Temporal arteritis

M13_TEMPARTERIT

temporal arteritis: Giant cell arteritis (GCA) is a large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M31.5
  • Cause of death: ICD-10 M31.5

2 out of 7 registries used, show all original rules.

1348

4. Check minimum number of events

None

1348

5. Include endpoints

None

1348

6. Filter based on genotype QC (FinnGen only)

1321

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M31
Name in latin
Arteritis gigantocellularis cum polymyalgia reumatica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7500 5041 2416
Only index persons 6755 4573 2182
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.07
Only index persons 0.14 0.17 0.08
Median age at first event (years)
Whole population 72.49 72.98 71.41
Only index persons 71.88 72.38 70.83

-FinnGen-

Key figures

All Female Male
Number of individuals 1321 815 506
Unadjusted period prevalence (%) 0.27 0.29 0.23
Median age at first event (years) 70.31 69.98 70.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1348
Matched controls
13480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AX03
ATC
methotrexate; systemic
10.9
307.7
464
622
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
4503599627370496.0
307.7
1346
5
H02AB06
ATC
prednisolone; systemic
22.1
307.7
1247
4833
PAW37
NOMESCO Finland
Biopsy of temporal artery
1315.5
307.7
550
7
M35.3
ICD-10 Finland
Polymyalgia rheumatica
67.0
307.7
527
128
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
8.7
290.9
466
770
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.4
220.4
995
4131
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.9
220.4
285
357
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
16.2
215.8
193
138
M05BA04
ATC
alendronic acid; oral
6.4
207.4
445
966
M31.6
ICD-10 Finland
Other giant cell arteritis
1116.4
201.4
192
*
R51.80
ICD-10 Finland
Headache
5.1
151.4
413
1080
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.0
125.4
254
506
I77.6
ICD-10 Finland
Arteritis, unspecified
197.4
106.1
109
6
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
93.9
89
*
A02BC02
ATC
pantoprazole; systemic
4.7
90.0
1173
7938
L88
ICPC
Rheumatoid/seropositive arthritis
7.0
87.6
142
224
R50.9
ICD-10 Finland
Fever, unspecified
3.6
85.2
349
1182
L04AX01
ATC
azathioprine; systemic
7.6
84.2
125
179
H02AB07
ATC
prednisone; oral
3.3
66.9
319
1172
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
30.2
61.8
41
14
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.3
61.6
172
439
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
60.7
858
5428
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.1
52.9
95
165
H53.1
ICD-10 Finland
Subjective visual disturbances
3.9
50.6
162
455
TPX00
NOMESCO Finland
Biopsy of artery or vein
137.8
50.2
53
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
49.6
271
1062
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.2
47.4
72
105
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
46.4
351
1620
N01
ICPC
Headache
3.4
45.8
187
616
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
15.6
43.5
38
25
G44.2
ICD-10 Finland
Tension-type headache
2.8
42.4
245
983
M13.9
ICD-10 Finland
Arthritis, unspecified
3.5
42.3
155
476
L04AA13
ATC
[U] leflunomide
6.0
41.5
75
131
A10AC01
ATC
insulin (human); parenteral
3.3
41.0
175
591
L04AC07
ATC
tocilizumab; parenteral
91.0
40.0
44
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
39.7
255
1078
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
398.7
39.3
39
*
M05BA07
ATC
risedronic acid; oral
4.1
39.3
115
302
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.7
36.6
70
129
M31.3
ICD-10 Finland
Wegener granulomatosis
366.8
36.1
36
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.2
35.8
100
253
P01BA02
ATC
hydroxychloroquine; oral
3.2
35.8
156
532
H57.1
ICD-10 Finland
Ocular pain
4.7
35.7
84
186
AA1AD
NOMESCO Finland
CT of head and brain
2.1
35.4
521
3123
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
34.9
210
855
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
34.6
517
3110
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
9.5
32.8
39
42
A01
ICPC
Pain general/multiple sites
2.7
32.1
194
791
ZX120
NOMESCO Finland
Intravenous
2.7
30.9
188
768
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
30.9
588
3816
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
309.1
29.9
30
*
L01BA01
ATC
methotrexate; systemic
4.1
29.4
84
216
M35.5
ICD-10 Finland
Multifocal fibrosclerosis
+∞
29.3
28
*
J01DB01
ATC
cefalexin; oral
2.3
28.8
1127
9278
M25.5
ICD-10 Finland
Pain in joint
2.0
28.7
449
2709
M05BX04
ATC
denosumab; parenteral
2.8
28.2
159
624
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
27.2
445
2717
R51
ICD-10 Finland
Headache
3.5
26.2
93
278
H34.1
ICD-10 Finland
Central retinal artery occlusion
9.3
25.7
31
34
M79.6
ICD-10 Finland
Pain in limb
1.8
25.5
622
4293
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.1
24.0
103
347
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
23.9
303
1682
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
23.7
198
933
N02BE01
ATC
paracetamol; systemic, rectal
2.8
23.1
1246
10982
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
23.1
698
5086
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.7
22.9
127
493
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
22.8
356
2120
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
22.6
188
883
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
22.6
301
1697
UJF32
NOMESCO Finland
Coloscopy
1.8
22.0
432
2762
N02AX02
ATC
tramadol; systemic, rectal
1.7
21.8
641
4605
H15.1
ICD-10 Finland
Episcleritis
7.5
21.7
31
42
R51.81
ICD-10 Finland
Facial pain NOS
4.4
21.5
54
126
R52.9
ICD-10 Finland
Pain, unspecified
2.4
21.2
164
745
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
21.1
176
827
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
21.0
144
619
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.5
20.9
74
221
R06.0
ICD-10 Finland
Dyspnoea
1.8
20.7
442
2886
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
20.7
572
4023
L95
ICPC
Osteoporosis
2.9
20.3
97
347
A02BC05
ATC
esomeprazole; systemic
1.7
20.3
594
4237
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.6
20.2
69
201
TAB00
NOMESCO Finland
Lumbar puncture
3.3
19.8
77
244
N03AX16
ATC
[U] pregabalin
1.8
19.7
363
2262
S18
ICPC
Laceration/cut
1.7
19.7
677
5030
M79.1
ICD-10 Finland
Myalgia
2.1
19.5
212
1106
XCK00
NOMESCO Finland
Perimetry
2.5
19.4
130
553
N03AX12
ATC
[U] gabapentin; oral
2.0
19.4
265
1500
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
19.1
498
3427
R53
ICD-10 Finland
Malaise and fatigue
1.8
18.5
364
2307
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
18.3
653
4865
L04AA06
ATC
mycophenolic acid; systemic
5.9
18.0
32
55
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
18.0
110
448
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
17.7
276
1628
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
17.4
143
666
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
17.3
447
3050
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
17.3
198
1050
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.8
17.3
293
1772
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
5.0
17.2
37
76
R02
ICPC
Shortness of breath/dyspnoea
2.0
17.0
217
1195
H53.2
ICD-10 Finland
Diplopia
3.2
16.9
69
225
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
16.8
325
2044
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
16.7
16
*
R03AC02
ATC
salbutamol; inhalant
1.6
16.5
710
5492
A10AB05
ATC
insulin aspart; parenteral
2.3
16.5
127
575
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
16.4
135
628
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.2
16.3
65
209
A02BC01
ATC
omeprazole; systemic
1.7
16.1
415
2818
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.3
16.1
130
601
A03
ICPC
Fever
2.0
16.0
185
982
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
16.0
164
833
M03BX02
ATC
tizanidine; oral
1.6
16.0
752
5923
J01AA02
ATC
doxycycline; systemic
1.7
15.9
1047
8970
M79.7
ICD-10 Finland
Fibromyalgia
3.5
15.9
54
157
J01MA14
ATC
moxifloxacin; systemic
2.2
15.9
145
704
C07AB07
ATC
bisoprolol; oral
1.6
15.8
784
6248
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
15.8
136
645
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
15.8
617
4645
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.5
15.8
105
445
J01MA02
ATC
ciprofloxacin; systemic
1.6
15.5
562
4148
L28
ICPC
Limited function/disability (L)
1.7
15.5
317
2020
J01FA10
ATC
azithromycin; systemic
1.6
15.4
668
5142
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
15.3
534
3903
J01FF01
ATC
clindamycin; systemic
1.7
15.0
371
2486
J01CA04
ATC
amoxicillin; systemic
1.7
14.9
1033
8872
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
14.9
200
1118
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
14.9
126
593
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
6.9
14.9
23
34
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
14.7
227
1328
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
14.5
198
1112
H53.4
ICD-10 Finland
Visual field defects
3.8
14.5
45
123
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.4
14.5
98
418
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
14.3
462
3303
L17
ICPC
Foot/toe symptom/complaint
1.6
14.3
409
2839
L01
ICPC
Neck symptom/complaint
1.9
14.2
209
1203
R42
ICD-10 Finland
Dizziness and giddiness
