Melanocytic naevi of lower limb, including hip

CD2_BENIGN_MELANOCYTIC_LOWERLIMB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.7&
  • Hospital discharge: ICD-9 2167A
  • Cause of death: ICD-10 D22.7&
  • Cause of death: ICD-9 2167A

2 out of 7 registries used, show all original rules.

1744

4. Check minimum number of events

None

1744

5. Include endpoints

None

1744

6. Filter based on genotype QC (FinnGen only)

1705

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) coxae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10634 6739 3862
Only index persons 9877 6347 3530
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.11
Only index persons 0.20 0.23 0.13
Median age at first event (years)
Whole population 39.83 41.13 37.49
Only index persons 41.39 42.30 39.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1705 1163 542
Unadjusted period prevalence (%) 0.36 0.41 0.25
Median age at first event (years) 52.02 48.78 58.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1744
Matched controls
17440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
4055.1
307.7
1664
89
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
64.0
307.7
754
205
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
10.5
307.7
446
552
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.3
307.7
583
807
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
9.0
301.9
431
612
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
7.6
193.5
304
471
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.7
166.2
292
506
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
55.1
156.5
89
17
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
11.1
140.9
155
152
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
30.4
126.9
84
29
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.1
125.9
301
687
XQ845
NOMESCO Finland
Dermatoscopy
11.8
119.7
125
113
L57.0
ICD-10 Finland
Actinic keratosis
4.6
115.8
320
819
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
21.7
110.8
83
40
TQW99
NOMESCO Finland
Other minor procedure on skin
6.0
107.3
204
377
R23.8
ICD-10 Finland
Other and unspecified skin changes
3.3
105.7
545
2123
XQ848
NOMESCO Finland
Dermatological photography
8.0
105.5
149
201
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
29.6
90.0
60
21
2167A
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,NAEVUS PIGMENTOSUS]
+∞
87.2
83
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
7.5
82.0
121
171
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
9.6
82.0
98
107
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
9.7
81.6
97
105
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
27.0
80.0
55
21
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
26.0
76.0
53
21
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.3
67.4
186
468
9733
FHL
Excision of skin change in operating room or anesthesia
9.9
67.0
78
82
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.6
66.8
111
178
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
13.9
66.7
62
46
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
23.6
63.7
46
20
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
16.0
61.6
53
34
D03.5
ICD-10 Finland
Melanoma in situ of trunk
20.5
57.5
44
22
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
13.2
57.3
55
43
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
6.7
57.0
92
143
S18
ICPC
Laceration/cut
2.2
54.4
891
5656
127
Kela drug reimbursment
Transplant complication
8.6
53.4
69
83
D22
ICD-10 Finland
Melanocytic naevi
3.8
52.0
173
496
L82
ICD-10 Finland
Seborrhoeic keratosis
2.5
49.4
391
1821
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
11.4
48.6
51
46
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
5.7
48.0
91
166
L04AA06
ATC
mycophenolic acid; systemic
7.0
47.7
74
110
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
9.6
45.5
54
58
ZXC50
NOMESCO Finland
Cryotherapy
5.3
45.3
94
186
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
58.3
43.6
51
9
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
6.6
41.9
68
106
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
68.9
41.2
47
7
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
12.3
41.1
41
34
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
16.5
40.1
34
21
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
6.4
38.3
64
103
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.4
37.7
75
143
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.5
37.0
132
395
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.2
36.7
77
154
Z94.0
ICD-10 Finland
Kidney transplant status
8.6
36.6
47
56
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
11.8
36.1
37
32
ZZR00
NOMESCO Finland
Flap of skin
5.5
35.1
69
130
Z2221
NOMESCO Finland
Medical doctor
1.9
33.9
549
3326
PJA12
NOMESCO Finland
Sentinel node biopsy
2.7
32.9
192
763
ZXC15
NOMESCO Finland
Use of photodynamic technique
6.9
29.8
46
68
C43.79
ICD-10 Finland
Malignant melanoma of the lower extremity including hip or other unspecified histology
30.6
29.5
39
13
L04AD02
ATC
tacrolimus; systemic
7.8
29.0
40
52
S82
ICPC
Naevus/mole
2.2
28.9
289
1459
L04AA01
ATC
