Vascular dementia (subcortical)

VD_SC

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F01.2
  • Cause of death: ICD-10 F01.2

2 out of 7 registries used, show all original rules.

1287

4. Check minimum number of events

None

1287

5. Include endpoints

None

1287

6. Filter based on genotype QC (FinnGen only)

1253

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F01
Name in latin
Dementia vascularis subcorticalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1253 539 714
Unadjusted period prevalence (%) 0.27 0.19 0.33
Median age at first event (years) 81.32 82.78 80.21

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1287
Matched controls
12870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06DA02
ATC
donepezil; oral
87.4
307.7
242
34
F01.2
ICD-10 Finland
Subcortical vascular dementia
1005.9
307.7
458
7
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
1138.5
307.7
663
12
N06DA03
ATC
rivastigmine; oral, transdermal
109.3
307.7
195
21
N06DX01
ATC
memantine; oral
129.9
307.7
427
49
F03
ICD-10 Finland
Unspecified dementia
42.6
307.7
249
72
F01.9
ICD-10 Finland
Vascular dementia, unspecified
136.8
307.7
207
18
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
11.4
307.7
481
641
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
2285.3
307.7
331
*
N05AX08
ATC
risperidone; systemic
13.8
307.7
368
362
G30.1
ICD-10 Finland
Alzheimer disease with late onset
134.8
307.7
316
31
P20
ICPC
Memory disturbance
7.8
290.5
579
1217
P70
ICPC
Dementia
21.7
177.3
135
69
N05AH04
ATC
quetiapine; oral
6.4
165.0
328
653
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
67.4
160.3
88
14
N06DA04
ATC
galantamine; oral
234.9
144.2
146
7
A28
ICPC
Limited function/disability NOS
4.2
137.9
614
2315
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
41.6
135.2
82
21
R41.3
ICD-10 Finland
Other amnesia
10.0
125.9
151
168
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
114.3
108
*
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
206.2
110.4
113
6
F01.24
ICD-10 Finland
Subcortical vascular dementia other additional symptoms of mixed type
574.5
108.5
106
*
R53
ICD-10 Finland
Malaise and fatigue
3.5
102.3
532
2141
SPAT1053
SPAT
Memory test
3.6
96.9
438
1603
G30.8
ICD-10 Finland
Other Alzheimer disease
107.4
83.1
90
9
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
10.9
81.7
90
88
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.0
79.8
663
3392
R41.0
ICD-10 Finland
Disorientation, unspecified
6.3
75.4
134
232
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.4
62.6
274
955
N05AH03
ATC
olanzapine; systemic
7.0
59.3
94
144
F01.23
ICD-10 Finland
Subcortical vascular dementia other additional symptoms, mainly depression
293.9
55.7
56
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
89.9
54.4
60
7
F05.9
ICD-10 Finland
Delirium, unspecified
6.3
53.5
94
160
N06AX26
ATC
vortioxetine; oral
6.2
51.9
92
158
AA1AD
NOMESCO Finland
CT of head and brain
2.4
51.0
542
2959
F06.7
ICD-10 Finland
Mild cognitive disorder
5.5
50.9
102
197
F01.21
ICD-10 Finland
Subcortical vascular dementia without additional symptoms, mainly paranoidism
517.6
50.8
50
*
N06AX11
ATC
mirtazapine; oral
2.4
48.6
489
2592
N03AG01
ATC
valproic acid; systemic, rectal
5.4
47.6
97
190
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
46.7
456
2377
F01.22
ICD-10 Finland
Subcortical vascular dementia with additional symptoms, mainly hallucinations
232.9
44.2
45
*
L28
ICPC
Limited function/disability (L)
2.4
42.9
402
2045
N05BA04
ATC
oxazepam; oral
2.4
42.6
408
2093
XA800
NOMESCO Finland
Neuropsychological investigation
7.7
41.4
59
80
S01.0
ICD-10 Finland
Open wound of scalp
3.2
39.8
175
602
N06AB10
ATC
escitalopram; oral
2.9
38.7
211
820
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.4
36.5
305
1460
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
36.0
235
1000
A04
ICPC
Weakness/tiredness general
2.5
35.9
287
1346
SPAT1216
SPAT
Assessment of functional ability
2.3
35.5
342
1739
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
35.5
344
1754
TAB00
NOMESCO Finland
Lumbar puncture
5.7
34.5
65
118
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.8
33.9
189
741
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
32.7
314
1589
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
32.4
31
*
N02BE01
ATC
paracetamol; systemic, rectal
2.7
32.3
1116
9143
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
31.3
546
3458
N02AA05
ATC
oxycodone; systemic
2.2
31.0
367
2014
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.7
30.0
186
768
F01
ICD-10 Finland
Vascular dementia
38.0
29.4
37
10
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.2
28.6
122
410
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.2
28.6
121
405
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
7.1
28.5
43
62
S06.0
ICD-10 Finland
Concussion
2.7
28.5
174
712
I95.1
ICD-10 Finland
Orthostatic hypotension
3.2
27.8
118
395
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.1
27.1
124
434
R42
ICD-10 Finland
Dizziness and giddiness
2.0
26.9
404
2400
F21, ,
ICPC
6.4
26.3
44
71
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
26.1
181
786
WYA20
NOMESCO Finland
Home visit
5.2
25.8
54
108
G30
ICD-10 Finland
Alzheimer disease
95.4
25.7
28
*
N30.0
ICD-10 Finland
Acute cystitis
2.2
25.6
259
1325
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
25.1
196
898
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
24.6
965
7740
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
35.2
24.3
31
9
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
24.2
274
1462
N06AB04
ATC
citalopram; systemic
2.1
23.8
281
1522
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
23.8
112
398
R55
ICD-10 Finland
Syncope and collapse
2.2
23.3
229
1155
F01.0
ICD-10 Finland
Vascular dementia of acute onset
+∞
23.0
22
*
J01DB01
ATC
cefalexin; oral
1.9
22.8
954
7699
SPAT1254
SPAT
Administration of medicine
2.0
22.5
279
1536
R4110
NOMESCO Finland
Physiotherapy
1.9
22.3
383
2357
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
21.9
21
*
S72.0
ICD-10 Finland
Fracture of neck of femur
2.7
21.4
124
492
W19
ICD-10 Finland
Unspecified fall
2.3
21.3
171
791
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.1
21.1
58
145
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.4
21.1
165
755
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
20.9
259
1421
F29
ICD-10 Finland
Unspecified nonorganic psychosis
