Late syphilis

AB1_LATE_SYPHILIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A52
  • Hospital discharge: ICD-9 09[2-6]
  • Hospital discharge: ICD-8 09[2-6]
  • Cause of death: ICD-10 A52
  • Cause of death: ICD-9 09[2-6]
  • Cause of death: ICD-8 09[2-6]

2 out of 7 registries used, show all original rules.

461

4. Check minimum number of events

None

461

5. Include endpoints

None

461

6. Filter based on genotype QC (FinnGen only)

461

Control definitions (FinnGen only)

Control exclude
AB1_SEXUAL_TRANSMISSION

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3066 1237 1781
Only index persons 2556 1053 1503
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.05
Only index persons 0.05 0.04 0.06
Median age at first event (years)
Whole population 56.97 58.06 56.39
Only index persons 56.43 56.95 56.07

-FinnGen-

Key figures

All Female Male
Number of individuals 461 181 280
Unadjusted period prevalence (%) 0.10 0.06 0.12
Median age at first event (years) 55.56 53.81 56.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
411
Matched controls
4109
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
7597.0
300.6
252
*
M14.6*E11.6
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic neuropathic
1419.7
114.3
106
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
32.5
102.2
137
62
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
1194.5
99.4
93
*
A10AE04
ATC
insulin glargine; parenteral
13.9
96.6
187
233
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
45.4
96.1
118
36
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
15.9
93.2
165
166
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
20.5
91.3
143
104
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
15.6
90.3
161
163
M14.6
ICD-10 Finland
Neuropathic arthropathy
1017.7
86.9
82
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
13.8
80.1
150
164
103
Kela drug reimbursment
Diabetes, insulin-treated
7.7
79.3
270
817
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
19.9
77.9
122
85
215
Kela drug reimbursment
Diabetes, non-insulin-treated
7.2
74.0
252
737
S97
ICPC
Chronic ulcer skin
15.1
68.4
120
109
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
19.1
62.3
98
66
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
14.9
61.6
108
96
T89
ICPC
Diabetes insulin dependent
16.4
61.4
103
82
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
83.7
58.0
64
9
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
31.8
57.2
76
29
H3603, E103
ICD-10 Finland
NA
50.7
56.9
68
16
A10AA02
ATC
NA
18.7
55.7
88
59
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
12.9
55.0
103
104
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
31.4
54.8
73
28
A10AE05
ATC
insulin detemir; parenteral
11.2
54.0
109
128
A46
ICD-10 Finland
Erysipelas
6.9
52.9
155
332
NHQ40
NOMESCO Finland
Amputation of toe
30.4
52.9
71
28
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.9
50.8
146
302
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
17.1
50.3
82
59
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
+∞
50.0
47
*
A10AA01
ATC
NA
21.7
49.8
74
41
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
21.7
49.8
74
41
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
19.6
49.3
76
47
CKC12
NOMESCO Finland
Photocoagulation of retina
14.4
49.0
86
74
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
77.3
48.4
54
8
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
41.9
46.8
58
16
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
20.8
46.5
70
40
J01FF01
ATC
clindamycin; systemic
4.9
46.1
203
684
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
29.0
45.7
62
25
C03CA01
ATC
furosemide; systemic
4.8
44.9
198
663
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
15.6
42.9
72
55
H3601, E103
ICD-10 Finland
NA
44.5
41.7
51
13
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
9.1
41.4
93
128
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
47.2
41.4
50
12
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
38.6
40.5
51
15
NH3CG
NOMESCO Finland
Extensive MRI of foot
64.4
40.2
46
8
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
36.2
39.9
51
16
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
57.3
39.5
46
9
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
113.5
38.5
41
*
NH3BG
NOMESCO Finland
MRI of foot
147.2
38.4
40
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
21.0
36.9
55
30
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
7.1
36.0
95
166
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
27.6
35.9
49
20
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
17.2
35.6
57
38
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
56.7
35.1
41
8
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
33.5
34.7
45
15
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
24.0
34.4
49
23
H43.1
ICD-10 Finland
Vitreous haemorrhage
15.6
34.2
57
42
L17
ICPC
Foot/toe symptom/complaint
4.0
34.2
177
649
SPAT1262
SPAT
Handing over of treatment supplies
4.3
34.1
155
504
177
Kela drug reimbursment
Insulin glargine 300 U / ml
19.9
33.7
51
29
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
4.0
33.7
176
646
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.9
33.1
102
217
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
14.6
32.7
56
44
H3601, E113
ICD-10 Finland
NA
18.8
32.4
50
30
M86.6
ICD-10 Finland
Other chronic osteomyelitis
78.5
32.4
36
5
XCK10
NOMESCO Finland
Photography of fundus of eye
5.5
31.3
103
236
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
11.7
31.1
59
58
T90
ICPC
Diabetes non-insulin dependent
3.8
31.0
174
671
H3603, E113
ICD-10 Finland
NA
33.9
31.0
40
13
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
7.5
30.9
77
122
J01MA12
ATC
levofloxacin; systemic
4.2
30.8
140
448
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
25.1
30.7
43
19
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
13.1
30.1
54
47
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
11.6
30.1
57
56
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
13.7
29.2
51
42
A10BA02
ATC
metformin; oral
3.5
28.8
191
825
H04AA01
ATC
glucagon; nasal, parenteral
12.8
28.8
52
46
H36.01
ICD-10 Finland
Diabetic maculopathy
24.5
28.4
40
18
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
46.2
28.2
34
8
H3600, E103
ICD-10 Finland
NA
28.9
27.6
37
14
N18.8
ICD-10 Finland
Other chronic renal failure
13.1
27.5
49
42
R4180
NOMESCO Finland
Podiatric therapy
44.7
27.2
33
8
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
5.2
27.1
92
215
Z49.1
ICD-10 Finland
Extracorporeal dialysis
24.5
27.1
38
17
A10AE06
ATC
insulin degludec; parenteral
9.7
26.8
56
66
WX213
NOMESCO Finland
Lower leg blockade
31.7
26.8
35
12
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
31.7
26.8
35
12
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
16.4
26.7
43
29
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
64.5
26.3
30
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
25.7
105
297
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
25.6
233
1235
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
25.4
25.2
35
15
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
18.9
24.9
38
22
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
18.9
24.9
38
22
H36.00
ICD-10 Finland
Diabetic background retinopathy
23.8
24.8
35
16
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
13.6
24.7
43
35
205
Kela drug reimbursment
Chronic hypertension
3.2
24.5
167
718
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.8
24.4
64
108
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
71.9
24.1
27
*
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
7.6
23.9
58
87
A52.75
ICD-10 Finland
Unspecified syphilis in the mouth
254.1
23.9
24
*
TK800
NOMESCO Finland
Hemodialysis
13.2
23.9
42
35
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
14.2
23.5
40
31
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
26.5
23.4
32
13
TNG34
NOMESCO Finland
Major custom moulded orthopaedic cast, knee or lower leg
21.7
23.4
34
17
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
14.2
22.9
39
30
B03XA02
ATC
darbepoetin alfa; parenteral
13.3
22.8
40
33
CKC15
NOMESCO Finland
Panretinal photocoagulation
29.3
22.6
30
11
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