1.7
14.2
361
2431
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
14.2
194
1091
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
14.1
234
1397
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
14.1
870
7204
A02BC03
ATC
lansoprazole; oral
1.6
14.0
426
2997
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.0
14.0
63
218
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
53.9
13.8
16
*
R20.2
ICD-10 Finland
Paraesthesia of skin
2.4
13.8
96
415
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
13.7
138
696
C03CA01
ATC
furosemide; systemic
1.6
13.7
545
4081
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
13.4
263
1649
E0000UV, ,
ATC
1.6
13.3
539
4042
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.8
13.3
68
253
J01FA06
ATC
roxithromycin; oral
1.6
13.2
541
4067
N05CF01
ATC
zopiclone; oral
1.6
13.2
478
3495
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.9
13.1
38
99
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
13.0
266
1685
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
12.9
120
586
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
12.8
137
707
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
12.7
210
1251
M05BA06
ATC
ibandronic acid; systemic
3.0
12.7
56
192
M31.4
ICD-10 Finland
Aortic arch syndrome [Takayasu]
+∞
12.5
12
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.3
12.5
25
48
SPAT1153
SPAT
Removal of sutures
1.6
12.5
472
3475
CS494
NOMESCO Finland
Other visual field testing
3.0
12.5
54
183
M30.0
ICD-10 Finland
Polyarteritis nodosa
131.2
12.5
13
*
R05
ICD-10 Finland
Cough
1.7
12.4
288
1886
A04
ICPC
Weakness/tiredness general
1.8
12.4
227
1393
SPAT1263
SPAT
Sampling
1.5
12.4
563
4314
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
12.3
344
2359
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
12.3
366
2550
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
12.2
425
3068
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.4
12.2
86
374
JN4AD
NOMESCO Finland
Body CT examination
1.9
12.1
161
895
M54.5
ICD-10 Finland
Low back pain
1.5
12.0
450
3299
H02AB09
ATC
hydrocortisone; systemic
3.4
12.0
42
125
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
12.0
316
2136
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
11.9
159
884
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.0
11.9
126
646
L99
ICPC
Musculoskeletal disease other
3.7
11.9
38
106
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
11.9
577
4470
A46
ICD-10 Finland
Erysipelas
1.7
11.9
223
1378
H02AB04
ATC
methylprednisolone; systemic
1.8
11.8
209
1268
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.1
11.8
117
586
R03BB04
ATC
tiotropium bromide; inhalant
1.9
11.8
167
947
A07EC01
ATC
sulfasalazine; oral, rectal
2.1
11.8
112
552
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
11.7
178
1033
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.5
11.7
75
313
R01AD09
ATC
mometasone; nasal
1.5
11.6
519
3950
H47.1
ICD-10 Finland
Papilloedema, unspecified
10.1
11.5
22
22
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.1
11.5
114
571
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.5
368
2601
M31.1
ICD-10 Finland
Thrombotic microangiopathy
121.0
11.4
12
*
B01AC04
ATC
clopidogrel; oral
1.6
11.3
280
1861
L18
ICPC
Muscle pain
2.6
11.2
63
246
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
11.2
169
977
PA6AD
NOMESCO Finland
CT of neck arteries
2.9
11.2
52
184
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
11.2
140
763
Z3231
NOMESCO Finland
Registered nurse
1.6
11.1
374
2669
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
11.1
353
2489
5BA08, ,
NOMESCO Finland
8.6
11.0
23
27
G50.1
ICD-10 Finland
Atypical facial pain
3.5
11.0
37
107
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.5
11.0
38
112
J02AC01
ATC
fluconazole; systemic
1.5
11.0
460
3440
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.1
11.0
46
153
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
11.0
824
6926
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
11.0
248
1608
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.8
11.0
54
197
R01AD12
ATC
fluticasone furoate; nasal
1.6
10.9
321
2221
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
10.9
267
1767
L03
ICPC
Low back symptom/complaint
1.6
10.9
353
2497
R60.0
ICD-10 Finland
Localized oedema
1.8
10.9
195
1187
R52.2
ICD-10 Finland
Other chronic pain
2.6
10.9
63
250
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.4
10.9
38
113
R01AD08
ATC
fluticasone; nasal
1.6
10.9
322
2232
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.7
10.8
34
94
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
10.8
244
1581
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
8.9
10.8
22
25
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
8.9
10.8
22
25
UJF92
NOMESCO Finland
Capsular endoscopy
3.5
10.8
36
104
WZC30
NOMESCO Finland
Teaching
1.7
10.7
219
1382
J05AB01
ATC
aciclovir; systemic
1.6
10.7
288
1952
R03DC03
ATC
montelukast; oral
1.7
10.6
199
1227
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
10.6
138
762
H26.3
ICD-10 Finland
Drug-induced cataract
9.3
10.5
21
23
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.3
10.4
38
116
4AC07, ,
NOMESCO Finland
110.9
10.4
11
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
10.4
10
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
10.4
10
*
TNG10
NOMESCO Finland
Puncture of knee
4.3
10.3
26
61
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.7
10.3
54
204
R74
ICPC
Upper respiratory infection acute
1.6
10.2
292
2005
J01MA12
ATC
levofloxacin; systemic
1.6
10.2
270
1820
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
10.1
168
999
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.8
10.1
150
863
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.3
10.0
78
355
R05
ICPC
Cough
1.6
10.0
307
2140
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.7
10.0
54
207
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
10.0
236
1545
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
10.0
734
6096
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
3.5
9.9
34
100
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
9.8
74
332
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
9.8
535
4197
R06AE07
ATC
cetirizine; oral
1.5
9.8
513
3993
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
9.8
129
715
F29
ICPC
Eye symptom/complaint other
1.9
9.7
130
723
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.6
9.7
57
228
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.4
9.7
66
283
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
13.5
9.7
16
12
SPAT1301
SPAT
No procedures
1.5
9.6
443
3359
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
9.6
104
538
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
9.6
505
3930
G45.3
ICD-10 Finland
Amaurosis fugax
3.0
9.6
42
144
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4.6
9.5
22
48
XF402
NOMESCO Finland
ECG with work load test
1.7
9.5
167
1011
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
9.4
276
1900
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.8
9.4
135
768
C08CA01
ATC
amlodipine; oral
1.4
9.4
600
4833
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.9
9.4
119
650
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
9.4
167
1013
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
9.4
9
*
4AC0X, ,
NOMESCO Finland
+∞
9.4
9
*
H92.0
ICD-10 Finland
Otalgia
2.3
9.4
72
326
L08
ICPC
Shoulder symptom/complaint
1.5
9.3
290
2027
B01AF02
ATC
apixaban; oral
1.6
9.3
220
1441
G47.3
ICD-10 Finland
Sleep apnoea
1.6
9.2
259
1765
N06AX21
ATC
duloxetine; oral
1.8
9.2
147
865
M10.9
ICD-10 Finland
Gout, unspecified
2.0
9.2
106
562
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.5
9.1
31
91
R63.4
ICD-10 Finland
Abnormal weight loss
2.3
9.0
65
286
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
9.0
110
594
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
9.0
317
2272
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
8.9
201
1298
R03BA05
ATC
fluticasone; inhalant
1.6
8.9
224
1486
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.8
8.9
27
73
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.5
8.9
53
214
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.0
8.8
95
491
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
8.8
95
492
S97
ICPC
Chronic ulcer skin
1.9
8.8
104
556
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.7
522
4143
B02.9
ICD-10 Finland
Zoster without complication
1.9
8.7
107
580
J31.0
ICD-10 Finland
Chronic rhinitis
2.0
8.6
98
516
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
8.6
72
338
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.0
8.6
38
131
L01AA01
ATC
cyclophosphamide; systemic
8.3
8.6
18
22
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
8.6
235
1592
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
4.1
8.5
23
57
N02BF01
ATC
gabapentin; oral
1.9
8.5
114
635
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
8.4
102
549
R03BA02
ATC
budesonide; inhalant
1.6
8.3
227
1534
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
8.3
8
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.1
8.3
34
112
SPAT1310
SPAT
Counselling related to known health issue
1.4
8.3
411
3144
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
8.3
86
439
JN4BD
NOMESCO Finland
Extensive body CT
1.7
8.3
162
1009
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
