vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
713 |
4. Check minimum number of eventsNone |
713 |
5. Include endpointsNone |
713 |
6. Filter based on genotype QC (FinnGen only) |
694 |
Control definitions (FinnGen only)
- Control exclude
- F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F01
- Name in latin
- Dementia vascularis corticalis et subcorticalis mixta
Similar endpoints
↥List of similar endpoints to
Vascular dementia (mixed)
based on the number of shared cases.
Similar with more cases:
- Vascular dementia
- Any dementia
- Any dementia, excluding more controls
- Dementia
- Dementia, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 694 | 263 | 431 |
| Unadjusted period prevalence (%) | 0.16 | 0.09 | 0.20 |
| Median age at first event (years) | 81.92 | 82.65 | 81.47 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 713
- Matched controls
- 7130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06DX01
ATC
memantine; oral
134.3
307.7
241
27
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
955.5
307.7
350
7
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
3657.6
286.4
257
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
103.8
260.4
135
16
F03
ICD-10 Finland
Unspecified dementia
58.1
258.6
148
32
N06DA02
ATC
donepezil; oral
64.6
236.3
132
25
N06DA03
ATC
rivastigmine; oral, transdermal
135.5
226.6
114
10
N05AX08
ATC
risperidone; systemic
13.1
181.0
199
205
P20
ICPC
Memory disturbance
7.2
142.4
299
654
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
7.4
137.7
261
513
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
8.5
134.7
209
330
F01.39
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without information on additional symptoms
1496.6
131.6
124
*
A28
ICPC
Limited function/disability NOS
4.7
90.1
345
1196
F01.9
ICD-10 Finland
Vascular dementia, unspecified
169.1
86.2
89
6
F01.34
ICD-10 Finland
Mixed cortical and subcortical vascular dementia are other mixed symptoms of mixed type
910.3
84.3
81
*
R41.0
ICD-10 Finland
Disorientation, unspecified
9.8
79.3
98
114
N06DA04
ATC
galantamine; oral
221.7
77.9
79
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
4.2
69.2
251
811
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
359.0
66.7
66
*
N05AH04
ATC
quetiapine; oral
5.3
65.8
155
355
AA1AD
NOMESCO Finland
CT of head and brain
3.6
63.1
361
1570
G30.8
ICD-10 Finland
Other Alzheimer disease
172.4
61.0
63
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
60.3
311
1258
SPAT1053
SPAT
Memory test
3.9
59.5
244
848
P70
ICPC
Dementia
15.9
59.3
52
35
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
53.8
51
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.1
49.0
360
1752
R53
ICD-10 Finland
Malaise and fatigue
3.2
46.9
271
1143
F05.9
ICD-10 Finland
Delirium, unspecified
7.8
42.1
61
85
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.7
41.3
160
522
L28
ICPC
Limited function/disability (L)
3.0
41.0
250
1075
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
62.7
40.8
47
8
F01.33
ICD-10 Finland
Mixed cortical and subcortical vascular dementia other additional symptoms, mainly depression
+∞
38.9
37
*
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
10.3
37.8
43
44
N03AG01
ATC
valproic acid; systemic, rectal
6.7
37.4
62
100
R1250
NOMESCO Finland
Evaluation of functional capability
11.4
36.7
39
36
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
54.2
34.8
41
8
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
126.2
34.0
36
*
SPAT1216
