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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasm of anus and anal canal

C3_ANUS_ANALCANAL

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C21
  • Cause of death: ICD-9 154[2-3]
  • Cause of death: ICD-8 1542
  • Cancer registry: Topography ICD-O-3 C21
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

176

4. Check minimum number of events

None

176

5. Include endpoints

None

176

6. Filter based on genotype QC (FinnGen only)

167

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 167 101 66
Unadjusted period prevalence (%) 0.03 0.04 0.03
Median age at first event (years) 66.58 63.68 71.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
176
Matched controls
1760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C21.1
ICD-10 Finland
Malignant neoplasm: Anal canal
+∞
144.3
118
*
C21.0
ICD-10 Finland
Malignant neoplasm: Anus, unspecified
+∞
107.7
92
*
A03FA01
ATC
metoclopramide; systemic, rectal
23.1
104.2
117
139
130
Kela drug reimbursment
Malignant tumour
+∞
103.7
89
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
25.5
101.8
89
68
UJH02
NOMESCO Finland
Anoscopy
26.5
83.3
65
38
WF002
NOMESCO Finland
Radical radiotherapy
431.0
80.8
75
*
8070/3-C21.0
ICD-O-3
Squamous cell carcinoma, NOS, of anus, NOS
+∞
70.7
63
*
JN4BD
NOMESCO Finland
Extensive body CT
23.7
69.9
56
34
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
65.8
59
*
N02AA05
ATC
oxycodone; systemic
11.8
61.8
94
156
8070/3-C21.1
ICD-O-3
Squamous cell carcinoma, NOS, of anal canal
+∞
57.5
52
*
Z51.5
ICD-10 Finland
Palliative care
22.4
54.1
43
25
L01BC06
ATC
capecitabine; oral
+∞
51.6
47
*
C21.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of rectum, anus and anal canal
+∞
50.5
46
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
44.7
41
*
JN4AD
NOMESCO Finland
Body CT examination
14.0
42.6
44
41
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
265.1
41.8
41
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
41.3
38
*
JG1CG
NOMESCO Finland
Extensive MRI of rectum
+∞
40.2
37
*
A04AA02
ATC
granisetron; systemic, transdermal
475.0
39.7
38
*
XX3DW
NOMESCO Finland
Time consuming IT work
12.8
38.7
42
42
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
34.5
32
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
33.4
31
*
UJF32
NOMESCO Finland
Coloscopy
5.9
30.8
94
288
H02AB02
ATC
dexamethasone; systemic
54.2
30.0
35
8
C20.99
ICD-10 Finland
Malignant tumor of the rectum other or unspecified histology
+∞
29.0
27
*
UJG02
NOMESCO Finland
Proctoscopy
43.2
28.7
35
10
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
172.4
28.6
29
*
JG1BG
NOMESCO Finland
MRI of rectum
+∞
27.8
26
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
26.7
25
*
A04AA01
ATC
ondansetron; systemic, rectal
27.9
26.5
36
16
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
24.5
23
*
TPH07
NOMESCO Finland
Cathetrisation of artery
6.4
24.5
49
100
JHA00
NOMESCO Finland
Anal or perianal incision
144.7
24.3
25
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
29.7
24.1
32
13
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
23.5
22
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.2
23.1
28
32
JHA10
NOMESCO Finland
Biopsy of anal canal
249.8
22.1
22
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.6
21.9
83
288
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
+∞
21.3
20
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
118.5
20.0
21
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.9
19.6
41
86
WX402
NOMESCO Finland
General anaesthesia
4.8
19.5
58
165
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
19.1
18
*
D75
ICPC
Malignant neoplasm colon/rectum
211.6
18.9
19
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
211.6
18.9
19
*
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
18.0
17
*
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
31.1
17.0
22
8
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
16.9
16
*
ULA02
NOMESCO Finland
Kolposcopy
6.2
16.8
32
61
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
19.6
16.1
24
14
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
21.8
16.0
23
12
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
16.9
15.9
25
17
Z93.3
ICD-10 Finland
Colostomy status
+∞
15.9
15
*
JFF23
NOMESCO Finland
Transversostomy
+∞
15.9
15
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
15.9
15
*
ZZR00
NOMESCO Finland
Flap of skin
174.9
15.7
16
*
WW500
NOMESCO Finland
Blood transfusion
17.1
15.4
24
16
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
14.8
14
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
14.8
14
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
14.8
14
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
14.8
14
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
33.1
14.2
18
6
WZC30
NOMESCO Finland
Teaching
4.5
14.2
41
112
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
+∞
13.7
13
*
C20
ICD-10 Finland
Malignant neoplasm of rectum
+∞
13.7
13
*
PJA12
NOMESCO Finland
Sentinel node biopsy
151.2
13.6
14
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.0
13.6
22
35
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
13.2
65
256
R4110
NOMESCO Finland
Physiotherapy
3.4
13.2
70
289
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
6.7
12.9
22
37
TJF80
NOMESCO Finland
Ostomy education
+∞
12.6
12
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
