Adenocarcinoma and papilloma adenocarcinoma of rectum

C3_RECTUM_ADENO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C20.92&
  • Cancer registry: Topography ICD-O-3 C19|C20
  • Cancer registry: Morphology ICD-O-3 8140
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

3570

4. Check minimum number of events

None

3570

5. Include endpoints

None

3570

6. Filter based on genotype QC (FinnGen only)

3570

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF8

Similar endpoints

List of similar endpoints to Adenocarcinoma and papilloma adenocarcinoma of rectum based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28800 11906 16255
Only index persons 17730 7604 10126
Unadjusted period prevalence (%)
Whole population 0.41 0.34 0.45
Only index persons 0.34 0.28 0.39
Median age at first event (years)
Whole population 68.80 69.27 68.50
Only index persons 68.69 68.89 68.54

-FinnGen-

Key figures

All Female Male
Number of individuals 3570 1326 2244
Unadjusted period prevalence (%) 0.79 0.45 0.99
Median age at first event (years) 67.77 66.20 68.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3307
Matched controls
33067
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B01AB05
ATC
enoxaparin; parenteral
4.4
323.0
1809
7168
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
210.6
323.0
423
23
JGB07
NOMESCO Finland
Laparoscopic partial proctectomy with total excision of mesorectum
947.8
323.0
341
*
TJF80
NOMESCO Finland
Ostomy education
72.6
323.0
436
69
C20
ICD-10 Finland
Malignant neoplasm of rectum
488.4
323.0
702
18
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
+∞
323.0
423
*
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
152.9
323.0
622
50
130
Kela drug reimbursment
Malignant tumour
21.6
323.0
1790
1709
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
11.7
323.0
889
1003
L01BC06
ATC
capecitabine; oral
62.1
323.0
1472
422
WX302
NOMESCO Finland
Thoracal epidural anesthesy
19.8
323.0
1066
777
C20.99
ICD-10 Finland
Malignant tumor of the rectum other or unspecified histology
259.2
323.0
487
22
WF001
NOMESCO Finland
Preoperative radiotherapy
270.7
323.0
770
37
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
330.9
323.0
575
21
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
70.5
323.0
398
64
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
342.7
323.0
469
16
A04AA02
ATC
granisetron; systemic, transdermal
10.6
323.0
810
983
UJF32
NOMESCO Finland
Coloscopy
10.4
323.0
2294
5924
JG1BG
NOMESCO Finland
MRI of rectum
376.1
323.0
533
17
JFF23
NOMESCO Finland
Transversostomy
107.7
323.0
697
82
Z93.3
ICD-10 Finland
Colostomy status
102.1
323.0
435
49
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
474.4
323.0
1532
60
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
4503599627370496.0
323.0
2884
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
2277.2
323.0
2785
73
A03FA01
ATC
metoclopramide; systemic, rectal
7.2
323.0
1671
4111
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
118.3
323.0
387
37
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
21.3
323.0
1615
1416
JN4BD
NOMESCO Finland
Extensive body CT
7.6
323.0
1194
2291
JG1CG
NOMESCO Finland
Extensive MRI of rectum
254.9
323.0
423
19
D75
ICPC
Malignant neoplasm colon/rectum
68.0
315.6
364
60
H02AB02
ATC
dexamethasone; systemic
6.2
296.8
912
1898
UJG02
NOMESCO Finland
Proctoscopy
20.6
284.7
437
243
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
348.0
284.4
284
9
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
13.0
280.6
521
468
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
9.7
260.9
566
686
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
10.9
253.4
514
548
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
15.0
246.8
428
325
WX408
NOMESCO Finland
General anesthesy, balanced
3.6
235.9
1463
5929
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
14.3
232.5
411
325
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
8.1
230.9
564
823
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.4
225.1
1568
6891
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
140.4
221.6
235
18
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
95.4
216.5
239
27
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
16.9
211.4
347
227
WZC30
NOMESCO Finland
Teaching
4.4
211.1
899
2569
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
229.7
210.2
215
10
JN4AD
NOMESCO Finland
Body CT examination
5.4
209.2
710
1594
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
14.2
202.6
358
280
WX600
NOMESCO Finland
Single shot through catheter
