Maternal care for cervical incompetence

O15_MATERN_CARE_CERVICAL_INCOMPETENCE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O34.3
  • Hospital discharge: ICD-9 6545|6546
  • Hospital discharge: ICD-8 63494
  • Cause of death: ICD-10 O34.3
  • Cause of death: ICD-9 6545|6546
  • Cause of death: ICD-8 63494

2 out of 7 registries used, show all original rules.

1523

4. Check minimum number of events

None

1523

5. Include endpoints

None

1523

6. Filter based on genotype QC (FinnGen only)

1462

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE_PELVIC_ABNORM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF6v3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10979 10979 -
Only index persons 10647 10647 -
Unadjusted period prevalence (%)
Whole population 0.31 0.31 -
Only index persons 0.39 0.39 -
Median age at first event (years)
Whole population - 29.51 -
Only index persons - 29.48 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1462 1462 -
Unadjusted period prevalence (%) 0.52 0.52 -
Median age at first event (years) 29.68 29.68 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1523
Matched controls
15230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
+∞
307.7
719
*
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
12600.9
307.7
709
*
O60
ICD-10 Finland
Preterm labour and delivery
16.0
271.4
246
181
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
6.8
250.5
506
1042
6545A
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Cervical incompetence[INSUFFICIENTIA CERVICIS UTERI, RASKAUDEN AIKANA]
+∞
165.7
156
*
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
8.4
141.5
198
267
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
744.0
140.2
136
*
8702
FHL
Placement of Cerglagen during pregnancy
738.0
139.1
135
*
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
8.9
136.8
180
225
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
6.2
115.2
217
400
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
10.3
113.1
131
138
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
1148.8
110.9
107
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.9
90.9
320
975
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.6
81.4
317
1029
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
11.6
67.0
70
63
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.7
66.0
474
2163
O30.0
ICD-10 Finland
Twin pregnancy
8.8
60.9
78
93
O20.0
ICD-10 Finland
Threatened abortion
6.2
59.6
105
179
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
+∞
56.6
54
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
3.4
54.8
224
739
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.4
53.0
213
695
Y6099
ICD-8 Finland
Prenatal care and observation
3.7
52.5
185
554
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
13.8
50.4
47
35
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
7.3
43.4
65
93
W84
ICPC
Pregnancy high risk
3.8
43.4
142
403
64300
ICD-8 Finland
Spontaneous abortion, With sepsis
10.3
38.2
43
43
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
6.3
38.1
65
107
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
4.1
36.5
106
276
XMA22
NOMESCO Finland
General examination of pregnant woman
3.1
34.8
162
572
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.2
33.8
374
1989
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.8
32.3
104
291
SPAT1379
SPAT
Health check-up of pregnant person
2.2
31.9
333
1726
MAB03
NOMESCO Finland
Removal of cerclage of cervix uteri before childbirth
+∞
30.3
29
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.3
30.3
276
1351
63499
ICD-8 Finland
Other complications of pregnancy, Other
4.6
30.1
73
165
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
5.0
29.0
63
130
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.0
28.6
364
2026
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.2
27.6
272
1370
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
6.7
26.9
43
66
N88.3
ICD-10 Finland
Incompetence of cervix uteri
275.7
26.8
27
*
W78
ICPC
Pregnancy
1.9
26.0
409
2438
SPAT1197
SPAT
Extensive health check-up of expecting family
2.0
25.8
346
1953
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
