Giant cell arteritis

M13_GIANTCELL

temporal arteritis: Giant cell arteritis (GCA) is a large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M31.5, M31.6
  • Hospital discharge: ICD-9 4465
  • Cause of death: ICD-10 M31.5, M31.6
  • Cause of death: ICD-9 4465

2 out of 7 registries used, show all original rules.

1551

4. Check minimum number of events

None

1551

5. Include endpoints

1551

6. Filter based on genotype QC (FinnGen only)

1514

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9069 6071 2933
Only index persons 7652 5164 2488
Unadjusted period prevalence (%)
Whole population 0.14 0.17 0.08
Only index persons 0.16 0.19 0.09
Median age at first event (years)
Whole population 72.33 72.72 71.45
Only index persons 71.52 71.93 70.66

-FinnGen-

Key figures

All Female Male
Number of individuals 1514 924 590
Unadjusted period prevalence (%) 0.31 0.33 0.27
Median age at first event (years) 70.27 69.82 70.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1551
Matched controls
15510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
8.7
307.7
531
880
L04AX03
ATC
methotrexate; systemic
10.4
307.7
512
701
M31.6
ICD-10 Finland
Other giant cell arteritis
2621.2
307.7
375
*
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
4503599627370496.0
307.7
1353
5
H02AB06
ATC
prednisolone; systemic
18.9
307.7
1417
5556
PAW37
NOMESCO Finland
Biopsy of temporal artery
1325.1
307.7
583
7
M35.3
ICD-10 Finland
Polymyalgia rheumatica
61.4
307.7
554
139
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
15.8
246.2
223
163
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.0
242.8
1119
4667
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.5
240.6
320
414
M05BA04
ATC
alendronic acid; oral
6.1
221.1
491
1093
R51.80
ICD-10 Finland
Headache
4.9
160.7
458
1233
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
5.7
135.5
285
586
I77.6
ICD-10 Finland
Arteritis, unspecified
230.3
124.7
127
6
R50.9
ICD-10 Finland
Fever, unspecified
3.7
104.1
413
1374
A02BC02
ATC
pantoprazole; systemic
4.3
97.7
1332
9072
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
95.8
91
*
L88
ICPC
Rheumatoid/seropositive arthritis
6.6
91.3
155
256
L04AX01
ATC
azathioprine; systemic
7.1
86.5
137
210
H02AB07
ATC
prednisone; oral
3.1
70.5
359
1364
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
70.1
981
6177
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
33.1
69.8
45
14
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.2
64.1
189
501
TPX00
NOMESCO Finland
Biopsy of artery or vein
150.5
55.2
58
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.1
53.4
82
121
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.7
53.2
103
192
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
52.5
306
1236
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
17.0
51.5
43
26
N01
ICPC
Headache
3.3
50.4
207
683
L04AC07
ATC
tocilizumab; parenteral
89.7
47.1
52
6
H53.1
ICD-10 Finland
Subjective visual disturbances
3.5
47.0
173
532
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
11.0
46.3
50
47
A10AC01
ATC
insulin (human); parenteral
3.2
45.7
199
679
L04AA13
ATC
[U] leflunomide
5.9
44.7
82
145
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
44.5
384
1863
M13.9
ICD-10 Finland
Arthritis, unspecified
3.4
43.2
169
539
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.2
42.5
117
293
G44.2
ICD-10 Finland
Tension-type headache
2.7
42.2
270
1135
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
418.3
41.3
41
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.7
40.3
76
138
AA1AD
NOMESCO Finland
CT of head and brain
2.1
40.1
594
3562
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
40.1
285
1259
H57.1
ICD-10 Finland
Ocular pain
4.7
38.9
93
208
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
38.1
586
3548
M05BA07
ATC
risedronic acid; oral
3.8
37.2
121
341
M31.3
ICD-10 Finland
Wegener granulomatosis
376.1
37.2
37
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
365.5
36.1
36
*
P01BA02
ATC
hydroxychloroquine; oral
3.0
35.5
168
599
ZX120
NOMESCO Finland
Intravenous
2.7
35.3
214
871
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
34.0
668
4361
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
33.2
229
992
L01BA01
ATC
methotrexate; systemic
3.9
30.5
94
255
A01
ICPC
Pain general/multiple sites
2.5
30.3
209
903
J01DB01
ATC
cefalexin; oral
2.2
29.6
1282
10645
M35.5
ICD-10 Finland
Multifocal fibrosclerosis
+∞
29.3
28
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
29.2
506
3131
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.2
29.2
121
398
H34.1
ICD-10 Finland
Central retinal artery occlusion
9.6
28.9
34
36
M05BX04
ATC
denosumab; parenteral
2.6
28.5
173
702
4465A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Giant cell arteritis
+∞
27.2
26
*
M25.5
ICD-10 Finland
Pain in joint
1.9
26.2
491
3097
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
25.7
342
1923
N02BE01
ATC
paracetamol; systemic, rectal
2.7
25.7
1424
12543
M79.6
ICD-10 Finland
Pain in limb
1.8
25.4
693
4876
R51.81
ICD-10 Finland
Facial pain NOS
4.4
25.2
64
150
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
25.1
405
2428
R51
ICD-10 Finland
Headache
3.3
24.7
98
314
R06.0
ICD-10 Finland
Dyspnoea
1.8
24.3
507
3288
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.5
24.2
84
247
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
23.9
208
992
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
23.7
652
4572
L95
ICPC
Osteoporosis
3.0
23.6
111
393
R52.9
ICD-10 Finland
Pain, unspecified
2.3
23.4
185
847
UJF32
NOMESCO Finland
Coloscopy
1.8
23.0
486
3154
N02AX02
ATC
tramadol; systemic, rectal
1.7
23.0
724
5256
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
23.0
215
1056
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
23.0
779
5769
N03AX16
ATC
[U] pregabalin
1.8
22.8
413
2559
A03
ICPC
Fever
2.2
22.2
221
1112
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
22.1
332
1936
A02BC05
ATC
esomeprazole; systemic
1.7
22.0
672
4820
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
21.8
194
932
M79.1
ICD-10 Finland
Myalgia
2.1
21.8
240
1254
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
21.6
139
579
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
21.5
568
3912
N03AX12
ATC
[U] gabapentin; oral
1.9
21.2
298
1696
R53
ICD-10 Finland
Malaise and fatigue
1.8
21.2
416
2632
XCK00
NOMESCO Finland
Perimetry
2.5
21.0
146
630
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
21.0
157
701
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
20.8
313
1823
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
20.5
747
5577
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
20.4
512
3466
J01FF01
ATC
clindamycin; systemic
1.7
19.9
438
2857
R02
ICPC
Shortness of breath/dyspnoea
2.0
19.8
250
1370
S18
ICPC
Laceration/cut
1.6
19.8
764
5770
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.3
19.7
75
234
JN4AD
NOMESCO Finland
Body CT examination
2.1
19.2
199
1015
J01MA02
ATC
ciprofloxacin; systemic
1.6
19.1
652
4762
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
19.0
228
1226
J01MA14
ATC
moxifloxacin; systemic
2.2
18.9
169
813
H15.1
ICD-10 Finland
Episcleritis
6.4
18.9
31
49
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
18.9
123
515
5BA08, ,
NOMESCO Finland
8.2
18.8
25
31
M31.4
ICD-10 Finland
Aortic arch syndrome [Takayasu]
+∞
18.8
18
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
18.8
18
*
L04AA06
ATC
mycophenolic acid; systemic
5.7
18.7
35
63
A10AB05
ATC
insulin aspart; parenteral
2.3
18.6
145
658
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
18.6
163
778
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
18.5
266
1522
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
18.3
146
669
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
4.8
18.3
41
87
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
18.2
539
3787
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.8
18.2
327
2004
C07AB07
ATC
bisoprolol; oral
1.6
18.1
895
7117
TAB00
NOMESCO Finland
Lumbar puncture
3.0
18.1
84
295
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.3
17.8
146
677
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.1
17.6
73
240
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
17.6
194
1010
L17
ICPC
Foot/toe symptom/complaint
1.7
17.6
472
3228
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
17.6
183
933
J01AA02
ATC
doxycycline; systemic
1.7
17.5
1200
10308
H53.2
ICD-10 Finland
Diplopia
3.1
17.5
76
257
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.9
17.5
31
53
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
17.3
367
2357
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
17.1
694
5241
R03AC02
ATC
salbutamol; inhalant
1.6
17.1
805
6294
J01CA04
ATC
amoxicillin; systemic
1.7
17.1
1186
10180
H02AB09
ATC
hydrocortisone; systemic
3.8
17.1
52
140
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
16.9
152
732
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
16.8
142
666
R20.2
ICD-10 Finland
Paraesthesia of skin
2.5
16.8
112
474
M03BX02
ATC
tizanidine; oral
1.6
16.7
856
6807
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
16.7
226
1264
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
16.5
601
4414
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
16.3
269
1601
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
16.3
214
1185
C03CA01
ATC
furosemide; systemic
1.6
16.1
624
4644
A02BC01
ATC
omeprazole; systemic
1.6
16.0
468
3258
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
60.7
15.8
18
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.4
15.5
114
504
M30.0
ICD-10 Finland
Polyarteritis nodosa
161.6
15.5
16
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.5
15.4
98
405
L01
ICPC
Neck symptom/complaint
1.8
15.2
237
1384
R42
ICD-10 Finland
Dizziness and giddiness
1.6
15.1
409
2785
M79.7
ICD-10 Finland
Fibromyalgia
3.2
15.0
59
188
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
15.0
991
8253
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
15.0
413
2826
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
15.0
153
774
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
14.8
395
2680
M05BA06
ATC
ibandronic acid; systemic
3.1
14.8
63
211
J01FA10
ATC
azithromycin; systemic
1.5
14.8
755
5939
E0000UV, ,
ATC
1.5
14.6
611
4599
M54.5
ICD-10 Finland
Low back pain
1.6
14.6
519
3768
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
6.4
14.6
24
38
L28
ICPC
Limited function/disability (L)
1.7
14.6
351
2319
A46
ICD-10 Finland
Erysipelas
1.8
14.5
260
