Maternal care for cervical incompetence

O15_MATERN_CARE_CERVICAL_INCOMPETENCE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O34.3
  • Hospital discharge: ICD-9 6545|6546
  • Hospital discharge: ICD-8 63494
  • Cause of death: ICD-10 O34.3
  • Cause of death: ICD-9 6545|6546
  • Cause of death: ICD-8 63494

2 out of 7 registries used, show all original rules.

1483

4. Check minimum number of events

None

1483

5. Include endpoints

None

1483

6. Filter based on genotype QC (FinnGen only)

1483

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE_PELVIC_ABNORM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF6v3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10979 10979 -
Only index persons 10647 10647 -
Unadjusted period prevalence (%)
Whole population 0.31 0.31 -
Only index persons 0.39 0.39 -
Median age at first event (years)
Whole population - 29.51 -
Only index persons - 29.48 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1483 1483 -
Unadjusted period prevalence (%) 0.51 0.51 -
Median age at first event (years) 29.69 29.69 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1316
Matched controls
13160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
+∞
323.0
652
*
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
9795.9
323.0
580
*
6545A
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Cervical incompetence[INSUFFICIENTIA CERVICIS UTERI, RASKAUDEN AIKANA]
+∞
147.7
139
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
6.9
144.2
415
825
8702
FHL
Placement of Cerglagen during pregnancy
+∞
128.3
121
*
O60
ICD-10 Finland
Preterm labour and delivery
15.1
117.2
202
156
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
384.3
108.0
107
*
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
+∞
101.4
96
*
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
8.4
77.9
181
244
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
8.6
73.3
168
221
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
6.7
72.7
198
337
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.8
52.3
253
783
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
10.3
51.3
104
109
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
+∞
48.2
46
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.5
46.2
242
792
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.7
43.9
359
1589
Y6099
ICD-8 Finland
Prenatal care and observation
4.0
39.1
169
467
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.5
34.9
177
558
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
3.5
34.3
172
537
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
11.8
31.8
59
52
O30.0
ICD-10 Finland
Twin pregnancy
7.9
30.1
70
93
O20.0
ICD-10 Finland
Threatened abortion
5.4
28.6
88
171
MAB03
NOMESCO Finland
Removal of cerclage of cervix uteri before childbirth
+∞
28.2
27
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.2
25.9
307
1589
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.2
25.6
289
1463
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
8.0
24.4
56
73
N88.3
ICD-10 Finland
Incompetence of cervix uteri
+∞
21.9
21
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
21.8
402
2465
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.3
21.5
215
1017
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
5.8
21.5
62
112
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
4.1
21.0
84
215
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.8
20.8
539
3694
XMA22
NOMESCO Finland
General examination of pregnant woman
3.0
20.4
126
453
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.8
20.0
86
235
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.5
19.8
168
730
63499
ICD-8 Finland
Other complications of pregnancy, Other
