No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
119 |
4. Check minimum number of eventsNone |
119 |
5. Include endpointsNone |
119 |
6. Filter based on genotype QC (FinnGen only) |
119 |
Control definitions (FinnGen only)
- Control exclude
- AB1_INTESTINAL_INFECTIONS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Shigellosis
based on the number of shared cases.
Similar with more cases:
- Intestinal infectious diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 973 | 504 | 461 |
| Only index persons | 826 | 445 | 381 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 39.41 | 39.06 | 39.80 |
| Only index persons | 36.35 | 36.63 | 36.02 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 119 | 65 | 54 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 42.26 | 38.77 | 46.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 109
- Matched controls
- 1091
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A03.9
ICD-10 Finland
Shigellosis, unspecified
+∞
43.7
39
*
A03.3
ICD-10 Finland
Shigellosis due to Shigella sonnei
+∞
20.4
19
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
12.7
20.2
38
44
A03.0
ICD-10 Finland
Shigellosis due to Shigella dysenteriae
+∞
17.1
16
*
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
+∞
8.4
8
*
A03.1
ICD-10 Finland
Shigellosis due to Shigella flexneri
+∞
7.4
7
*
A03.8
ICD-10 Finland
Other shigellosis
+∞
7.4
7
*
0049X
ICD-9 Finland
Shigellosis, unspecified
+∞
6.3
6
*
J01MA02
ATC
ciprofloxacin; systemic
2.8
6.1
50
251
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42529406) Shigella sp [Presence] in Stool by Culture
21
22
11.38
18.45
3.2
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
17
22
8.85
12.62
2.1
1.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
17
22
8.85
12.62
2.1
1.1
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
22
40
6.52
12.16
1.5
1.1
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
17
37
5.19
7.68
2.6
1.4
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
20
53
4.33
7.15
2.5
1.4
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
10
16
6.73
6.06
1.8
1.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
42
202
2.67
5.73
6.8
4.0
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
24
4.46
3.97
1.0
2.9
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
50
307
2.08
3.63
6.5
5.3
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
59
388
2.03
3.53
7.1
4.9
mmol/l
1.2
1.2
1.63
52
357
(3018095) Leukocytes [#/volume] in Urine
49
305
2.03
3.38
4.5
3.2
e6/l
65.6
50.6
0.19
32
201
(3007853) Bacteria identified in Skin by Aerobe culture
20
85
2.63
3.37
1.9
1.3
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
70
496
2.00
3.34
6.8
6.1
e9/l
0.2
0.2
0.18
60
440
(3002030) Lymphocytes/100 leukocytes in Blood
66
462
1.96
3.22
7.2
5.8
%
27.8
28.6
0.24
61
434
(3037467) Urinalysis macro (dipstick) panel - Urine
82
619
2.04
3.21
5.1
3.4
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
68
482
1.96
3.19
6.7
5.7
e9/l
0.0
0.0
0.00
60
424
(3019198) Lymphocytes [#/volume] in Blood
69
494
1.94
3.11
6.8
5.7
e9/l
1.9
1.8
0.16
60
439
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
60
414
1.91
2.99
9.1
5.6
mmol/l
1.2
1.2
1.15
49
355
(3001604) Monocytes [#/volume] in Blood
67
481
1.90
2.94
6.8
5.7
e9/l
0.6
0.6
0.05
59
421
(3005715) Vancomycin [Mass/volume] in Serum or Plasma
5
6
8.63
2.77
6.0
8.8
mg/l
11.3
9.9
—
5
6
(3003327) Ova and parasites identified in Stool by Light microscopy
9
24
3.97
2.73
2.0
1.6
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
15
63
2.58
2.58
6.6
1.8
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
6
11
5.68
2.57
1.3
1.4
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
8
21
4.01
2.51
2.1
2.5
mg/l
1.6
1.5
—
8
16
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
25
134
2.10
2.51
2.2
1.9
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
35
213
1.91
2.47
1.5
1.3
g/l
3.1
2.4
0.98
21
136
(3037522) Nuclear Ab [Titer] in Serum
23
120
2.14
2.47
1.3
1.3
titre
584.0
365.9
—
5
27
(40760892) CBC W Ordered Manual Differential panel - Blood
36
222
1.89
2.44
4.9
6.0
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
46
308
1.80
2.40
2.0
1.8
pmol/l
95.8
98.5
0.13
26
159
(3022806) Fractional oxyhemoglobin in Capillary blood
5
8
6.46
2.39
1.8
1.3
%
89.1
91.1
—
5
8
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
5
8
6.46
2.39
1.4
2.0
%
88.4
86.4
—
5
8
(3002582) Erythrocytes [#/volume] in Urine
40
259
1.82
2.32
4.1
2.7
e6/l
13.1
312.3
0.59
31
188
(3000991) Gas panel - Venous blood
14
60
2.51
2.32
7.9
7.0
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
89
729
1.88
2.30
9.3
6.8
u/l
82.1
76.1
0.76
82
681
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
12
48
2.67
2.26
7.7
1.7
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
7
19
3.85
2.18
1.9
1.4
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
57
416
1.71
2.16
10.2
9.1
e9/l
0.0
0.0
0.50
47
334
