Multiple delivery

O15_DELIV_MULTIP

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O84
  • Hospital discharge: ICD-9 651.B
  • Hospital discharge: ICD-8 65007|6574
  • Cause of death: ICD-10 O84
  • Cause of death: ICD-9 651.B
  • Cause of death: ICD-8 65007|6574

2 out of 7 registries used, show all original rules.

3376

4. Check minimum number of events

None

3376

5. Include endpoints

None

3376

6. Filter based on genotype QC (FinnGen only)

3376

Control definitions (FinnGen only)

Control exclude
O15_DELIVERY

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O80-O84
Name in latin
Partus multiplex

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24092 24092 -
Only index persons 23570 23570 -
Unadjusted period prevalence (%)
Whole population 0.69 0.69 -
Only index persons 0.87 0.87 -
Median age at first event (years)
Whole population - 30.31 -
Only index persons - 30.31 -

-FinnGen-

Key figures

All Female Male
Number of individuals 3376 3376 -
Unadjusted period prevalence (%) 1.15 1.15 -
Median age at first event (years) 30.45 30.45 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3064
Matched controls
30640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O84.8
ICD-10 Finland
Other multiple delivery
+∞
323.0
310
*
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
+∞
323.0
681
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
12.5
323.0
713
725
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
+∞
323.0
529
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
+∞
323.0
829
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
12.2
323.0
778
829
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
+∞
323.0
502
*
O30.0
ICD-10 Finland
Twin pregnancy
251.7
323.0
1297
89
65007
ICD-8 Finland
Delivery without mention of complication, Multiple pregnancy, all presentations
+∞
323.0
536
*
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
323.0
525
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
38.4
323.0
688
229
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
18.8
323.0
523
331
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
13.4
323.0
1033
1121
Z39.2
ICD-10 Finland
Routine postpartum follow-up
13.8
323.0
592
524
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
+∞
323.0
732
*
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
1061.2
300.0
289
*
MAX99
NOMESCO Finland
Assistance to normal delivery
67.3
272.7
315
52
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
15.4
260.8
448
337
SPAT1380
SPAT
Postpartum check-up
25.7
249.6
356
156
O60
ICD-10 Finland
Preterm labour and delivery
19.2
241.6
379
223
SPAT1197
SPAT
Extensive health check-up of expecting family
11.7
240.8
471
469
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
6.7
238.1
672
1226
SPAT1379
SPAT
Health check-up of pregnant person
13.1
230.3
425
373
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
13.4
215.3
392
332
O81.4
ICD-10 Finland
Vacuum extractor delivery
+∞
215.1
204
*
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
12.7
210.2
393
352
W84
ICPC
Pregnancy high risk
27.7
206.0
287
114
Z37.2
ICD-10 Finland
Twins, both liveborn
197.4
196.6
203
11
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
50.3
195.2
237
51
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
661.3
191.1
187
*
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
12.6
183.8
343
303
W78
ICPC
Pregnancy
6.1
169.6
507
965
SPAT1196
SPAT
Monitoring of normal pregnancy
18.0
160.8
257
155
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
11.6
159.2
309
294
WX307
NOMESCO Finland
Obstetric epidural analgesia
13.5
150.8
271
218
XMA22
NOMESCO Finland
General examination of pregnant woman
13.2
141.0
256
210
O82.0
ICD-10 Finland
Delivery by elective caesarean section
+∞
136.5
130
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
6.3
128.9
367
644
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
9.8
121.2
255
280
MAE00
NOMESCO Finland
Outlet vacuum delivery
13.5
120.6
216
171
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
11.8
117.9
225
204
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
6.2
112.2
322
567
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
6.3
111.4
318
556
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
11.7
111.3
213
194
O32.1
ICD-10 Finland
Maternal care for breech presentation
9.6
109.0
232
259
65740
ICD-8 Finland
Occipital presentation
+∞
109.0
104
*
MAG00
NOMESCO Finland
Assisted breech delivery
165.9
107.0
112
7
O80.8
ICD-10 Finland
Other single spontaneous delivery
+∞
106.9
102
*
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
19.6
106.4
164
88
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
1053.2
104.9
102
*
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
14.0
104.2
183
138
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
4.3
101.3
416
1086
W90
ICPC
Uncompl labour/delivery livebirth
33.8
101.1
133
41
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
20.6
101.0
153
78
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
5.5
77.5
244
476
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
22.5
75.7
111
51
O80.1
ICD-10 Finland
Spontaneous breech delivery
+∞
73.2
70
*
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
17.1
72.6
117
71
65747
ICD-8 Finland
Multiple pregnancy, all presentations
+∞
71.1
68
*
O84.1
ICD-10 Finland
Multiple delivery, all by forceps and vacuum extractor
+∞
70.0
67
*
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
27.6
68.2
94
35
W85
ICPC
Gestational diabetes
9.2
66.9
144
163
SPAT1357
SPAT
Monitoring of problem during pregnancy
18.2
66.2
104
59
Z39.1
ICD-10 Finland
Care and examination of lactating mother
23.9
66.1
95
41
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
31.9
65.5
87
28
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
3.5
64.6
329
1017
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
8.0
62.3
146
190
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
+∞
61.7
59
*
O20.0
ICD-10 Finland
Threatened abortion
8.4
61.0
139
173
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
17.2
60.6
97
58
SPAT1189
SPAT
Other ultrasound examination during pregnancy
15.7
59.7
99
65
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
18.1
59.1
93
53
G03GA01
ATC
chorionic gonadotrophin; parenteral
3.2
56.3
328
1115
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
9.6
55.9
117
126
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
6.1
55.6
158
271
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
39.8
55.5
70
18
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
9.1
55.0
119
136
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
10.5
54.8
109
107
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
12.7
54.7
99
80
G02BA03
ATC
plastic IUD with progestogen
2.4
54.4
507
2297
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
10.3
54.2
109
109
G03DA04
ATC
progesterone; systemic, rectal, vaginal
3.3
54.0
302
996
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
12.3
53.3
98
82
O72.0
ICD-10 Finland
Third-stage haemorrhage
12.8
53.2
96
77
Z37.0
ICD-10 Finland
Single live birth
4.0
50.9
217
574
O99.80
ICD-10 Finland
The fear of childbirth
6.5
50.2
135
215
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
107.8
48.9
53
5
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
16.1
48.9
80
51
SPAT1200
SPAT
Guidance for breast-feeding and breast care
20.4
48.0
72
36
G03AC03
ATC
levonorgestrel; systemic
2.4
47.5
434
1936
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
12.7
46.4
84
68
TMA00
NOMESCO Finland
Episiotomy
11.6
46.1
87
77
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
28.7
45.7
62
22
Y6099
ICD-8 Finland
Prenatal care and observation
4.3
44.0
172
420
G03GA06
ATC
follitropin beta; parenteral
3.4
43.4
222
683
MA3AE
NOMESCO Finland
Combined first trimester screening
9.7
42.6
88
93
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
30.0
41.8
56
19
W92
ICPC
Compl labour/ delivery livebirth
10.5
41.4
82
80
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
15.8
41.4
68
44
Z30.2
ICD-10 Finland
Sterilization
2.4
40.6
377
1685
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
12.6
40.4
73
59
MAC96
NOMESCO Finland
Other induction or advancement of labour
9.3
40.2
85
94
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
7.3
40.2
99
140
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
3.4
40.1
210
657
Z36.8
ICD-10 Finland
Other antenatal screening
16.2
40.0
65
41
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
13.5
39.9
70
53
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
11.6
39.9
75
66
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
11.8
39.7
74
64
O83.0
ICD-10 Finland
Breech extraction
+∞
38.6
37
*
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
11.7
38.5
72
63
O47.9
ICD-10 Finland
False labour, unspecified
22.0
37.0
54
25
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
14.4
34.2
58
41
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
18.9
34.0
52
28
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
18.9
34.0
52
28
Z34
ICD-10 Finland
Supervision of normal pregnancy
5.5
33.7
102
190
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
+∞
32.3
31
*
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
8.5
32.1
71
85
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
3.7
32.0
145
405
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
4.0
31.8
132
341
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
2.1
31.3
407
2111
H01CA02
ATC
nafarelin; nasal
2.7
31.2
220
839
W29
ICPC
Pregnancy symptom/complaint other
9.3
30.6
64
70
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
6.9
30.4
77
114
8803
FHL
Stern exit
21.2
30.0
44
21
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
107.7
29.7
32
*
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
18.2
29.2
45
25
G03GA02
ATC
human menopausal gonadotrophin; parenteral
2.7
29.0
205
785
O02.1
ICD-10 Finland
Missed abortion
2.8
28.9
192
707
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.5