25.5
667
4645
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
6.9
25.1
39
58
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
25.1
24
*
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
4.2
24.6
67
166
O32.1
ICD-10 Finland
Maternal care for breech presentation
3.3
24.4
97
311
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.5
24.4
164
698
N97.0
ICD-10 Finland
Female infertility associated with anovulation
3.8
24.4
75
203
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
23.9
298
1635
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.8
23.8
494
3199
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
3.1
23.5
103
350
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.7
23.0
599
4135
O47.9
ICD-10 Finland
False labour, unspecified
4.1
22.7
64
163
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.7
22.5
74
210
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.2
21.7
201
983
8502
FHL
Evacuation and abrasion
2.9
21.4
103
369
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.8
19.5
103
388
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
3.6
19.1
64
184
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.1
18.3
76
250
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.6
18.3
109
437
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
15.5
18.0
29
19
SPAT1380
SPAT
Postpartum check-up
1.9
17.6
256
1468
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.0
17.6
216
1170
O82.0
ICD-10 Finland
Delivery by elective caesarean section
3.3
17.5
66
205
64598
ICD-8 Finland
Other abortion
4.8
17.3
39
83
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
6.7
17.1
27
41
ZXD00
NOMESCO Finland
Emergency procedure
3.6
17.0
56
159
66100
ICD-8 Finland
Occipital presentation
4.6
16.9
40
89
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.1
16.8
161
795
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
5.2
16.8
34
66
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
7.0
16.6
25
36
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
6.0
16.5
29
49
ZXD05
NOMESCO Finland
Urgent procedure
1.7
16.5
447
3059
N96
ICD-10 Finland
Habitual aborter
6.2
16.4
28
46
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
6.2
16.4
28
46
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
3.4
16.4
59
178
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.8
15.7
35
74
W29
ICPC
Pregnancy symptom/complaint other
2.7
15.5
82
310
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
3.0
15.3
69
239
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.8
15.2
76
278
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.6
15.1
50
143
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
5.0
15.0
32
65
W92
ICPC
Compl labour/ delivery livebirth
3.1
14.9
63
210
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
4.2
14.7
39
95
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.8
14.3
232
1373
O84.8
ICD-10 Finland
Other multiple delivery
24.0
13.8
19
8
64394, ,
ICD-8 Finland
141.2
13.5
14
*
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
141.2
13.5
14
*
B01AB05
ATC
enoxaparin; parenteral
1.6
13.4
450
3215
MAA00
NOMESCO Finland
Amniocentesis
3.3
13.3
50
155
Z37.2
ICD-10 Finland
Twins, both liveborn
9.8
13.2
26
27
ZXE00
NOMESCO Finland
One hour or less
1.5
13.1
583
4422
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
13.1
262
1645
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
13.0
460
3321
C08CA05
ATC
nifedipine; systemic
2.5
12.8
80
328
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.4
12.8
46
139
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
4.7
12.4
28
60
G02CB01
ATC
bromocriptine; systemic
3.4
12.4
44
132
63496
ICD-8 Finland
Other complications of pregnancy, Labores inhibiti
3.4
12.2
43
128
O02.1
ICD-10 Finland
Missed abortion
2.1
12.2
118
585
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
5.3
12.0
24
46
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.3
12.0
45
140
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
11.9
601
4659
63299
ICD-8 Finland
Haemorrhage of pregnancy, Other and unspecified
5.4
11.8
23
43
MAG00
NOMESCO Finland
Assisted breech delivery