6.6
20.5
33
51
A06AD11
ATC
lactulose; oral
1.9
20.0
334
2024
N06AB06
ATC
sertraline; oral
2.8
19.4
100
373
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
18.9
216
1148
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.0
18.9
84
289
Z02.7
ICD-10 Finland
Issue of medical certificate
2.6
18.8
117
481
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
3.1
18.7
80
269
G30.0
ICD-10 Finland
Alzheimer disease with early onset
192.7
18.6
19
*
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
192.7
18.6
19
*
U04
ICPC
Incontinence urine
2.5
17.9
115
480
Z75.5
ICD-10 Finland
Holiday relief care
5.6
17.5
33
60
R5110, ,
SPAT
2.4
17.0
122
536
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.4
16.9
42
97
N30.9
ICD-10 Finland
Cystitis, unspecified
2.5
16.8
113
481
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
172.1
16.5
17
*
A29
ICPC
General symptom/complaint other
2.0
16.3
204
1116
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
16.3
110
469
Z2445
NOMESCO Finland
Psychologist
5.4
15.7
31
59
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
+∞
15.7
15
*
A98
ICPC
Health maint/preventive medicine
1.8
15.6
1010
8658
C10AA01
ATC
simvastatin; oral
1.6
15.1
718
5668
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
14.8
84
329
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
4.1
14.3
39
97
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
14.2
268
1667
F22.0
ICD-10 Finland
Delusional disorder
5.7
14.2
26
46
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
43.0
14.1
17
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.5
14.1
34
77
Z2221
NOMESCO Finland
Medical doctor
1.7
14.0
348
2332
Z3226
NOMESCO Finland
Physiotherapist
1.8
13.8
257
1590
N05BA06
ATC
lorazepam; systemic, sublingual
2.5
13.8
92
390
R44.3
ICD-10 Finland
Hallucinations, unspecified
11.6
13.8
25
22
Y94.0
ICD-10 Finland
Accident at home
3.7
13.8
44
123
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.6
13.7
78
307
F0019, G301,
ICD-10 Finland
+∞
13.6
13
*
130
Kela drug reimbursment
Malignant tumour
0.2
13.4
26
1004
G04BD12
ATC
mirabegron; oral
1.9
13.3
187
1062
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.1
13.1
56
188
A01
ICPC
Pain general/multiple sites
2.1
13.1
133
673
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
13.0
140
724
N05AD01
ATC
haloperidol; systemic
2.9
13.0
60
211
ZXA05
NOMESCO Finland
Left side
1.6
13.0
382
2665
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
12.9
102
467
S01
ICD-10 Finland
Open wound of head
4.9
12.9
28
58
E86
ICD-10 Finland
Volume depletion
2.9
12.8
59
207
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.6
12.8
76
305
P99
ICPC
Psychological disorders other
5.4
12.8
25
47
SPAT1301
SPAT
No procedures
1.6
12.6
419
3004
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.5
12.5
83
352
EBA00
NOMESCO Finland
Extraction of tooth
1.6
12.5
331
2248
WX212
NOMESCO Finland
Femoral plexus blockade
3.0
12.3
53
179
ZXD35
NOMESCO Finland
Usual procedure
2.8
12.3
60
218
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
13.5
12.0
20
15
SPAT1360
SPAT
Extensive global examination
2.2
11.9
99
463
S70.0
ICD-10 Finland
Contusion of hip
2.5
11.8
77
323
Z3231
NOMESCO Finland
Registered nurse
1.6
11.8
369
2601
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
11.8
183
1070
ZXA00
NOMESCO Finland
Right side
1.6
11.7
394
2823
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
11.6
50
169
F009, G309,
ICD-10 Finland
+∞
11.5
11
*
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
11.5
11
*
F01.8
ICD-10 Finland
Other vascular dementia
121.1
11.4
12
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
11.4
297
2001
N17
ICPC
Vertigo/dizziness
1.8
11.3
190
1136
N06AX21
ATC
duloxetine; oral
2.1
11.3
110
547
N05AX12
ATC
aripiprazole; systemic
9.7
11.3
22
23
A10AB05
ATC
insulin aspart; parenteral
2.1
11.2
111
556
A10AE04
ATC
insulin glargine; parenteral
1.9
11.2
142
777
AXX01, ,
SPAT
2.9
11.1
51
179
R32
ICD-10 Finland
Unspecified urinary incontinence
2.8
11.1
54
196
SPAT1229
SPAT
Assessment of need for aid
1.9
11.0
144
796
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.2
10.9
29
71
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
10.9
601
4769
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
10.8
252
1651
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
10.7
102
503
C08CA01
ATC
amlodipine; oral
1.5
10.6
590
4678
C07AB07
ATC
bisoprolol; oral
1.5
10.6
773
6468
P29
ICPC
Psychological sympt/compl other
3.4
10.6
38
115
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
10.5
301
2073
F01.1
ICD-10 Finland
Multi-infarct dementia
+∞
10.4
10
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.9
10.4
48
169
F00
ICD-10 Finland
Dementia in Alzheimer disease
32.8
10.3
13
*
XCK10
NOMESCO Finland
Photography of fundus of eye
1.8
10.3
163
958
WX110, ,
SPAT
2.8
10.2
52
193
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.2
646
5241
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.0
10.2
45
155
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
14.7
10.0
16
11
U13
ICPC
Bladder symptom/complaint other
2.8
10.0
51
190
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
10.0
186
1146
R33
ICD-10 Finland
Retention of urine
1.8
9.9
164
975
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
9.9
198
1244
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.7
525
4120
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.3
9.7
19
36
R1250
NOMESCO Finland
Evaluation of functional capability
4.0
9.6
27
69
K08.3
ICD-10 Finland
Retained dental root
2.1
9.6
96
484
F01.39
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without information on additional symptoms
100.8
9.4
10
*
F01.34
ICD-10 Finland
Mixed cortical and subcortical vascular dementia are other mixed symptoms of mixed type
100.8
9.4
10
*
Z2446
NOMESCO Finland
Social worker
2.1
9.2
86
421
C10AA05
ATC
atorvastatin; oral
1.4
9.2
557
4453
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.1
392
2932
Z01.9
ICD-10 Finland
Special examination, unspecified
2.3
9.1
71
324
R44.1
ICD-10 Finland
Visual hallucinations
8.4
9.1
19
23
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.5
9.1
58
242
G20
ICD-10 Finland
Parkinson disease
2.5
9.1
54
218
N28
ICPC
Limited function/disability (N)
3.7
9.0
28
77
J01CA08
ATC
pivmecillinam; oral
1.5
9.0
447
3438
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
6.9
8.9
21
31