4.8
19.7
66
142
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.2
19.5
209
1019
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
11.5
19.5
36
32
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
14.9
19.4
32
22
W84
ICPC
Pregnancy high risk
3.4
18.7
93
287
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
18.5
533
3731
64300
ICD-8 Finland
Spontaneous abortion, With sepsis
9.7
18.4
37
39
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
5.3
17.7
54
105
SPAT1197
SPAT
Extensive health check-up of expecting family
2.0
17.5
271
1537
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.1
17.4
233
1247
SPAT1379
SPAT
Health check-up of pregnant person
2.0
17.2
250
1387
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
16.7
16
*
W78
ICPC
Pregnancy
1.9
16.1
297
1788
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
17.4
15.6
24
14
O32.1
ICD-10 Finland
Maternal care for breech presentation
3.3
15.6
80
253
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.6
15.6
117
471
8502
FHL
Evacuation and abrasion
2.9
15.3
95
344
N97.0
ICD-10 Finland
Female infertility associated with anovulation
4.0
15.1
61
159
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
8.0
14.9
33
42
Z37.2
ICD-10 Finland
Twins, both liveborn
16.7
14.8
23
14
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
6.3
14.2
37
60
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
4.0
14.0
56
145
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
4.1
13.0
50
125
SPAT1380
SPAT
Postpartum check-up
1.9
13.0
207
1175
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.3
13.0
65
203
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.0
12.9
169
892
64394
ICD-8 Finland
NA
70.6
12.6
14
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.3
12.6
63
197
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2.9
12.5
77
278
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.6
12.2
87
343
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
6.2
12.1
32
53
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
7.9
12.1
27
35
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.9
12.1
74
265
O82.0
ICD-10 Finland
Delivery by elective caesarean section
3.6
12.0
54
156
MAA00
NOMESCO Finland
Amniocentesis
4.2
11.9
44
107
66100
ICD-8 Finland
Occipital presentation
5.0
11.5
36
74
O02.1
ICD-10 Finland
Missed abortion
2.4
11.5
95
406
63496
ICD-8 Finland
Other complications of pregnancy, Labores inhibiti
4.6
11.3
38
84
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
7.7
11.2
25
33
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
4.3
11.1
40
95
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.3
10.9
102
464
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.8
10.8
186
1083
B01AB05
ATC
enoxaparin; parenteral
1.6
10.5
362
2568
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
110.9
10.4
11
*
O47.9
ICD-10 Finland
False labour, unspecified
3.8
10.3
42
112
63490
ICD-8 Finland
Other complications of pregnancy, Abortus habitualis
23.6
10.2
14
6
C08CA05
ATC
nifedipine; systemic
2.5
10.2
79
328
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
9.8
213
1334
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
3.1
9.6
51
169
64598
ICD-8 Finland
Other abortion
4.4
9.6
33
76
G02CA02
ATC
buphenine; parenteral
30.2
9.4
12
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.6
9.4
41
117
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
21.9
9.4
13
6
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.4
9.3
76
324
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.1
484
3752
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
9.0
345
2496
O03.5
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by genital tract and pelvic infection