28.8
234
971
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
6.1
28.4
79
133
SPAT1316
SPAT
Extensive health check-up of children and adolescents
6.4
28.2
75
119
6511B
ICD-9 Finland
Multiple gestation, Triplet pregnancy[TRIGEMINI,SYNNYTYKSEN AIKANA]
+∞
28.2
27
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.3
27.9
66
2042
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
7.2
27.8
68
96
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
17.4
27.5
43
25
MAA00
NOMESCO Finland
Amniocentesis
5.6
27.3
81
148
O48
ICD-10 Finland
Prolonged pregnancy
8.6
27.0
59
70
SPAT1373
SPAT
Combined screening in early pregnancy
20.2
26.9
40
20
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
28.0
26.7
36
13
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
9.6
26.4
54
57
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
60.5
26.0
30
5
O69.0
ICD-10 Finland
Labour and delivery complicated by prolapse of cord
44.7
25.5
31
7
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
12.0
25.2
46
39
G03GB02
ATC
clomifene; oral
2.9
24.9
158
564
N81.6
ICD-10 Finland
Rectocele
3.0
23.9
139
470
N39.3
ICD-10 Finland
Stress incontinence
2.5
23.7
195
810
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
24.8
23.0
32
13
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.9
22.6
140
493
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
3.5
22.3
108
320
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.8
22.2
398
2310
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
7.5
22.1
52
70
65006
ICD-8 Finland
Delivery without mention of complication, Complete or incomplete breech presentation
+∞
21.9
21
*
O30.9
ICD-10 Finland
Multiple gestation, unspecified
63.0
21.9
25
*
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
80.7
21.7
24
*
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
4.7
21.6
74
160
MAG10
NOMESCO Finland
Breech extraction delivery
221.4
21.6
22
*
O41.0
ICD-10 Finland
Oligohydramnios
8.9
21.3
45
51
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
23.3
21.2
30
13
WX320
NOMESCO Finland
Spinalanesthesy
1.7
21.2
517
3298
G03GA05
ATC
follitropin alfa; parenteral
2.5
21.2
167
681
O40
ICD-10 Finland
Polyhydramnios
14.7
21.1
35
24
N97.0
ICD-10 Finland
Female infertility associated with anovulation
3.2
21.1
111
351
MBA04
NOMESCO Finland
Curettage of uterus after delivery
37.4
20.8
26
7
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
4.2
20.6
80
196
N81.1
ICD-10 Finland
Cystocele
2.9
20.6
129
457
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
4.6
20.4
72
161
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
7.2
20.3
49
69
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.0
20.2
121
415
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
5.6
19.9
58
105
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
8.9
19.8
42
48
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
3.1
19.3
110
366
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
16.8
19.1
30
18
O12.1
ICD-10 Finland
Gestational proteinuria
18.3
19.1
29
16
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
18.3
19.1
29
16
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
2.0
19.1
243
1243
O85
ICD-10 Finland
Puerperal sepsis
20.2
19.0
28
14
O14.1
ICD-10 Finland
Severe pre-eclampsia
8.2
18.9
42
52
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
18.9
1547
12847
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
18.8
2102
18481
O83.1
ICD-10 Finland
Other assisted breech delivery
+∞
18.8
18
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
6.1
18.7
51
85
SPAT1187
SPAT
General ultrasound examination in early pregnancy
17.2
18.7
29
17
O30.1
ICD-10 Finland
Triplet pregnancy
38.6
18.5
23
6
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
18.5
253
1330
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
15.1
18.4
30
20
6526B
ICD-9 Finland
Malposition and malpresentation of foetus, Multiple gestation with malpresentation of one foetus or more[MONISIKIÖN YHT ESIINT VIRHETARJ,SYNNYTYKSEN AIKANA]
25.2
18.2
25
10
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
11.1
18.2
34
31
SPAT1315
SPAT
Periodic health check-up of children and adolescents
3.9
18.1
75
196
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
7.1
18.1
44
63
N97.9
ICD-10 Finland
Female infertility, unspecified
1.9
18.0
284
1573
N05AX08
ATC
risperidone; systemic
0.4
17.9
55
1516
W12
ICPC
Contraception intrauterine
1.9
17.9
296
1670
SPAT1195
SPAT
Antenatal classes
4.8
17.7
59
125
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
4.9
17.7
58
121
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
12.5
17.6
31
25
WX234
NOMESCO Finland
Paracervical blockade
4.4
17.5
64
149
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
3.4
17.1
83
248
SPAT1391
SPAT
Counselling and guidance related to family situation
9.8
16.6
33
34
SPAT1193
SPAT
Pap smear
1.7
16.5
360
2216
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
8.6
16.4
35
41
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
23.2
16.4
23
10
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.1
16.3
5
554
SPAT1263
SPAT
Sampling
1.4
16.3
1050
8273
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
3.4
15.8
77
231
L02AE01
ATC
buserelin; implant, nasal, parenteral
2.8
15.7
102
373
O84.9
ICD-10 Finland
Multiple delivery, unspecified
+∞
15.6
15
*
O61.0
ICD-10 Finland
Failed medical induction of labour
6.7
15.5
39
59
Z36.9
ICD-10 Finland
Antenatal screening, unspecified
10.8
15.4
29
27
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
3.6
15.4
69
194
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
6.7
15.2
38
57
O47
ICD-10 Finland
False labour
16.1
15.2
24
15
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
13.1
15.2
26
20
65400
ICD-8 Finland
Occipital presentation
0.1
15.1
9
613
N05AH03
ATC
olanzapine; systemic
0.4
15.1
63
1532
103
Kela drug reimbursment
Diabetes, insulin-treated
0.6
15.1
255
4032
A05AA02
ATC
ursodeoxycholic acid; oral
3.9
15.0
62
163
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
8.1
15.0
33
41
N05AX12
ATC
aripiprazole; systemic
0.3
14.8
36
1099
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
11.3
14.7
27
24
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
18.4
14.7
22
12
6511A
ICD-9 Finland
Multiple gestation, Triplet pregnancy[TRIGEMINI,RASKAUDEN AIKANA]
80.5
14.6
16
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.6
14.5
252
3959
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
9.4
14.4
29
31
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
5.8
14.3
40
70
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.9
14.3
89
318
LCD10
NOMESCO Finland
Vaginal hysterectomy
2.7
14.1
95
354
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.3
14.1
31
993
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
14.1
990
7871
OAA12
SPAT
NA
14.5
14.0
23
16
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
14.0
1576
13507
SPAT1383
SPAT
Extensive health check-up at 4 years of age
10.1
13.9
27
27
O46.8
ICD-10 Finland
Other antepartum haemorrhage
53.6
13.8
16
*
J01DA01
ATC
[U] cefalexin; systemic
1.3
13.7
1769
15463
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
5.6
13.7
39
70
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
4.6
13.7
47
104
W05
ICPC
Pregnancy vomiting/nausea
13.6
13.7
23
17
O62.1
ICD-10 Finland
Secondary uterine inertia
9.1
13.7
28
31
8221
FHL
Sterilization of the laparotomy pathway
2.5
13.7
108
444
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.5
13.6
63
183
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
13.5
1856
16364
O99.7
ICD-10 Finland
Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
140.6
13.5
14
*
MA3AE
SPAT
NA
140.6
13.5
14
*
Z39
ICD-10 Finland
Postpartum care and examination
8.1
13.3
29
36
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.1
13.2
5
471
XMA20
NOMESCO Finland
Early examination of pregnancy
9.7
13.2
26
27
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
6.4
13.2
34
54
G02CB01
ATC
bromocriptine; systemic
2.9
13.2
78
271
O12.0
ICD-10 Finland
Gestational oedema
15.1
13.1
21
14
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
16.8
13.0
20
12
MBA20
NOMESCO Finland
Expression of placenta
50.2
12.8
15
*
SPAT1303
SPAT
Counselling and guidance related to growth and development
10.5
12.7
24
23
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.1
12.6
*
378
Z36.1
ICD-10 Finland
Antenatal screening for raised alphafetoprotein level
70.1
12.6
14
*
O21
ICD-10 Finland
Excessive vomiting in pregnancy
11.0
12.5
23
21
SPAT1192
SPAT
Gynaecological examination
1.6
12.3
309
1971
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.7
12.3
239
1416
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
12.3
667
5044
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
12.3
1635
14248
N05AF03
ATC
chlorprothixene; systemic
0.2
12.3
14
637
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
8.4
12.2
26
31
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
9.0
12.2
25
28
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
12.4
12.1
21
17
N05AH02
ATC
clozapine; systemic
0.2
12.1
8
511
P72
ICPC
Schizophrenia
0.1
12.1
5
441
XMA00
NOMESCO Finland
NA
11.1
12.0
22
20
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
8.7
12.0
25
29
K02.1
ICD-10 Finland
Caries of dentine
1.3
12.0
1592
13849
63499
ICD-8 Finland
Other complications of pregnancy, Other
4.0
11.8
46
116
SPAT1308
SPAT
Sexual health counselling
1.6
11.8
344
2279
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
9.6
11.7
23
24
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
3.4
11.7
55
163
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
16.4
11.7
18
11
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
30.1
11.6
15
5
SPAT1188
SPAT
Monitoring of foetal growth
120.4
11.4
12
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.4
11.4
99
428
N03AG01
ATC
valproic acid; systemic, rectal
0.4
11.4
59
1319
N05AB03
ATC
perphenazine; systemic, rectal
0.3
11.4
27
835
63702