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.4
8.8
31
93
E000001, ,
ATC
1.6
8.8
220
1461
A10BH05
ATC
linagliptin; oral
2.0
8.7
96
501
EBA00, ,
SPAT
3.2
8.7
34
109
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.6
339
2486
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.6
8.6
20
44
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.3
8.4
60
263
SPAT1304
SPAT
Counselling and guidance related to ageing
1.7
8.4
154
943
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
7.9
8.4
18
23
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.3
8.4
62
277
G04CA02
ATC
tamsulosin; oral
1.5
8.4
399
3038
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.1
8.3
33
107
C03CA01
ATC
furosemide; systemic
1.4
8.3
672
5623
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.2
575
4686
S22.3
ICD-10 Finland
Fracture of rib
2.0
8.2
92
483
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
8.1
282
2012
N30
ICD-10 Finland
Cystitis
2.0
8.1
90
471
SPAT1101
SPAT
Orthostatic test
2.0
8.1
89
464
W06
ICD-10 Finland
Fall involving bed
4.1
8.1
22
55
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
3.7
8.0
25
69
AXX01
NOMESCO Finland
Memory assessment
22.2
8.0
11
5
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.1
8.0
*
306
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
8.0
179
1155
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
8.0
187
1220
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
8.0
50
207
G72.8
ICD-10 Finland
Other specified myopathies
2.9
7.9
36
126
M79.6
ICD-10 Finland
Pain in limb
1.4
7.9
414
3200
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.6
7.9
45
178
C09AA05
ATC
ramipril; oral
1.4
7.9
419
3249
J01CA04
ATC
amoxicillin; systemic
1.4
7.8
844
7383
I95.9
ICD-10 Finland
Hypotension, unspecified
3.0
7.7
34
117
F01.80
ICD-10 Finland
Other specified vascular dementia without additional symptoms
45.3
7.7
9
*
I95.2
ICD-10 Finland
Hypotension due to drugs
4.5
7.7
18
40
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.7
308
2263
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
7.7
120
1949
E0000UV, ,
ATC
1.4
7.6
426
3327
SPAT1336
SPAT
Request for examination
2.2
7.6
61
282
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
7.6
250
1764
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
3.5
7.6
25
72
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.5
7.6
25
72
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.9
7.6
99
548
A10BA02
ATC
metformin; oral
1.4
7.5
405
3140
KMAK, ,
NOMESCO Finland
1.4
7.5
400
3095
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
7.5
431
3382
S01.8
ICD-10 Finland
Open wound of other parts of head
3.6
7.4
24
68
Z51.5
ICD-10 Finland
Palliative care
1.7
7.4
148
928
SPAT1234
SPAT
Support of social functional capacity
1.9
7.4
89
480
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.6
7.3
42
167
F01.89
ICD-10 Finland
Other specified vascular dementia without information on additional symptoms
+∞
7.3
7
*
F0014, G301,
ICD-10 Finland
+∞
7.3
7
*
SPAT1255
SPAT
Intravenous administration of medicine
1.9
7.3
97
540
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
2.6
7.3
39
150
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.4
7.2
48
205
N06AX16
ATC
venlafaxine; oral
1.9
7.2
89
484
N87
ICPC
Parkinsonism
3.6
7.2
23
65
L17
ICPC
Foot/toe symptom/complaint
1.5
7.2
304
2254
D21
ICPC
Swallowing problem
3.2
7.1
27
85
ZXE00
NOMESCO Finland
One hour or less
1.4
7.1
442
3510
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.7
7.1
120
719
K02.1
ICD-10 Finland
Caries of dentine
1.4
7.0
434
3440
R50.9
ICD-10 Finland
Fever, unspecified
1.6
7.0
176
1168
N05AB03
ATC
perphenazine; systemic, rectal
2.8
6.8
33
120
D09
ICPC
Nausea
2.4
6.8
44
185
D07AA02
ATC
hydrocortisone; topical
1.6
6.8
144
915
Z71.8
ICD-10 Finland
Other specified counselling
1.5
6.8
276
2026
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.5
6.8
41
167
R11
ICD-10 Finland
Nausea and vomiting
1.7
6.8
117
704
B01AC04
ATC
clopidogrel; oral
1.4
6.8
290
2152
SPAT1139
SPAT
Nutrition survey
2.3
6.7
49
218
U05
ICPC
Urination problems other
1.9
6.7
81
437
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
22.6
6.7
9
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.9
6.6
82
446
A02BC02
ATC
pantoprazole; systemic
1.4
6.6
781
6836
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
2.8
6.6
31
111
A10AE05
ATC
insulin detemir; parenteral
2.0
6.6
70
361
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
6.6
292
2178
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.6
121
742
A23
ICPC
Risk factor NOS
2.1
6.5
63
314
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
6.5
160
1055
N03AX09
ATC
lamotrigine; oral
3.1
6.5
26
85
ZXD20
NOMESCO Finland
Day surgery
1.6
6.5
142
911
S20.2
ICD-10 Finland
Contusion of thorax
2.1
6.5
59
288
ZXD05
NOMESCO Finland
Urgent procedure
1.4
6.5
371
2897
N06AX12
ATC
bupropion; oral
3.0
6.4
27
91
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.8
6.4
96
555
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
14.4
6.4
10
7
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.3
6.4
47
210
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
2.2
6.4
50
230
G04CB01
ATC
finasteride; oral
1.5
6.3
215
1523
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
11.1
6.3
11
10
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.0
6.3
27
92
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.3
478
3903
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
6.2
5
279
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.2
534
4437
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.2
217
1544
R06AE07
ATC
cetirizine; oral
1.4
6.2
377
2967
K59.09
ICD-10 Finland
Constipation, unspecified
1.7
6.2
101
598
K28
ICPC
Limited function/disability (K)
2.3
6.2
45
200
H3600, E113,
ICD-10 Finland
2.9
6.2
27
93
T89
ICPC
Diabetes insulin dependent
2.6
6.2
33
127
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.8
6.1
86
487
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.2
6.1
47
214
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.7
6.1
113
694
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.0
6.1
60
302
T90
ICPC
Diabetes non-insulin dependent
1.4
6.1
296
2244
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
3.1
6.1
24
78
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.5
6.0
20
58
A27
ICPC
Fear of other disease NOS
2.0
6.0
63
324
N06AG02
ATC
moclobemide; oral
2.3
6.0
45
203