139.5
12.6
13
*
P01AB01
ATC
metronidazole; oral, rectal
3.1
12.4
101
531
R50.9
ICD-10 Finland
Fever, unspecified
3.9
11.9
41
127
B01AB10
ATC
tinzaparin; parenteral
4.6
11.8
31
78
A04AA55
ATC
palonosetron, combinations; systemic
+∞
11.6
11
*
JGB36
NOMESCO Finland
Wide excision of rectum
+∞
11.6
11
*
115
Kela drug reimbursment
Breast cancer
+∞
11.6
11
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
11.6
11
*
JN4CD
NOMESCO Finland
Very extensive body CT
23.2
10.9
15
7
L03AA13
ATC
pegfilgrastim; parenteral
64.0
10.8
12
*
WX600
NOMESCO Finland
Single shot through catheter
116.7
10.5
11
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
116.7
10.5
11
*
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
116.7
10.5
11
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
10.5
10
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
+∞
10.5
10
*
C21.2
ICD-10 Finland
Malignant neoplasm: Cloacogenic zone
+∞
10.5
10
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
12.4
10.3
18
16
B01AB05
ATC
enoxaparin; parenteral
2.8
10.2
77
379
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
5.4
10.1
21
43
K62.9
ICD-10 Finland
Disease of anus and rectum, unspecified
58.3
9.8
11
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
9.7
23
53
A04AD12
ATC
aprepitant; systemic
+∞
9.5
9
*
YL1CD
NOMESCO Finland
Very extensive CT examination of pelvis for dose design of radiotherapy
+∞
9.5
9
*
JGB37
NOMESCO Finland
Laparoscopic wide excision of rectum
+∞
9.5
9
*
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
+∞
9.5
9
*
A79
ICPC
Malignancy NOS
+∞
9.5
9
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
9.5
9
*
JG1DG
NOMESCO Finland
Very extensive MRI of rectum
+∞
9.5
9
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
9.4
45
171
SPAT1125
SPAT
Stoma care and guidance
19.9
9.1
13
7
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.3
9.1
19
39
TPX10
NOMESCO Finland
Implantation of vascular injection port
13.5
9.1
15
12
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.8
9.0
30
90
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.8
8.8
29
86
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
4.0
8.6
27
77
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
8.6
44
173
K61.0
ICD-10 Finland
Anal abscess
29.1
8.6
11
*
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
94.4
8.5
9
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
8.4
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
8.4
8
*
8140/3-C21.1
ICD-O-3
Adenocarcinoma, NOS, of anal canal
+∞
8.4
8
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.5
8.3
21
51
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
18.3
8.2
12
7
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
35.1
8.2
10
*
K60.2
ICD-10 Finland
Anal fissure, unspecified
23.3
8.1
11
5
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
8.0
52
232
A63.0
ICD-10 Finland
Anogenital (venereal) warts
11.6
8.0
14
13
JN3AD
NOMESCO Finland
Abdominal CT examination
3.7
7.9
27
82
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
7.7
33
116
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
6.8
7.5
18
29
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
+∞
7.3
7
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
7.3
7
*
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
+∞
7.3
7
*
8140/3-C21.0
ICD-O-3
Adenocarcinoma, NOS, of anus, NOS
+∞
7.3
7
*
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
+∞
7.3
7
*
JFF27
NOMESCO Finland
Laparoscopic sigmoidostomy
+∞
7.3
7
*
C80.91
ICD-10 Finland
Malignant tumor without specified localization epidermoid carcinoma
+∞
7.3
7
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
7.3
7
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
7.3
7
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.3
7
*
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
+∞
7.3
7
*
JN2DM
NOMESCO Finland
Lower part of abdomen very extensive MRI examination with Tesla magnet
+∞
7.3
7
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
7.1
7.3
17
26
N02AX02
ATC
tramadol; systemic, rectal
2.4
7.3
94
575
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
7.1
82
476
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
8.1
7.1
15
20
K60.3
ICD-10 Finland
Anal fistula
14.6
7.0
11
8
A06AD11
ATC
lactulose; oral
2.8
7.0
39
160
TQW99
NOMESCO Finland
Other minor procedure on skin
6.0
6.8
18
33
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.0
6.8
34
131
WX704
NOMESCO Finland
Intubation
4.2
6.6
18
46
Z2221
NOMESCO Finland
Medical doctor
2.4
6.5
58
298
ZXE00
NOMESCO Finland
One hour or less
2.3
6.5
77
448
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
72.4
6.5
7
*
ZZR10
NOMESCO Finland
Flap of skin and muscle
72.4
6.5
7
*
L02BA01
ATC
tamoxifen; oral
72.4
6.5
7
*
A28
ICPC
Limited function/disability NOS
2.6
6.5
46
213
WX892
NOMESCO Finland
Monitored bed care
3.7
6.4
21
62
L02BG04
ATC
letrozole; oral
27.8
6.3
8
*
JG1CM
NOMESCO Finland
Extensive MRI of rectum (more than 1.5 T)
+∞
6.3
6
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
6.3
6
*
ZZR30
NOMESCO Finland
Flap of muscle
+∞
6.3
6
*
C77.4
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Inguinal and lower limb lymph nodes
+∞
6.3
6
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
6.3
6
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
6.3
6
*
ZXD05
NOMESCO Finland
Urgent procedure
2.3
6.3
60
318
ZX120
NOMESCO Finland
Intravenous
3.8
6.1
19
54