SPAT
Assessment of functional ability
2.9
33.3
212
918
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.6
32.7
126
406
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
32.6
206
888
K90
ICPC
Stroke/cerebrovascular accident
5.6
32.5
65
126
F01.32
ICD-10 Finland
Mixed cortical and subcortical vascular dementia other additional symptoms, mainly hallucinations
+∞
31.5
30
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
86.5
30.0
33
*
OAB41
NOMESCO Finland
Guidance and counselling related to ageing
107.9
28.9
31
*
OAB76
NOMESCO Finland
General guidance on nutrition and food
156.3
28.9
30
*
IHZ08
NOMESCO Finland
Provision of support and information for patient’s relatives
156.3
28.9
30
*
F01.31
ICD-10 Finland
Mixed cortical and subcortical vascular dementia other additional symptoms, mainly paranoidism
+∞
28.3
27
*
N06AX11
ATC
mirtazapine; oral
2.5
28.3
265
1372
W0A10
NOMESCO Finland
Mapping of psychosocial situation
104.3
27.9
30
*
AXX01
NOMESCO Finland
Memory assessment
104.3
27.9
30
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.8
27.7
91
262
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
3.3
27.4
116
395
XA800
NOMESCO Finland
Neuropsychological investigation
9.3
27.0
33
37
A04
ICPC
Weakness/tiredness general
2.8
26.9
165
693
N05AH03
ATC
olanzapine; systemic
6.7
26.4
43
68
K91
ICPC
Cerebrovascular disease
8.3
26.2
35
44
N05BA04
ATC
oxazepam; oral
2.5
25.6
223
1108
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
24.9
175
784
R41.3
ICD-10 Finland
Other amnesia
5.7
24.6
47
87
N05AD01
ATC
haloperidol; systemic
5.1
24.0
52
108
N30.0
ICD-10 Finland
Acute cystitis
2.6
22.2
148
643
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
21.8
171
803
N06AB04
ATC
citalopram; systemic
2.5
21.5
175
835
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.0
21.2
62
164
B01AC04
ATC
clopidogrel; oral
2.3
21.0
223
1192
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
216.1
20.7
21
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.6
20.7
72
215
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.8
20.7
121
491
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.0
20.7
104
389
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
20.3
84
280
F21, ,
ICPC
8.4
19.7
26
32
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.4
19.7
75
237
N06AX26
ATC
vortioxetine; oral
5.1
19.7
42
86
F06.7
ICD-10 Finland
Mild cognitive disorder
4.8
19.6
45
98
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
7.2
19.2
29
42
N02BE01
ATC
paracetamol; systemic, rectal
2.6
19.1
605
4875
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.8
18.4
42
91
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.8
18.4
29
44
SPAT1234
SPAT
Support of social functional capacity
3.3
18.1
73
239
N03AF02
ATC
oxcarbazepine; oral
5.5
17.5
34
64
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
17.4
169
862
I95.1
ICD-10 Finland
Orthostatic hypotension
3.3
16.6
66
214
R4120
NOMESCO Finland
Occupational therapy
3.3
16.4
64
205
S06.0
ICD-10 Finland
Concussion
2.8
16.4
92
363
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
16.2
204
1149
S01.0
ICD-10 Finland
Open wound of scalp
2.8
15.7
82
312
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
163.4
15.5
16
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.2
15.4
63
208
I63.8
ICD-10 Finland
Other cerebral infarction
7.2
15.3
23
33
F01
ICD-10 Finland
Vascular dementia
46.1
15.1
18
*
WYA20
NOMESCO Finland
Home visit
5.4
15.0
30
58
W19
ICD-10 Finland