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Oedema
7.9
11.3
25
32
O36.4
ICD-10 Finland
Maternal care for intrauterine death
9.6
11.2
22
23
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
11.2
1333
11374
63496
ICD-8 Finland
Other complications of pregnancy, Labores inhibiti
6.8
11.1
27
40
SPAT1324
SPAT
Screening procedure
1.4
11.1
745
5832
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
12.7
11.1
19
15
SGA01
NOMESCO Finland
Tooth opening as first aid
1.5
11.1
438
3105
N05BA06
ATC
lorazepam; systemic, sublingual
0.3
11.0
32
903
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
10.1
11.0
21
21
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.6
10.9
308
2027
MAC00
NOMESCO Finland
Rupture of amniotic membrane
43.4
10.9
13
*
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.6
10.9
222
3381
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
10.6
10.8
20
19
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
10.5
1092
9120
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
6.5
10.5
26
40
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
14.2
10.5
17
12
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
0.2
10.4
9
481
65746
ICD-8 Finland
Complete or incomplete breech presentation
+∞
10.4
10
*
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
16.1
10.3
16
10
WX290
NOMESCO Finland
Other blockade of nerve
1.3
10.3
1277
10914
J01CA04
ATC
amoxicillin; systemic
1.3
10.2
2343
21730
W94
ICPC
Puerperal mastitis
23.4
10.2
14
6
Z30.5
ICD-10 Finland
Surveillance of (intrauterine) contraceptive device
1.7
10.2
204
1221
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
6.2
10.1
26
42
LGA21
NOMESCO Finland
Laparoscopic sterilisation by constriction of Fallopian tubes
1.8
10.1
177
1016
LEG10
NOMESCO Finland
Vaginal urethrocystopexy
3.0
10.0
55
184
1412
FHL
Laparoscopy and sterilization
1.8
10.0
156
866
J01CA08
ATC
pivmecillinam; oral
1.3
10.0
1409
12235
N05AH04
ATC
quetiapine; oral
0.7
9.9
301
4247
XCK10
NOMESCO Finland
Photography of fundus of eye
0.5
9.9
77
1506
Z31.2
ICD-10 Finland
In vitrofertilization
3.5
9.9
44
126
SPAT1382
SPAT
Extensive health check-up at 18 months of age
10.6
9.8
18
17
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
0.3
9.7
27
774
N05AA02
ATC
levomepromazine; systemic
0.4
9.7
29
805
O31.8
ICD-10 Finland
Other complications specific to multiple gestation
55.1
9.6
11
*
O64.4
ICD-10 Finland
Obstructed labour due to shoulder presentation
55.1
9.6
11
*
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
4.4
9.6
33
75
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
2.1
9.5
111
549
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
9.5
227
1428
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
10.0
9.5
18
18
SPAT1381
SPAT
Extensive health check-up at 4 months of age
15.1
9.5
15
10
N05CD07
ATC
temazepam; oral
0.6
9.4
109
1899
L02AE02
ATC
leuprorelin; implant, parenteral
2.3
9.4
83
363
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.7
9.4
60
221
O43.0
ICD-10 Finland
Placental transfusion syndromes
30.1
9.4
12
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.4
1335
11570
PHD99
NOMESCO Finland
Resection of other vein
1.8
9.3
150
838
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
8.7
9.3
19
22
TLW00
NOMESCO Finland
Insemination
2.4
9.2
76
321
QBJ30
NOMESCO Finland
Correction of abdominal apron
3.3
9.2
44
134
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
9.1
1430
12526
O62.2
ICD-10 Finland
Other uterine inertia
11.5
9.1
16
14
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
8.3
9.1
19
23
63899
ICD-8 Finland
Hyperemesis gravidarum, Without mention of neuritis
9.0
9.0
18
20
A10AA01
ATC
NA
0.3
9.0
22
667
W99
ICPC
Disorder of pregn/delivery other
18.6
8.9
13
7
W18
ICPC
Post-partum symptom/complaint other
18.6
8.9
13
7
O21.1
ICD-10 Finland
Hyperemesis gravidarum with metabolic disturbance
24.1
8.9
12
5
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.4
8.9
501
3797
8811
FHL
Cesarean section
1.4
8.7
370
2657
G03GA04
ATC
urofollitropin; parenteral
2.7
8.7
59
224
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.3
8.7
22
658
W30
ICPC
Pregnancy, Medical examin/health eval complete
14.1
8.7
14
10
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
50.1
8.7
10
*
G01AA10
ATC
clindamycin; vaginal
1.4
8.7
538
4138
LGA22
NOMESCO Finland
Hysteroscopic sterilisation
3.4
8.6
40
120
8502
FHL
Evacuation and abrasion
1.9
8.6
129
709
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
8.2
8.6
18
22
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
11.6
8.6
15
13
O32.0
ICD-10 Finland
Maternal care for unstable lie
11.6
8.6
15
13
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
2.9
8.6
50
175
W03
ICPC
Antepartum bleeding
6.9
8.5
20
29
H01CC01
ATC
ganirelix; parenteral
1.9
8.5
114
598
N05CF01
ATC
zopiclone; oral
0.8
8.5
554
6937
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
0.3
8.5
13
496
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
0.1
8.4
*
319
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
2.3
8.4
74
327
O31.2
ICD-10 Finland
Continuing pregnancy after intrauterine death of one fetus or more
+∞
8.3
8
*
XMA02
NOMESCO Finland
Fetal heart ultrasound examination
+∞
8.3
8
*
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
10.8
8.3
15
14
W27
ICPC
Fear of complications of pregnancy
7.1
8.2
19
27
6282B
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE SEC]
3.9
8.2
32
83
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.0
8.2
95
474
N97.4
ICD-10 Finland
Female infertility associated with male factors
2.2
8.2
83
391
A10AA02
ATC
NA
0.4
8.2
25
684
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
7.5
8.1
18
24
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
8.1
1028
8735
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.6
8.0
194
1228
67008
ICD-8 Finland
Sepsis of childbirth and the puerperium, Alia definita
6.3
8.0
20
32
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.5
8.0
282
1954
N05BA01
ATC
diazepam; systemic, rectal
0.7
8.0
189
2797
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.9
892
7460
205
Kela drug reimbursment
Chronic hypertension
0.7
7.8
204
2957
N05AF05
ATC
zuclopenthixol; systemic
0.0
7.7
*
193
O32.5
ICD-10 Finland
Maternal care for multiple gestation with malpresentation of one fetus or more
45.1
7.7
9
*
W28
ICPC
Limited function/disability (W)
45.1
7.7
9
*
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
15.0
7.7
12
8
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.4
7.6
354
2587
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
3.1
7.6
40
132
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
7.6
649
5228
63501
ICD-8 Finland
Urinary infections arising during pregnancy and the puerperium, Pyelitis et pyelocystitis
11.9
7.6
13
11
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.6
700
5706
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
3.8
7.5
30
80
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.5
7.4
53
211
OAA11
SPAT
NA
2.7
7.3
48
182
KMAK
NOMESCO Finland
NA
1.2
7.3
1498
13394
65004
ICD-8 Finland
Delivery without mention of complication, Occipital presentation, posterior position
+∞
7.3
7
*
MAC98
NOMESCO Finland
Other induction of labor
+∞
7.3
7
*
O30
ICD-10 Finland
Multiple gestation
+∞
7.3
7
*
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
9.4
7.3
14
15
N05AA01
ATC
chlorpromazine; systemic, rectal
0.1
7.3
*
289
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
4.4
7.1
24
55
M62.0
ICD-10 Finland
Diastasis of muscle
7.9
7.1
15
19
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.0
7.1
38
128
Z29
ICPC
Social problem NOS
2.8
7.1
43
157
J01AA02
ATC
doxycycline; systemic
1.2
7.0
2215
20713
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
1.9
6.9
91
478
H04AA01
ATC
glucagon; nasal, parenteral
0.3
6.9
15
476
188
Kela drug reimbursment
Psychosis requiring demanding treatment
0.2
6.8
5
294
N05AD01
ATC
haloperidol; systemic
0.3
6.8
12
428
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
6.7
6.8
16
24
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.7
6.8
44
166
OAB42
SPAT
NA
0.4
6.7
34
764
WX110
NOMESCO Finland
Local anesthesy
1.2
6.7
1919
17697
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.5
6.7
45
916
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
3.0
6.7
36
122
SGB30
NOMESCO Finland
Other demanding filling of root channel of tooth
1.4
6.4
302
2214
JAF10
NOMESCO Finland
Repair of umbilical hernia
2.9
6.4
37
129
SGC10
NOMESCO Finland
Covering pulpa of tooth
1.5
6.4
240
1682
Z35.6
ICD-10 Finland
Supervision of very young primigravida
70.0
6.4
7
*
O30.02
ICD-10 Finland
Twin pregnancy with a shared amniotic and chorionic sac
70.0
6.4
7
*
N04AA02
ATC
biperiden; systemic
0.3
6.4
12
414
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
14.3
6.4
10
7
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
14.3
6.4
10
7
PHD76
NOMESCO Finland
Resection of long saphenous vein
1.8
6.3
102
574
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
8.2
6.3
13
16
G01AF05
ATC
econazole; vaginal
1.4
6.3
273
1973
N05AN01
ATC
lithium; oral
0.4
6.3
20
537
O90.1
ICD-10 Finland
Disruption of perineal obstetric wound
+∞
6.2
6
*
Z36
ICD-10 Finland
Antenatal screening
+∞
6.2
6
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
0.1
6.2
*
214
G03HB01
ATC
cyproterone and estrogen; systemic
0.7
6.2
283
3745
Z16
ICPC
Relationship problem with child
7.0
6.2
14
20
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
6.3
6.2
15
24
B02AA02
ATC
tranexamic acid; systemic
1.3
6.1
514
4123
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
7.7
6.1
13
17
W19
ICPC
Lactation symptom/complaint
7.7
6.1
13
17
N06AX11
ATC
mirtazapine; oral
0.8
6.1
650
7721
O90.9
ICD-10 Finland
Complication of the puerperium, unspecified
12.5
6.1
10
8
SPAT1228
SPAT
Forms of educational rehabilitation therapy
12.5
6.1
10
8
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
0.5
6.0
33
718
SPAT1301
SPAT
No procedures
1.3
6.0
655
5432
N03AX09
ATC
lamotrigine; oral
0.6
6.0
71
1225