37.4
22.3
28
8
SPAT1229
SPAT
Assessment of need for aid
5.4
22.3
71
153
WW200
NOMESCO Finland
Immunization
10.5
21.9
43
45
E10
ICD-10 Finland
Type 1 diabetes mellitus
11.8
21.7
40
37
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.8
21.6
104
336
CKD40
NOMESCO Finland
Endophotocoagulation of retina
20.3
21.6
32
17
A12AA04
ATC
calcium carbonate; oral
15.8
21.6
35
24
S91.3
ICD-10 Finland
Open wound of other parts of foot
12.2
21.4
39
35
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
20.8
21.2
31
16
A11CC03
ATC
alfacalcidol; systemic
11.8
21.2
39
36
J01MA02
ATC
ciprofloxacin; systemic
2.8
21.0
210
1130
L84
ICD-10 Finland
Corns and callosities
8.1
20.9
48
66
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.6
20.8
109
374
S18
ICPC
Laceration/cut
2.7
20.7
223
1247
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
5.2
20.6
67
147
CKC10
NOMESCO Finland
Local photocoagulation of retina
13.0
20.5
36
30
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
13.0
20.5
36
30
137
Kela drug reimbursment
Uraemia requiring dialysis
24.9
20.2
28
12
V03AE01
ATC
polystyrene sulfonate; oral
17.5
20.0
31
19
A52.9
ICD-10 Finland
Late syphilis, unspecified
+∞
19.9
19
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.8
19.8
95
304
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.9
19.8
159
740
NH1AD
NOMESCO Finland
Ankle and foot CT
13.6
19.8
34
27
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.9
19.6
147
654
H3600, E113
ICD-10 Finland
NA
17.9
19.5
30
18
TQW11
NOMESCO Finland
Vacuum treatment of wound
12.2
19.4
35
31
Z49.2
ICD-10 Finland
Other dialysis
24.0
19.3
27
12
R60.0
ICD-10 Finland
Localized oedema
4.2
19.3
79
220
Z94.0
ICD-10 Finland
Kidney transplant status
18.2
19.0
29
17
B05DA
ATC
Isotonic solutions
29.4
18.9
25
9
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
18.9
160
763
RJ414
NOMESCO Finland
NA
73.4
18.9
21
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.0
18.8
81
236
L89
ICD-10 Finland
Decubitus ulcer and pressure area
13.8
18.7
32
25
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
16.1
18.7
30
20
C09AA02
ATC
enalapril; systemic
3.0
18.6
126
520
160
Kela drug reimbursment
exenatide
14.5
18.6
31
23
V03AE02
ATC
sevelamer; oral
26.5
18.4
25
10
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
18.4
127
531
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
11.9
18.1
33
30
QDA10
NOMESCO Finland
Incision of skin of lower limb
28.2
18.0
24
9
A10AB06
ATC
insulin glulisine; parenteral
24.1
18.0
25
11
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
24.1
18.0
25
11
B01AB05
ATC
enoxaparin; parenteral
2.7
17.8
161
793
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
+∞
17.8
17
*
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
17.8
17
*
NGQ20
NOMESCO Finland
Amputation of lower leg
22.1
17.5
25
12
J01DA01
ATC
[U] cefalexin; systemic
2.6
17.5
286
1940
J01DB01
ATC
cefalexin; oral
3.3
17.4
361
2822
C02AC05
ATC
moxonidine; oral
6.0
17.4
49
90
WX002
NOMESCO Finland
Sedation and analgesia
3.1
17.4
116
469
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
15.7
17.4
28
19
SPAT1255
SPAT
Intravenous administration of medicine
5.1
17.4
57
126
WX320
NOMESCO Finland
Spinalanesthesy
2.9
17.3
130
571
S20
ICPC
Corn/callosity
11.5
17.3
32
30
Z49.0
ICD-10 Finland
Preparatory care for dialysis
16.9
17.3
27
17
L04AA06
ATC
mycophenolic acid; systemic
14.1
17.2
29
22
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
7.5
17.2
41
60
ZZA00
NOMESCO Finland
Split skin graft
8.0
17.1
39
53
M79.6
ICD-10 Finland
Pain in limb
2.6
17.1
177
936
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.0
17.1
73
210
L28
ICPC
Limited function/disability (L)
3.3
16.9
94
335
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
13.5
16.9
29
23
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
16.9
152
742
X59
ICD-10 Finland
Exposure to unspecified factor
3.0
16.9
117
486
NH1CM
NOMESCO Finland
Ankle and foot extensive MRI examination with 3 Tesla magnet
66.2
16.9
19
*
M14.2*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic arthropathy
+∞
16.8
16
*
NH3CM
NOMESCO Finland
Extensive MRI of foot (more than 1.5 T)
+∞
16.8
16
*
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
7.4
16.7
40
59
A10BX07
ATC
[U] liraglutide; parenteral
21.1
16.6
24
12
A10BB01
ATC
glibenclamide; oral
6.9
16.6
42
67
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.6
16.6
60
147
E66.00
ICD-10 Finland
Metabolic syndrome
5.1
16.5
54
119
127
Kela drug reimbursment
Transplant complication
13.6
16.4
28
22
I10
ICD-10 Finland
Essential (primary) hypertension
2.4
16.4
271
1816
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
31.5
16.3
21
7
196
Kela drug reimbursment
Paricalcitol and cinacalcet
49.6
16.2
19
*
M86.1
ICD-10 Finland
Other acute osteomyelitis
49.6
16.2
19
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.2
16.1
44
78
XQ902
NOMESCO Finland
Other photography
62.5
15.9
18
*
I79.2*E11.5
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
34.9
15.9
20
6
J01CF05
ATC
flucloxacillin; systemic
6.2
15.8
43
76
A52.8
ICD-10 Finland
Late syphilis, latent
+∞
15.7
15
*
RJ410
NOMESCO Finland
NA
88.5
15.7
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
15.7
98
378
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
7.8
15.6
36
50
B01AB10
ATC
tinzaparin; parenteral
4.5
15.6
58
146
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.6
15.5
75
239
RJ420
NOMESCO Finland
NA
39.7
15.5
19
5
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
15.4
138
665
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.0
15.4
51
114
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
29.9
15.3
20
7
C07AB07
ATC
bisoprolol; oral
2.3
15.3
222
1372
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
24.5
15.3
21
9
L03.0
ICD-10 Finland
Cellulitis of finger and toe
4.7
15.2
53
125
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.4
15.0
81
280
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
11.0
15.0
28
27
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.2
14.9
47
99
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
58.9
14.9
17
*
B05DB
ATC
Hypertonic solutions
26.2
14.8
20
8
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
22.0
14.8
21
10
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
22.0
14.8
21
10
A51.0
ICD-10 Finland
Primary genital syphilis
+∞
14.7
14
*
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
+∞
14.7
14
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.6
14.6
34
48
N18.0
ICD-10 Finland
End-stage renal disease
13.2
14.6
25
20
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
14.6
95
374
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.6
14.5
52
126
C08CA01
ATC
amlodipine; oral
2.4
14.5
178
1004
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
14.4
121
556
A10BB12
ATC
glimepiride; oral
4.3
14.4
55
142
NH2AA
NOMESCO Finland
Heel X-ray examination
28.3
14.4
19
7
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
7.1
14.4
35
53
S92.3
ICD-10 Finland
Fracture of metatarsal bone
7.1
14.4
35
53
C10AA01
ATC
simvastatin; oral
2.3
14.4
202
1216
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
14.3
95
380
TAB00
NOMESCO Finland
Lumbar puncture
5.7
14.2
41
78
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.9
14.1
99
409
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
31.3
14.0
18
6
N03AX16
ATC
pregabalin; oral
2.6
14.0
126
605
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
11.0
13.9
26
25
RJ411
NOMESCO Finland
NA
24.8
13.9
19
8
H05BX01
ATC
cinacalcet; oral
55.3
13.9
16
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
13.7
62
186
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
11.5
13.7
25
23
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
35.3
13.6
17
5
ZXA00
NOMESCO Finland
Right side
2.4
13.5
143
744
H25.1
ICD-10 Finland
Senile nuclear cataract
2.6
13.4
111
504
A10BH05
ATC
linagliptin; oral
5.2
13.2
41
85
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
13.1
48
119
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.2
13.1
72
252
WX140
NOMESCO Finland
Parabulbar anesthesy
5.0
13.0
42
91
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
51.7
12.9
15
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.2
12.8
72
256
K65.0
ICD-10 Finland