8.2
349
2590
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
8.2
204
1348
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.4
8.2
55
235
R55
ICD-10 Finland
Syncope and collapse
1.7
8.2
174
1107
L20
ICPC
Joint symptom/complaint NOS
2.5
8.1
52
217
J01FA09
ATC
clarithromycin; systemic
1.5
8.1
353
2634
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
8.1
617
5085
NXL00
NOMESCO Finland
Biopsy of muscle
11.8
8.1
14
12
R01AD01
ATC
beclometasone; nasal
1.6
8.0
182
1176
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.9
8.0
108
603
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.5
8.0
50
207
R11
ICD-10 Finland
Nausea and vomiting
1.8
8.0
121
701
SPAT1260
SPAT
Consultation of another employee
1.5
7.9
237
1636
XG410
NOMESCO Finland
Flow-volume spirometry
2.3
7.9
59
265
K04.1
ICD-10 Finland
Necrosis of pulp
1.8
7.8
113
644
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.5
7.8
26
75
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.8
484
3847
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.0
7.7
33
112
R04.2
ICD-10 Finland
Haemoptysis
2.3
7.7
54
236
D01
ICPC
Abdominal pain/cramps general
1.7
7.7
137
832
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
7.6
85
445
Z00.0
ICD-10 Finland
General medical examination
1.5
7.6
252
1776
H29
ICPC
Ear symptom/complaint other
1.7
7.6
157
991
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
7.6
353
2661
H05AA02
ATC
teriparatide; parenteral
6.7
7.6
18
27
H26.4
ICD-10 Finland
After-cataract
1.6
7.6
185
1217
N06AA09
ATC
amitriptyline; systemic
1.7
7.6
143
881
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
7.6
91
489
C08CA05
ATC
nifedipine; systemic
1.9
7.6
94
511
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.8
7.5
111
637
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.5
233
1619
SFA20
NOMESCO Finland
Two-surface restoration
1.4
7.5
623
5184
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.5
225
1553
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
2.6
7.5
43
171
G50.0
ICD-10 Finland
Trigeminal neuralgia
2.9
7.5
33
114
K07.60
ICD-10 Finland
Snapping jaw
2.4
7.4
50
214
Z01.2
ICD-10 Finland
Dental examination
1.4
7.4
487
3898
A07AA02
ATC
nystatin; oral
1.9
7.4
96
529
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
7.4
170
1102
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
7.4
289
2107
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
7.4
106
604
PD5AD
NOMESCO Finland
CT of aorta
2.7
7.4
38
143
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
4.0
7.4
20
50
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
7.3
78
402
M01AE02
ATC
naproxen; oral, rectal
1.4
7.3
658
5537
G43.9
ICD-10 Finland
Migraine, unspecified
2.4
7.3
47
197
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
8.4
7.3
15
18
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
7.3
120
711
A11
ICPC
Chest pain NOS
1.7
7.3
125
750
4AC0L, ,
NOMESCO Finland
+∞
7.3
7
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
7.3
7
*
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
7.3
7
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
7.3
167
1082
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
7.2
77
397
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
7.2
129
783
A02BA02
ATC
ranitidine; systemic
1.5
7.2
280
2037
M01AH03
ATC
valdecoxib; oral
1.9
7.2
84
447
UDM02
NOMESCO Finland
Sinoscopy
2.9
7.2
32
111
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
7.2
363
2775
Z2221
NOMESCO Finland
Medical doctor
1.4
7.2
338
2552
M05.2
ICD-10 Finland
Rheumatoid vasculitis
30.2
7.2
9
*
ZXA00
NOMESCO Finland
Right side
1.4
7.1
381
2940
R10.0
ICD-10 Finland
Acute abdomen
2.6
7.1
41
163
318
Kela drug reimbursment
Teriparatide
6.1
7.1
18
30
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.6
7.1
39
152
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.1
7.1
29
96
207
Kela drug reimbursment
Chronic arrhythmias
1.5
7.0
264
1908
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
3.2
7.0
27
86
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.5
7.0
23
66
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
7.0
149
948
R21
ICPC
Throat symptom/complaint
1.6
7.0
179
1191
M48.0
ICD-10 Finland
Spinal stenosis
1.6
7.0
196
1332
D07AD01
ATC
clobetasol; topical
1.5
7.0
208
1433
C08CA13
ATC
lercanidipine; oral
1.5
7.0
226
1585
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.0
7.0
79
417
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.0
100
570
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.0
249
1782
SFA10
NOMESCO Finland
One-surface restoration
1.4
6.9
602
5025
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
6.9
181
1210
B01AA03
ATC
warfarin; systemic
1.4
6.9
303
2255
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
4.0
6.9
19
48
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.5
6.9
43
178
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
6.9
82
440
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
3.6
6.9
22
62
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
6.9
151
968
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.7
6.9
35
131
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
6.9
46
197
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.1
6.9
59
281
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.8
366
2823
F01
ICPC
Eye pain
2.6
6.8
37
143
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
4.1
6.8
18
44
M01AH02
ATC
rofecoxib; oral
1.5
6.8
192
1306
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
6.8
83
449
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.8
6.8
104
604
XKD00
NOMESCO Finland
Uroflowmetry
1.5
6.8
208
1441
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
6.8
229
1619
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
6.8
79
421
SFA30
NOMESCO Finland
Three-surface restoration
1.4
6.8
467
3756
J05AB11
ATC
valaciclovir; oral
1.6
6.7
181
1217
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
2.8
6.7
33
121
L19
ICPC
Muscle symptom/complaint NOS
2.5
6.7
39
156
TGC00
NOMESCO Finland
Bronchial lavation
2.5
6.7
40
162
K30
ICD-10 Finland
Functional dyspepsia
1.7
6.7
136
854
PAA99
NOMESCO Finland
Exploration of other arterial branch originating from aortic arch arteries
22.6
6.7
9
*
R03BA01
ATC
beclometasone; inhalant
1.6
6.7
175
1171
J01DA01
ATC
[U] cefalexin
1.3
6.6
763
6628
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.6
413
3264
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
6.6
425
3376
H34.2
ICD-10 Finland
Other retinal artery occlusions
5.5
6.6
18
33
H46
ICD-10 Finland
Optic neuritis
5.9
6.6
17
29
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.6
6.6
21
59
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.6
272
2000
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.2
6.6
25
79
R96
ICPC
Asthma
1.7
6.5
128
797
PG1AE
NOMESCO Finland
Ultrasound examination of artery not elsewher classified
6.9
6.5
15
22
C10AA05
ATC
atorvastatin; oral
1.3
6.5
601
5049
E000006, ,
ATC
1.8
6.5
91
515
J01CF05
ATC
flucloxacillin; systemic
1.9
6.5
76
406
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
6.5
276
2041
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.0
6.5
65
329
D07AC01
ATC
betamethasone; topical
1.4
6.5
439
3517
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
6.4
143
919
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
4.0
6.4
18
46
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.4
220
1559
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
6.4
445
3576
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.4
615
5193
J20
ICD-10 Finland
Acute bronchitis
1.7
6.4
128
802
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.8
6.4
19
51
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
6.3
238
1718
SPAT1285
SPAT
Provision of consultation response
2.0
6.3
70
367
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
6.3
81
446
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.3
545
4526
SPAT1211
SPAT
Application of soft bandage
1.7
6.3
118
726
L04AA01
ATC
[U] ciclosporin
3.5
6.3
21
61
J37.0
ICD-10 Finland
Chronic laryngitis
2.3
6.3
46
205
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.1
6.3
60
298
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
6.3
6
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
6.3
6
*
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
6.3
67
347
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
6.2
81
448
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.7
6.2
123
769
L29
ICPC
Musculoskeletal sympt/complt other
1.7
6.2
112
683
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
2.4
6.2
41
175
1222
FHL
Arthroscopy and synovial surgery
4.0
6.2
17
43
N06AX11
ATC
mirtazapine; oral
1.4
6.2
417
3333
L04AK01
ATC
leflunomide; oral
6.3
6.2
15
24
H53.8
ICD-10 Finland
Other visual disturbances
3.2
6.2
23
72
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
5.4
6.2
17
32
R13
ICD-10 Finland
Dysphagia
1.8
6.2
99
584
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
3.4
6.2
21
62
R07.3
ICD-10 Finland
Other chest pain
1.6
6.1
137
882
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.1
304
2308
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.1
133
851
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
6.1
44
195
H25.0
ICD-10 Finland
Senile incipient cataract
1.7
6.1
103
617
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.9
6.1
68
358
R81
ICPC
Pneumonia
2.2
6.0
49
229