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
789
4443
3.00
79.35
2.7
2.2
90.90
92.55
pmol/l
0.45
478
2252
558
2650
2.95
76.22
1.9
1.6
17.87
19.74
nmol/l
2.05
528
2219
514
2442
2.84
68.65
1.9
1.8
1077.51
1215.36
nmol/l
2.83
397
1791
52
30
18.02
63.85
1.1
1.0
645.86
843.94
ng/l
1.11
37
17
446
2053
2.79
62.18
3.1
3.2
2.47
2.47
mmol/l
0.05
382
1747
51
30
17.66
62.03
1.1
1.0
348.63
245.24
ng/l
1.34
40
17
638
3543
2.59
60.41
2.2
2.2
77.04
81.11
nmol/l
3.05
581
3007
727
4491
2.42
51.98
4.2
4.6
34.04
33.69
g/l
0.92
664
4102
583
3345
2.36
48.31
4.4
4.3
—
—
—
0
0
790
5187
2.35
47.36
6.4
6.7
1.22
1.21
mmol/l
1.73
690
4332
631
3775
2.32
47.04
4.6
3.7
—
—
—
0
0
586
3399
2.33
46.99
2.7
3.4
2.36
2.35
mmol/l
0.64
522
2857
548
3136
2.30
44.82
3.2
3.9
7.41
7.40
ph
0.75
78
628
911
6500
2.37
42.95
7.7
5.6
5289.13
2526.47
e6/l
0.37
30
120
719
4715
2.19
40.78
5.4
6.0
1.21
1.21
mmol/l
1.08
677
4225
51
60
8.81
40.19
3.3
3.1
314.50
323.73
umol/l
0.16
44
51
532
3135
2.19
39.18
2.4
2.1
303.70
208.98
u/l
1.20
503
2904
885
6360
2.25
39.11
33.8
27.0
329.09
329.83
g/l
1.42
860
6260
812
5808
2.08
33.97
5.5
4.8
7.21
6.98
mmol/l
1.40
772
5487
581
3704
2.04
33.25
5.5
4.1
254.79
131.30
e6/l
0.58
408
2789
406
2278
2.14
32.69
5.2
4.6
160.87
257.17
ng/l
0.83
377
2070
969
7464
2.21
32.58
5.4
4.8
2.05
2.12
mu/l
0.63
902
6551
532
3315
2.03
32.17
4.4
3.6
109.50
92.46
e6/l
0.21
402
2631
1046
8364
2.34
31.25
25.9
19.7
29.45
29.03
mg/l
0.16
943
7056
862
6424
2.04
30.63
6.6
5.0
—
—
—
0
0
325
1751
2.15
28.49
4.0
3.2
2.09
2.19
e6/l
0.08
168
1015
808
6012
1.92
27.28
3.8
3.8
15.31
15.31
pmol/l
0.00
750
5259
531
3502
1.88
25.59
5.2
4.1
5.89
6.00
ph
—
9
93
479
3084
1.88
24.67
2.4
2.3
2.97
3.29
mg/l
1.24
413
2613
901
7067
1.92
24.52
6.3
7.4
80.76
84.01
u/l
0.88
847
6556
1058
8796
2.14
24.05
31.6
24.3
139.29
139.26
mmol/l
0.13
1028
8534
326
1861
2.01
23.92
3.9
3.0
1.13
1.51
e6/l
0.82
165
1118
1058
8803
2.13
23.89
31.8
24.5
4.00
4.03
mmol/l
3.46
1027
8529
619
4395
1.79
22.57
5.8
4.4
0.00
0.01
estimate
0.96
85
949
1058
8861
2.09
22.57
35.9
29.2
37.50
38.14
%
2.02
927
8067
1058
8862
2.09
22.55
35.5
29.1
235.60
233.98
e9/l
0.33
1015
8552
467
3049
1.83
22.54
4.2
3.5
0.75
0.57
e6/l
0.61
350
2414
1058
8863
2.09
22.53
35.5
29.1
4.20
4.28
e12/l
5.43
1010
8512
1058
8863
2.09
22.53
35.8
29.3
126.52
129.11
g/l
6.45
1030
8654
1058
8863
2.09
22.53
35.4
29.0
30.42
30.39
pg
0.22
1026
8642
1058
8863
2.09
22.53
35.4
29.0
92.24
91.99
fl
0.93
1025
8643
1058
8866
2.09
22.46
35.5
29.1
7.46
7.13
e9/l
1.95
1014
8509
621
4423
1.78
22.32
5.9
4.5
0.00
0.00
estimate
-0.00
73
845
448
2897
1.84
22.25
4.1
3.5
—
—
—
0
0
51
112
4.70
21.86
1.5
1.4
226.03
260.69
e6/l
0.06
40
91
734
5529
1.76
21.36
23.5
23.1
1.54
1.48
inr
0.56
170
1528
54
127
4.39
21.27
1.3
1.3
622.08
593.70
mg/l
0.16
49
122
861
6802
1.80
21.16
31.3
23.5
15.30
15.66
%
1.17
836
6645
50
112
4.60
20.92
1.4
1.3
3.00
42.47
e6/l
0.78
38
88
607
4366
1.74
20.50
8.3
6.0
0.00
0.00
estimate
-0.00
72
838
46
102
4.64
19.49
1.2
1.3
—
—
—
0
0
813
6453
1.71
18.21
4.1
4.3
16.79
16.97
mm/h
0.10
754
5838
1018
8626
1.86
17.99
11.0
11.5
21.28
23.17
u/l
2.42
977
8187
617
4571
1.67
17.82
3.2
3.1
53.08
59.77
u/l
0.95
565
4084
996
8395
1.82
17.75
23.1
19.4
—
—
—
0
0
368
2374
1.77