28.6
197.3
272
103
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
10.5
194.7
400
428
JGB31
NOMESCO Finland
Laparoscopic and perineal excision of rectum
295.3
192.2
194
7
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
230.0
190.5
195
9
XX3DW
NOMESCO Finland
Time consuming IT work
4.5
183.8
750
2022
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
305.7
171.5
173
6
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
17.7
164.2
264
161
ZX095
NOMESCO Finland
Combined chemoradiotherapy
42.1
160.8
202
51
JFF10
NOMESCO Finland
Loop enterostomy
57.5
160.3
190
35
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
12.5
158.1
295
257
TPH07
NOMESCO Finland
Cathetrisation of artery
4.0
154.5
722
2172
ZXE20
NOMESCO Finland
More than three and less than five hours
3.4
141.6
833
2998
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.4
139.4
352
522
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
17.7
136.0
218
131
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.4
128.5
364
631
SPAT1125
SPAT
Stoma care and guidance
11.4
128.4
250
236
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
7.0
127.5
335
524
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
65.8
125.1
145
23
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
6.0
123.4
364
664
WX402
NOMESCO Finland
General anaesthesia
3.1
118.8
771
2932
Z93
ICD-10 Finland
Artificial opening status
95.8
116.9
129
14
JN4CD
NOMESCO Finland
Very extensive body CT
5.6
112.2
352
690
ZX070
NOMESCO Finland
Intensity modified radiotherapy
8.8
109.9
247
302
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
10.1
109.2
225
236
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
5.0
108.9
380
839
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.7
107.8
398
933
JGB37
NOMESCO Finland
Laparoscopic wide excision of rectum
263.1
100.3
102
*
B01AB10
ATC
tinzaparin; parenteral
3.9
97.0
435
1222
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
10.7
96.2
192
189
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
8.5
95.4
218
273
SPAT1262
SPAT
Handing over of treatment supplies
2.5
94.4
895
4219
N02AA05
ATC
oxycodone; systemic
2.7
94.3
775
3367
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.9
93.4
246
382
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.4
93.3
369
921
D18
ICPC
Change in faeces/bowel movements
8.8
89.5
199
238
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.1
87.5
559
2055
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
8.6
86.1
194
237
ZX090
NOMESCO Finland
Other technic of radiotherapy
6.2
85.3
242
415
JGB36
NOMESCO Finland
Wide excision of rectum
180.6
84.6
88
5
ZXC96
NOMESCO Finland
Robot assisted procedure
6.3
84.4
237
401
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
12.9
83.7
152
123
JF2AB
NOMESCO Finland
Colongraphy with X-ray
45.7
82.9
102
23
JGB01
NOMESCO Finland
Laparoscopic partial proctectomy and colorectal or coloanal anastomosis
148.8
82.4
87
6
1541A
ICD-9 Finland
Malignant neoplasm of rectum, rectosigmoid junction and anus, Rectum[NEOPLASMA MALIG RECTI,INVASIIVINEN KARSINOOMA]
807.3
80.8
79
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.5
79.0
298
706
Z43.3
ICD-10 Finland
Attention to colostomy
48.8
78.2
95
20
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
9.0
77.1
169
197
TQW40
NOMESCO Finland
Remowal of suture of skin
3.6
76.8
376
1127
369
Kela drug reimbursment
Regorafenib
69.4
76.7
88
13
A04AA01
ATC
ondansetron; systemic, rectal
3.7
76.4
364
1067
YL1CD
NOMESCO Finland
Very extensive CT examination of pelvis for dose design of radiotherapy
78.4
74.4
84
11
L01BC59
ATC
trifluridine, combinations; systemic
59.5
74.1
87
15
JGB10
NOMESCO Finland
Partial proctectomy and end colostomy
59.5
74.1
87
15
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
21.0
73.4
110
54
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.8
73.4
263
590
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
73.3
502
1917
Z51.5
ICD-10 Finland
Palliative care
3.4
71.1
384
1241
1506
Kela drug reimbursment
The combination of trifluridine and tipiracil
53.1
69.4
83
16
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
68.6
420
1485
3018
Kela drug reimbursment
The combination of trifluridine and tipiracil
52.5
68.4
82
16
D99
ICPC
Disease digestive system other
11.5
67.1
128
115
ZX120
NOMESCO Finland
Intravenous
2.9
65.6
448
1699
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
20.3
64.2
97
49
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.6
63.3
142
172
JG1DG
NOMESCO Finland
Very extensive MRI of rectum
136.7
