Other and unspecified heterotropia

H7_HETEROTRONAS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H50.4 Cause of death: ICD-10 — H50.4 2 out of 7 registries used, show all original rules.	106
4. Check minimum number of events None	106
5. Include endpoints None	106
6. Filter based on genotype QC (FinnGen only)	101

Control definitions (FinnGen only)

Control exclude: H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H50
Name in latin: Heterotropia alia sive non specificata

NAME	H7_HETEROTRONAS
CONTROL_EXCLUDE	H7_OCUMUSCLE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H504
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H504
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other and unspecified heterotropia based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	971	511	459
Only index persons	817	435	382
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.02	0.02	0.01
Median age at first event (years)
Whole population	24.32	23.48	25.22
Only index persons	34.01	31.14	37.28

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	101	62	39
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	54.94	52.15	59.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
106: Matched controls
1060

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H50.4

ICD-10 Finland

Other and unspecified heterotropia

+∞

152.9

106

H50.2

ICD-10 Finland

Vertical strabismus

+∞

35.4

H53.2

ICD-10 Finland

Diplopia

134.2

35.3

XCW99

NOMESCO Finland

Other investigative procedure of eye

13.8

34.4

CEC10

NOMESCO Finland

Recession and resection of extraocular muscle

+∞

18.2

CEC00

NOMESCO Finland

Recession of extraocular muscle

+∞

16.0

H49.1

ICD-10 Finland

Fourth [trochlear] nerve palsy

+∞

13.8

H50.0

ICD-10 Finland

Convergent concomitant strabismus

+∞

13.8

H50.1

ICD-10 Finland

Divergent concomitant strabismus

+∞

12.8

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

6.0

11.1

WX408

NOMESCO Finland

General anesthesy, balanced

3.8

9.8

168

XCK00

NOMESCO Finland

Perimetry

10.3

9.8

CEC60

NOMESCO Finland

Transposition of extraocular muscle with adjustable suture

+∞

9.5

WX002

NOMESCO Finland

Sedation and analgesia

4.2

9.4

Z01.0

ICD-10 Finland

Examination of eyes and vision

4.0

9.2

107

H50.30

ICD-10 Finland

Intermittent esotropy

+∞

8.4

CEC85

NOMESCO Finland

Combined correction of cyclodeviation

+∞

7.4

CEW99

NOMESCO Finland

Other operation on extraocular muscle

+∞

7.4

ZXE10

NOMESCO Finland

More than one and less than three hours

3.0

7.2

234

H50.31

ICD-10 Finland

Intermittent exotropia

+∞

6.3

WX100

NOMESCO Finland

Conjunctival surface anesthesia

3.8

6.3

Z2446

NOMESCO Finland

Social worker

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3019309) Folate [Moles/volume] in Red Blood Cells