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
111
64
45.25
149.20
4.3
1.4
5.05
2.84
ug/l
2.22
89
50
62
34
27.61
81.58
1.4
1.4
—
—
—
0
0
74
144
8.14
40.37
2.7
1.2
—
—
—
0
0
95
329
5.10
25.97
7.3
3.7
—
—
—
0
0
109
437
4.93
24.34
3.3
1.6
—
—
—
0
0
139
697
5.73
22.71
15.8
6.2
3.84
4.21
e9/l
0.99
121
615
102
444
4.09
19.09
7.3
1.9
2.36
2.35
mmol/l
0.42
93
374
61
184
4.54
19.00
3.7
2.2
0.75
0.83
mmol/l
5.06
56
168
43
99
5.42
18.54
1.3
1.1
—
—
—
0
0
82
315
4.00
18.22
6.2
3.1
93.21
88.30
%
0.88
82
307
74
288
3.71
15.73
11.3
4.2
—
—
—
0
0
55
175
4.12
15.65
3.1
2.4
18.94
23.77
%
1.99
48
152
48
141
4.31
15.17
2.1
1.8
10.82
6.93
umol/l
0.32
38
120
112
583
3.53
14.77
5.0
2.2
—
—
—
0
0
85
374
3.46
14.73
5.0
1.9
—
—
—
0
0
55
191
3.73
13.62
2.9
1.8
—
—
—
0
0
109
593
3.20
12.70
10.9
4.7
1.20
1.21
mmol/l
0.68
100
526
46
152
3.74
12.14
15.4
5.2
105.65
103.95
mmol/l
1.88
46
152
27
60
5.13
11.89
16.9
7.0
—
—
—
0
0
74
333
3.11
11.85
2.3
2.0
3.49
3.26
mg/l
0.18
56
273
23
45
5.73
11.62
1.9
1.4
6.31
3.02
ug/l
0.39
23
40
113
652
3.05
11.43
12.3
5.0
1.20
1.22
mmol/l
1.07
100
564
54
207
3.32
11.26
3.4
2.9
1.17
1.83
e6/l
0.48
29
102
116
686
3.03
11.09
13.4
14.8
1.34
1.34
inr
0.01
24
204
105
592
2.92
10.91
6.4
5.2
59.54
57.39
%
0.98
98
548
104
586
2.89
10.77
7.3
5.5
9.30
8.58
%
1.21
97
541
101
563
2.86
10.63
7.1
5.2
0.72
0.70
%
0.20
94
517
46
165
3.42
10.61
2.0
1.7
—
—
—
0
0
105
598
2.87
10.60
7.2
5.4
23.33
27.40
%
2.73
98
553
102
584
2.78
10.00
7.2
5.2
2.66
2.96
%
0.76
96
538
78
397
2.73
9.54
4.9
2.8
16.86
199.02
e6/l
0.56
58
296
77
392
2.71
9.38
6.1
2.8
7.41
7.40
ph
0.46
11
60
40
147
3.23
8.76
12.8
6.0
5.13
5.10
kpa
0.08
40
140
40
147
3.23
8.76
12.7
6.0
12.71
10.88
kpa
1.76
40
140
72
371
2.59
8.38
4.8
2.7
0.33
0.34
e6/l
0.01
52
269
36
128
3.28
8.30
2.4
1.9
30.86
30.44
u/l
0.04
29
105
37
134
3.23
8.28
13.6
6.2
95.89
94.64
%
0.27
37
129
70
359
2.58
8.19
4.7
2.7
—
—
—
0
0
103
634
2.51
8.13
6.8
5.2
0.62
0.59
e9/l
0.61
79
548
103
636
2.49
8.04
6.9
5.2
0.04
0.04
e9/l
0.64
79
551
84
474
2.48
7.97