Unspecified fall
2.6
15.0
98
418
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.5
14.6
53
162
SPAT1301
SPAT
No procedures
1.9
14.2
252
1588
S72.0
ICD-10 Finland
Fracture of neck of femur
2.9
14.1
70
259
SPAT1360
SPAT
Extensive global examination
3.0
14.1
67
242
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
14.0
290
1918
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
14.0
62
215
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
13.8
524
4179
A29
ICPC
General symptom/complaint other
2.3
13.6
117
564
F05.8
ICD-10 Finland
Other delirium
10.3
13.6
26
26
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.6
13.3
44
127
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
13.2
159
873
SPAT1254
SPAT
Administration of medicine
2.1
13.2
148
793
A06AD11
ATC
lactulose; oral
2.0
13.0
187
1095
A98
ICPC
Health maint/preventive medicine
2.0
13.0
560
4608
C09AA05
ATC
ramipril; oral
1.8
12.9
267
1755
N05BA06
ATC
lorazepam; systemic, sublingual
3.0
12.6
58
205
N06AB10
ATC
escitalopram; oral
2.4
12.6
93
419
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
12.5
12
*
E86
ICD-10 Finland
Volume depletion
3.7
12.4
40
113
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
5.9
12.3
22
38
SPAT1172
SPAT
Guidance concerning hydration
3.9
12.3
36
95
F01.2
ICD-10 Finland
Subcortical vascular dementia
38.3
12.2
15
*
R42
ICD-10 Finland
Dizziness and giddiness
1.9
12.1
204
1254
C10AA01
ATC
simvastatin; oral
1.7
11.7
405
3067
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
11.5
153
867
Y94.0
ICD-10 Finland
Accident at home
4.8
11.5
26
56
F01.0
ICD-10 Finland
Vascular dementia of acute onset
+∞
11.5
11
*
U04
ICPC
Incontinence urine
2.8
11.5
60
228
R55
ICD-10 Finland
Syncope and collapse
2.1
11.3
121
634
SPAT1252
SPAT
Overall medication plan or its review
2.4
11.2
78
341
WYA20, ,
SPAT
13.0
11.2
19
15
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.1
11.1
31
79
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
11.1
85
389
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
11.1
193
1195
C10AA05
ATC
atorvastatin; oral
1.7
11.1
329
2376
N03AX14
ATC
levetiracetam; systemic
4.6
11.0
26
58
P29
ICPC
Psychological sympt/compl other
4.6
11.0
26
58
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
10.8
149
853
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.2
10.8
44
145
AXX01, ,
SPAT
3.7
10.8
34
95
N18
ICPC
Paralysis/weakness
4.1
10.6
29
73
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.4
10.5
39
121
J01DB01
ATC
cefalexin; oral
1.8
10.5
509
4172
N02AA05
ATC
oxycodone; systemic
1.8
10.5
178
1091
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
10.4
10
*
S70.0
ICD-10 Finland
Contusion of hip
2.9
10.2
50
183
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.7
10.2
58
230
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
10.1
57
225
EBA00
NOMESCO Finland
Extraction of tooth
1.8
10.0
188
1185
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.5
10.0
35
105
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
9.9
187
1181
S00.0
ICD-10 Finland
Superficial injury of scalp
4.2
9.8
26
64
G04CA02
ATC
tamsulosin; oral
1.7
9.7
264
1844
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.5
9.7
33
97
N28
ICPC
Limited function/disability (N)
5.2
9.4
19
37
130
Kela drug reimbursment
Malignant tumour
0.2
9.2
13
599
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.7
9.1
21
46
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
9.1
102
542
WZC00, ,
SPAT
2.4
9.1
63
275
C07AB07
ATC
