No definition available.
Melanocytic naevi of lower limb, including hip
EFO MESH Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_LOWERLIMB
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1622 |
4. Check minimum number of eventsNone |
1622 |
5. Include endpointsNone |
1622 |
6. Filter based on genotype QC (FinnGen only) |
1622 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D22
- Name in latin
- Naevus melanocyticus (cutis) coxae
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi of lower limb, including hip
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi of lower limb, including hip
- Melanocytic naevi
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10634 | 6739 | 3862 |
| Only index persons | 9877 | 6347 | 3530 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.19 | 0.11 |
| Only index persons | 0.20 | 0.23 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 39.83 | 41.13 | 37.49 |
| Only index persons | 41.39 | 42.30 | 39.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1622 | 1117 | 505 |
| Unadjusted period prevalence (%) | 0.33 | 0.38 | 0.22 |
| Median age at first event (years) | 51.29 | 48.10 | 58.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1428
- Matched controls
- 14280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
68.8
323.0
622
158
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
4097.7
323.0
1350
48
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.9
218.8
465
607
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
11.2
160.6
325
365
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
9.3
151.1
342
467
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
8.2
93.2
222
313
2167A
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,NAEVUS PIGMENTOSUS]
+∞
85.3
81
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
7.1
84.4
221
357
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.3
70.1
233
505
L57.0
ICD-10 Finland
Actinic keratosis
5.0
64.6
229
530
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
54.0
56.4
67
13
TQW99
NOMESCO Finland
Other minor procedure on skin
6.5
56.0
153
257
R23.8
ICD-10 Finland
Other and unspecified skin changes
3.2
53.9
328
1207
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
8.6
50.1
113
142
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
21.9
49.7
73
35
XQ845
NOMESCO Finland
Dermatoscopy
14.7
48.1
82
59
XQ848
NOMESCO Finland
Dermatological photography
8.1
45.1
105
139
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
52.8
42.9
51
10
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
21.5
42.1
62
30
9733
FHL
Excision of skin change in operating room or anesthesia
14.2
41.9
72
53
S18
ICPC
Laceration/cut
2.2
40.3
642
3914
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
12.6
39.2
71
59
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
52.7
38.7
46
9
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
8.2
38.0
87
112
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
8.3
37.7
86
110
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.5
36.1
135
323
L82
ICD-10 Finland
Seborrhoeic keratosis
2.7
35.3
278
1177
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
10.9
30.6
59
56
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
59.7
30.2
35
6
PJA12
NOMESCO Finland
Sentinel node biopsy
3.3
29.1
157
514
C43.79
ICD-10 Finland