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
128
220
6.01
71.40
2.6
1.6
7.4
7.6
umol/l
0.06
101
160
209
543
4.04
71.39
1.5
1.1
—
—
—
0
0
551
2805
2.15
53.13
1.7
1.5
—
—
—
0
0
83
147
5.76
44.86
1.2
1.1
—
—
—
0
0
509
2866
1.91
36.04
2.1
1.6
—
—
—
0
0
157
532
3.05
35.43
1.5
1.2
—
—
—
0
0
37
37
10.10
32.72
3.5
1.9
—
—
—
0
0
711
4731
1.64
27.48
1.8
1.6
—
—
—
0
0
137
498
2.83
27.26
1.3
1.1
—
—
—
0
0
923
11237
0.75
11.59
1.8
1.9
99.1
99.9
pmol/l
0.21
493
5600
788
6264
1.34
10.79
1.9
2.0
—
—
—
0
0
306
2117
1.49
9.33
3.5
3.8
—
—
—
0
0
1001
11809
0.78
9.22
4.2
4.7
36.4
36.3
g/l
0.46
939
11005
1430
12527
1.25
8.67
4.2
3.4
—
—
—
0
0
804
6614
1.28
8.26
3.7
3.9
0.0
0.0
estimate
0.32
330
2314
1046
12124
0.80
7.89
5.1
5.7
1.2
1.2
mmol/l
0.14
958
11090
680
8279
0.78
7.80
3.3
4.1
7.4
7.4
ph
0.03
149
1347
462
5923
0.75
7.78
1.5
1.5
21.7
21.6
nmol/l
0.01
402
5189
618
7575
0.77
7.42
3.2
3.8
98.8
98.7
%
0.01
600
7326
88
476
1.87
7.05
1.4
1.1
—
—
—
0
0
88
477
1.87
7.01
1.4
1.1
—
—
—
0
0
846
9878
0.81
6.50
3.4
3.4
2.4
2.4
mmol/l
0.13
752
8784
249
1783
1.43
6.38
2.4
2.1
6577.6
2857.4
u/l
1.20
104
635
1924
17696
1.20
6.37
4.0
4.0
1243.5
1850.6
e6/l
0.23
12
161
225
1582
1.45
6.36
2.8
2.7
—
—
—
0
0
1179
13283
0.83
6.25
5.8
6.5
1.2
1.2
mmol/l
0.50
993
11364
573
6943
0.79
6.09
3.3
3.5
437.7
368.8
mg/l
0.11
333
4098
1231
13789
0.83
6.08
2.2
2.4
76.5
76.2
nmol/l
0.18
1151
12818
147
2205
0.65
6.05
3.2
4.1
75.5
83.8
ng/l
0.65
128
1952
986
8550
1.22
6.02
2.1
2.2
—
—
—
0
0
1251
13982
0.83
6.00
5.6
6.7
0.7
0.7
%
1.76
1164
13110
129
1985
0.64
5.98
6.2
4.6
1.8
1.8
mmol/l
0.03
100
1615
1334
14814
0.84
5.93
5.3
6.4
56.1
56.5
%
0.56
1250
13996
1298
14429
0.84
5.79
5.6
6.5
2.9
2.7
%
2.61
1206
13557
124
1904
0.64
5.70
10.5
9.4
—
—
—
0
0
350
4477
0.76
5.67
1.8
1.7
1161.6
1184.5
nmol/l
0.20
278
3395
1356
14992
0.84
5.62
5.5
6.6
30.1
29.5
%
1.28
1268
14145
692
8148
0.81
5.61
6.2
7.9
—
—
—
0
0
395
4964
0.77
5.60
2.9
2.7
2.4
2.4
mmol/l
0.58
346
4320
64
1155
0.55
5.57
9.8
5.3
24.1
24.2
mmol/l
0.12
54
1049
608
7246
0.80
5.51
4.0
4.2
9.6
9.8
mg/mmol
0.03
352
4378
1613
17553
0.84
5.49
7.9
10.5
3.9
4.0
e9/l
0.38
1430
15449
1439
15808
0.84
5.47
5.4
6.5
1.9
2.0
e9/l
0.49
1297
14103
1390
15311
0.84
5.45
5.4
6.5
0.5
0.5
e9/l
1.42
1231
13456
1310
14495
0.84
5.40
5.8
6.8
8.0
8.1
%
0.32
1230
13709
26
95
2.75
5.36
1.3
1.2
—
—
—
0
0
1397
15353
0.85
5.26
5.5
6.5
0.0
0.0
e9/l
0.02
1232
13459
3128
30480
1.36
5.06
10.1
11.2
—
—
—
0
0
255
3356
0.74
5.03
4.6
6.2
1.0
1.0
mmol/l
0.88
240
3145
676
7904
0.82
5.03
3.1
3.4
7.1
6.9
mmol/l
0.64
589
6769
175
1232
1.44
4.98
1.8
1.9
—
—
—
0
0
1457
15907
0.85
4.92
5.5
6.9
0.2
0.2
e9/l
1.46
1309
14115
593
6973
0.82
4.63
1.6
1.4
2.1
2.2
g/l
0.48
381
4283
26
103
2.54
4.62
2.6
2.7
12.2
7.4
mg/l
0.86
18
86
224
2951
0.74
4.46
2.2
2.5
30.7
35.0
u/l
1.36
195
2480
180
2443
0.72
4.35
7.5
7.4
5.2
5.1
kpa
0.30
174
2333
180
2442
0.72
4.34
7.5
7.4
13.5
13.3
kpa
0.15
175
2335
360
4425
0.79
4.22
3.1
3.3
0.8
0.8
mmol/l
0.56
335
4121
1261
11450
1.16
4.19
2.3
2.5
—
—
—
0
0
181
2438
0.73
4.18
7.4
7.4
0.6
1.0
mmol/l
0.56
143
1908
891
7878
1.18
4.14
1.9
1.3
—
—
—
0
0
740
6449
1.19
4.07
2.1
2.1
—
—
—
0
0
1476
13583
1.15
4.04
3.4
3.5
0.0
0.0
estimate
1.95
333
2294
2711
28002
0.84
3.92
10.8
13.9
39.5
39.6
%
0.30
2120
22567
1453
13383
1.15
3.88
3.3
3.4
0.0
0.0
estimate
0.80
317
2244
21
478
0.44
3.74
1.4
1.7
44.7
60.0
mu/l
0.66
21
423
1461
13487
1.15
3.73
4.4
4.8
0.0
0.0
estimate
1.34
327
2339
918
10229
0.86
3.73
5.5
6.5
—
—
—
0
0
2510
26043
0.86
3.58
13.0
16.2
331.7
331.0
g/l
4.27
2495
25870
279
3456
0.79
3.50
2.2
2.6
9.2
6.3
umol/l
0.82
243
2841
2510
26020
0.86
3.43
4.4
5.2
37.7
38.8
mmol/mol
9.07
2348
24502
5
194
0.26
3.36
1.8
1.5
—
—
—
0
0
236
2960
0.78
3.30
1.2
1.2
—
—
—
0
0
64
998
0.63
3.28
1.9
1.3
4.6
2.7
ug/l
1.39
57
879
206
2622
0.77
3.24
2.0
2.3
0.2
0.2
g/l
0.34
195
2454
375
4460
0.82
3.23
2.5
2.3
111.2
97.8
ug/g
0.39
303
3480
20
84
2.39
3.22
1.3
1.2
—
—
—
0
0
194
2464
0.77
3.02
2.5
2.5
1.7
1.8
%
1.68
173
2153
234
2892
0.79
2.91
1.4
1.5
—
—
—
0
0
22
441
0.50
2.84
1.3
1.4
238.2
417.5
pmol/l
1.67
17
350
48
769
0.62
2.82
2.8
3.6
1.4
1.5
mg/l
0.33
40
715
3288
32519
1.43
2.77
15.9
18.7
30.1
30.0
pg
0.38
3260
32161
3289
32531
1.43
2.77
16.1
18.8
133.0
133.0
g/l
0.04
3261
32177
3286
32498
1.42
2.75
16.0
18.8
264.8
274.6
e9/l
16.99
3232
31813
817
7380
1.14
2.72
2.9
3.0
—
—
—
0
0
3288
32524
1.42
2.72
16.0
18.8
4.4
4.5
e12/l
0.46
3226
31796
63
941
0.66
2.70
1.2
1.3
—
—
—
0
0
73
496
1.48
2.64
1.7
1.7
—
—
—
0
0
3288
32532
1.41
2.63
16.1
18.8
6.5
6.6
e9/l
0.94
3221
31793
3287
32521
1.41
2.62
16.0
18.7
90.4
90.5
fl
0.64
3259
32165
1974
18822
1.12
2.59
4.0