128

2.87

5.18

1.4

1.6

1159.83

1179.73

nmol/l

0.04

105

(3018418) pH of Serum or Plasma

225

2.53

4.95

4.4

3.6

7.39

7.40

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

379

2.26

4.07

12.7

8.0

1.23

1.21

mmol/l

0.93

326

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

137

2.42

3.59

3.4

2.6

0.64

0.88

e6/l

0.36

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

4.90

3.53

1.8

1.6

0.24

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

4.69

3.41

2.0

1.6

1.16

1.19

g/l

—

(36304419) Bacteria [Presence] in Urine

221

2.12

3.20

4.0

2.8

—

(40758558) Short blood count panel - Blood

214

2.12

3.16

5.6

7.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

319

2.00

3.01

2.1

1.8

101.14

94.74

pmol/l

0.46

159

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

10.40

3.01

1.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

134

2.25

2.93

3.7

2.7

2.74

3.31

e6/l

0.11

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

287

1.99

2.91

4.2

3.1

—

(3002582) Erythrocytes [#/volume] in Urine

262

2.00

2.89

3.9

3.0

141.54

308.35

e6/l

0.27

202

(3018095) Leukocytes [#/volume] in Urine

315

1.96

2.85

4.2

3.6

81.76

55.93

e6/l

0.21

212

(3037467) Urinalysis macro (dipstick) panel - Urine

595

2.08

2.83

4.5

—

(3030467) Casts [#/volume] in Urine by Automated count

233

1.98

2.72

4.0

2.8

0.28

0.42

e6/l

0.29

171

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.65

2.68

15.6

11.6

24.43

25.06

mmol/l

0.29

(3044640) Blood type and Crossmatch panel - Blood

241

1.90

2.43

2.2

2.3

—

(3044290) Cell count panel - Cerebral spinal fluid

4.33

2.40

2.6

3.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

100

2.23

2.40

1.6

1.7

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

4.82

2.30

1.0

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

3.67

2.09

1.6

1.5

—

(3007164) IgA [Mass/volume] in Serum or Plasma

184

1.88

2.09

1.8

1.5

1.81

2.45

g/l

1.04

108

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.49

2.00

2.1

1.4

—

(36660697) Celiac disease serology panel - Serum

2.33

1.98

1.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

797

2.17

1.98

4.3

5.75

5.90

mmol/l

0.61

723

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

189

1.82

1.91

1.3

0.96

0.73

u/ml

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

872

2.32

1.85

16.9

13.2

28.39

23.33

mg/l

0.66

676

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.71

1.85

29.7

8.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

496

1.67

1.76

8.8

9.6

4.18

e9/l

0.01

437

(3000991) Gas panel - Venous blood

2.19

1.74

22.1

9.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

383

1.64

1.70

2.5

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

2.92

1.68

4.4

4.6

161.71

210.16

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

2.92

1.68

1.3

1.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.62

1.63

1.1

1.3

—

(3048689) Calprotectin [Mass/mass] in Stool

116

1.89

1.63

2.8

1.7

330.58

113.04

ug/g

0.53

(3011288) Drugs identified in Urine by Screen method

2.81

1.61

1.3

1.5

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.40

1.61

1.1

1.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

207

1.70

1.60

2.3

3.7

—

(40768797) Stomach Pathology biopsy report

1.96

1.58

1.2

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

2.70

1.54

3.7

5.1

104.14

91.22

—

(3023511) Choriogonadotropin [Units/volume] in Urine

2.70

1.54

1.3

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.56

1.52

31.1

9.6

23.01

24.47

mmol/l

—

(3018010) Neutrophils/100 leukocytes in Blood

421

1.58

1.49

6.5

6.7

57.47

57.18

0.06

400

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

2.60

1.48

1.1

2.4

314.71

441.57

mg/l

—

(3052851) Hemolysis interference index of Serum or Plasma

2.83

1.45

3.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

187

1.68

1.44

5.2

4.8

20.63

19.19

0.21

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

147

1.72

1.38

1.2

1.3

1.95

18.04

u/ml

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

3.03

1.37

1.2

1.4

—

(3022096) Basophils/100 leukocytes in Blood

398

1.54

1.37

6.4

6.9

0.55

0.61

0.30

376

(3003458) Phosphate [Moles/volume] in Serum or Plasma

107

1.82

1.36

9.2

7.7

1.04

1.10

mmol/l

0.39

(3044889) 12 lead EKG panel

556

1.56

1.36

4.0

3.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

148

1.71

1.34

1.2

1.3

13.86

32.77

iu/ml

—

(3021589) Normoblasts [#/volume] in Blood

413

1.51

1.26

9.7

10.2

0.00

e9/l

0.93

338

(3013115) Eosinophils [#/volume] in Blood

442

1.51

1.26

6.5

7.2

0.20

0.18

e9/l

0.21

391

(3005719) IgG [Mass/volume] in Serum or Plasma

1.95

1.26

3.8

2.5

9.83

9.12

g/l

0.30

(3002256) Pathology report gross observation

1.89

1.24

1.4

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

445

1.49

1.20

4.7

5.5

0.00

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

445

1.49

1.20

3.5

3.9

0.00

estimate

-0.00

103

(3016879) Cocaine [Presence] in Urine

2.14

1.18

1.1

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

179

1.60

1.18

2.6

2.3