[U] ciclosporin
6.7
28.2
45
69
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.7
27.6
35
41
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
5.6
27.3
52
95
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
10.5
26.3
29
28
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
10.5
26.3
29
28
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.1
26.2
55
110
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
7.3
25.9
38
53
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
8.6
25.8
33
39
B07.9
ICD-10 Finland
Verruca simplex
3.5
25.5
91
272
ZZA00
NOMESCO Finland
Split skin graft
4.1
25.5
72
183
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
5.5
23.4
45
83
L04AX01
ATC
azathioprine; systemic
3.1
23.1
98
326
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
18.8
23.1
35
19
ZXC20
NOMESCO Finland
Use of chemical agents
4.9
23.0
51
107
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
7.5
22.9
33
45
L04AD01
ATC
ciclosporin; systemic
4.6
22.7
54
120
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
4.9
22.5
50
105
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
21.6
650
4596
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
8.8
21.6
27
31
ZQZ00
NOMESCO Finland
Treatment of several skin areas
17.7
21.4
33
19
TQW80
NOMESCO Finland
Local dermatologic skincare
3.9
21.1
63
167
E0000UV, ,
ATC
1.6
20.7
735
5403
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
20.5
607
4260
A12AA04
ATC
calcium carbonate; oral
5.3
20.4
41
79
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
27.4
20.0
27
10
D06BB10
ATC
imiquimod; topical
2.7
19.9
112
435
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
74.4
19.7
22
*
SPAT1153
SPAT
Removal of sutures
1.7
19.7
521
3548
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.9
19.6
30
44
S21
ICPC
Skin texture symptom/complaint
1.9
19.5
258
1430
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.4
19.0
48
112
S29
ICPC
Skin symptom/complaint other
1.8
17.9
332
2045
A11CC03
ATC
alfacalcidol; systemic
4.0
17.9
51
131
ZXA05
NOMESCO Finland
Left side
1.7
17.8
396
2565
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
20.3
17.8
26
13
Z3231
NOMESCO Finland
Registered nurse
1.6
17.5
461
3119
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.7
17.0
95
368
S77
ICPC
Malignant neoplasm of skin
5.6
17.0
32
58
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
25.9
16.9
23
9
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.4
16.9
33
62
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
20.3
16.4
24
12
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.1
16.4
68
224
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.3
16.1
60
185
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
13.7
16.0
27
20
TQW40, ,
SPAT
2.2
15.9
137
647
ZXE00
NOMESCO Finland
One hour or less
1.5
15.7
656
4920
C43.7
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of lower limb, including hip
17.4
15.6
24
14
C43
ICD-10 Finland
Malignant melanoma of skin
22.3
15.5
22
10
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
13.9
15.5
26
19
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
38.4
15.4
19
5
R4110
NOMESCO Finland
Physiotherapy
1.6
15.3
451
3121
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
28.9
15.2
20
7
ZXA00
NOMESCO Finland
Right side
1.6
14.8
414
2826
L91.0
ICD-10 Finland
Hypertrophic scar
4.2
14.7
39
95
QDE00
NOMESCO Finland
Excision of loose skin or fold of skin from lower limb
+∞
14.6
14
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
14.5
349
2296
B03XA01
ATC
erythropoietin; parenteral
6.0
14.3
25
42
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
19.3
14.2
21
11
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.5
14.1
88
360
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
17.7
13.8
21
12
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.9
13.8
30
62
137
Kela drug reimbursment
Uraemia requiring dialysis
5.7
13.7
25
44
N18.0
ICD-10 Finland
End-stage renal disease
5.9
13.5
24
41
C43.51
ICD-10 Finland
Malignant melanoma of the trunk originating in lentigo maligna
34.3
13.5
17
5
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
13.9
13.2
22
16
D18.0
ICD-10 Finland
Haemangioma, any site
3.2
13.2
53
171
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
13.2
694
5404
J01DB01
ATC
cefalexin; oral
1.6
13.1
1408
12622
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
5.1
12.9
27
54
8090/3-C44.7
ICD-O-3
Basal cell carcinoma, NOS, of skin of lower limb and hip
14.2
12.8
21
15
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
3.1
12.5
53
177
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
6.2
12.5
21
34
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
12.4
413
2921
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
12.2
467
3398
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
2.9
12.2
57
201
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.7
12.0
22
39
J01MA02
ATC
ciprofloxacin; systemic
1.5
11.7
584
4474
TQW40
NOMESCO Finland
Remowal of suture of skin
2.0
11.5
120
611
TK800
NOMESCO Finland
Hemodialysis
3.4
11.3
39
115
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.8
11.0
20