5.3
11.6
23
44
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.5
11.5
463
3419
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.5
11.5
38
109
MA3AE
NOMESCO Finland
Combined first trimester screening
1.9
11.2
141
768
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
20.2
11.1
16
8
O36.4
ICD-10 Finland
Maternal care for intrauterine death
10.1
11.0
21
21
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
3.1
10.9
44
143
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
5.4
10.9
21
39
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
3.0
10.7
46
155
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.6
10.6
285
1921
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
5.1
10.5
22
44
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.1
10.4
44
147
O03.5
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by genital tract and pelvic infection
18.9
10.3
15
8
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
3.0
10.2
45
154
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
2.9
10.2
48
171
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.2
10.0
89
427
63490
ICD-8 Finland
Other complications of pregnancy, Abortus habitualis
20.2
9.8
14
7
ULA02
NOMESCO Finland
Kolposcopy
1.7
9.8
211
1346
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.5
9.7
61
252
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
9.2
632
5110
MBA05
NOMESCO Finland
Curettage of uterus after abortion
3.4
9.2
33
100
G03GA01
ATC
chorionic gonadotrophin; parenteral
2.1
9.1
81
389
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
4.8
9.1
20
42
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.5
9.0
56
230
O80.1
ICD-10 Finland
Spontaneous breech delivery
4.2
8.9
23
55
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
8.9
176
1096
WX320
NOMESCO Finland
Spinalanesthesy
1.5
8.8
331
2395
B02AA02
ATC
tranexamic acid; systemic
1.5
8.7
276
1924
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
2.8
8.6
41
147
65696
ICD-8 Finland
Delivery complicated by malpresentation of foetus, Complete or incomplete breech presentation
4.0
8.6
24
61
J01DB01
ATC
cefalexin; oral
1.5
8.5
1233
11271
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
8.5
208
1368
Z31.5
ICD-10 Finland
Genetic counselling
1.9
8.4
106
578
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.6
8.4
46
178
64595
ICD-8 Finland
Other abortion, Haemorrhagia post abortum NUD
4.9
8.4
18
37
6225A
ICD-9 Finland
Noninflammatory disorders of cervix, Incompetence of cervix
+∞
8.3
8
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.8
8.3
128
743
Q51.2
ICD-10 Finland
Other doubling of uterus
10.8
8.3
15
14
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
2.0
8.3
90
466
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
3.4
8.2
29
87
O72.0
ICD-10 Finland
Third-stage haemorrhage
2.4
8.2
53
222
SPAT1263
SPAT
Sampling
1.4
8.1
629
5162
N97.9
ICD-10 Finland
Female infertility, unspecified
1.8
8.1
113
637
Z39.1
ICD-10 Finland
Care and examination of lactating mother
2.4
8.1
53
224
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.5
8.0
47
188
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.5
8.0
48
194
OAA11, ,
SPAT
1.8
7.9
123
717
MBA04
NOMESCO Finland
Curettage of uterus after delivery
4.1
7.8
21
52
W85
ICPC
Gestational diabetes
1.9
7.8
96
520
W03
ICPC
Antepartum bleeding
3.7
7.7
24
66
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
3.6
7.7
25
71
65007
ICD-8 Finland
Delivery without mention of complication, Multiple pregnancy, all presentations
4.5
7.7
18
40
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
25.1
7.6
10
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.0
7.4
78
401
ULC02
NOMESCO Finland
Hysteroscopy
1.9
7.4
93
508
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.2
7.3
63
299
A02BC01
ATC
omeprazole; systemic
1.4
7.1
374
2865
W27
ICPC
Fear of complications of pregnancy
3.3
7.1
26
80
WX402
NOMESCO Finland
General anaesthesia
1.4
7.1
299
2201
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
2.4
7.1
47
200
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
1.7
7.1
134
825
SPAT1196
SPAT
Monitoring of normal pregnancy
1.7
7.0
135
834
SPAT1260
SPAT