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

1.17

0.0

1.7

—

(3049717) Cytology report of Urine Cyto stain

2.57

1.16

4.4

2.2

—

(3006504) Eosinophils/100 leukocytes in Blood

409

1.48

1.15

6.6

7.0

2.94

2.72

0.13

386

(3002030) Lymphocytes/100 leukocytes in Blood

429

1.47

1.14

6.7

7.0

25.99

28.61

0.96

410

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

261

1.51

1.12

2.0

2.2

61.86

55.14

u/l

0.52

238

(3022217) INR in Platelet poor plasma by Coagulation assay

375

1.46

1.07

26.7

13.0

1.11

1.27

inr

1.01

114

(3019069) Monocytes/100 leukocytes in Blood

414

1.45

1.06

6.8

7.3

8.30

8.35

0.05

395

(3000492) Spirometry study

1.81

1.04

1.9

1.5

—

(40761511) CBC panel - Blood by Automated count

916

1.92

1.02

14.1

12.3

—

(3019198) Lymphocytes [#/volume] in Blood

446

1.43

1.01

6.6

6.8

1.79

2.00

e9/l

0.66

401

(3009261) Glucose [Presence] in Urine by Test strip

449

1.41

0.96

3.4

4.0

0.00

estimate

-0.00

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

825

1.60

0.93

4.7

2.73

2.69

mmol/l

0.16

757

(3022145) Colonoscopy Study observation

1.70

0.93

1.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

412

1.40

0.93

6.1

7.8

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.98

0.91

34.5

9.5

91.56

94.72

—

(3006315) Basophils [#/volume] in Blood

433

1.39

0.90

6.6

6.7

0.04

e9/l

0.13

377

(3028300) Cannabinoids [Presence] in Urine

1.93

0.89

1.1

1.3

—

(3000764) Benzodiazepines [Presence] in Urine

1.93

0.89

1.1

1.3

—

(3027008) Opiates [Presence] in Urine

1.93

0.89

1.1

1.3

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

805

1.55

0.89

4.0

4.2

1.50

1.44

mmol/l

0.55

743

(3042936) Bacteria identified in Isolate by Culture

113

1.60

0.89

2.2

1.8

—

(3001604) Monocytes [#/volume] in Blood

434

1.39

0.88

6.6

6.7

0.53

0.58

e9/l

0.69

378

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

796

1.52

0.86

15.2

12.1

86.49

83.92

ml/min/173m2

0.46

641

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

775

1.49

0.84

3.8

1.22

1.29

mmol/l

0.38

707

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.62

0.84

1.5

2.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.80

0.0

2.1

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.80

0.0

2.1

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.80

0.0

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.72

0.78

2.0

1.7

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

1.81

0.77

1.2

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

813

1.49

0.76

4.3

4.65

4.56

mmol/l

0.42

755

(3015235) Bicarbonate [Moles/volume] in Capillary blood

2.05

0.73

3.6

5.4

22.50

24.70

mmol/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.60

0.73

6.0

3.3

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.80

0.73

4.9

9.57

8.71

kpa

—

(3023368) Bacteria identified in Blood by Culture

226

1.39

0.72

5.3

4.1

—

(3022313) Gas panel - Capillary blood

1.60

0.72

5.8

4.5

—

(3045414) Leukocytes [Presence] in Urine

1.76

0.71

1.9

1.7

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.89

0.69

1.8

1.1

3.08

2.97

g/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

138

1.46

0.68

3.0

2.1

10.82

13.66

umol/l

1.07

129

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.55

0.68

1.4

1.9

—

(3027944) Amphetamines [Presence] in Urine

1.63

0.66

1.1

1.3

—

(3019225) pH of Specimen

1.65

0.64

9.4

4.3

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.54

0.64

22.1

7.9

5.52

5.08

kpa

0.40

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.70

0.62

1.8

1.1

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.70

0.62

1.8

1.1

7.08

7.48

g/l

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.70

0.62

1.8

1.1

3.58

3.60

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

106

1.48

0.62

2.3

1.7

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.58

0.61

1.1

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.61

0.0

2.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.60

0.0

1.9

—

(40768804) Tissue Pathology biopsy report

327

1.30

0.60

2.4

1.9

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.54

0.60

1.8

324.92

362.47

nmol/l

0.35

(3004588) Protein electrophoresis panel - Serum or Plasma

1.55

0.60

2.6

2.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.66

0.56

2.5

2.1

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.57

0.54

2.7

5.0

0.85

0.94

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.57

0.54

2.7

5.0

0.88

0.69

—

(4200892) Spirometry reversibility

1.54

0.52

2.1

1.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.54

0.52

1.5

1.7

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

137

1.38

0.51

2.6

3.0

1.21

0.73

ug/l

0.36

(3025941) Bacteria identified in Stool by Culture

1.52

0.48

1.3

—

(3009542) Hematocrit [Volume Fraction] of Blood

101

976

1.74

0.47

27.8

19.5

38.72

40.21

1.32

920

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.43

0.46

2.6

6.7

128.43

128.36

g/l

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

131

1.35

0.45

3.2

2.0

2.36

2.39

g/l

0.06

122

(3008898) HLA-B27 [Presence]