35
UJF32
NOMESCO Finland
Coloscopy
1.5
11.0
390
2786
D22.0
ICD-10 Finland
Melanocytic naevi of lip
14.0
11.0
18
13
C43.61
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder originating in lentigo maligna
43.6
10.9
13
*
ZXA10
NOMESCO Finland
Bilateral
1.6
10.6
281
1879
J02AC01
ATC
fluconazole; systemic
1.4
10.6
679
5425
DAB00
NOMESCO Finland
Excision of lesion of auricle
4.8
10.5
23
48
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.0
10.5
45
152
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
2.6
10.4
61
243
Z3226
NOMESCO Finland
Physiotherapist
1.6
10.4
287
1938
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
12.1
10.3
18
15
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
10.2
163
954
I78.1
ICD-10 Finland
Naevus, non-neoplastic
2.9
10.2
46
160
C43.53
ICD-10 Finland
Malignant melanoma of the torso nodular
13.2
10.2
17
13
8090/3-C44.6
ICD-O-3
Basal cell carcinoma, NOS, of skin of upper limb and shoulder
11.4
10.1
18
16
S26
ICPC
Fear of cancer of skin
4.0
10.1
28
71
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
3.0
9.9
42
141
N18.8
ICD-10 Finland
Other chronic renal failure
3.3
9.9
36
110
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
26.2
9.8
13
5
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
9.7
149
862
Z94.4
ICD-10 Finland
Liver transplant status
13.4
9.7
16
12
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
2.8
9.6
46
165
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
15.1
9.5
15
10
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
9.5
73
330
8743/3-C44.7
ICD-O-3
Low cumulative sun damage melanoma of skin of lower limb and hip
30.2
9.4
12
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
9.3
593
4704
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
9.2
100
517
JN4BD
NOMESCO Finland
Extensive body CT
1.8
9.0
147
865
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
15.7
9.0
14
9
C44
ICD-10 Finland
Other malignant neoplasms of skin
12.6
8.9
15
12
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
4.9
8.8
19
39
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
9.5
8.8
17
18
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
7.2
8.7
20
28
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
8.7
325
2335
D06BX02
ATC
ingenol mebutate; topical
4.1
8.7
23
56
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
8.7
196
1259
C43.49
ICD-10 Finland
Malignant melanoma of the scalp and neck other or unspecified histology
50.2
8.7
10
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
8.6
389
2901
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.6
8.6
27
75
5AB14, ,
NOMESCO Finland
16.4
8.6
13
8
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
4.1
8.5
23
57
DHB00
NOMESCO Finland
Excision of lesion of external nose
4.3
8.4
21
49
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
8.4
321
2319
C44.60
ICD-10 Finland
Malignant tumor of the skin of the upper extremity including the shoulder without histology
+∞
8.3
8
*
WX402
NOMESCO Finland
General anaesthesia
1.5
8.3
332
2416
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
14.5
8.2
13
9
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
14.5
8.2
13
9
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.3
8.2
63
285
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
6.5
8.2
20
31
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
3.9
8.2
23
59
L04AA05
ATC
[U] tacrolimus
17.3
8.1
12
7
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
7.3
8.0
18
25
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
7.3
8.0
18
25
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
7.9
117
669
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
7.9
169
1072
QDA10
NOMESCO Finland
Incision of skin of lower limb
4.7
7.9
18
39
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.8
1473
13718
Z31.5
ICD-10 Finland
Genetic counselling
1.9
7.8
95
511
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
2.1
7.8
68
324
QBA10
NOMESCO Finland
Incision of skin of trunk
3.8
7.8
23
61
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
7.8
296
2134
A02BC01
ATC
omeprazole; systemic
1.4
7.7
401
3057
8743/3-C44.5
ICD-O-3
Low cumulative sun damage melanoma of skin of trunk
45.2
7.7
9
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
7.6
103
573
QDE15
NOMESCO Finland
Excision of other superficial lesion of skin in lower limb
18.4
7.6
11
6
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
7.6
105
589
C44.70
ICD-10 Finland
Malignant tumor of the skin of the lower extremity including the hip without histology
25.1
7.6
10
*
B03XA02
ATC
darbepoetin alfa; parenteral
2.9
7.6
35
124
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.0
7.5
32
108
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.9
7.5
100
555
R4120
NOMESCO Finland
Occupational therapy
1.8
7.5
102
570
UJH02
NOMESCO Finland
Anoscopy
2.1
7.4
66
317
S08
ICPC
Skin colour change
2.0
7.4
81
420
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
7.4
87
463
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.0
7.4
32
109
D01AE16
ATC
amorolfine; topical
1.6
7.3
168
1083
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
8.4
7.3
15
18
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
7.2
190
1265
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.2
281
2031
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.2
415
3215
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.2
7.2
60
282
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
20.1
7.1
10
5
M81.5
ICD-10 Finland
Idiopathic osteoporosis
4.2
7.0
18
43
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.7
7.0
126
764
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
7.0
331
2480
ZX108
NOMESCO Finland
Inhalation
5.5
6.9
19
35
L72.1
ICD-10 Finland
Trichilemmal cyst
1.8
6.9
103
592
XKD00
NOMESCO Finland
Uroflowmetry
1.6
6.9
165
1076
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.9
467
3711
D07AC01
ATC
betamethasone; topical
1.3
6.8
539
4383
Z2446
NOMESCO Finland
Social worker
1.8
6.8
108
633
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.8
192
1301
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.8
627
5212
A12AA12
ATC
[U] calcium acetate
16.8
6.7
10
6
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.0
6.7
71
365
Z08.9
ICD-10 Finland
Follow-up examination after unspecified treatment for malignant neoplasm
7.2
6.7
15
21
C43.5
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of trunk
7.2
6.7
15
21
D07AB08
ATC
desonide; topical
1.6
6.7
166
1091
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.2
6.6
52
238
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
2.9
6.6
29
100
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.6
222
1560
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
6.6
83
453
QDE20
NOMESCO Finland
Excision and repair of scar or web of skin of lower limb
8.7
6.6
13
15
D07XC01
ATC
betamethasone; topical
1.6
6.5
168
1114
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
6.5
132
827
M05BA04
ATC
alendronic acid; oral
1.7
6.4
110
658
D01AE15
ATC
terbinafine; topical
1.8
6.4
95
545
A54
ICPC
General and Unspecified, Repair/fix-suture/cast/prosth device
2.6
6.4
34
130
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
14.4
6.4
10
7
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.4
316
2384
V03AE01
ATC
polystyrene sulfonate; oral
3.8
6.4
19
51
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
6.4
672
5673
C44.91
ICD-10 Finland
Unspecified localization of basocellular carcinoma of the skin
6.6
6.3
15
23
9734
FHL
Excision and local plastic or associated free skin grafting
6.0
6.3
16
27
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
18.1
6.3
9
5
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
18.1
6.3
9
5
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
6.3
6
*
3024
Kela drug reimbursment
Dabrafenib and trametinib (adjuvant treatment)
26.8
6.2
8
*
C43.40
ICD-10 Finland
Malignant melanoma of the scalp and neck without histology
26.8
6.2
8
*
1509
Kela drug reimbursment
Dabrafenib (adjuvant treatment)
26.8
6.2
8
*
C43.00
ICD-10 Finland
Malignant melanoma of the lip without histology
26.8
6.2
8
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.5
6.2
38
156
205
Kela drug reimbursment
Chronic hypertension
1.4
6.2
308
2324
ZX120
NOMESCO Finland
Intravenous
1.6
6.2
135
862
J05AB01
ATC
aciclovir; systemic
1.4
6.2
335
2566
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.0
6.1
60
300
QXE99
NOMESCO Finland
Other excision or repair of unspecified region of skin
12.6
6.1
10
8
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.5
6.0
35
140
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
5.2
6.0
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
520
1839
3.60
119.64
1.8
1.3
—
—
—
0
0
1054
5900
2.99
106.65
3.5
2.0
—
—
—
0
0
196
599
3.56
53.65
1.4
1.2
—
—
—
0
0
262
1203
2.39
33.16
1.5
1.4
—
—
—
0
0
39
61
6.52
23.96
24.9
31.5
87.10
122.05
ug/l
3.29
31
52
935
7323
1.60
19.94
8.5
5.8
0.04
0.04
e9/l
1.68
827
6398
931
7314
1.59
19.37
8.5
5.8
0.55
0.56
e9/l
0.83
825
6396
958
7578
1.59
19.33
8.7
6.1
0.18
0.19
e9/l
0.11
850
6717
953
7543
1.58
19.07
8.5
5.8
1.91
1.93
e9/l
0.19
862
6734
879
6866
1.56
18.36
8.9
6.3
—
—
—
0
0
676
4973
1.59
18.35
5.3
3.5
80.70
100.06
e6/l
0.21
465
3430
1036
8457
1.55
17.35
11.5
8.9
3.96
4.03
e9/l
0.39
922
7439
363
2313
1.72
17.26
3.3
2.6
2.25
1.11
e6/l
0.46
217
1285
1456
12926
1.77
17.03
20.5
15.4
14.51
14.67
%
0.53
1435
12690
535
3801
1.59
16.44
4.5
3.0
0.24
0.44
e6/l
2.46
410
2864
555
4014
1.56
15.63
6.5
3.8
7.40
7.40
ph
0.71
92
778
755
5850
1.51
15.41
6.8
4.7
36.68
35.94
g/l
3.76
700
5473
848
6785
1.49
14.49
8.9
6.6
1.22
1.21
mmol/l
0.78
734
5798
768
6039
1.49
14.22
2.7
2.3
78.62
76.23
nmol/l
1.67
710
5482
514
3745
1.53
13.64
4.6
2.9
—
—
—
0
0
198
1131
1.85
13.48
11.8
7.6
10.21
8.87
mmol/l
1.69
191
1086
1250
10903
1.52
13.33
10.1
7.2
75.55
77.23
u/l
0.86
1191
10300
557
4156
1.50
13.10
4.8
3.1
40.34
79.26
e6/l
0.98
430
3181
489
3563
1.52
12.84
5.3
3.7
90.92
92.78
%
0.91
474
3468
1227
10697
1.50
12.80
5.0
4.0
10.29
11.42
mm/h
2.45
1148
9934
1139
9791
1.47
12.70
3.9
3.5
—
—
—
0
0
326
2173
1.62
12.66
3.7
2.8
3.40
2.96
e6/l
0.27
180
1150
818
6647
1.43
12.07
9.0
5.9
0.73
0.67
%
2.33
763
6239
801
6486
1.43
12.04
12.2
9.1
0.00
0.00
e9/l
0.00
666
5320
24
46
5.28
12.02
2.7
2.7
—
—
—
0
0
764
6145
1.43
11.85
7.9
6.0
1.22
1.21
mmol/l
1.04
709
5625
840
6874
1.43
11.84
8.9
5.9
2.82
2.81
%
0.01
785
6468
494
3672
1.48
11.56
9.0
6.7
—
—
—
0
0
854
7031
1.42
11.52
8.7
5.7
56.88
56.88
%
0.00
799
6639
453
3312
1.50
11.50
3.7
3.5
—
—
—
0
0
841
6910
1.42
11.45
9.1
6.1
8.34
8.37
%
0.11
787
6512
863
7127
1.42
11.39
8.9
5.9
28.45
28.53
%
0.08
810
6734
401
2874
1.51
11.16
3.8
2.5
5.38
6.67
e6/l
1.08
366
2577
1301
11597
1.48
11.12
4.7
4.1
14.68
14.63
pmol/l
0.26
1210
10680
1583
14767
1.78
10.99
18.0
14.4
139.67
139.61
mmol/l
0.46
1557
14385
873
7262
1.40
10.85
4.0
3.5
0.00
0.01
estimate
1.06
144
1342
864
7190
1.40
10.63
5.7
4.8
0.00
0.00
estimate
0.50
150
1375
256
1675
1.62
10.60
2.3
1.6
—
—
—
0
0
719
5811
1.40
10.44
3.5
3.2
6.06
5.87
ph
0.82
51
489
1583
14811
1.75
10.28
18.4
14.5
3.93
3.95
mmol/l
1.57
1557
14401
859
7179
1.39
10.11
4.0
3.5
0.00
0.00
estimate
0.75
160
1447
23
52
4.47
9.56
1.7
1.6
—
—
—
0
0
257
1727
1.57
9.47
9.8
5.8
1.06
1.04
mmol/l
0.42
245
1600
168
1016
1.72
9.38
5.9
3.7
103.21
80.83
ng/l
1.58
154
892
1141
10064
1.39
9.27
5.3
4.2
—
—
—
0
0
858
7232
1.37
9.27
8.0
6.0
11.60
11.18
umol/l
0.32
819
6871
305
2143
1.51
9.16
4.9
3.6
0.82
0.82
mmol/l
0.17
286
2019
676
5505
1.37
8.99
2.1
1.9
98.92
96.44
pmol/l
0.71
351
2869
1092
9595
1.37
8.88
4.9
4.2
3335.90
2310.43
e6/l
—
10
127
346
2511
1.47
8.84
3.8
3.5
477.59
471.60
ng/l
0.01
250
1817
461
3538
1.41
8.69
3.7
2.5
3104.13
5150.63
umol/l
0.61
413
3128
247
1677
1.55
8.67
1.9
1.4
—
—
—
0
0
602
4835
1.37
8.64
4.5
3.1
28.62
31.62
u/l
1.98
575
4607
1391
12754
1.45
8.62
21.5
16.4
332.29
332.48
g/l
0.37
1383
12662
586
4690
1.38
8.58
4.6
3.4
2.35
2.35
mmol/l
0.09
521
4178
1472
13651
1.50
8.56
5.6
4.8
1.79
1.96
mu/l
1.09
1383
12670
370
2753
1.44
8.24
4.2
2.7
515.97
537.49
mosm/kgh2o
1.25
321
2369
1702
16441
2.46
8.13
24.6
18.9
90.66
90.64
fl
0.07
1690
16238
334
2445
1.45
8.10
4.0
2.9
2.44
2.44
mmol/l
0.32
292
2158
1702
16443
2.46
8.09
24.5
18.9
30.21
30.20
pg
0.12
1690
16237
1702
16444
2.45
8.07
24.7
19.0
4.49
4.50
e12/l
0.22
1672
16028
1702
16444
2.45
8.07
24.7
19.0
6.55
6.67
e9/l
1.67
1673
16028
1701
16431
2.43
8.05
24.7
19.0
256.03
255.64
e9/l
0.09
1678
16057
295
2117
1.47
7.92
3.6
2.4
13.76
13.55
umol/l
0.21
286
1977
1702
16452
2.43
7.92
24.8
19.1
134.93
135.05
g/l
0.14
1693
16242
255
1780
1.51
7.84
3.9
2.4
23.84
23.10
%
0.37
232
1527
1631
15550
1.75
7.75
13.0
9.8
24.97
25.86
u/l
1.49
1603
15066
64
301
2.17
7.60
1.7
1.4
—
—
—
0
0
73
363
2.06
7.51
2.4
2.3
37.88
38.01
g/l
0.06
68
326
226
1552
1.52
7.50
1.5
1.3
—
—
—
0
0
1698
16423
2.29
7.43
24.8
19.1
40.18
40.38
%
0.27
1617
15474
269
1926
1.47
7.27
3.7
2.4
2.30
2.37
g/l
1.27
258
1791
87
466
1.91
7.27
1.3
1.4
10.74
10.14
u/l
0.12
71
375
1553
14665
1.54
7.24
17.2
12.9
21.07
22.15
mg/l
0.62
1186
11499
86
461
1.91
7.17
2.9
1.6
1.08
1.19
g/l
3.30
81
434
285
2070
1.45
7.15
2.5
2.1
29.50
29.62
s
0.14
275
2005
59
277
2.17
7.06
1.9
1.4
113.08
110.47
u/ml
0.07
12
50
1539
14533
1.50
6.87
5.1
4.6
2.76
2.80
mmol/l
0.95
1457
13532
155
999
1.61
6.79
2.8
2.8
66.45
66.88
g/l
0.30
149
919
394
3055
1.37
6.77
1.7
1.5
2.23
2.32
g/l
0.45
245
1890
1463
13702
1.42
6.64
4.0
3.7
1.22
1.27
mmol/l
2.23
1376
12706
139
877
1.64
6.64
2.2
2.1
11.11
12.17
nmol/l
0.79
128
786
98
562
1.79
6.62
2.4
2.2
21.83
21.17
s
0.45
89
490
226
1598
1.48
6.49
4.4
2.6
8.25
7.28
umol/l
0.40
201
1382
195
1339
1.51
6.46
2.8
2.3
33.88
72.07
u/l
0.55
175
1140
279
2055
1.43
6.46
1.5
1.3
475.47
551.48
titre
0.43
53
413
1619
15494
1.63
6.42
19.3
14.6
78.03
73.58
umol/l
4.04
1619
15489
132
832
1.63
6.34
2.6
2.5
—
—
—
0
0
1610
15395
1.60
6.32
14.4
12.0
—
—
—
0
0
200
1390
1.50
6.25
3.4
2.0
366.30
374.56
nmol/l
0.27
187
1283
552
4546
1.31
6.25
2.4
2.3
—
—
—
0
0
16
39
4.13
6.09
6.4
4.3
—
—
—
0
0
522
4302
1.30
5.80
3.0
2.9
—
—
—
0
0
165
1120
1.52
5.78
3.2
2.8
10.35
10.53
g/l
0.21
151
1022
18
50
3.63
5.76
1.1
1.2
—
—
—
0
0
781
6783
1.27
5.74
3.7
2.8
107.74
105.23
ug/l
0.11
730
6309
95
564
1.72
5.73
2.2
1.4
8.06
11.33
u/ml
—
8
11
51
247
2.10
5.70
5.8
3.2
—
—
—
0
0
258
1918
1.41
5.64
2.6
2.3
95.71
114.18
ug/g
0.68
210
1511
160
1085
1.52
5.63
8.3
9.1
—
—
—
0
0
72
400
1.83
5.45
2.1
2.9
—
—
—
0
0
8
5
16.07
5.41
5.4
3.0
19.36
19.00
mg/l
—
8
5
152
1030
1.52
5.37
1.3
1.3
166.23
214.79
u/ml
0.56
144
948
1508
14313
1.40
5.32
4.6
4.1
4.69
4.72
mmol/l
0.48
1436
13408
1501
14237
1.39
5.30
4.5
4.1
1.51
1.49
mmol/l
1.62
1426
13266
39
175
2.26
5.28
1.3
1.3
—
—
—
0
0
912
8124
1.26
5.23
5.5
4.8
6.49
6.62
mmol/l
1.11
852
7550
132
873
1.55
5.22
2.3
1.8
1.45
1.37
g/l
0.12
123
802
486
4020
1.29
5.16
2.2
2.1
184.69
213.25
u/l
0.35
452
3800
79
460
1.75
5.13
1.2
1.2
—
—
—
0
0
694
6000
1.26
5.12
16.7
13.2
1.18
1.21
inr
0.41
197
1807
16
36
4.48
5.05
1.0
1.8
1.64
1.83
ug/l
—
7
18
782
6873
1.25
4.94
2.7
2.5
—
—
—
0
0
37
168
2.23
4.89
1.4
1.6
—
—
—
0
0
40
189
2.14
4.81
2.9
2.5
—
—
—
0
0
417
3423
1.29
4.63
2.4
2.2
—
—
—
0
0
33
148
2.25
4.51
6.1
4.3
388.87
68.27
u/ml
0.41
12
43
129
879
1.50
4.48
1.3
1.4
22.33
27.40
iu/l
1.12
108
747
168
1215
1.42
4.30
5.4
3.7
1.55
1.93
mmol/l
0.96
151
1015
139
977
1.46
4.15
3.7
3.3
4.58
4.53
pmol/l
0.21
128
865
45
236
1.93
4.13
1.7
1.6
0.62
0.77
g/l
0.45
33
177
453
3806
1.26
4.10
1.7
1.6
1.36
1.37
mmol/l
0.10
400
3248
1461
13923
1.30
4.02
4.6
4.2
5.79
5.84
mmol/l
0.95
1373
12799
19
69
2.77
4.02
1.2
1.1
1465.00
1685.06
miu/ml
0.33
19
69
22
87
2.55
3.97
8.6
6.4
—
—
—
0
0
167
1225
1.40
3.96
5.2
3.7
5.89
5.84
kpa
0.33
161
1187
423
3540
1.26
3.95
2.5
2.1
2.75
2.92
mg/l
1.07
368
3019
72
442
1.66
3.93
3.4
1.6
0.21
0.24
g/l
1.69
67
416
189
1419
1.37
3.90
3.4
2.8
1.58
1.83
%
3.86
177
1272
139
992
1.44
3.85
1.5
1.4
—
—
—
0
0
250
1967
1.32
3.78
2.2
2.0
—
—
—
0
0
421
3537
1.25
3.78
1.4
1.3
1.08
1.58
u/ml
0.62
120
936
34
167
2.06
3.76
3.4
1.6
60.50
25.73
iu/ml
—
6
11
1371
12998
1.26
3.70
5.7
5.3
38.63
39.21
mmol/mol
1.59
1290
12140
116
806
1.47
3.70
6.4
8.6
24.43
24.81
mmol/l
0.75
116
800
86
561
1.56
3.69
2.6
2.0
1.21
1.47
g/l
2.11
78
490
54
315
1.74
3.58
1.5
1.3
293.29
249.35
u/ml
0.40
40
188
173
1306
1.36
3.47
3.8
4.2
3.21
21.77
ug/l
2.19
139
1061
156
1168
1.37
3.30
1.3
1.2
101.24
141.77
iu/ml
0.95
57
453
410
3483
1.23
3.29
5.1
4.2
—
—
—
0
0
100
697
1.46
3.18
2.4
2.4
—
—
—
0
0
93
639
1.48
3.18
1.1
1.1
—
—
—
0
0
371
3129
1.24
3.17
3.9
3.8
1.02
1.02
kg/l
0.21
49
452
97
674
1.47
3.13
1.6
1.6
287.12
302.00
mu/l
0.25
91
603
117
843
1.42
3.12
1.4
1.2
—
—
—
0
0
8
16
5.02
3.05
2.1
1.3
192.13
81.94
ng/l
—
8
16
8
16
5.02
3.05
1.9
4.6
—
—
—
0
0
78
523
1.51
3.01
1.5
1.3
—
—
—
0
0
47
279
1.70
2.98
3.6
3.5
—
—
—
0
0
138
1033
1.36
2.95
3.7
2.9
64.07
73.09
e9/l
2.98
100
780
236
1908
1.27
2.92
1.9
1.6
—
—
—
0
0
229
1846
1.28
2.90
3.3
3.0
0.69
0.75
ug/l
0.61
159
1188
14
52
2.71
2.89
3.4
2.1
68.93
69.37
ug/l
0.00
14
52
369
3147
1.22
2.82
5.1
4.8
2.03
2.45
ug/l
1.36
336
2834
56
355
1.60
2.78
4.2
3.7
72.39
64.36
mg/l
0.08
43
285
56
355
1.60
2.78
4.3
3.7
33.48
40.94
mg/l
0.31
43
286
364
3106
1.22
2.76
1.6
1.5
21.61
20.79
nmol/l
0.48
314
2669
24
118
2.05
2.72
2.4
2.2
—
—
—
0
0
133
1009
1.34
2.63
2.2
2.3
7.08
6.97
ug/l
0.02
115
897
142
1088
1.33
2.63
3.4
3.3
—
—
—
0
0
296
2486
1.23
2.62
1.3
1.3
9.49
11.35
u/ml
0.19
102
986
495
4366
1.19
2.62
3.7
2.5
65.62
77.14
u/l
0.25
457
4041
69
466
1.50
2.61
4.3
3.5
104.60
936.27
u/ml
1.32
54
400
20
93
2.16
2.61
2.4
3.0
40.43
44.00
%
—
7
54
386
3331
1.20
2.60
2.3
1.7
1.03
1.05
mg/l
0.05
281
2533
47
293
1.62
2.52
4.2
3.9
59.81
57.31
%
0.83
47
293
25
458
0.54
2.50
4.6
9.5
—
—
—
0
0
60
400
1.52
2.43
1.7
2.0
11.52
11.54
mg/l
0.01
55
370
394
3431
1.19
2.40
3.1
3.0
1398.96
1156.14
ng/l
0.48
329
2874
35
205
1.72
2.38
1.1
1.2
—
—
—
0
0
1056
9937
1.16
2.36
3.6
3.0
40.81
43.62
u/l
0.73
1000
9367
22
111
1.99
2.36
1.0
1.2
—
—
—
0
0
278
2347
1.22
2.35
1.7
1.7
1197.49
1183.47
nmol/l
0.09
214
1782
132
1020
1.32
2.33
4.3
3.1
4.74
4.61
kpa
0.31
127
988
45
284
1.60
2.32
3.8
3.6
4.03
4.15
e9/l
0.12
45
284
239
1993
1.23
2.28
1.4
1.2
—
—
—
0
0
20
99
2.03
2.26
2.8
4.0
11.70
10.73
%
0.46
20
99
22
114
1.94
2.20
1.9
1.5
0.99
0.96
g/l
0.15
22
114
382
3343
1.18
2.19
2.0
1.9
—
—
—
0
0
12
48
2.51
2.18
1.2
1.2
—
—
—
0
0
34
203
1.69
2.18
2.3
1.6
—
—
—
0
0
26
144
1.82
2.15
1.2
1.1
—
—
—
0
0
305
2621
1.20
2.15
1.3
1.3
37.41
30.24
iu/ml
0.19
97
855
49
323
1.53
2.13
3.1
4.4
—
—
—
0
0
24
131
1.84
2.08
1.1
1.2
—
—
—
0
0
155
1246
1.27
2.06
1.3
1.2
—
—
—
0
0
26
147
1.78
2.03
1.5
1.3
—
—
—
0
0
83
613
1.37
2.01
1.3
1.2
0.24
1.24
u/ml
—
7
45
101
775
1.32
1.92
2.5
2.2
4932.37
4465.04
u/l
0.06
41
316
157
1278
1.25
1.89
6.4
9.4
96.51
95.79
%
0.88
149
1234
25
144
1.75
1.85
1.5
1.3
2.39
2.88
g/l
0.92
19
98
25
144
1.75
1.85
1.5
1.3
0.25
0.39
g/l
2.20
19
99
25
144
1.75
1.85
1.5
1.3
5.91
6.89
g/l
1.25
19
100
39
253
1.55
1.85
1.7
1.7
—
—
—
0
0
178
1475
1.23
1.83
1.7
1.4
—
—
—
0
0
42
278
1.52
1.83
4.1
3.8
—
—
—
0
0
38
246
1.56
1.82
1.2
1.2
—
—
—
0
0
123
978
1.28
1.81
1.2
1.2
—
—
—
0
0
40
263
1.53
1.79
4.6
3.9
—
—
—
0
0
428
3844
1.15
1.74
4.5
3.8
0.00
0.01
estimate
1.28
145
1344
57
406
1.42
1.74
1.5
2.0
2.67
5.00
iu/l
3.76
12
151
129
1038
1.26
1.73
2.6
2.4
22.38
23.67
au/ml
—
8
84
53
374
1.43
1.70
1.2
1.3
—
—
—
0
0
37
243
1.53
1.68
1.1
1.0
2.26
2.09
u/ml
0.06
22
108
145
1188
1.24
1.67
6.8
9.7
118.73
121.76
g/l
0.92
139
1157
172
1436
1.22
1.66
6.3
8.8
0.48
1.12
mmol/l
1.45
137
1148
137
1667
0.81
1.65
4.5
4.2
31.95
32.32
%
0.15
106
1172
99
777
1.29
1.63
8.4
10.7
94.49
93.96
%
0.36
99
771
11
49
2.25
1.63
2.6
1.5
—
—
—
0
0
76
578
1.33
1.58
1.7
1.6
—
—
—
0
0
171
1436
1.21
1.57
6.3
8.8
4.95
5.09
kpa
1.46
161
1375
117
945
1.26
1.55
1.4
1.3
75.93
40.86
au/ml
—
6
62
59
433
1.38
1.54
2.1
2.5
—
—
—
0
0
8
33
2.43
1.54
3.0
1.4
—
—
—
0
0
416
3761
1.14
1.53
4.6
3.3
988.43
305.11
mg/l
1.13
274
2409
99
786
1.28
1.51
8.3
10.5
1.26
1.37
%
0.75
99
781
38
258
1.48
1.51
1.7
1.7
—
—
—
0
0
98
778
1.28
1.50
8.5
10.7
0.68
0.70
%
0.17
98
773
461
4203
1.13
1.49
4.3
3.2
7.13
7.52
mmol/l
1.11
411
3597
14
72
1.95
1.49
2.4
2.1
2.26
1.95
ug/l
0.21
14
62
170
1436
1.20
1.48
6.3
8.8
12.79
12.42
kpa
0.42
160
1378
39
268
1.47
1.47
1.1
1.1
5.30
9.92
au/ml
—
5
18
19
109
1.75
1.47
1.4
1.1
13.42
12.51
iu/ml
—
6
27
10
45
2.23
1.46
1.1
1.1
—
—
—
0
0
120
980
1.24
1.45
2.9
2.8
123.06
166.48
ng/l
1.65
111
891
108
1327
0.80
1.44
6.8
3.9
—
—
—
0
0
33
220
1.51
1.44
1.3
1.6
—
—
—
0
0
14
73
1.93
1.44
2.4
2.1
4.23
3.06
ug/l
0.41
14
66
35
237
1.49
1.42
1.3
1.4
—
—
—
0
0
10
46
2.18
1.40
1.0
1.0
—
—
—
0
0
435
3967
1.13
1.39
5.2
3.9
11.31
9.24
mg/mmol
0.47
285
2491
13
67
1.95
1.38
3.5
2.9
577.77
951.39
u/ml
0.97
13
67
25
158
1.59
1.37
1.3
1.6
—
—
—
0
0
22
135
1.64
1.36
2.2
2.7
—
—
—
0
0
48
349
1.39
1.36
1.4
1.6
19.27
21.96
e6/l
0.06
37
270
48
349
1.39
1.36
1.4
1.6
206.00
1387.88
e6/l
0.81
38
282
128
1062
1.22
1.35
5.7
4.4
2.57
0.44
%
0.39
35
276
0
37
0.00
1.34
0.0
1.1
—
31.17
—
0
31
0
38
0.00
1.34
0.0
1.3
—
3.70
—
0
30
0
39
0.00
1.33
0.0
1.3
—
54.20
—
0
30
53
394
1.36
1.32
1.5
1.2
—
1094.17
—
0
12
17
98
1.74
1.31
1.5
1.3
—
—
—
0
0
59
447
1.33
1.30
1.1
1.1
2.98
5.22
u/ml
0.33
12
57
9
43
2.10
1.30
4.3
13.5
—
—
—
0
0
37
260
1.43
1.27
1.1
1.1
—
—
—
0
0
17
99
1.72
1.27
1.8
1.2
—
—
—
0
0
84
671
1.26
1.26
7.5
12.6
—
—
—
0
0
42
305
1.39
1.22
1.0
1.1
4.04
1.92
u/ml
0.40
27
155
133
1122
1.20
1.21
5.7
4.3
0.23
0.11
%
0.73
39
336
138
1171
1.19
1.18
5.6
4.3
1.02
0.98
%
0.07
43
386
6
26
2.31
1.18
1.0
1.2
—
—
—
0
0
6
26
2.31
1.18
3.0
2.8
307.50
3403.50
u/l
—
6
26
55
420
1.32
1.17
1.5
1.5
250.10
289.31
ug/g
0.78
30
242
43
316
1.37
1.17
1.2
1.6
—
—
—
0
0
35
248
1.42
1.17
1.3
1.2
2.06
5.25
u/ml
1.54
17
102
17
102
1.67
1.16
1.6
2.2
—
—
—
0
0
25
166
1.51
1.15
1.4
1.9
—
—
—
0
0
21
134
1.57
1.14
1.3
1.2
0.71
1.83
u/ml
0.62
14
71
26
175
1.49
1.13
1.2
1.3
—
—
nmol/l
—
0
0
19
119
1.60
1.11
1.1
1.1
—
—
—
0
0
433
4010
1.11
1.05
3.8
3.1
—
—
—
0
0
304
2771
1.12
1.00
1.8
1.7
—
—
—
0
0
41
310
1.33
0.97
3.3
2.3
71.67
112.64
ug/min
0.59
30
192
46
355
1.30
0.95
1.0
1.1
4.48
2.90
u/ml
0.22
22
182
33
242
1.37
0.95
1.3
1.2
—
—
—
0
0
39
296
1.32
0.91
1.7
1.4
0.35
0.39
nmol/l
0.20
30
241
22
151
1.46
0.90
1.1
1.1
—
—
—
0
0
81
675
1.21
0.89
3.3
3.3
—
—
—
0
0
124
1076
1.16
0.87
5.1
4.1
0.74
0.64
%
0.23
39
338
6
30
2.00
0.87
1.3
1.9
—
—
—
0
0
41
317
1.30
0.85
2.2
1.8
8214.79
14024.39
e6/l
0.81
28
235
13
80
1.63
0.84
2.2
1.7
3.13
2.87
u/field
—
8
61
24
172
1.40
0.81
1.5
1.4
468.84
350.69
pmol/l
0.55
19
151
6
33
1.82
0.79
1.0
1.2
0.01
0.42
u/ml
—
6
33
24
327
0.73
0.78
1.9
2.5
—
—
—
0
0
27
199
1.36
0.78
1.4
1.3
0.24
0.45
nmol/l
—
5
15
38
296
1.29
0.77
3.6
4.2
2.23
2.55
mmol/l
0.38
26
198
6
34
1.77
0.76
1.2
1.3
65.67
50.37
%
—
6
29
19
132
1.44
0.76
3.2
2.8
1.42
1.45
g/24h
0.02
11
68
15
99
1.52
0.75
1.1
1.1
0.11
0.82
u/ml
—
5
29
38
297
1.29
0.75
3.6
4.2
8.66
8.71
kpa
0.07
38
292
38
297
1.29
0.75
3.6
4.3
5.21
5.01
kpa
1.24
38
292
9
53
1.70
0.75
1.3
1.8
—
—
—
0
0
36
459
0.78
0.75
1.3
1.4
—
—
—
0
0
37
469
0.78
0.74
1.4
1.5
—
—
—
0
0
99
858
1.16
0.73
4.1
3.8
5.10
5.18
kpa
0.47
90
828
37
290
1.28
0.72
2.6
2.3
126.54
130.19
g/l
0.30
24
217
74
627
1.19
0.72
1.8
1.8
—
—
—
0
0
36
456
0.79
0.72
1.3
1.4
—
—
—
0
0
49
402
1.23
0.67
1.4
1.2
15.50
2.71
u/ml
—
6
40
13
86
1.52
0.66
1.2
1.0
—
—
—
0
0
66
560
1.19
0.65
4.1
4.2
24.42
24.84
mmol/l
0.70
61
527
10
62
1.62
0.65
1.0
1.1
—
—
—
0
0
14
95
1.48
0.64
1.3
1.3
1.57
1.57
g/l
0.00
14
95
13
87
1.50
0.63
2.1
3.0
—
—
—
0
0
10
63
1.59
0.61
1.7
1.6
—
—
—
0
0
16
113
1.42
0.61
1.6
1.6
22.00
32.16
%
0.65
11
72
16
113
1.42
0.61
1.6
1.5
—
—
—
0
0
70
602
1.17
0.60
1.3
1.3
240.50
237.77
miu/ml
0.02
38
295
522
4987
1.07
0.60
3.5
3.3
27.75
45.54
ng/l
1.27
307
3161
49
408
1.21
0.60
1.5
1.2
3.91
11.77
u/ml
—
8
68
96
849
1.14
0.58
4.2
3.8
7.41
7.40
ph
0.01
13
108
48
401
1.20
0.57
1.4
1.5
80.27
174.50
pmol/l
1.23
48
394
39
319
1.23
0.57
1.4
1.2
—
—
—
0
0
8
54
1.48
0.57
1.0
1.2
—
—
—
0
0
123
1110
1.12
0.54
6.1
3.6
1.23
1.23
mmol/l
0.32
107
962
12
82
1.47
0.54
1.2
1.0
—
—
—
0
0
12
82
1.47
0.54
1.5
1.2
—
—
—
0
0
15
108
1.39
0.53
2.3
2.2
2.00
1.98
u/field
—
6
52
60
517
1.17
0.52
3.0
6.8
1.76
1.60
%
0.40
55
484
25
197
1.27
0.51
1.4
1.3
0.63
0.61
nmol/l
0.10
25
186
15
109
1.38
0.51
1.1
1.1
—
—
—
0
0
135
1232
1.10
0.50
1.5
1.4
—
—
—
0
0
7
48
1.46
0.46
3.0
1.9
—
—
—
0
0
23
182
1.27
0.46
1.4
1.3
—
—
—
0
0
67
590
1.14
0.46
1.1
1.1
—
—
—
0
0
7
49
1.43
0.46
1.6
1.5
150.86
93.15
nmol/24h
—
7
49
59
515
1.15
0.45
3.2
6.8
0.95
0.88
%
0.58
54
484
41
348
1.18
0.44
1.0
1.1
—
—
—
0
0
31
256
1.21
0.44
3.2
3.0
7.00
7.42
mmol/l
0.37
31
250
10
69
1.45
0.44
1.0
1.5
151.02
140.99
nmol/l
—
10
69
32
266
1.21
0.43
1.3
1.3
2.70
2.98
ug/l
0.17
27
243
10
140
0.71
0.43
2.7
2.8
—
—
—
0
0
38
322
1.18
0.42
1.1
1.1
5.06
6.41
u/ml
0.21
21
173
33
276
1.20
0.42
3.1
2.9
1.33
1.52
mmol/l
1.08
33
269
0
15
0.00
0.41
0.0
1.5
—
8.57
—
0
7
0
15
0.00
0.41
0.0
1.2
—
6.49
—
0
9
8
60
1.33
0.40
1.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
27
223
1.21
0.39
1.6
1.3
—
—
—
0
0
88
798
1.11
0.39
6.3
8.0
24.02
24.58
mmol/l
0.84
82
757
5
35
1.43
0.39
1.4
1.1
—
—
—
0
0
10
71
1.41
0.39
1.6
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
9
66
1.37
0.38
1.1
1.4
104.03
168.80
mmol/24h
—
9
66
27
225
1.20
0.37
3.0
2.7
—
—
—
0
0
10
72
1.39
0.37
3.8
1.6
—
38.80
—
0
7
9
70
1.29
0.36
1.4
1.4
—
—
—
0
0
150
1604
0.93
0.36
1.3
1.3
—
—
—
0
0
31
263
1.18
0.36
1.0
1.0
2.87
3.57
u/ml
0.20
18
127
36
310
1.16
0.35
1.0
1.1
0.53
1.41
u/ml
1.09
16
132
6
44
1.36
0.34
1.0
1.1
—
—
—
0
0
166
1763
0.94
0.34
1.5
1.4
—
—
—
0
0
11
82
1.34
0.34
1.1
1.2
—
—
—
0
0
13
100
1.30
0.33
1.6
1.3
—
—
—
0
0
26
219
1.19
0.33
3.6
3.0
0.75
0.83
nmol/l
0.43
20
174
6
46
1.31
0.33
1.2
1.5
—
—
—
0
0
6
86
0.70
0.33
1.0
1.1
—
—
—