(3013650) Neutrophils [#/volume] in Blood by Automated count
72
562
1.71
2.12
12.3
10.3
e9/l
4.2
4.0
0.24
64
493
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
103
895
2.12
2.11
16.2
10.7
ml/min/173m2
86.4
85.6
0.12
89
721
(3030467) Casts [#/volume] in Urine by Automated count
36
232
1.79
2.10
3.5
2.6
e6/l
0.2
0.3
0.37
25
163
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
5
10
5.16
2.09
1.0
1.2
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
5
10
5.16
2.09
1.2
1.1
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
15
70
2.31
2.08
2.3
1.6
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
46
320
1.71
2.06
13.7
6.5
inr
1.2
1.1
0.16
17
96
(3042936) Bacteria identified in Isolate by Culture
22
122
1.99
2.01
4.2
1.7
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
6
16
3.89
1.96
2.5
1.1
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
11
46
2.53
1.91
1.1
3.0
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
39
264
1.71
1.90
2.2
2.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
17
88
2.09
1.86
2.2
1.8
—
—
—
0
0
(3018418) pH of Serum or Plasma
38
257
1.70
1.85
7.6
3.8
ph
7.4
7.4
—
6
52
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
17
89
2.06
1.81
2.2
1.6
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
13
61
2.27
1.79
3.8
6.6
%
0.2
0.3
—
5
18
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
107
958
2.16
1.77
21.3
11.1
mg/l
26.3
20.6
0.97
92
723
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
18
3.45
1.77
2.7
1.3
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
7
24
3.03
1.75
1.6
1.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
35
235
1.69
1.74
10.4
6.8
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
30
193
1.74
1.74
2.1
1.5
mg/l
1.4
1.2
0.13
21
153
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
6
19
3.27
1.68
1.7
1.7
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
6
19
3.27
1.68
1.0
1.1
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
13
63
2.19
1.67
15.1
3.1
ml/min/173m2
57.8
68.3
—
8
24
(3012544) pH of Venous blood
13
63
2.19
1.67
6.2
3.9
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
5
14
3.68
1.63
1.4
1.4
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
19
108
1.90
1.62
1.4
1.5
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
30
197
1.70
1.61
3.2
3.0
ng/l
1095.5
875.7
0.25
25
170
(3017181) Myelocytes/100 leukocytes in Blood
13
65
2.12
1.55
4.2
6.3
%
0.4
1.0
—
5
20
(3014007) Fractional oxyhemoglobin in Arterial blood
10
45
2.33
1.51
5.4
7.3
%
90.1
93.6
—
10
45
(3013707) Erythrocyte sedimentation rate by Westergren method
83
705
1.59
1.48
4.1
3.6
mm/h
16.1
9.6
1.99
75
651
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
59
466
1.53
1.46
8.4
6.3
umol/l
10.9
11.6
0.21
52
443
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
6
22
2.82
1.45
1.2
1.7
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
16
3.21
1.45
1.4
1.1
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
5
16
3.21
1.45
1.2
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
5
16
3.21
1.45
1.2
1.4
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
33
230
1.60
1.41
2.8
2.5
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
24
154
1.70
1.40
2.0
1.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
36
257
1.57
1.39
1.6
1.4
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
22
138
1.73
1.38
2.1
2.5
e6/l
0.4
1.3
—
10
75
(3043238) Trisomy 21 risk [Likelihood] in Fetus
5
17
3.02
1.37
1.2
1.5
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
17
3.02
1.37
1.2
1.0
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
82
704
1.53
1.31
3.9
3.3
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
18
108
1.79
1.31
1.4
1.3
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
106
969
1.86
1.29
21.9
12.1
mmol/l
139.2
139.9
1.94
101
937
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
8
36
2.31
1.27
1.8
1.6
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
10
49
2.14
1.26
3.9
4.5
mmol/l
25.2
24.7
—
10
49
(3000492) Spirometry study
15
86
1.85
1.26
1.5
1.3
—
—
—
0
0
(3015736) pH of Urine
45
345
1.49
1.24
4.6
3.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
26
176
1.61
1.24
1.2
1.3
iu/ml
9.3
22.5
—
6
59
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
84
730
1.51
1.22
3.6
3.6
pmol/l
14.3
14.7
0.70
74
669
(3023103) Potassium [Moles/volume] in Serum or Plasma
106
973
1.82
1.21
22.1
12.2
mmol/l
3.9
4.0
0.96
101
941
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
38
2.18
1.21
2.4
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
51
403
1.46
1.21
4.1
3.5
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
22
145
1.63
1.16
3.2
2.9
ng/l
1572.9
125.2
0.43
14
100
(3005322) IgE [Units/volume] in Serum or Plasma
10
51
2.05
1.15
1.0
1.2
u/ml
210.8
187.1
—
10
46
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
8
40
2.07
1.14
2.0
2.4
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
8
40
2.07
1.14
3.5