6.1
3.4
36.34
64.83
e6/l
0.65
59
323
105
660
2.46
7.80
7.3
5.5
0.17
0.19
e9/l
0.58
81
581
103
647
2.43
7.59
7.0
5.3
1.58
1.82
e9/l
1.34
81
576
39
158
2.89
7.14
2.4
2.0
1.85
1.72
%
0.34
33
143
133
954
2.61
7.09
6.2
4.3
—
—
—
0
0
95
591
2.32
6.96
9.3
5.7
—
—
—
0
0
35
138
2.92
6.71
1.7
1.5
—
—
—
0
0
61
318
2.41
6.68
1.4
1.3
—
—
—
0
0
27
97
3.11
6.06
20.9
7.2
—
—
—
0
0
30
116
2.91
5.93
3.6
2.1
65.35
64.02
e9/l
0.06
19
87
64
363
2.20
5.60
1.5
1.6
19.06
20.89
nmol/l
0.37
54
313
88
572
2.08
5.35
3.4
2.6
215.47
120.68
ug/l
1.35
82
521
72
439
2.08
5.15
4.6
2.9
—
—
—
0
0
7
5
14.49
4.61
3.0
1.0
15.09
15.80
u/ml
—
7
5
91
631
1.92
4.32
2.0
2.0
85.50
96.77
pmol/l
1.51
48
307
41
223
2.09
3.84
2.5
1.8
30.03
29.26
s
0.31
41
210
23
101
2.47
3.54
2.1
1.3
—
—
—
0
0
7
10
7.23
3.39
2.6
1.2
—
—
—
0
0
9
19
4.93
3.28
1.0
1.3
—
—
—
0
0
81
577
1.75
3.25
16.9
7.7
0.01
0.00
e9/l
0.48
57
472
28
140
2.19
3.23
6.9
3.1
2.22
1.88
mmol/l
0.21
22
121
20
86
2.50
3.22
5.5
3.9
0.75
0.97
%
0.18
12
19
50
318
1.80
2.91
2.0
1.7
1.20
1.08
mg/l
0.20
39
253
15
59
2.69
2.87
1.6
1.2
—
—
—
0
0
18
78
2.46
2.85
5.5
4.0
1.00
0.21
%
1.31
11
14
27
140
2.10
2.84
7.0
3.1
5.60
5.80
kpa
0.61
27
135
20
93
2.30
2.73
1.5
1.2
—
—
—
0
0
5
7
7.31
2.56
2.0
2.1
485.00
882.57
e6/l
—
5
7
157
1402
2.11
2.50
34.8
12.0
31.80
21.12
mg/l
4.42
145
1071
10
34
3.06
2.32
9.3
2.6
—
—
—
0
0
126
1065
1.64
2.29
4.8
4.3
26.20
12.09
mm/h
7.55
118
965
7
18
4.00
2.27
1.3
1.0
—
—
—
0
0
17
83
2.16
2.09
6.1
4.0
0.10
0.06
%
—
10
16
18
90
2.11
2.09
5.7
4.2
—
—
—
0
0
5
10
5.11
2.08
1.4
3.5
—
—
—
0
0
8
27
3.05
1.96
10.3
1.5
46.63
63.53
%
—
8
27
5
11
4.64
1.95
6.4
1.3
—
—
—
0
0
5
11
4.64
1.95
1.2
1.1
7.72
10.80
%
—
5
11
31
469
0.59
1.93
3.1
3.2
—
—
—
0
0
21
115
1.94
1.93
1.8
1.3
—
—
—
0
0
86
684
1.50
1.91
7.0
5.2
0.00
0.00
estimate
-0.00
15
106
87
694
1.50
1.90
5.5
3.8
0.00
0.03
estimate
0.50
16
105
16
80
2.10
1.86
5.9
4.0
0.11
0.07
%
—
9
14
5
12
4.25
1.83
1.4
1.1
—
—
—
0
0
129
1429
0.64
1.81
4.5
4.8
1.47
1.50
mmol/l
0.47
118
1309
29
180
1.73
1.81
1.4
1.5
—
—