17.66
3.4
3.2
556.25
532.35
mosm/kgh2o
1.40
299
2029
335
2131
1.77
16.74
4.7
4.3
—
—
—
0
0
664
5084
1.63
16.32
4.1
5.9
12.95
13.20
umol/l
0.14
630
4799
666
5114
1.63
16.09
5.7
8.1
4.90
4.43
e9/l
3.86
540
4427
213
1196
1.94
15.78
3.4
3.4
1.59
2.08
mmol/l
0.98
178
961
185
999
1.99
15.32
3.0
2.9
4.27
4.44
kpa
0.56
176
955
212
1204
1.91
15.14
3.4
3.4
5.78
5.81
kpa
0.14
203
1157
580
4385
1.59
14.38
4.5
5.1
0.04
0.04
e9/l
0.37
466
3712
578
4373
1.58
14.25
4.5
5.1
0.67
0.64
e9/l
1.24
463
3687
562
4231
1.58
14.11
4.9
5.7
23.72
24.27
%
0.48
520
3909
591
4506
1.58
14.01
4.7
5.3
0.21
0.20
e9/l
0.67
478
3861
211
1232
1.85
13.75
3.4
3.3
—
7.39
—
0
8
357
2420
1.66
13.73
3.0
2.8
5.47
5.03
e6/l
0.32
316
2170
119
568
2.21
13.61
2.9
3.3
23.97
24.07
mmol/l
0.11
114
547
585
4471
1.57
13.59
4.6
5.3
1.87
1.78
e9/l
0.37
466
3873
549
4145
1.57
13.40
4.9
5.5
60.67
60.15
%
0.42
509
3841
297
1935
1.70
13.22
6.4
5.0
1.01
1.02
kg/l
1.14
41
324
549
4163
1.56
13.04
5.2
5.8
8.85
9.04
%
0.69
510
3843
501
3731
1.56
12.84
3.0
3.0
119.92
157.24
ug/l
4.71
461
3335
215
1288
1.80
12.83
3.8
3.3
321.01
316.85
ng/l
0.04
205
1176
545
4143
1.55
12.70
4.8
5.5
2.74
2.78
%
0.16
504
3817
533
4036
1.55
12.62
4.5
5.4
0.59
0.60
%
0.29
495
3725
341
2332
1.63
12.49
1.9
1.8
430.87
10512570.04
pmol/l
1.06
295
1855
762
6245
1.54
12.48
4.7
4.8
—
—
—
0
0
269
1740
1.69
12.20
1.6
1.9
30.04
30.46
s
0.43
263
1681
353
2454
1.60
12.02
3.8
4.0
75.89
79.66
%
1.99
344
2382
354
2505
1.57
11.03
2.7
2.8
32.66
35.68
u/l
0.65
325
2356
167
971
1.83
10.92
6.4
7.0
—
—
—
0
0
920
8018
1.52
10.04
5.0
5.3
6.30
6.18
mmol/l
1.45
843
6998
150
868
1.82
9.94
2.7
2.4
30.46
36.21
u/l
0.90
126
731
84
396
2.20
9.92
1.8
2.2
1051.00
587.55
ug/l
0.35
76
372
542
4279
1.46
9.72
4.9
4.7
41.20
58.21
ng/l
1.83
414
3486
897
7802
1.49
9.66
7.2
6.9
43.15
41.77
mmol/mol
2.71
836
6993
172
1045
1.75
9.66
2.0
2.6
11.55
11.43
umol/l
0.02
140
895
58
236
2.53
9.55
1.5
2.3
—
—
—
0
0
108
571
1.97
9.42
2.3
2.4
0.61
0.63
%
0.47
108
566
21
46
4.62
9.08
1.5
1.3
—
—
—
0
0
209
1369
1.63
8.82
5.8
6.1
1.61
1.37
mmol/l
0.38
174
1050
56
233
2.47
8.82
1.2
1.2
—
—
—
0
0
147
881
1.75
8.64
3.0
3.6
89.05
106.42
ng/l
1.82
119
730
268
1885
1.53
8.29
2.1
2.5
10.31
11.33
umol/l
1.73
245
1743
253
1758
1.55
8.27
2.1
2.5
2.21
2.25
g/l
0.46
235
1612
21
50
4.25
8.21
3.1
1.6
1.60
3.07
u/field
0.59
15
30
240
1665
1.54
7.87
1.9
2.8
0.81
0.81
mmol/l
0.08
210
1525
305
2228
1.48
7.82
4.7
6.4
—
—
—
0
0
507
4069
1.41
7.81
4.9
5.8
—
—
—
0
0
203
1364
1.58
7.66
5.9
6.1
5.00
5.07
kpa
0.42
195
1279
203
1365
1.58
7.63
5.8
6.1
10.75
11.46
kpa
1.23
195
1280
391
3012
1.43
7.55
2.4
2.4
55.88
60.39
u/l
0.78
363
2749
901
8009
1.42
7.37
5.1
5.5
2.26
2.41
mmol/l
6.05
839
7048
105
602
1.81
7.17
8.2
8.5
—
—
—
0
0
45
188
2.44
7.08
1.7
2.0
27.36
34.56
umol/l
1.08
36
162
11
8
13.85
6.89
5.9
1.6
0.36
1.13
u/field
—
11
8
181
1216
1.57
6.81
6.4
6.5
94.25
95.16
%
0.57
175
1161
220
1555
1.50
6.54
2.1
2.3
1.72
1.80
%
0.57
188
1368
234
1675
1.49
6.54
2.2
2.6
19.26
20.55
%
0.85
178
1427
174
1184
1.54
6.17
1.8
1.8
—
—
—
0
0
255
1880
1.44
6.10
1.7
1.6
1.46
1.56
mg/l
0.23
217
1473
394
3143
1.37
5.93
2.3
2.7
—
—
—
0
0
497
4141
1.33
5.51
3.1
3.4
2183.97
2366.62
ng/l
0.39
434
3659
38
168
2.30
5.34
1.6
2.0
57.63