Consultation of another employee
1.5
7.0
249
1773
G02CA02
ATC
buphenine; parenteral
11.0
6.8
12
11
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.7
6.8
135
842
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
3.9
6.7
19
49
Z37.1
ICD-10 Finland
Single stillbirth
22.6
6.7
9
*
LDD00
NOMESCO Finland
Suture of cervix uteri
22.6
6.7
9
*
TLW00
NOMESCO Finland
Insemination
2.4
6.6
44
188
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
3.8
6.5
19
50
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.1
6.5
61
301
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
2.5
6.5
38
153
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.0
6.4
28
96
G03DB01
ATC
dydrogesterone; oral
1.5
6.4
252
1831
65200
ICD-8 Finland
Occipital presentation
3.8
6.4
19
51
63899
ICD-8 Finland
Hyperemesis gravidarum, Without mention of neuritis
4.1
6.4
17
42
Z82.7
ICD-10 Finland
Family history of congenital malformations, deformations and chromosomal abnormalities
6.6
6.3
15
23
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
2.9
6.3
28
97
6546B
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Other congenital or acquired abnormality of cervix[MALEFORMATIONES ALIAE CERVICIS UTERI,SYNN AIKANA]
+∞
6.3
6
*
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
6.3
6
*
8703
FHL
Removal of Cerglagen under anesthesia
+∞
6.3
6
*
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
6.3
6.2
15
24
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.8
6.1
30
110
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
6.1
112
686

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
249
1216
2.25
27.28
4.6
3.7
—
—
—
0
0
529
3728
1.64
17.61
4.0
3.2
—
—
—
0
0
507
3625
1.60
15.47
4.5
4.0
0.00
0.00
estimate
1.34
254
1305
835
6809
1.50
13.30
5.2
4.9
0.00
0.00
estimate
0.50
249
1316
370
2529
1.61
13.29
1.9
1.7
—
—
—
0
0
839
6873
1.49
12.90
4.1
3.7
0.00
0.01
estimate
1.08
245
1297
858
7079
1.49
12.60
4.2
4.1
6.49
6.43
mmol/l
0.36
787
6437
436
3138
1.55
12.40
2.0
1.7
—
—
—
0
0
826
6779
1.48
12.35
4.1
3.6
0.00
0.00
estimate
0.75
252
1363
180
1040
1.83
11.89
1.5
1.4
—
—
—
0
0
186
1088
1.81
11.79
3.1
2.2
6213.00
6068.52
u/l
0.03
111
468
1060
9234
1.49
11.07
5.5
4.4
3225.46
1892.69
e6/l
0.22
28
103
169
1001
1.77
10.25
3.6
3.1
1.24
1.24
mmol/l
0.07
148
850
28
70
4.06
10.25
3.2
3.1
—
—
—
0
0
1072
9461
1.45
9.64
5.2
4.3
—
—
—
0
0
273
1886
1.55
9.01
2.2
1.9
—
—
—
0
0
157
948
1.73
8.89
2.5
2.8
—
—
—
0
0
566
4533
1.40
8.58
2.9
2.8
—
—
—
0
0
514
4061
1.40
8.40
3.4
3.1
29.55
35.94
ng/l
0.18
283
2388
772
6551
1.36
8.00
3.4
2.4
—
—
—
0
0
561
4527
1.38
7.98
2.9
2.6
—
—
—
0
0
51
225
2.31
7.09
3.8
3.0
2.07
2.64
mmol/l
0.91
34
160
541
4417
1.35
6.90
2.2
1.7
—
—
—
0
0
337
2549
1.41
6.88
1.7
1.6
22814157.57
26168220.52
pmol/l
0.05
263
2098
331
2501
1.41
6.79
2.5
2.5
8.64
8.69
e6/l
0.02
297
2223
690
5869
1.32
6.55
10.5
8.5
0.00
0.00
e9/l
0.02
584
4798
448
3579
1.36
6.52
3.0
3.0
296.80
53.26
e6/l
0.71
359
2661
28
97
2.92
6.33
1.5
1.2
—
—
—
0
0
1386
13185
1.57
5.93
13.5
11.9
18.76
19.90
mg/l
0.68
1149
10194
1257
11740
1.40
5.86
16.6
14.4
14.37
14.64
%
1.14
1237
11513
25
85
2.97
5.85
1.5
1.2
—
—
—
0
0
53
258
2.09
5.85
4.3
3.6
55.28
57.46
%
0.53
53
258
733
6401
1.28
5.30
5.8
5.5
9.52
10.03
umol/l
1.17
671
6022
468
3858
1.31
5.29
2.8
2.4
56.07
57.65
u/l
0.40
413
3526
50
250
2.03
5.18
3.9
3.4
3.84
4.12
e9/l
0.37
50
250
15
40
3.78
5.09
1.5
1.2
—
—
—
0
0
73
418
1.78
5.05
1.3
1.2
9.84
11.88
u/l
1.06
67
337
62
338
1.87
5.02
2.5
2.0
5.24
4.35
umol/l
0.47
46
241
665
5770
1.27
4.95
2.1
2.0
—
—
—
0
0
38
174
2.21
4.93
2.9
2.5
—
—
—
0
0
528
4468
1.28
4.78
3.6
3.5
103.42
84.06
e6/l
0.36
382
2898
1378
13197
1.46
4.56
14.0
12.9
3.91
3.91
mmol/l
0.32
1345
12766
1431
13813
1.60
4.56
14.1
11.1
—
—
—
0
0
1375
13169
1.45
4.49
13.7
12.8
139.60
139.63
mmol/l
0.21
1347
12766
572
4918
1.26
4.47
9.1
10.6
1.10
1.14
inr
0.98
238
1501
49
258
1.93
4.43
1.5
1.3
—
—
—
0
0
45
234
1.95
4.23
1.4
1.3
89.79
108.83
u/ml
0.71
13
49
1201
11295
1.30
4.16
5.0
4.5
14.50
14.60
pmol/l
0.85
1095
10388
625
5461
1.25
4.16
3.4
3.3
6.15
5.90
ph
1.29
50
397
187
1389
1.39
4.16
1.5
1.6
—
—
—
0
0
435
3664
1.26
3.96
2.3
2.0
—
—
—
0
0
33
157
2.13
3.95
1.5
1.2
—
—