bisoprolol; oral
1.6
9.1
441
3545
B01AC07
ATC
dipyridamole; systemic
2.1
9.0
92
472
N17
ICPC
Vertigo/dizziness
2.0
9.0
107
581
A23
ICPC
Risk factor NOS
2.9
8.8
41
146
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
8.8
167
1053
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.6
8.8
28
79
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.8
8.6
44
165
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
8.6
116
657
N06AX21
ATC
duloxetine; oral
2.4
8.5
60
264
N05AD03
ATC
melperone; systemic
4.3
8.5
22
53
WX320
NOMESCO Finland
Spinalanesthesy
1.7
8.4
174
1121
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.6
8.4
49
197
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
4.7
8.4
19
41
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
8.3
103
567
SPAT1229
SPAT
Assessment of need for aid
2.1
8.3
78
388
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.4
8.2
20
46
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.4
8.2
54
231
H53.4
ICD-10 Finland
Visual field defects
3.8
8.1
24
64
ICB01, ,
SPAT
22.3
8.0
11
5
WX720
NOMESCO Finland
Own respiration
2.9
8.0
38
137
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
8.0
162
1038
WZB00, ,
SPAT
2.8
8.0
40
149
N30.9
ICD-10 Finland
Cystitis, unspecified
2.4
7.9
56
247
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.6
7.8
47
192
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.1
7.8
72
355
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.8
322
2457
G30
ICD-10 Finland
Alzheimer disease
45.5
7.7
9
*
WX704
NOMESCO Finland
Intubation
2.4
7.7
52
225
SPAT1167
SPAT
Insertion of urinary catheter
2.7
7.7
41
158
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
7.6
357
2799
XQ855, ,
SPAT
10.2
7.6
14
14
C03CA01
ATC
furosemide; systemic
1.6
7.5
387
3092
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.4
7.5
52
227
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.9
7.5
95
526
A01
ICPC
Pain general/multiple sites
2.1
7.4
70
348
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.3
7.4
55
248
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
7.4
109
635
L17
ICPC
Foot/toe symptom/complaint
1.7
7.3
179
1202
F0014, G301,
ICD-10 Finland
+∞
7.3
7
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
7.2
54
244
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.8
7.2
129
795
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
7.2
349
2743
WX212
NOMESCO Finland
Femoral plexus blockade
3.2
7.2
28
90
S20
ICPC
Corn/callosity
3.5
7.2
24
70
SPAT1262
SPAT
Handing over of treatment supplies
1.7
7.2
134
837
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.2
7.1
60
286
B01AF02
ATC
apixaban; oral
1.7
7.1
130
808
R4130
NOMESCO Finland
Speech therapy
3.4
7.0
25
76
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
7.0
149
965
N29
ICPC
Neurological sympt/complt other
5.9
6.9
18
31
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
6.9
167
1116
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
6.9
107
633
R1250, ,
SPAT
4.2
6.8
18
44
A78
ICPC
Infectious disease other/NOS
6.8
6.8
16
24
R5110, ,
SPAT
2.2
6.8
56
264
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.2
6.8
26
83
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
40.4
6.8
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.8
299
2296
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
6.7
42
175
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.6
6.7
37
145
G40.89
ICD-10 Finland
Other epilepsy
22.8
6.7
9
*
W06
ICD-10 Finland
Fall involving bed