1583
H53.4
ICD-10 Finland
Visual field defects
3.5
14.5
49
142
R05
ICD-10 Finland
Cough
1.7
14.5
333
2173
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
14.5
167
883
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.9
14.4
70
253
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
14.2
221
1290
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
14.2
485
3485
H47.1
ICD-10 Finland
Papilloedema, unspecified
11.0
14.0
26
24
Z71.8
ICD-10 Finland
Other specified counselling
1.6
14.0
425
2970
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
13.9
661
5096
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.1
13.9
143
724
A04
ICPC
Weakness/tiredness general
1.8
13.9
258
1585
J01FA06
ATC
roxithromycin; oral
1.5
13.9
612
4643
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.3
13.8
106
478
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
13.8
205
1179
N05CF01
ATC
zopiclone; oral
1.5
13.8
543
4022
WZC30
NOMESCO Finland
Teaching
1.7
13.7
259
1599
H02AB04
ATC
methylprednisolone; systemic
1.8
13.7
238
1436
A02BC03
ATC
lansoprazole; oral
1.6
13.7
477
3438
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.9
13.6
40
105
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.4
13.5
97
424
SPAT1263
SPAT
Sampling
1.5
13.5
643
4952
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.6
13.4
76
297
A07EC01
ATC
sulfasalazine; oral, rectal
2.1
13.3
128
632
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
13.3
289
1853
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
13.2
299
1939
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.1
13.2
135
683
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
13.0
152
807
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.5
13.0
44
128
J01MA12
ATC
levofloxacin; systemic
1.6
12.9
313
2064
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
12.9
354
2407
CS494
NOMESCO Finland
Other visual field testing
2.9
12.9
59
206
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.0
12.8
142
739
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
12.8
410
2890
L18
ICPC
Muscle pain
2.6
12.8
74
293
SPAT1153
SPAT
Removal of sutures
1.5
12.7
528
3941
G50.1
ICD-10 Finland
Atypical facial pain
3.6
12.6
41
116
R03DC03
ATC
montelukast; oral
1.7
12.6
230
1406
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.0
12.4
54
183
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
12.4
947
7970
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
12.2
193
1130
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
12.2
235
1457
R52.2
ICD-10 Finland
Other chronic pain
2.6
12.2
71
282
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
12.2
151
818
R03BB04
ATC
tiotropium bromide; inhalant
1.8
12.1
189
1102
Z3231
NOMESCO Finland
Registered nurse
1.5
12.1
427
3072
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
11.9
268
1730
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
11.9
277
1804
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
11.9
288
1895
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
11.9
244
1538
B01AC04
ATC
clopidogrel; oral
1.6
11.9
315
2120
TNG10
NOMESCO Finland
Puncture of knee
4.5
11.7
28
63
R63.4
ICD-10 Finland
Abnormal weight loss
2.4
11.5
76
320
J02AC01
ATC
fluconazole; systemic
1.5
11.5
524
3966
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
11.5
11
*
4AC07, ,
NOMESCO Finland
120.9
11.4
12
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
120.9
11.4
12
*
UJF92
NOMESCO Finland
Capsular endoscopy
3.4
11.4
40
119
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.4
11.4
41
124
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
11.4
611
4774
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
9.0
11.3
23
26
G45.3
ICD-10 Finland
Amaurosis fugax
3.0
11.2
48
162
PD5AD
NOMESCO Finland
CT of aorta
3.0
11.2
48
162
L03
ICPC
Low back symptom/complaint
1.5
11.1
396
2844
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
11.1
84
377
R05
ICPC
Cough
1.6
11.0
350
2451
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.5
11.0
37
107
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.2
11.0
42
132
C08CA01
ATC
amlodipine; oral
1.4
11.0
688
5522
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.7
11.0
59
225
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.0
11.0
124
650
R74
ICPC
Upper respiratory infection acute
1.6
11.0
332
2301
N02BF01
ATC
gabapentin; oral
1.9
10.9
135
730
L99
ICPC
Musculoskeletal disease other
3.2
10.9
42
133
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
10.8
843
7035
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
10.8
403
2922
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
10.8
301
2046
R60.0
ICD-10 Finland
Localized oedema
1.7
10.8
220
1383
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
10.7
119
620
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
10.6
155
884
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
10.4
10
*
4AC0X, ,
NOMESCO Finland
+∞
10.4
10
*
J05AB01
ATC
aciclovir; systemic
1.6
10.4
320
2222
H34.2
ICD-10 Finland
Other retinal artery occlusions
5.5
10.4
20
37
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
10.4
192
1174
R55
ICD-10 Finland
Syncope and collapse
1.7
10.4
200
1237
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
7.8
10.4
23
30
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.3
10.4
80
362
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
12.1
10.3
18
15
PA6AD
NOMESCO Finland
CT of neck arteries
2.7
10.3
56
215
XF402
NOMESCO Finland
ECG with work load test
1.7
10.3
187
1138
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
3.4
10.3
37
112
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
10.3
273
1833
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
10.2
188
1149
NXL00
NOMESCO Finland
Biopsy of muscle
13.2
10.2
17
13
H26.3
ICD-10 Finland
Drug-induced cataract
8.0
10.1
22
28
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.3
10.1
74
328
L01AA01
ATC
cyclophosphamide; systemic
8.5
10.1
21
25
L08
ICPC
Shoulder symptom/complaint
1.5
10.1
327
2298
F29
ICPC
Eye symptom/complaint other
1.8
10.0
144
817
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
10.0
320
2239
JN6JR
NOMESCO Finland
Extensive PET-CT of whole body metabolism (crown to foot)
40.3
10.0
12
*
R21
ICPC
Throat symptom/complaint
1.7
9.9
213
1355
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
9.9
272
1840
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.0
9.8
43
147
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
9.8
100
506
N06AX21
ATC
duloxetine; oral
1.8
9.8
165
984
GD1AD
NOMESCO Finland
Thorax CT examination
2.0
9.7
100
507
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.8
9.7
154
901
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.6
9.7
57
228
SPAT1301
SPAT
No procedures
1.4
9.7
497
3823
S97
ICPC
Chronic ulcer skin
1.9
9.7
116
621
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
5.3
9.6
19
36
SPAT1260
SPAT
Consultation of another employee
1.6
9.6
274
1867
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.7
9.6
165
988
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
9.6
108
566
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
9.6
115
616
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
9.6
106
552
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.9
9.6
129
718
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
9.6
598
4764
R03BA05
ATC
fluticasone; inhalant
1.6
9.6
255
1712
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
9.5
259
1747
Z01.2
ICD-10 Finland
Dental examination
1.4
9.5
565
4461
M10.9
ICD-10 Finland
Gout, unspecified
1.9
9.5
122
669
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.4
9.5
34
103
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
9.4
9
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.5
9.4
58
238
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.3
711
5855
H92.0
ICD-10 Finland
Otalgia
2.2
9.3
80
379
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.7
9.3
29
80
JN4BD
NOMESCO Finland
Extensive body CT
1.7
9.3
184
1147
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
9.2
124
690
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
9.2
97
497
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
9.2
80
381
B01AF02
ATC
apixaban; oral
1.6
9.1
242
1621
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.4
9.1
64
278
C08CA05
ATC
nifedipine; systemic
1.9
9.1
110
591
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.4
9.1
61
260
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
9.1
310
2197
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.0
9.0
93
472
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
9.0
572
4556
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
9.0
281
1954
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.6
9.0
29
82
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.9
9.0
105
558
R01AD08
ATC
fluticasone; nasal
1.5
8.9
353
2578
B02.9
ICD-10 Finland
Zoster without complication
1.9
8.9
117
646
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
2.6
8.9
49
190
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
8.9
496
3862
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
8.9
121
676
L20
ICPC
Joint symptom/complaint NOS
2.4
8.8
59
251
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
8.7
8.8
18
21
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
8.8
223
1478
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
8.8
106
569
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
8.8
96
498
J31.0
ICD-10 Finland
Chronic rhinitis
1.9
8.8
108
584
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
8.7
196
1261
R07.0
ICD-10 Finland
Pain in throat
2.1
8.7
77
369
J01FA09
ATC
clarithromycin; systemic
1.4
8.7
404
3041
M48.0
ICD-10 Finland
Spinal stenosis
1.6
8.7
226
1508
ZXA00
NOMESCO Finland
Right side
1.4
8.6
439
3358
SPAT1310
SPAT
Counselling related to known health issue
1.4
8.6
466
3604
R01AD12
ATC
fluticasone furoate; nasal
1.5
8.6
350
2567
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
8.6
81
398
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
8.6
194
1250
R06AE07
ATC
cetirizine; oral
1.4
8.6
575
4614
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4.1
8.5
23
57
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.4
8.5
56
237
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
8.5
358
2644
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
8.5
206
1351
Z00.0
ICD-10 Finland
General medical examination
1.5
8.4
284
2006
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.6
8.4
47
184
318
Kela drug reimbursment
Teriparatide
4.9
8.4
18
37
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.8
8.4
121
689
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
8.3
8
*
4AC0L, ,
NOMESCO Finland
+∞
8.3
8
*
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
8.3
8
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
8.3
174
1100
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
4.1
8.3
22
54
G43.9
ICD-10 Finland
Migraine, unspecified
2.4
8.3
56
240
R01AD09
ATC
mometasone; nasal
1.4
8.3
562
4514
R07.3
ICD-10 Finland
Other chest pain
1.7
8.2
162
1007
R04.2
ICD-10 Finland
Haemoptysis
2.3
8.2
61
272
PA7BD
NOMESCO Finland
CT angiography of neck and brain
2.9
8.2
37
129
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.8
8.2
125
724
Z01.9
ICD-10 Finland
Special examination, unspecified
1.9
8.2
95
504
D01
ICPC
Abdominal pain/cramps general
1.7
8.2
153
939
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
8.1
403
3063
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
8.1
97
519
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.8
8.1
24
64
M05.2
ICD-10 Finland
Rheumatoid vasculitis
33.5
8.1
10
*
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
3.7
8.0
25
69
R03BA02
ATC
budesonide; inhalant
1.5
8.0
250
1735
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
8.0
54
231
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
8.0
114
647
A01AB10
ATC
natamycin; local oral
2.5
8.0
49
201
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.4
8.0
55
238
H29
ICPC
Ear symptom/complaint other
1.6
7.9
176
1128
A07AA02
ATC
nystatin; oral
1.9
7.9
106
589
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
7.9
147
900
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.9
265
1867
A11
ICPC
Chest pain NOS
1.7
7.9
140
846
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
4.7
7.9
18
39
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.8
7.9
37
132
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
7.9
325
2387
XG410
NOMESCO Finland
Flow-volume spirometry
2.2
7.8
65
304
ZXE00
NOMESCO Finland
One hour or less
1.4
7.8
547
4405
TGC00
NOMESCO Finland
Bronchial lavation
2.6
7.8
45
179
R10.0
ICD-10 Finland
Acute abdomen
2.5
7.8
46
185
PG1AE
NOMESCO Finland
Ultrasound examination of artery not elsewher classified
7.0
7.8
18
26
J20
ICD-10 Finland
Acute bronchitis
1.7
7.8
146
897
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
7.8
351
2622
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
7.7
165
1047
K07.60
ICD-10 Finland
Snapping jaw
2.3
7.7
55
242
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
7.6
132
793
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.6
282
2027
PAA99
NOMESCO Finland
Exploration of other arterial branch originating from aortic arch arteries
25.1
7.6
10
*
H26.4
ICD-10 Finland
After-cataract
1.6
7.6
206
1387
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
7.5
234
1621
B01AA03
ATC
warfarin; systemic
1.4
7.5
346
2590
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
7.5
156
983
M01AH02
ATC
rofecoxib; oral
1.5
7.5
217
1480
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.5
237
1648
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.7
7.5
40
153
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
4.3
7.5
19
45
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
3.7
7.5
23
63
Z2221
NOMESCO Finland
Medical doctor
1.4
7.4
383
2925
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.4
509
4077
SFA10
NOMESCO Finland
One-surface restoration
1.3
7.4
690
5793
C08CA13
ATC
lercanidipine; oral
1.5
7.4
252
1780
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
1.8
7.4
112
647
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
7.4
67
325
R11
ICD-10 Finland
Nausea and vomiting
1.7
7.4
135
823
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.9
7.4
86
457
UKC02
NOMESCO Finland
Cystoscopy
1.5
7.4
256
1815
N06AA09
ATC
amitriptyline; systemic
1.6
7.3
160
1021
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
7.3
84
444
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.9
7.3
84
444
C10AA05
ATC
atorvastatin; oral
1.3
7.3
685
5752
XW000
NOMESCO Finland
Bone marrow biopsy
2.0
7.3
75
381
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
7.3
7
*
L04AK01
ATC
leflunomide; oral
6.9
7.3
17
25
M01AE02
ATC
naproxen; oral, rectal
1.3
7.2
745
6340
R13
ICD-10 Finland
Dysphagia
1.8
7.2
114
667
F01
ICPC
Eye pain
2.6
7.2
41
162
K04.1
ICD-10 Finland
Necrosis of pulp
1.7
7.2
125
752
G50.0
ICD-10 Finland
Trigeminal neuralgia
2.7
7.1
36
134
SPAT1081
SPAT
Cardiorespiratory global assessment
1.8
7.1
100
565
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.9
7.1
32
112
H46
ICD-10 Finland
Optic neuritis
6.1
7.1
18
30
R96
ICPC
Asthma
1.6
7.0
147
929
M01AH03
ATC
valdecoxib; oral
1.9
7.0
92
509
A01AB09
ATC
miconazole; local oral
1.7
7.0
140
875
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.9
470
3750
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
5.5
6.9
19
35
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.2
6.9
54
247
K30
ICD-10 Finland
Functional dyspepsia
1.6
6.9
152
973
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.8
706
5994
J37.0
ICD-10 Finland
Chronic laryngitis
2.3
6.8
51
229
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
6.8
51
229
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
6.8
87
477
K08.80
ICD-10 Finland
Toothache NOS
1.8
6.8
93
521
J05AB11
ATC
valaciclovir; oral
1.5
6.8
203
1394
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.1
6.8
66
329
R03BA01
ATC
beclometasone; inhalant
1.5
6.8
199
1361
UDM02
NOMESCO Finland
Sinoscopy
2.7
6.8
34
126
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
6.8
191
1295
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.8
439
3477
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.7
6.8
21
58
J01CF05
ATC
flucloxacillin; systemic
1.9
6.7
85
464
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.6
6.7
37
144
N06AX11
ATC
mirtazapine; oral
1.4
6.7
477
3830
G44.8
ICD-10 Finland
Other specified headache syndromes
3.4
6.7
23
68
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.7
411
3226
WVA20
NOMESCO Finland
Medicine administration
2.4
6.7
44
187
R60.9
ICD-10 Finland
Oedema, unspecified
1.8
6.6
91
511
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.7
6.6
133
832
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.9
6.6
86
475
L29
ICPC
Musculoskeletal sympt/complt other
1.7
6.6
126
778
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
6.6
387
3015
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
2.6
6.6
35
134
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.6
705
6007
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.6
544
4468
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
3.8
6.5
19
50
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
6.5
146
938
H25.8
ICD-10 Finland
Other senile cataract
1.5
6.5
217
1524
D07AC01
ATC
betamethasone; topical
1.3
6.5
497
4031
XF404
NOMESCO Finland
Ambulatory ECG
1.6
6.5
143
915
E000006, ,
ATC
1.8
6.5
101
589
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
3.7
6.5
20
55
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.5
614
5139
H05AA02
ATC
teriparatide; parenteral
5.3
6.5
18
34
A02BA02
ATC
ranitidine; systemic
1.4
6.5
311
2342
ZXA10
NOMESCO Finland
Bilateral
1.4
6.5
295
2201
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.2
6.5
25
80
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
6.4
106
628
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.3
6.4
47
209
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
70.1
6.4
7
*
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
2.4
6.4
43
184
E000002, ,
ATC
1.6
6.4
130
815
L19
ICPC
Muscle symptom/complaint NOS
2.4
6.4
42
178
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.8
6.4
88
494
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
6.4
85
472
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
6.4
126
784
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
6.4
256
1864
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.6
6.4
35
136
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
2.4
6.4
40
166
SPAT1262
SPAT
Handing over of treatment supplies
1.4
6.4
273
2012
L07
ICPC
Jaw symptom/complaint
3.8
6.4
19
51
N03
ICPC
Pain face
4.1
6.4
17
42
WX892
NOMESCO Finland
Monitored bed care
1.7
6.4
118
723
R04.0
ICD-10 Finland
Epistaxis
1.7
6.3
125
778
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.3
447
3580
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.0
6.3
64
324
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
3.1
6.3
25
81
I73.0
ICD-10 Finland
Raynaud syndrome
3.6
6.3
20
56
ED1AA
NOMESCO Finland
Mandibular X-ray examination
6.0
6.3
16
27
K11.2
ICD-10 Finland
Sialoadenitis
2.3
6.3
46
205
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.3
399
3144
SFA30
NOMESCO Finland
Three-surface restoration
1.3
6.3
529
4350
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
6.3
6
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
6.3
6
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.6
6.2
159
1054
7901A
ICD-9 Finland
Nonspecific findings on examination of blood, Elevated sedimentation rate
26.8
6.2
8
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
6.2
151
990
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
3.7
6.2
19
52
ZZH40
NOMESCO Finland
Substitute of bone
3.7
6.2
19
52
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
6.2
272
2014
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.2
239
1728
L04AA01
ATC
[U] ciclosporin
3.2
6.2
24
77
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.7
6.2
114
698
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.3
6.1
46
207
L60.0
ICD-10 Finland
Ingrowing nail
1.9
6.1
70
370
M01AH01
ATC
celecoxib; oral
1.4
6.1
269
1992
R01AD01
ATC
beclometasone; nasal
1.5
6.1
197
1374
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.8
6.1
18
48
H53.8
ICD-10 Finland
Other visual disturbances
3.0
6.1
25
83
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
6.1
158
1052
J01DA01
ATC
[U] cefalexin
1.3
6.1
866
7637
SPAT1312
SPAT
General health counselling
1.3
6.0
423
3380
SPAT1211
SPAT
Application of soft bandage
1.6
6.0
131
836
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.3
6.0
44
196
M01AH05
ATC
etoricoxib; oral
1.3
6.0
798
6967
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
5.2
6.0
17
33
M45
ICD-10 Finland
Ankylosing spondylitis
2.8
6.0
28
100
A41.9
ICD-10 Finland
Sepsis, unspecified
2.0
6.0
59
296

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
332
368
11.21
282.50
2.1
1.4
232.73
166.67
titre
0.22
22
12
598
1336
6.66
274.11
1.5
1.2
504.31
399.72
titre
0.69
130
287
1153
5789
4.86
175.04
12.4
5.8
—
—
—
0
0
1183
6191
4.84
166.14
11.9
5.2
0.65
0.61
e9/l
5.72
1080
5237
1184
6204
4.84
165.89
11.9
5.2
0.04
0.04
e9/l
0.99
1079
5257
1190
6331
4.78
161.35
12.0
5.2
1.86
1.94
e9/l
0.55
1103
5490
1199
6418
4.83
161.11
12.1
5.4
0.16
0.19
e9/l
11.09
1100
5521
199
267
8.40
142.82
1.7
1.2
0.26
0.24
g/l
0.72
186
248
1080
5661
3.99
141.84
12.3
5.4
0.59
0.66
%
4.18
1046
5213
202
280
8.14
140.98
1.7
1.2
1.31
1.20
g/l
3.24
190
262
1096
5843
3.99
139.31
12.8
5.7
8.34
8.86
%
6.28
1063
5385
1089
5819
3.93
137.03
12.4
5.4
2.06
2.82
%
29.94
1056
5362
163
181
9.95
135.73
1.8
1.1
—
—
—
0
0
1097
5956
3.88
133.15
12.6
5.6
24.06
26.61
%
12.72
1064
5506
381
1017
4.64
132.95
1.7
2.7
—
—
—
0
0
1083
5852
3.82
131.93
12.2
5.4
62.20
58.05
%
23.03
1048
5403
536
1857
3.88
130.60
1.4
1.2
36.46
42.78
iu/ml
0.30
164
585
517
1774
3.87
127.34
1.4
1.2
6.91
14.43
u/ml
2.02
170
622
1222
7352
4.12
121.85
14.4
8.7
5.05
4.18
e9/l
29.40
1122
6352
1009
5518
3.37
113.82
2.9
2.2
82.42
79.97
nmol/l
1.81
943
4776
201
348
6.49
113.60
1.4
1.1
0.16
1.07
u/ml
0.86
15
31
403
1249
4.01
113.57
1.7
2.9
65.22
66.11
g/l
1.36
364
1122
1182
7176
3.72
111.03
7.9
6.5
1.22
1.22
mmol/l
0.92
1048
6067
831
4260
3.05
100.88
2.7
2.1
126.35
229.53
u/l
4.43
790
3956
1083
6555
3.16
95.25
6.5
5.7
1.21
1.21
mmol/l
0.29
1043
5903
354
1136
3.74
93.27
2.2
2.1
343.50
380.81
nmol/l
2.89
322
1024
1357
9561
4.35
89.94
15.0
3.9
17.81
14.31
mm/h
10.05
1313
8680
316
990
3.75
85.75
7.1
3.5
0.47
0.66
%
1.39
151
345
333
1098
3.59
83.50
7.5
3.6
0.92
0.91
%
0.02
161
404
335
1115
3.56
82.74
1.5
1.5
—
—
—
0
0
288
875
3.81
81.49
2.3
2.8
10.17
10.87
g/l
1.19
264
785
315
1031
3.58
79.61
7.8
3.7
0.03
0.10
%
2.90
142
339
299
953
3.65
78.62
1.4
1.5
—
—
—
0
0
300
963
3.62
78.00
8.0
3.7
0.04
0.37
%
0.54
129
279
221
576
4.31
77.17
1.5
2.8
3.84
3.60
g/l
2.05
198
513
221
577
4.30
76.98
1.5
2.7
8.79
7.43
g/l
14.74
198
513
210
536
4.37
75.30
1.5
2.8
3.72
2.96
g/l
11.74
186
473
305
1014
3.50
74.93
1.4
1.5
—
—
—
0
0
745
4076
2.59
72.60
5.1
4.2
—
—
—
0
0
239
692
3.90
72.03
1.5
1.8
1.19
1.47
g/l
0.97
219
615
206
540
4.25
71.17
1.5
2.8
9.52
10.43
g/l
1.96
180
475
1264
9103
3.10
67.92
8.3
4.6
—
—
—
0
0
218
616
3.95
67.83
1.2
1.3
—
—
—
0
0
754
4304
2.46
65.02
4.4
3.9
7.40
7.40
ph
0.18
162
812
175
453
4.23
61.20
1.5
2.7
33.26
37.48
g/l
11.73
149
390
1344
10259
3.32
60.31
13.0
7.5
73.17
80.30
u/l
8.72
1314
9539
116
225
5.49
57.45
1.4
1.1
8.24
3.31
u/ml
0.90
17
14
226
733
3.44
56.84
2.6
2.5
31.26
26.17
au/ml
—
8
37
117
231
5.40
56.81
1.5
1.1
14.40
3.53
u/ml
1.02
20
28
137
313
4.70
56.10
1.6
2.0
11.05
12.47
mg/l
1.24
126
284
208
648
3.55
55.65
1.4
1.4
28.17
54.21
au/ml
—
6
38
966
6437
2.33
54.94
6.1
4.1
0.00
0.01
estimate
0.80
234
1139
955
6366
2.30
53.78
6.1
4.1
0.00
0.00
estimate
0.75
252
1255
866
5547
2.27
53.68
17.7
9.8
0.00
0.00
e9/l
0.36
738
4502
175
499
3.83
53.32
1.6
3.7
1.85
1.64
ratio
0.12
16
36
92
157
6.17
52.07
1.3
1.6
0.78
0.80
g/l
0.04
67
120
949
6364
2.27
51.89
7.7
5.5
0.00
0.00
estimate
-0.00
240
1152
176
514
3.73
51.75
1.7
3.7
30.55
80.94
mg/l
1.24
144
422
176
515
3.73
51.60
1.7
3.7
38.70
61.85
mg/l
1.15
143
421
139
345
4.33
51.18
1.3
1.7
—
—
—
0
0
191
596
3.51
50.81
1.7
1.9
1.48
1.90
ug/l
0.26
163
513
1115
8049
2.37
50.33
5.7
4.7
6.73
6.84
mmol/l
1.11
1071
7581
622
3656
2.17
45.60
2.7
2.2
3.13
3.14
mg/l
0.05
540
3063
61
81
7.80
43.50
1.4
1.1
269.23
152.86
titre
0.34
13
14
51
54
9.73
43.48
1.1
1.1
5.20
8.25
u/l
0.50
36
44
136
379
3.84
42.61
1.6
4.0
—
—
—
0
0
409
2098
2.29
41.30
1.5
1.5
2.46
2.59
g/l
0.54
279
1177
418
2181
2.25
40.40
2.8
2.4
10.96
12.17
umol/l
2.79
384
2014
1174
9020
2.24
40.22
6.7
5.1
224.71
2396.43
e6/l
—
7
151
745
4862
2.02
39.70
5.2
3.8
83.35
118.42
e6/l
0.72
575
3525
774
5161
2.00
38.37
3.6
2.7
178.88
140.50
ug/l
2.28
705
4642
59
87
7.01
38.35
1.2
1.5
0.33
0.40
g/l
0.59
46
61
59
87
7.01
38.35
1.2
1.5
2.69
2.70
g/l
0.02
47
62
59
87
7.01
38.35
1.2
1.5
5.95
7.38
g/l
1.30
46
61
761
5078
1.98
37.30
5.1
3.8
5.64
5.82
ph
0.49
18
229
388
2024
2.22
37.11
2.8
2.4
2.23
2.29
g/l
1.27
354
1854
664
4239
1.99
36.87
4.1
3.3
32.50
74.68
e6/l
1.77
552
3279
371
1908
2.24
36.70
2.9
2.4
19.48
21.65
%
2.03
313
1616
68
122
5.78
36.49
1.4
1.2
—
—
—
0
0
624
3916
1.99
36.24
3.9
3.2
0.30
0.53
e6/l
3.15
512
3006
979
7166
1.99
36.18
5.8
6.2
10.38
11.78
umol/l
3.02
940
6778
605
3759
2.00
36.13
3.9
3.2
—
—
—
0
0
58
90
6.66
35.95
1.2
1.5
—
—
—
0
0
657
4217
1.97
35.57
2.8
2.5
56.35
60.27
u/l
0.67
610
3849
76
167
4.73
32.47
1.4
1.1
64.83
12.97
u/ml
—
6
14
940
6940
1.90
32.03
20.9
17.7
1.29
1.32
inr
0.45
265
1910
867
6259
1.87
31.45
5.1
4.6
33.39
34.79
g/l
10.66
811
5790
529
3274
1.93
30.87
9.5
6.5
—
—
—
0
0
333
1750
2.15
30.60
2.3
2.4
1.88
1.82
%
0.43
302
1533
544
3407
1.92
30.57
2.8
2.8
3352.83
8040.54
umol/l
1.99
468
2889
787
5556
1.85
30.21
5.7
4.0
33.97
56.52
ng/l
1.48
616
4247
493
2999
1.94
30.15
3.2
2.6
4.68
5.31
e6/l
0.61
450
2695
750
5244
1.83
29.44
2.3
2.2
—
—
—
0
0
41
54
7.77
29.40
1.1
1.1
—
—
—
0
0
89
240
3.87
29.11
1.0
1.0
—
—
—
0
0
71
163
4.52
28.74
1.6
1.5
53.52
65.68
%
1.39
44
105
265
1305
2.24
28.48
2.4
2.5
70.53
69.37
e9/l
0.17
203
1017
60
121
5.12
28.34
1.2
1.1
—
—
—
0
0
690
4760
1.81
27.82
3.3
3.0
1528.03
1581.27
ng/l
0.12
616
4118
89
248
3.75
27.78
1.6
1.6
—
—
—
0
0
170
696
2.62
27.48
1.5
1.7
2.08
1.56
g/l
5.85
138
593
542
3500
1.84
26.94
6.8
4.4
0.00
0.00
estimate
0.50
234
1108
92
273
3.52
26.15
1.2
1.2
3.78
3.90
mmol/l
0.62
83
260
247
1222
2.21
26.10
2.2
2.0
244.88
142.68
ug/g
1.45
200
955
1420
12483
2.63
25.85
35.5
16.1
24.98
26.18
mg/l
0.75
1340
10090
467
2909
1.87
25.84
3.6
2.9
511.09
536.76
mosm/kgh2o
2.00
401
2485
110
368
3.14
25.80
1.4
1.4
—
—
—
0
0
32
37
8.81
25.46
1.1
1.0
—
—
—
0
0
82
232
3.68
25.03
1.2
1.2
—
—
—
0
0
97
307
3.30
24.92
1.2
1.3
456.67
529.85
mg/l
1.11
90
290
131
495
2.80
24.72
2.1
2.3
293.23
1041.11
ug/l
1.08
117
468
441
2731
1.86
24.67
2.0
1.6
1.35
1.46
mg/l
0.27
351
2136
482
3114
1.79
23.23
5.8
4.0
—
—
—
0
0
63
156
4.17
23.15
1.1
1.1
—
—
—
0
0
104
359
3.03
23.10
1.2
1.4
—
—
—
0
0
681
4879
1.71
22.58
3.8
3.5
—
—
—
0
0
78
230
3.52
22.38
1.2
1.2
—
—
—
0
0
320
1848
1.92
21.90
1.3
1.2
—
—
—
0
0
72
209
3.56
21.16
1.5
1.5
—
—
—
0
0
391
2439
1.81
20.84
3.4
2.8
1.73
1.23
e6/l
0.25
252
1406
467
3071
1.74
20.74
2.0
1.8
1108.30
1176.77
nmol/l
0.88
349
2248
357
2170
1.84
20.70
2.3
2.0
29.45
29.82
s
0.43
348
2094
809
6155
1.66
20.70
2.3
2.1
91.04
93.85
pmol/l
0.99
441
3050
76
235
3.35
20.27
4.1
3.0
63.24
59.43
%
1.62
76
235
680
4978
1.65
20.02
3.1
3.5
2.34
2.36
mmol/l
2.04
580
4281
139
601
2.44
19.90
2.2
2.0
—
—
—
0
0
48
109
4.51
19.72
1.1
1.2
—
—
—
0
0
43
90
4.89
19.48
1.5
1.9
—
—
—
0
0
72
224
3.32
19.02
3.9
2.8
5.05
4.52
e9/l
1.00
72
224
1142
9641
1.70
18.27
4.7
4.1
15.40
15.08
pmol/l
3.94
1039
8543
223
1217
1.97
17.76
4.6
3.7
1.22
1.23
mmol/l
0.68
208
1041
258
1486
1.88
17.48
2.1
1.8
—
—
—
0
0
356
2262
1.74
17.41
2.6
3.0
0.81
0.81
mmol/l
0.02
326
2098
53
147
3.70
16.69
2.9
3.4
57.10
57.05
%
0.01
48
125
257
1501
1.85
16.61
5.7
4.5
—
—
—
0
0
87
328
2.75
16.47
1.7
1.7
10349.57
16319.41
e6/l
1.08
70
244
35
71
5.02
16.45
1.1
1.1
—
—
—
0
0
78
281
2.87
16.07
1.3
1.1
74.00
83.53
titre
—
10
17
56
167
3.44
15.84
1.2
1.1
266.90
300.83
u/ml
0.30
30
90
509
3647
1.59
15.29
1.7
1.6
19.10
20.46
nmol/l
1.41
441
3023
56
171
3.36
15.27
2.9
4.2
—
—
—
0
0
350
2285
1.69
15.27
3.7
2.9
4.10
2.52
e6/l
1.23
210
1258
301
1887
1.74
15.23
6.0
4.9
1.06
1.03
mmol/l
0.90
282
1719
464
3275
1.59
14.75
5.7
3.8
—
—
—
0
0
45
123
3.74
14.49
1.0
1.3
—
—
—
0
0
236
1398
1.81
14.45
3.2
2.6
5.62
6.58
ug/l
0.47
199
1213
308
1985
1.69
13.98
2.1
2.0
—
—
—
0
0
476
3417
1.57
13.92
4.5
3.9
89.69
86.64
%
1.85
465
3332
44
122
3.68
13.89
1.4
1.5
32.52
29.43
%
0.20
25
76
208
1199
1.85
13.88
3.5
3.5
92.69
92.91
ng/l
0.01
185
1005
242
1471
1.76
13.53
1.6
1.4
—
—
—
0
0
409
2855
1.59
13.42
6.0
3.9
169.82
323.17
ng/l
1.23
350
2433
24
21
11.59
13.31
1.1
1.0
—
—
—
0
0
24
21
11.59
13.31
1.1
1.0
—
—
—
0
0
24
21
11.59
13.31
1.1
1.0
—
—
—
0
0
70
268
2.69
12.90
1.2
1.3
1915.84
896.03
e6/l
0.25
56
220
70
268
2.69
12.90
1.2
1.2
22.56
40.30
e6/l
0.30
52
211
1395
12809
1.89
12.74
26.7
15.7
—
—
—
0
0
210
1252
1.78
12.50
6.2
6.4
1.41
1.37
mmol/l
0.22
199
1229
24
24
10.14
12.49
1.0
1.0
—
—
—
0
0
123
615
2.09
12.39
1.3
1.2
195.10
206.32
u/ml
0.06
114
553
150
806
1.95
12.37
3.5
3.1
5.08
5.51
e9/l
0.19
101
607
210
1259
1.77
12.25
7.1
6.2
10.64
10.65
mmol/l
0.01
201
1191
416
2970
1.55
12.19
2.8
3.1
2.47
2.47
mmol/l
0.52
359
2603
28
61
4.66
12.14
1.3
1.3
7.14
1.90
%
—
7
10
1318
11946
1.69
12.06
7.5
6.4
41.29
40.75
mmol/mol
1.37
1230
10817
24
46
5.28
12.03
1.1
1.1
86.00
612.36
ng/l
—
6
11
1292
11655
1.65
11.99
5.9
5.0
1.87
2.13
mu/l
1.69
1180
10403
885
7398
1.46
11.61
3.8
3.1
54.36
53.28
u/l
0.14
825
6691
221
1367
1.72
11.53
4.1
3.4
1.95
1.98
mmol/l
0.04
196
1128
53
189
2.87
11.19
1.1
1.3
—
—
—
0
0
343
2397
1.55
10.91
1.3
1.2
1.46
1.45
u/ml
0.01
79
602
48
166
2.95
10.71
1.1
1.1
—
—
—
0
0
1424
13279
1.88
10.69
30.2
19.5
139.37
139.60
mmol/l
2.53
1403
12914
219
1379
1.68
10.66
4.0
3.4
5.75
5.80
kpa
0.34
211
1339
23
48
4.85
10.50
1.0
1.0
—
—
—
0
0
192
1175
1.72
10.37
7.3
7.7
—
—
—
0
0
141
788
1.87
10.32
2.6
2.5
—
—
—
0
0
1181
10556
1.50
10.16
34.5
19.3
15.44
15.42
%
0.04
1163
10349
47
166
2.89
10.12
1.1
1.1
—
—
—
0
0
1423
13301
1.85
10.10
30.7
19.7
3.97
3.99
mmol/l
2.59
1398
12918
200
1247
1.69
10.08
2.6
2.3
29.19
36.81
u/l
2.31
164
1045
46
162
2.90
9.96
1.1
1.3
110.11
104.43
u/ml
—
8
25
195
1215
1.69
9.85
5.4
3.6
—
—
—
0
0
502
3873
1.44
9.61
3.0
3.1
30.17
33.91
u/l
1.75
472
3658
1416
13248
1.79
9.57
20.9
11.1
23.28
24.32
u/l
2.31
1391
12669
116
631
1.91
9.23
1.3
1.3
—
—
—
0
0
36
116
3.15
9.10
1.4
1.2
—
—
—
0
0
218
1427
1.61
9.06
1.3
1.3
—
—
—
0
0
43
156
2.81
8.85
1.1
1.1
—
—
—
0
0
21
47
4.52
8.84
1.1
1.0
—
—
—
0
0
86
434
2.04
8.50
4.6
3.4
—
—
—
0
0
546
4358
1.39
8.35
5.4
4.2
—
—
—
0
0
248
1709
1.54
8.22
6.6
6.6
5.00
5.09
kpa
0.83
235
1625
248
1709
1.54
8.22
6.6
6.6
12.00
12.17
kpa
0.16
235
1626
21
50
4.24
8.21
1.1
1.1
—
73.43
%
—
0
7
225
1521
1.56
8.12
7.0
7.0
95.29
95.41
%
0.07
216
1460
139
834
1.73
8.04
1.3
1.2
—
—
—
0
0
219
1475
1.56
8.03
2.4
2.6
7.07
8.79
umol/l
0.68
192
1297
35
120
2.96
7.99
1.3
1.3
—
—
—
0
0
41
154
2.71
7.94
1.3
2.3
—
—
—
0
0
742
6259
1.36
7.89
2.9
2.7
—
—
—
0
0
80
405
2.03
7.86
1.5
1.4
271.64
282.85
ug/g
0.17
39
243
102
564
1.87
7.75
4.5
3.9
24.85
25.00
mmol/l
0.23
94
519
11
6
18.45
7.60
1.0
1.0
—
—
—
0
0
245
1716
1.51
7.49
6.6
6.6
1.18
1.15
mmol/l
0.03
197
1355
177
1156
1.60
7.39
3.5
2.8
4.64
4.51
kpa
0.38
169
1121
1435
13617
1.72
7.33
44.7
24.2
38.98
39.18
%
0.66
1345
12555
1435
13619
1.72
7.30
44.9
24.1
264.08
245.67
e9/l
17.71
1414
13201
1435
13620
1.72
7.29
44.7
24.1
91.98
91.68
fl
1.67
1418
13359
1435
13620
1.72
7.29
44.8
24.1
7.81
6.79
e9/l
42.97
1411
13148
1435
13622
1.71
7.26
44.8
24.1
4.31
4.38
e12/l
7.89
1411
13148
1435
13622
1.71
7.26
44.6
24.0
30.22
30.39
pg
3.08
1418
13361
35
127
2.80
7.25
1.3
1.1
4.23
5.40
u/ml
0.25
13
58
1435
13625
1.71
7.21
45.1
24.3
129.11
132.27
g/l
14.87
1419
13367
35
128
2.77
7.15
1.4
1.4
16199.45
145167.82
e6/l
1.02
22
92
1329
12409
1.50
7.06
5.9
5.1
5.93
6.07
mmol/l
3.25
1212
11013
206
1409
1.53
7.03
7.4
7.3
118.89
119.31
g/l
0.12
200
1367
1268
11736
1.44
7.02
4.6
4.2
1.30
1.28
mmol/l
0.53
1135
10372
113
665
1.75
7.01
4.5
3.6
—
—
—
0
0
72
367
2.01
6.97
1.2
1.2
—
—
—
0
0
144
912
1.64
6.82
4.3
3.5
5.08
5.20
kpa
1.00
136
866
17
40
4.29
6.76
1.1
1.1
1.03
1.09
ratio
—
5
12
196
1339
1.53
6.72
2.2
2.0
0.22
0.20
g/l
2.15
176
1245
165
1087
1.58
6.64
5.8
4.3
—
—
—
0
0
1312
12261
1.45
6.52
5.2
4.8
4.56
4.54
mmol/l
0.28
1191
11058
145
934
1.61
6.42
8.0
8.3
0.63
0.67
%
0.51
145
925
199
1381
1.51
6.33
3.3
2.9
235.33
227.10
ng/l
0.09
182
1263
11
10
11.07
6.30
1.1
1.1
—
—
—
0
0
55
264
2.12
6.27
1.5
1.5
—
—
—
0
0
100
588
1.75
6.25
1.3
1.2
—
—
—
0
0
140
902
1.61
6.19
4.4
3.5
7.41
7.40
ph
0.25
18
113
18
36
5.05
6.18
1.1
1.1
1736.61
1834.08
miu/ml
0.12
18
36
1299
12148
1.43
6.14
5.2
4.7
1.55
1.48
mmol/l
4.56
1170
10862
47
215
2.22
6.05
2.9
2.1
—
—
—
0
0
123
773
1.64
6.02
7.7
8.8
24.65
24.41
mmol/l
0.42
117
748
1033
9341
1.32
5.97
4.9
4.2
—
—
—
0
0
100
597
1.72
5.93
2.7
2.7
—
—
—
0
0
86
492
1.79
5.91
2.0
2.9
0.24
0.28
g/l
0.36
36
176
143
941
1.57
5.80
8.1
8.1
1.37
1.33
%
0.18
143
932
52
253
2.09
5.75
4.0
2.6
—
—
—
0
0
21
65
3.26
5.73
2.5
2.0
0.16
0.21
e9/l
0.63
21
57
55
276
2.03
5.61
1.7
1.7
5.09
4.68
iu/l
0.05
12
86
127
820
1.60
5.58
7.2
6.8
24.88
24.93
mmol/l
0.06
127
815
55
277
2.02
5.56
1.1
1.2
—
—
—
0
0
110
689
1.64
5.47
3.2
3.1
4.28
4.37
pmol/l
0.35
89
598
77
437
1.80
5.45
1.8
1.9
21.49
21.92
s
0.20
68
400
52
261
2.03
5.32
1.6
1.8
4.49
4.82
mmol/24h
0.27
47
218
73
411
1.81
5.32
1.8
1.6
—
—
—
0
0
18
53
3.42
5.31
1.7
1.7
—
—
—
0
0
5
0
+∞
5.21
1.0
0.0
—
—
—
0
0
36
158
2.31
5.14
1.9
2.3
0.59
1.32
g/24h
1.60
17
71
146
995
1.52
5.07
4.7
4.4
—
—
—
0
0
361
2883
1.33
5.07
7.1
4.5
1.02
1.02
kg/l
0.15
38
448
1331
12594
1.40
5.05
5.9
5.4
2.58
2.63
mmol/l
0.93
1206
11299
9
9
10.05
5.03
2.2
1.3
—
—
—
0
0
96
597
1.65
4.93
5.6
4.2
—
—
—
0
0
23
84
2.76
4.78
2.5
3.3
—
—
—
0
0
66
374
1.80
4.74
4.1
2.6
—
—
—
0
0
412
3385
1.30
4.66
2.6
2.4
—
—
—
0
0
14
31
4.55
4.56
1.0
1.0
—
—
—
0
0
71
417
1.74
4.53
3.7
3.3
0.83
0.81
nmol/l
0.11
56
322
17
54
3.17
4.49
1.6
1.4
—
—
—
0
0
111
734
1.55
4.45
4.5
3.2
25.40
25.26
mmol/l
0.19
105
712
57
316
1.83
4.41
5.9
4.7
8.46
8.38
kpa
0.12
57
311
42
210
2.03
4.39
4.4
2.6
—
—
—
0
0
519
4417
1.26
4.38
2.8
2.5
—
—
—
0
0
35
165
2.15
4.27
3.2
3.2
—
—
—
0
0
21
79
2.68
4.16
1.1
1.2
—
—
—
0
0
56
315
1.81
4.15
5.9
4.7
2.26
2.77
mmol/l
0.76
42
217
56
316
1.80
4.11
5.9
4.7
4.97
5.11
kpa
0.87
56
311
20
74
2.72
4.09
1.2
1.5
—
—
—
0
0
28
123
2.30
4.05
1.2
1.2
—
—
—
0
0
14
42
3.35
4.04
1.2
1.1
—
—
—
0
0
11
22
5.03
4.00
1.0
1.1
—
—
—
0
0
42
218
1.95
3.99
1.8
1.6
—
—
—
0
0
10
18
5.58
3.97
1.0
1.1
—
—
—
0
0
21
82
2.58
3.89
2.3
2.4
—
—
—
0
0
43
228
1.91
3.85
2.7
2.7
—
—
—
0
0
136
971
1.44
3.79
1.5
1.4
—
—
—
0
0
34
167
2.06
3.77
1.1
1.3
—
—
—
0
0
12
29
4.16
3.70
1.3
1.2
—
183.00
—
0
6
29
137
2.14
3.56
1.2
1.3
477.04
288.76
pmol/l
0.60
24
123
10
21
4.79
3.55
1.4
1.0
—
—
—
0
0
32
158
2.05
3.51
1.3
1.2
—
—
—
0
0
502
4350
1.23
3.44
3.2
3.2
818.30
267.26
mg/l
1.12
316
2709
379
3190
1.25
3.40
1.8
1.7
22222718.28
19345206.15
pmol/l
0.04
306
2564
16
59
2.73
3.32
7.5
4.1
—
—
—
0
0
110
775
1.45
3.31
9.8
9.2
—
—
—
0
0
31
155
2.02
3.31
1.3
1.2
—
—
nmol/l
—
0
0
507
4413
1.22
3.30
3.2
3.1
6.88
6.86
mmol/l
0.03
412
3636
18
71
2.55
3.30
2.1
1.8
13.00
17.21
%
0.82
18
66
74
480
1.57
3.29
1.3
1.2
—
—
—
0
0
62
387
1.63
3.24
6.6
4.3
7.43
7.42
ph
0.65
56
341
93
642
1.48
3.12
1.1
1.2
162.82
127.27
iu/ml
0.33
26
229
10
25
4.02
3.08
1.0
1.2
—
—
—
0
0
6
8
7.52
3.05
1.7
1.4
—
—
—
0
0
72
476
1.54
2.98
1.1
1.1
—
165.50
—
0
12
111
803
1.41
2.93
1.3
1.3
—
—
—
0
0
50
304
1.67
2.92
5.0
3.9
—
—
—
0
0
11
32
3.45
2.90
1.7
1.3
42.80
14.10
%
—
5
21
7
13
5.40
2.87
1.0
1.0
—
10.80
—
0
5
26
129
2.03
2.87
1.2
1.4
—
—
—
0
0
12
38
3.17
2.85
2.1
1.5
—
—
—
0
0
128
954
1.37
2.84
7.3
6.2
24.49
24.49
mmol/l
0.00
122
902
224
1810
1.28
2.82
5.2
4.8
34.21
33.72
%
0.25
171
1161
78
540
1.47
2.62
4.4
3.6
1.28
1.42
mmol/l
1.08
78
530
26
135
1.94
2.56
1.4
1.6
—
—
—
0
0
12
42
2.87
2.55
2.3
2.3
48608.33
39485.83
ug/l
0.74
12
42
23
115
2.02
2.51
1.1
1.1
13.68
2.62
u/ml
—
6
39
9
26
3.48
2.48
1.1
1.6
—
—
—
0
0
7
16
4.39
2.47
1.7
1.4
61.29
43.88
umol/l
—
7
16
12
45
2.68
2.45
4.5
2.4
—
—
—
0
0
17
76
2.25
2.44
1.9
1.7
52.65
37.36
%
2.77
17
76
48
304
1.60
2.43
3.1
2.5
15.43
15.85
%
0.34
23
147
15
64
2.36
2.39
1.9
1.2
1.08
1.07
nmol/l
—
10
49
17
77
2.22
2.38
2.4
1.7
—
—
—
0
0
8
22
3.65
2.36
1.5
1.4
—
—
—
0
0
8
22
3.65
2.36
1.3
1.0
—
—
—
0
0
10
33
3.04
2.35
1.0
1.1
—
17.00
%
—
0
5
514
4599
1.18
2.33
3.9
3.7
14.56
8.15
mg/mmol
1.43
321
2814
7
18
3.90
2.25
1.0
1.0
—
—
—
0
0
133
1037
1.31
2.23
1.6
1.5
—
—
—
0
0
450
3999
1.18
2.20
5.4
5.5
4.65
3.11
ug/l
0.34
394
3518
207
1711
1.24
2.17
1.3
1.3
—
—
—
0
0
396
3486
1.18
2.17
1.7
1.6
1.35
1.32
mmol/l
0.24
324
2869
31
181
1.73
2.16
1.2
1.3
28.01
34.38
iu/l
0.53
26
153
6
14
4.30
2.15
1.7
1.2
—
—
—
0
0
6
14
4.30
2.15
1.7
1.2
—
—
—
0
0
6
14
4.30
2.15
1.7
1.2
—
—
—
0
0
11
42
2.63
2.14
1.1
1.3
—
—
—
0
0
48
316
1.54
2.10
2.0
2.4
—
—
—
0
0
16
75
2.15
2.08
1.4
1.3
31.25
36.41
u/l
—
10
61
66
465
1.44
2.08
4.5
3.8
4.01
3.91
mmol/l
0.90
66
459
29
168
1.74
2.08
2.9
2.6
—
—
—
0
0
39
245
1.61
2.08
2.5
1.8
1.79
1.62
mmol/l
0.54
39
237
5
10
5.01
2.07
1.0
1.2
—
—
—
0
0
5
10
5.01
2.07
1.2
1.1
—
—
—
0
0
7
20
3.51
2.05
9.7
6.6
—
—
—
0
0
46
305
1.52
1.97
2.8
2.8
1.92
1.74
mg/l
0.61
39
274
196
1634
1.23
1.92
2.9
4.0
7.74
21.49
ug/l
1.35
157
1345
9
34
2.66
1.86
1.4
1.8
—
—
—
0
0
11
46
2.40
1.85
2.0
1.7
—
—
—
0
0
25
145
1.74
1.82
1.2
1.2
—
—
—
0
0
44
295
1.51
1.81
1.5
1.3
56.11
61.03
mmol/l
0.53
36
240
16
80
2.01
1.80
1.3
1.4
1681.31
1715.79
ml
0.07
16
75
8
29
2.77
1.79
1.3
2.4
—
—
—
0
0
25
147
1.71
1.74
1.0
1.1
1.55
1.57
g/l
0.07
20
129
82
621
1.34
1.73
5.2
4.5
0.89
0.88
%
0.05
77
584
5
14
3.58
1.61
13.2
11.6
4.62
5.91
mmol/l
—
5
14
5
14
3.58
1.61
1.4
1.5
—
—
—
0
0
20
333
0.60
1.52
5.5
3.9
39.15
27.97
mg/l
0.75
13
214
0
44
0.00
1.51
0.0
1.4
—
14.98
—
0
32
81
627
1.31
1.51
5.2
4.4
1.52
1.55
%
0.12
76
589
16
86
1.87
1.50
2.4
2.5
7.44
7.42
ph
—
10
28
11
52
2.12
1.44
1.8
1.2
—
—
—
0
0
18
103
1.76
1.41
1.3
1.1
—
—
—
0
0
8
164
0.49
1.35
1.0
1.1
—
—
—
0
0
32
462
0.69
1.31
1.2
1.4
—
—
—
0
0
16
91
1.77
1.29
1.0
1.2
—
—
—
0
0
5
18
2.78
1.28
1.8
1.1
88.02
180.77
ng/l
—
5
12
26
170
1.54
1.26
1.5
1.5
—
—
—
0
0
9
45
2.01
1.23
1.9
2.4
—
—
—
0
0
59
453
1.31
1.21
6.1
5.6
1.24
1.33
mmol/l
0.49
49
395
97
794
1.24
1.20
4.4
3.9
—
—
—
0
0
13
71
1.84
1.19
1.9
1.7
9.28
10.21
mmol/l
0.39
13
71
12
64
1.88
1.18
1.1
1.5
0.81
1.02
g/l
1.64
12
64
26
381
0.68
1.17
1.3
1.4
—
—
—
0
0
148
1270
1.18
1.14
1.3
1.4
—
—
—
0
0
8
40
2.01
1.12
15.8
28.8
86.38
117.91
ug/l
—
8
34
45
338
1.34
1.09
1.2
1.1
—
—
—
0
0
24
161
1.50
1.07
1.1
1.3
12.35
10.45
u/l
0.29
17
121
40
296
1.36
1.06
1.3
2.7
24.26
35.60
umol/l
5.37
34
257
82
670
1.24
1.05
1.9
2.2
13.29
12.16
nmol/l
0.56
69
577
7
33
2.13
1.05
1.9
2.2
24.57
27.29
%
—
7
28
343
3142
1.12
1.05
1.3
1.3
—
—
—
0
0
9
47
1.92
1.02
1.6
1.1
—
—
—
0
0
7
35
2.00
1.00
1.1
1.8
71.00
85.83
nmol/24h
—
7
35
47
368
1.29
0.89
3.4
3.0
24.39
25.47
mmol/l
1.09
47
358
42
325
1.30
0.87
7.0
6.2
103.92
105.36
mmol/l
1.12
37
291
42
325
1.30
0.87
7.0
6.2
11.19
11.15
mmol/l
0.03
37
291
6
30
2.00
0.87
1.0
1.3
—
—
—
0
0
25
180
1.40
0.82
1.6
1.6
—
—
—
0
0
11
66
1.67
0.78
1.1
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
0.29
—
0
9
0
27
0.00
0.77
0.0
1.0
—
0.36
—
0
5
35
271
1.30
0.74
3.0
2.8
—
—
—
0
0
251
2308
1.10
0.74
3.5
3.3
0.64
0.78
ug/l
3.43
188
1622
68
571
1.20
0.73
2.6
3.3
68.45
2647.29
u/ml
0.86
55
496
22
299
0.73
0.72
2.1
1.6
—
—
—
0
0
7
42
1.67
0.68
1.9
2.1
—
—
—
0
0
5
91
0.55
0.67
1.2
1.2
—
—
—
0
0
12
78
1.54
0.65
1.9
1.2
—
—
—
0
0
7
44
1.59
0.65
1.0
1.4
150.43
155.22
mmol/24h
—
7
44
0
21
0.00
0.60
0.0
2.4
—
—
—
0
0
38
308
1.24
0.60
2.4
2.2
127.72
127.59
g/l
0.02
29
227
21
276
0.76
0.58
3.1
3.6
30.19
43.55
u/ml
0.68
21
268
12
81
1.49
0.57
1.4
1.8
—
—
—
0
0
338
3575
0.93
0.56
3.2
3.2
—
—
—
0
0
21
159
1.33
0.55
1.1
1.2
287.07
233.24
miu/ml
—
6
57
104
932
1.12
0.52
3.9
3.5
—
—
—
0
0
39
324
1.21
0.51
3.1
2.8
7.87
7.84
kpa
0.05
39
312
13
92
1.42
0.50
3.8
3.1
—
—
—
0
0
7
47
1.49
0.47
1.0
1.4
1.45
1.57
g/l
—
7
47
16
120
1.34
0.46
3.3
3.1
77.68
30.74
mg/l
0.38
11
95
17
130
1.31
0.44
1.5
2.2
0.63
1.92
u/field
—
8
37
5
33
1.52
0.41
31.0
24.5
6.54
6.53
ug/l
—
5
27
41
352
1.17
0.40
2.0
2.3
274.93
72.54
ug/min
0.49
20
204
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
23
187
1.23
0.39
1.3
1.4
5160.67
91471.50
e6/l
1.64
15
113
12
89
1.35
0.38
3.5
2.3
—
—
—
0
0
21
170
1.24
0.37
1.1
1.3
—
—
—
0
0
5
37
1.35
0.37
1.6
1.4
—
—
—
0
0
9
70
1.29
0.36
1.1
1.5
—
—
—
0
0
12
91
1.32
0.33
1.4
1.1
—
—
—
0
0
12
92
1.31
0.32
1.4
1.1
—
—
—
0
0
7
54
1.30
0.30
1.0
1.3
—
—
—
0
0
20
166
1.21
0.30
1.4
1.5
—
—
—
0
0
21
177
1.19
0.27
1.1
1.1
3.80
115.13
iu/ml
—
5
34
5
72
0.69
0.26
1.4
1.7
85.20
86.97
umol/l
—
5
72
10
125
0.80
0.23
2.2
1.4
9.83
10.83
%
—
10
125
5
39
1.28
0.23
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
51.67
—
0
6
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
0.04
—
0
7
18
154
1.17
0.21
1.3
1.2
284.69
275.45
mosm/kgh2o
0.84
13
110
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
23
260
0.88
0.19
1.4
1.4
0.81
0.81
nmol/l
0.01
11
212
10
81
1.24
0.18
1.0
1.2
—
—
—
0
0
6
53
1.13
0.18
5.5
3.0
13.83
13.28
%
—
6
53
981
9901
0.97
0.18
40.3
22.0
328.14
331.04
g/l
19.84
973
9816
24
215
1.12
0.16
2.6
2.6
—
—
—
0
0
8
70
1.14
0.16
3.3
6.0
—
—
—
0
0
29
316
0.92
0.14
1.1
1.1
—
—
—
0
0
40
427
0.94
0.13
27.3
11.8
—
—
—
0
0
115
1187
0.97
0.11
1.4
1.5
—
—
—
0
0
11
96
1.15
0.10
1.4
1.3
—
—
—
0
0
28
261
1.07
0.10
1.1
1.2
—
—
—
0
0
5
45
1.11
0.09
7.2
1.7
12.66
18.32
ug/l
—
5
38
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
5
63
0.79
0.08
1.8
1.2
79.00
402.40
u/l
—
5
57
10
89
1.12
0.07
2.1
1.6
—
—
—
0
0
9
104
0.86
0.06
1.0
1.2
—
—
—
0
0
16
148
1.08
0.06
2.0
2.1
—
—
—
0
0
12
128
0.94
0.02
1.1
1.0
—
—
—
0
0
13
136
0.96
0.00
1.3
1.1
—
—
—
0
0
10
104
0.96
0.00
1.0
1.2
—
—
—
0
0
10
104
0.96
0.00
1.6
2.5
7.04
7.25
mmol/l
—
10
64
10
104
0.96
0.00
1.0
1.2
—
—
—
0
0
16
158
1.01
0.00
2.7
4.5
270.50
355.01
umol/l
—
10
136
36
358
1.01
0.00
1.5
1.3
—
—
—
0
0
44
438
1.00
0.00
5.4
5.0
—
—
—
0
0
10
103
0.97
0.00
1.0
1.2
—
—
—
0
0
16
155
1.03
0.00
1.5
1.7
—
—
—
0
0
7
79
0.89
0.00
18.4
13.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
85
0.94
-0.00
1.0
1.1
—
—
—
0
0
9
98
0.92
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.9
—
—
—
0
0
8
84
0.95
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
33.00
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
335.17
—
0
6

Mortality – FinRegistry

Association

Association between endpoint M13_GIANTCELL and mortality.

Females

Parameter HR [95% CI] p-value
M13_GIANTCELL 1.291 [1.17, 1.42] < 0.001
Birth year 0.992 [0.98, 1.0] 0.054

During the follow-up period (1.1.1998 — 31.12.2019), 1604 out of 4624 females with M13_GIANTCELL died.

Males

Parameter HR [95% CI] p-value
M13_GIANTCELL 1.32 [1.14, 1.52] < 0.001
Birth year 0.986 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 859 out of 2239 males with M13_GIANTCELL died.

Mortality risk

Mortality risk for people of age

years, who have M13_GIANTCELL.

N-year risk Females Males
1 0.134% 0.217%
5 0.717% 1.508%
10 1.759% 3.57%
15 3.324% 7.161%
20 5.818% 12.419%

Relationships between endpoints

Index endpoint: M13_GIANTCELL – Giant cell arteritis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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