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
516
1151
6.64
236.85
1.6
1.2
541.57
392.64
titre
0.99
115
250
273
326
10.25
218.93
2.1
1.4
256.84
178.18
titre
0.23
19
11
1009
5066
4.94
154.03
12.3
5.8
—
—
—
0
0
1035
5410
4.93
146.62
11.9
5.1
0.65
0.61
e9/l
4.55
948
4595
1036
5421
4.94
146.50
11.9
5.2
0.04
0.04
e9/l
0.44
948
4613
1051
5611
4.96
143.24
12.0
5.4
0.16
0.19
e9/l
12.16
966
4835
1041
5531
4.87
142.45
12.0
5.3
1.83
1.92
e9/l
0.76
968
4809
942
4955
3.99
123.06
12.4
5.4
0.58
0.66
%
4.33
911
4565
956
5117
3.99
120.72
12.8
5.7
8.36
8.87
%
5.49
926
4721
171
238
8.08
118.89
1.7
1.1
0.25
0.24
g/l
0.21
159
220
949
5097
3.91
118.20
12.4
5.4
2.04
2.83
%
29.55
919
4700
172
249
7.77
115.47
1.8
1.2
1.28
1.19
g/l
2.36
162
232
333
895
4.61
115.26
1.6
2.8
—
—
—
0
0
956
5210
3.87
115.25
12.6
5.6
24.07
26.57
%
10.55
926
4824
465
1597
3.92
115.06
1.4
1.2
31.77
41.98
iu/ml
0.91
143
494
942
5125
3.78
112.91
12.2
5.4
62.19
58.12
%
19.67
910
4739
449
1534
3.89
111.50
1.4
1.2
7.32
14.44
u/ml
1.59
149
535
1073
6443
4.26
108.85
14.4
8.7
5.05
4.18
e9/l
26.41
987
5582
136
164
9.11
106.15
1.8
1.1
—
—
—
0
0
181
304
6.72
105.65
1.4
1.1
0.16
1.23
u/ml
0.79
14
25
1042
6297
3.88
100.75
7.9
6.4
1.22
1.21
mmol/l
1.51
933
5330
881
4837
3.37
98.72
3.0
2.2
82.12
79.84
nmol/l
1.46
820
4191
347
1086
3.96
96.32
1.7
3.0
65.19
66.16
g/l
1.41
316
973
736
3739
3.13
92.26
2.7
2.1
111.77
232.88
u/l
5.59
699
3475
950
5754
3.20
84.11
6.6
5.7
1.22
1.21
mmol/l
0.57
916
5190
307
988
3.73
80.60
2.2
2.1
339.88
383.18
nmol/l
3.31
277
886
1189
8396
4.53
79.35
15.4
3.9
17.33
14.40
mm/h
6.86
1150
7613
286
955
3.53
70.25
1.4
1.5
—
—
—
0
0
260
826
3.66
68.82
1.3
1.5
—
—
—
0
0
265
868
3.56
66.83
1.4
1.5
—
—
—
0
0
264
864
3.56
66.65
7.1
3.4
0.47
0.65
%
1.14
127
294
278
964
3.37
63.88
7.7
3.6
0.93
0.90
%
0.11
135
353
187
501
4.17
62.86
1.5
2.8
3.87
3.58
g/l
2.28
167
444
187
502
4.16
62.68
1.5
2.8
8.79
7.45
g/l
12.90
167
444
265
903
3.41
62.53
7.9
3.6
0.03
0.11
%
2.41
121
293
178
465
4.26
61.86
1.5
2.8
3.78
2.97
g/l
11.04
157
408
1110
7992
3.20
60.78
8.5
4.6
—
—
—
0
0
237
766
3.54
60.65
2.4
2.8
10.18
10.91
g/l
1.06
216
685
249
839
3.41
59.63
8.2
3.6
0.02
0.41
%
0.54
107
237
188
529
3.97
58.93
1.1
1.4
—
—
—
0
0
175
469
4.14
58.66
1.5
2.8
9.52
10.41
g/l
1.59
152
410
636
3566
2.48
57.38
5.1
4.2
—
—
—
0
0
659
3776
2.46
56.40
4.5
3.9
7.40
7.40
ph
0.10
138
719
200
611
3.67
55.51
1.5
1.8
1.19
1.47
g/l
0.78
182
544
199
620
3.59
53.54
2.7
2.6
33.62
29.13
au/ml
—
5
29
1174
8999
3.36
52.16
12.9
7.4
72.27
80.01
u/l
9.39
1148
8373
150
395
4.15
51.29
1.5
2.6
33.00
37.59
g/l
12.02
127
338
183
555
3.66
51.18
1.4
1.4
28.17
57.47
au/ml
—
6
34
838
5623
2.30
46.35
6.2
4.2
0.00
0.00
estimate
0.50
200
996
99
203
5.18
46.08
1.5
1.1
8.24
3.31
u/ml
0.90
17
14
100
209
5.09
45.54
1.5
1.1
15.72
3.70
u/ml
1.01
18
25
751
4854
2.24
45.01
17.7
10.0
0.00
0.00
e9/l
0.39
644
3951
827
5560
2.26
44.94
6.2
4.2
0.00
0.00
estimate
0.75
216
1105
821
5560
2.22
43.02
7.9
5.6
0.00
0.00
estimate
-0.00
204
1006
969
7064
2.32
41.74
5.7
4.6
6.71
6.83
mmol/l
1.01
932
6646
117
304
4.12
40.54
1.3
1.7
—
—
—
0
0
144
437
3.57
39.93
1.6
3.7
1.87
1.65
ratio
0.12
14
34
109
272
4.27
39.84
1.6
2.0
10.47
12.23
mg/l
1.63
100
245
55
73
7.81
39.27
1.4
1.1
185.00
67.50
titre
0.56
12
12
145
450
3.49
38.82
1.7
3.7
39.91
64.40
mg/l
1.04
114
372
145
450
3.49
38.82
1.7
3.8
31.05
86.11
mg/l
1.18
115
374
546
3245
2.15
38.79
2.7
2.2
3.13
3.16
mg/l
0.11
472
2709
44
47
9.64
37.26
1.2
1.1
5.32
5.28
u/l
0.02
30
39
155
530
3.17
35.41
1.7
1.9
1.45
1.89
ug/l
0.24
130
455
1026
7909
2.24
34.84
6.8
5.1
188.00
2141.23
e6/l
—
6
136
69
137
5.25
33.23
1.4
1.7
0.78
0.82
g/l
0.09
51
103
112
327
3.64
32.79
1.6
4.0
—
—
—
0
0
664
4439
1.98
32.45
5.1
3.8
5.70
5.83
ph
0.28
15
198
645
4275
1.98
32.27
5.2
3.8
85.49
107.78
e6/l
0.36
499
3103
60
108
5.77
32.12
1.4
1.1
—
—
—
0
0
672
4523
1.97
32.08
3.5
2.7
175.28
139.42
ug/l
1.72
611
4060
359
1946
2.15
31.12
2.7
2.4
11.17
12.16
umol/l
1.81
331
1800
853
6298
1.97
30.24
5.6
6.1
10.39
11.69
umol/l
2.42
820
5954
542
3445
1.96
30.06
3.9
3.2
0.30
0.55
e6/l
3.30
447
2647
344
1858
2.14
29.95
1.5
1.5
2.42
2.58
g/l
0.66
235
1048
567
3683
1.93
29.28
2.7
2.4
57.58
60.40
u/l
0.37
527
3351
333
1796
2.13
28.98
2.7
2.4
2.25
2.30
g/l
0.76
305
1653
521
3304
1.94
28.79
3.9
3.2
—
—
—
0
0
571
3735
1.92
28.72
4.0
3.3
31.90
77.25
e6/l
1.66
477
2897
316
1694
2.13