Acute peritonitis
16.1
12.7
20
13
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.0
12.7
79
301
M86.8
ICD-10 Finland
Other osteomyelitis
33.2
12.7
16
5
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.7
12.6
43
99
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
12.6
12
*
F02.89*A52.1
ICD-10 Finland
Paralytic dementia
+∞
12.6
12
*
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
20.8
12.6
18
9
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
9.4
12.4
25
28
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
12.4
145
787
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.1
12.4
71
256
C03AA03
ATC
hydrochlorothiazide; oral
3.4
12.2
62
204
E0000UV
ATC
NA
2.2
12.2
172
1017
L03.9
ICD-10 Finland
Cellulitis, unspecified
9.7
12.1
24
26
SPAT1211
SPAT
Application of soft bandage
3.6
12.1
57
177
C10AA05
ATC
atorvastatin; oral
2.2
12.0
182
1106
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.7
12.0
41
95
NH3DG
NOMESCO Finland
Very extensive MRI of foot
48.1
11.9
14
*
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
15.2
11.9
19
13
NH3EA
NOMESCO Finland
Feet X-ray examination with load
10.1
11.9
23
24
A63.0
ICD-10 Finland
Anogenital (venereal) warts
31.0
11.7
15
5
162
Kela drug reimbursment
liraglutide
19.6
11.7
17
9
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
11.7
114
561
A10BK03
ATC
empagliflozin; oral
3.6
11.6
54
166
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
11.6
91
397
E66.8
ICD-10 Finland
Other obesity
4.3
11.6
43
108
M14.2*E11.6
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic arthropathy
+∞
11.5
11
*
09299
ICD-8 Finland
Early syphilis, latent, unspecified
+∞
11.5
11
*
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
11.5
11
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.9
11.5
73
281
SPAT1151
SPAT
Treatment of major wounds
12.3
11.4
20
17
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.0
11.4
46
125
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.9
11.4
37
81
I50.0
ICD-10 Finland
Congestive heart failure
3.8
11.3
48
137
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
5.3
11.2
34
69
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
5.4
11.2
33
65
A10BH01
ATC
sitagliptin; oral
3.0
11.1
68
256
C09BA02
ATC
enalapril and diuretics; systemic
3.4
11.1
56
184
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
14.4
11.1
18
13
K02.1
ICD-10 Finland
Caries of dentine
2.0
11.0
247
1745
M04AA01
ATC
allopurinol; systemic
2.8
11.0
77
315
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
44.6
11.0
13
*
NH1DG
NOMESCO Finland
Ankle and foot very extensive MRI examination with high intensity magnet
44.6
11.0
13
*
H3602, E103
ICD-10 Finland
NA
44.6
11.0
13
*
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
8.6
11.0
23
28
U14
ICPC
Kidney symptom/complaint
12.4
10.9
19
16
A10BJ02
ATC
liraglutide; parenteral
7.0
10.9
26
39
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
13.4
10.7
18
14
H26.4
ICD-10 Finland
After-cataract
3.4
10.7
53
171
N03AX12
ATC
gabapentin; oral
2.6
10.7
83
360
WX110
NOMESCO Finland
Local anesthesy
2.1
10.6
291
2214
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.1
10.5
28
49
TNF34
NOMESCO Finland
Major custom moulded orthopaedic cast, hip or thigh
+∞
10.5
10
*
M146, E109
ICD-10 Finland
NA
+∞
10.5
10
*
A52.3
ICD-10 Finland
Neurosyphilis, unspecified
+∞
10.5
10
*
RJ523
NOMESCO Finland
NA
+∞
10.5
10
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
16.6
10.4
16
10
ZXA05
NOMESCO Finland
Left side
2.2
10.4
122
655
L16
ICPC
Ankle symptom/complaint
3.1
10.4
59
211
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
19.4
10.3
15
8
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
10.3
186
1197
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
10.3
54
183
J01CE08
ATC
benzathine benzylpenicillin; parenteral
13.6
10.2
17
13
C09AA05
ATC
ramipril; oral
2.2
10.2
119
633
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.3
10.2
38
96
R11
ICD-10 Finland
Nausea and vomiting
3.6
10.0
46
140
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.1
9.9
134
762
A06AD11
ATC
lactulose; oral
2.8
9.9
67
267
TQW80
NOMESCO Finland
Local dermatologic skincare
6.8
9.9
24
37
XF600
NOMESCO Finland
Bloodpressure measurement
3.6
9.9
44
131
V03AE03
ATC
lanthanum carbonate; oral
26.7
9.9
13
5
N02AX02
ATC
tramadol; systemic, rectal
2.0
9.8
197
1310
E000001
ATC
NA
2.4
9.8
95
462
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
4.3
9.8
36
90
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.4
9.8
48
154
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.6
9.8
33
76
R4110
NOMESCO Finland
Physiotherapy
2.1
9.8
125
694
A10BX04
ATC
[U] exenatide; parenteral
13.8
9.7
16
12
RJ120
NOMESCO Finland
NA
56.3
9.7
11
*
RJ512
NOMESCO Finland
NA
56.3
9.7
11
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.0
9.7
26
46
A28
ICPC
Limited function/disability NOS
2.6
9.6
75
325
N02AA05
ATC
oxycodone; systemic
2.6
9.6
77
337
A41.9
ICD-10 Finland
Sepsis, unspecified
4.8
9.6
31
68
N06AX21
ATC
duloxetine; oral
2.9
9.6
60
229
TNX39
NOMESCO Finland
Other orthopedic bandage, unspecified region
6.9
9.6
23
35
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.5
9.5
33
78
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
2.0
9.5
182
1186
RJ126
NOMESCO Finland
NA
102.2
9.5
10
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
30.8
9.4
12
*
AA1AD
NOMESCO Finland
CT of head and brain
2.2
9.4
112
599
M10.9
ICD-10 Finland
Gout, unspecified
3.3
9.4
48
159
M146, E119
ICD-10 Finland
NA
+∞
9.4
9
*
NHS20
NOMESCO Finland
Incision and debridement of infection of bone of ankle or foot
+∞
9.4
9
*
E14.4
ICD-10 Finland
Unspecified diabetes mellitus, with neurological complications
+∞
9.4
9
*
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
9.4
9
*
QDG00
NOMESCO Finland
Debridement of bedsore of lower limb
+∞
9.4
9
*
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
6.7
9.4
23
36
J04AB02
ATC
rifampicin; systemic
11.0
9.4
17
16
E66.9
ICD-10 Finland
Obesity, unspecified
6.0
9.4
25
44
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.2
9.3
102
526
SPAT1254
SPAT
Administration of medicine
2.6
9.3
71
305
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.1
9.2
121
675
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.0
9.1
53
193
ZX114
NOMESCO Finland
Intramuscular
16.0
9.1
14
9
RJ521
NOMESCO Finland
NA
37.6
9.1
11
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
9.0
42
130
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
9.0
46
153
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
9.0
62
250
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
24.6
9.0
12
5
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
9.0
217
1529
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
8.9
59
232
R5599
NOMESCO Finland
Other rehabilitation service
5.4
8.9
26
51
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
8.9
40
120
WX882
NOMESCO Finland
High dependency care
5.6
8.9
25
47
S76
ICPC
Skin infection other
4.1
8.9
34
89
B01AC04
ATC
clopidogrel; oral
2.4
8.9
78
361
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.0
8.8
130
760
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
7.9
8.7
19
25
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
6.4
8.7
22
36
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
51.1
8.7
10
*
H25.8
ICD-10 Finland
Other senile cataract
2.8
8.7
55
212
RJ421
NOMESCO Finland
NA
16.7
8.6
13
8
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
16.7
8.6
13
8
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
28.2
8.5
11
*
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
28.2
8.5
11
*
TK820
NOMESCO Finland
Peritoneal dialysis
20.5
8.5
12
6
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
20.5
8.5
12
6
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
8.5
71
319
H02AB04
ATC
methylprednisolone; systemic
2.5
8.5
71
320
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.1
8.5
32
83
RJ129
NOMESCO Finland
NA
91.8
8.4
9
*
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
6.4
8.4
21
34
ZX120
NOMESCO Finland
Intravenous
2.9
8.4
51
189
E14.6
ICD-10 Finland
Unspecified diabetes mellitus, with other specified complications
+∞
8.4
8
*
M146, E117
ICD-10 Finland
NA
+∞
8.4
8
*
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