Malignant melanoma of the lower extremity including hip or other unspecified histology
67.4
29.0
33
5
D03.5
ICD-10 Finland
Melanoma in situ of trunk
42.1
26.8
33
8
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
18.3
26.7
41
23
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
14.9
25.3
42
29
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
13.4
24.8
43
33
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
16.9
24.1
38
23
127
Kela drug reimbursment
Transplant complication
7.6
24.1
57
78
ZXC50
NOMESCO Finland
Cryotherapy
5.8
22.8
66
119
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
10.5
22.7
44
43
L04AA06
ATC
mycophenolic acid; systemic
6.4
22.6
60
97
ZZR00
NOMESCO Finland
Flap of skin
6.9
22.3
56
84
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
15.3
22.0
36
24
S82
ICPC
Naevus/mole
2.4
22.0
208
955
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.7
21.9
64
117
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
31.7
21.5
28
9
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
16.5
21.5
34
21
D22
ICD-10 Finland
Melanocytic naevi
3.5
21.4
105
319
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
8.6
21.2
46
55
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
4.8
19.7
66
142
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.4
19.2
98
307
SPAT1153
SPAT
Removal of sutures
1.8
18.5
432
2815
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.8
18.4
62
134
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.1
17.9
57
116
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
27.1
17.8
24
9
ZZA00
NOMESCO Finland
Split skin graft
4.8
17.5
59
128
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
50.6
17.0
20
*
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
64.1
16.8
19
*
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
5.0
16.7
54
112
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.5
16.7
32
31
Z94.0
ICD-10 Finland
Kidney transplant status
7.1
16.5
40
58
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
7.7
16.2
37
49
E0000UV
ATC
NA
1.6
16.1
557
4029
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
16.9
16.1
25
15
ZQZ00
NOMESCO Finland
Treatment of several skin areas
13.7
16.0
27
20
ZXC15
NOMESCO Finland
Use of photodynamic technique
8.6
15.5
33
39
ZXC20
NOMESCO Finland
Use of chemical agents
5.7
15.5
44
79
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
38.5
15.4
19
5
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
8.4
15.3
33
40
C43.7
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of lower limb, including hip
45.5
15.1
18
*
ZXA05
NOMESCO Finland
Left side
1.7
14.2
328
2105
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
7.2
13.8
33
47
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
17.7
13.8
21
12
TQW80
NOMESCO Finland
Local dermatologic skincare
4.2
13.7
52
128
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
6.1
13.5
36
60
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
10.2
13.0
25
25
A11CC03
ATC
alfacalcidol; systemic
4.5
12.7
44
100
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
7.9
12.6
28
36
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
32.3
12.6
16
5
S21
ICPC
Skin texture symptom/complaint
2.0
12.5
175
947
L04AD01
ATC
ciclosporin; systemic
4.4
12.3
44
103
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.4
12.3
44
103