27.80
2.8
2.4
19.94
21.56
%
1.11
270
1433
663
4603
1.87
27.27
2.3
2.2
—
—
—
0
0
461
2855
1.93
26.96
9.5
6.5
—
—
—
0
0
473
2963
1.92
26.66
2.8
2.8
3769.91
8065.27
umol/l
1.45
411
2521
755
5492
1.85
26.44
5.1
4.5
33.52
34.83
g/l
8.37
705
5078
63
141
4.64
26.37
1.6
1.5
52.18
67.84
%
1.85
39
92
816
6085
1.86
26.34
21.5
17.8
1.30
1.32
inr
0.24
225
1667
84
237
3.71
25.81
1.2
1.2
3.76
3.90
mmol/l
0.76
76
226
76
201
3.95
25.60
1.2
1.2
—
—
—
0
0
80
220
3.80
25.51
1.6
1.6
—
—
—
0
0
44
74
6.11
25.23
1.2
1.5
0.32
0.40
g/l
0.63
35
51
44
74
6.11
25.23
1.2
1.5
5.97
7.23
g/l
0.91
34
51
44
74
6.11
25.23
1.2
1.5
2.72
2.67
g/l
0.05
35
52
89
267
3.50
24.95
1.2
1.3
466.93
518.23
mg/l
0.60
83
253
64
152
4.37
24.87
1.5
1.1
64.83
13.92
u/ml
—
6
13
427
2635
1.91
24.85
3.2
2.6
4.81
5.47
e6/l
0.56
388
2376
28
28
10.19
24.77
1.1
1.0
—
—
—
0
0
36
50
7.37
24.67
1.1
1.1
—
—
—
0
0
76
207
3.83
24.57
1.0
1.0
—
—
—
0
0
288
1555
2.08
24.54
2.3
2.5
1.91
1.83
%
0.50
261
1358
100
331
3.18
23.96
1.5
1.4
—
—
—
0
0
410
2541
1.88
23.28
3.6
3.0
506.23
532.52
mosm/kgh2o
1.94
348
2171
676
4872
1.78
23.27
5.6
4.0
29.19
50.95
ng/l
2.29
538
3719
1243
10934
2.76
23.27
35.3
16.1
23.68
26.11
mg/l
2.11
1174
8837
43
77
5.74
23.14
1.2
1.5
—
—
—
0
0
230
1167
2.17
22.92
2.3
2.5
71.56
69.28
e9/l
0.36
175
905
469
3054
1.82
22.59
7.0
4.4
0.00
0.00
estimate
0.50
199
969
600
4207
1.77
22.46
3.3
3.0
1526.30
1616.10
ng/l
0.19
534
3628
113
428
2.79
21.30
1.9
2.3
270.42
550.17
ug/l
1.11
101
405
211
1083
2.12
20.26
2.2
2.0
249.35
144.49
ug/g
1.37
171
842
64
177
3.75
20.25
1.5
1.5
—
—
—
0
0
421
2728
1.79
20.16
5.8
4.0
—
—
—
0
0
143
625
2.44
20.13
1.5
1.7
2.10
1.57
g/l
5.40
122
538
717
5404
1.70
19.80
2.3
2.1
91.62
93.72
pmol/l
0.59
391
2670
283
1633
1.93
19.55
1.3
1.2
—
—
—
0
0
44
94
4.81
19.48
1.2
1.1
—
—
—
0
0
44
94
4.81
19.48
1.1
1.1
—
—
—
0
0
122
510
2.53
18.87
2.2
2.0
—
—
—
0
0
376
2405
1.78
18.56
1.9
1.6
1.38
1.41
mg/l
0.06
296
1885
53
137
3.99
18.44
1.1
1.1
—
—
—
0
0
592
4307
1.67
18.16
3.8
3.5
—
—
—
0
0
66
201
3.40
18.08
4.2
3.0
63.59
59.95
%
1.31
66
201
309
1881
1.83
17.90
2.0
1.9
29.28
29.69
s
0.44
301
1812
597
4375
1.65
17.65
3.1
3.5
2.34
2.36
mmol/l
2.14
505
3763
233
1309
1.94
17.25
5.6
4.4
—
—
—
0
0
408
2720
1.72
17.18
2.0
1.8
1141.25
1187.22
nmol/l
0.45
303
1988
38
80
4.86
17.13
1.4
1.9
—
—
—
0
0
62
191
3.35
16.69
4.0
2.8
5.19
4.53
e9/l
1.20
62
191
81
294
2.87
16.51
1.7
1.7
10551.41
17357.94
e6/l
1.14
64
218
230
1307
1.92
16.40
2.1
1.8
—
—
—
0
0
70
237
3.06
16.14
1.3
1.1
82.86
83.75
titre
—
7
16
335
2148
1.74
16.06
3.3
2.8
1.90
1.27
e6/l
0.29
218
1239
61
194
3.25
15.62
1.2
1.2
—
—
—
0
0
999
8483
1.69
15.33
4.6
4.1
15.37
15.10
pmol/l
2.60
906
7522
43
110
4.00
15.20
1.0
1.2
—
—
—
0
0
46
124
3.81
15.13
2.7
3.4
56.49
56.07
%
0.04
41
105
211
1217
1.87
14.25
3.2
2.5
5.04
6.43
ug/l
1.07
175
1054
81
321
2.62
13.97
1.1
1.4
—
—
—
0
0
23
17
13.74
13.74
1.1
1.1
—
—
—
0
0
23
17
13.74
13.74
1.1
1.1
—
—
—
0
0
23
17
13.74
13.74
1.1
1.1
—
—
—
0
0
49
148
3.40
13.64
2.9
4.3
—
—
—
0
0
189
1076
1.88
13.25
4.7
3.7
1.22
1.23
mmol/l
1.61
177
925
65
237
2.83
13.17
1.2
1.3
2058.73
725.67
e6/l
0.32
52
196
65
237
2.83
13.17
1.2
1.2
24.31
42.47
e6/l
0.27
48
189
217
1294
1.81
13.10
1.6
1.4
—
—
—
0
0
23
39
5.98
13.08
1.1
1.2
54.00
45.13
ng/l
—
5
8
184
1055
1.86
12.59
3.4
3.4
90.15
90.68
ng/l
0.02
165
885
183
1060
1.84
12.11
5.3
3.6
—
—
—
0
0
300
1997
1.65
12.09
2.6
3.0
0.81
0.81
mmol/l
0.08
273
1849
301
2006
1.64
12.07
3.6
3.0
4.48
2.62
e6/l
1.30
183
1103
413
2973
1.56
11.98
4.3
3.9
89.73
86.70
%
1.60
405
2900
372
2615
1.58
11.96
2.8
3.1
2.47
2.47
mmol/l
0.44
319
2299
28
62
4.59
11.92
1.1
1.1
—
—
—
0
0
358
2496
1.59
11.92
5.8
3.9
102.50
315.65
ng/l
4.11
306
2127
46
149
3.16
11.48
1.1
1.1
—
—
—
0
0
1157
10464
1.75
11.41
7.4
6.5
41.15
40.75
mmol/mol
0.82
1076
9471
256
1661
1.67
11.33
6.1
4.8
1.06
1.03
mmol/l
0.85
237
1510
1218
11196
1.91
11.23
26.6
15.8
—
—
—
0
0
396
2860
1.54
11.18
5.9
3.9
—
—
—
0
0
184
1094
1.79
11.14
6.2
6.1
1.39
1.39
mmol/l
0.01
175
1073
44
142
3.17
11.06
1.2
1.2
296.09
303.51
u/ml
0.05
23
75
24
51
4.77
10.73
1.2
1.3
7.67
2.11
%
—
6
9
434
3233
1.50
10.47
1.7
1.6
19.36
20.56
nmol/l
1.03
377
2673
262
1742
1.63
10.47
2.1
2.0
—
—
—
0
0
36
106
3.46
10.46
1.4
1.4
34.10
29.31
%
0.27
20
67
1131
10225
1.66
10.44
5.9
5.0
1.85
2.15
mu/l
1.81
1036
9126
129
701
1.93
10.36
2.6
2.5
—
—
—
0
0
35
102
3.50
10.33
1.5
1.2
—