58.87
%
0.12
38
168
128
840
1.58
5.32
3.2
3.9
—
—
—
0
0
42
828
0.49
5.07
1.3
1.4
—
—
—
0
0
113
734
1.59
4.92
1.8
2.0
390.25
385.91
nmol/l
0.08
105
647
18
56
3.25
4.90
1.4
1.1
—
—
—
0
0
439
3647
1.31
4.82
4.6
5.9
2.42
6.04
ug/l
2.28
397
3185
138
958
1.49
4.46
1.5
2.0
0.19
0.19
g/l
0.37
126
874
21
78
2.72
4.26
1.7
1.4
9.86
10.18
%
0.11
21
78
32
147
2.21
4.17
1.1
1.1
—
—
—
0
0
10
18
5.59
3.97
1.4
1.2
—
—
—
0
0
60
351
1.74
3.94
4.1
3.8
—
—
—
0
0
46
248
1.89
3.93
1.2
1.3
65.38
59.28
mmol/l
0.60
37
194
841
7717
1.26
3.73
4.2
4.7
4.10
4.26
mmol/l
4.74
767
6844
281
2268
1.31
3.69
6.8
4.3
—
—
—
0
0
39
204
1.94
3.66
3.2
2.6
—
—
—
0
0
11
26
4.26
3.51
2.5
3.0
25.33
27.75
umol/l
—
6
20
828
7614
1.25
3.46
4.0
4.7
1.40
1.43
mmol/l
1.23
753
6668
442
3801
1.25
3.43
8.8
10.8
0.00
0.00
e9/l
1.95
312
3099
26
121
2.17
3.33
2.4
2.2
2.40
2.54
u/field
0.04
15
26
491
4285
1.24
3.30
2.5
2.8
—
—
—
0
0
13
43
3.04
3.25
1.1
1.0
124.43
131.07
nmol/l
0.20
13
43
193
1505
1.33
3.22
4.2
4.8
1.04
1.04
mmol/l
0.00
171
1380
90
619
1.49
3.10
8.3
8.1
24.57
24.57
mmol/l
0.00
84
582
190
1491
1.32
3.04
2.0
1.9
—
—
—
0
0
72
482
1.52
2.84
2.9
2.2
10.32
10.55
g/l
0.16
62
413
61
394
1.58
2.82
2.3
2.1
35.76
36.37
g/l
0.35
51
328
288
2409
1.25
2.79
6.6
4.9
0.00
0.00
estimate
-0.00
61
791
11
34
3.25
2.73
1.2
1.0
39.16
50.08
mg/l
0.36
11
28
69
468
1.50
2.59
1.2
1.2
—
—
—
0
0
140
1077
1.34
2.58
2.7
2.5
65.67
65.55
g/l
0.06
121
959
151
1175
1.32
2.58
2.5
2.6
4.78
6.02
ug/l
0.97
120
996
23
114
2.04
2.57
1.3
2.1
0.72
1.88
g/24h
—
6
58
149
1888
0.76
2.53
4.2
3.6
—
—
—
0
0
20
95
2.12
2.49
1.1
1.1
37.16
33.73
mmol/l
0.35
14
79
75
523
1.46
2.47
2.5
3.3
3.94
6.57
e9/l
2.07
58
357
91
658
1.41
2.47
1.4
1.7
1.48
1.53
g/l
0.21
77
567
48
305
1.60
2.41
1.4
1.4
—
—
—
0
0
6
12
5.02
2.40
2.2
1.1
—
—
—
0
0
9
27
3.35
2.39
1.4
1.4
—
—
—
0
0
15
64
2.36
2.39
1.4
1.1
—
—
—
0
0
10
33
3.05
2.36
1.1
1.0
306.80
254.61
mg/l
—
10
28
86
623
1.41
2.32
1.3
1.4
—
—
—
0
0
10
34
2.96
2.28
2.3
3.2
—
—
—
0
0
18
86
2.11
2.23
1.3
1.2
—
—
—
0
0
303
3490
0.83
2.20
2.1
2.4
—
—
—
0
0
63
436
1.47
2.18
2.6
3.1
1.64
1.75
ratio
—
5
36
7
20
3.51
2.05
2.0
2.3
38428.57
38330.25
ug/l
—
7
20
6
15
4.01
2.04
2.2
1.2
—
—
—
0
0
92
692
1.35
2.01
5.9
3.6
—
—
—
0
0
5
11
4.56
1.94
2.4
1.2
—
—
—
0
0
6
16
3.76
1.93
2.2
1.2
—
—
—
0
0
6
16
3.76
1.93
2.2
1.2
—
—
—
0
0
6
16
3.76
1.93
2.2
1.2
—
—
—
0
0
6
16
3.76
1.93
2.2
1.2
—
—
—
0
0
7
172
0.40
1.91
2.3
2.8
—
—
—
0
0
50
718
0.68
1.90
2.9
3.9
0.48
0.67
%
0.52
20
273
86
647
1.35
1.89
2.7
2.6
—
—
—
0
0
784
7373
1.16
1.88
3.7
4.2
1.24
1.23
mmol/l
0.08
700
6390
25
144
1.75
1.86
1.8
1.3
—
—
—
0
0
55
386
1.44
1.81
7.8
4.8
—
—
—
0
0
62
446
1.41
1.79
2.6
3.2
74.29
80.04
mg/l
0.05
54
363
273
2372
1.19
1.79
2.2
2.5
—
—
—
0
0
55
766
0.71
1.78
2.9
4.0
0.00
0.11
%
5.28
21
284
13
60
2.18
1.78
1.1
1.2
—
38.40
—
0
5
62
447
1.41
1.77
2.7
3.1
46.98
210.61
mg/l
0.69
54
360
48
330
1.47
1.76
2.4
3.3
25.61
25.27
mmol/l
0.24
48
321
115
912
1.29
1.76
2.8
2.3
—
—
—
0
0
52
364
1.45
1.75
2.8
2.6
4.14
4.28
pmol/l
0.42
41
312
40
267
1.51
1.70
1.7
2.2
125.44
122.29
g/l
0.34
32
192
7
25
2.81
1.65
1.4
1.1
—
—
—
0
0
24
144
1.68
1.58
1.3
1.2
0.72
0.84
nmol/l
0.28
17
117
20
115
1.75
1.53
1.5
1.9
—
—
—
0
0
167
1409
1.21
1.51
1.3
1.2
4.04