18.7
8.9
13
7
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
5.3
8.9
26
50
W29
ICPC
Pregnancy symptom/complaint other
2.7
8.6
56
213
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.0
8.2
104
544
WX320
NOMESCO Finland
Spinalanesthesy
1.6
8.2
262
1814
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
3.5
8.1
36
105
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.3
8.1
38
116
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.8
8.1
139
811
G02CB01
ATC
bromocriptine; systemic
3.1
8.0
41
133
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
5.1
8.0
24
48
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.4
8.0
27
62
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.0
8.0
104
548
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
5.4
7.8
22
41
N96
ICD-10 Finland
Habitual aborter
5.4
7.8
22
41
63299
ICD-8 Finland
Haemorrhage of pregnancy, Other and unspecified
5.3
7.7
22
42
Q51.2
ICD-10 Finland
Other doubling of uterus
25.2
7.6
10
*
O84.8
ICD-10 Finland
Other multiple delivery
10.1
7.5
14
14
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.5
7.5
55
222
W92
ICPC
Compl labour/ delivery livebirth
2.8
7.4
44
158
65696
ICD-8 Finland
Delivery complicated by malpresentation of foetus, Complete or incomplete breech presentation
5.1
7.4
22
44
N97.9
ICD-10 Finland
Female infertility, unspecified
2.0
7.4
90
462
6225A
ICD-9 Finland
Noninflammatory disorders of cervix, Incompetence of cervix
80.5
7.4
8
*
LDD00
NOMESCO Finland
Suture of cervix uteri
80.5
7.4
8
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.6
7.3
219
1489
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.4
7.2
380
2913
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.5
7.2
53
214
64595
ICD-8 Finland
Other abortion, Haemorrhagia post abortum NUD
7.3
7.2
16
22
W85
ICPC
Gestational diabetes
2.1
7.1
74
356
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
3.9
7.1
27
70
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.0
7.1
38
129
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.1
7.0
36
118
SPAT1196
SPAT
Monitoring of normal pregnancy
1.8
7.0
122
713
MA3AE
NOMESCO Finland
Combined first trimester screening
2.0
6.9
88
460
G03GA01
ATC
chorionic gonadotrophin; parenteral
2.2
6.9
66
309
MBA05
NOMESCO Finland
Curettage of uterus after abortion
4.4
6.9
23
53
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.3
6.8
32
99
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.9
6.7
37
128
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
3.1
6.7
34
111
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.7
528
4334
O72.0
ICD-10 Finland
Third-stage haemorrhage
2.7
6.6
43
163
A02BC01
ATC
omeprazole; systemic
1.4
6.6
314
2355
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
4.2
6.5
23
56
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
5.1
6.5
19
38
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.4
715
6181
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
6.6
6.3
15
23
O36.4
ICD-10 Finland
Maternal care for intrauterine death
6.0
6.3
16
27
N20.1
ICD-10 Finland
Calculus of ureter
3.0
6.3
33
111
63298
ICD-8 Finland
Haemorrhage of pregnancy, Alia definita
11.1
6.3
11
10
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
11.1
6.3
11
10
8703
FHL
Removal of Cerglagen under anesthesia
+∞
6.3
6
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.4
6.2
51
221
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
2.9
6.2
36
127
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
4.5
6.2
20
45
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
6.2
164
1084
B02AA02
ATC
tranexamic acid; systemic
1.5
6.1
226
1611
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
8.6
6.1
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