6.0
6.6
17
29
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.2
6.6
25
79
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
6.6
74
393
-31
ICPC
Medical examin/health eval partial
2.1
6.6
62
309
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
6.5
38
153
F29
ICD-10 Finland
Unspecified nonorganic psychosis
6.9
6.5
15
22
R4110
NOMESCO Finland
Physiotherapy
1.6
6.5
186
1294
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.5
126
794
SPAT1263
SPAT
Sampling
1.5
6.5
262
1970
W10
ICD-10 Finland
Fall on and from stairs and steps
2.4
6.4
43
185
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
6.4
196
1387
B03BA03
ATC
hydroxocobalamin; parenteral
2.1
6.3
64
327
SPAT1081
SPAT
Cardiorespiratory global assessment
2.2
6.3
55
265
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.3
112
688
XF600, ,
SPAT
3.1
6.3
26
87
F01.1
ICD-10 Finland
Multi-infarct dementia
+∞
6.3
6
*
F0019, G301,
ICD-10 Finland
+∞
6.3
6
*
G04CB01
ATC
finasteride; oral
1.6
6.2
144
951
SPAT1014
SPAT
Treatment of eyes
3.6
6.2
20
57
P15
ICPC
Chronic alcohol abuse
5.8
6.2
16
28
R32
ICD-10 Finland
Unspecified urinary incontinence
2.9
6.2
28
99
K08.3
ICD-10 Finland
Retained dental root
2.2
6.1
51
243
WYA30, ,
SPAT
10.1
6.0
11
11
TAB00
NOMESCO Finland
Lumbar puncture
3.3
6.0
22
68
S52.5
ICD-10 Finland
Fracture of lower end of radius
2.0
6.0
67
355
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
432
2336
3.16
48.73
2.8
2.2
90.55
91.32
pmol/l
0.13
261
1193
293
1275
3.20
48.36
2.0
1.8
1060.63
1174.70
nmol/l
1.52
227
940
315
1437
3.14
47.80
1.9
1.6
17.69
19.87
nmol/l
1.72
289
1197
348
1747
2.94
43.45
2.9
2.1
—
—
—
0
0
358
1836
2.91
42.77
2.3
2.2
75.60
80.48
nmol/l
2.61
312
1561
251
1076
3.06
41.43
2.3
1.8
—
—
—
0
0
329
1641
2.87
40.99
2.5
2.1
208.54
253.20
u/l
0.39
316
1525
459
2745
2.89
40.00
6.9
6.6
1.22
1.21
mmol/l
1.84
400
2297
200
767
3.23
39.82
2.4
1.8
—
—
—
0
0
198
767
3.19
38.63
2.3
1.8
—
—
—
0
0
266
1225
2.87
37.96
6.1
4.5
96.26
225.65
ng/l
1.83
246
1113
423
2499
2.70
36.47
5.9
5.8
1.21
1.21
mmol/l
0.15
386
2253
504
3436
2.59
29.46
7.2
5.4
5053.67
2726.28
e6/l
—
6
69
391
2389
2.41
28.95
4.8
4.6
33.67
33.78
g/l
0.15
355
2200
459
3070
2.39
26.80
5.9
4.7
7.05
6.94
mmol/l
0.58
443
2894
157
685
2.66
23.46
4.7
3.2
297.35
321.67
ng/l
0.23
149
627
536
3969
2.41
22.84
5.0
4.7
1.91
2.11
mu/l
3.45
490
3455
115
441
2.92
21.90
1.5
1.6
—
—
—
0
0
513
3772
2.28
21.52
6.6
7.3
80.55
83.91
u/l
0.63
482
3497
279
1624
2.18
21.38
2.5
2.3
2.71
3.21
mg/l
3.06
240
1375
57
141
4.31
21.27
6.4
5.2
104.22
104.85
mmol/l
0.32
51
125
300
1803
2.15
21.11
2.6
3.4
2.34
2.35
mmol/l
0.21
260
1552
108
419
2.86
20.05
1.9
1.7
—
—
—
0
0
364
2394
2.06
19.76
3.4
3.0
49.95
58.87
u/l
1.25
332
2143
568
4431
2.39
19.59
27.4
19.6
28.86
29.25
mg/l
0.11
524
3756
398
2712
2.06
19.51
4.3
5.8
12.13
13.13
umol/l
0.49
367
2563
416
2935
2.00
17.87
20.2
22.5
1.58
1.47
inr
0.80
81
818
438
3165
2.00
17.35
3.5
3.8
15.25
15.21
pmol/l
0.11
391
2747
194
1094
2.06
15.26
2.9
3.3
2.46
2.47
mmol/l
0.43
172
939
41
103
4.16
14.97
1.2
2.1
24.30
36.48
umol/l
2.07
33
89
523
4127
2.00
14.82
6.3
6.9
42.06
41.82
mmol/mol
0.20
473
3682
452
3420
1.88
14.27
4.0
4.2
17.75
16.93
mm/h
0.40
408
3084
87
359
2.62
14.19
1.4
1.5
—
—
—
0
0
571
4678
2.11
14.18
34.0
24.0
139.30
139.30
mmol/l
0.01
560
4536
211
1255
1.97
14.14
1.6
1.8
410.44
5689054.80
pmol/l
0.50
178
1002
571
4681
2.10
14.11
34.3
24.3
4.00
4.03
mmol/l
2.24
559
4535
572
4703
2.09
13.85
38.5
28.9
229.36
232.61
e9/l
0.49
552
4536
572
4704