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
14.5
12.3
20
14
B07.9
ICD-10 Finland
Verruca simplex
3.1
12.2
66
218
L04AX01
ATC
azathioprine; systemic
2.7
12.0
82
312
S77
ICPC
Malignant neoplasm of skin
7.6
11.9
27
36
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.5
11.9
41
93
8090/3-C44.7
ICD-O-3
Basal cell carcinoma, NOS, of skin of lower limb and hip
16.6
11.7
18
11
J01DB01
ATC
cefalexin; oral
1.6
11.6
1123
9993
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
11.2
11.5
21
19
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
15.2
11.3
18
12
L04AA01
ATC
[U] ciclosporin; systemic
4.6
11.3
38
84
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
35.3
11.3
14
*
C43
ICD-10 Finland
Malignant melanoma of skin
17.2
11.2
17
10
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
14.0
11.0
18
13
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.0
10.9
29
49
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
10.9
345
2390
ZXA00
NOMESCO Finland
Right side
1.6
10.5
330
2280
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
4.5
10.5
36
82
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
16.2
10.4
16
10
C43.53
ICD-10 Finland
Malignant melanoma of the torso nodular
18.9
10.3
15
8
C43.51
ICD-10 Finland
Malignant melanoma of the trunk originating in lentigo maligna
23.5
10.2
14
6
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
6.1
10.0
26
43
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
9.9
70
274
A12AA04
ATC
calcium carbonate; oral
4.9
9.9
31
64
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
16.8
9.9
15
9
DAB00
NOMESCO Finland
Excision of lesion of auricle
8.2
9.8
21
26
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.6
9.7
27
49
8743/3-C44.7
ICD-O-3
Low cumulative sun damage melanoma of skin of lower limb and hip
55.4
9.7
11
*
D22.0
ICD-10 Finland
Melanocytic naevi of lip
15.1
9.5
15
10
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
12.4
9.4
16
13
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
8.7
9.3
19
22
L91.0
ICD-10 Finland
Hypertrophic scar
4.7
9.2
30
65
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
7.8
9.1
20
26
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.6
9.1
65
257
137
Kela drug reimbursment
Uraemia requiring dialysis
6.3
9.1
23
37
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.4
9.1
43
131
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
9.0
231
1509
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.5
8.9
25
46
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.1
8.8
47
157
QDE15
NOMESCO Finland
Excision of other superficial lesion of skin in lower limb
50.3
8.7
10
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
6.4
8.5
21
33
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.7
8.4
23
41
D06BB10
ATC
imiquimod; topical
2.4
8.3
70
304
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
8.2
306
2186
L04AA05
ATC
[U] tacrolimus; systemic
17.3
8.1
12
7
5AB14
NOMESCO Finland
NA
17.3
8.1
12
7
TK800
NOMESCO Finland
Hemodialysis
3.7
8.0
33
91
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.9
8.0
46
161
S29
ICPC
Skin symptom/complaint other
1.6
7.9
209
1372
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
13.1
7.9
13
10
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
6.1
7.8
20
33
B03XA02
ATC
darbepoetin alfa; parenteral
4.2
7.8
28
68
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