1.54
u/ml
0.50
31
329
138
1142
1.23
1.51
2.6
2.3
68.42
67.70
e9/l
0.07
106
897
133
1098
1.24
1.49
4.5
5.7
11.35
12.49
mmol/l
0.93
122
1031
61
806
0.74
1.46
2.9
4.0
0.67
0.93
%
0.49
27
320
44
311
1.43
1.45
5.2
3.6
8.05
7.91
mmol/l
0.11
44
305
18
105
1.72
1.33
1.1
1.3
271.70
271.73
mosm/kgh2o
—
10
75
12
61
1.98
1.33
2.5
1.7
118.42
99.95
umol/l
0.37
12
61
46
623
0.73
1.31
1.6
1.6
—
—
—
0
0
35
242
1.46
1.31
1.1
1.2
—
—
—
0
0
14
76
1.85
1.30
1.1
1.7
—
—
—
0
0
112
924
1.23
1.28
3.0
3.8
1.23
1.22
mmol/l
1.69
100
804
69
538
1.30
1.26
1.3
1.5
—
—
—
0
0
45
329
1.38
1.25
5.1
3.5
1.46
1.68
mmol/l
1.42
45
323
85
1049
0.80
1.24
1.2
1.2
3.29
13.93
u/ml
2.99
17
338
20
124
1.62
1.21
1.5
2.0
—
—
—
0
0
6
26
2.31
1.18
1.2
1.5
—
—
—
0
0
105
1257
0.82
1.16
2.8
3.7
3.14
28.92
ug/l
2.87
90
1072
38
275
1.39
1.14
16.5
13.6
—
—
—
0
0
0
36
0.00
1.14
0.0
1.6
—
4.39
—
0
18
12
65
1.85
1.13
2.6
3.8
—
—
—
0
0
17
103
1.66
1.13
1.6
1.2
277.00
338.02
nmol/l
0.36
11
82
15
89
1.69
1.08
1.0
1.1
—
—
—
0
0
57
447
1.29
1.04
4.2
3.2
0.79
0.84
nmol/l
0.49
44
350
56
707
0.78
1.02
2.6
4.0
0.10
0.56
%
0.62
20
229
26
180
1.45
1.01
1.6
1.4
—
—
—
0
0
32
436
0.73
1.00
1.3
1.2
—
—
—
0
0
33
240
1.38
0.99
1.8
1.5
23389.04
15570.69
e6/l
0.28
23
165
34
249
1.38
0.98
4.9
4.0
31.60
32.75
mg/l
0.05
24
171
0
29
0.00
0.97
0.0
1.2
—
1.36
—
0
18
5
101
0.49
0.89
1.2
1.9
—
—
—
0
0
77
639
1.22
0.89
7.2
4.0
—
—
—
0
0
102
1190
0.84
0.89
1.3
1.4
—
—
—
0
0
9
154
0.58
0.88
1.0
1.4
—
—
—
0
0
16
241
0.66
0.88
1.1
1.2
—
—
—
0
0
50
625
0.79
0.87
1.3
1.4
—
—
—
0
0
49
389
1.27
0.85
2.2
2.5
—
15.22
—
0
21
44
554
0.79
0.82
3.6
3.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
75.41
—
0
19
6
33
1.82
0.79
1.5
1.5
70.67
117.89
ug/l
—
6
28
0
25
0.00
0.79
0.0
1.6
—
9.86
—
0
19
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
42
334
1.27
0.74
2.7
3.3
—
—
—
0
0
11
172
0.64
0.74
5.0
3.0
4.74
4.87
e9/l
0.06
11
172
68
575
1.19
0.69
1.8
2.7
11.59
10.86
g/l
0.47
63
511
9
59
1.53
0.68
1.4
1.2
—
—
—
0
0
12
180
0.66
0.68
4.8
3.4
57.08
62.70
%
0.50
12
180
275
2558
1.10
0.67
2.8
3.0
3278.40
9285.11
umol/l
1.81
241
2113
20
270
0.74
0.65
1.9
2.4
16.84
15.21
%
—
8
127
65
552
1.19
0.64
1.2
1.4
—
—
—
0
0
26
337
0.77
0.64
1.2
3.1
185.06
97.42
u/ml
0.23
26
328
224
2074
1.10
0.61
2.9
3.5
0.74
0.90
ug/l
1.91
178
1495
0
20
0.00
0.60
0.0
1.1
—
137.02
—
0
20
0
21
0.00
0.60
0.0
2.0
—
2.68
—
0
5
14
97
1.45
0.59
1.1
1.5
564.00
295.00
titre
—
5
12
348
3289
1.08
0.59
3.4
3.8
12.35
10.36
mg/mmol
0.36
246
2107
14
98
1.43
0.56
1.0
1.1
—
—
—
0
0
34
416
0.81
0.54
1.2
1.3
—
—
—
0
0
11
74
1.49
0.53
1.3
1.4
—
—
—
0
0
18
134
1.35
0.53
3.0
3.7
—
—
—
0
0
55
638
0.86
0.51
1.4
1.5
—
—
—
0
0
108
1192
0.90
0.49
1.2
1.2
—
—
—
0
0
139
1274
1.10
0.49
1.5
1.5
3.29
2.74
g/l
1.00
75
683
7
107
0.65
0.48
1.1
1.3
—
—
—
0
0
8
118
0.68
0.46
2.4
2.9
—
—
—
0
0
8
121
0.66
0.45
1.1
1.2
—
—
—
0
0
5
85
0.59
0.45
1.2
1.1
—
—
—
0
0
20
156
1.29
0.45
1.2
1.4
—
—
—
0
0
102
1122
0.90
0.44
1.2
1.2
24.90
40.65
iu/ml
0.74
25
351
9
127
0.71
0.43
2.6
4.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
18
141
1.28
0.40
1.3
1.2
—
—
—
0
0
12
88
1.37
0.40
2.4
3.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
1.53
—
0
19
60
533
1.13
0.38
2.4
2.9
—
—
—
0
0
5
36
1.39
0.38
2.0
1.5
—