1.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
15
89
1.78
1.14
4.5
3.1
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
28
198
1.54
1.11
4.9
3.1
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
31
225
1.51
1.10
1.5
1.2
u/ml
10.0
1.2
—
7
55
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
9
46
2.03
1.06
5.9
7.2
%
0.7
0.7
—
9
46
(46235355) HIV 1 and 2 tests - Meaningful Use set
26
183
1.54
1.06
3.3
2.0
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
9
47
1.99
1.05
5.9
7.1
%
1.0
1.6
—
9
47
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
5
22
2.33
1.04
1.2
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
5
22
2.33
1.04
1.2
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
5
22
2.33
1.04
1.2
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
5
22
2.33
1.04
1.2
1.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
39
300
1.45
1.04
4.1
2.8
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
20
134
1.59
1.00
1.6
1.9
%
1.3
1.4
0.36
15
121
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
19
126
1.60
0.99
2.1
2.7
e6/l
2.4
2.8
—
8
63
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
7
36
2.00
0.99
1.4
1.5
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
79
696
1.40
0.94
3.5
2.9
u/l
51.3
44.3
0.26
71
662
(3034770) Mitochondria Ab [Titer] in Serum
6
28
2.20
0.93
1.5
1.1
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
53
439
1.37
0.91
4.6
3.2
estimate
0.0
0.0
0.00
11
83
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
6
29
2.12
0.90
1.0
1.3
g/l
0.2
0.3
—
6
29
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
6
29
2.12
0.90
1.3
1.2
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
8
44
1.88
0.88
1.5
1.8
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
15
97
1.63
0.86
3.1
1.8
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
97
892
1.47
0.85
4.2
4.2
mu/l
1.8
1.9
0.21
86
812
(3019225) pH of Specimen
13
81
1.68
0.85
1.9
4.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
44
357
1.37
0.85
2.0
2.0
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
97
899
1.43
0.75
16.2
11.7
%
39.9
40.6
0.48
75
701
(3028707) Methadone [Presence] in Urine by Screen method
5
25
2.04
0.73
4.0
1.6
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
7
41
1.75
0.71
2.4
2.1
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
7
41
1.75
0.71
4.6
2.9
mmol/l
23.8
25.2
—
7
41
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
26
199
1.39
0.70
1.8
1.6
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
53
454
1.30
0.69
4.6
3.2
estimate
0.0
0.0
0.00
12
79
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
14
95
1.54
0.67
19.1
6.4
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
5
28
1.82
0.67
4.6
4.0
g/l
0.3
0.2
—
5
12
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
26
202
1.37
0.65
2.5
2.0
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
5
29
1.75
0.64
1.2
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
17
122
1.46
0.64
1.2
1.2
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
5
30
1.70
0.62
1.4
1.1
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
37
306
1.30
0.61
4.7
3.0
ng/l
21.8
51.5
1.16
24
201
(40768443) Skin Pathology biopsy report
6
35
1.75
0.58
1.2
1.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
36
1.70
0.57
6.7
8.6
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
22
170
1.36
0.57
1.2
1.3
u/ml
3.4
10.1
—
10
73
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
6
38
1.61
0.55
1.5
2.1
mg/l
4.4
2.7
—
6
28
(3020564) Creatinine [Moles/volume] in Serum or Plasma
108
1034
1.48
0.54
21.2
13.0
umol/l
79.2
75.4
0.32
108
1034
(3021601) Nitrite [Presence] in Urine by Test strip
51
448
1.24
0.51
6.1
4.4
estimate
0.0
0.0
0.00
11
84
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
92
864
1.29
0.49
5.2
4.8
mmol/mol
38.5
39.1
0.22
83
805
(3017143) Hepatitis C virus Ab [Presence] in Serum
17
130
1.36
0.47
3.2
1.6
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
7
49
1.45
0.47
3.3
1.4
—
—
—
0
0
(3044889) 12 lead EKG panel
67
611
1.22
0.46
3.1
3.4
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
5
31
1.64
0.43
1.6
1.6
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
8
58
1.41
0.42
1.0
1.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
10
71
1.45
0.40
7.3
3.4
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
12
89
1.39
0.39
1.3
1.8
nmol/l
361.9
379.3
0.12
12
79
(3003740) Influenza virus B Ag [Presence] in Specimen
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
9
123
0.71
0.37
1.2
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
76
0.64
0.37
1.8
1.5
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
41
1.49
0.36
1.3
1.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
6
41
1.49
0.36
3.7
1.6
—
—
—
0
0
(3013512) EKG study
29
248
1.22
0.36
4.6
3.5
—
—
—
0
0
(3022313) Gas panel - Capillary blood
6
43
1.42
0.35
4.3
2.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
6
46
1.32
0.33
2.8
4.0