63.1
67
5
176
Kela drug reimbursment
Regorafenib
51.1
62.4
75
15
N02BE01
ATC
paracetamol; systemic, rectal
2.2
62.0
2840
24226
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
61.9
338
1097
JG1CM
NOMESCO Finland
Extensive MRI of rectum (more than 1.5 T)
598.4
59.9
59
*
JAH00
NOMESCO Finland
Laparotomy
5.1
59.3
197
406
JGB20
NOMESCO Finland
Partial rectosigmoidectomy and abdominoperineal pull-through anastomosis
296.9
57.4
58
*
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
28.5
57.2
78
28
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
57.0
830
4615
JJB10
NOMESCO Finland
Atypcal resection of liver
42.0
56.2
70
17
Z43.2
ICD-10 Finland
Attention to ileostomy
38.1
55.8
71
19
1XC07
NOMESCO Finland
NA
37.6
54.9
70
19
JFF27
NOMESCO Finland
Laparoscopic sigmoidostomy
70.0
54.3
62
9
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
54.1
288
914
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
5.2
52.8
172
347
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
14.3
51.7
89
64
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
6.8
51.4
134
204
R4110
NOMESCO Finland
Physiotherapy
1.9
51.4
971
5927
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
15.0
50.5
85
58
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
6.5
50.2
135
215
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.0
49.9
212
558
JFB00
NOMESCO Finland
Partial resection of small intestine
6.6
48.4
128
199
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
10.8
46.6
91
86
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.7
45.9
213
605
Z93.2
ICD-10 Finland
Ileostomy status
22.4
45.3
66
30
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
20.4
45.3
68
34
JGA73
NOMESCO Finland
Transanal excision of lesion of rectum
33.3
45.1
59
18
JFF24
NOMESCO Finland
Laparoscopic transversostomy
99.4
44.9
49
5
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.0
44.6
271
942
WF004
NOMESCO Finland
Palliative radiotherapy
5.2
44.5
143
284
E0000UV
ATC
NA
1.7
43.8
1218
8335
K56.7
ICD-10 Finland
Ileus, unspecified
5.6
43.7
132
244
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.4
43.7
221
673
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
42.1
1258
8765
L01XE21
ATC
[U] regorafenib; oral
69.4
42.1
48
7
C21.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of rectum, anus and anal canal
114.0
41.8
45
*
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
5.5
41.7
128
241
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
12.5
41.4
75
61
JN2BD
NOMESCO Finland
Extensive CT exmaniation of lower part of abdomen
26.3
41.1
57
22
B01AB04
ATC
dalteparin; parenteral
3.1
40.7
240
817
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
9.7
40.6
84
89
6434
FHL
Anterior resection
65.1
39.1
45
7
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
36.2
39.1
50
14
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
14.4
38.2
65
46
6435
FHL
Abdominoperineal resection and colostomy
197.1
37.9
39
*
WW500
NOMESCO Finland
Blood transfusion
3.3
37.3
202
647
JFF26
NOMESCO Finland
Sigmoidostomy
34.7
37.2
48
14
A04AD12
ATC
aprepitant; systemic
5.3
37.1
117
228
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.6
36.7
133
301
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
13.6
36.7
64
48
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
5.4
36.0
112
215
XJG12
NOMESCO Finland
Transrectal endoscopic ultrasonography
44.5
35.9
44
10
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.8
35.4
159
439
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
20.3
34.8
52
26
C21.0
ICD-10 Finland
Malignant neoplasm: Anus, unspecified
31.1
34.8
46
15
A79
ICPC
Malignancy NOS
6.0
34.1
96
163
Z51.0
ICD-10 Finland
Radiotherapy session
5.9
34.1
97
167
JG001
NOMESCO Finland
Preopertaive radiotherapy of rectum
340.5
34.0
34
*
N03AX16
ATC
pregabalin; oral
1.8
33.9
775
4920
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
10.5
33.6
66
64
WX704
NOMESCO Finland
Intubation
2.5
33.5
273
1132
D01.2
ICD-10 Finland
Carcinoma in situ: Rectum
+∞
33.4
32
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
7.3
33.2
81
113
A04AA55
ATC
palonosetron, combinations; systemic
4.1
33.2
133
332
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
32.7
811
5268
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
37.7
32.4
41
11
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
20.3
32.2
48
24
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
32.0
144
399
JGB11
NOMESCO Finland
Laparoscopic partial proctectomy and end colostomy
319.9
31.9
32
*
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.3