240
1185
2.22
25.55
4.7
3.8
—
—
—
0
0
509
3622
1.62
16.08
4.1
3.2
—
—
—
0
0
486
3541
1.55
13.34
4.6
4.0
0.0
0.0
estimate
1.08
240
1273
802
6639
1.45
11.09
5.3
4.9
0.0
0.0
estimate
0.50
236
1280
172
1002
1.81
11.06
3.1
2.2
6344.1
6293.1
u/l
0.01
102
434
831
6930
1.45
11.02
4.2
4.1
6.5
6.4
mmol/l
0.42
767
6309
26
58
4.54
10.97
3.3
3.2
—
—
—
0
0
806
6701
1.44
10.75
4.2
3.7
0.0
0.0
estimate
1.08
231
1261
168
987
1.79
10.49
3.6
3.1
1.2
1.2
mmol/l
0.04
147
837
792
6588
1.43
10.38
4.1
3.7
0.0
0.0
estimate
0.50
226
1244
333
2342
1.54
10.30
1.9
1.6
—
—
—
0
0
399
2951
1.48
9.62
2.0
1.7
—
—
—
0
0
1023
8989
1.45
9.48
5.5
4.5
3225.5
1849.9
e6/l
0.23
28
104
267
1827
1.56
9.25
2.2
1.9
—
—
—
0
0
160
965
1.74
9.11
1.5
1.4
—
—
—
0
0
153
923
1.73
8.70
2.5
2.8
—
—
—
0
0
1035
9210
1.41
8.21
5.2
4.4
—
—
—
0
0
507
4017
1.40
8.16
3.4
3.2
29.6
36.0
ng/l
0.18
280
2380
546
4434
1.37
7.39
3.0
2.6
—
—
—
0
0
538
4361
1.37
7.36
3.0
2.8
—
—
—
0
0
50
223
2.29
6.79
3.9
3.1
2.1
2.6
mmol/l
0.91
33
160
323
2443
1.41
6.60
2.5
2.5
8.4
8.5
e6/l
0.06
285
2128
330
2513
1.40
6.47
1.7
1.6
23166494.8
26586399.1
pmol/l
0.05
259
2065
739
6367
1.32
6.42
5.7
3.9
—
—
—
0
0
671
5735
1.31
6.05
10.5
8.6
0.0
0.0
e9/l
0.01
567
4689
435
3500
1.34
5.99
3.0
3.0
307.5
54.1
e6/l
0.71
346
2610
1188
11019
1.39
5.98
16.9
14.8
13.5
13.6
%
0.09
1168
10775
1350
12857
1.56
5.60
13.6
12.0
18.8
20.1
mg/l
0.79
1115
9950
461
3781
1.32
5.47
2.9
2.4
56.1
56.2
u/l
0.02
406
3452
721
6285
1.29
5.37
5.9
5.6
9.5
10.0
umol/l
1.24
658
5917
504
4218
1.30
5.08
2.3
1.6
—
—
—
0
0
50
253
2.01
5.02
4.2
3.6
55.6
57.5
%
0.40
50
253
24
90
2.69
4.76
1.5
1.2
—
—
—
0
0
22
80
2.78
4.62
1.5
1.2
—
—
—
0
0
36
166
2.20
4.61
2.9
2.5
—
—
—
0
0
1348
12912
1.48
4.57
14.1
13.1
3.9
3.9
mmol/l
0.25
1316
12496
499
4216
1.28
4.57
7.1
6.9
1.1
1.1
inr
0.93
211
1283
1345
12882
1.47
4.52
13.9
13.0
139.6
139.6
mmol/l
0.23
1318
12493
14
39
3.61
4.49
1.5
1.2
—
—
—
0
0
47
245
1.95
4.38
3.8
3.4
3.8
4.1
e9/l
0.38
47
245
511
4366
1.26
4.19
3.6
3.5
106.4
85.3
e6/l
0.38
368
2850
283
2242
1.32
4.18
2.4
2.6
503.1
509.0
mosm/kgh2o
0.18
240
1895
1393
13470
1.56
4.11
14.1
11.3
—
—
—
0
0
228
1756
1.35
4.07
2.1
2.3
13.0
13.5
umol/l
0.47
205
1619
21
81
2.62
3.98
1.3
1.8
46.2
50.9
%
—
5
7
644
5673
1.24
3.96
2.0
2.0
—
—
—
0
0
183
1368
1.39
3.93
1.5
1.6
—
—
—
0
0
1170
11020
1.29
3.91
5.0
4.5
14.5
14.6
pmol/l
0.91
1066
10147
64
384
1.70
3.83
1.3
1.2
10.4
12.1
u/l
0.70
58
314
55
317
1.76
3.79
2.4
2.1
5.0
4.5
umol/l
0.23
40
229
42
224
1.90
3.71
1.4
1.3
89.8
111.7
u/ml
0.87
13
48
134
962
1.43
3.64
4.1
4.0
0.0
1.0
%
0.85
25
182
45
248
1.84
3.60
1.5
1.3
—
—
—
0
0
31
151
2.08
3.53
1.5
1.3
—
—
—
0
0
41
221
1.88
3.52
2.6
2.3
—
—
—
0
0
380
3194
1.26
3.49
2.9
2.8
—
—
—
0
0
487
4210
1.23
3.46
5.6
5.6
—
—
—
0
0
229
1807
1.32
3.46
3.3
3.0
0.8
0.8
mmol/l
0.10
214
1682
84
555
1.54
3.44
1.4
1.3
—
—
—
0
0
12
37
3.26
3.34
1.4
1.4
—
—
—
0
0
26
121
2.17
3.33
2.3
1.9
32.5
31.6
pg
0.54
26
121
1022
9542
1.23
3.31
7.4
7.0
74.2
75.2
u/l
0.39
955
8937
133
975
1.40
3.23
3.8
3.7
0.6
0.6
%
0.02
22
171
354
2986
1.24
3.12
1.8
1.8
1.3
1.0
mg/l
1.00
269
2249
112
804
1.43
3.08
1.2
1.3
22.0
24.3
iu/l
0.33
101
678
356
3010
1.24
3.06
4.5
4.2
—
—
—
0
0
185
1442
1.32
3.05
1.3
1.3
—
—
—
0
0
136
1015
1.37
2.99
4.1
3.9
0.2
0.1
%
0.41
26
221
141
1059
1.37
2.98
4.0
3.8
1.1
0.9
%
0.20
26
242
186
1457
1.32
2.97
2.1
2.4
21.5
22.6
%
0.50
150
1236
378
3228
1.23
2.95
3.0
2.9
0.3
0.4
e6/l
0.96
294
2360
27
135
2.02
2.91
1.5
1.9
90.9
90.2
%
0.31
27
135
902
8369
1.20
2.90
3.9
3.3
—
—
—
0
0
32
171
1.89
2.87
1.3
1.3
1.3
1.6
nmol/l
0.56
27
143
225
1817
1.28
2.86
2.2
2.2
105.8
107.4
ug/g
0.03
168
1382
1296
12488
1.30
2.85
5.7
5.3
1.8
1.9
mu/l
1.20
1202
11566
420
3639
1.22
2.83
4.1
3.5
7.4
7.4
ph
0.56