+∞
8.4
8
*
A10AA03
ATC
NA
11.1
8.4
15
14
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.7
8.3
61
253
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
8.3
77
365
R50.9
ICD-10 Finland
Fever, unspecified
2.5
8.2
67
297
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.7
8.2
35
101
L29
ICPC
Musculoskeletal sympt/complt other
3.1
8.2
46
162
C03DA01
ATC
spironolactone; oral
2.7
8.2
58
238
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.5
8.2
69
312
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
7.1
8.2
19
28
TKC20
NOMESCO Finland
Catheterisation of bladder
3.4
8.2
38
118
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
12.0
8.1
14
12
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
5.5
8.1
23
44
J01CF02
ATC
cloxacillin; systemic
5.5
8.1
23
44
WX892
NOMESCO Finland
Monitored bed care
3.1
8.1
43
147
321
Kela drug reimbursment
Paricalcitol and cinacalcet
34.1
8.1
10
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
34.1
8.1
10
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
8.0
47
172
E000003
ATC
NA
3.8
8.0
33
93
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
6.8
8.0
19
29
NG4AA
NOMESCO Finland
Lower leg X-ray examination
5.6
7.9
22
41
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.4
7.9
69
316
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
7.8
31
84
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
7.7
7.7
17
23
RJ511
NOMESCO Finland
NA
45.8
7.7
9
*
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
45.8
7.7
9
*
ZXA10
NOMESCO Finland
Bilateral
2.2
7.7
84
431
J01DA09
ATC
[U] cefadroxil; inhalant, oral
2.0
7.7
117
687
WX722
NOMESCO Finland
PEEP
3.8
7.6
31
86
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
7.6
44
159
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.2
7.6
85
436
N02BE01
ATC
paracetamol; systemic, rectal
2.1
7.6
347
2961
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
7.6
57
241
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.1
7.5
28
72
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.3
7.5
36
115
SPAT1263
SPAT
Sampling
1.8
7.5
172
1167
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
7.5
94
512
NHS99
NOMESCO Finland
Other operation for infection of tendon, joint or bone of ankle or foot
81.5
7.4
8
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
81.5
7.4
8
*
M86.2
ICD-10 Finland
Subacute osteomyelitis
81.5
7.4
8
*
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
81.5
7.4
8
*
N05CF01
ATC
zopiclone; oral
1.9
7.4
141
897
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
7.4
59
257
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
13.7
7.4
12
9
A10BX01
ATC
guar gum; systemic
5.1
7.4
22
45
C02CA01
ATC
prazosin; oral
8.6
7.4
15
18
SPAT1231
SPAT
Assessment of adjustments needed in living environment
7.0
7.4
17
25
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
7.3
7
*
A52.2
ICD-10 Finland
Asymptomatic neurosyphilis
+∞
7.3
7
*
NH3BM
NOMESCO Finland
MRI of foot (more than 1.5 T)
+∞
7.3
7
*
M14.2
ICD-10 Finland
Diabetic arthropathy
+∞
7.3
7
*
RJ122
NOMESCO Finland
NA
+∞
7.3
7
*
M146, E114
ICD-10 Finland
NA
+∞
7.3
7
*
M77.4
ICD-10 Finland
Metatarsalgia
3.6
7.3
31
90
A04
ICPC
Weakness/tiredness general
2.6
7.3
53
222
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.8
7.2
46
178
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.8
7.2
231
1732
M86.4
ICD-10 Finland
Chronic osteomyelitis with draining sinus
30.6
7.2
9
*
RJ210
NOMESCO Finland
NA
30.6
7.2
9
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
20.4
7.2
10
5
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
20.4
7.2
10
5
N05BA01
ATC
diazepam; systemic, rectal
2.4
7.2
63
291
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.7
7.2
30
86
K07
ICPC
Swollen ankles/oedema
4.1
7.1
26
66
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
7.2
7.1
16
23
B01AB04
ATC
dalteparin; parenteral
3.5
7.1
32
98
H03AA01
ATC
levothyroxine sodium; systemic
2.1
7.0
87
468
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
7.0
162
1093
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
6.5
7.0
17
27
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
6.0
7.0
18
31
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
7.0
40
144
C07AG02
ATC
carvedilol; oral
3.2
7.0
35
116
A02BC02
ATC
pantoprazole; systemic
1.8
6.9
261
2045
G47.3
ICD-10 Finland
Sleep apnoea
2.0
6.9
104
606
A01
ICPC
Pain general/multiple sites
3.0
6.9
39
138
T82
ICPC
Obesity
4.3
6.9
24
58
S19
ICPC
Skin injury other
4.3
6.9
24
58
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
8.5
6.9
14
17
SPAT1240
SPAT
Therapeutic discussion
2.7
6.8
45
178
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
11.2
6.8
12
11
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
4.0
6.8
26
69
358
Kela drug reimbursment
liraglutide
40.7
6.8
8
*
PB1AC
NOMESCO Finland
Angiography of upper extremity with X-ray
40.7
6.8
8
*
A10BG02
ATC
rosiglitazone; oral
7.4
6.8
15
21
Z89.5
ICD-10 Finland
Acquired absence of leg at or below knee
22.9
6.7
9
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
22.9
6.7
9
*
E10.01
ICD-10 Finland
Insulin-dependent diabetes diabetic coma with hyperglycemia
22.9
6.7
9
*
WX214
NOMESCO Finland
Plexus blockade at the ankle
22.9
6.7
9
*
A10BH02
ATC
vildagliptin; oral
5.7
6.7
18
33
C08CA13
ATC
lercanidipine; oral
2.3
6.7
64
307
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
12.5
6.6
11
9
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
12.5
6.6
11
9
S92.0
ICD-10 Finland
Fracture of calcaneus
12.5
6.6
11
9
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
4.1
6.6
24
61
S21
ICPC
Skin texture symptom/complaint
2.4
6.6
57
261
K59.1
ICD-10 Finland
Functional diarrhoea
3.6
6.6
28
82
-56
ICPC
Dressing/pressure/compress/tamponade
6.4
6.5
16
26
EBA00
NOMESCO Finland
Extraction of tooth
1.8
6.5
144
956
R53
ICD-10 Finland
Malaise and fatigue
2.0
6.4
83
454
2505B
ICD-9 Finland
Diabetes mellitus, Diabetes with ophthalmic manifestations[NEUROPATHIA DIABETICA,TYYPPI I]
70.9
6.4
7
*
K65.8
ICD-10 Finland
Other peritonitis
70.9
6.4
7
*
NH1CF
NOMESCO Finland
Ankle and foot extensive MRI examination with median intensity magnet
70.9
6.4
7
*
RJ513
NOMESCO Finland
NA
70.9
6.4
7
*
M86.0
ICD-10 Finland
Acute haematogenous osteomyelitis
70.9
6.4
7
*
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
6.4
41
158
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
6.4
48
204
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
6.4
153
1038
L14
ICPC
Leg/thigh symptom/complaint
3.0
6.4
36
127
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
6.4
277
2239
S17
ICPC
Abrasion/scratch/blister
5.7
6.4
17
31
ZZR00
NOMESCO Finland
Flap of skin
5.7
6.4
17
31
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
11.3
6.3
11
10
R4120
NOMESCO Finland
Occupational therapy
2.8
6.3
38
143
A12BA01
ATC
potassium chloride; oral
3.9
6.3
24
64
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
18.3
6.3
9
5
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
7.2
6.3
14
20
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
7.2
6.3
14
20
RJ211
NOMESCO Finland
NA
+∞
6.3
6
*
171
Kela drug reimbursment
Degludekinsuliini
27.1
6.2
8
*
QD6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in foot
27.1
6.2
8
*
H3603, E107
ICD-10 Finland
NA
27.1
6.2
8
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
6.2
155
1065
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.6
6.2
44
183
M65.3
ICD-10 Finland
Trigger finger
3.6
6.1
26
76
R5120
NOMESCO Finland
Preparation of an aid
4.5
6.1
20
46
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.4
6.1
49
216
A10BK01
ATC
dapagliflozin; oral
3.1
6.1
32
110
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.3
6.1
21
51
SPAT1310
SPAT
Counselling related to known health issue
1.8
6.1
130
847
ACC51
NOMESCO Finland
Release of median nerve
2.7
6.1
39
151
B03XA01
ATC
erythropoietin; parenteral
10.2
6.1
11
11
L85.3
ICD-10 Finland
Xerosis cutis
10.2
6.1
11
11
SPAT1298
SPAT
Other function in accordance with nutritional therapy nomenclature
10.2
6.1
11
11
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
4.7
6.1
19
42
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
6.0
39
152
S10
ICPC
Boil/carbuncle
3.3
6.0
28
88
H16.0
ICD-10 Finland
Corneal ulcer
3.3
6.0
28
88