—
0
0
120
831
1.48
3.91
1.2
1.3
20.98
23.89
iu/l
0.47
108
697
231
1798
1.34
3.83
2.1
2.3
13.17
13.56
umol/l
0.38
209
1668
291
2346
1.30
3.75
2.5
2.7
500.92
505.53
mosm/kgh2o
0.13
249
2000
391
3271
1.26
3.74
2.8
2.8
—
—
—
0
0
233
1826
1.33
3.68
3.2
3.0
0.82
0.82
mmol/l
0.04
219
1713
135
982
1.41
3.41
4.1
4.0
0.04
0.85
%
0.82
28
209
189
1453
1.34
3.41
1.3
1.3
—
—
—
0
0
13
37
3.53
3.40
1.4
1.4
—
—
—
0
0
41
224
1.85
3.39
2.6
2.3
—
—
—
0
0
1040
9708
1.22
3.33
7.4
7.0
74.31
74.94
u/l
0.23
972
9105
26
121
2.17
3.33
2.3
1.9
32.54
31.61
pg
0.54
26
121
390
3305
1.24
3.29
2.9
2.9
0.28
0.36
e6/l
0.96
307
2423
1334
12826
1.32
3.23
5.7
5.3
1.75
1.94
mu/l
1.18
1239
11892
361
3041
1.25
3.21
1.8
1.8
1.27
1.00
mg/l
1.04
272
2284
28
137
2.06
3.17
1.5
1.9
91.08
90.25
%
0.40
28
137
134
988
1.39
3.15
3.8
3.7
0.73
0.73
%
0.01
30
259
427
3679
1.22
3.05
4.0
3.5
7.40
7.40
ph
0.48
130
680
105
746
1.44
3.05
1.4
1.6
271.25
305.40
mu/l
1.06
91
656
75
498
1.53
3.04
2.3
2.1
20.53
20.78
s
0.24
57
435
126
927
1.39
3.01
2.6
2.8
10.56
10.15
g/l
0.37
116
844
88
606
1.48
3.00
1.4
1.3
—
—
—
0
0
21
94
2.25
2.97
1.1
1.1
1.10
1.05
ratio
—
9
40
233
1883
1.28
2.93
2.2
2.2
103.72
106.66
ug/g
0.06
174
1442
1083
11409
0.82
2.89
17.0
15.5
332.21
331.27
g/l
3.14
1077
11326
137
1030
1.36
2.88
4.1
4.0
0.14
0.08
%
0.40
29
258
142
1074
1.36
2.87
4.0
3.9
1.28
0.97
%
0.48
34
303
189
1491
1.31
2.86
2.1
2.4
21.56
22.61
%
0.48
152
1265
204
1629
1.29
2.82
2.0
2.3
2.48
2.42
g/l
0.68
180
1505
94
666
1.44
2.79
1.9
1.9
—
—
—
0
0
915
8507
1.19
2.77
3.9
3.3
—
—
—
0
0
100
718
1.42
2.76
1.7
1.5
—
—
—
0
0
204
1635
1.29
2.75
2.9
2.0
29.36
29.22
s
0.11
196
1574
498
4396
1.20
2.73
3.1
3.3
2.35
2.36
mmol/l
1.09
447
3879
231
1885
1.27
2.69
1.2
1.2
—
—
—
0
0
20
93
2.17
2.61
1.1
1.2
—
—
—
0
0
732
6705
1.18
2.56
3.2
2.8
74.24
77.56
ug/l
0.27
681
6237
36
209
1.74
2.51
4.3
3.1
—
—
—
0
0
25
129
1.95
2.51
2.5
2.0
—
—
—
0
0
36
210
1.73
2.48
2.4
2.4
15.80
16.41
%
0.29
12
99
1038
9810
1.18
2.41
4.2
4.1
10.96
11.50
mm/h
0.71
967
9074
473
4203
1.18
2.35
3.3
2.9
28.42
30.55
u/l
0.42
446
3996
203
1668
1.25
2.25
1.8
1.9
—
—
—
0
0
475
4236
1.18
2.24
3.2
2.1
—
—
—
0
0
168
1350
1.27
2.24
4.1
4.7
1.04
1.05
mmol/l
0.21
163
1244
1294
12504
1.23
2.24
4.3
4.2
5.74
5.72
mmol/l
0.20
1158
11436
600
5453
1.17
2.23
4.9
5.0
1.22
1.22
mmol/l
0.45
547
4950
94
696
1.37
2.22
1.7
1.4
—
—
—
0
0
314
2705
1.20
2.20
4.4
3.8
—
—
—
0
0
23
413
0.55
2.19
6.4
8.3
—
—
—
0
0
93
692
1.37
2.14
1.7
1.4
—
—
—
0
0
96
720
1.36
2.11
2.0
1.8
1.52
1.40
g/l
0.15
89
649
672
6179
1.16
2.11
6.6
6.0
—
—
—
0
0
658
6044
1.16
2.09
5.6
5.7
1.23
1.22
mmol/l
0.70
519
5127
41
261
1.59
2.08
3.5
3.6
32.21
20.32
mg/l
0.88
27
157
648
5949
1.16
2.07
5.3
5.7
0.69
0.69
%
0.03
604
5521
382
3373
1.18
2.01
3.4
3.4
—
—
—
0
0
107
824
1.32
1.99
1.3
1.2
—
—
—
0
0
329
2872
1.19
1.98
2.2
2.3
3826.83
3773.89
umol/l
0.01
275
2507
395
3504
1.17
1.96
1.3
1.3
0.73
1.65
u/ml
2.80
104
906
671
6198
1.15
1.93
5.6
5.9
7.99
8.09
%
0.43
627
5783
57
398
1.45
1.91
2.4
2.4
—
—
—
0
0
667
6164
1.15
1.89
5.3
5.7
2.84
2.69
%
1.10
623
5738
23
129
1.79
1.86
2.7
2.7
—
—
—
0
0
236
2016
1.20
1.81
1.8
1.7
1285.39
1174.10
nmol/l
0.93
176
1489
690
6414
1.14
1.76
5.3
5.7
29.17
29.30
%
0.12
646
6007
384
3429
1.16
1.74
1.7
1.6
1.33
1.33
mmol/l
0.01
301
2916
558
5137
1.14
1.62
4.7
4.2
35.75
36.04
g/l
0.61
514
4772
5
14
3.58
1.61
1.4
1.1
—
—
—
0
0
36
238
1.53
1.61
1.4
1.7
—
—
—
0
0
1491
14748
1.52
1.57
20.9
18.1
131.91
132.12
g/l
0.27
1481
14558
1490
14737
1.51
1.56
20.8
18.0
6.99
6.69
e9/l
3.87
1462
14335
1490
14739
1.50
1.54
20.7
17.9
90.61
90.57
fl
0.13
1480
14550
59
434
1.37
1.53
1.8
2.0
1.23
1.50
g/l
1.52
49
387
1490
14740
1.50
1.52
20.7
17.9
30.12
30.07
pg
0.55
1480
14549
1490
14741
1.50
1.51
20.8
18.0
4.41
4.42
e12/l
0.48
1463
14345
1489
14730
1.49
1.50
20.8
18.0
263.13
264.97
e9/l
0.54
1466
14367
46
326
1.42
1.48
2.0
1.7
—
—
—
0
0
10
45
2.23
1.46
1.4
1.9
8.30
7.42
%
—
10
45
10
45
2.23
1.46
1.4
1.8
—
—
—
0
0
155
1301
1.21
1.46
2.3
2.0
391.79
379.02
nmol/l
0.27
146
1179
29
187
1.56
1.46
1.1
1.3
—
—
—
0
0
199
1710
1.19
1.46
1.5
1.5
—
—
—
0
0
677
6340
1.12
1.45
5.0
5.5
56.70
56.49
%
0.18
635
5925
101
1249
0.80
1.44
3.7
3.6
—
—
—
0
0
74
951