129
668
200
1594
1.29
2.82
2.0
2.3
2.5
2.4
g/l
0.70
177
1475
397
3438
1.21
2.68
2.3
2.0
—
—
—
0
0
491
4341
1.20
2.65
3.1
3.3
2.4
2.4
mmol/l
1.00
434
3799
227
1856
1.26
2.61
1.2
1.2
—
—
—
0
0
122
917
1.36
2.59
2.7
2.8
10.6
10.1
g/l
0.43
112
834
36
208
1.75
2.55
2.4
2.4
15.8
16.4
%
0.29
12
99
20
94
2.14
2.55
1.2
1.1
1.1
1.0
ratio
—
9
39
199
1607
1.28
2.54
2.9
2.0
29.4
29.2
s
0.12
192
1552
92
662
1.42
2.54
1.8
1.5
—
—
—
0
0
19
89
2.15
2.45
1.1
1.2
—
—
—
0
0
71
490
1.47
2.45
2.4
2.1
20.6
20.8
s
0.13
53
427
1056
11075
0.84
2.41
17.2
15.7
332.1
331.2
g/l
2.98
1050
10995
21
104
2.03
2.36
1.7
2.1
1.3
1.3
e9/l
0.07
13
70
95
699
1.38
2.32
1.4
1.6
261.3
303.0
mu/l
1.34
82
615
705
6484
1.17
2.29
3.1
2.8
75.9
78.9
ug/l
0.23
656
6040
41
255
1.63
2.26
3.5
3.6
32.2
20.1
mg/l
0.90
27
154
1015
9621
1.17
2.19
4.2
4.1
11.1
11.6
mm/h
0.65
947
8904
199
1639
1.25
2.17
1.8
1.9
—
—
—
0
0
592
5388
1.16
2.17
5.0
5.0
1.2
1.2
mmol/l
0.42
535
4857
23
411
0.55
2.16
6.4
8.3
—
—
—
0
0
166
1339
1.27
2.16
4.1
4.7
1.0
1.0
mmol/l
0.16
161
1234
1266
12247
1.23
2.13
4.4
4.2
5.7
5.7
mmol/l
0.23
1135
11202
88
650
1.38
2.13
1.9
1.9
—
—
—
0
0
378
3326
1.18
2.10
3.5
3.4
—
—
—
0
0
649
5961
1.16
2.08
5.7
5.7
1.2
1.2
mmol/l
0.70
505
5019
34
207
1.66
2.05
4.5
3.1
—
—
—
0
0
94
709
1.35
2.01
2.0
1.8
1.5
1.4
g/l
0.16
87
639
634
5827
1.15
1.99
5.3
5.7
0.7
0.7
%
0.01
591
5404
105
808
1.32
1.96
1.3
1.2
—
—
—
0
0
325
2838
1.19
1.96
2.2
2.3
3893.3
3725.2
umol/l
0.03
270
2447
86
643
1.36
1.95
1.7
1.4
—
—
—
0
0
307
2672
1.19
1.92
4.5
3.9
—
—
—
0
0
382
3390
1.17
1.90
1.7
1.6
1.3
1.3
mmol/l
0.05
299
2886
85
638
1.35
1.89
1.7
1.4
—
—
—
0
0
655
6051
1.15
1.89
5.5
5.9
8.0
8.1
%
0.51
612
5642
380
3375
1.17
1.87
1.3
1.3
0.7
1.5
u/ml
2.59
99
877
23
129
1.80
1.86
2.7
2.7
—
—
—
0
0
651
6020
1.15
1.83
5.3
5.7
2.8
2.7
%
0.92
605
5571
457
4131
1.15
1.77
3.2
2.1
—
—
—
0
0
34
217
1.58
1.74
1.3
1.2
—
—
—
0
0
12
54
2.23
1.74
1.4
1.6
—
—
—
0
0
672
6255
1.14
1.67
5.3
5.7
29.1
29.2
%
0.12
622
5813
231
1987
1.19
1.66
1.9
1.7
1288.1
1176.8
nmol/l
0.92
175
1468
49
343
1.44
1.65
2.3
1.9
—
—
—
0
0
5
14
3.58
1.61
1.4
1.1
—
—
—
0
0
72
944
0.75
1.60
3.3
3.4
—
—
—
0
0
1451
14354
1.50
1.50
20.8
18.1
90.7
90.6
fl
0.12
1441
14169
44
309
1.44
1.49
1.9
1.7
—
—
—
0
0
1451
14356
1.50
1.47
20.8
18.1
30.1
30.1
pg
0.53
1441
14169
1451
14356
1.50
1.47
20.8
18.2
4.4
4.4
e12/l
0.36
1425
13970
10
45
2.23
1.46
1.4
1.9
8.3
7.4
%
—
10
45
10
45
2.23
1.46
1.4
1.8
—
—
—
0
0
548
5069
1.13
1.46
4.8
4.2
35.8
36.0
g/l
0.40
505
4703
1450
14345
1.49
1.46
20.9
18.2
263.0
264.9
e9/l
0.58
1428
13991
58
430
1.36
1.45
1.8
2.0
1.2
1.5
g/l
1.46
48
383
1451
14358
1.49
1.44
20.9
18.2
7.0
6.7
e9/l
3.57
1425
13966
29
188
1.55
1.43
1.1
1.3
—
—
—
0
0
660
6180
1.12
1.43
5.1
5.5
56.9
56.5
%
0.32
616
5760
123
1011
1.24
1.42
2.6
3.1
4.4
4.5
pmol/l
0.35
114
894
152
1278
1.21
1.42
2.3
2.0
387.7
377.6
nmol/l
0.20
143
1160
16
88
1.83
1.41
1.4
1.9
74.9
75.8
%
0.12
16
83
16
88
1.83
1.41
1.4
1.9
12.2
11.8
%
—
6
40
317
2838
1.15
1.39
3.6
4.1
1.0
1.0
kg/l
0.35
71
446
7
29
2.42
1.39
1.0
1.1
—
—
—
0
0
1451
14363
1.47
1.38
21.0
18.3
132.0
132.1
g/l
0.09
1441
14177
5
120
0.41
1.37
4.2
2.5
—
—
—
0
0
188
1619
1.18
1.36
1.5
1.4
—
—
—
0
0
101
1232
0.81
1.30
3.7
3.7
—
—
—
0
0
33
226
1.47
1.29
1.3
1.3
3.4
4.8
u/ml
0.54
11
98
38
268
1.43
1.28
1.7
1.3
—
—
—
0
0
5
18
2.78
1.28
4.8
3.9
—
—
—
0
0
205
1788
1.17
1.28
2.7
2.7
4.4
4.2
e6/l
0.08
111
897
66
844
0.77
1.27
2.9
3.1
1.6
1.9
mmol/l
0.47
59
693
157
1340
1.19
1.27
2.1
2.2
6.7
6.3
umol/l
0.10
125
1140
5
19
2.64
1.21
1.6
1.1
—
—
—
0
0
30
205
1.47
1.20
1.1
1.3
0.6
0.6
nmol/l
0.46
30
197
13
71
1.84
1.19
1.2
1.7
1.0
2.6
u/field
—
7
53
16
94
1.71
1.17
1.0
1.1
0.2
3.7
u/ml
—
5
26
361
3300
1.12
1.15
4.8
4.0
12.0
8.4
mg/mmol
0.59
197
1924