2.09
13.83
38.5
28.9
4.20
4.29
e12/l
3.73
549
4521
572
4704
2.09
13.83
38.6
29.1
126.02
129.41
g/l
5.95
562
4594
572
4704
2.09
13.83
38.6
29.0
37.23
38.26
%
2.02
443
4267
295
1972
1.85
13.73
3.0
2.9
139.10
162.43
ug/l
0.96
266
1755
160
883
2.05
13.14
2.2
2.6
19.48
21.18
%
0.72
101
756
68
259
2.80
12.94
6.1
4.1
1.85
1.63
%
1.57
62
240
165
930
2.01
12.74
2.2
2.6
2.20
2.23
g/l
0.33
149
852
555
4576
1.96
12.45
11.4
11.3
23.52
23.30
u/l
0.04
532
4351
466
3640
1.81
12.39
34.1
23.2
15.50
15.57
%
0.10
459
3558
311
2176
1.76
11.98
5.5
5.4
61.12
59.66
%
1.19
292
2010
90
409
2.37
11.91
6.7
5.7
25.15
24.15
mmol/l
1.12
81
387
316
2224
1.76
11.91
5.7
5.6
22.96
24.61
%
1.72
298
2049
56
201
2.94
11.87
1.3
1.2
—
—
—
0
0
171
1009
1.91
11.43
2.2
2.6
10.65
11.50
umol/l
1.00
158
930
164
956
1.93
11.36
3.7
3.4
1.16
2.13
e6/l
1.92
77
557
111
575
2.10
10.66
6.3
6.8
119.37
117.83
g/l
0.33
104
556
133
742
1.97
10.41
5.7
5.9
5.06
5.04
kpa
0.08
118
698
167
1005
1.86
10.40
3.6
3.1
1.18
1.31
e6/l
0.19
81
602
133
743
1.97
10.36
5.7
5.9
10.73
11.27
kpa
0.64
116
697
133
745
1.97
10.28
5.7
5.9
1.60
1.32
mmol/l
0.27
104
567
56
219
2.69
10.13
1.6
1.6
1.73
1.78
%
0.16
46
170
116
638
1.98
9.40
2.6
3.3
1.89
2.03
mmol/l
0.13
98
512
356
2701
1.64
9.38
6.5
8.0
4.72
4.45
e9/l
1.16
283
2302
17
17
10.21
9.06
1.0
1.1
45.00
34.03
ng/l
—
10
10
17
17
10.21
9.06
1.0
1.1
611.40
731.10
ng/l
—
10
10
115
639
1.95
9.04
2.6
3.4
5.79
5.80
kpa
0.04
109
611
510
4263
1.69
8.93
4.7
5.3
6.23
6.21
mmol/l
0.15
450
3705
228
1562
1.68
8.87
2.5
2.4
61.77
60.74
u/l
0.07
214
1434
309
2290
1.62
8.78
4.5
4.5
0.00
0.00
estimate
-0.00
46
497
148
906
1.80
8.58
2.3
2.8
0.79
0.82
mmol/l
1.93
136
838
303
2246
1.61
8.53
2.8
2.8
—
—
—
0
0
16
17
9.60
8.31
1.0
1.1
334.78
252.50
ng/l
—
9
10
20
46
4.44
8.19
1.3
1.3
—
—
—
0
0
20
46
4.44
8.19
1.3
1.3
—
—
—
0
0
303
2273
1.58
7.96
6.5
6.1
0.00
0.00
estimate
-0.00
38
443
304
2306
1.55
7.47
4.6
4.5
0.00
0.00
estimate
-0.00
39
440
500
4256
1.59
7.17
5.1
5.5
2.17
2.40
mmol/l
7.70
459
3743
129
806
1.73
6.87
3.9
4.9
1.01
1.06
mmol/l
0.80
119
745
130
821
1.71
6.65
2.7
2.3
1.76
1.80
%
0.17
108
723
76
407
1.97
6.61
2.6
2.9
125.14
123.12
g/l
0.34
76
394
481
4099
1.53
6.49
4.1
4.7
3.95
4.23
mmol/l
7.62
432
3638
274
2087
1.51
6.33
4.0
3.6
—
—
—
0
0
88
516
1.80
5.80
2.6
2.8
3.92
4.47
kpa
2.66
79
489
19
55
3.52
5.76
1.2
1.3
—
—
—
0
0
19
55
3.52
5.76
1.2
1.3
—
—
—
0
0
239
1803
1.49
5.65
4.3
3.7
84.82
97.79
e6/l
0.10
172
1439
279
2176
1.46
5.55
2.9
3.4
2225.49
2307.85
ng/l
0.12
238
1925
89
531
1.77
5.54
3.9
5.9
1.61
1.47
mmol/l
0.35
82
508
79
457
1.82
5.45
2.9
3.9
103.38
103.25
ng/l
0.00
65
390
259
1997
1.47
5.45
5.2
4.2
268.75
154.04
e6/l
0.26
175
1522
276
2156
1.46
5.42
4.7
6.0
10.87
6.67
ug/l
0.20
227
1894
469
4046
1.47
5.40
4.1
4.7
1.35
1.41
mmol/l
2.20
417
3544
68
379
1.88
5.27
1.7
2.0
421.87
382.36
nmol/l
0.81
62
334
78
466
1.76
4.84
1.7
2.4
30.88
32.59
u/l
0.29
64
403
80
491
1.71
4.52
1.4
2.0
0.21
0.19
g/l
1.37
71
450
38
184
2.13
4.39
2.1
2.6
4.14
4.14
pmol/l
0.00
32
162
212
1648
1.41
4.05
4.4
3.6
0.32
0.52
e6/l
1.35
152
1313
54
306
1.83
4.01
2.2
2.3
0.71
0.62
%
0.86
54
301
21
81
2.64
4.00
1.2
1.5
—
—
—
0
0
21
81
2.64
4.00
1.2
1.5
—
—
—
0
0
277
2256
1.37
3.99
5.0
4.5
44.10
49.92
ng/l
0.26
230
1821
446
3925
1.36
3.85
3.6
4.2
1.19
1.24
mmol/l
0.94
392
3401
138
1001
1.47
3.81
4.9
5.2
1.02
1.02
kg/l
0.43
18
174
42
224
1.93
3.77
3.6
3.3
0.75
0.89
nmol/l
1.04
32
176
21
84
2.55
3.74
1.2
1.4
—
—
—
0
0
48
271
1.83
3.63
2.1
1.8
4.05
2.53
ug/l
0.30
32
228
22
92