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
204
504
6.47
84.89
18.3
6.0
1.1
1.0
mmol/l
3.37
194
469
75
53
16.71
84.61
7.8
1.9
7.6
—
titre
—
32
0
206
571
5.71
74.00
5.4
2.1
—
—
—
0
0
58
41
16.04
65.01
6.0
2.0
4902.0
—
titre
—
40
0
146
331
5.99
64.76
21.1
7.6
14.0
9.7
mmol/l
8.16
137
313
278
1121
4.73
59.92
6.5
3.2
370.0
327.4
mg/l
0.08
236
748
286
1191
4.69
58.71
6.4
3.1
6.2
8.1
mmol/l
14.58
259
1004
167
462
5.10
58.30
4.1
1.6
—
—
—
0
0
122
264
5.92
56.31
9.1
4.0
154.3
86.3
ng/l
5.37
110
236
281
1186
4.51
55.86
8.1
3.9
43.4
9.3
mg/mmol
5.23
232
772
316
1589
4.14
46.00
11.1
5.0
33.8
35.7
g/l
6.60
299
1502
160
508
4.29
45.45
6.6
2.3
18.8
23.5
%
5.55
140
444
165
536
4.24
45.42
6.5
2.3
2.1
2.3
g/l
4.71
156
497
173
584
4.14
45.11
6.4
2.3
9.8
13.4
umol/l
12.19
165
542
244
1044
3.84
44.95
9.3
4.5
—
—
—
0
0
74
122
7.03
44.48
6.9
3.5
0.4
0.3
g/l
0.62
61
52
268
1226
3.83
44.48
9.0
5.7
—
—
—
0
0
132
404
4.18
38.77
3.8
1.6
—
—
—
0
0
65
111
6.65
37.59
5.0
3.1
2.1
1.5
mg/l
4.02
60
102
201
868
3.33
34.44
3.3
2.0
3.4
3.1
mg/l
0.93
176
767
271
1419
3.21
33.03
3.9
2.2
72.3
75.9
nmol/l
1.28
242
1277
75
166
5.20
32.84
2.0
1.9
1.6
1.5
g/l
0.15
68
143
300
1701
3.19
31.16
10.0
5.9
0.7
0.7
%
0.38
278
1600
294
1650
3.16
31.06
16.1
6.3
1.2
1.2
mmol/l
0.01
273
1507
321
1911
3.24
30.24
9.8
6.2
0.2
0.2
e9/l
2.02
275
1706
156
622
3.28
29.83
4.5
3.3
0.8
0.8
mmol/l
0.85
139
593
302
1748
3.11
29.68
9.9
5.9
2.9
2.9
%
0.07
280
1642
268
1455
3.01
29.55
2.6
1.9
98.5
93.9
pmol/l
0.66
155
779
352
2233
3.44
29.30
11.2
5.0
8.6
6.7
mmol/l
19.85
337
2093
213
1025
3.00
29.21
4.3
2.6
4331.8
8893.9
umol/l
0.74
190
891
313
1860
3.13
29.12
9.4
5.9
0.0
0.0
e9/l
1.64
270
1623
102
314
3.89
29.06
4.6
2.5
71.2
71.4
e9/l
0.02
81
242
302
1761
3.07
29.04
10.4
6.1
8.5
8.8
%
0.86
281
1662
311
1850
3.09
28.71
9.4
5.9
0.6
0.6
e9/l
2.20
269
1611
304
1792
3.04
28.41
10.2
6.0
25.0
27.2
%
2.81
279
1684
313
1895
3.03
27.48
9.3
5.9
1.8
1.9
e9/l
0.92
274
1686
104
337
3.69
27.38
10.6
3.8
5.9
5.8
kpa
0.56
99
326
103
332
3.71
27.33
10.6
3.8
0.9
2.1
mmol/l
1.58
88
270
98
308
3.77
26.97
12.7
9.2
—
—
—
0
0
298
1769
2.94
26.91
9.8
5.8
60.5
57.6
%
3.99
274
1669
303
1819
2.94
26.71
21.6
7.0
1.2
1.2
mmol/l
1.04
257
1546
322
2006
3.01
26.32
8.0
6.6
11.0
11.6
umol/l
0.18
309
1913
120
440
3.34
25.95
4.3
2.6
1.9
1.8
%
0.30
109
406
83
240
4.00
25.66
7.9
3.2
7.4
7.4
ph
0.09
19
33
84
245
3.97
25.66
8.0
3.1
5.1
5.1
kpa
0.27
78
228
241
1305
2.77
25.55
6.2
3.8
78.2
112.9
e6/l
0.39
178
939
95
303
3.69
25.49
3.4
2.9
66.0
66.9
g/l
0.54
88
275
333
2152
2.97
24.68
12.0
9.9
4.8
4.1
e9/l
3.93
282
1899
29
32
9.60
24.09
2.5
2.7
26.6
37.1
%
—
5
7
84
259
3.74
23.60
3.1
1.5
—
—
—
0
0
193
965
2.72
23.48
4.2
2.9
—
—
—
0
0
98
337
3.42
23.30
4.4
2.5
32.5
179.9
u/l
0.52
83
285
208
1085
2.67
23.18
11.3
4.4
7.4
7.4
ph
2.04
46
208
81
247
3.77
23.10
2.1
2.5
—
—
—
0
0
198
1010
2.68
23.06
5.2
3.0
—
—
—
0
0
166
775
2.78
23.02
4.2
2.6
7.9
5.2
e6/l
0.53
154
682
149
659
2.86
22.89
2.2
1.7
1201.5
1204.0
nmol/l
0.01
115
516
187
930
2.70
22.88
9.2
7.0
—
—
—
0
0
213
1138
2.62
22.42
5.3
3.2
44.5
114.2
e6/l
0.61
170
873
195
1039
2.52
20.14
2.4
1.7
1.6
1.4
mmol/l
0.78
174
885
152
722
2.65
19.93
4.5
2.9
472.6
575.5
mosm/kgh2o
8.24
136
617
179
923
2.54
19.76
6.7
3.9
93.1
90.3
%
0.78
174
904
69
211
3.67
19.47
2.9
1.6
—
—
—
0
0
57
153
4.11
19.33
2.5
2.2
4.9
3.7
ug/l
0.18
51
141
192
1039
2.45
18.92
5.4
3.1
0.6
0.5
e6/l
0.20
154
772
17
12
14.67
18.57
5.2
4.9
—
—
—
0
0
388
2913
3.10
18.48
14.7
7.9
96.2
79.3
u/l
3.16
375
2742
95
369
2.98
18.11
2.5
2.3
0.2
0.2
g/l
0.87
84
339
110
466
2.79
17.85
2.8
1.6
—
—
—
0
0
248
1530
2.34
17.83
13.2
8.4
1.2
1.2
inr
0.12
72
442
349
2509
2.61
17.61
8.0
4.1
—
—
—
0
0
43
100
4.64
17.50
4.6
2.4
23.6
24.2
mmol/l
0.32
38
88
241
1498
2.28
16.65
6.4
2.6
165.5
152.9
ug/l
0.37
229
1393
37
79
5.00
16.65
5.3
2.6
16.1
16.1
%
0.02
25
37
18
17
10.98
16.53
1.8
1.8
—
—
—
0
0
41
98
4.49
16.11
9.3
1.9
1.3
0.9