31.1
165
521
WF002
NOMESCO Finland
Radical radiotherapy
2.5
30.0
247
1030
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.6
29.9
234
948
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.1
29.8
119
297
C18.90
ICD-10 Finland
Malignant tumor in unspecified location in the colon without histology
16.2
29.8
48
30
JJB30
NOMESCO Finland
Excision of two segments of liver
37.4
29.3
37
10
C18.7
ICD-10 Finland
Malignant neoplasm: Sigmoid colon
10.7
28.9
56
53
JFB60
NOMESCO Finland
Resection of sigmoid colon with end colostomy
8.9
28.9
62
71
WF003
NOMESCO Finland
Adjuvant radiotherapy
3.2
28.4
158
517
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
28.2
435
2402
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
28.1
330
1633
V03AF03
ATC
calcium folinate; systemic
23.2
27.4
39
17
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.4
27.4
139
425
K92.1
ICD-10 Finland
Melaena
2.4
27.3
239
1028
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.9
27.1
116
308
JAG41
NOMESCO Finland
Repair of stomal hernia, laparoscopic
75.7
26.8
30
*
D16
ICPC
Rectal bleeding
4.2
26.7
105
259
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
10.8
26.5
51
48
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
3.5
26.4
128
378
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
21.3
26.0
38
18
LEC00
NOMESCO Finland
Partial excision of vagina
60.5
26.0
30
5
JN2BG
NOMESCO Finland
MRI examination of lower part of abdoment with high intensity magnet
10.1
25.7
51
51
L01BC53
ATC
tegafur, combinations; systemic
25.2
25.2
35
14
TJG20
NOMESCO Finland
Transanal irrigation
22.7
25.2
36
16
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
4.6
25.1
88
194
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.8
24.8
108
292
C209
ICD-10 Finland
NA
70.4
24.8
28
*
JAH01
NOMESCO Finland
Laparoscopy
3.0
24.8
145
492
15411
ICD-8 Finland
Malignant neoplasm of rectum and rectosigmoid junction, Rectum
251.9
24.7
25
*
XX1AD
NOMESCO Finland
Other CT-examination
8.8
24.2
52
60
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.7
24.2
62
94
R4190
NOMESCO Finland
Nutritional therapy
3.3
24.2
125
388
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
4.1
23.9
94
232
S18
ICPC
Laceration/cut
1.5
23.5
1342
10492
JJB71
NOMESCO Finland
Laparoscopic resection of liver
33.6
23.3
30
9
ZXD05
NOMESCO Finland
Urgent procedure
1.5
23.2
970
7093
JG1BM
NOMESCO Finland
MRI of rectum (more than 1.5 T)
+∞
22.9
22
*
1541X
ICD-9 Finland
Malignant neoplasm of rectum, rectosigmoid junction and anus, Rectum[NEOPLASMA MALIG RECTI,EI HISTOLOGISTA VAHVISTUSTA]
+∞
22.9
22
*
JN3GE
NOMESCO Finland
Intraoperative ultrasound examination of abdomen
32.5
22.4
29
9
Z3231
NOMESCO Finland
Registered nurse
1.5
21.9
865
6227
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
7.4
21.9
52
71
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
12.3
21.8
39
32
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
25.2
21.7
30
12
JFB54
NOMESCO Finland
Laparoscopic resection of sigmoid colon with partial proctectomy
18.5
21.7
33
18
Z31.5
ICD-10 Finland
Genetic counselling
3.2
21.7
119
387
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
14.5
21.6
36
25
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
8.0
21.2
48
61
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.4
21.0
187
810
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
4.4
21.0
76
174
JFB53
NOMESCO Finland
Resection of sigmoid colon with partial proctectomy
28.2
20.9
28
10
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
8.6
20.8
45
53
D28
ICPC
Limited function/disability (D)
14.1
20.8
35
25
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
4.9
20.5
67
138
JFF30
NOMESCO Finland
Other colostomy
25.6
20.4
28
11
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
19.9
1180
9207
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.4
19.8
72
166
ZX080
NOMESCO Finland
Image guided radiotherapy
3.5
19.5
92
267
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
19.5
229
1127
C18.9
ICD-10 Finland
Malignant neoplasm: Colon, unspecified
21.7
19.5
28
13
R03AC02
ATC
salbutamol; inhalant
0.7
19.4
920
11798
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.6
19.2
86
240
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
16.8
19.1
30
18
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
19.1
264
1393
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.0
19.0
111
377
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
4.9
18.9
62
129
JN2DM
NOMESCO Finland
Lower part of abdomen very extensive MRI examination with Tesla magnet