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
7
51
1.40
0.32
3.4
1.5
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
52
1.37
0.32
2.3
2.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
7
52
1.37
0.32
3.3
1.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
7
52
1.37
0.32
3.3
1.4
—
—
—
0
0
(3008898) HLA-B27 [Presence]
7
53
1.34
0.31
1.0
1.1
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
7
53
1.34
0.31
3.3
1.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
11
84
1.34
0.31
1.2
1.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
19
159
1.23
0.29
1.3
1.5
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
25
218
1.19
0.26
2.4
3.3
mg/l
40.8
59.9
0.45
13
141
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
17
144
1.21
0.23
6.4
2.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
29
259
1.16
0.23
3.7
2.9
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
8
100
0.79
0.22
1.6
1.8
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
2.9
—
2.3
—
0
10
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
10
0.00
0.21
0.0
4.6
—
22.8
—
0
10
(3005570) Glucose [Moles/volume] in Urine
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
98
952
1.17
0.21
4.2
4.0
mmol/l
1.4
1.5
1.11
87
881
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
16
137
1.19
0.20
5.9
2.1
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
21
185
1.16
0.19
2.0
2.8
ug/l
0.7
0.7
0.03
11
116
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
98
956
1.14
0.17
4.1
4.0
mmol/l
4.6
4.7
0.22
88
891
(40761536) Microorganisms panel - Urine sediment
9
78
1.17
0.16
3.7
2.9
—
—
—
0
0
(4035726)
10
84
1.21
0.14
1.5
1.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
11
94
1.19
0.13
1.3
1.3
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
26
239
1.11
0.13
3.8
4.3
%
27.8
22.7
0.37
12
111
(3020682) Albumin/Creatinine [Ratio] in Urine
25
230
1.11
0.13
2.9
4.0
mg/mmol
7.7
9.1
0.13
12
152
(1761868) Lipid panel - Serum or Plasma
38
358
1.09
0.12
2.5
2.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
11
96
1.16
0.10
1.5
1.6
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
56
1.08
0.09
1.3
1.1
—
—
—
0
0
(4010399)
5
64
0.77
0.08
1.6
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
22
235
0.92
0.08
4.0
2.5
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
19
177
1.09
0.07
2.0
1.6
pmol/l
422.0
451.4
0.21
14
156
(40761511) CBC panel - Blood by Automated count
103
1019
1.08
0.05
20.4
10.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
34
351
0.96
0.04
5.7
3.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
23
239
0.95
0.03
7.8
3.3
estimate
0.0
0.0
0.49
12
82
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
12
112
1.08
0.03
2.3
1.4
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
93
922
1.04
0.02
3.9
3.6
mmol/l
1.5
1.3
1.02
80
849
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
98
973
1.04
0.01
4.3
4.4
mmol/l
2.8
2.8
0.25
88
898
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
93
931
1.00
0.00
3.8
4.0
mmol/l
5.9
5.8
0.26
86
857
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
12
115
1.05
0.00
5.1
4.1
%
28.8
32.2
—
6
78
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
338.2
—
0
5
(3048518) aPTT.lupus sensitive actual/normal (normalized LA screen)
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000012) Reticulocyte production index
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4027681)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3038026) Centromere Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017704) Immunofixation for Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
6.7
—
0.6
—
0
6
(40758292) HTLV I+II Ab panel - Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
68.4
—
0
5
(3023709) Somatotropin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
1.2
—
0
5
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
4.9
—
0
8
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.8
—
1.1
—
0
9
(3051611) Lipemic interference index of Serum or Plasma
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_SHIGELLOSIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_SHIGELLOSIS | 1.403 [0.97, 2.03] | 0.074 |
| Birth year | 0.997 [0.99, 1.01] | 0.426 |
During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 381 females with AB1_SHIGELLOSIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_SHIGELLOSIS | 1.969 [1.19, 3.26] | 0.008 |
| Birth year | 0.99 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 341 males with AB1_SHIGELLOSIS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_SHIGELLOSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.135% | 0.421% |
| 5 | 0.893% | 2.237% |
| 10 | 2.16% | 5.996% |
| 15 | 4.042% | 11.162% |
| 20 | 6.91% | 18.953% |
Relationships between endpoints
↥Index endpoint: AB1_SHIGELLOSIS – Shigellosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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