—
—
0
0
20
39
5.19
9.85
1.1
1.0
—
—
—
0
0
104
536
2.02
9.72
1.3
1.2
199.39
222.08
u/ml
0.12
96
484
45
159
2.89
9.71
1.1
1.3
—
—
—
0
0
1245
11616
1.94
9.65
29.9
19.5
139.34
139.59
mmol/l
2.40
1227
11293
127
705
1.88
9.56
3.7
3.1
4.99
5.69
e9/l
0.30
85
535
21
44
4.83
9.55
1.1
1.1
—
73.43
%
—
0
7
177
1087
1.72
9.53
2.4
2.3
29.49
36.34
u/l
1.80
146
911
769
6477
1.44
9.45
3.7
3.1
51.86
52.74
u/l
0.12
716
5853
19
37
5.19
9.37
1.1
1.0
—
—
—
0
0
105
551
1.98
9.34
1.3
1.3
—
—
—
0
0
1244
11635
1.90
9.10
30.4
19.7
3.97
3.99
mmol/l
2.59
1221
11297
196
1254
1.66
9.04
1.3
1.3
—
—
—
0
0
299
2128
1.52
8.74
1.4
1.2
1.55
1.33
u/ml
0.17
73
531
175
1103
1.67
8.53
7.4
6.1
10.67
10.72
mmol/l
0.03
168
1047
1237
11587
1.82
8.45
21.0
11.1
23.21
24.24
u/l
1.98
1215
11080
187
1209
1.63
8.25
4.0
3.4
1.87
1.96
mmol/l
0.15
168
996
40
146
2.79
8.17
1.1
1.0
—
—
—
0
0
68
325
2.15
7.80
1.2
1.2
—
—
—
0
0
1023
9224
1.45
7.73
34.1
19.5
15.46
15.46
%
0.00
1006
9042
162
1028
1.65
7.68
7.3
7.3
—
—
—
0
0
432
3380
1.41
7.55
2.9
3.1
30.68
34.08
u/l
1.27
408
3195
185
1219
1.60
7.54
3.9
3.3
5.73
5.80
kpa
0.51
179
1185
37
138
2.73
7.29
1.2
1.1
—
—
—
0
0
124
743
1.74
7.27
1.3
1.2
—
—
—
0
0
37
139
2.71
7.19
1.1
1.4
110.11
106.46
u/ml
—
8
21
1115
10273
1.49
7.08
4.6
4.2
1.28
1.27
mmol/l
0.10
996
9074
30
102
2.99
6.99
1.2
1.2
—
—
—
0
0
479
3853
1.38
6.98
5.3
4.3
—
—
—
0
0
1255
11901
1.79
6.90
44.6
24.3
39.04
39.11
%
0.18
1176
10981
1255
11902
1.79
6.88
44.6
24.2
262.70
245.55
e9/l
14.30
1237
11537
1255
11902
1.79
6.88
44.6
24.2
7.77
6.78
e9/l
42.50
1236
11488
1255
11903
1.79
6.86
44.4
24.2
92.00
91.68
fl
1.64
1240
11675
1255
11904
1.79
6.85
44.6
24.2
4.31
4.38
e12/l
6.09
1235
11489
1255
11904
1.79
6.85
44.4
24.1
30.21
30.39
pg
2.89
1240
11676
1255
11907
1.78
6.80
44.9
24.4
129.08
132.05
g/l
11.91
1241
11680
88
486
1.87
6.77
4.1
3.9
24.84
25.04
mmol/l
0.27
81
447
1166
10876
1.53
6.64
5.9
5.1
5.91
6.06
mmol/l
3.28
1062
9645
1152
10725
1.51
6.55
5.2
4.8
4.54
4.54
mmol/l
0.02
1043
9667
1143
10628
1.50
6.50
5.2
4.7
1.55
1.49
mmol/l
4.37
1027
9502
189
1295
1.53
6.47
2.2
2.6
6.56
8.73
umol/l
0.92
167
1135
72
378
1.96
6.46
4.6
3.2
—
—
—
0
0
35
136
2.62
6.40
1.4
2.2
—
—
—
0
0
211
1487
1.50
6.32
6.8
6.4
4.97
5.09
kpa
1.04
199
1412
211
1487
1.50
6.32
6.7
6.4
12.08
12.03
kpa
0.04
199
1414
98
573
1.77
6.28
4.1
3.7
—
—
—
0
0
68
356
1.96
6.16
1.4
1.4
279.31
280.10
ug/g
0.01
35
213
49
227
2.20
6.12
1.6
1.8
4.69
4.67
mmol/24h
0.01
44
190
92
532
1.78
6.12
2.8
2.7
—
—
—
0
0
31
116
2.71
6.11
1.5
1.2
17748.47
163765.68
e6/l
1.02
19
81
30
111
2.74
6.04
1.3
1.2
4.08
5.92
u/ml
0.38
12
50
14
21
6.72
6.04
1.1
1.0
—
—
—
0
0
78
432
1.86
5.98
2.0
2.9
0.24
0.28
g/l
0.30
34
153
171
1168
1.53
5.93
2.0
2.0
0.22
0.20
g/l
2.12
151
1085
127
814
1.62
5.80
8.2
7.9
0.63
0.66
%
0.44
127
806
641
5498
1.32
5.75
2.9
2.7
—
—
—
0
0
123
785
1.62
5.71
4.1
3.6
5.05
5.18
kpa
0.93
115
748
189
1329
1.49
5.71
7.2
6.7
96.06
95.35
%
1.41
181
1274
175
1212
1.51
5.69
3.3
2.9
209.12
226.68
ng/l
0.22
158
1112
17
46
3.73
5.65
1.6
1.4
—
—
—
0
0
17
46
3.73
5.65
1.7
1.6
—
—
—
0
0
208
1496
1.46
5.61
6.8
6.4
1.09
1.21
mmol/l
0.18
166
1179
67
362
1.90
5.56
1.7
1.6
—
—
—
0
0
34
142
2.43
5.41
1.9
2.3
0.66
1.40
g/24h
1.41
15
64
50
246
2.07
5.40
1.7
1.7
5.41
4.96
iu/l
0.04
11
75
120
775
1.60
5.32
4.1
3.6
7.41
7.40
ph
0.17
15
102
16
34
4.75
5.30
1.1
1.1
1.03
1.09
ratio
—
5
10
9
8
11.31
5.29
2.2
1.4
—
—
—
0
0
1169
11024
1.45
5.14
5.9
5.4
2.56
2.62
mmol/l
1.38
1056
9884
174
1230
1.48
5.12
7.6
7.1
119.36
119.31
g/l
0.01
169
1193
8
6
13.40
5.08
1.1
1.0
—
—
—
0
0
125
825
1.57
5.06
8.4
7.7
1.39
1.33
%
0.28
125
816
97
602
1.66
5.05
2.9
3.1
4.36
4.38
pmol/l
0.05
80
520
149
1024
1.51
5.03
3.3
2.7
4.68
4.43
kpa
0.74
143
993
67
377
1.82
4.93
1.7
1.9
21.73
21.60
s
0.05
60
342
18
56
3.24
4.90
2.3
1.9
0.16
0.22
e9/l
0.80
18
49
87
530
1.69
4.87
1.3
1.2
—
—
—
0
0
109
705
1.59
4.82
7.6
6.7
24.94
24.90
mmol/l
0.05
109
700
41
196
2.13
4.80
3.1
2.1
—
—
—
0
0
87
532
1.68
4.80
5.7
4.2
—
—
—
0
0
103
660
1.61
4.74
8.2
8.4
24.65
24.46
mmol/l
0.29
98
636
48
247
1.98
4.63
1.1
1.2
—
—
—
0
0
895
8153
1.29
4.60
4.9
4.3
—
—
—
0
0
40
196
2.07
4.42
1.8
1.5
—
—
—
0
0
52
280
1.89
4.41
6.1
4.7
2.20
2.74
mmol/l
0.77
39
194
52
281
1.88
4.37
6.1
4.7
8.56
8.32
kpa
0.42
52
276
52
281
1.88
4.37
6.1
4.8
4.98
5.08
kpa
0.58
52
276
127
873
1.50
4.30
4.6
4.4
—
—
—
0
0
10
16
6.29
4.29
1.0
1.1
—
—
—
0
0
136
950
1.48
4.26
6.1
4.3
—
—
—
0
0
13
29
4.52
4.25
1.1
1.1
1741.00
1761.59
miu/ml
0.02
13
29
10
17
5.92
4.13
1.4
1.0
—
—
—
0
0
43
223
1.96
4.09
4.5
2.6
—
—
—
0
0
359
2954
1.29
4.07
2.6
2.4
—
—
—
0
0
123
853
1.49
4.00
1.5
1.4
—
—
—
0
0
312
2526
1.31
3.99
7.3
4.6
1.01
1.02
kg/l
1.08
32
391
56
320
1.78
3.97
4.2
2.7
—
—
—
0
0
39
199
1.99
3.90
2.4
2.6
—
—
—
0
0
62
368
1.72
3.87
3.8
3.3
0.86
0.82
nmol/l
0.20
50
288
25
107
2.36
3.84
1.2
1.2
—
—
—
0
0
9
16
5.65
3.66
1.0
1.1
—
—
—
0
0
43
233
1.87
3.63
1.6
1.5
—
—
—
0
0
18
68
2.67
3.57
1.1
1.4
—
—
—
0
0
450
3861
1.25
3.54
2.8
2.5
—
—
—
0
0
204
1590
1.33
3.40
5.1
4.8
33.90
33.63
%
0.12
156
1024
29
140
2.09
3.39
1.3
1.2
—
—
—
0
0
19
76
2.52
3.38
2.4
2.8
—
—
—
0
0
57
344
1.69
3.38
6.7
4.4
7.42
7.42
ph
0.36
52
302
28
134
2.11
3.35
1.4
1.2
—
—
nmol/l
—
0
0
338
2824
1.26
3.32
1.8
1.8
24908930.50
18585670.20
pmol/l
0.09
273
2276
14
48
2.94
3.30
8.2
4.2
—
—
—
0
0
11
28
3.95
3.29
1.0
1.0
—
—
—
0
0
446
3854
1.23
3.23
3.2
3.1
6.78
6.82
mmol/l
0.07
362
3162
8
15
5.36
3.19
1.3
1.1
—
—
—
0
0
11
29
3.82
3.18
1.7
1.2
42.80
14.32
%
—
5
19
12
35
3.45
3.11
2.1
1.5
—
—
—
0
0
440
3810
1.23
3.10
3.2
3.2
396.30
292.26
mg/l
0.19
274
2363
45
264
1.73
2.99
5.0
4.0
—
—
—
0
0
65
420
1.58
2.98
1.1
1.1
—
135.09
—
0
11
17
69
2.48
2.96
1.2
1.2
—
—
—
0
0
17
71
2.41
2.80
1.9
1.6
52.65
37.17
%
2.81
17
71
9
23
3.93
2.77
1.1
1.6
—
—
—
0
0
17
72
2.38
2.73
2.4
2.4
—
—
—
0
0
97
696
1.42
2.71
1.3
1.3
—
—
—
0
0
28
146
1.94
2.71
3.3
2.9
—
—
—
0
0
71
480
1.51
2.69
4.4
3.6
1.27
1.41
mmol/l
0.97
71
471
186
1485
1.29
2.62
1.2
1.3
—
—
—
0
0
10
30
3.35
2.60
1.0
1.1
—
17.00
%
—
0
5
5
7
7.17
2.55
1.8
1.4
—
—
—
0
0
33
187
1.78
2.50
4.9
2.7
—
—
—
0
0
11
37
2.99
2.49
2.3
2.3
48309.09
39521.76
ug/l
0.62
11
37
11
37
2.99
2.49
1.3
1.1
—
—
—
0
0
11
37
2.99
2.49
1.1
1.3
—
—
—
0
0
9
26
3.48
2.48
1.4
1.2
—
183.00
—
0
6
62
415
1.52
2.48
4.5
3.8
4.00
3.92
mmol/l
0.66
62
409
14
57
2.47
2.45
2.0
1.2
1.20
1.10
nmol/l
—
9
44
23
117
1.98
2.41
1.4
1.5
—
—
—
0
0
5
8
6.27
2.37
1.0
1.3
—
—
—
0
0
7
17
4.13
2.36
1.4
1.5
—
—
—
0
0
80
570
1.43
2.36
1.1
1.2
161.57
132.44
iu/ml
0.22
23
202
8
23
3.49
2.27
1.0
1.1
—
—
—
0
0
111
846
1.34
2.20
7.4
6.3
24.37
24.52
mmol/l
0.18
106
800
176
1428
1.27
2.20
2.9
4.1
8.22
23.56
ug/l
1.34
144
1185
27
151
1.80
2.17
1.1
1.3
29.58
33.60
iu/l
0.26
22
129
6
14
4.30
2.15
1.8
1.5
34.67
47.64
umol/l
—
6
14
26
145
1.81
2.11
3.0
2.8
—
—
—
0
0
450
4026
1.18
2.09
3.9
3.7
15.28
8.42
mg/mmol
1.32
282
2455
90
673
1.36
2.04
10.5
8.7
—
—
—
0
0
61
426
1.45
2.03
1.3
1.2
—
—
—
0
0
8
26
3.09
2.01
1.3
2.5
—
—
—
0
0
9
32
2.82
2.00
1.4
1.8
—
—
—
0
0
114
886
1.31
2.00
1.6
1.5
—
—
—
0
0
6
16
3.76
1.93
1.0
1.0
—
—
—
0
0
21
114
1.86
1.87
1.2
1.4
—
—
—
0
0
5
12
4.18
1.82
1.8
1.2
—
—
—
0
0
5
12
4.18
1.82
1.8
1.2
—
—
—
0
0
5
12
4.18
1.82
1.8
1.2
—
—
—
0
0
41
272
1.52
1.78
1.7
2.3
—
—
—
0
0
386
3452
1.17
1.77
5.6
5.5
5.01
3.20
ug/l
0.35
337
3039
6
18
3.34
1.74
10.3
6.3
—
—
—
0
0
35
225
1.57
1.74
2.7
1.9
1.75
1.63
mmol/l
0.35
35
218
39
258
1.53
1.72
1.6
1.3
59.50
60.54
mmol/l
0.08
32
210
5
13
3.86
1.71
13.2
11.2
4.62
6.17
mmol/l
—
5
13
41
276
1.50
1.68
3.1
2.6
15.36
15.77
%
0.28
18
132
25
149
1.69
1.67
1.1
1.3
—
—
—
0
0
341
3038
1.16
1.63
1.7
1.6
1.34
1.32
mmol/l
0.12
278
2486
0
42
0.00
1.52
0.0
1.2
—
15.69
—
0
30
5
15
3.34
1.52
1.8
1.1
88.02
209.63
ng/l
—
5
10
9
38
2.38
1.45
1.6
1.1
—
—
—
0
0
26
391
0.66
1.31
1.2
1.4
—
—
—
0
0
39
276
1.43
1.30
3.0
2.8
1.96
1.73
mg/l
0.73
34
246
12
62
1.94
1.28
1.1
1.4
0.81
1.02
g/l
1.55
12
62
21
130
1.63
1.27
1.2
1.3
—
—
—
0
0
16
93
1.73
1.21
1.1
1.2
—
—
—
0
0
7
142
0.49
1.21
1.0
1.1
—
—
—
0
0
52
394
1.33
1.17
5.7
5.7
1.27
1.32
mmol/l
0.21
42
345
0
35
0.00
1.15
0.0
1.1
—
1.54
—
0
13
8
40
2.01
1.12
3.6
2.6
—
—
—
0
0
19
292
0.65
1.10
5.5
4.0
36.08
27.47
mg/l
0.53
12
187
8
41
1.96
1.09
2.0
2.5
—
—
—
0
0
39
287
1.37
1.07
1.2
1.1
—
—
—
0
0
14
82
1.71
1.05
1.0
1.1
—
—
—
0
0
22
323
0.68
1.03
1.4
1.4
—
—
—
0
0
11
60
1.84
1.03
1.4
1.7
9.34
10.22
mmol/l
0.33
11
60
21
139
1.52
1.00
1.1
1.2
12.88
10.47
u/l
0.34
15
104
286
3131
0.89
0.99
3.1
3.3
—
—
—
0
0
72
586
1.24
0.98
2.0
2.2
12.80
12.27
nmol/l
0.21
61
508
129
1120
1.17
0.91
1.3
1.4
—
—
—
0
0
8
42
1.91
0.88
2.1
1.7
—
—
—
0
0
8
43
1.87
0.87
1.6
1.3
—
—
—
0
0
11
64
1.72
0.86
1.5
1.7
—
—
—
0
0
10
57
1.76
0.83
1.0
1.1
—
—
—
0
0
6
32
1.88
0.82
1.8
1.2
16.00
15.13
pmol/l
—
6
22
13
81
1.61
0.81
3.8
3.0
—
—
—
0