0.77
1.44
3.3
3.4
—
—
—
0
0
7
29
2.42
1.39
1.0
1.1
—
—
—
0
0
367
3318
1.14
1.39
4.4
3.8
12.79
8.35
mg/mmol
0.80
201
1928
212
1844
1.17
1.36
1.6
1.5
—
—
—
0
0
325
2919
1.14
1.35
3.5
4.1
1.02
1.02
kg/l
0.32
71
461
125
1036
1.23
1.35
2.6
3.2
4.44
4.51
pmol/l
0.31
115
913
34
232
1.48
1.35
1.3
1.3
3.42
4.73
u/ml
0.50
12
101
39
274
1.43
1.34
1.7
1.3
—
—
—
0
0
1487
14720
1.43
1.33
20.8
17.9
39.54
39.40
%
0.50
1404
13909
67
860
0.77
1.31
2.9
3.1
1.56
1.94
mmol/l
0.50
60
733
160
1365
1.19
1.29
2.0
2.2
6.78
6.22
umol/l
0.12
127
1160
16
91
1.77
1.29
1.4
1.9
74.88
76.00
%
0.15
16
86
16
91
1.77
1.29
1.4
1.9
10.31
13.76
%
1.18
16
86
5
18
2.78
1.28
4.8
3.9
—
—
—
0
0
209
1831
1.16
1.23
2.6
2.7
4.34
4.22
e6/l
0.04
114
917
30
204
1.48
1.23
1.1
1.3
0.59
0.64
nmol/l
0.47
30
196
309
2793
1.13
1.18
3.0
2.8
698.26
814.55
ng/l
0.57
257
2315
55
420
1.32
1.17
1.1
1.1
0.70
4.67
u/ml
—
7
60
60
465
1.30
1.16
1.2
1.2
—
—
—
0
0
1411
13896
1.21
1.16
10.4
9.6
23.80
23.17
u/l
0.69
1355
13369
5
20
2.50
1.15
1.2
1.2
—
—
—
0
0
13
72
1.81
1.15
1.2
1.7
1.00
2.57
u/field
—
7
53
28
191
1.47
1.14
2.8
2.2
13.25
13.10
%
0.44
28
191
56
720
0.77
1.14
5.1
2.4
—
—
—
0
0
50
379
1.33
1.13
1.4
1.4
243.72
312.00
ug/g
1.47
25
209
390
3585
1.12
1.12
3.4
3.2
6.98
6.76
mmol/l
0.46
331
3059
115
966
1.21
1.12
1.3
1.3
245.30
176.05
u/ml
0.25
101
889
32
444
0.71
1.09
1.2
1.2
—
—
—
0
0
5
21
2.39
1.09
1.6
1.0
—
—
—
0
0
132
1128
1.19
1.08
2.6
2.7
1.67
1.82
%
1.24
118
1005
22
145
1.52
1.06
1.9
1.6
—
—
—
0
0
21
137
1.54
1.06
1.0
1.1
—
—
—
0
0
19
121
1.58
1.05
1.2
1.2
0.03
1.40
u/ml
—
5
55
6
122
0.49
1.05
3.7
2.5
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
16
98
1.64
1.03
1.0
1.1
0.22
3.31
u/ml
—
6
30
18
114
1.59
1.02
1.1
1.1
—
—
—
0
0
35
256
1.38
1.01
1.7
1.6
—
—
—
0
0
14
84
1.67
0.98
1.1
1.2
—
—
—
0
0
291
2653
1.12
0.97
1.3
1.3
24.88
30.37
iu/ml
0.32
81
859
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
39
294
1.34
0.95
1.5
1.3
4.16
21.31
e6/l
1.35
31
221
44
567
0.77
0.95
2.0
2.6
135.16
128.35
g/l
1.55
44
553
29
208
1.40
0.94
1.3
1.2
—
—
—
0
0
23
158
1.46
0.94
4.3
3.9
91.21
117.39
u/ml
—
9
43
313
3400
0.90
0.92
5.8
6.5
—
—
—
0
0
10
171
0.58
0.91
1.2
1.0
—
—
—
0
0
131
1137
1.17
0.91
1.5
1.3
—
—
—
0
0
343
3167
1.11
0.91
3.8
3.3
257.02
365.25
mg/l
0.21
199
1841
35
262
1.34
0.90
1.9
2.2
—
—
—
0
0
78
648
1.21
0.89
3.0
2.8
—
—
—
0
0
74
889
0.82
0.88
1.5
1.4
—
—
—
0
0
6
30
2.00
0.87
1.0
1.0
10.50
0.29
u/ml
—
6
22
351
3257
1.10
0.85
2.2
2.1
2.82
2.85
mg/l
0.08
298
2755
21
145
1.45
0.85
1.9
1.9
8.75
33.82
u/ml
0.48
21
145
302
2782
1.11
0.85
1.5
1.5
22.08
21.83
nmol/l
0.10
249
2363
32
239
1.35
0.84
1.3
1.2
260.13
253.82
u/ml
0.04
23
155
27
366
0.73
0.84
2.1
2.8
—
—
—
0
0
14
88
1.60
0.84
5.6
5.9
—
—
—
0
0
38
294
1.30
0.80
1.6
1.4
822.44
384.50
e6/l
0.25
32
236
71
592
1.21
0.80
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
28.20
—
0
19
10
163
0.61
0.78
1.4
1.5
—
21.00
—
0
8
30
226
1.33
0.76
1.2
1.1
30.37
2567.00
iu/ml
—
9
51
19
132
1.44
0.76
1.5
1.3
—
—
—
0
0
9
53
1.70
0.75
2.4
1.5
71.44
89.70
nmol/24h
—
9
53
328
3053
1.09
0.75
3.6
3.4
98.44
96.20
%
1.02
317
2955
30
227
1.33
0.75
1.0
1.3
—
—
—
0
0
6
107
0.56
0.72
1.7
1.2
—
—
—
0
0
38
477
0.79
0.71
1.1
1.6
—
8.88
—
0
9
9
57
1.58
0.71
1.0
1.0
—
—
—
0
0
1290
12700
1.10
0.70
4.3
4.1
4.80
4.81
mmol/l
0.20
1193
11821
315
2938
1.09
0.69
1.5
1.4
2.10
2.17
g/l
0.34
187
1745
9
59
1.53
0.68
1.4
1.8
—
—
—
0
0
372
3498
1.08
0.68
2.1
2.1
182.33
167.25
u/l
0.13
341
3293
24
180
1.34
0.65
1.6
1.3
34.27
33.43
nmol/l
0.04
19
164
188
1720
1.11
0.63
1.3
1.2
—
—
—
0
0
6
101
0.59
0.62
10.7
12.2
0.52
0.64
mmol/l
—
6
95
680
6560
1.07
0.61
5.2
5.6
0.04
0.04
e9/l
0.30
584
5719
213
1967
1.10
0.60
2.6
2.5
0.74
1.22
e6/l
2.57
119
1047
0
22
0.00
0.59
0.0
2.2
—
3.66
—
0
11
272
2541
1.09
0.59
1.2
1.3
6.78
12.75
u/ml
0.99
99
1003
214
1980
1.09
0.58
1.3
1.3
700.65
600.46
titre
0.18
31
436
20
149
1.35
0.58
1.8
2.8
—
—
—
0
0
41
337
1.22
0.57
2.3
1.5
0.56
0.42
nmol/l
0.26
33
282
27
211
1.28
0.57
2.5
2.3
70.04
75.35
ug/min
0.03
11
129
70
606
1.16
0.57
4.2
4.5
—
—
—
0
0
23
176
1.31
0.56
1.0
1.3
—
—
nmol/l
—
0
0
8
55
1.46
0.56
1.5
1.2
16.38
13.96
pmol/l
—
8
42
27
212
1.28
0.55
1.0
1.1
—
—
—
0
0
15
206