5
20
2.50
1.15
1.2
1.2
—
—
—
0
0
288
2600
1.13
1.13
1.3
1.3
25.0
31.0
iu/ml
0.35
80
823
22
143
1.55
1.11
1.9
1.6
—
—
—
0
0
112
940
1.21
1.10
1.3
1.3
252.4
170.8
u/ml
0.30
98
864
384
3532
1.12
1.10
3.5
3.2
7.0
6.7
mmol/l
0.49
324
2997
1377
13569
1.21
1.09
10.5
9.7
23.8
23.3
u/l
0.56
1323
13067
33
235
1.41
1.09
1.4
1.7
—
—
—
0
0
23
152
1.52
1.09
4.3
4.0
91.4
117.5
u/ml
—
9
43
56
714
0.78
1.08
5.1
2.4
—
—
—
0
0
7
33
2.13
1.05
1.7
1.1
6.9
5.6
nmol/l
—
7
33
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
14
83
1.69
1.01
1.1
1.2
—
—
—
0
0
32
437
0.73
1.01
1.2
1.2
—
—
—
0
0
129
1110
1.18
0.99
2.6
2.7
1.7
1.8
%
1.30
117
989
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
48
372
1.30
0.96
1.4
1.4
244.1
310.2
ug/g
1.27
23
204
43
557
0.77
0.96
2.0
2.6
135.2
128.2
g/l
1.55
43
543
307
3342
0.90
0.95
5.8
6.5
—
—
—
0
0
20
133
1.51
0.94
1.1
1.1
—
—
—
0
0
30
217
1.39
0.94
1.0
1.3
—
—
—
0
0
28
200
1.41
0.94
1.4
1.2
—
—
—
0
0
35
260
1.35
0.93
1.9
2.2
—
—
—
0
0
70
572
1.23
0.93
1.1
1.1
—
—
—
0
0
10
171
0.58
0.92
1.2
1.0
—
—
—
0
0
26
360
0.72
0.91
2.1
2.8
—
—
—
0
0
38
288
1.33
0.90
1.4
1.3
4.2
21.4
e6/l
1.34
30
220
195
1747
1.13
0.88
1.6
1.5
—
—
—
0
0
73
876
0.82
0.86
1.5
1.4
—
—
—
0
0
14
88
1.60
0.84
5.6
5.9
—
—
—
0
0
30
222
1.36
0.84
1.2
1.1
30.4
2567.0
iu/ml
—
9
51
17
113
1.51
0.82
1.1
1.1
—
—
—
0
0
307
2838
1.10
0.81
1.5
1.5
2.1
2.2
g/l
0.36
182
1684
19
130
1.47
0.81
1.5
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
28.2
—
0
19
296
2736
1.10
0.78
1.6
1.5
21.8
21.9
nmol/l
0.02
245
2323
5
96
0.52
0.78
9.6
12.1
0.5
0.6
mmol/l
—
5
90
75
631
1.20
0.78
3.0
2.8
—
—
—
0
0
338
3149
1.10
0.76
3.8
3.3
258.9
368.9
mg/l
0.21
195
1821
37
288
1.29
0.76
1.6
1.4
849.0
388.2
e6/l
0.26
31
233
9
53
1.70
0.75
1.4
1.8
—
—
—
0
0
339
3163
1.09
0.74
2.2
2.1
2.8
2.9
mg/l
0.07
288
2688
128
1131
1.14
0.74
1.5
1.3
—
—
—
0
0
6
107
0.56
0.72
1.7
1.2
—
—
—
0
0
10
159
0.63
0.72
1.4
1.5
—
21.0
—
0
8
1265
12459
1.10
0.68
4.3
4.1
4.8
4.8
mmol/l
0.13
1164
11577
212
1943
1.11
0.68
1.3
1.4
700.6
607.9
titre
0.16
31
428
367
3454
1.08
0.66
2.1
2.1
183.7
168.2
u/l
0.13
337
3250
269
2498
1.09
0.66
1.2
1.3
6.8
12.9
u/ml
0.99
98
986
38
470
0.80
0.64
1.1
1.6
—
8.9
—
0
9
319
2994
1.08
0.62
3.7
3.4
98.3
96.1
%
0.96
308
2899
8
50
1.60
0.61
1.0
1.0
—
—
—
0
0
33
411
0.80
0.60
1.8
2.3
0.7
0.7
%
0.44
33
393
31
245
1.27
0.60
1.6
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
2.2
—
3.7
—
0
11
184
1691
1.10
0.58
1.3
1.2
—
—
—
0
0
21
159
1.33
0.55
2.4
2.3
—
—
—
0
0
23
177
1.30
0.54
1.0
1.3
—
—
nmol/l
—
0
0
207
1921
1.09
0.54
2.7
2.5
0.7
1.2
e6/l
2.47
114
1026
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
9
63
1.43
0.52
1.0
1.0
—
10.4
—
0
9
9
134
0.67
0.52
1.3
1.3
—
—
—
0
0
9
134
0.67
0.52
1.3
1.3
—
—
—
0
0
9
134
0.67
0.52
1.3
1.3
—
—
—
0
0
9
134
0.67
0.52
1.3
1.3
—
—
—
0
0
24
188
1.28
0.51
3.1
2.3
13.3
13.1
%
0.54
24
188
15
109
1.38
0.51
1.1
1.1
—
—
—
0
0
50
426
1.18
0.50
1.7
1.9
2.5
4.6
iu/l
3.13
15
150
663
6423
1.06
0.50
5.2
5.6
0.0
0.0
e9/l
0.24
569
5594
1254
12385
1.08
0.50
4.3
4.1
1.6
1.6
mmol/l
0.37
1149
11457
21
162
1.30
0.50
1.7
1.3
33.3
33.7
nmol/l
0.01
16
146
15
201
0.74
0.49
2.5
2.5
1.2
1.5
mmol/l
1.25
15
194
31
253
1.23
0.48
1.3
2.3
0.9
0.9
nmol/l
0.11
26
201
771
7510
1.06
0.47
8.2
8.7
4.2
4.0
e9/l
2.68
689
6592
69
607
1.14
0.47
4.2
4.5
—
—
—
0
0
659
6399
1.05
0.45
5.1
5.6
0.6
0.5
e9/l
0.60
567
5575
26
210
1.24
0.45
1.3
1.7
—
—
—
0
0
28
230
1.22
0.42
1.3
1.2
270.6
256.0
u/ml
0.10
21
148
26
212
1.23
0.42
2.7
2.4
70.0
74.8
ug/min
0.03
11
130
96
871
1.11
0.42
1.6
1.7
—
—
—
0
0
16
206
0.77
0.41
2.1
2.2
—
—
—
0
0
8
58
1.38
0.41
2.0
1.6
1.0
1.4
nmol/l
—
8
49
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
141
1520
0.92
0.41
1.5
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