4.2
—
—
—
0
0
1825
19163
0.90
2.57
3.0
3.1
—
—
—
0
0
96
1308
0.73
2.49
9.6
9.9
94.6
94.2
%
0.40
96
1300
60
887
0.67
2.47
2.9
3.2
223.1
354.0
u/ml
0.32
50
747
104
1397
0.74
2.47
1.7
1.7
—
—
—
0
0
134
1030
1.31
2.38
2.2
3.1
—
—
—
0
0
97
1307
0.73
2.36
9.5
9.9
1.3
1.3
%
0.07
97
1296
265
3151
0.83
2.31
2.4
2.1
367.5
376.8
nmol/l
0.42
251
2883
728
6598
1.13
2.28
2.9
3.2
—
—
—
0
0
164
2046
0.79
2.26
7.6
8.1
96.3
96.0
%
0.23
157
1970
36
582
0.61
2.26
1.1
1.1
—
—
—
0
0
21
106
1.99
2.25
3.3
2.9
—
—
—
0
0
2031
21121
0.90
2.20
2.7
3.0
33.6
39.3
u/l
4.38
1926
20019
13
54
2.41
2.19
1.2
1.2
34.7
37.4
g/l
—
8
32
9
214
0.42
2.17
1.3
3.4
—
—
—
0
0
349
4025
0.85
2.15
2.2
2.7
5.2
5.2
e6/l
0.02
176
1992
55
799
0.68
2.11
7.3
4.6
—
—
—
0
0
98
1292
0.75
2.09
9.4
10.0
0.7
0.7
%
0.01
98
1281
638
5770
1.13
2.06
1.3
1.3
8.0
13.4
u/ml
1.48
264
2321
345
3968
0.85
2.06
2.2
2.6
2.5
2.4
g/l
1.00
315
3690
2101
21764
0.91
1.98
6.6
7.6
72.9
76.2
u/l
3.95
2002
20599
79
580
1.37
1.96
2.0
2.2
—
—
—
0
0
860
7936
1.11
1.96
2.5
2.7
—
—
—
0
0
97
1263
0.76
1.92
6.4
4.5
—
—
—
0
0
69
941
0.73
1.88
8.0
3.5
1.4
1.3
%
0.05
69
932
85
1122
0.75
1.86
8.1
9.5
—
—
—
0
0
319
3658
0.86
1.85
2.2
2.7
25.0
23.0
%
1.35
282
3200
31
490
0.63
1.83
16.3
4.2
—
—
—
0
0
716
7785
0.90
1.81
1.6
1.7
1.3
1.4
mmol/l
1.20
607
6821
736
7988
0.90
1.80
1.3
1.3
1.9
1.7
u/ml
0.16
239
2104
230
2699
0.84
1.78
3.6
3.5
22.5
10.5
ug/l
0.45
169
2018
600
5463
1.12
1.74
3.4
3.7
1.0
1.0
kg/l
0.08
112
726
44
636
0.69
1.71
1.1
1.3
—
—
—
0
0
0
46
0.00
1.70
0.0
1.0
—
0.5
—
0
34
29
180
1.62
1.66
1.4
1.5
5.6
7.0
mmol/l
1.32
21
115
311
3541
0.87
1.66
1.4
1.5
—
—
—
0
0
40
585
0.68
1.66
1.1
1.1
—
—
—
0
0
141
1719
0.81
1.65
3.0
2.6
69.1
72.1
e9/l
0.57
99
1223
21
120
1.75
1.62
3.3
2.8
—
—
—
0
0
9
186
0.48
1.61
1.2
1.2
—
—
—
0
0
84
648
1.30
1.56
1.3
1.5
—
—
—
0
0
70
920
0.76
1.54
7.9
3.6
0.7
0.6
%
0.67
65
880
5
15
3.34
1.52
4.0
3.5
—
—
—
0
0
37
538
0.68
1.51
2.1
2.5
15.3
68.4
ug/min
4.44
24
336
70
916
0.76
1.50
1.4
1.3
131.3
169.2
titre
—
8
86
49
674
0.72
1.47
7.8
4.0
1.2
1.4
mmol/l
1.45
49
658
33
487
0.67
1.46
1.2
1.1
51.8
2738.6
iu/ml
0.50
13
98
5
16
3.13
1.44
4.2
3.4
—
—
—
0
0
278
3152
0.87
1.42
1.3
1.4
—
—
—
0
0
1532
14687
1.08
1.42
3.9
4.4
6.3
6.6
mmol/l
6.56
1401
13775
70
907
0.77
1.41
1.7
1.7
—
—
—
0
0
83
1051
0.78
1.40
1.1
1.2
—
—
—
0
0
32
469
0.68
1.38
1.2
1.3
0.1
0.2
nmol/l
—
5
31
13
67
1.94
1.38
1.0
1.5
—
—
—
0
0
201
2327
0.86
1.37
3.7
2.7
10.4
10.3
g/l
0.06
191
2150
538
5851
0.90
1.37
3.8
4.3
—
—
—
0
0
42
583
0.72
1.35
1.4
3.1
0.8
0.8
nmol/l
0.16
37
474
390
4309
0.89
1.33
2.2
2.6
1.5
1.3
e6/l
0.26
216
2261
10
47
2.13
1.33
1.4
1.8
—
—
—
0
0
156
1837
0.84
1.32
2.1
1.9
1.2
1.4
g/l
1.19
148
1698
28
416
0.67
1.31
1.5
1.5
68.4
62.1
mmol/l
0.37
22
314
28
185
1.52
1.29
1.6
1.8
3.1
2.8
u/field
0.08
18
103
2942
29004
1.11
1.28
10.6
12.3
18.0
19.8
mg/l
2.45
2277
22390
5
117
0.43
1.24
1.0
1.0
—
—
—
0
0
79
987
0.80
1.22
2.3
1.4
0.4
0.4
nmol/l
0.38
60
763
7
145
0.48
1.19
2.6
3.0
—
—
—
0
0
9
168
0.53
1.18
1.8
1.3
—
—
—
0
0
884
8350
1.08
1.18
2.5
2.8
21.3
105.3
ng/l
0.61
434
4338
55
419
1.32
1.18
3.1
3.3
18.9
25.1
mg/l
0.93
39
248
20
310
0.64
1.17
1.5
3.1
—
—
—
0
0
0
34
0.00
1.16
0.0
1.0
—
0.2
—
0
9
399
4360
0.90
1.13
2.2
2.6
14.9
13.7
umol/l
2.44
369
4065
270
3015
0.89
1.13
2.3
3.4
34.3
42.5
u/ml
0.32
263
2923
47
620
0.75
1.13
5.7
3.0
50.5
38.3
mg/l
0.22
36
506
128
1508
0.84
1.12
2.1
2.5
88.6
128.2
ng/l
2.12
118
1360
47
619
0.76
1.12
5.7
3.0
39.0
40.1
mg/l
0.02
36
501
5
114
0.44
1.12
1.0
1.2
—
—
—
0
0
5
115
0.43
1.11
1.8
5.5
—
—
—
0
0
30
423
0.71
1.10
1.2
1.3
—
—
—
0
0
389
4249
0.90
1.10
1.6
1.6
—
—
—
0
0
29
201
1.45
1.09
1.2
1.2
—
—
—
0
0
7
137
0.51
1.09
1.6
1.1
—
3.1
—
0
8
34
467
0.73
1.08
1.2
1.3
0.6
1.5
nmol/l
0.46
34
449
43
569
0.75
1.07
1.1
1.1
—
—
—
0
0
12
205
0.58
1.06
1.4
1.6
1.1
1.3
promille
—
7
157
130
1520
0.85
1.06
1.1
1.1
—
2.4
—
0
20
35
476
0.73
1.05
6.3
2.9
—
—
—
0
0
37
271
1.37
1.04
1.3
1.3
0.1
0.8
u/ml
1.49
17
108
34
247
1.38
1.01
1.6
2.3
—
—
—
0
0
22
322
0.68
1.01
3.8
3.1
2.6
4.7
nmol/l
1.53
22
302
72
882
0.81
0.98
1.3
1.4
408.1
287.9
ug/g
4.20
33
463
1334
12854
1.06
0.98
7.9
9.2
0.0
0.0
e9/l
1.24
1135
10360
45
344
1.31
0.98
2.4
2.4
—
—
—
0
0
187
2113
0.88
0.98
1.5
1.5
—
—
—
0
0
250
2774
0.89
0.97
1.7
1.8
—
—
—
0
0
12
199
0.60
0.96
1.5
1.6
72.0
71.3
%
0.06
12
184
918
8750
1.07
0.95
5.1
6.1
1.1
1.1
inr
1.39
333
2543
12
198
0.60
0.95
1.5
1.6
432.7
602.9
mu/l
0.49
12
183
274
2484
1.11
0.93
3.5
4.1
—
—
—
0
0
94
1114
0.84
0.92
3.5
2.1
—
—
—
0
0
665
7035
0.93
0.90
2.2
2.3
2.8
2.8
mg/l
0.31
576
6049
1371
14177
0.94
0.90
5.3
5.9
9.7
9.7
umol/l
0.12
1292
13367
43
553
0.77
0.90
2.1
2.1
—
—
—
