/l
0.11
200
2245
6
27
2.23
0.93
1.5
1.4
—
—
—
0
0
218
1985
1.14
0.88
27.7
23.4
1.53
1.51
inr
0.08
58
562
113
1293
0.85
0.87
2.7
2.8
139.71
170.22
ug/l
0.89
97
1150
52
415
1.27
0.87
3.7
3.5
2.31
1.91
mmol/l
0.44
44
323
27
363
0.73
0.83
4.7
4.7
33.29
33.39
%
0.02
21
224
180
1981
0.87
0.83
3.5
3.5
14.71
15.20
pmol/l
1.59
156
1724
59
482
1.24
0.82
2.1
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
0
25
0.00
0.79
0.0
3.7
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
—
—
0
0
9
53
1.70
0.75
1.4
1.2
—
—
—
0
0
94
813
1.18
0.75
1.6
1.8
463.14
8796729.76
pmol/l
0.50
73
648
79
673
1.20
0.75
6.5
5.1
1.02
1.01
kg/l
0.30
13
110
9
56
1.61
0.72
2.4
1.5
—
—
—
0
0
5
26
1.93
0.70
1.0
1.5
—
—
—
0
0
5
26
1.93
0.70
1.0
1.5
—
—
—
0
0
5
26
1.93
0.70
1.0
1.5
—
—
—
0
0
81
699
1.18
0.68
2.8
3.3
2.45
2.47
mmol/l
0.75
64
591
5
28
1.79
0.66
1.2
1.0
—
—
—
0
0
8
49
1.64
0.62
1.3
1.2
—
—
—
0
0
124
1114
1.14
0.62
2.7
3.2
2.33
2.34
mmol/l
0.31
102
957
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
161
1748
0.89
0.59
4.7
5.5
11.28
13.69
umol/l
2.33
148
1641
124
1122
1.13
0.56
2.1
2.1
70.04
79.01
nmol/l
3.62
98
964
24
302
0.79
0.51
5.8
3.7
1.20
1.21
mmol/l
0.62
18
257
164
1520
1.10
0.49
5.3
4.7
47.16
72.96
ng/l
0.92
131
1216
111
1008
1.12
0.48
2.5
2.3
48.55
60.46
u/l
1.65
104
930
161
1493
1.10
0.48
2.6
2.1
85.95
91.06
pmol/l
0.81
104
801
56
486
1.16
0.47
6.8
6.6
105.84
104.18
mmol/l
1.78
56
486
63
552
1.15
0.47
2.2
2.8
0.81
0.82
mmol/l
0.17
54
506
127
1377
0.90
0.46
4.3
3.7
—
—
—
0
0
9
127
0.70
0.43
1.6
1.5
—
—
—
0
0
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
163
1522
1.09
0.42
4.8
4.5
34.08
33.57
g/l
0.57
150
1396
5
33
1.52
0.41
1.8
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
5
35
1.43
0.39
1.6
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
35
405
0.86
0.36
5.8
4.2
—
—
—
0
0
6
42
1.43
0.35
1.0
1.4
—
—
—
0
0
6
42
1.43
0.35
1.0
1.4
—
—
—
0
0
150
1577
0.94
0.28
6.8
5.6
1.19
1.20
mmol/l
1.00
130
1398
58
634
0.91
0.27
3.2
3.2
1.91
1.32
e6/l
0.70
36
389
56
611
0.91
0.26
3.3
3.4
1.97
1.98
e6/l
0.00
34
369
138
1449
0.94
0.26
2.5
2.9
—
—
—
0
0
124
1172
1.07
0.25
2.4
2.1
—
—
—
0
0
159
1524
1.05
0.22
4.0
2.9
49.75
59.98
u/l
1.41
143
1367
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
56.67
—
0
10
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
111
1058
1.06
0.19
2.3
2.2
2.96
3.30
mg/l
0.59
91
896
14
119
1.18
0.17
1.6
1.4
—
—
—
0
0
14
119
1.18
0.17
1.6
1.4
—
—
—
0
0
11
131
0.84
0.17
3.4
3.5
—
2.72
—
0
13
7
63
1.11
0.17
1.0
1.4
—
—
—
0
0
5
67
0.74
0.17
1.4
1.3
—
—
—
0
0
21
186
1.13
0.16
2.0
1.7
0.65
2.56
ug/l
0.64
14
157
8
73
1.10
0.15
1.4
1.4
—
—
—
0
0
6
76
0.79
0.15
2.7
2.2
3.42
3.63
g/l
—
6
69
82
857
0.95
0.14
6.7
4.7
0.00
0.00
estimate
—
9
282
7
87
0.80
0.14
1.1
1.2
—
—
—
0
0
29
266
1.09
0.13
2.9
3.9
102.24
105.13
ng/l
0.05
21
231
8
100
0.80
0.13
1.9
1.4
—
—
—
0
0
35
376
0.93
0.13
6.4
6.0
10.81
13.88
mmol/l
1.60
29
349
206
2010
1.03
0.13
6.3
4.6
7.53
7.00
mmol/l
1.62
193
1893
84
805
1.05
0.13
6.7
4.1
107.61
296.22
ng/l
1.49
76
726
12
104
1.15
0.12
2.7
4.5
13.86
33.26
mg/l
—
7
72
17
152
1.12
0.12
2.7
2.7
—
—
—
0
0
28
259
1.08
0.11
3.1
3.4
43.67
54.22
ml/min/173m2
—
9
129
87
898
0.96
0.10
2.0
1.6
16.98
19.56
nmol/l
0.84
77
754
5
64
0.78
0.08
1.6
1.4
—
—
—
0
0
7
64
1.09
0.08
1.3
1.3
—
—
—
0
0
6
71
0.84
0.07
1.5
1.4
—
—
—
0
0
7
85
0.82
0.07
1.0
1.0
—
—
—
0
0
9
100
0.90
0.06
1.1
1.3
—
—
—
0
0
35
365
0.96
0.06
2.3
2.4
63.73
65.34
g/l
0.66
28
326
21
223
0.94
0.06
8.3
7.9
23.79
24.62
mmol/l
0.42
15
207
149
1511
0.98
0.06
5.8
4.6
0.00
0.00
estimate
-0.00
22
344
148
1499
0.98
0.05
7.9
6.2
0.00
0.00
estimate
-0.00
17
305
79
804
0.98
0.04
2.3
2.5
—
—
—
0
0
90
890
1.01
0.01
3.0
2.7
51.50
38.14
u/l
0.37
82
853
174
1729
1.01
0.01
7.3
6.3
1.20
1.21
mmol/l
0.03
145
1419
118
1179
1.00
0.00
6.8
5.0
—
—
—
0
0
152
1514
1.00
0.00
5.7
4.6
0.00
0.00
estimate
-0.00
14
295
51
504
1.01
0.00
5.5
4.8
1.02
1.05
mmol/l
0.41
43
467
25
253
0.99
0.00
1.6
1.6
—
—
—
0
0
14
144
0.97
0.00
5.9
4.7
25.45
24.54
mmol/l
0.69
14
138
5
49
1.02
0.00
1.2
1.3
—
—
—
0
0
5
53
0.94
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.8
—
7.05
—
0
6
6
65
0.92
-0.00
1.3
1.1
7.82
53.23
u/l
—
6
59
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
98
0.92
-0.00
1.2
1.5
—
126.67
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
8.39
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.1
—
23.34
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.5
—
13.95
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.0
—
118.11
—
0
9
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: VD_MI – Vascular dementia (multiple infarctions)
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).