0.73
0.55
2.5
2.5
1.16
1.47
mmol/l
1.21
15
199
677
6548
1.06
0.54
5.1
5.6
0.55
0.54
e9/l
0.62
584
5716
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
27
214
1.27
0.52
1.3
1.7
—
—
—
0
0
1279
12626
1.08
0.52
4.2
4.0
1.57
1.58
mmol/l
0.30
1178
11698
883
8617
1.06
0.51
3.1
2.8
34.92
37.34
u/l
0.74
829
8039
9
65
1.39
0.50
1.0
1.0
—
10.05
—
0
10
51
436
1.18
0.50
1.7
2.0
2.51
4.69
iu/l
3.30
15
153
788
7673
1.06
0.49
8.2
8.7
4.21
3.95
e9/l
2.57
705
6733
7
46
1.52
0.48
1.0
1.5
—
—
—
0
0
31
254
1.23
0.47
1.3
2.3
0.93
0.88
nmol/l
0.11
26
202
15
111
1.35
0.46
1.3
1.1
161.80
237.82
mg/l
—
10
96
112
1018
1.11
0.46
1.2
1.2
—
—
—
0
0
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
15
112
1.34
0.44
1.1
1.1
—
—
—
0
0
16
207
0.77
0.42
2.1
2.1
—
—
—
0
0
8
58
1.38
0.41
2.0
1.6
0.98
1.40
nmol/l
—
8
49
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
8.1
—
—
—
0
0
116
1261
0.91
0.40
1.3
1.3
—
—
—
0
0
1303
12900
1.07
0.40
4.7
4.5
2.82
2.83
mmol/l
0.08
1192
11936
27
223
1.21
0.39
1.0
1.0
2.03
2.24
u/ml
0.09
12
110
1222
12078
1.06
0.39
3.8
3.6
1.23
1.21
mmol/l
0.28
1113
11101
21
169
1.25
0.38
1.6
1.3
—
—
—
0
0
16
124
1.29
0.38
1.1
1.2
—
—
—
0
0
5
36
1.39
0.38
1.6
1.2
—
—
—
0
0
33
280
1.18
0.37
1.5
1.4
22.00
21.89
u/l
0.01
23
237
130
1206
1.09
0.37
2.1
2.2
36.19
36.21
u/l
0.00
108
1011
27
225
1.20
0.37
1.1
1.1
—
—
—
0
0
15
116
1.30
0.37
1.3
1.1
25.00
36.54
mg/l
—
9
97
15
191
0.78
0.37
2.5
2.6
7.08
7.26
mmol/l
0.09
15
185
47
412
1.15
0.36
1.1
1.3
4.00
10.99
u/ml
—
5
77
693
6765
1.04
0.36
5.2
5.6
2.02
1.98
e9/l
0.23
617
6050
27
226
1.20
0.36
1.1
1.1
—
—
—
0
0
5
76
0.66
0.35
1.0
1.3
1.44
1.63
g/l
—
5
76
5
77
0.65
0.35
1.6
1.2
—
—
—
0
0
331
3177
1.05
0.35
3.1
2.0
—
—
—
0
0
9
122
0.74
0.35
1.2
1.1
—
—
—
0
0
9
124
0.72
0.35
3.6
2.9
—
—
—
0
0
6
43
1.40
0.35
25.7
22.9
95.17
96.53
ug/l
—
6
34
34
292
1.17
0.34
1.0
1.1
5.36
4.43
u/ml
0.11
13
142
55
490
1.13
0.34
9.0
8.8
—
—
—
0
0
238
2265
1.06
0.34
2.8
2.7
2.45
2.45
mmol/l
0.34
208
1983
98
902
1.09
0.34
1.6
1.7
—
—
—
0
0
130
1212
1.08
0.34
1.4
1.4
—
—
—
0
0
11
82
1.34
0.34
1.3
1.1
—
—
—
0
0
6
45
1.33
0.33
1.0
1.1
—
605.73
—
0
11
43
488
0.88
0.33
1.3
1.3
—
—
—
0
0
605
5900
1.04
0.33
2.3
2.3
77.78
77.65
nmol/l
0.04
548
5348
145
1544
0.93
0.33
1.5
1.4
—
—
—
0
0
6
90
0.67
0.32
1.0
1.4
0.99
0.93
g/l
—
6
90
30
349
0.86
0.32
3.1
3.7
17.07
32.58
u/ml
2.03
30
344
6
47
1.28
0.32
2.3
1.6
—
—
—
0
0
54
484
1.12
0.32
1.1
1.1
—
—
—
0
0
7
99
0.71
0.30
1.0
1.1
—
12.40
—
0
31
24
203
1.19
0.30
1.1
1.2
—
—
—
0
0
7
56
1.25
0.29
1.1
1.5
122.00
147.89
mmol/24h
—
7
56
18
148
1.22
0.29
1.4
1.7
50.67
56.71
%
0.26
12
91
117
1096
1.07
0.29
3.0
3.3
33.23
52.05
u/ml
1.22
110
1053
71
651
1.10
0.28
2.6
2.4
—
—
—
0
0
38
428
0.88
0.28
4.8
3.2
—
—
—
0
0
694
6806
1.04
0.28
5.3
5.9
0.19
0.18
e9/l
1.69
609
6014
88
817
1.08
0.27
3.1
2.6
69.57
73.24
e9/l
0.48
65
595
93
996
0.93
0.26
2.3
2.4
14.39
25.95
au/ml
—
7
79
5
71
0.70
0.26
1.0
1.2
6.62
6.67
mmol/l
—
5
64
9
76
1.19
0.24
1.2
1.2
—
—
—
0
0
53
579
0.91
0.24
1.5
1.6
—
—
—
0
0
115
1216
0.94
0.23
5.6
6.0
105.13
104.22
mmol/l
1.55
115
1216
11
88
1.25
0.22
2.3
1.5
—
—
—
0
0
7
92
0.76
0.22
1.1
1.2
—
—
—
0
0
5
40
1.25
0.22
1.2
1.3
—
—
—
0
0
111
1051
1.06
0.22
2.7
2.1
0.22
0.22
g/l
0.18
106
989
24
273
0.88
0.21
3.8
3.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
48.45
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.18
—
0
5
0
12
0.00
0.21
0.0
4.8
—
—
—
0
0
0
12
0.00
0.21
0.0
8.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
2.67
—
0
7
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
5.3
—
—
—
0
0
112
1179
0.95
0.20
3.4
4.0
88.27
10.92
ug/l
0.46
88
933
6
48
1.25
0.20
1.3
1.9
28.33
28.30
%
—
6
43
9
111
0.81
0.20
1.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.7
1.4
113.73
132.80
nmol/l
—
6
49
6
50
1.20
0.19
1.3
1.9
17.17
9.04
%
—
6
45
14
118
1.19
0.19
9.6
7.2
14.12
12.17
mg/l
0.91
14
110
6
53
1.13
0.18
1.3
1.4
—
—
—
0
0
16
138
1.16
0.17
1.8
1.3
—
—
—
0
0
44
407
1.08
0.17
3.3
2.9
0.18
0.31
g/l
1.04
17
135
205
2113
0.97
0.16
4.1
3.2
21.98
308.08
ng/l
5.96
115
1402
5
70
0.71
0.16
3.0
1.9
11.36
10.43
%
—
5
70
34
311
1.10
0.16
1.2
1.3
—
—
—
0
0
55
587
0.93
0.16
4.4
3.2
7.43
7.41
ph
—
7
73
8
72
1.11
0.16