nmol/l
1.15
30
87
46
121
4.11
15.98
3.5
2.5
251.6
100.3
ug/min
0.84
28
67
160
849
2.35
15.95
1.9
1.5
22.2
20.4
nmol/l
0.78
147
731
121
566
2.54
15.93
3.0
1.7
—
—
—
0
0
199
1160
2.26
15.86
5.2
3.6
2.3
2.3
mmol/l
0.06
171
1032
251
1635
2.17
14.87
22.0
9.6
0.0
0.0
e9/l
0.18
202
1347
121
583
2.46
14.84
2.9
2.0
30.4
29.6
s
0.60
115
568
75
285
2.95
14.71
7.5
2.8
5.2
4.5
kpa
1.68
70
275
45
125
3.88
14.49
2.6
3.8
92.3
103.9
mg/l
0.08
37
98
45
125
3.88
14.49
2.6
3.8
60.0
37.2
mg/l
1.29
37
100
45
125
3.88
14.49
2.6
3.7
1.2
2.3
ratio
—
5
15
31
65
5.04
14.22
1.1
1.1
243.1
23.0
iu/ml
—
7
11
40
104
4.12
14.09
1.8
1.5
221.5
271.3
ug/g
0.85
29
58
54
173
3.40
14.08
8.6
3.2
—
—
—
0
0
98
439
2.57
13.96
9.9
8.5
1.5
1.2
mmol/l
0.30
84
355
122
605
2.38
13.95
3.9
2.9
4.0
1.7
e6/l
1.20
69
327
145
776
2.27
13.87
1.7
1.2
1.8
1.3
u/ml
0.26
37
227
157
884
2.18
13.13
3.9
2.3
—
—
—
0
0
101
473
2.45
13.03
1.8
1.4
—
—
—
0
0
191
1165
2.09
12.93
4.4
2.4
—
—
—
0
0
178
1060
2.11
12.82
4.3
3.1
4079.4
1249.6
ng/l
5.60
151
895
35
89
4.17
12.69
10.6
3.4
2.8
2.6
mmol/l
0.19
27
60
35
89
4.17
12.69
10.7
3.4
5.2
5.0
kpa
0.51
35
89
35
89
4.17
12.69
10.7
3.4
8.2
8.6
kpa
0.95
35
89
148
825
2.17
12.62
4.4
3.4
—
—
—
0
0
33
81
4.31
12.52
2.5
1.5
—
—
—
0
0
31
73
4.48
12.39
1.5
1.2
324.3
275.2
u/ml
0.28
19
43
30
69
4.58
12.34
4.8
2.5
—
—
—
0
0
33
82
4.26
12.33
10.2
3.3
—
—
—
0
0
21
35
6.24
12.23
1.5
1.1
—
—
—
0
0
35
93
3.99
11.97
2.4
4.3
—
—
—
0
0
354
2760
2.22
11.79
6.4
4.0
21.0
11.8
mm/h
12.95
332
2557
184
1139
2.02
11.70
2.4
2.1
164.1
266.2
u/l
0.88
176
1085
30
73
4.33
11.51
2.4
1.5
85.7
101.9
u/ml
0.76
11
14
132
733
2.12
11.18
2.1
1.7
454.1
24840180.4
pmol/l
0.69
107
624
93
449
2.34
11.08
3.5
2.9
9.5
9.1
umol/l
0.05
84
398
29
72
4.23
10.84
8.9
3.2
—
—
—
0
0
95
475
2.26
10.39
27.3
20.1
1.6
1.3
inr
—
10
63
35
104
3.56
10.21
1.4
1.2
—
—
—
0
0
53
203
2.82
10.16
8.0
11.0
24.2
24.6
mmol/l
0.30
44
191
76
355
2.37
9.70
2.1
2.0
392.3
361.6
nmol/l
0.68
69
328
20
40
5.18
9.65
1.5
2.9
—
—
—
0
0
54
215
2.71
9.61
12.5
10.5
—
—
—
0
0
241
1711
1.86
9.61
6.6
4.0
—
—
—
0
0
96
504
2.14
9.23
1.4
1.3
—
—
—
0
0
19
38
5.17
9.17
1.7
1.4
6843.2
1412.9
e6/l
0.40
11
23
33
102
3.41
9.08
4.2
3.6
—
—
—
0
0
15
24
6.43
9.04
2.2
2.8
507.2
528.8
min
—
9
14
18
35
5.31
8.95
1.6
1.4
64246.4
25267.1
e6/l
0.49
11
18
12
5
24.56
8.95
9.7
6.2
9.1
8.1
mmol/l
—
12
5
19
39
5.04
8.91
1.2
1.2
—
—
—
0
0
58
249
2.52
8.87
8.8
5.3
—
—
—
0
0
247
1797
1.81
8.82
5.5
3.5
0.0
0.0
estimate
0.00
49
329
23
56
4.27
8.82
1.1
1.1
—
—
—
0
0
121
708
1.96
8.60
1.8
1.4
2.9
2.6
g/l
0.84
68
450
27
76
3.71
8.53
4.2
3.1
—
—
—
0
0
9
402
0.21
8.23
1.3
1.4
—
—
—
0
0
19
42
4.68
8.19
2.4
2.4
—
—
—
0
0
27
79
3.57
8.07
1.1
1.7
—
—
—
0
0
23
60
3.98
8.07
2.7
3.3
4.9
4.5
e9/l
0.22
23
60
244
1799
1.76
8.06
7.6
4.8
0.0
0.0
estimate
0.00
51
331
11
14
8.02
8.02
1.0
1.1
—
—
—
0
0
66
316
2.27
7.91
3.4
2.4
4.5
8.4
ug/l
2.74
55
287
178
1210
1.77
7.72
7.3
2.7
53.5
58.5
u/l
0.56
164
1135
24
67
3.72
7.68
5.4
1.9
63.4
64.7
%
0.08
24
67
63
300
2.27
7.64
2.2
2.4
10.9
10.7
g/l
0.12
54
275
245
1826
1.73
7.64
5.7
3.5
0.0
0.0
estimate
0.00
39
315
11
15
7.49
7.58
1.0
1.0
—
—
—
0
0
23
63
3.79
7.56
3.3
3.9
62.8
57.1
%
1.19
23
63
117
705
1.88
7.51
4.9
3.8
201.4
365.8
ng/l
0.57
100
553
407
3548
2.26
7.51
14.6
5.8
52.3
40.0
mmol/mol
36.26
389
3329
18
41
4.53
7.49
1.6
1.6
—
—
—
0
0
162
1080
1.77
7.47
5.4
3.9
—
—
—
0
0
17
37
4.73
7.46
1.9
1.4
—
—
—
0
0
29
95
3.19
7.29
1.5
1.6
14604.1
18705.0
e6/l
0.21
18
73
90
501
1.99
7.29
1.4
1.3
290.0
387.7
titre
0.52
16
114
56
265
2.27
6.89
1.3
1.2
—
—
—
0
0
419
3743
2.31
6.50
43.9
14.3
25.9
24.7
mg/l
0.36
375
2962
67
349
2.08
6.48
14.1
3.9
—
—
—
0
0
11
18
6.24
6.46
4.7
2.3
—
—
—
0
0
21
61
3.56
6.36
2.1
3.3
1.8
1.1
%
0.32
16
51
22
66
3.45
6.35
1.1
1.1
—
—
—
0
0
123
790
1.76
6.29
1.8
1.7
1.2
1.3
mg/l
0.24
99
623
15
34
4.53
6.28
2.2
2.5
1131.7
606.1
ml
—
9
18
14
30
4.78
6.25
4.6
2.5
—
—
—
0
0
202
1484
1.64
6.24
6.5
3.7
64.5
47.3