1.54

0.42

1.0

—

(3026008) Bacteria identified in Urine by Culture

283

1.24

0.41

3.5

2.6

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

0.41

0.0

2.1

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

0.41

0.0

2.1

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

2.1

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

161

1.30

0.41

2.5

3.6

1251.07

244.64

ng/l

0.37

121

(3016502) Oxygen saturation in Arterial blood

1.42

0.40

25.5

8.2

93.88

95.99

0.35

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

143

1.31

0.40

1.9

2.0

—

(1761868) Lipid panel - Serum or Plasma

306

0.80

0.39

3.2

2.8

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.45

0.36

1.3

1.5

—

(3020961) Endomysium IgA Ab [Titer] in Serum

1.35

0.34

1.2

—

(4035726) Immunohistochemistry procedure

1.25

0.28

1.3

1.5

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.31

0.27

3.5

4.7

275.91

269.37

u/l

0.06

(3012516) Albumin [Mass/volume] in Urine

227

1.19

0.27

3.6

3.2

2736.19

100.42

mg/l

0.47

157

(3001019) Free T4 and TSH panel - Serum or Plasma

1.20

0.22

1.2

2.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.9

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.21

0.0

1.3

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

1.46

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

4.0

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.21

0.0

4.7

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.20

0.0

1.7

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.20

0.0

2.5

—

14.71

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.7

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.20

0.0

1.7

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.7

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.7

—

(3003694) ABO and Rh group [Type] in Blood

262

1.15

0.20

1.5

—

(3000330) Specific gravity of Urine by Test strip

1.19

0.20

2.8

3.9

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.26

0.19

4.8

7.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

341

1.13

0.19

3.9

4.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.24

0.18

1.8

—

(3029937) Albumin [Presence] in Urine by Test strip

246

1.13

0.16

4.1

4.0

0.00

estimate

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.14

0.16

2.0

1.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

121

1.18

0.16

1.6

2.3

—

(40761536) Microorganisms panel - Urine sediment

1.15

0.16

6.2

3.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

134

1.14

0.11

1.9

2.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

154

1.12

0.11

1.2

1.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

195

1.10

0.09

2.6

2.0

—

(3022621) pH of Urine by Test strip

0.78

0.08

1.8

2.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

314

1.07

0.08

2.8

3.9

46.20

39.61

ng/l

0.08

218

(40761535) Cells panel - Urine sediment

1.03

0.08

2.0

3.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

194

0.91

0.08

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.82

0.08

1.3

2.1

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

249

1.06

0.04

2.6

3.8

685.10

1222.42

ng/l

1.26

212

(3019832) Treponema pallidum Ab [Presence] in Serum

124

1.06

0.01

1.5

1.8

—

(3013512) EKG study

238

1.01

0.00

3.0

3.7

—

(3020682) Albumin/Creatinine [Ratio] in Urine

244

0.98

0.00

4.3

3.6

5.83

16.47

mg/mmol

1.09

163

(3041096) Erythrocytes [Presence] in Urine by Automated

251

0.99

0.00

4.0

3.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

161

0.99

0.00

2.2

1.7

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

22.14

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.6

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.1

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.3

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.3

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.1

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.6

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.87

0.00

1.4

1.9

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

4.2

—

3.67

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

0.0

5.8

—

111.71

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.1

—

(3045716) Anion gap in Serum or Plasma

0.00

-0.00

0.0

3.3

—

8.15

—

(3021788) Differential panel - Synovial fluid

0.00

-0.00

0.0

1.3

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(3020650) Glucose [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.2

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.8

—

114.28

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

610

1.00

-0.00

3.4

3.1

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.4

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.3

—

(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

0.00

-0.00

0.0

1.0

—

20.78

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.0

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

1.4

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

102.18

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

1.4

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3035509) Tobramycin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

3.6

—

4.44

—

(3000494) Fungus identified in Specimen by Culture

0.92

-0.00

1.4

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

-0.00

0.0

1.6

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.1

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

-0.00

0.0

6.0

—

50.67

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.4

—

(3002619) Bacteria identified in Specimen by Culture

0.00

-0.00

0.0

1.4

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.1

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

3.8

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3032567) Hepatitis B virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

-0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_HETEROTRONAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_HETEROTRONAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_HETEROTRONAS – Other and unspecified heterotropia

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other and unspecified heterotropia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints