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Epiphora

DOID EFO Endpoint Browser PheWeb

H7_EPIPHORA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H04.2
  • Hospital discharge: ICD-9 — 3752
  • Cause of death: ICD-10 — H04.2
  • Cause of death: ICD-9 — 3752

2 out of 7 registries used, show all original rules.

824

4. Check minimum number of events

None

824

5. Include endpoints

None

824

6. Filter based on genotype QC (FinnGen only)

793

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H04
Name in latin
Epiphora

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5034 3324 1700
Only index persons 4691 3161 1530
Unadjusted period prevalence (%)
Whole population 0.08 0.10 0.05
Only index persons 0.10 0.12 0.06
Median age at first event (years)
Whole population 58.49 57.92 59.66
Only index persons 58.69 58.09 59.95

-FinnGen-

Key figures

All Female Male
Number of individuals 793 565 228
Unadjusted period prevalence (%) 0.17 0.20 0.10
Median age at first event (years) 61.95 60.57 65.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
824
Matched controls
8240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
520.3
307.7
338
11
H04.2
ICD-10 Finland
Epiphora
4503599627370496.0
307.7
817
6
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
3559.6
290.3
263
*
H04.10
ICD-10 Finland
Dry eye syndrome
10.3
164.0
211
266
H02.3
ICD-10 Finland
Blepharochalasis
68.5
156.6
86
14
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
1667.9
147.5
139
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
753.5
133.6
128
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.4
98.3
485
2006
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.2
84.7
549
2664
H02.4
ICD-10 Finland
Ptosis of eyelid
39.6
73.1
45
12
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
750.0
71.2
69
*
S01GX01
ATC
cromoglicic acid; ophthalmic
3.8
67.1
276
958
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
529.2
51.0
50
*
H02.1
ICD-10 Finland
Ectropion of eyelid
177.2
48.4
50
*
H01.0
ICD-10 Finland
Blepharitis
5.7
42.3
84
162
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
37.8
36
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
383.9
37.3
37
*
ZXA10
NOMESCO Finland
Bilateral
2.9
37.2
225
945
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.9
33.0
104
291
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
32.5
31
*
F03
ICPC
Eye discharge
4.2
32.4
93
243
WX002
NOMESCO Finland
Sedation and analgesia
2.6
29.9
217
989
F29
ICPC
Eye symptom/complaint other
3.4
29.7
119
390
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
144.7
26.8
28
*
R01AD09
ATC
mometasone; nasal
2.2
26.6
423
2678
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
26.2
25
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
26.2
25
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.7
25.5
28
27
WX110
NOMESCO Finland
Infiltration anesthesia
2.3
24.6
619
4640
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.5
22.6
82
251
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
6.5
22.4
37
59
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
36.2
22.2
28
8
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
204.7
19.6
20
*
L17
ICPC
Foot/toe symptom/complaint
2.0
19.4
283
1683
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.6
19.3
67
199
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
18.2
173
870
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
18.0
279
1688
E0000UV, ,
ATC
1.9
17.7
367
2445
S18
ICPC
Laceration/cut
1.9
17.6
407
2808
R01AD58
ATC
fluticasone, combinations; nasal
2.1
17.5
215
1194
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
17.2
394
2703
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
16.9
217
1223
CCD30
NOMESCO Finland
Reconstruction of lacrimal canaliculus
173.4
16.6
17
*
ZXA00
NOMESCO Finland
Right side
2.0
16.3
253
1523
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
16.1
316
2052
A02BC05
ATC
esomeprazole; systemic
1.8
16.1
367
2498
H00.1
ICD-10 Finland
Chalazion
5.5
16.0
31
58
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
15.7
264
1627
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
15.7
15
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
15.2
254
1561
UDM02
NOMESCO Finland
Sinoscopy
4.9
15.1
33
69
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.5
14.9
99
423
J01DB01
ATC
cefalexin; oral
2.1
14.8
687
5778
CBB30
NOMESCO Finland
Excision of lesion of eyelid
4.4
14.7
37
87
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
14.6
14
*
H10.5
ICD-10 Finland
Blepharoconjunctivitis
5.9
14.5
26
45
R13
ICD-10 Finland
Dysphagia
2.8
14.4
74
278
M03BX02
ATC
tizanidine; oral
1.8
14.3
522
4038
S01GX08
ATC
ketotifen; ophthalmic
3.5
14.2
50
150
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.0
14.1
66
235
J02AC01
ATC
fluconazole; systemic
1.8
14.0
352
2439
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
13.9
451
3358
SPAT1153
SPAT
Removal of sutures
1.8
13.9
289
1892
H57.1
ICD-10 Finland
Ocular pain
4.0
13.7
40
105
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
13.6
259
1648
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.3
13.5
109
509
S01GX09
ATC
olopatadine; ophthalmic
4.3
13.3
35
85
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.2
13.3
126
628
L03
ICPC
Low back symptom/complaint
1.8
13.3
248
1568
UJF32
NOMESCO Finland
Coloscopy
1.8
13.1
235
1466
R01AD08
ATC
fluticasone; nasal
1.8
13.0
243
1534
M48.0
ICD-10 Finland
Spinal stenosis
2.1
12.9
132
679
SPAT1260
SPAT
Consultation of another employee
2.0
12.8
165
923
N03AX16
ATC
[U] pregabalin
1.9
12.8
217
1330
ZXE00
NOMESCO Finland
One hour or less
1.7
12.7
328
2275
R01AD12
ATC
fluticasone furoate; nasal
1.8
12.6
256
1657
N02BE01
ATC
paracetamol; systemic, rectal
2.4
12.5
748
6617
CCD40
NOMESCO Finland
Percutaneous dacryocystorhinostomy
+∞
12.5
12
*
ZXA05
NOMESCO Finland
Left side
1.8
12.5
226
1410
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
12.4
531
4213
R06AX27
ATC
desloratadine; oral
1.8
12.2
228
1435
R03DC03
ATC
montelukast; oral
2.0
12.2
152
839
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
12.1
143
775
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
12.0
302
2072
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
11.7
78
333
L01
ICPC
Neck symptom/complaint
2.0
11.7
140
760
R06AE07
ATC
cetirizine; oral
1.7
11.7
361
2611
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
11.5
343
2454
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
11.5
140
765
WX720
NOMESCO Finland
Own respiration
2.9
11.5
54
193
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
11.5
11
*
H02.2
ICD-10 Finland
Lagophthalmos
+∞
11.5
11
*
M19.9
ICD-10 Finland
Arthrosis, unspecified
3.0
11.5
52
182
H10
ICD-10 Finland
Conjunctivitis
2.7
11.5
62
239
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
11.4
222
1412
H10.4
ICD-10 Finland
Chronic conjunctivitis
12.0
11.4
20
17
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.2
11.3
44
141
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
11.2
346
2493
M01AH05
ATC
etoricoxib; oral
1.7
11.2
501
3972
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.1
11.1
117
606
J01AA02
ATC
doxycycline; systemic
1.8
11.1
645
5481
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
11.0
417
3163
M79.6
ICD-10 Finland
Pain in limb
1.7
10.9
357
2607
J01CA04
ATC
amoxicillin; systemic
1.8
10.9
660
5657
H02AB06
ATC
prednisolone; systemic
1.6
10.8
390
2918
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
10.8
384
2862
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
10.7
65
266
H04.0
ICD-10 Finland
Dacryoadenitis
60.8
10.6
12
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
10.6
219
1412
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.4
10.6
76
336
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
10.5
82
377
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
+∞
10.4
10
*
CCC99
NOMESCO Finland
Other operation on lacrimal passages
+∞
10.4
10
*
AA1AD
NOMESCO Finland
CT of head and brain
1.7
10.3
232
1531
H02AB07
ATC
prednisone; oral
2.0
10.2
128
705
L08
ICPC
Shoulder symptom/complaint
1.8
10.2
190
1187
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
14.8
10.0
16
11
N02AX02
ATC
tramadol; systemic, rectal
1.6
10.0
353
2611
S01XA18
ATC
ciclosporin; ophthalmic
40.6
10.0
12
*
SPAT1301
SPAT
No procedures
1.7
9.9
269
1864
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.2
9.9
39
126
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.8
229
1523
R03AC02
ATC
salbutamol; inhalant
1.6
9.8
448
3518
A02BC01
ATC
omeprazole; systemic
1.7
9.8
233
1557
F01
ICPC
Eye pain
3.6
9.7
32
92
J31.0
ICD-10 Finland
Chronic rhinitis
2.3
9.7
75
343
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
9.6
562
4672
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
9.6
167
1022
Z01.2
ICD-10 Finland
Dental examination
1.6
9.5
355
2652
G44.2
ICD-10 Finland
Tension-type headache
2.0
9.5
119
655
R21
ICPC
Throat symptom/complaint
1.8
9.4
159
964
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
9.4
9
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
9.4
9
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.7
9.3
29
80
D07AC01
ATC
betamethasone; topical
1.6
9.3
287
2046
S21
ICPC
Skin texture symptom/complaint
1.9
9.3
125
705
A02BC03
ATC
lansoprazole; oral
1.6
9.2
249
1716
M54.5
ICD-10 Finland
Low back pain
1.6
9.2
289
2067
R03BA08
ATC
ciclesonide; inhalant
2.2
9.2
79
378
S01AX11
ATC
[U] ofloxacin
3.2
9.1
35
111
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.1
9.0
38
128
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
9.0
99
521
A02BA02
ATC
ranitidine; systemic
1.7
8.9
170
1066
G04BD12
ATC
mirabegron; oral
1.9
8.9
111
610
E000001, ,
ATC
1.8
8.8
162
1007
R05
ICD-10 Finland
Cough
1.7
8.7
179
1145
S29
ICPC
Skin symptom/complaint other
1.8
8.7
157
968
SFA20
NOMESCO Finland
Two-surface restoration
1.6
8.7
450
3597
M54.6
ICD-10 Finland
Pain in thoracic spine
2.3
8.6
65
294
J01EA01
ATC
trimethoprim; systemic
1.6
8.6
234
1612
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
8.6
186
1208
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
8.6
306
2249
KMAK, ,
NOMESCO Finland
1.5
8.5
388
3010
F16
ICPC
Eyelid symptom/complaint
2.7
8.5
44
166
H26.4
ICD-10 Finland
After-cataract
2.0
8.5
92
481
R06AX26
ATC
fexofenadine; oral
2.3
8.5
62
277
A02BC02
ATC
pantoprazole; systemic
1.6
8.4
551
4628
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
8.4
178
1149
L84
ICPC
Back syndrome without radiat pain
2.6
8.4
49
197
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
8.4
247
1734
CBF99
NOMESCO Finland
Other operation for ectropion
+∞
8.3
8
*
CBN50
NOMESCO Finland
Excision of tarsus and skin
+∞
8.3
8
*
J01FA10
ATC
azithromycin; systemic
1.5
8.3
449
3610
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
8.3
90
471
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
8.3
305
2254
R42
ICD-10 Finland
Dizziness and giddiness
1.7
8.2
193
1278
N03AX12
ATC
[U] gabapentin; oral
1.8
8.2
144
880
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.1
525
4376
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
8.1
120
696
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
8.1
93
496
ZXD20
NOMESCO Finland
Day surgery
1.9
8.1
112
637
WX704
NOMESCO Finland
Intubation
2.2
8.1
70
336
A97
ICPC
No disease
1.7
8.0
152
949
N05CF01
ATC
zopiclone; oral
1.6
8.0
271
1959
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.0
145
894
F13
ICPC
Eye sensation abnormal
3.3
8.0
29
89
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.3
8.0
60
271
WX402
NOMESCO Finland
General anaesthesia
1.7
8.0
163
1040
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
7.9
71
345
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
7.9
92
493
M79.1
ICD-10 Finland
Myalgia
1.8
7.9
120
703
R07.0
ICD-10 Finland
Pain in throat
2.4
7.8
53
229
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
7.8
102
570
R05
ICPC
Cough
1.6
7.8
200
1355
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.7
7.7
158
1008
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.8
7.7
39
146
M02AA07
ATC
piroxicam; topical
1.5
7.7
299
2229
N39.3
ICD-10 Finland
Stress incontinence
2.1
7.6
75
378
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
6.8
7.6
18
27
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
7.6
91
493
CBB00
NOMESCO Finland
Excision of chalazion
25.3
7.6
10
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
7.6
223
1559
J46
ICD-10 Finland
Status asthmaticus
3.4
7.6
27
82
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.1
7.5
30
98
R51.80
ICD-10 Finland
Headache
1.8
7.5
123
737
R09.1
ICD-10 Finland
Pleurisy
4.0
7.5
21
54
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.5
176
1165
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
4.5
7.5
18
41
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.5
7.3
429
3470
H02AB04
ATC
methylprednisolone; systemic
1.8
7.3
118
703
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
7.3
244
1754
3752A
ICD-9 Finland
Disorders of lachrymal system, Epiphora
+∞
7.3
7
*
G03DC05
ATC
[U] tibolone
2.3
7.3
52
230
SFA10
NOMESCO Finland
One-surface restoration
1.5
7.3
418
3367
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
7.2
150
959
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
7.2
143
903
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.2
302
2280
N03AE01
ATC
clonazepam; systemic
2.4
7.2
51
225
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
7.2
234
1672
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
7.2
118
707
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.7
7.1
37
140
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
7.1
158
1028
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.6
7.1
185
1253
R53
ICD-10 Finland
Malaise and fatigue
1.6
7.1
191
1304
H29
ICPC
Ear symptom/complaint other
1.9
7.1
95
534
SPAT1053
SPAT
Memory test
1.8
7.1
120
726
J01FA06
ATC
roxithromycin; oral
1.5
7.1
318
2434
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
7.0
87
476
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.6
7.0
212
1487
R03BA02
ATC
budesonide; inhalant
1.7
7.0
148
951
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.8
7.0
33
119
TPH07
NOMESCO Finland
Cathetrisation of artery
1.9
6.9
92
516
N06AX11
ATC
mirtazapine; oral
1.5
6.9
274
2041
XCK10
NOMESCO Finland
Photography of fundus of eye
2.0
6.9
77
407
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.0
6.9
74
386
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
6.9
41
167
L13
ICPC
Hip symptom/complaint
1.6
6.9
162
1071
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.9
165
1096
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
6.8
122
749
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
6.8
272
2029
R03BB04
ATC
tiotropium bromide; inhalant
1.9
6.8
83
453
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
6.7
84
461
M25.5
ICD-10 Finland
Pain in joint
1.5
6.7
251
1844
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
6.7
57
272
R50.9
ICD-10 Finland
Fever, unspecified
1.8
6.7
113
683
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
6.6
180
1230
SPAT1263
SPAT
Sampling
1.5
6.6
335
2616
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
6.6
50
227
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.6
153
1007
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
6.5
341
2676
R03AC03
ATC
terbutaline; inhalant
1.8
6.5
110
663
N05CF02
ATC
zolpidem; oral
1.7
6.5
143
928
D09
ICPC
Nausea
2.5
6.5
41
172
A03FA02
ATC
cisapride; oral, rectal
2.0
6.5
66
338
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.3
6.4
49
223
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.4
318
2468
R06AX13
ATC
loratadine; oral
1.7
6.4
120
745
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
6.4
331
2592
L16
ICPC
Ankle symptom/complaint
1.8
6.3
95
555
N17
ICPC
Vertigo/dizziness
1.8
6.3
106
640
CC1CB
NOMESCO Finland
Dacryocystography
+∞
6.3
6
*
CBN40
NOMESCO Finland
Excision of tarsus
+∞
6.3
6
*
R03AC13
ATC
formoterol; inhalant
2.3
6.3
47
213
H02.8
ICD-10 Finland
Other specified disorders of eyelid
26.9
6.2
8
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.1
6.2
57
280
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
6.2
74
400
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.2
126
800
R04.0
ICD-10 Finland
Epistaxis
2.0
6.2
64
329
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
6.2
45
201
M67.4
ICD-10 Finland
Ganglion
2.1
6.2
56
274
L14
ICPC
Leg/thigh symptom/complaint
2.0
6.2
70
372
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
6.2
108
658
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.2
116
721
Z2221
NOMESCO Finland
Medical doctor
1.5
6.2
209
1499
C10AA07
ATC
rosuvastatin; oral
1.5
6.2
249
1853
XQ800
NOMESCO Finland
Prick test
2.1
6.2
57
281
J01FF01
ATC
clindamycin; systemic
1.5
6.2
208
1491
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.9
6.2
28
99
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
6.1
328
2578
U05
ICPC
Urination problems other
2.3
6.1
46
209
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
6.1
84
477
J01DA09
ATC
[U] cefadroxil
1.5
6.1
202
1443
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.1
193
1366
SDA03
NOMESCO Finland
Periodontal treatment
1.5
6.0
291
2241
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.0
491
4167
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
6.0
229
1683
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
6.0
29
106
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
6.0
58
291
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
6.0
179
1248

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
163
732
2.53
22.54
1.9
1.6
—
—
—
0
0
594
4757
1.89
14.74
5.9
4.4
—
—
—
0
0
629
5141
1.94
14.54
5.3
4.1
13.21
12.87
mm/h
0.23
598
4718
402
2880
1.77
14.35
2.2
2.0
101.98
95.65
pmol/l
1.67
189
1458
204
1191
1.95
14.08
1.3
1.3
24.42
33.56
iu/ml
0.61
71
393
158
856
2.05
13.43
1.4
1.3
271.11
531.46
titre
2.93
36
192
464
3525
1.72
12.94
7.8
5.6
0.19
0.19
e9/l
0.06
413
3096
461
3497
1.72
12.92
7.5
5.3
1.86
1.94
e9/l
0.53
412
3098
451
3408
1.71
12.75
7.5
5.3
0.04
0.04
e9/l
0.75
397
2951
427
3182
1.71
12.69
7.7
5.5
2.83
2.79
%
0.11
403
2960
429
3201
1.71
12.69
8.1
5.8
9.05
8.53
%
2.21
406
2981
432
3231
1.71
12.65
7.6
5.3
56.71
57.38
%
0.61
407
3014
449
3398
1.71
12.55
7.5
5.3
0.59
0.57
e9/l
0.77
395
2943
733
6438
2.25
12.36
6.0
4.9
2.00
2.12
mu/l
0.25
677
5847
761
6805
2.55
12.06
18.4
13.9
19.61
23.36
mg/l
2.89
626
5368
412
3078
1.68
11.83
7.9
5.5
0.73
0.68
%
1.04
387
2853
433
3278
1.68
11.81
7.9
5.6
28.72
27.79
%
1.03
410
3062
503
3984
1.67
11.32
10.5
8.8
3.88
4.05
e9/l
1.14
447
3499
422
3206
1.65
11.09
7.9
5.8
—
—
—
0
0
398
2988
1.64
10.90
4.6
4.5
35.58
35.29
g/l
0.49
363
2775
637
5427
1.77
10.44
4.9
4.1
14.94
14.88
pmol/l
0.27
582
4894
632
5379
1.75
10.31
9.2
7.4
75.97
78.52
u/l
1.06
605
5025
185
1145
1.79
10.29
1.3
1.3
12.08
13.56
u/ml
0.09
65
431
391
2958
1.61
10.13
3.1
2.7
128.43
118.49
ug/l
0.40
361
2698
416
3220
1.59
9.62
5.9
5.6
1.21
1.22
mmol/l
0.40
386
2914
81
390
2.19
9.26
1.2
1.2
228.50
223.33
u/ml
0.02
71
354
426
3356
1.56
8.85
4.1
3.8
0.04
0.00
estimate
0.47
77
711
197
1290
1.69
8.84
4.5
3.8
64.89
322.30
ng/l
3.99
158
1021
290
2093
1.59
8.83
2.7
2.1
206.85
202.60
u/l
0.03
275
1978
441
3512
1.55
8.65
6.8
6.4
1.22
1.22
mmol/l
0.17
383
2976
134
791
1.83
8.61
1.7
1.4
—
—
—
0
0
296
2159
1.58
8.56
2.8
2.4
58.40
58.75
u/l
0.03
268
1986
771
7107
2.32
8.40
17.3
13.5
—
—
—
0
0
428
3405
1.53
8.30
4.0
3.8
0.00
0.01
estimate
0.80
71
642
424
3372
1.53
8.20
5.6
5.1
0.00
0.00
estimate
0.50
73
656
453
3660
1.53
8.09
6.9
6.1
10.37
10.81
umol/l
0.45
426
3469
157
988
1.73
8.09
1.3
1.2
—
—
—
0
0
573
4879
1.57
8.01
4.5
3.8
—
—
—
0
0
363
2803
1.53
7.98
2.3
2.1
—
—
—
0
0
287
2109
1.55
7.90
4.7
3.9
7.40
7.40
ph
0.01
51
399
217
1495
1.61
7.87
1.3
1.2
0.80
1.76
u/ml
1.60
51
386
487
4010
1.52
7.86
4.6
4.4
6.57
6.71
mmol/l
1.07
455
3744
54
239
2.35
7.54
1.2
1.2
0.19
1.52
u/ml
—
7
19
343
2649
1.51
7.37
3.7
3.5
5.60
5.84
ph
0.74
21
165
374
2946
1.49
7.26
2.4
2.3
80.79
78.44
nmol/l
0.77
328
2607
220
1550
1.57
7.18
3.3
3.7
—
—
—
0
0
735
6728
1.86
7.10
5.5
4.7
5.88
5.95
mmol/l
0.86
668
6053
95
538
1.87
6.93
1.3
1.2
—
—
—
0
0
147
946
1.67
6.91
2.2
1.9
—
—
—
0
0
237
1715
1.54
6.81
1.6
1.5
23.84
21.09
nmol/l
1.22
203
1422
105
626
1.78
6.48
1.9
2.0
383.57
380.56
nmol/l
0.06
100
573
746
6903
1.85
6.35
5.7
5.0
2.74
2.75
mmol/l
0.03
686
6291
763
7113
1.98
6.32
20.7
16.3
139.64
139.69
mmol/l
0.21
751
6917
508
4321
1.46
6.28
3.8
3.0
50.67
47.90
u/l
0.32
463
3979
797
7560
2.66
6.26
27.8
20.9
6.57
6.70
e9/l
0.97
782
7338
125
791
1.68
6.24
1.9
2.1
127.68
126.26
ug/g
0.02
90
619
764
7131
1.98
6.22
20.9
16.4
3.95
3.97
mmol/l
0.69
751
6922
245
1817
1.50
6.18
4.9
4.0
—
—
—
0
0
796
7557
2.57
6.04
27.8
20.9
39.66
39.64
%
0.04
718
7037
396
3233
1.43
6.00
16.2
14.5
1.24
1.24
inr
0.01
105
927
796
7560
2.56
5.98
27.7
20.8
91.43
91.17
fl
0.98
787
7441
796
7561
2.55
5.96
27.7
20.8
30.39
30.26
pg
1.32
787
7441
796
7562
2.55
5.94
27.8
20.9
4.39
4.43
e12/l
1.57
779
7341
796
7564
2.54
5.90
28.0
21.0
132.65
133.35
g/l
0.78
787
7442
698
6372
1.62
5.87
6.3
5.8
39.31
39.93
mmol/mol
1.20
643
5864
70
379
1.93
5.86
2.7
2.4
—
—
—
0
0
139
918
1.62
5.86
2.1
2.4
21.90
21.64
%
0.07
117
781
23
75
3.13
5.80
1.0
1.0
0.73
2.43
u/ml
—
10
26
795
7559
2.47
5.72
27.9
20.9
248.98
253.16
e9/l
1.11
780
7360
118
754
1.66
5.66
2.9
2.7
8.85
7.97
umol/l
0.14
103
643
730
6757
1.70
5.60
5.0
4.5
4.68
4.69
mmol/l
0.17
676
6203
55
278
2.05
5.60
2.8
1.6
10.57
10.90
u/ml
—
6
6
774
7293
2.01
5.56
13.9
10.4
25.63
24.52
u/l
1.13
755
7004
656
5927
1.52
5.53
21.9
16.8
14.95
15.07
%
0.20
642
5823
23
79
2.97
5.34
1.0
1.0
6.21
4.33
u/ml
0.15
11
34
144
981
1.57
5.31
2.1
2.4
2.36
2.36
g/l
0.00
133
899
189
1367
1.50
5.29
1.7
1.7
1095.00
1209.06
nmol/l
0.99
137
1005
228
1723
1.45
5.08
2.9
2.6
1464.47
6628.46
umol/l
2.74
195
1497
153
1068
1.53
5.05
2.1
2.4
12.74
12.62
umol/l
0.07
144
983
222
1675
1.45
4.98
4.4
3.6
91.08
91.00
%
0.01
217
1629
24
88
2.78
4.98
1.1
1.1
0.74
2.63
u/ml
—
8
45
178
1287
1.49
4.96
1.5
1.5
2.35
2.45
g/l
0.37
107
757
295
2347
1.40
4.90
3.8
3.2
—
—
—
0
0
722
6713
1.61
4.84
5.0
4.4
1.50
1.52
mmol/l
0.44
667
6117
154
1092
1.50
4.71
4.0
3.1
0.83
0.81
mmol/l
0.55
146
1022
275
2174
1.40
4.70
3.7
3.2
34.53
30.86
u/l
0.71
262
2060
229
1757
1.42
4.64
2.5
2.1
2.84
3.12
mg/l
0.99
194
1489
20
69
2.95
4.63
1.1
1.0
0.31
1.80
u/ml
—
7
30
82
503
1.70
4.59
1.6
1.4
—
—
—
0
0
24
93
2.63
4.50
3.9
2.4
—
—
—
0
0
199
1505
1.42
4.34
1.7
1.7
0.88
1.24
mg/l
2.58
158
1164
12
24
5.06
4.33
1.0
1.0
0.31
0.27
u/ml
—
6
7
10
16
6.31
4.30
1.4
1.5
—
—
—
0
0
364
3045
1.35
4.28
12.9
9.1
0.00
0.00
e9/l
0.39
302
2502
28
122
2.34
4.14
1.3
1.6
—
—
—
0
0
17
57
3.02
4.14
1.2
1.3
—
—
—
0
0
300
2450
1.35
4.08
2.9
3.5
2.35
2.36
mmol/l
0.72
251
2119
384
3255
1.34
4.06
2.8
2.5
—
—
—
0
0
69
420
1.70
4.00
2.5
2.5
16.58
22.96
au/ml
—
6
30
320
2651
1.34
3.92
4.0
3.6
22.03
50.81
ng/l
1.49
225
1892
92
609
1.57
3.84
2.8
2.2
52.03
37.49
u/l
0.35
79
512
60
357
1.73
3.78
1.3
1.2
—
—
—
0
0
78
498
1.63
3.78
2.9
2.5
—
—
—
0
0
96
645
1.55
3.76
1.8
2.1
0.20
0.21
g/l
0.73
85
608
46
255
1.85
3.66
2.5
2.4
10.90
10.41
g/l
0.24
41
228
41
219
1.92
3.65
2.7
2.2
38.00
37.65
g/l
0.13
36
193
78
503
1.61
3.64
3.3
2.9
10.28
10.54
g/l
0.19
72
460
39
206
1.94
3.59
1.1
1.1
—
—
—
0
0
693
6483
1.43
3.52
4.4
4.0
1.31
1.27
mmol/l
0.62
634
5857
8
13
6.20
3.50
1.3
1.3
—
—
—
0
0
152
1137
1.41
3.48
2.7
2.6
1.15
1.24
e6/l
0.12
89
636
65
405
1.66
3.48
1.5
1.6
1.22
1.51
g/l
0.85
59
371
71
453
1.62
3.46
1.3
1.2
—
—
—
0
0
87
586
1.54
3.38
2.9
3.6
99.19
85.27
ng/l
0.67
77
515
108
763
1.48
3.35
1.3
1.3
—
—
—
0
0
32
163
2.00
3.28
1.4
1.7
21010.11
15043.29
e6/l
0.13
27
124
20
84
2.42
3.25
1.3
1.5
49.00
59.07
%
—
9
57
212
1692
1.34
3.24
9.7
6.5
—
—
—
0
0
50
297
1.73
3.20
1.6
1.8
—
—
—
0
0
86
586
1.52
3.18
3.2
2.9
66.23
66.87
g/l
0.33
79
527
196
1562
1.33
3.01
1.7
1.7
464.06
29236047.03
pmol/l
1.83
158
1269
105
754
1.45
3.01
5.4
6.9
11.92
12.30
kpa
0.32
99
721
106
763
1.45
3.00
5.3
6.9
1.80
1.28
mmol/l
0.81
85
607
84
581
1.50
2.91
2.5
2.5
64.03
71.04
e9/l
1.30
64
457
49
299
1.68
2.87
1.8
1.8
1.46
1.52
g/l
0.18
44
261
38
221
1.75
2.66
1.4
1.5
278.06
294.51
ug/g
0.19
21
134
246
2056
1.28
2.63
2.8
3.1
1126.68
1365.07
ng/l
0.53
214
1733
18
81
2.25
2.55
1.3
1.2
—
—
—
0
0
133
1027
1.35
2.51
2.0
1.9
30.01
29.45
s
0.60
125
995
66
450
1.51
2.47
4.2
4.3
—
—
—
0
0
34
199
1.74
2.35
2.6
3.1
—
—
—
0
0
97
720
1.39
2.34
1.6
1.6
—
—
—
0
0
221
1848
1.27
2.32
1.8
1.6
1.38
1.35
mmol/l
0.18
182
1528
69
482
1.47
2.31
2.4
3.0
4.14
6.73
e9/l
1.04
46
388
166
1340
1.30
2.30
2.6
3.0
2.45
2.46
mmol/l
0.22
137
1174
52
344
1.55
2.25
5.9
8.8
—
—
—
0
0
18
86
2.12
2.24
1.2
1.3
—
—
—
0
0
220
1849
1.26
2.20
3.4
3.0
—
—
—
0
0
13
54
2.43
2.20
1.2
1.1
—
—
—
0
0
225
1901
1.25
2.15
3.3
3.0
0.39
0.45
e6/l
0.21
172
1464
15
68
2.23
2.12
1.1
1.4
4586.78
220180.42
e6/l
—
9
45
69
493
1.44
2.08
1.4
1.4
—
—
—
0
0
135
1077
1.30
2.04
2.9
2.8
3.06
3.29
e6/l
0.09
74
579
18
90
2.02
2.01
1.2
1.3
—
0.74
nmol/l
—
0
7
25
142
1.78
1.94
3.2
2.5
13.66
16.22
%
1.98
16
77
278
2427
1.22
1.93
3.9
3.6
55.85
93.97
e6/l
0.77
194
1749
80
597
1.38
1.90
1.6
1.4
—
—
—
0
0
181
1518
1.25
1.83
4.2
4.1
1.02
1.02
kg/l
0.27
28
218
20
108
1.87
1.83
1.4
1.5
—
—
—
0
0
14
66
2.14
1.82
1.5
1.4
—
—
—
0
0
12
53
2.28
1.81
1.3
1.5
—
—
—
0
0
101
788
1.32
1.81
2.2
2.4
1.81
1.81
%
0.00
89
696
9
35
2.59
1.80
2.3
1.3
113.11
150.27
nmol/l
—
9
35
241
2087
1.22
1.80
3.4
3.1
18.01
66.22
e6/l
3.88
185
1631
36
232
1.58
1.79
1.0
1.1
—
—
—
0
0
215
1842
1.23
1.78
4.2
3.5
—
—
—
0
0
20
109
1.86
1.78
1.2
1.4
—
—
—
0
0
252
2195
1.21
1.77
2.8
3.1
6.27
7.05
mmol/l
2.38
209
1842
216
1855
1.22
1.75
4.3
4.1
0.00
0.00
estimate
0.50
73
647
26
155
1.70
1.74
2.9
2.3
117.90
128.47
g/l
0.96
20
121
7
24
2.93
1.72
1.3
1.3
424.06
80.03
nmol/l
—
7
17
118
949
1.28
1.70
2.0
1.7
—
—
—
0
0
8
31
2.60
1.66
4.6
2.6
52575.00
39125.97
ug/l
—
8
31
21
120
1.77
1.63
1.5
1.2
—
—
—
0
0
10
42
2.40
1.62
4.1
1.9
—
—
—
0
0
15
77
1.97
1.60
1.2
1.3
345.40
307.29
pmol/l
0.16
15
72
93
731
1.31
1.60
4.0
4.1
—
—
—
0
0
17
92
1.87
1.57
3.1
1.5
31.24
32.22
pg
0.30
17
92
15
78
1.94
1.55
1.5
1.8
—
—
—
0
0
35
233
1.52
1.54
1.7
1.6
—
—
—
0
0
173
1472
1.22
1.53
5.4
5.1
2.53
2.95
ug/l
0.35
156
1298
79
614
1.32
1.48
2.9
3.4
2.09
2.00
mmol/l
0.09
69
502
31
203
1.55
1.47
1.2
1.1
—
—
—
0
0
27
172
1.59
1.44
1.2
1.3
314.39
250.69
miu/ml
—
8
77
101
815
1.27
1.43
7.2
6.0
104.58
104.10
mmol/l
0.57
101
815
9
39
2.32
1.43
5.3
6.3
—
—
—
0
0
55
407
1.38
1.42
1.3
1.4
—
—
—
0
0
15
81
1.87
1.40
1.1
1.3
—
—
—
0
0
235
2075
1.19
1.40
3.0
3.2
377.26
387.79
mg/l
0.01
127
1295
82
651
1.29
1.33
1.5
1.5
—
—
—
0
0
11
54
2.05
1.33
3.6
2.3
13.15
13.12
%
0.04
11
54
72
562
1.31
1.33
3.4
3.5
—
—
—
0
0
246
2192
1.17
1.31
3.5
3.8
9.53
7.89
mg/mmol
0.19
136
1347
9
43
2.10
1.30
2.0
1.1
—
—
—
0
0
5
18
2.79
1.28
1.2
1.2
—
—
—
0
0
12
62
1.95
1.28
3.3
2.5
—
—
—
0
0
78
620
1.29
1.27
2.9
3.4
5.93
5.81
kpa
0.40
78
599
16
92
1.75
1.25
1.3
1.2
—
—
—
0
0
25
163
1.55
1.24
5.7
4.4
—
—
—
0
0
5
19
2.64
1.21
1.4
1.1
286.26
138.98
iu/ml
—
5
19
27
181
1.51
1.19
2.0
2.5
—
—
—
0
0
168
1461
1.19
1.19
2.6
2.5
4.61
6.75
e6/l
1.59
151
1339
6
26
2.32
1.19
3.5
1.5
—
—
—
0
0
11
57
1.94
1.17
1.2
1.2
—
—
—
0
0
66
520
1.29
1.16
5.7
7.9
—
—
—
0
0
5
20
2.51
1.15
1.2
1.6
—
—
—
0
0
163
1422
1.18
1.12
3.1
2.8
521.46
528.86
mosm/kgh2o
0.17
140
1242
99
824
1.23
1.11
1.5
1.6
—
—
—
0
0
109
917
1.22
1.10
5.4
4.9
1.08
1.04
mmol/l
0.49
102
830
8
41
1.96
1.09
1.5
1.9
—
—
—
0
0
65
517
1.28
1.08
3.8
4.1
0.88
0.64
%
0.31
25
174
23
153
1.52
1.07
1.3
1.2
—
—
—
0
0
39
288
1.37
1.07
1.2
1.2
—
—
—
0
0
7
33
2.13
1.05
1.6
3.5
415.57
1168.70
u/ml
—
7
33
15
90
1.68
1.04
1.6
2.6
—
—
—
0
0
9
46
1.97
1.03
1.3
1.2
—
—
—
0
0
7
34
2.07
1.03
1.6
1.5
—
—
—
0
0
7
34
2.07
1.03
1.1
1.3
—
—
—
0
0
39
291
1.36
1.01
2.4
2.2
10.67
12.09
nmol/l
0.46
33
260
235
2132
1.14
0.97
4.4
3.8
—
—
—
0
0
13
77
1.70
0.95
1.5
1.2
—
—
—
0
0
16
101
1.60
0.94
3.1
1.7
—
—
—
0
0
6
27
2.23
0.93
1.7
1.2
—
1.86
%
—
0
7
74
612
1.23
0.91
5.4
3.7
—
—
—
0
0
6
29
2.08
0.89
3.3
4.4
—
—
—
0
0
8
42
1.91
0.88
1.1
1.8
41.31
38.19
%
—
8
42
241
2203
1.13
0.88
2.5
2.3
—
—
—
0
0
21
144
1.47
0.88
1.2
1.7
—
—
—
0
0
70
578
1.23
0.88
3.8
4.2
0.83
1.10
%
0.63
30
210
56
454
1.25
0.83
1.9
1.6
—
—
—
0
0
12
73
1.65
0.82
1.1
1.1
—
—
—
0
0
185
1671
1.14
0.81
2.5
2.2
—
—
—
0
0
13
81
1.61
0.81
3.0
3.9
—
—
—
0
0
12
74
1.63
0.78
1.1
1.1
—
—
—
0
0
6
34
1.77
0.76
2.8
2.7
—
—
—
0
0
24
175
1.38
0.75
1.8
2.3
12.90
12.07
mg/l
0.28
24
163
69
581
1.20
0.74
2.7
2.4
7.18
7.81
ug/l
0.09
57
507
56
462
1.23
0.73
1.1
1.2
120.19
148.09
iu/ml
0.30
21
178
9
56
1.61
0.72
1.0
1.2
—
—
—
0
0
5
26
1.93
0.70
1.4
1.3
—
19.83
—
0
6
10
61
1.65
0.68
1.0
1.1
—
—
titre
—
0
0
70
596
1.19
0.68
3.9
3.7
1.23
1.23
mmol/l
0.11
62
502
37
294
1.27
0.67
1.7
1.9
0.54
1.50
ug/l
1.64
32
256
5
28
1.79
0.66
1.2
1.1
—
—
—
0
0
16
111
1.45
0.66
1.7
2.1
61.29
59.79
%
0.08
16
111
24
180
1.34
0.65
1.3
1.6
—
—
—
0
0
11
70
1.58
0.65
2.6
2.2
—
—
—
0
0
5
29
1.73
0.64
2.6
1.2
—
—
—
0
0
5
29
1.73
0.64
2.2
1.8
27.40
55.60
ug/l
—
5
29
24
181
1.34
0.63
1.3
1.6
—
—
—
0
0
24
181
1.34
0.63
1.3
1.6
—
—
—
0
0
14
200
0.69
0.63
6.6
4.5
—
—
—
0
0
22
165
1.34
0.61
1.4
1.3
—
—
—
0
0
60
511
1.19
0.60
3.9
4.4
0.05
0.73
%
0.58
20
146
12
81
1.49
0.57
1.0
1.2
—
—
—
0
0
16
115
1.40
0.57
1.6
1.9
—
—
—
0
0
14
98
1.44
0.56
1.1
1.0
—
—
—
0
0
21
159
1.33
0.55
1.5
2.1
682.90
3713.08
u/l
—
7
59
9
60
1.51
0.54
1.1
1.3
—
—
—
0
0
14
99
1.42
0.54
1.3
1.2
—
—
—
0
0
9
62
1.46
0.53
3.9
3.1
56.11
54.05
%
—
9
55
39
324
1.21
0.52
1.1
1.1
—
76.57
—
0
7
23
179
1.29
0.51
1.3
1.6
—
—
—
0
0
18
135
1.34
0.51
3.7
2.7
—
—
—
0
0
19
144
1.33
0.51
3.3
3.5
—
—
—
0
0
12
84
1.43
0.49
1.4
2.0
88.83
89.81
%
0.28
12
84
48
410
1.18
0.48
2.4
3.0
134.79
126.41
g/l
3.01
48
399
29
235
1.24
0.48
1.8
2.0
19.91
21.31
s
1.43
23
214
7
46
1.53
0.48
1.4
1.0
—
—
—
0
0
19
147
1.30
0.45
2.7
3.3
0.74
0.84
nmol/l
—
10
110
218
2310
0.92
0.45
3.4
2.9
—
—
—
0
0
7
50
1.40
0.45
1.1
1.1
—
—
—
0
0
189
1771
1.09
0.44
1.4
1.4
—
—
—
0
0
13
95
1.37
0.44
1.1
1.1
—
—
—
0
0
20
157
1.28
0.43
2.3
1.7
4.28
3.42
iu/l
—
9
51
18
140
1.29
0.42
1.7
2.7
—
—
—
0
0
61
539
1.14
0.42
3.9
4.3
0.19
0.11
%
0.32
21
172
10
70
1.43
0.42
1.0
1.0
—
—
—
0
0
14
105
1.34
0.41
1.1
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
5
34
1.47
0.40
1.4
1.4
127.20
162.23
mmol/24h
—
5
34
14
106
1.33
0.39
1.1
1.3
330.57
247.78
u/ml
—
7
61
14
106
1.33
0.39
2.0
1.6
42.29
42.05
nmol/l
0.01
14
100
9
66
1.37
0.38
1.1
1.4
—
—
—
0
0
5
36
1.39
0.38
4.8
2.3
—
—
—
0
0
37
318
1.17
0.37
2.2
1.7
—
—
—
0
0
15
116
1.30
0.37
1.5
1.5
—
—
—
0
0
6
43
1.40
0.35
1.0
1.0
277.00
292.20
mg/l
—
6
35
6
43
1.40
0.35
1.8
3.4
—
—
—
0
0
41
359
1.15
0.34
3.8
3.6
—
—
—
0
0
6
45
1.34
0.34
2.2
3.6
75.67
104.96
nmol/l
—
6
45
83
761
1.10
0.33
3.7
4.2
6.18
23.80
ug/l
0.99
66
628
21
173
1.22
0.33
1.3
1.6
—
—
—
0
0
54
485
1.12
0.31
2.5
3.1
—
—
—
0
0
12
93
1.29
0.30
1.1
1.2
—
—
—
0
0
32
278
1.16
0.30
2.3
3.2
83.22
1224.65
u/ml
1.11
27
238
89
825
1.09
0.29
3.3
3.0
0.72
0.80
ug/l
0.39
61
558
50
453
1.11
0.26
5.1
3.8
7.43
7.41
ph
—
10
57
15
123
1.22
0.25
2.3
2.7
—
—
—
0
0
9
74
1.22
0.25
1.6
1.2
—
—
—
0
0
20
170
1.18
0.24
1.4
1.6
—
—
—
0
0
18
211
0.85
0.23
14.2
9.8
—
—
—
0
0
28
247
1.14
0.23
2.6
2.8
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
7.00
—
0
5
0
10
0.00
0.21
0.0
5.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
20
173
1.16
0.21
1.0
1.1
—
—
—
0
0
10
80
1.25
0.20
1.2
1.1
—
—
—
0
0
6
48
1.25
0.20
1.5
1.9
14.48
10.41
%
—
6
48
34
375
0.90
0.20
2.4
2.7
0.09
0.20
e6/l
1.59
34
367
6
53
1.13
0.18
1.3
1.2
1.54
1.50
nmol/l
—
6
46
7
61
1.15
0.17
1.3
1.2
—
—
—
0
0
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
27
244
1.11
0.16
5.2
3.7
1.49
1.30
mmol/l
0.43
27
239
8
71
1.13
0.16
1.4
1.6
—
—
—
0
0
90
863
1.05
0.13
1.5
1.3
—
—
—
0
0
16
180
0.89
0.13
1.9
3.6
1.23
1.65
mg/l
2.00
16
161
15
134
1.12
0.11
1.4
1.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.4
1.45
1.02
g/l
—
5
48
7
65
1.08
0.08
1.3
1.1
—
—
—
0
0
7
68
1.03
0.08
1.0
1.3
5.31
6.78
mmol/l
—
7
61
32
337
0.95
0.07
1.4
1.4
—
—
—
0
0
46
479
0.96
0.07
1.4
1.3
—
—
—
0
0
9
87
1.03
0.07
1.2
1.9
—
—
—
0
0
22
209
1.05
0.04
1.6
1.3
—
—
—
0
0
15
140
1.07
0.04
1.7
4.0
2.17
3.12
mmol/l
—
9
92
62
633
0.98
0.03
1.4
1.4
—
—
—
0
0
10
92
1.09
0.03
1.5
2.3
—
—
—
0
0
25
258
0.97
0.02
6.0
4.1
—
—
—
0
0
14
134
1.05
0.00
2.6
3.3
55.50
59.70
%
0.50
14
134
12
117
1.03
0.00
1.2
1.4
—
—
—
0
0
12
122
0.98
0.00
1.8
1.3
—
—
—
0
0
13
129
1.01
0.00
2.7
3.1
4.34
4.37
e9/l
0.02
13
129
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
5.7
—
0.15
—
0
7
7
71
0.99
-0.00
5.3
2.4
—
—
—
0
0
7
74
0.95
-0.00
1.3
1.6
—
—
—
0
0
8
88
0.91
-0.00
1.5
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
7.63
—
0
8
0
8
0.00
-0.00
0.0
6.4
—
—
—
0
0
9
97
0.93
-0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
18.27
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
16.40
—
0
6
7
73
0.96
-0.00
1.1
1.1
1.28
1.47
g/l
—
7
68
0
5
0.00
-0.00
0.0
1.2
—
0.04
—
0
5
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
9
97
0.93
-0.00
3.9
3.6
4.56
1.31
%
—
9
90
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
87
0.92
-0.00
2.6
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
33
330
1.00
-0.00
5.4
3.9
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
188.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_EPIPHORA and mortality.

Females

Parameter HR [95% CI] p-value
H7_EPIPHORA 0.846 [0.73, 0.98] 0.023
Birth year 0.995 [0.99, 1.0] 0.288

During the follow-up period (1.1.1998 — 31.12.2019), 339 out of 2954 females with H7_EPIPHORA died.

Males

Parameter HR [95% CI] p-value
H7_EPIPHORA 0.996 [0.84, 1.18] 0.961
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 302 out of 1479 males with H7_EPIPHORA died.

Mortality risk

Mortality risk for people of age

years, who have H7_EPIPHORA.

N-year risk Females Males
1 0.104% 0.193%
5 0.536% 1.29%
10 1.339% 3.071%
15 2.565% 5.718%
20 4.456% 9.408%

Relationships between endpoints

↥

Index endpoint: H7_EPIPHORA – Epiphora

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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