0
0
109
1011
1.08
0.32
2.3
2.6
8.15
5.71
e9/l
0.39
91
847
14
110
1.27
0.31
1.6
1.3
91737.50
116236.85
e6/l
—
8
59
7
52
1.35
0.31
1.4
1.5
—
—
—
0
0
396
3830
1.04
0.31
3.7
3.6
—
—
—
0
0
7
96
0.73
0.31
1.7
1.3
85.57
74.64
umol/l
—
7
96
14
173
0.81
0.28
3.2
2.5
—
—
—
0
0
20
167
1.20
0.28
2.1
2.0
31.75
32.31
pg
0.24
20
167
8
62
1.29
0.28
4.3
2.8
—
—
—
0
0
102
952
1.08
0.27
1.5
1.7
—
—
—
0
0
8
65
1.23
0.27
1.1
1.1
125.00
202.87
iu/ml
—
8
65
5
75
0.67
0.25
2.6
2.8
—
—
—
0
0
9
74
1.22
0.25
1.3
1.7
—
—
—
0
0
68
628
1.09
0.24
4.1
4.0
—
—
—
0
0
6
82
0.73
0.24
2.0
2.8
35833.33
40946.93
ug/l
—
6
82
52
475
1.10
0.24
3.0
3.6
0.21
0.27
g/l
0.30
23
199
13
106
1.23
0.23
1.6
1.4
—
—
—
0
0
29
256
1.14
0.23
1.1
1.1
—
—
—
0
0
89
948
0.94
0.22
2.6
2.8
—
—
—
0
0
11
88
1.25
0.22
1.3
1.3
33.84
24.29
umol/l
0.37
11
81
18
153
1.18
0.22
1.3
1.4
—
—
—
0
0
10
124
0.81
0.21
2.9
2.7
58.70
54.76
%
—
10
112
5
42
1.19
0.21
2.2
2.1
—
—
—
0
0
5
42
1.19
0.21
1.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.06
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
4.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
3.7
3.4
—
—
—
0
0
9
115
0.78
0.20
2.0
1.5
—
—
—
0
0
27
302
0.89
0.19
2.3
3.4
15.58
23.75
mg/l
0.95
14
188
6
51
1.18
0.19
2.0
1.7
—
—
—
0
0
293
2850
1.03
0.19
1.7
1.7
20319182.06
39183419.65
pmol/l
0.38
251
2399
7
59
1.19
0.18
1.3
1.2
—
—
—
0
0
7
60
1.17
0.17
2.4
2.5
—
—
—
0
0
185
1788
1.04
0.17
1.6
1.8
—
—
—
0
0
46
426
1.08
0.17
1.1
1.2
—
—
—
0
0
10
82
1.22
0.17
2.0
1.3
182.78
167.70
pmol/l
—
10
82
17
148
1.15
0.17
1.1
1.5
281.33
282.24
mosm/kgh2o
0.05
12
112
8
68
1.18
0.16
2.3
3.0
—
—
—
0
0
442
4342
1.02
0.15
1.5
1.5
—
—
—
0
0
34
369
0.92
0.15
3.0
2.3
—
—
—
0
0
66
697
0.94
0.15
1.5
2.0
—
—
—
0
0
29
265
1.10
0.14
1.9
1.4
34.06
24.58
u/l
0.57
24
218
66
696
0.95
0.14
1.5
1.9
—
—
—
0
0
62
655
0.94
0.14
1.5
2.1
—
—
—
0
0
67
706
0.95
0.14
1.5
2.0
—
—
—
0
0
26
285
0.91
0.14
1.1
1.1
—
—
—
0
0
15
132
1.14
0.13
1.2
1.1
—
—
—
0
0
67
703
0.95
0.13
1.5
2.0
—
—
—
0
0
26
283
0.92
0.12
1.1
1.1
—
—
—
0
0
30
278
1.08
0.12
3.1
2.5
15.39
16.34
%
0.59
17
138
14
124
1.13
0.11
1.6
1.3
2560.13
2028.46
e6/l
—
8
83
34
318
1.07
0.11
3.4
2.3
0.80
0.88
nmol/l
0.35
27
266
33
309
1.07
0.10
1.4
1.2
—
—
—
0
0
19
173
1.10
0.10
1.7
1.2
—
—
—
0
0
12
106
1.13
0.09
16.8
14.3
889.83
839.78
nmol/l
0.14
12
101
18
164
1.10
0.09
1.1
1.1
—
—
—
0
0
23
248
0.93
0.09
2.7
1.9
8.16
5.40
umol/l
0.52
18
179
17
155
1.10
0.09
3.1
2.4
—
—
—
0
0
538
5432
0.99
0.09
2.7
2.6
—
—
—
0
0
5
65
0.77
0.08
1.0
1.2
—
—
—
0
0
13
117
1.11
0.08
1.2
1.3
—
—
—
0
0
7
66
1.06
0.08
2.9
1.5
—
—
—
0
0
85
827
1.03
0.07
4.1
5.9
—
—
—
0
0
8
92
0.87
0.06
1.5
1.2
—
—
—
0
0
21
224
0.94
0.06
1.0
1.0
0.00
0.32
u/ml
—
5
69
13
142
0.91
0.06
4.9
3.7
—
—
—
0
0
44
457
0.96
0.06
4.9
3.9
1.20
1.37
mmol/l
0.92
44
449
22
207
1.06
0.06
1.4
1.7
—
—
—
0
0
54
557
0.97
0.05
1.6
1.9
—
—
—
0
0
28
293
0.95
0.05
4.0
9.9
105.43
105.27
mmol/l
0.08
23
266
28
292
0.96
0.04
4.0
9.9
11.65
11.37
mmol/l
0.20
23
265
22
209
1.05
0.04
1.6
1.5
—
—
—
0
0
44
427
1.03
0.04
1.5
1.3
—
—
—
0
0
28
269
1.04
0.04
2.7
4.0
23.50
31.60
u/ml
0.48
28
260
23
220
1.05
0.03
1.2
1.3
22.09
29.28
u/l
0.27
16
188
51
498
1.02
0.03
6.2
4.5
—
—
—
0
0
41
421
0.97
0.03
3.6
8.1
1.18
1.28
mmol/l
0.34
33
366
12
128
0.94
0.02
1.7
1.4
1.49
1.47
nmol/l
0.02
12
114
48
490
0.98
0.02
1.6
2.7
—
—
—
0
0
20
192
1.04
0.02
2.8
2.9
—
—
—
0
0
11
103
1.07
0.02
1.0
1.1
1.00
1.05
ratio
—
5
46
194
1947
1.00
0.00
1.6
1.7
—
—
—
0
0
10
95
1.05
0.00
1.0
1.1
—
—
—
0
0
12
125
0.96
0.00
1.4
1.1
—
—
—
0
0
24
241
1.00
0.00
1.0
1.0
9.91
5.13
u/ml
0.39
12
102
103
1035
0.99
0.00
1.4
1.4
—
—
—
0
0
16
156
1.03
0.00
1.3
1.6
7.42
7.68
mmol/l
0.19
16
150
17
166
1.02
0.00
1.8
1.8
55.00
58.90
%
—
10
114
17
174
0.98
0.00
2.6
2.1
—
—
—
0
0
128
1276
1.00
0.00
5.6
3.7
—
—
—
0
0
25
248
1.01
0.00
1.6
1.7
—
—
—
0
0
13
132
0.98
0.00
1.0
1.1
—
—
—
0
0
10
103
0.97
0.00
3.9
1.7
3.85
3.85
mg/l
—
10
98
19
193
0.98
0.00
1.5
1.2
—
—
—
0
0
7
73
0.96
0.00
1.4
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
2.86
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
14
140
1.00
-0.00
2.5
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
13.66
—
0
8
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1273.00
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
417.83
—
0
6

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_LOWERLIMB and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_LOWERLIMB 1.071 [0.91, 1.27] 0.422
Birth year 0.999 [0.99, 1.01] 0.838

During the follow-up period (1.1.1998 — 31.12.2019), 287 out of 5208 females with CD2_BENIGN_MELANOCYTIC_LOWERLIMB died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_LOWERLIMB 0.987 [0.82, 1.19] 0.889
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 228 out of 2989 males with CD2_BENIGN_MELANOCYTIC_LOWERLIMB died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_LOWERLIMB.

N-year risk Females Males
1 0.098% 0.19%
5 0.626% 1.261%
10 1.676% 2.956%
15 3.351% 5.426%
20 6.121% 9.002%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_LOWERLIMB – Melanocytic naevi of lower limb, including hip

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data