0
0
158
1789
0.88
0.87
3.3
2.2
67.9
66.9
g/l
1.22
151
1636
70
847
0.82
0.87
1.2
1.6
—
18.3
—
0
28
518
5514
0.93
0.84
1.7
1.6
436.1
23556187.2
pmol/l
3.05
446
4691
107
920
1.17
0.83
1.3
1.4
32.6
30.1
u/l
0.30
94
735
75
625
1.20
0.83
1.1
1.1
—
—
—
0
0
11
178
0.62
0.83
1.2
1.2
—
—
—
0
0
17
249
0.68
0.82
1.1
1.1
285.8
315.6
mg/l
1.09
17
212
117
1344
0.87
0.81
1.6
1.7
—
—
—
0
0
31
232
1.34
0.81
1.1
1.1
19.7
7.8
iu/ml
—
6
69
73
610
1.20
0.79
1.2
1.5
100.0
113.9
u/ml
0.59
17
102
0
24
0.00
0.79
0.0
1.5
—
63.6
—
0
12
34
441
0.77
0.79
1.4
3.1
9.0
8.5
kpa
0.93
29
416
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
0.1
—
0
7
535
5045
1.07
0.77
2.2
2.6
8.5
8.6
e6/l
0.05
459
4350
0
27
0.00
0.77
0.0
1.3
—
143.3
—
0
21
7
125
0.56
0.77
1.9
1.8
0.4
1.1
ug/l
—
7
118
18
257
0.70
0.77
3.6
2.7
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
145.9
—
0
6
9
53
1.70
0.75
1.1
1.1
—
—
—
0
0
28
368
0.76
0.73
1.1
1.5
—
—
—
0
0
15
219
0.68
0.73
1.1
1.1
—
—
—
0
0
220
2410
0.91
0.72
12.6
15.5
1.1
1.2
inr
1.88
40
335
6
109
0.55
0.72
2.5
2.1
—
—
—
0
0
9
57
1.58
0.71
1.2
1.3
—
—
—
0
0
13
194
0.67
0.70
3.8
2.5
10.6
10.4
%
0.06
13
194
704
7367
0.94
0.70
1.9
2.1
123.8
156.1
u/l
1.93
666
6914
127
1126
1.13
0.68
1.3
1.3
—
—
—
0
0
36
452
0.79
0.67
1.2
1.3
1.1
1.3
nmol/l
0.50
31
362
16
226
0.71
0.66
2.5
2.8
737.1
880.7
e6/l
—
7
93
111
978
1.14
0.66
2.2
2.0
4.5
12.6
iu/l
0.51
46
390
224
2058
1.09
0.64
4.1
4.5
0.1
0.0
%
0.18
49
474
714
6839
1.06
0.64
1.8
1.8
0.8
0.9
mg/l
0.90
543
5127
51
612
0.83
0.63
1.1
1.0
0.3
2.8
u/ml
5.54
17
222
33
415
0.79
0.63
3.8
4.6
21.0
57.1
u/ml
—
8
116
130
1450
0.89
0.62
3.1
2.0
—
—
—
0
0
58
684
0.85
0.61
2.0
1.8
40.2
38.6
g/l
1.80
53
602
233
2152
1.09
0.61
4.0
4.4
0.1
0.1
%
0.21
55
553
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
17.1
—
0
12
345
3238
1.07
0.60
1.7
1.8
—
—
—
0
0
21
278
0.75
0.60
1.3
1.2
320.0
144.8
titre
—
5
56
9
141
0.64
0.60
1.4
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
7.2
—
79.6
—
0
14
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
394
4173
0.94
0.59
1.3
1.2
—
—
—
0
0
57
482
1.19
0.59
1.7
2.2
134.9
129.6
g/l
1.30
41
319
37
454
0.81
0.59
1.3
1.3
—
—
—
0
0
29
366
0.79
0.59
1.5
3.1
—
—
—
0
0
10
64
1.56
0.58
1.4
1.2
—
—
—
0
0
224
2070
1.09
0.58
3.8
4.1
0.6
0.8
%
0.47
51
435
74
641
1.16
0.58
1.3
1.2
261.9
294.8
u/ml
0.47
47
431
21
276
0.76
0.58
1.1
1.0
—
—
—
0
0
95
1074
0.88
0.58
1.3
1.3
11.5
13.2
u/l
0.64
81
859
12
173
0.69
0.57
1.2
1.5
139.7
138.2
nmol/l
0.05
12
173
65
559
1.17
0.56
2.3
2.7
13.2
13.3
%
0.39
65
546
37
450
0.82
0.55
2.4
2.3
—
—
—
0
0
31
248
1.25
0.55
1.8
1.5
—
—
—
0
0
77
879
0.87
0.55
1.1
1.1
—
—
—
0
0
221
2381
0.92
0.54
1.2
1.2
—
—
—
0
0
2498
25263
0.96
0.53
12.2
15.5
13.5
13.6
%
1.63
2458
24800
2799
28232
0.95
0.53
5.1
5.3
1.7
2.4
mu/l
3.01
2643
26644
23
294
0.78
0.53
1.4
1.2
—
—
—
0
0
6
39
1.54
0.53
1.5
1.3
—
—
—
0
0
17
226
0.75
0.52
1.9
2.7
569.2
874.6
u/ml
0.75
17
226
9
64
1.41
0.51
1.1
1.1
—
—
—
0
0
251
2682
0.93
0.51
1.4
1.4
—
—
—
0
0
311
3297
0.94
0.50
1.3
1.4
—
—
—
0
0
147
1345
1.10
0.50
1.4
1.3
220.4
235.5
miu/ml
0.23
82
682
62
712
0.87
0.49
1.8
2.2
—
—
—
0
0
25
198
1.26
0.49
2.8
3.2
0.6
0.8
nmol/l
2.73
18
150
97
1080
0.90
0.48
1.2
1.1
14.2
6.1
u/ml
0.67
16
175
7
108
0.65
0.48
1.1
1.6
—
132.6
—
0
13
19
245
0.77
0.48
1.6
2.3
71.0
74.7
%
0.73
19
240
19
245
0.77
0.48
1.1
1.1
—
—
—
0
0
35
420
0.83
0.47
1.8
1.6
—
—
—
0
0
19
244
0.78
0.47
1.6
2.2
17.6
13.6
%
0.87
13
135
7
48
1.46
0.46
2.3
1.9
—
—
—
0
0
24
299
0.80
0.46
2.1
2.6
1.2
1.3
e9/l
0.03
13
177
855
8299
1.04
0.46
2.1
2.6
58.8
55.6
u/l
0.36
789
7599
8
118
0.68
0.45
2.8
2.3
—
—
—
0
0
62
706
0.88
0.45
1.8
1.3
—
—
—
0
0
8
121
0.66
0.45
2.5
1.6
—
—
—
0
0
32
265
1.21
0.44
2.2
2.8
—
—
—
0
0
29
238
1.22
0.44
1.4
1.3
2.2
1.9
mmol/l
0.49
29
219
241
2268
1.07
0.43
4.0
4.4
0.6
1.0
%
1.95
61
602
42
490
0.86
0.43
1.1
1.0
0.0
0.2
u/ml
—
6
88
638
6165
1.04
0.43
1.2
1.3
28.3
30.8
iu/ml
0.19
229
1972
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
27
328
0.82
0.42
1.5
1.8
—
—
—
0
0
8
56
1.43
0.42
1.3
1.4
74.1
92.4
ng/l
—
8
56
5
32
1.56
0.42
1.0
1.0
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
50
574
0.87
0.42
1.1
1.0
1.2
3.6
u/ml
2.22
15
231
26
212
1.23
0.42
1.1
1.1
1.0
1.1
ratio
—
8
75
401
3837
1.05
0.41
1.4
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.7
—
0
10
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
0.2
—
0
9
76
847
0.89
0.41
2.2
2.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
94.9
—
0
16
26
315
0.82
0.40
1.2
1.2
—
—
—
0
0
191
1789
1.07
0.40
1.1
1.1
400.8
195.7
titre
—
6
44
21
260
0.81
0.40
1.3
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
19
237