—
0
0
47
333
1.56
1.76
4.5
3.9
—
—
—
0
0
84
677
1.46
1.69
5.5
3.8
0.00
0.00
estimate
-0.00
16
118
5
14
3.64
1.62
1.2
1.1
—
—
—
0
0
5
14
3.64
1.62
1.4
1.6
—
—
—
0
0
11
50
2.28
1.60
2.8
2.0
21.00
21.40
s
0.18
11
45
5
15
3.40
1.53
1.2
1.0
—
—
—
0
0
60
463
1.45
1.48
2.1
2.0
248.87
147.84
u/l
0.81
55
429
5
16
3.18
1.45
9.8
5.0
6.60
6.68
mmol/l
—
5
11
42
304
1.50
1.42
3.5
3.6
81.92
163.84
ng/l
0.58
37
246
12
60
2.07
1.42
1.2
1.4
—
—
—
0
0
22
136
1.71
1.41
2.8
3.1
168.41
197.75
ng/l
0.21
17
122
7
29
2.47
1.40
1.7
1.5
—
—
—
0
0
0
39
0.00
1.35
0.0
1.2
—
—
—
0
0
14
76
1.91
1.34
6.4
2.2
0.64
0.65
%
0.10
14
76
6
25
2.45
1.25
1.5
1.1
—
—
—
0
0
118
1046
1.39
1.23
3.9
4.0
—
—
—
0
0
5
19
2.68
1.22
1.0
1.1
—
—
—
0
0
14
79
1.84
1.21
6.4
2.1
0.92
1.21
%
0.87
14
79
133
1437
0.70
1.20
4.4
4.9
4.72
4.66
mmol/l
0.23
122
1321
133
1437
0.70
1.20
5.1
4.9
6.08
5.99
mmol/l
0.30
120
1300
19
119
1.67
1.17
5.6
2.4
3.39
4.58
kpa
4.01
19
113
127
1381
0.71
1.17
6.0
6.2
40.01
40.11
mmol/mol
0.04
114
1270
7
31
2.31
1.11
1.0
1.2
—
—
—
0
0
20
129
1.62
1.11
6.3
3.6
—
—
—
0
0
40
301
1.43
1.11
1.7
1.7
923.67
1186.46
nmol/l
1.50
30
223
138
1474
0.70
1.05
5.0
5.5
2.79
2.73
mmol/l
0.29
125
1350
9
46
2.01
1.05
1.1
1.2
—
—
—
0
0
5
22
2.31
1.04
1.4
1.1
—
—
—
0
0
5
101
0.48
0.93
1.4
1.2
—
—
—
0
0
6
30
2.03
0.88
1.5
1.1
—
—
—
0
0
128
1372
0.75
0.86
3.9
4.3
1.35
1.27
mmol/l
0.81
115
1244
8
46
1.77
0.83
1.0
1.6
—
—
—
0
0
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
26
0.00
0.79
0.0
1.3
—
—
—
0
0
158
1513
1.43
0.70
39.9
14.2
79.50
77.84
umol/l
0.20
158
1513
10
61
1.68
0.70
1.5
1.2
—
—
—
0
0
7
44
1.61
0.66
3.7
3.6
—
—
—
0
0
10
143
0.68
0.50
1.3
1.5
—
—
—
0
0
42
361
1.21
0.46
6.6
3.9
0.00
0.00
estimate
-0.00
15
105
21
260
0.78
0.44
1.3
1.3
2.84
15.39
u/ml
—
7
93
38
326
1.21
0.43
1.7
1.8
408.33
451.95
pmol/l
0.48
33
264
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
41
358
1.19
0.39
5.5
3.3
—
—
—
0
0
9
68
1.34
0.38
1.3
1.3
—
—
—
0
0
152
1473
1.23
0.38
28.4
11.7
—
—
—
0
0
14
108
1.32
0.36
1.4
1.4
—
—
—
0
0
28