9.2
18.8
39
43
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.1
18.8
73
180
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
18.4
557
3745
JJB20
NOMESCO Finland
Excision of single segment of liver
30.2
18.3
24
8
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.1
18.3
104
345
P01AB01
ATC
metronidazole; oral, rectal
1.4
18.2
1063
8236
JHA00
NOMESCO Finland
Anal or perianal incision
4.8
18.0
60
127
JAG43
NOMESCO Finland
Repair of stomal hernia with mesh
52.8
17.9
21
*
JA3CT
NOMESCO Finland
Cathetrisation of abdominal cavity with CT guidance
26.8
17.8
24
9
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.3
17.8
171
770
NET99
NOMESCO Finland
Other operation on pelvis
66.9
17.7
20
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
17.7
160
700
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.4
17.7
87
262
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
17.7
572
3904
TPX15
NOMESCO Finland
Removal of vascular injection port
8.5
17.6
38
45
XX4AT
NOMESCO Finland
Other canalization with ultrasound guidance
10.4
17.6
34
33
K43.5
ICD-10 Finland
Parastomal hernia without obstruction or gangrene
36.9
17.6
22
6
JEA00
NOMESCO Finland
Appendectomy
2.2
17.5
183
860
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.4
17.5
150
639
D17
ICPC
Incontinence of bowel
5.8
17.3
49
86
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.7
17.3
76
209
R19.4
ICD-10 Finland
Change in bowel habit
3.1
17.0
93
304
D29
ICPC
Digestive symptom/complaint other
3.6
16.9
77
219
Z71.8
ICD-10 Finland
Other specified counselling
1.5
16.8
606
4237
1XC08
NOMESCO Finland
NA
63.6
16.7
19
*
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
4.6
16.5
57
126
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.1
16.5
196
974
UJF34
NOMESCO Finland
Left colonoscopy
6.0
16.4
45
76
WX110
NOMESCO Finland
Local anesthesy
1.4
16.4
1862
16069
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.2
16.4
175
829
JJ6LT
NOMESCO Finland
Coagulation of focal hepatic lesion under ultrasound guidance
20.1
16.4
24
12
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
5.1
16.3
51
101
JJB60
NOMESCO Finland
Other excsion of three or more segments of liver
40.3
16.3
20
5
K61.1
ICD-10 Finland
Rectal abscess
12.2
16.3
29
24
R50.9
ICD-10 Finland
Fever, unspecified
1.6
16.0
416
2679
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
16.0
1416
11720
K45.0
ICD-10 Finland
Other specified abdominal hernia with obstruction, without gangrene
21.0
16.0
23
11
TJX00
NOMESCO Finland
Punkture or biopsy in gastrointestinal endoscopy
21.0
16.0
23
11
A06AD11
ATC
lactulose; oral
1.6
15.9
508
3447
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
15.8
242
1323
KBV15
NOMESCO Finland
Cystoscopic change of ureteral stent
6.6
15.8
40
61
Y83.2
ICD-10 Finland
Surgical operation with anastomosis, bypass or graft as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
11.2
15.7
29
26
JFB20
NOMESCO Finland
Ileocaecal resection
7.6
15.6
36
48
JJB40
NOMESCO Finland
Excision of segments II, III and IV of liver
38.2
15.4
19
5
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.5
15.0
69
198
SPAT1153
SPAT
Removal of sutures
1.4
14.9
997
7849
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
4.5
14.8
52
117
J01MA12
ATC
levofloxacin; systemic
1.5
14.7
601
4307
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
25.1
14.7
20
8
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
9.7
14.7
29
30
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
21.1
14.6
21
10
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
3.7
14.3
61
165
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
4.9
14.1
45
92
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
14.0
256
1489
LEE10
NOMESCO Finland
Repair of vagina using graft or flap
75.4
13.6
15
*
JFG30
NOMESCO Finland
Closure of colostomy with resection of exteriorised loop
14.7
13.6
22
15
JKA20
NOMESCO Finland
Cholecystectomy
2.4
13.5
116
497
JAD10
NOMESCO Finland
Repair of incisional hernia
4.6
13.3
45
98
ZX121
NOMESCO Finland
Central venous catheter
7.7
13.3
30
39
K56.0
ICD-10 Finland
Paralytic ileus
4.1
13.3
51
126
C18.91
ICD-10 Finland
Malignant tumor of unspecified location in colon invasive carcinoma
13.8
13.2
22
16
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
4.9
12.9
41
84
ZXE00
NOMESCO Finland
One hour or less
1.3
12.9
1120
9149
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
3.6
12.8
56
156
D77
ICPC
Malignant digestive neopl other/NOS
6.6
12.8
32
49
TJX90
NOMESCO Finland
Other minor procedure in gastroenterological surgery
14.1