0.80
0.39
1.2
1.3
—
—
—
0
0
11
148
0.74
0.38
1.0
1.2
244.6
290.7
u/l
0.16
11
134
24
291
0.82
0.38
1.3
1.2
—
38.5
—
0
11
19
236
0.80
0.38
1.9
2.6
668.1
469.7
e6/l
1.31
14
196
15
192
0.78
0.38
1.7
1.5
—
1952.9
—
0
27
18
225
0.80
0.38
1.1
1.1
—
—
—
0
0
147
1368
1.08
0.37
1.1
1.1
—
—
—
0
0
10
136
0.73
0.37
1.5
1.6
—
—
—
0
0
479
4966
0.96
0.37
1.3
1.4
630.3
559.7
titre
0.24
91
1097
69
767
0.90
0.37
1.1
1.1
2.5
4.5
u/ml
1.11
35
393
9
70
1.29
0.36
1.0
1.2
—
—
—
0
0
25
207
1.21
0.36
1.1
1.2
—
—
—
0
0
74
818
0.90
0.36
1.3
1.3
471.1
493.8
mg/l
0.16
74
779
65
723
0.90
0.35
1.1
1.1
1.0
1.2
u/ml
—
9
161
19
234
0.81
0.35
5.3
6.9
—
—
—
0
0
56
498
1.13
0.35
1.5
1.7
—
—
—
0
0
14
179
0.78
0.35
2.0
2.0
29.1
30.1
umol/l
0.20
14
173
5
79
0.63
0.35
1.2
1.2
—
—
—
0
0
22
266
0.83
0.35
1.1
1.1
—
—
—
0
0
6
43
1.40
0.35
5.0
8.4
—
—
—
0
0
1347
13240
1.03
0.35
2.0
2.1
—
—
—
0
0
50
442
1.13
0.35
2.1
3.8
—
—
—
0
0
15
189
0.79
0.34
2.0
2.4
—
—
—
0
0
12
91
1.32
0.33
2.4
2.0
2.8
2.0
ug/l
0.60
12
77
167
1773
0.94
0.33
1.4
1.8
286.7
371.1
mu/l
3.04
148
1564
56
624
0.90
0.32
1.3
1.2
2.6
3.7
u/ml
1.34
32
272
77
843
0.91
0.32
1.1
1.1
2.7
0.8
u/ml
0.63
30
318
191
1808
1.06
0.32
3.0
3.6
—
—
—
0
0
66
727
0.91
0.31
1.8
1.4
2185.8
5903.7
e6/l
0.30
54
563
19
230
0.83
0.31
1.9
2.7
0.3
0.2
e9/l
0.18
14
195
66
726
0.91
0.31
1.7
1.3
102.5
38.7
e6/l
0.36
53
539
46
516
0.89
0.30
1.1
1.1
—
—
—
0
0
23
272
0.84
0.30
1.4
1.3
9.7
10.6
umol/l
0.54
23
259
12
93
1.29
0.30
1.2
1.1
—
—
—
0
0
53
477
1.11
0.29
1.6
3.5
1.9
2.6
mmol/l
1.17
30
317
67
611
1.10
0.29
4.3
3.4
57.7
57.6
%
0.04
67
611
35
398
0.88
0.29
1.9
1.5
—
—
—
0
0
22
259
0.85
0.28
1.2
1.2
—
1.4
—
0
14
17
205
0.83
0.28
2.4
1.8
—
—
—
0
0
9
116
0.78
0.27
1.0
1.1
—
—
—
0
0
82
759
1.08
0.27
3.3
3.3
0.5
0.3
g/l
0.66
40
306
86
926
0.93
0.27
2.7
3.7
—
—
—
0
0
915
9321
0.97
0.26
3.0
3.6
92.7
81.4
e6/l
0.27
618
6041
67
729
0.92
0.26
1.1
1.1
0.9
0.7
u/ml
0.16
25
299
57
625
0.91
0.26
1.1
1.1
3.9
3.1
u/ml
0.30
30
347
202
1929
1.05
0.26
3.1
3.4
1.2
1.2
mmol/l
0.49
173
1673
57
624
0.91
0.26
1.2
1.2
—
—
—
0
0
694
7092
0.97
0.26
4.1
4.3
—
—
—
0
0
65
597
1.09
0.26
3.3
3.3
4.1
4.1
e9/l
0.02
65
597
46
509
0.90
0.25
1.6
3.4
24.8
24.6
mmol/l
0.15
39
456
12
149
0.80
0.25
1.4
1.3
—
—
—
0
0
55
602
0.91
0.25
1.1
1.2
—
—
—
0
0
9
75
1.20
0.25
1.3
1.2
—
—
—
0
0
227
2179
1.04
0.25
1.3
1.3
18.4
38.6
au/ml
—
5
79
62
570
1.09
0.24
1.7
3.4
7.4
7.4
ph
1.12
52
467
26
297
0.87
0.24
1.3
1.5
—
—
—
0
0
26
297
0.87
0.24
1.3
1.5
—
—
—
0
0
26
297
0.87
0.24
1.3
1.5
—
—
—
0
0
26
297
0.87
0.24
1.3
1.5
—
—
—
0
0
256
2654
0.96
0.23
3.2
3.3
4.5
4.5
pmol/l
0.16
232
2357
15
179
0.84
0.23
1.4
1.4
1891.6
4693.8
e6/l
—
10
127
2747
27601
0.97
0.23
3.4
3.6
1.2
1.3
mmol/l
7.44
2590
25870
105
1113
0.94
0.22
1.7
2.7
0.2
0.2
e6/l
0.02
100
1067
122
1287
0.95
0.22
2.4
3.7
5.2
5.1
kpa
0.15
108
1206
48
438
1.10
0.22
1.5
2.6
17.9
16.4
%
2.06
21
233
12
146
0.82
0.22
1.5
1.5
—
—
—
0
0
115
1214
0.95
0.22
1.8
1.9
—
—
—
0
0
53
576
0.92
0.22
2.1
2.6
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
4.8
—
0.8
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
127
1335
0.95
0.21
2.6
2.3
—
—
—
0
0
12
98
1.23
0.21
3.1
2.2
—
—
—
0
0
8
104
0.77
0.21
2.4
2.3
—
—
—
0
0
42
460
0.91
0.20
3.7
3.2
424.4
807.8
u/ml
0.26
37
413
14
166
0.84
0.20
1.4
1.4
50158.8
64702.6
e6/l
—
8
90
138
1445
0.95
0.20
1.9
2.0
4.7
7.1
ug/l
1.29
128
1235
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
6.2
—
361.2
—
0
14
16
136
1.18
0.20
1.0
1.2
—
0.4
—
0
6
121
1270
0.95
0.20
2.4
3.6
7.4
7.4
ph
1.32
17
167
12
144
0.83
0.19
1.1
1.1
1307.1
1527.0
miu/ml
0.31
12
144
429
4390
0.97
0.19
2.7
3.1
398.2
306.8
ng/l
0.26
227
2714
2865
28755
0.98
0.19
3.8
4.1
4.9
4.9
mmol/l
0.59
2724
27170
363
3723
0.97
0.19
1.8
2.0
—
—
—
0
0
365
3559
1.03
0.19
2.0
2.1
28.9
29.3
s
0.92
353
3449
25
222
1.13
0.19
2.0
3.1
21.2
114.1
mg/l
1.85
17
152
37
337
1.10
0.19
1.3
1.2
—
—
—
0
0
240
2475
0.97
0.18
1.4
1.4
—
—
—
0
0
7
60
1.17
0.17
1.7
1.1
—
—
—
0
0
7
60
1.17
0.17
1.7
1.1
—
—
—
0
0
7
60
1.17
0.17
1.7
1.1
—
—
—
0
0
19
216
0.88
0.17
1.1
1.5
13925.4
11271.5
e6/l
0.10
11
150
36
393
0.92
0.17
2.3
1.5
—
—
—
0
0
5
67
0.75
0.17
1.4
1.7
—
—
—
0
0
8
68
1.18
0.16
1.1
5.6
—
—
—
0
0
39
422
0.92
0.16
2.3
1.4
—
—
—
0
0
23
256
0.90
0.16
1.1
1.2
—
—
—
0
0
243
2364
1.03
0.16
2.4
2.3
23.2
24.5
au/ml
0.06
11
182
15
130
1.15
0.15
1.1
1.2
—
—
—
0
0
60
637
0.94
0.15
4.3
5.1
1.2
1.3
mmol/l
0.18
54
560
20
224
0.89
0.15
1.2
1.1
—
—
—
0
0
110
1055
1.04
0.15
1.2
1.2
—
—
—
0
0
23
254
0.90
0.14
1.1
1.1
—
—
—
0
0
166
1610
1.03
0.14
1.0
1.1
—
—
—
0
0
190
1954
0.97
0.13
1.4
1.2
—
—
—
0
0
409
4018
1.02
0.13
1.3
1.2
—
—
—
0
0
223
2287
0.97
0.13
2.1
2.8
3.8
4.1