8.1
—
—
—
0
0
1210
11959
1.06
0.40
14.0
13.1
39.2
39.1
%
0.26
855
8933
126
1162
1.09
0.40
1.4
1.4
—
—
—
0
0
16
123
1.30
0.40
1.1
1.2
—
—
—
0
0
21
168
1.25
0.40
1.6
1.3
—
—
—
0
0
33
278
1.19
0.40
1.0
1.1
5.8
4.5
u/ml
0.14
12
133
1278
12656
1.07
0.39
4.7
4.5
2.8
2.8
mmol/l
0.02
1160
11683
24
196
1.23
0.39
1.1
1.2
—
—
—
0
0
5
36
1.39
0.38
1.6
1.2
—
—
—
0
0
26
215
1.21
0.38
1.0
1.0
2.1
2.3
u/ml
0.10
11
105
1198
11849
1.06
0.36
3.8
3.7
1.2
1.2
mmol/l
0.30
1089
10883
235
2233
1.06
0.36
2.8
2.7
2.5
2.4
mmol/l
0.24
205
1952
5
77
0.65
0.35
1.6
1.2
—
—
—
0
0
108
997
1.09
0.35
1.2
1.2
—
—
—
0
0
9
122
0.74
0.35
3.6
2.9
—
—
—
0
0
6
43
1.40
0.35
25.7
22.9
95.2
96.5
ug/l
—
6
34
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
50
443
1.13
0.34
1.2
1.2
—
—
—
0
0
11
82
1.34
0.34
1.3
1.1
—
—
—
0
0
18
145
1.24
0.33
1.3
1.6
—
—
—
0
0
6
45
1.33
0.33
1.3
2.0
28.3
28.2
%
—
6
40
14
109
1.29
0.33
1.3
1.1
160.6
239.6
mg/l
—
9
93
29
339
0.85
0.33
1.1
1.2
—
—
—
0
0
6
46
1.31
0.33
1.0
1.1
—
605.7
—
0
11
6
88
0.68
0.33
1.0
1.4
1.0
0.9
g/l
—
6
88
127
1186
1.08
0.32
2.1
2.2
36.2
36.4
u/l
0.01
106
995
6
47
1.28
0.32
1.3
2.0
17.2
8.9
%
—
6
42
6
47
1.28
0.32
2.3
1.6
—
—
—
0
0
15
187
0.80
0.32
2.5
2.6
7.1
7.3
mmol/l
0.12
15
181
30
348
0.86
0.31
3.1
3.7
17.1
32.6
u/ml
2.02
30
343
113
1209
0.93
0.30
14.3
18.6
1.1
1.2
inr
0.70
19
201
53
477
1.12
0.29
1.1
1.1
—
—
—
0
0
8
108
0.74
0.29
1.0
1.1
—
—
—
0
0
16
130
1.23
0.28
1.8
2.7
—
—
—
0
0
54
488
1.11
0.28
9.2
8.9
—
—
—
0
0
70
642
1.09
0.28
2.6
2.4
—
—
—
0
0
112
1195
0.93
0.28
1.3
1.3
—
—
—
0
0
37
327
1.13
0.28
2.4
1.5
0.6
0.4
nmol/l
0.30
30
272
9
120
0.75
0.27
1.2
1.1
—
—
—
0
0
43
479
0.89
0.27
1.3
1.3
—
—
—
0
0
24
206
1.17
0.26
1.0
1.1
—
—
—
0
0
11
86
1.28
0.26
1.0
1.9
—
7.5
—
0
7
5
71
0.70
0.26
1.0
1.2
6.6
6.7
mmol/l
—
5
64
673
6606
1.03
0.26
5.2
5.6
2.0
2.0
e9/l
0.15
596
5880
9
74
1.22
0.25
1.2
1.1
—
—
—
0
0
52
570
0.91
0.25
1.6
1.6
—
—
—
0
0
14
114
1.23
0.25
1.2
1.2
25.3
36.6
mg/l
—
8
94
31
274
1.13
0.24
1.4
2.0
—
—
—
0
0
5
39
1.28
0.23
1.2
1.3
—
—
—
0
0
86
806
1.07
0.22
3.2
2.6
69.7
73.4
e9/l
0.46
64
588
7
91
0.77
0.22
1.0
1.1
—
—
—
0
0
7
95
0.74
0.22
1.0
1.1
—
12.4
—
0
31
38
420
0.90
0.22
4.8
3.3
—
—
—
0
0
16
135
1.19
0.21
1.8
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
48.5
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
8.8
—
—
—
0
0
0
12
0.00
0.21
0.0
4.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
2.7
—
0
7
5
43
1.16
0.21
1.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
30
268
1.12
0.20
1.0
1.1
2.0
1.4
u/ml
—
7
102
17
145
1.17
0.20
1.4
1.7
53.9
56.8
%
0.11
11
89
107
1127
0.95
0.20
1.4
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
5.5
—
—
—
0
0
6
48
1.25
0.20
1.7
1.5
113.7
133.4
nmol/l
—
6
48
92
973
0.94
0.20
2.3
2.4
15.3
24.1
au/ml
—
6
54
201
2082
0.96
0.20
4.1
3.2
22.0
309.8
ng/l
5.97
112
1394
114
1086
1.05
0.19
3.1
3.3
33.8
52.1
u/ml
1.14
107
1043
6
53
1.13
0.18
1.8
1.7
—
—
—
0
0
58
541
1.08
0.18
1.2
1.2
—
—
—
0
0
676
6666
1.03
0.18
5.4
5.9
0.2
0.2
e9/l
1.80
593
5894
112
1173
0.95
0.18
3.4
4.1
88.3
10.9
ug/l
0.46
88
930
44
406
1.09
0.18
3.3
2.9
0.2
0.3
g/l
0.92
17
135
14
119
1.18
0.17
9.6
7.2
14.1
12.1
mg/l
0.95
14
111
30
272
1.11
0.17
1.5
1.4
23.5
21.8
u/l
0.09
21
232
5
70
0.71
0.16
3.0
1.9
11.4
10.4
%
—
5
70
32
292
1.10
0.16
1.0
1.1
—
—
—
0
0
35
321
1.09
0.16
1.1
1.1
7.2
1.1
u/ml
—
8
118
20
177
1.13
0.16
1.3
1.2
—
—
—
0
0
54
576
0.94
0.16
4.4
3.3
7.4
7.4
ph
—
7
73
8
72
1.11
0.16
1.0
1.1
—
—
—
0
0
40
370
1.08
0.16
3.0
4.4
—
—
—
0
0
6
77
0.78
0.15
2.2
1.5
—
63.7
—
0
9
6
78
0.77
0.15
1.5
1.4
—
—
—
0
0
32
293
1.09
0.15
1.2
1.2
—
—
—
0
0
318
3112
1.03
0.15
3.0
2.1
—
—
—
0
0
9
81
1.11
0.15
1.2
1.1
—
6.7
u/ml
—
0
10
7
88
0.79
0.14
1.1
1.2
—
—
—
0
0
24