2.44
3.59
1.2
1.4
—
—
—
0
0
33
166
2.04
3.50
1.5
1.4
—
—
—
0
0
33
166
2.04
3.50
1.5
1.4
—
—
—
0
0
41
223
1.89
3.49
1.7
1.8
—
—
—
0
0
23
100
2.34
3.46
1.4
1.9
53.08
63.20
%
1.31
23
100
217
1734
1.36
3.42
4.3
5.0
22.89
22.32
%
0.19
101
959
44
248
1.83
3.36
1.7
1.9
—
—
—
0
0
89
605
1.54
3.36
2.0
2.7
6.27
5.82
ug/l
0.09
61
520
8
14
5.77
3.35
1.1
1.4
—
—
—
0
0
88
598
1.54
3.32
4.1
5.9
11.82
12.75
mmol/l
0.47
82
563
176
1372
1.38
3.22
2.9
2.8
30.61
37.50
u/l
1.93
160
1307
82
555
1.54
3.16
2.2
2.5
9.77
10.55
umol/l
0.07
65
480
26
127
2.09
3.00
1.2
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
45
270
1.71
2.82
2.5
2.4
0.34
0.34
u/ml
0.06
24
160
18
79
2.31
2.69
1.6
1.6
—
—
—
0
0
158
1248
1.34
2.63
2.2
2.6
—
—
—
0
0
24
121
2.02
2.58
1.2
1.6
—
—
—
0
0
25
132
1.93
2.38
1.4
1.4
286.18
270.42
ug/g
0.20
17
80
102
768
1.38
2.30
4.7
6.2
104.93
103.99
mmol/l
1.18
102
768
12
47
2.58
2.28
1.6
1.6
—
—
—
0
0
9
29
3.13
2.23
2.2
1.6
108.22
93.55
umol/l
—
9
29
9
29
3.13
2.23
2.3
2.3
—
—
—
0
0
40
254
1.61
2.08
2.2
2.1
9.90
10.69
g/l
0.47
33
220
6
15
4.02
2.04
1.0
1.1
—
—
—
0
0
40
256
1.60
2.02
2.1
2.1
2.78
3.07
g/l
0.85
34
223
16
77
2.10
1.98
1.1
1.5
—
—
—
0
0
5
11
4.57
1.94
1.2
1.1
—
—
—
0
0
5
11
4.57
1.94
1.2
1.0
—
—
—
0
0
5
11
4.57
1.94
1.2
1.1
—
—
—
0
0
51
349
1.50
1.94
2.2
1.7
1.43
1.52
g/l
0.31
44
301
167
1385
1.27
1.91
2.8
3.0
378.96
8678.10
umol/l
5.90
142
1141
36
229
1.60
1.88
2.4
2.3
1.80
1.32
g/l
0.20
28
192
6
17
3.55
1.84
2.2
1.2
0.81
0.72
nmol/l
—
6
12
41
271
1.54
1.83
2.1
2.0
3.43
3.55
g/l
0.27
35
239
134
1087
1.29
1.83
1.4
1.6
1.20
1.25
mmol/l
0.55
128
887
5
12
4.19
1.82
1.2
1.1
—
—
—
0
0
5
12
4.19
1.82
1.2
1.1
—
—
—
0
0
41
272
1.54
1.81
2.1
2.0
—
—
—
0
0
41
272
1.54
1.81
2.1
2.0
7.48
7.59
g/l
0.17
35
239
99
774
1.32
1.77
3.3
3.5
249.41
251.57
u/l
0.06
91
719
191
1625
1.24
1.75
2.7
3.1
6.59
6.63
mmol/l
0.05
165
1312
202
1731
1.23
1.73
5.4
5.0
—
—
—
0
0
5
13
3.86
1.71
2.2
1.4
44.60
56.09
ug/l
—
5
13
5
13
3.86
1.71
1.0
1.3
—
—
—
0
0
93
731
1.31
1.62
1.3
1.2
0.94
1.76
u/ml
0.86
12
165
191
1640
1.22
1.59
2.9
3.2
1265.50
350.57
mg/l
0.90
138
1097
8
33
2.44
1.54
1.4
1.1
1.85
1.56
nmol/l
—
8
26
7
27
2.61
1.51
1.1
1.1
—
—
—
0
0
30
194
1.57
1.51
1.9
2.0
0.02
0.00
g/l
0.46
24
172
29
186
1.58
1.51
1.9
2.1
0.00
0.00
g/l
-0.00
24
164
122
1006
1.26
1.47
1.6
1.6
1.57
1.52
mg/l
0.09
103
805
21
125
1.70
1.45
1.2
1.2
—
—
—
0
0
21
127
1.67
1.38
1.2
1.2
—
—
—
0
0
5
17
2.95
1.36
1.0
1.2
—
—
—
0
0
15
259
0.57
1.36
1.1
1.3
—
—
—
0
0
10
47
2.14
1.34
1.1
1.0
—
—
—
0
0
22
137
1.63
1.30
1.2
1.2
—
—
—
0
0
9
43
2.11
1.30
1.6
1.4
—
68.00
—
0
5
32
221
1.47
1.23
3.1
4.9
26.11
24.67
mmol/l
1.26
25
202
11
58
1.91
1.12
1.5
1.6
—
—
—
0
0
30
210
1.45
1.10
2.0
2.0
36.15
36.56
g/l
0.15
24
177
18
112
1.62
1.09
1.2
1.7
8310.83
16862.05
e6/l
0.92
12
80
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
16
97
1.66
1.07
1.3
2.5
207.94
219.51
%
0.19
16
92
194
1729
1.17
1.06
3.2
3.8
16.48
10.80
mg/mmol
0.78
134
1114
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
48
372
1.31
0.98
2.7
4.1
2.71
2.10
mmol/l
0.51
37
275
5
23
2.18
0.98
1.2
1.1
81.20
118.33
u/l
—
5
18
17
108
1.59
0.97
1.3
2.2
94.00
82.32
%
1.36
17
102
6
118
0.50
0.94
1.0
1.3
—
—
—
0
0
12
70
1.73
0.93
1.7
1.1
—
—
—
0
0
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
24
334
0.71
0.89
1.1
1.3
—
—
—
0
0
70
578
1.23
0.88
2.2
2.5
64.19
65.43
g/l
0.72
61
520
8
46
1.75
0.82
1.1
1.2
—
—
—
0
0
8
46
1.75
0.82
1.3
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
43
345
1.26
0.72
5.5