ng/l
0.72
168
1045
51
244
2.23
6.11
1.6
1.7
1.1
1.7
g/l
1.20
44
226
59
303
2.09
5.92
4.2
4.8
0.1
0.1
%
0.30
26
96
57
290
2.10
5.86
3.5
4.7
1.1
0.4
%
0.49
22
80
22
70
3.25
5.82
1.2
1.1
—
—
—
0
0
35
145
2.53
5.77
1.5
1.8
—
—
—
0
0
12
25
4.90
5.52
1.2
1.6
—
—
—
0
0
381
3342
1.81
5.48
6.2
4.3
1.9
2.3
mu/l
0.43
349
3058
11
22
5.10
5.28
1.2
1.3
—
—
—
0
0
17
49
3.56
5.22
2.2
3.3
—
—
—
0
0
18
54
3.43
5.21
1.2
1.5
—
—
—
0
0
60
327
1.96
5.12
4.1
4.6
1.2
0.8
%
0.26
27
109
41
194
2.22
5.06
7.3
2.5
1.0
1.3
%
1.19
41
194
9
9
10.17
5.04
1.6
1.8
—
—
—
0
0
20
67
3.08
4.89
1.8
1.1
—
—
—
0
0
98
634
1.69
4.77
2.8
3.3
2.5
2.4
mmol/l
1.08
74
560
19
63
3.10
4.72
1.5
1.6
—
—
—
0
0
8
8
10.15
4.53
2.3
1.3
—
—
—
0
0
317
2705
1.55
4.49
4.9
3.6
14.9
14.8
pmol/l
0.42
289
2458
422
3884
2.02
4.39
49.2
16.4
138.6
139.7
mmol/l
14.02
413
3794
11
26
4.31
4.38
1.6
1.0
—
—
—
0
0
23
89
2.67
4.37
1.2
1.4
371.6
247.4
miu/ml
—
5
46
7
6
11.82
4.29
2.9
1.5
—
—
—
0
0
17
56
3.11
4.28
3.5
3.1
0.7
0.7
nmol/l
0.05
12
48
52
288
1.91
4.24
4.4
4.9
0.0
0.1
%
0.66
24
85
12
32
3.82
4.11
1.2
1.2
—
—
—
0
0
422
3899
1.97
4.10
50.3
16.6
4.1
4.0
mmol/l
10.18
412
3806
8
10
8.12
4.07
1.3
1.7
2.8
1.7
umol/l
—
8
10
41
213
2.02
4.01
1.6
1.2
—
—
—
0
0
30
141
2.21
3.80
13.3
5.2
—
—
—
0
0
107
1465
0.65
3.73
4.6
2.9
—
—
—
0
0
15
50
3.07
3.72
1.5
1.2
—
—
—
0
0
23
97
2.44
3.71
1.6
1.2
—
—
—
0
0
8
12
6.76
3.68
2.4
1.6
—
—
—
0
0
7
9
7.88
3.57
1.1
1.0
—
—
—
0
0
8
13
6.24
3.51
3.6
3.2
—
—
—
0
0
50
291
1.81
3.51
8.1
3.7
—
—
—
0
0
50
291
1.81
3.51
3.4
3.0
396.4
177.3
ng/l
1.73
42
258
19
75
2.60
3.51
1.3
1.6
—
—
—
0
0
16
58
2.82
3.45
1.3
1.5
—
—
—
0
0
9
21
4.35
3.01
1.0
1.1
—
—
—
0
0
18
75
2.46
3.00
1.7
1.9
—
—
—
0
0
35
192
1.89
2.98
3.1
3.3
4.0
4.6
pmol/l
3.73
28
170
379
3471
1.52
2.95
37.3
15.1
38.2
40.6
%
5.84
255
2568
8
17
4.77
2.93
2.8
1.6
—
—
—
0
0
19
83
2.34
2.88
1.1
1.3
—
—
—
0
0
21
417
0.48
2.84
1.7
1.6
—
—
—
0
0
13
48
2.76
2.74
1.8
1.7
31.1
33.5
pg
1.37
13
48
25
126
2.04
2.71
1.9
1.6
—
—
—
0
0
8
20
4.05
2.58
3.4
3.5
33.0
19.3
mu/l
—
8
20
345
3131
1.40
2.57
46.1
17.7
14.1
13.7
%
5.05
339
3075
65
442
1.55
2.57
1.3
1.3
—
—
—
0
0
13
50
2.65
2.55
1.5
1.2
—
—
—
0
0
6
11
5.51
2.55
1.2
1.0
1645.7
1214.5
miu/ml
—
6
11
9
26
3.51
2.49
1.0
1.3
—
—
—
0
0
14
57
2.50
2.47
1.7
3.3
—
—
—
0
0
46
291
1.65
2.45
8.5
3.2
—
—
—
0
0
410
3856
1.57
2.43
7.7
5.0
2.2
2.8
mmol/l
28.02
386
3579
10
34
2.98
2.42
1.8
1.4
—
—
—
0
0
10
34
2.98
2.42
2.5
1.1
—
—
—
0
0
402
3765
1.53
2.42
7.1
4.4
1.3
1.4
mmol/l
7.66
374
3492
404
3789
1.54
2.40
7.1
4.5
4.0
4.6
mmol/l
24.70
376
3531
74
1008
0.68
2.35
2.7
2.8
0.7
0.7
ug/l
0.51
49
636
5
154
0.32
2.32
2.0
1.8
—
—
—
0
0
10
35
2.90
2.32
1.1
1.4
—
—
—
0
0
8
23
3.52
2.28
2.1
1.5
2.1
0.9
u/field
—
8
16
6
13
4.66
2.28
1.2
1.5
32.8
28.0
umol/l
—
6
13
390
3645
1.45
2.22
6.0
4.0
1.5
1.3
mmol/l
3.93
357
3375
5
9
5.60
2.22
1.0
1.4
—
—
—
0
0
10
36
2.82
2.21
1.0
1.1
—
—
—
0
0
12
49
2.49
2.12
1.0
1.8
—
—
—
0
0
10
37
2.74
2.11
1.1
1.2
—
—
—
0
0
5
10
5.04
2.07
1.6
2.4
—
—
—
0
0
35
216
1.67
2.07
3.0
3.0
0.7
0.1
e6/l
0.77
35
211
7
20
3.54
2.06
1.0
1.1
—
—
—
0
0
58
405
1.49
2.05
2.8
4.8
21.0
44.1
ug/l
0.51
47
337
6
15
4.04
2.04
1.2
1.0
248.5
267.8
iu/ml
—
6
15
21
111
1.93
2.04
1.8
1.1
—
—
—
0
0
37
233
1.64
2.03
4.0
2.4
—
—
—
0
0
8
26
3.11
2.02
1.5
4.0
—
—
—
0
0
12
252
0.46
1.94
1.9
1.4
—
—
—
0
0
26
153
1.74
1.84
1.3
1.2
—
—
—
0
0
9
35
2.60
1.81
5.7
3.7
—
—
—
0
0
424
4061
1.55
1.80
21.0
10.5
26.2
28.2
u/l
1.06
414
3940
8
29
2.79
1.80
1.8
1.2
—
—
—
0
0
422
4039
1.53
1.78
45.2
16.8
115.8
79.5
umol/l
10.85
422
4039
25
147
1.74
1.78
2.8
2.7
—
—
—
0
0
76
577
1.38
1.73
1.3
1.3
3.1
12.6
u/ml
2.13
19
225
5
13
3.88
1.72
1.4
1.2
—
—
—
0
0
32
204
1.61
1.70
1.1
1.2
73.1
126.7
iu/ml
1.24
11
74
63
467
1.40
1.65
1.3
1.3
—
—
—
0
0
7
25
2.83
1.65
6.7
4.2
—
—
—
0
0
47
334
1.45
1.55
1.5
1.4
—
—
—
0
0
27
173
1.60
1.43
2.4
2.2
—
—
—
0
0
293
2703
1.23
1.34
5.5
3.9
—
—
—
0
0
7
148
0.46
1.34
15.7
10.2
—
—
—
0
0
33
226