12.7
21
15
C18
ICD-10 Finland
Malignant neoplasm of colon
14.1
12.7
21
15
WX882
NOMESCO Finland
High dependency care
2.4
12.7
104
435
K43.3
ICD-10 Finland
Parastomal hernia with obstruction, without gangrene
+∞
12.5
12
*
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
2.7
12.5
83
310
R33
ICD-10 Finland
Retention of urine
1.6
12.4
312
1986
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
12.3
472
3325
A02BC02
ATC
pantoprazole; systemic
1.3
12.3
1934
17157
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.3
12.3
116
522
WGA11
NOMESCO Finland
Planning of pain management
14.4
12.2
20
14
A06AH03
ATC
naloxegol; oral
3.6
12.2
54
152
K46.9
ICD-10 Finland
Unspecified abdominal hernia without obstruction or gangrene
5.8
12.1
33
57
KCC10
NOMESCO Finland
Cystoprostatectomy
5.6
12.1
34
61
JFB46
NOMESCO Finland
Resection of sigmoid colon
3.6
11.9
53
150
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
4.4
11.8
41
93
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
11.7
244
1474
JGA98
NOMESCO Finland
Other transluminal endoscopic local operation on rectum
16.4
11.6
18
11
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
4.3
11.6
42
99
1540A
ICD-9 Finland
Malignant neoplasm of rectum, rectosigmoid junction and anus, Rectosigmoid junction[NEOPL MALIG JUNCT RECTOSIGM,INVASIIVINEN KARSINOOMA]
+∞
11.5
11
*
178
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
13.6
11.4
19
14
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.1
11.4
61
199
K43.2
ICD-10 Finland
Incisional hernia without obstruction or gangrene
8.9
11.2
23
26
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
3.2
11.2
57
180
LCD00
NOMESCO Finland
Hysterectomy
2.3
11.2
104
467
R01AD09
ATC
mometasone; nasal
0.7
11.1
696
8737
JGA75
NOMESCO Finland
Endoscopic microsurgical excision of lesion of rectum
20.1
11.1
16
8
A28
ICPC
Limited function/disability NOS
1.4
11.1
502
3658
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.7
11.0
509
6683
G47.3
ICD-10 Finland
Sleep apnoea
0.7
11.0
325
4603
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
3.7
10.9
47
130
G04CA02
ATC
tamsulosin; oral
1.3
10.9
918
7423
JAG00
NOMESCO Finland
Repair of other hernia
11.9
10.8
19
16
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
10.6
10.7
20
19
JAG96
NOMESCO Finland
Other reconstruction of abdominal wall
10.6
10.7
20
19
GDB10
NOMESCO Finland
Wedge resection of lung
8.8
10.7
22
25
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
2.9
10.7
63
220
WX002
NOMESCO Finland
Sedation and analgesia
1.4
10.6
577
4342
JF2CG
NOMESCO Finland
Extensive MRI of colon
60.2
10.6
12
*
Z93.4
ICD-10 Finland
Other artificial openings of gastrointestinal tract status
60.2
10.6
12
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.7
10.6
456
6061
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
5.1
10.6
32
63
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
6.0
10.6
28
47
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
10.5
438
3139
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
10.5
391
2737
KBV00
NOMESCO Finland
Insertion of stent into ureter
5.0
10.4
32
64
L03AA02
ATC
filgrastim; parenteral
2.4
10.3
84
353
JFB30
NOMESCO Finland
Right hemicolectomy
2.9
10.3
60
207
L01BC04
ATC
carmofur; oral
32.6
10.3
13
*
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
4.4
10.3
36
83
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
6.0
10.3
27
45
KBH20
NOMESCO Finland
Replantation of ureter
10.6
10.3
19
18
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
10.0
872
7070
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
14.6
10.0
16
11
UJH02
NOMESCO Finland
Anoscopy
2.0
10.0
123
622
JGA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in rectum
12.2
9.8
17
14
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
3.5
9.8
44
127
JGA96
NOMESCO Finland
Other proctotomy or local operation on rectum
20.1
9.8
14
7
M01AE02
ATC
naproxen; oral, rectal
0.8
9.7
1097
12812
J01MA02
ATC
ciprofloxacin; systemic
1.3
9.7
1169
9901
M25.5
ICD-10 Finland
Pain in joint
0.7
9.6
393
5278
Z08.9
ICD-10 Finland
Follow-up examination after unspecified treatment for malignant neoplasm
5.3
9.6
28
53
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
5.3
9.6
28
53
UJF32
SPAT
NA
3.0
9.6
55
187
R03DC03
ATC
montelukast; oral
0.6
9.5
156
2499
JJA43
NOMESCO Finland
Destruction of lesion of liver
100.3
9.4
10
*
JJ7LT
NOMESCO Finland
Coagulation of focal hepatic lesion under CT guidance
30.1
9.4
12
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.7
9.4
519
6650
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