264
0.91
0.14
3.7
3.7
—
—
—
0
0
16
180
0.89
0.13
1.3
1.6
—
—
—
0
0
16
180
0.89
0.13
1.4
1.3
—
—
—
0
0
29
268
1.08
0.12
1.5
1.7
5264.2
11057.3
e6/l
1.18
18
194
18
162
1.11
0.12
3.4
2.7
—
—
—
0
0
24
220
1.09
0.11
1.1
1.1
—
—
—
0
0
1119
11244
0.98
0.11
5.9
5.1
39.0
38.5
mmol/mol
1.18
1038
10410
24
221
1.09
0.11
1.1
1.1
—
—
—
0
0
57
544
1.05
0.10
1.5
1.7
—
—
—
0
0
72
748
0.96
0.10
2.3
2.2
7.0
5.8
ug/l
0.14
66
660
21
228
0.92
0.10
1.1
1.2
—
—
—
0
0
79
818
0.96
0.09
1.2
1.4
—
—
—
0
0
94
911
1.03
0.09
2.3
2.6
4.2
4.1
e9/l
0.10
75
740
46
438
1.05
0.09
1.9
2.2
—
—
—
0
0
35
370
0.94
0.09
6.1
4.8
1.0
0.9
%
0.60
35
349
6
55
1.09
0.09
4.7
2.1
25.3
165.7
ug/l
—
6
48
22
204
1.08
0.08
1.0
1.1
1.8
5.2
u/ml
—
6
74
61
587
1.04
0.08
1.2
1.3
236.9
238.2
miu/ml
0.01
30
293
5
60
0.83
0.08
1.4
1.4
—
4.6
—
0
12
10
88
1.14
0.08
2.1
1.2
—
—
—
0
0
11
98
1.12
0.07
1.1
1.1
—
—
—
0
0
6
72
0.83
0.07
1.5
1.1
37.2
33.3
mmol/l
—
6
65
8
78
1.03
0.07
1.0
1.1
—
—
—
0
0
35
367
0.95
0.07
3.1
3.5
346.6
623.6
u/ml
0.31
29
321
19
202
0.94
0.05
1.1
1.0
—
—
—
0
0
125
1271
0.98
0.05
1.2
1.2
77.1
154.9
iu/ml
2.39
38
496
10
110
0.91
0.05
1.7
1.8
—
—
—
0
0
112
1101
1.02
0.05
6.6
6.5
1.1
1.2
mmol/l
0.05
87
865
13
120
1.08
0.05
1.3
1.5
—
—
—
0
0
33
343
0.96
0.05
2.5
3.5
1.2
1.4
mmol/l
0.64
33
338
118
1199
0.98
0.04
1.2
1.2
—
—
—
0
0
75
766
0.98
0.04
7.3
7.3
—
—
—
0
0
15
160
0.94
0.04
2.7
1.7
63.8
59.8
%
0.32
15
160
18
170
1.06
0.04
3.4
5.6
379.3
382.9
umol/l
0.04
13
142
87
856
1.02
0.03
4.0
2.8
66.2
67.0
g/l
0.54
73
780
38
370
1.03
0.03
5.7
4.7
2.0
1.6
%
1.06
38
347
60
589
1.02
0.02
1.5
1.7
—
—
—
0
0
50
510
0.98
0.02
8.7
8.2
24.7
24.3
mmol/l
0.34
50
478
19
182
1.04
0.02
1.1
1.1
—
—
—
0
0
95
959
0.99
0.01
2.7
3.3
87.4
78.2
ng/l
0.29
76
831
48
472
1.02
0.01
1.6
1.6
—
—
—
0
0
489
4902
1.00
0.01
1.8
1.9
101.1
98.6
pmol/l
0.43
236
2383
57
578
0.99
0.01
1.5
1.7
—
—
—
0
0
23
223
1.03
0.01
1.0
1.0
1.4
4.1
u/ml
—
7
75
21
204
1.03
0.00
8.5
6.8
10.4
11.1
mmol/l
0.80
21
186
28
286
0.98
0.00
7.2
3.8
41.1
63.5
mg/l
0.43
22
235
77
764
1.01
0.00
3.0
2.8
150.3
142.9
ng/l
0.10
65
699
10
96
1.04
0.00
2.3
2.2
—
—
—
0
0
10
104
0.96
0.00
1.6
2.1
—
—
—
0
0
22
216
1.02
0.00
6.6
4.1
—
—
—
0
0
11
111
0.99
0.00
1.4
1.2
—
—
—
0
0
12
119
1.01
0.00
1.3
1.5
0.4
0.4
g/l
—
6
84
12
119
1.01
0.00
1.3
1.5
6.5
6.6
g/l
—
6
84
12
119
1.01
0.00
1.3
1.5
2.6
2.9
g/l
—
6
83
59
591
1.00
0.00
1.5
1.7
—
—
—
0
0
313
3129
1.00
0.00
3.5
3.6
—
—
—
0
0
10
103
0.97
0.00
2.5
2.9
—
—
—
0
0
59
587
1.01
0.00
1.5
1.7
—
—
—
0
0
28
285
0.98
0.00
7.2
3.9
36.0
38.2
mg/l
0.10
22
236
19
185
1.03
0.00
1.4
1.6
0.7
0.7
g/l
0.03
13
140
22
225
0.98
0.00
2.3
1.6
—
—
—
0
0
21
205
1.02
0.00
8.5
6.8
104.4
105.5
mmol/l
0.63
21
187
7
70
1.00
0.00
1.0
1.1
1846.6
1524.2
miu/ml
—
7
70
0
5
0.00
0.00
0.0
2.0
—
374.0
—
0
5
0
6
0.00
0.00
0.0
1.2
—
4.7
—
0
6
0
8
0.00
0.00
0.0
1.5
—
193.0
—
0
8
0
7
0.00
0.00
0.0
1.1
—
16.1
—
0
7
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
78
0.90
0.00
1.3
1.5
1.4
1.2
promille
—
7
58
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
5
54
0.93
0.00
1.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
65.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
0.00
2.2
3.7
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
263.0
421.9
u/l
—
5
53
5
53
0.94
0.00
2.8
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
0.00
2.1
3.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_CARE_CERVICAL_INCOMPETENCE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_CARE_CERVICAL_INCOMPETENCE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_MATERN_CARE_CERVICAL_INCOMPETENCE – Maternal care for cervical incompetence

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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