1.50
1.33
1.5
1.3
—
—
—
0
0
10
48
2.11
1.28
1.4
1.6
—
—
—
0
0
10
48
2.11
1.28
1.4
1.6
—
—
—
0
0
10
48
2.11
1.28
1.4
1.6
—
—
—
0
0
10
48
2.11
1.28
1.4
1.6
—
—
—
0
0
28
406
0.67
1.25
1.4
1.4
—
—
—
0
0
411
3956
1.36
1.25
40.2
13.2
—
—
—
0
0
6
25
2.42
1.24
1.5
1.2
—
—
—
0
0
164
1439
1.22
1.21
2.2
2.1
—
—
—
0
0
36
257
1.43
1.20
2.4
2.5
—
16.4
—
0
12
75
604
1.29
1.17
1.3
1.3
40.5
36.5
iu/ml
0.08
22
188
5
20
2.52
1.15
1.6
1.6
—
—
—
0
0
5
20
2.52
1.15
1.6
1.8
—
—
—
0
0
14
80
1.77
1.14
1.6
1.7
—
—
—
0
0
113
960
1.23
1.13
7.5
3.7
0.0
0.0
estimate
0.50
41
316
35
254
1.41
1.08
4.6
2.5
5.6
4.2
e9/l
0.97
18
202
53
414
1.32
1.05
1.7
2.3
109.5
133.4
ug/g
0.47
44
346
32
231
1.41
1.02
1.3
1.3
—
44.2
—
0
14
9
47
1.93
1.02
1.0
1.1
—
—
—
0
0
7
35
2.02
1.00
1.6
1.1
—
—
—
0
0
0
30
0.00
0.97
0.0
1.3
—
—
—
0
0
29
211
1.40
0.91
1.4
1.2
844.0
273.2
u/ml
0.48
23
189
6
30
2.01
0.87
1.2
1.3
—
—
—
0
0
12
72
1.68
0.86
1.2
1.9
—
—
—
0
0
6
112
0.53
0.84
1.2
1.1
—
—
—
0
0
8
46
1.75
0.83
1.3
1.3
—
—
—
0
0
15
97
1.56
0.82
1.1
1.4
—
—
—
0
0
6
32
1.89
0.82
2.5
1.9
11.8
12.2
%
—
6
32
5
24
2.09
0.74
5.6
2.0
—
—
—
0
0
25
185
1.37
0.73
2.9
4.0
—
—
—
0
0
6
107
0.56
0.73
6.5
5.0
—
—
—
0
0
5
25
2.01
0.73
2.0
4.1
—
—
—
0
0
7
41
1.72
0.70
1.1
1.2
—
—
nmol/l
—
0
0
429
4204
1.29
0.69
58.2
20.7
258.1
246.6
e9/l
2.51
421
4112
7
42
1.68
0.68
1.9
2.3
—
—
—
0
0
429
4205
1.29
0.68
58.1
20.7
91.2
91.1
fl
0.10
422
4153
23
305
0.74
0.68
1.4
1.4
—
—
—
0
0
429
4206
1.29
0.67
58.0
20.6
30.0
30.4
pg
4.00
422
4154
429
4207
1.28
0.66
58.2
20.7
4.3
4.6
e12/l
15.98
420
4105
429
4207
1.28
0.66
58.4
20.8
7.4
6.7
e9/l
7.99
421
4103
429
4209
1.28
0.64
58.8
20.8
127.4
137.7
g/l
24.02
422
4154
16
113
1.43
0.62
1.1
1.4
—
—
—
0
0
5
30
1.67
0.61
1.2
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
94
837
1.15
0.58
7.0
5.2
—
—
—
0
0
111
1005
1.14
0.54
1.5
1.4
—
—
—
0
0
16
121
1.33
0.45
1.1
1.4
—
—
—
0
0
7
51
1.38
0.44
1.3
1.2
0.3
0.5
nmol/l
—
7
45
16
122
1.32
0.43
1.1
1.4
—
—
—
0
0
16
123
1.31
0.41
1.1
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
315
3242
0.91
0.40
46.3
18.3
330.0
333.5
g/l
8.54
309
3228
8
61
1.32
0.39
2.1
2.5
—
—
—
0
0
16
124
1.30
0.39
1.1
1.4
—
—
—
0
0
5
37
1.36
0.37
1.2
1.2
—
—
—
0
0
162
1708
0.92
0.35
3.9
4.5
1.8
2.3
ug/l
0.84
135
1548
17
137
1.25
0.32
1.1
1.1
—
—
—
0
0
13
159
0.81
0.25
1.5
1.8
36.6
40.2
nmol/l
0.32
13
153
5
39
1.29
0.23
1.0
1.6
0.2
0.4
nmol/l
—
5
29
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
43
395
1.10
0.19
2.1
2.2
12.2
14.4
nmol/l
0.94
32
358
98
1020
0.95
0.15
6.9
3.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.3
—
—
—
0
0
5
48
1.04
0.09
1.4
1.2
—
—
—
0
0
16
175
0.91
0.08
1.0
1.1
—
—
—
0
0
83
814
1.02
0.04
6.2
3.6
1.0
1.0
kg/l
0.36
12
109
370
3688
1.02
0.03
6.8
4.5
7.8
6.0
mmol/l
17.39
331
3404
26
264
0.98
0.00
1.6
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
68.7
—
0
6
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
9.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
7
77
0.91
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
38.2
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_LATE_SYPHILIS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_LATE_SYPHILIS 3.108 [2.42, 4.0] < 0.001
Birth year 0.998 [0.99, 1.01] 0.642

During the follow-up period (1.1.1998 — 31.12.2019), 263 out of 865 females with AB1_LATE_SYPHILIS died.

Males

Parameter HR [95% CI] p-value
AB1_LATE_SYPHILIS 3.24 [2.65, 3.97] < 0.001
Birth year 0.985 [0.97, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 430 out of 1274 males with AB1_LATE_SYPHILIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_LATE_SYPHILIS.

N-year risk Females Males
1 0.383% 0.582%
5 1.782% 3.208%
10 4.899% 7.828%
15 9.863% 14.955%
20 16.506% 24.491%

Relationships between endpoints

Index endpoint: AB1_LATE_SYPHILIS – Late syphilis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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