15.1
7.7
12
8
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
45.2
7.7
9
*
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
18.5
7.6
11
6
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
6.7
7.6
18
27
B03XA01
ATC
erythropoietin; parenteral
5.8
7.5
20
35
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
7.2
7.5
17
24
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.4
244
1692
D06BX02
ATC
ingenol mebutate; topical
5.1
7.4
22
44
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.4
494
3941
QDE20
NOMESCO Finland
Excision and repair of scar or web of skin of lower limb
13.4
7.4
12
9
R4110
NOMESCO Finland
Physiotherapy
1.5
7.4
320
2358
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
+∞
7.3
7
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
7.2
78
382
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
15.8
7.2
11
7
QBA10
NOMESCO Finland
Incision of skin of trunk
5.5
7.2
20
37
UJF32
NOMESCO Finland
Coloscopy
1.5
7.2
300
2189
QDE00
NOMESCO Finland
Excision of loose skin or fold of skin from lower limb
30.2
7.1
9
*
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
7.1
232
1606
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
8.8
7.0
14
16
J02AC01
ATC
fluconazole; systemic
1.4
6.9
548
4483
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.9
6.9
18
31
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.6
6.9
22
48
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.8
6.9
27
72
UJH02
NOMESCO Finland
Anoscopy
2.4
6.8
57
246
Z94.4
ICD-10 Finland
Liver transplant status
8.3
6.8
14
17
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
8.3
6.8
14
17
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.8
450
3573
D18.0
ICD-10 Finland
Haemangioma, any site
2.9
6.8
39
136
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
5.7
6.8
18
32
C43.00
ICD-10 Finland
Malignant melanoma of the lip without histology
40.2
6.8
8
*
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
40.2
6.8
8
*
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
16.8
6.7
10
6
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
6.7
87
461
S26
ICPC
Fear of cancer of skin
5.2
6.6
19
37
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
6.5
123
738
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
6.5
75
381
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
70.1
6.4
7
*
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
70.1
6.4
7
*
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
2.9
6.4
35
121
D07XC01
ATC
betamethasone, combinations; topical
1.7
6.3
135
838
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
18.1
6.3
9
5
QXE99
NOMESCO Finland
Other excision or repair of unspecified region of skin
26.8
6.2
8
*
C44.70
ICD-10 Finland
Malignant tumor of the skin of the lower extremity including the hip without histology
26.8
6.2
8
*
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
6.2
121
734
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.0
6.2
18
36
ZXA10
NOMESCO Finland
Bilateral
1.5
6.2
220
1550
D07AB08
ATC
desonide; topical
1.7
6.1
127
784
R50.9
ICD-10 Finland
Fever, unspecified
1.6
6.1
164
1083
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
12.6
6.1
10
8
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.1
126
775
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
6.1
113
677
N18.0
ICD-10 Finland
End-stage renal disease
4.4
6.0
20
46
D01AE16
ATC
amorolfine; topical
1.7
6.0
129
800
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
6.0
460
3721
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
342
2128
1.77
17.94
3.1
2.6
2.2
1.0
e6/l
0.48
210
1187
973
7871
1.59
17.77
11.5
8.9
4.0
4.0
e9/l
0.39
867
6917
495
3512
1.59
15.36
4.4
3.0
0.2
0.4
e6/l
2.29
375
2633
707
5440
1.53
15.23
6.8
4.7
36.7
35.9
g/l
3.50
655
5081
724
5631
1.52
14.65
2.7
2.3
78.2
76.4
nmol/l
1.10
666
5110
788
6293
1.49
13.71
9.0
6.6
1.2
1.2
mmol/l
0.35
678
5339
1170
10139
1.55
13.68
10.2
7.2
75.9
77.4
u/l
0.65
1109
9549
1151
9963
1.53
13.29
5.1
4.0
10.4
11.4
mm/h
2.02
1075
9244
1304
11625
1.62
13.10
20.7
15.6
13.5
13.6
%
0.38
1285
11368
218
1302
1.78
12.86
7.8
4.0
225.4
244.2
u/l
1.39
210
1239
304
1998
1.64
12.61
3.6
2.8
3.3
3.0
e6/l
0.19
172
1065
182
1044
1.84
12.25
11.8
7.5
10.1
8.9
mmol/l
1.40
176
1003
715
5693
1.46
12.10
7.9
5.9
1.2
1.2
mmol/l
0.43
661
5173
67
266
2.58
11.50
10.3
5.6
3786.8
186.1
iu/ml
0.46
12
34
1212
10795
1.49
10.56
4.7
4.1
14.7
14.6
pmol/l
0.22
1128
9940
372
2663
1.52
10.46
3.8
2.4
5.6
6.8
e6/l
0.91
334
2346
241
1581
1.62
9.92
9.7
5.8
1.1
1.0
mmol/l
0.43
231
1468
809
6741
1.40
9.92
4.0
3.5
0.0
0.0
estimate
1.06
131
1243
801
6674
1.40
9.76
5.6
4.7
0.0
0.0
estimate
0.50
136
1274
797
6638
1.39
9.72
4.0
3.5
0.0
0.0
estimate
0.00
132
1256
1468
13728
1.73
9.54
17.9
14.3
139.7
139.6
mmol/l
0.30
1442
13372
1023
8903
1.40
9.52
4.9
4.2
3705.1
2377.8
e6/l
—
9
116
552
4358
1.40
9.06
4.4
3.4
2.4
2.4
mmol/l
0.15
485
3853
284
1979
1.53
8.94
5.0
3.5
0.8
0.8
mmol/l
0.03
262
1852
1468
13769
1.70
8.90
18.3
14.4
3.9
3.9
mmol/l
1.58
1442
13387
564
4485
1.39
8.82
4.6
3.1
28.8
30.9
u/l
1.34
539
4272
431
3276
1.43
8.71
3.7
2.5
3336.8
5260.2
umol/l
0.50
381
2866
156
950
1.71
8.53
6.0
3.7
101.7
80.8
ng/l
1.31
144
835
1370
12670
1.52
8.50
5.6
4.8
1.8
2.0
mu/l
1.03
1288
11749
630
5127
1.37
8.47
2.1
1.9
97.6
96.5
pmol/l
0.25
318
2682
81
401
2.07
8.42
2.4
2.4
9.9
10.4
g/l
0.61
73
346
794
6729
1.35
8.12
8.1
6.0
11.7
11.2
umol/l
0.33
755
6376
312
2273
1.46
7.82
3.8
2.9
2.4
2.4
mmol/l
0.53
271
2011
83
428
1.99
7.74
2.3
2.4
—
—
—
0
0
83
428
1.99
7.74
2.3
2.4
7.0
7.4
g/l
1.17
67
335
83
428
1.99
7.74
2.3
2.4
3.9
3.7
g/l
0.27
67
320
16
32
5.04
7.67
1.0
1.8
1.6
1.9
ug/l
—
7
17
83
432
1.97
7.54
2.9
1.6
1.1
1.2
g/l
3.25
78
406
275
1969
1.48
7.51
3.6
2.3
13.6
13.5
umol/l
0.08
265
1826
13
22
5.95
7.38
5.1
6.5
—
—
—
0
0
28
89
3.18
7.28
2.1
2.7
—
—
—
0
0
1446
13627
1.56
7.20
17.3
12.9
21.1
21.9
mg/l
0.37
1103
10676
1581
15285
2.36
7.20
24.8
18.9
4.5
4.5
e12/l
0.32
1554
14903
1580
15272
2.34
7.18
24.8
19.0
255.8
255.7
e9/l
0.02
1558
14929
315
2334
1.43
7.17
3.8
3.5
529.9
489.0
ng/l
0.04
223
1684
1581
15288
2.35
7.14
24.8
19.0
6.5
6.7
e9/l
1.83
1555
14904
251
1785
1.48
7.07
3.7
2.3
2.3
2.4
g/l
0.95
241
1664
73
372
2.01
7.06
2.8
2.6
0.7
0.9
g/l
0.19
66
333
1581
15293
2.34
7.05
24.9
19.1
134.7
135.0
g/l
0.33
1571
15096
234
1646
1.49
6.96
3.9
2.4
23.6
23.1
%
0.23
215
1414
147
932
1.63
6.91
2.7
2.9
66.3
67.0
g/l
0.48
141
856
77
405
1.95
6.82
2.4
2.4
3.1
3.1
g/l
0.04
67
326
213
1482
1.50
6.67
4.5
2.6
8.4
7.3
umol/l
0.42
191
1277
1513
14453
1.70
6.66
13.3
9.8
24.8
25.8
u/l
1.60
1485
13998
55
260
2.15
6.50
1.9
1.4
108.9
110.5
u/ml
0.04
11
48
78
428
1.86
6.11
1.4
1.4
11.4
10.2
u/l
0.25
64
346
135
865
1.61
6.10
1.7
1.7