—
—
0
0
13
98
1.33
0.37
1.0
1.1
—
—
—
0
0
320
3068
1.06
0.37
2.9
3.1
6.56
6.53
mmol/l
0.05
282
2470
202
1910
1.07
0.36
1.2
1.3
—
—
—
0
0
103
949
1.09
0.35
1.4
1.4
—
—
—
0
0
54
480
1.13
0.35
3.7
4.3
—
—
—
0
0
80
875
0.91
0.34
1.4
1.3
—
—
—
0
0
22
264
0.83
0.33
1.6
2.3
505.30
65.75
ug/min
—
9
155
29
248
1.17
0.32
2.0
1.6
—
—
—
0
0
7
55
1.27
0.30
1.3
1.5
—
—
—
0
0
15
185
0.81
0.30
1.1
1.1
—
—
—
0
0
38
335
1.14
0.29
2.7
4.7
7.42
7.42
ph
0.28
31
302
9
116
0.77
0.27
1.2
1.4
—
—
—
0
0
32
281
1.14
0.26
2.1
4.0
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
73
789
0.92
0.26
5.8
4.6
—
—
—
0
0
28
244
1.15
0.26
1.3
2.4
1.62
1.89
mg/l
0.96
21
207
38
425
0.89
0.26
2.2
3.0
52.70
7789.16
u/ml
0.68
30
360
40
360
1.11
0.24
1.2
1.3
—
—
—
0
0
50
457
1.10
0.23
1.5
1.9
1.55
1.58
g/l
0.02
44
402
41
452
0.90
0.22
1.1
1.2
—
—
—
0
0
7
93
0.75
0.22
1.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
23
201
1.15
0.21
1.4
1.3
103950.36
88218.43
e6/l
0.09
11
123
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
8
102
0.78
0.21
1.1
1.2
—
—
—
0
0
28
250
1.12
0.19
2.1
2.8
—
—
—
0
0
14
119
1.18
0.17
1.0
1.1
—
—
—
0
0
7
61
1.15
0.17
2.0
1.5
—
—
—
0
0
205
1988
1.04
0.17
1.5
1.6
1.33
1.23
mmol/l
1.04
192
1622
63
668
0.94
0.16
1.7
1.8
197.86
168.08
ug/g
0.30
49
495
9
79
1.14
0.15
15.2
22.2
—
—
—
0
0
13
112
1.16
0.14
1.2
1.1
—
—
—
0
0
71
746
0.95
0.14
3.2
3.7
7.42
7.40
ph
—
10
82
32
295
1.09
0.14
2.1
2.9
7.66
7.57
kpa
0.12
32
286
304
3100
0.97
0.13
5.2
4.9
—
—
—
0
0
8
100
0.80
0.13
1.0
1.1
—
—
—
0
0
31
286
1.09
0.13
2.6
4.9
1.85
2.88
mmol/l
2.60
24
191
24
220
1.09
0.12
1.5
1.4
1189.92
1571.71
e6/l
0.44
12
166
10
86
1.16
0.11
1.1
1.2
—
—
nmol/l
—
0
0
36
382
0.94
0.10
2.7
2.2
—
—
—
0
0
73
756
0.96
0.09
3.2
3.7
5.27
5.21
kpa
0.23
68
710
12
107
1.12
0.08
1.3
1.2
—
—
—
0
0
7
64
1.09
0.08
2.3
2.4
—
—
—
0
0
312
3082
1.02
0.08
3.1
3.2
878.45
267.78
mg/l
0.99
225
2017
6
74
0.81
0.07
1.7
1.2
—
—
—
0
0
85
874
0.97
0.07
1.2
1.2
484.44
530.34
titre
0.12
18
205
8
75
1.07
0.07
2.0
1.9
2.65
3.28
ug/l
—
8
68
8
90
0.89
0.06
1.1
1.2
—
—
—
0
0
104
1063
0.98
0.06
4.2
4.7
—
—
—
0
0
29
305
0.95
0.06
1.1
1.1
42.03
126.01
iu/ml
—
9
95
92
901
1.02
0.05
3.9
3.8
—
—
—
0
0
26
273
0.95
0.05
1.6
1.4
190.69
257.20
ug/g
1.30
16
167
16
170
0.94
0.04
3.8
2.4
—
—
—
0
0
33
341
0.97
0.03
1.7
1.2
430.52
211.63
u/ml
0.51
28
306
40
391
1.02
0.02
1.8
2.7
0.59
0.30
g/l
0.37
12
149
16
167
0.96
0.01
1.5
2.6
—
—
—
0
0
54
533
1.01
0.01
1.6
1.8
0.70
2.71
ug/l
1.65
47
454
15
156
0.96
0.00
1.3
1.1
—
—
—
0
0
18
176
1.02
0.00
1.6
1.5
—
—
—
0
0
22
224
0.98
0.00
1.3
1.4
—
—
—
0
0
27
274
0.99
0.00
3.6
2.9
—
—
—
0
0
12
122
0.98
0.00
1.3
1.1
—
—
—
0
0
19
192
0.99
0.00
1.5
1.6
—
—
—
0
0
22
222
0.99
0.00
3.7
1.8
—
—
—
0
0
18
175
1.03
0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
8
87
0.92
-0.00
2.1
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
57
0.88
-0.00
1.4
2.0
1.16
0.94
e9/l
—
5
52
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
76
0.92
-0.00
1.4
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
8
87
0.92
-0.00
1.0
1.1
1.50
1.69
g/l
—
8
78
5
50
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: VD_SC – Vascular dementia (subcortical)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).