1.0
1.1
—
—
—
0
0
31
283
1.10
0.16
1.0
1.1
2.03
1.31
u/ml
—
7
110
6
78
0.77
0.15
1.5
1.4
—
—
—
0
0
6
79
0.76
0.15
2.2
1.5
71.50
72.49
umol/l
—
6
79
10
83
1.21
0.15
1.2
1.1
—
6.70
u/ml
—
0
10
327
3202
1.03
0.15
3.5
3.6
—
—
—
0
0
16
182
0.88
0.15
1.3
1.6
—
—
—
0
0
16
182
0.88
0.15
1.4
1.3
—
—
—
0
0
20
179
1.12
0.14
1.3
1.2
—
—
—
0
0
58
549
1.06
0.13
1.2
1.2
—
—
—
0
0
120
1242
0.96
0.13
1.2
1.2
—
—
—
0
0
32
296
1.08
0.13
1.0
1.1
—
—
—
0
0
40
374
1.07
0.13
3.0
4.3
—
—
—
0
0
135
1310
1.03
0.12
1.2
1.2
79.03
156.47
iu/ml
2.51
40
511
72
752
0.96
0.12
2.3
2.2
7.00
5.73
ug/l
0.15
66
664
96
926
1.04
0.11
2.3
2.6
4.11
4.84
e9/l
0.87
79
777
32
298
1.08
0.11
1.3
2.1
—
—
—
0
0
65
621
1.05
0.11
1.2
1.3
230.37
242.20
miu/ml
0.11
32
307
5
46
1.09
0.09
1.4
2.1
44.82
46.82
ug/l
—
5
46
32
340
0.94
0.09
1.1
1.2
—
—
—
0
0
23
213
1.08
0.09
1.0
1.1
1.54
5.14
u/ml
—
7
77
20
184
1.09
0.09
2.5
2.3
27.40
34.27
umol/l
1.33
20
171
18
165
1.09
0.08
3.4
2.7
—
—
—
0
0
6
57
1.05
0.08
4.7
2.3
25.25
159.70
ug/l
—
6
50
82
846
0.97
0.08
1.2
1.4
—
—
—
0
0
75
775
0.97
0.08
7.3
7.3
—
—
—
0
0
35
369
0.95
0.08
3.1
3.5
346.59
620.94
u/ml
0.31
29
323
5
61
0.82
0.08
1.4
1.4
—
4.46
—
0
13
29
273
1.06
0.08
1.5
1.7
5264.17
11059.92
e6/l
1.21
18
199
7
64
1.09
0.08
2.0
3.7
—
—
—
0
0
22
236
0.93
0.08
1.1
1.2
—
—
—
0
0
11
98
1.12
0.07
1.1
1.1
—
—
—
0
0
6
72
0.83
0.07
1.5
1.1
37.17
33.33
mmol/l
—
6
65
113
1104
1.03
0.07
6.5
6.5
1.10
1.17
mmol/l
0.06
88
877
8
75
1.07
0.07
1.0
1.1
1740.25
1554.63
miu/ml
—
8
75
1141
11449
0.99
0.07
5.8
5.1
38.86
38.36
mmol/mol
1.11
1057
10604
8
78
1.03
0.07
1.0
1.1
—
—
—
0
0
7
80
0.87
0.07
1.3
1.5
1.40
1.15
promille
—
7
60
8
93
0.86
0.06
1.0
1.1
—
—
—
0
0
108
1102
0.98
0.06
6.8
6.5
5.05
5.12
kpa
0.32
103
1055
15
162
0.93
0.06
2.7
1.7
63.75
59.76
%
0.32
15
162
61
593
1.03
0.05
1.5
1.8
—
—
—
0
0
496
4992
0.99
0.05
1.8
1.9
100.74
98.49
pmol/l
0.38
239
2431
22
208
1.06
0.05
3.6
2.8
8.24
8.20
kpa
0.05
22
203
10
110
0.91
0.05
1.7
1.8
—
—
—
0
0
35
337
1.04
0.05
1.1
1.1
5.63
2.46
u/ml
0.60
13
169
33
342
0.96
0.04
2.5
3.6
1.21
1.36
mmol/l
0.64
33
337
18
170
1.06
0.04
3.4
5.6
379.31
386.36
umol/l
0.07
13
141
50
513
0.97
0.04
8.7
8.2
24.68
24.36
mmol/l
0.27
50
498
117
1185
0.99
0.03
1.5
1.4
—
—
—
0
0
13
122
1.07
0.02
1.3
1.5
—
—
—
0
0
62
629
0.99
0.02
1.5
1.7
—
—
—
0
0
63
639
0.99
0.02
1.5
1.7
—
—
—
0
0
65
641
1.01
0.01
1.4
1.7
—
—
—
0
0
78
771
1.01
0.01
3.0
2.9
148.12
142.12
ng/l
0.08
66
705
87
862
1.01
0.01
4.0
2.7
66.18
67.00
g/l
0.57
73
786
10
106
0.94
0.01
1.6
2.1
—
—
—
0
0
11
116
0.95
0.00
1.4
1.1
—
—
—
0
0
19
184
1.03
0.00
1.1
1.1
—
—
—
0
0
24
234
1.03
0.00
1.0
1.0
1.45
4.06
u/ml
—
9
101
28
286
0.98
0.00
7.2
3.8
41.14
63.54
mg/l
0.43
22
235
10
104
0.96
0.00
2.5
3.0
—
—
—
0
0
21
206
1.02
0.00
1.0
1.0
—
—
—
0
0
22
216
1.02
0.00
6.6
4.1
—
—
—
0
0
10
102
0.98
0.00
2.3
2.1
—
—
—
0
0
19
188
1.01
0.00
1.4
1.6
0.69
0.71
g/l
0.03
13
144
12
121
0.99
0.00
1.3
1.5
2.59
2.93
g/l
—
6
86
12
121
0.99
0.00
1.3
1.5
0.41
0.35
g/l
—
6
87
12
121
0.99
0.00
1.3
1.5
6.53
6.60
g/l
—
6
87
51
508
1.00
0.00
1.5
1.7
—
—
—
0
0
96
962
1.00
0.00
2.7
3.3
87.10
78.14
ng/l
0.28
77
833
27
271
1.00
0.00
1.0
1.1
0.48
1.65
u/ml
—
7
128
64
643
1.00
0.00
1.5
1.7
—
—
—
0
0
28
285
0.98
0.00
7.2
3.9
35.96
38.24
mg/l
0.10
22
236
48
475
1.01
0.00
1.9
2.3
—
—
—
0
0
22
225
0.98
0.00
2.3
1.6
—
—
—
0
0
5
53
0.94
0.00
2.8
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
16.11
—
0
7
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
374.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
193.00
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
4.67
—
0
6
6
61
0.98
-0.00
1.7
2.3
59.83
52.36
umol/l
—
6
46
6
61
0.98
-0.00
1.0
1.1
244.50
419.24
u/l
—
6
55
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
65.38
—
0
5
5
56
0.89
-0.00
1.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_CARE_CERVICAL_INCOMPETENCE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_CARE_CERVICAL_INCOMPETENCE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_MATERN_CARE_CERVICAL_INCOMPETENCE – Maternal care for cervical incompetence

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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