e9/l
1.81
185
1854
2852
28597
0.98
0.13
3.8
4.0
1.6
1.6
mmol/l
2.10
2694
26949
39
364
1.07
0.13
1.4
1.4
—
—
—
0
0
9
107
0.84
0.13
1.1
1.0
—
—
—
0
0
138
1422
0.97
0.12
1.7
1.9
—
—
—
0
0
17
188
0.90
0.11
1.4
2.3
—
—
—
0
0
54
567
0.95
0.11
1.4
1.7
12397.9
9234.4
e6/l
0.19
43
404
682
6890
0.99
0.10
2.5
2.9
—
—
—
0
0
3105
31002
1.02
0.10
8.9
10.1
25.0
24.6
u/l
0.44
3030
30107
97
939
1.03
0.10
2.2
1.8
1.2
1.5
g/l
2.45
84
808
33
351
0.94
0.10
1.8
2.8
7.6
7.5
mmol/l
0.05
33
345
653
6466
1.01
0.09
3.2
3.4
—
—
—
0
0
54
564
0.96
0.09
1.6
1.4
0.5
0.6
g/l
0.25
45
439
78
807
0.97
0.09
2.8
3.7
24.8
24.7
mmol/l
0.26
71
768
2905
29104
0.99
0.09
4.1
4.4
2.9
2.9
mmol/l
0.48
2729
27368
5
62
0.81
0.08
1.2
1.8
—
—
—
0
0
747
7413
1.01
0.08
2.5
3.1
38.0
62.0
e6/l
0.96
571
5469
26
244
1.07
0.08
2.9
2.7
51.2
57.1
%
0.67
20
164
28
297
0.94
0.08
1.7
1.7
42.4
50.9
%
0.56
21
195
476
4713
1.01
0.07
2.2
2.7
524.3
511.5
mosm/kgh2o
0.49
403
3971
2175
21812
0.99
0.07
3.9
4.1
10.2
11.7
mm/h
8.80
2055
20451
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
41
392
1.05
0.07
1.9
1.4
—
—
—
0
0
147
1498
0.98
0.07
1.2
1.3
2.6
1.7
u/ml
0.20
11
134
56
541
1.04
0.07
1.2
1.2
—
—
—
0
0
8
93
0.86
0.06
3.8
1.3
—
—
—
0
0
8
93
0.86
0.06
3.9
2.2
—
—
—
0
0
38
364
1.04
0.06
1.4
1.3
6.2
6.5
g/l
0.40
29
278
38
364
1.04
0.06
1.4
1.3
3.6
2.7
g/l
1.48
29
278
152
1545
0.98
0.06
1.7
1.8
—
—
—
0
0
35
365
0.96
0.06
1.1
1.0
—
—
—
0
0
38
365
1.04
0.06
1.4
1.3
0.4
0.3
g/l
0.50
30
279
2915
29113
1.01
0.06
10.4
12.9
3.9
3.9
mmol/l
4.76
2838
28315
10
90
1.11
0.05
1.8
1.7
—
—
—
0
0
130
1278
1.02
0.05
1.2
1.2
—
—
—
0
0
2756
27521
1.01
0.05
3.8
4.1
5.6
5.8
mmol/l
12.47
2584
25656
320
3171
1.01
0.05
1.3
1.3
31.5
29.9
iu/l
0.33
280
2685
86
878
0.98
0.05
7.7
8.0
—
—
—
0
0
108
1099
0.98
0.05
1.4
1.4
—
—
—
0
0
40
387
1.03
0.04
3.6
2.7
1.3
1.2
%
0.15
32
314
13
140
0.93
0.04
1.1
1.1
—
—
—
0
0
70
685
1.02
0.04
1.2
1.1
—
—
—
0
0
152
1539
0.99
0.04
1.7
1.8
—
—
—
0
0
28
269
1.04
0.04
1.1
1.0
2.4
1.3
u/ml
—
7
49
103
1014
1.02
0.04
1.3
1.4
6.3
10.3
u/ml
0.59
18
172
12
111
1.08
0.04
1.1
1.1
—
—
—
0
0
70
686
1.02
0.04
1.2
1.1
—
—
—
0
0
150
1517
0.99
0.03
1.6
1.8
—
—
—
0
0
46
472
0.97
0.03
2.5
2.8
32.0
33.1
umol/l
0.14
39
415
398
4002
0.99
0.03
1.3
1.3
—
—
—
0
0
101
996
1.01
0.03
1.3
1.4
16.6
7.9
u/ml
0.33
12
113
2501
24984
1.00
0.03
4.5
4.5
14.5
14.4
pmol/l
0.04
2369
23330
152
1535
0.99
0.03
1.7
1.8
—
—
—
0
0
2905
29029
1.01
0.03
10.4
12.8
139.7
139.6
mmol/l
2.90
2837
28291
16
168
0.95
0.02
1.5
1.6
—
5.5
—
0
23
11
117
0.94
0.01
1.0
1.1
—
—
—
0
0
14
147
0.95
0.01
1.9
2.3
10.4
8.2
%
0.27
14
142
49
482
1.02
0.01
1.6
3.6
—
—
—
0
0
21
203
1.03
0.01
1.2
1.3
—
—
—
0
0
308
3091
1.00
0.01
1.2
1.2
112.7
159.1
iu/ml
1.97
125
1144
668
6667
1.00
0.01
2.2
2.2
1916.4
3274.4
umol/l
0.80
604
5899
11
104
1.06
0.01
1.0
1.1
—
—
—
0
0
11
105
1.05
0.00
1.0
1.0
—
—
—
0
0
11
115
0.96
0.00
1.4
1.5
—
—
—
0
0
11
115
0.96
0.00
1.5
2.3
228.0
162.0
e6/l
—
5
66
13
125
1.04
0.00
1.0
2.2
—
—
—
0
0
29
288
1.01
0.00
1.1
1.2
—
—
—
0
0
17
175
0.97
0.00
1.1
1.2
—
—
—
0
0
44
445
0.99
0.00
1.5
1.6
—
—
—
0
0
234
2345
1.00
0.00
1.3
1.3
197.8
215.6
u/ml
0.10
218
2158
1509
15089
1.00
0.00
3.0
3.1
78.4
82.3
ug/l
0.20
1430
14242
15
151
0.99
0.00
1.1
1.1
—
—
—
0
0
26
259
1.00
0.00
3.2
3.2
—
—
—
0
0
125
1252
1.00
0.00
2.1
2.1
20.7
20.9
s
0.23
104
1090
11
114
0.96
0.00
7.1
2.3
80.5
79.9
ng/l
—
6
45
689
6886
1.00
0.00
2.5
3.0
0.4
0.4
e6/l
0.09
515
4980
28
277
1.01
0.00
1.1
1.0
0.3
0.9
u/ml
—
7
61
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
7
78
0.90
0.00
1.1
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1653.3
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
3.8
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
16
160
1.00
0.00
1.2
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
0.00
1.1
1.2
—
—
—
0
0
6
61
0.98
0.00
1.2
1.3
—
—
—
0
0
6
63
0.95
0.00
1.3
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
63.1
—
0
5

Mortality – FinRegistry

Association

Association between endpoint O15_DELIV_MULTIP and mortality.

Females

Parameter HR [95% CI] p-value
O15_DELIV_MULTIP 0.493 [0.37, 0.66] < 0.001
Birth year 0.998 [0.99, 1.01] 0.635

During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 11349 females with O15_DELIV_MULTIP died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_DELIV_MULTIP.

N-year risk Females Males
1 0.072% No data
5 0.323% No data
10 0.778% No data
15 1.496% No data
20 2.772% No data

Relationships between endpoints

Index endpoint: O15_DELIV_MULTIP – Multiple delivery

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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