7.7
24.38
24.80
mmol/l
0.28
36
326
16
110
1.46
0.69
1.2
1.6
10.13
0.18
iu/ml
—
6
31
48
395
1.23
0.66
2.7
4.1
5.37
5.15
kpa
1.10
43
378
21
154
1.37
0.65
1.2
1.6
29.43
37.85
u/l
0.95
16
128
16
112
1.44
0.64
1.3
1.3
—
—
—
0
0
421
4042
1.10
0.62
26.3
19.3
64.87
66.11
ml/min/173m2
0.57
336
3393
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
13
185
0.70
0.59
1.5
1.6
—
—
—
0
0
8
53
1.52
0.58
1.1
1.3
—
—
—
0
0
13
90
1.45
0.55
1.2
1.1
—
23.34
—
0
5
70
610
1.16
0.55
4.6
4.0
—
—
—
0
0
6
38
1.58
0.54
1.0
1.3
391.67
235.86
pmol/l
—
6
33
30
241
1.26
0.53
3.3
2.8
—
—
—
0
0
6
96
0.62
0.52
1.2
1.6
—
—
—
0
0
7
45
1.56
0.49
1.1
1.1
76.00
57.24
u/l
—
7
38
15
111
1.36
0.47
1.3
1.5
—
—
—
0
0
11
77
1.44
0.45
2.4
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
—
—
0
0
5
34
1.47
0.40
1.2
1.2
—
2.11
—
0
9
0
18
0.00
0.40
0.0
2.3
—
136.67
—
0
18
0
19
0.00
0.39
0.0
1.2
—
19.42
—
0
12
142
1340
1.07
0.30
3.2
2.8
4.00
4.40
e6/l
0.28
129
1205
63
574
1.11
0.29
1.3
1.3
75.95
42.23
iu/ml
0.46
19
170
7
56
1.25
0.29
2.0
1.8
—
302.75
—
0
8
15
121
1.24
0.28
2.0
2.4
1.86
2.02
mg/l
0.24
15
102
17
141
1.21
0.26
1.2
1.4
—
—
—
0
0
9
76
1.19
0.24
3.8
3.9
—
—
—
0
0
66
611
1.09
0.24
4.2
4.9
36.33
33.52
%
1.34
40
386
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
2.61
—
0
7
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
10
80
1.25
0.20
1.1
1.2
—
—
—
0
0
18
156
1.16
0.18
1.4
1.3
—
—
—
0
0
130
1247
1.05
0.18
5.6
4.8
0.00
0.00
estimate
-0.00
34
417
5
66
0.76
0.17
1.0
1.5
3.52
1.81
mg/l
—
5
58
5
67
0.74
0.17
1.6
1.3
—
—
—
0
0
8
68
1.18
0.16
2.6
2.8
—
—
—
0
0
6
77
0.78
0.15
1.0
1.1
—
—
—
0
0
12
103
1.17
0.14
1.7
1.3
—
—
—
0
0
15
133
1.13
0.12
1.9
2.0
132.00
124.26
g/l
—
10
99
51
537
0.95
0.11
1.2
1.2
37.30
16.49
u/ml
—
9
175
26
242
1.08
0.09
1.6
2.8
22.45
12715.83
u/ml
0.63
20
208
5
46
1.09
0.09
1.2
1.6
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
7
66
1.06
0.08
2.9
3.6
23.29
34.55
u/ml
—
7
66
36
378
0.95
0.07
3.6
3.3
58.81
54.22
ml/min/173m2
0.40
16
185
6
71
0.84
0.07
1.0
1.3
9.00
14.11
u/l
—
6
61
8
78
1.03
0.07
1.1
1.4
—
—
—
0
0
9
85
1.06
0.07
1.1
1.1
—
—
—
0
0
16
173
0.92
0.06
2.0
1.5
—
—
—
0
0
12
132
0.91
0.06
1.7
2.3
15.80
15.24
%
—
5
67
62
636
0.97
0.05
11.1
9.9
—
—
—
0
0
10
110
0.91
0.05
1.3
1.2
1.13
1.15
g/l
—
10
104
21
202
1.04
0.02
2.0
2.6
—
5.64
—
0
10
124
1231
1.01
0.01
3.0
3.5
0.81
0.87
ug/l
0.41
91
901
67
664
1.01
0.00
2.5
3.8
4.66
29.36
ug/l
1.38
58
565
14
136
1.03
0.00
1.0
1.1
—
—
—
0
0
27
272
0.99
0.00
1.7
2.1
8.86
10.42
nmol/l
0.28
18
220
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
75
0.93
-0.00
1.4
1.5
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
-0.00
0.0
1.6
—
85.71
—
0
7
6
69
0.87
-0.00
1.5
1.3
—
—
—
0
0
6
68
0.88
-0.00
1.5
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
56.00
—
0
5
7
75
0.93
-0.00
1.3
1.1
1.23
0.89
nmol/l
—
7
63
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
8.23
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
73.60
—
0
5
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
84.83
—
0
6
0
7
0.00
-0.00
0.0
3.4
—
73.86
—
0
7
6
69
0.87
-0.00
1.0
1.1
—
—
—
0
0
6
69
0.87
-0.00
1.5
1.3
—
—
—
0
0
6
68
0.88
-0.00
1.5
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.5
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
91
0.99
-0.00
6.1
3.2
69.78
62.62
%
—
9
91
6
60
1.00
-0.00
1.2
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: VD_MX – Vascular dementia (mixed)
GWS hits: 2
This endpoint is excluded (different definition than used in FinnGen).