327
0.83
0.36
6.9
3.9
1.02
1.02
kg/l
—
6
43
6
44
1.38
0.35
9.8
4.6
—
—
—
0
0
6
45
1.34
0.34
5.2
5.1
22.37
25.31
mmol/l
—
6
40
7
97
0.71
0.31
1.1
1.1
—
—
—
0
0
17
206
0.81
0.31
1.5
1.2
—
—
—
0
0
13
102
1.30
0.31
9.7
3.1
—
—
—
0
0
7
55
1.28
0.30
3.7
4.1
—
—
—
0
0
45
496
0.88
0.29
3.7
3.2
112.27
183.91
mg/l
0.21
27
294
6
81
0.73
0.24
8.8
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
0.16
—
0
10
0
10
0.00
0.21
0.0
1.9
—
76.00
—
0
10
10
80
1.27
0.21
2.2
2.4
—
—
—
0
0
9
115
0.77
0.20
2.7
2.5
—
13.18
—
0
8
9
115
0.77
0.20
1.1
1.4
—
—
—
0
0
6
51
1.18
0.19
1.0
1.5
—
—
—
0
0
49
523
0.91
0.18
4.3
3.7
16.55
6.51
mg/mmol
0.86
30
302
159
1568
1.15
0.15
49.7
17.9
247.90
247.47
e9/l
0.02
154
1524
159
1569
1.14
0.14
52.0
17.9
36.60
40.22
%
11.81
149
1452
56
588
0.93
0.14
4.4
3.7
209.87
92.67
ng/l
0.32
40
411
11
94
1.18
0.13
2.5
2.7
—
—
—
0
0
130
1325
0.93
0.13
5.5
4.8
2.11
2.88
mu/l
0.39
119
1195
25
271
0.91
0.12
1.5
1.3
27.33
32.95
iu/ml
—
6
83
26
242
1.09
0.10
1.7
1.3
2.22
2.69
g/l
1.09
16
135
43
451
0.94
0.10
5.5
3.8
—
—
—
0
0
6
56
1.07
0.09
18.2
6.1
—
—
—
0
0
6
58
1.04
0.08
5.8
4.2
—
—
—
0
0
46
442
1.06
0.08
3.2
3.9
1.47
2.01
ug/l
0.69
38
392
16
148
1.09
0.06
1.8
2.7
4.76
6.49
ug/l
0.25
11
131
110
1093
1.02
0.01
4.6
3.9
15.37
14.83
pmol/l
0.49
100
983
24
246
0.97
0.00
1.5
2.6
0.46
0.75
ug/l
2.08
13
167
28
278
1.01
0.00
1.1
1.2
0.34
1.88
u/ml
—
5
77
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
9.56
—
0
9
0
9
0.00
-0.00
0.0
1.2
—
173.34
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1.60
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
2.6
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
172.89
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
62.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
1.11
—
0
9
7
73
0.96
-0.00
1.1
1.2
128.29
276.97
u/ml
—
7
66
12
120
1.00
-0.00
7.9
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_ANUS_ANALCANAL – Malignant neoplasm of anus and anal canal

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).