3.4
9.3
43
127
JFA42
NOMESCO Finland
Endoscopic injection in colon
5.6
9.3
26
47
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
9.3
165
953
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
3.8
9.3
37
97
JFA70
NOMESCO Finland
Suture of small intestine
8.7
9.3
19
22
JN2AD
NOMESCO Finland
CT examination of lower part of abdomen
10.7
9.3
17
16
H03AA01
ATC
levothyroxine sodium; systemic
0.7
9.2
317
4380
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.7
9.1
376
5045
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.0
9.1
110
553
R11
ICD-10 Finland
Nausea and vomiting
1.7
9.1
202
1248
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
9.0
444
3277
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
3.4
8.9
41
121
WX892
NOMESCO Finland
Monitored bed care
1.6
8.9
234
1511
JHA10
NOMESCO Finland
Biopsy of anal canal
18.6
8.9
13
7
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
0.6
8.9
122
2040
Z85.0
ICD-10 Finland
Personal history of malignant neoplasm of digestive organs
8.0
8.8
19
24
SPAT1131
SPAT
Colonoscopy
2.0
8.8
106
534
R19.5
ICD-10 Finland
Other faecal abnormalities
3.0
8.8
47
156
A07DA03
ATC
loperamide; oral
1.9
8.8
118
619
C21.1
ICD-10 Finland
Malignant neoplasm: Anal canal
9.5
8.8
17
18
R07.4
ICD-10 Finland
Chest pain, unspecified
0.7
8.8
504
6433
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.7
8.7
537
6791
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
8.7
116
608
N32.1
ICD-10 Finland
Vesicointestinal fistula
7.2
8.7
20
28
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.6
8.7
222
1423
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.6
8.5
197
1231
L01EX05
ATC
regorafenib; oral
20.1
8.5
12
6
GDB20
NOMESCO Finland
Segmental resection of lung
20.1
8.5
12
6
R05FB02
ATC
cough suppressants and expectorants
0.8
8.4
760
9158
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
2.3
8.4
77
345
R03BA05
ATC
fluticasone; inhalant
0.7
8.4
236
3382
JGA58
NOMESCO Finland
Endoscopic insertion of prosthetic tube into rectum
90.2
8.4
9
*
M01AH05
ATC
etoricoxib; oral
0.8
8.4
1153
13249
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
8.4
73
318
JGB97
NOMESCO Finland
Other laparoscopic proctectomy or excision of rectum
+∞
8.3
8
*
R06.0
ICD-10 Finland
Dyspnoea
0.7
8.3
440
5688
JFA55
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in colon
5.2
8.3
24
46
K60.4
ICD-10 Finland
Rectal fistula
10.8
8.3
15
14
Z08.8
ICD-10 Finland
Follow-up examination after other treatment for malignant neoplasm
5.5
8.3
23
42
JFB63
NOMESCO Finland
Other resection of colon with proximal colostomy and closure of distal stump
14.5
8.2
13
9
M03BC51
ATC
orphenadrine, combinations; systemic
0.7
8.2
418
5428
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.8
8.2
125
688
M01AC06
ATC
meloxicam; systemic, rectal
0.8
8.1
663
8087
Z93.8
ICD-10 Finland
Other artificial opening status
17.2
8.1
12
7
JJA20
NOMESCO Finland
Open biopsy of liver
6.8
8.0
19
28
R15
ICD-10 Finland
Faecal incontinence
2.2
8.0
74
333
JFK00
NOMESCO Finland
Division of adhesive band in intestinal obstruction
6.3
8.0
20
32
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
6.3
8.0
20
32
Z98.8
ICD-10 Finland
Other specified postsurgical states
3.1
8.0
41
133
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.3
8.0
68
295
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.6
8.0
186
1167
M17.1
ICD-10 Finland
Other primary gonarthrosis
0.7
7.9
372
4897
H02AB04
ATC
methylprednisolone; systemic
0.7
7.9
194
2857
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
3.3
7.9
37
112
JFB50
NOMESCO Finland
Other resection of colon
6.6
7.9
19
29
J01FA06
ATC
roxithromycin; oral
0.8
7.8
759
9086
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
2.4
7.8
61
253
J01FA10
ATC
azithromycin; systemic
0.8
7.8
1001
11608
A02BC03
ATC
lansoprazole; oral
0.8
7.7
562
6966
ZZR00
NOMESCO Finland
Flap of skin
2.1
7.6
81
387
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.7
7.6
432
5532
K91.3
ICD-10 Finland
Postoperative intestinal obstruction
11.9
7.6
13
11
JFC20
NOMESCO Finland
Other enterocolostomy
25.0
7.6
10
*
JFB43
NOMESCO Finland
Left hemicolectomy
3.6
7.5
32
90
A89
ICPC
Effect prosthetic device
8.9
7.5
15
17
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
0.6
7.5
83
1465
J01AA02
ATC
doxycycline; systemic
0.8
7.5
1952
21120
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
0.8
7.4
472
5956
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
7.6
7.4
16
21
D07AA02
ATC
hydrocortisone; topical
1.4
7.4
301
2146
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