0
67
556
1.22
0.80
5.2
4.4
1.51
1.54
%
0.09
62
522
221
2012
1.12
0.79
3.5
3.3
0.65
0.79
ug/l
3.01
164
1408
0
25
0.00
0.79
0.0
6.4
—
—
—
0
0
82
698
1.19
0.76
4.3
4.0
—
—
—
0
0
66
552
1.21
0.74
5.2
4.5
0.87
0.89
%
0.21
61
519
7
38
1.85
0.73
1.9
2.1
—
—
—
0
0
11
70
1.58
0.65
2.0
1.2
—
—
—
0
0
39
314
1.25
0.64
3.6
3.1
24.01
25.37
mmol/l
1.30
39
306
5
30
1.67
0.61
31.0
25.0
6.54
6.56
ug/l
—
5
25
0
20
0.00
0.60
0.0
1.1
—
0.29
—
0
8
11
72
1.53
0.59
1.3
1.4
1612.82
1714.61
ml
0.22
11
67
6
36
1.67
0.56
16.5
28.5
89.83
112.93
ug/l
—
6
30
293
2760
1.08
0.54
1.3
1.3
—
—
—
0
0
11
74
1.49
0.53
1.5
1.9
—
—
—
0
0
35
288
1.22
0.50
7.0
6.2
11.50
11.13
mmol/l
0.41
30
258
35
288
1.22
0.50
7.0
6.2
103.37
105.27
mmol/l
1.35
30
258
7
45
1.56
0.49
1.0
1.4
1.45
1.57
g/l
—
7
45
11
76
1.45
0.48
3.4
2.3
—
—
—
0
0
7
47
1.49
0.47
1.0
1.2
—
—
—
0
0
19
243
0.78
0.46
2.3
1.6
—
—
—
0
0
5
81
0.62
0.46
1.2
1.2
—
—
—
0
0
19
148
1.29
0.43
1.4
1.5
—
—
—
0
0
27
328
0.82
0.43
1.6
1.3
—
—
—
0
0
5
31
1.62
0.43
1.2
1.5
70.00
81.81
nmol/24h
—
5
31
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
10
70
1.43
0.41
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
—
—
0
0
0
18
0.00
0.40
0.0
4.9
—
—
—
0
0
36
306
1.18
0.40
2.0
2.3
276.70
79.47
ug/min
0.41
18
172
28
233
1.21
0.38
3.0
2.9
—
—
—
0
0
57
505
1.13
0.38
2.6
3.3
76.33
2915.98
u/ml
0.83
45
436
90
820
1.10
0.38
4.0
3.4
—
—
—
0
0
20
245
0.81
0.36
3.2
3.8
30.55
45.86
u/ml
0.73
20
238
851
8652
0.96
0.34
40.3
22.1
327.95
331.00
g/l
19.35
844
8577
8
108
0.74
0.29
1.6
1.4
8.94
10.82
%
—
8
108
8
63
1.27
0.27
1.1
1.6
—
—
—
0
0
19
160
1.19
0.25
1.5
1.6
—
—
—
0
0
15
123
1.22
0.25
1.4
2.0
189.67
210.21
pmol/l
0.48
15
115
14
114
1.23
0.25
1.6
2.3
0.57
2.03
u/field
—
7
34
10
78
1.28
0.24
1.5
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
164.20
156.89
mmol/24h
—
5
38
16
135
1.19
0.21
1.3
1.2
283.91
275.11
mosm/kgh2o
0.64
11
95
0
11
0.00
0.21
0.0
1.3
—
0.03
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
44.60
—
0
5
31
277
1.12
0.21
2.3
2.2
126.74
126.35
g/l
0.04
23
205
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
26
230
1.13
0.20
1.1
1.2
—
—
—
0
0
10
80
1.25
0.20
1.5
1.1
—
—
—
0
0
6
48
1.25
0.20
1.2
1.4
3.63
3.08
mmol/l
—
6
42
31
279
1.11
0.19
3.0
2.8
7.94
7.85
kpa
0.11
31
269
5
68
0.73
0.17
1.0
14.1
—
—
—
0
0
17
149
1.14
0.15
1.1
1.2
—
—
—
0
0
9
83
1.08
0.14
1.0
1.2
—
—
—
0
0
34
367
0.92
0.14
28.6
11.4
—
—
—
0
0
20
221
0.90
0.12
1.4
1.5
0.83
0.85
nmol/l
—
10
177
11
127
0.87
0.12
1.4
1.1
—
—
—
0
0
22
201
1.10
0.11
1.5
1.5
27.97
30.93
g/l
0.58
22
182
10
87
1.15
0.09
1.0
1.2
—
—
—
0
0
5
63
0.79
0.08
1.4
1.7
85.20
85.92
umol/l
—
5
63
10
88
1.14
0.08
1.0
1.2
—
—
—
0
0
10
88
1.14
0.08
1.0
1.2
—
—
—
0
0
7
83
0.84
0.07
1.6
1.4
—
—
—
0
0
9
88
1.02
0.07
1.0
1.2
—
—
—
0
0
8
90
0.89
0.06
1.3
2.7
7.01
7.36
mmol/l
—
8
56
27
259
1.04
0.04
1.1
1.1
—
—
—
0
0
105
1034
1.02
0.04
1.4
1.5
—
—
—
0
0
14
144
0.97
0.00
1.3
1.4
—
—
—
0
0
20
199
1.01
0.00
1.8
2.6
—
—
—
0
0
39
391
1.00
0.00
5.2
5.1
—
—
—
0
0
12
117
1.03
0.00
1.1
1.0
—
—
—
0
0
14
143
0.98
0.00
2.9
4.6
275.78
350.36
umol/l
—
9
124
13
135
0.96
0.00
1.5
1.6
—
—
—
0
0
14
135
1.04
0.00
1.9
2.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.06
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
336.20
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
0.00
1.4
1.6
—
—
—
0
0
6
60
1.00
-0.00
3.8
5.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
—
—
0
0
7
75
0.93
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
176.33
—
0
6
0
7
0.00
-0.00
0.0
3.1
—
—
—
0
0
7
74
0.95
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_TEMPARTERIT and mortality.

Females

Parameter HR [95% CI] p-value
M13_TEMPARTERIT 1.308 [1.18, 1.44] < 0.001
Birth year 0.993 [0.99, 1.0] 0.119

During the follow-up period (1.1.1998 — 31.12.2019), 1563 out of 4350 females with M13_TEMPARTERIT died.

Males

Parameter HR [95% CI] p-value
M13_TEMPARTERIT 1.385 [1.19, 1.61] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 789 out of 2033 males with M13_TEMPARTERIT died.

Mortality risk

Mortality risk for people of age

years, who have M13_TEMPARTERIT.

N-year risk Females Males
1 0.127% 0.275%
5 0.736% 1.533%
10 1.731% 3.506%
15 3.541% 6.783%
20 6.176% 11.54%

Relationships between endpoints

Index endpoint: M13_TEMPARTERIT – Temporal arteritis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data