3.3
7.3
35
108
C21.2
ICD-10 Finland
Malignant neoplasm: Cloacogenic zone
+∞
7.3
7
*
M03BX02
ATC
tizanidine; oral
0.8
7.3
1216
13762
JFA86
NOMESCO Finland
Closure of fistula of colon
15.8
7.2
11
7
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
5.8
7.2
19
33
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
7.2
356
2630
N02AX02
ATC
tramadol; systemic, rectal
1.2
7.2
1218
10634
K59.1
ICD-10 Finland
Functional diarrhoea
1.7
7.1
127
738
RD211
NOMESCO Finland
NA
1.8
7.1
112
626
JFF13
NOMESCO Finland
Terminal enterostomy
5.6
7.0
19
34
J01FA09
ATC
clarithromycin; systemic
0.8
7.0
480
6009
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.9
7.0
40
138
K65.0
ICD-10 Finland
Acute peritonitis
2.7
6.9
45
170
YX9CD
NOMESCO Finland
Other very extensive CT eamination for dose design of radiotherapy
7.5
6.9
15
20
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
13.8
6.9
11
8
SPAT1078
SPAT
Removal of central venous or arterial cannula
10.9
6.8
12
11
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
22.5
6.7
9
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.6
6.6
78
1355
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
3.0
6.5
34
113
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
3.0
6.5
34
113
N06CA01
ATC
amitriptyline and psycholeptics; systemic
0.6
6.5
117
1835
C01DA14
ATC
isosorbide mononitrate; oral
0.7
6.5
351
4536
J01.0
ICD-10 Finland
Acute maxillary sinusitis
0.7
6.5
227
3132
M02AA07
ATC
piroxicam; topical
0.8
6.5
771
9055
AN1
HP
Coronary angiography
0.7
6.4
230
3163
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.4
290
2107
JFF31
NOMESCO Finland
Other laparoscopic colostomy
69.9
6.4
7
*
M01AB05
ATC
diclofenac; systemic, rectal
0.8
6.4
1494
16463
UKB02
NOMESCO Finland
Retrograde ureteroscopy
2.8
6.4
38
137
G44.2
ICD-10 Finland
Tension-type headache
0.6
6.4
126
1933
WC125
NOMESCO Finland
Demanding cytostatic therapy of local tumor recidive
6.5
6.3
15
23
R02
ICPC
Shortness of breath/dyspnoea
0.7
6.3
157
2301
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.0
6.3
80
414
JWC00
NOMESCO Finland
Reoperation for deep infection in gastroenterological surgery
11.0
6.3
11
10
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
2.4
6.3
51
218
JAG46
NOMESCO Finland
Repair of recurrent stomal hernia, laparoscopic
+∞
6.2
6
*
1541B
ICD-9 Finland
Malignant neoplasm of rectum, rectosigmoid junction and anus, Rectum[NEOPLASMA MALIG RECTI,KARSINOOMA ADENOOMASSA]
+∞
6.2
6
*
JFW98
NOMESCO Finland
Other transluminal endoscopic operation on intestine
26.7
6.2
8
*
KC1GD
NOMESCO Finland
CT cystography of bladder
26.7
6.2
8
*
R03BA02
ATC
budesonide; inhalant
0.7
6.2
236
3212
H02AB07
ATC
prednisone; oral
0.7
6.2
210
2915
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
3.4
6.2
27
79
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
6.2
*
257
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
3.6
6.2
25
69
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
0.3
6.1
12
401
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
5.3
6.1
17
32
XF612
NOMESCO Finland
Measurement of central venous pressure
5.3
6.1
17
32
K62.1
ICD-10 Finland
Rectal polyp
2.7
6.1
38
142
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
3.0
6.1
32
108
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
0.7
6.1
152
2225
K61.0
ICD-10 Finland
Anal abscess
2.7
6.1
38
143
JFA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in colon
8.6
6.0
12
14
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
6.7
6.0
14
21
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
2.8
6.0
35
124
N06AB04
ATC
citalopram; systemic
0.7
6.0
325
4200

Mortality – FinRegistry

Association

Association between endpoint C3_RECTUM_ADENO and mortality.

Females

Parameter HR [95% CI] p-value
C3_RECTUM_ADENO 2.736 [2.47, 3.04] < 0.001
Birth year 0.994 [0.99, 1.0] 0.147

During the follow-up period (1.1.1998 — 31.12.2019), 3757 out of 7528 females with C3_RECTUM_ADENO died.

Males

Parameter HR [95% CI] p-value
C3_RECTUM_ADENO 2.683 [2.41, 2.99] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 5642 out of 10593 males with C3_RECTUM_ADENO died.

Mortality risk

Mortality risk for people of age

years, who have C3_RECTUM_ADENO.

N-year risk Females Males
1 0.436% 0.519%
5 1.75% 2.748%
10 4.207% 7.496%
15 8.114% 13.755%
20 13.161% 22.668%

Relationships between endpoints

Index endpoint: C3_RECTUM_ADENO – Adenocarcinoma and papilloma adenocarcinoma of rectum

GWS hits: 8

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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