—
—
—
0
0
76
414
1.88
6.09
1.2
1.2
—
—
—
0
0
1504
14399
1.61
5.87
19.3
14.5
77.9
73.4
umol/l
3.73
1504
14394
125
797
1.62
5.77
2.0
2.1
11.1
12.3
nmol/l
1.00
114
703
179
1238
1.50
5.77
2.8
2.3
34.7
36.7
u/l
0.29
159
1052
75
417
1.84
5.66
1.2
1.2
—
—
—
0
0
258
1927
1.40
5.53
2.5
2.1
29.4
29.5
s
0.17
250
1864
243
1801
1.41
5.45
2.6
2.3
97.7
114.2
ug/g
0.54
196
1411
184
1296
1.47
5.42
3.4
2.0
369.9
377.3
nmol/l
0.23
173
1194
8
5
16.07
5.41
5.4
3.0
19.4
19.0
mg/l
—
8
5
730
6341
1.28
5.41
3.7
2.8
107.1
104.3
ug/l
0.12
680
5902
17
48
3.57
5.33
1.2
1.2
—
—
—
0
0
1059
9640
1.28
5.30
3.4
3.3
—
—
—
0
0
152
1042
1.51
5.12
3.4
2.8
10.1
10.5
g/l
0.70
140
953
1420
13501
1.42
5.04
5.1
4.5
2.8
2.8
mmol/l
0.67
1343
12540
33
141
2.37
5.01
6.1
4.2
33.2
73.2
u/ml
0.72
11
38
1347
12725
1.35
4.75
4.1
3.7
1.2
1.3
mmol/l
2.16
1266
11790
141
970
1.50
4.68
1.3
1.3
156.5
216.1
u/ml
0.70
133
895
391
3185
1.30
4.68
2.4
2.2
—
—
—
0
0
846
7561
1.25
4.65
5.5
4.7
6.5
6.6
mmol/l
1.10
789
7020
728
6398
1.25
4.64
4.1
3.9
—
—
—
0
0
17
53
3.23
4.62
1.3
2.2
—
—
—
0
0
17
53
3.23
4.62
1.3
2.2
—
—
—
0
0
8
8
10.04
4.52
2.1
1.1
—
—
—
0
0
97
620
1.60
4.48
6.1
4.1
24.0
24.1
mmol/l
0.07
90
565
24
93
2.60
4.48
2.4
2.7
12.9
12.8
%
0.02
15
53
133
913
1.50
4.47
3.8
3.3
4.5
4.5
pmol/l
0.01
122
806
449
3747
1.27
4.42
2.2
2.1
186.3
217.1
u/l
0.35
418
3545
64
370
1.76
4.32
2.9
2.7
—
—
—
0
0
143
1005
1.46
4.29
2.8
2.4
63.6
69.2
ml/min/173m2
0.75
58
396
24
96
2.52
4.22
1.1
1.2
—
—
—
0
0
339
2746
1.30
4.19
1.5
1.5
—
—
—
0
0
121
827
1.50
4.17
1.3
1.4
23.0
27.3
iu/l
0.81
102
703
81
507
1.63
4.10
2.7
2.0
1.2
1.5
g/l
1.70
74
444
33
155
2.15
4.07
3.4
1.6
60.5
26.8
iu/ml
—
6
9
69
415
1.69
4.07
3.5
1.6
0.2
0.2
g/l
1.89
64
391
182
1356
1.39
3.96
1.8
1.7
—
—
—
0
0
248
1945
1.32
3.87
1.9
1.8
—
—
—
0
0
394
3287
1.26
3.82
2.5
2.1
2.8
2.9
mg/l
0.70
343
2807
153
1114
1.41
3.81
5.7
3.7
1.5
1.9
mmol/l
0.79
135
896
1391
13296
1.32
3.80
4.6
4.1
4.7
4.7
mmol/l
0.37
1322
12423
40
208
1.95
3.79
1.1
1.1
—
—
—
0
0
6
5
12.04
3.76
1.8
1.4
6.7
4.6
mg/l
—
6
5
351
2894
1.27
3.75
3.9
3.8
1.0
1.0
kg/l
0.07
46
421
24
102
2.37
3.75
3.2
2.5
—
—
—
0
0
1384
13228
1.32
3.72
4.5
4.1
1.5
1.5
mmol/l
1.38
1315
12295
101
682
1.51
3.71
1.6
1.6
—
—
—
0
0
1335
12701
1.29
3.70
15.8
11.5
82.5
84.8
ml/min/173m2
2.95
1095
10381
59
350
1.71
3.68
1.6
1.6
—
—
—
0
0
9
16
5.65
3.66
3.2
1.6
—
—
—
0
0
22
92
2.41
3.56
1.1
1.3
—
—
—
0
0
392
3295
1.25
3.53
1.4
1.3
1.1
1.5
u/ml
0.44
111
869
586
5141
1.22
3.53
4.1
3.6
—
—
—
0
0
417
3531
1.24
3.52
1.7
1.6
1.4
1.4
mmol/l
0.04
377
3016
1344
12817
1.28
3.52
18.9
13.8
40.0
39.8
%
0.62
1051
9692
152
1123
1.39
3.49
5.4
3.7
5.9
5.8
kpa
0.36
146
1088
173
1308
1.36
3.45
3.5
2.8
1.6
1.8
%
2.85
163
1172
472
4058
1.23
3.45
3.7
2.5
56.5
56.3
u/l
0.04
435
3751
180
1372
1.35
3.41
1.9
1.8
—
—
—
0
0
194
1497
1.34
3.39
6.3
6.4
—
—
—
0
0
74
477
1.58
3.37
1.8
1.7
—
—
—
0
0
50
291
1.74
3.36
1.5
1.3
293.0
244.6
u/ml
0.41
37
172
279
2266
1.28
3.35
4.7
4.2
25.1
20.9
%
3.21
130
1055
1352
12927
1.28
3.30
4.6
4.2
5.8
5.8
mmol/l
0.80
1269
11871
147
1092
1.38
3.28
1.3
1.2
104.9
140.5
iu/ml
0.74
54
422
52
310
1.70
3.23
1.5
1.2
—
—
—
0
0
8
15
5.35
3.19
2.1
1.3
192.1
79.1
ng/l
—
8
15
67
430
1.58
3.13
1.4
1.6
0.7
0.2
iu/ml
0.33
15
79
18
73
2.48
3.13
1.6
1.1
100.1
79.3
u/l
0.50
18
65
17
67
2.55
3.13
1.2
1.1
1583.8
1638.6
miu/ml
0.06
17
67
160
1215
1.35
3.12
3.8
4.3
3.3
22.4
ug/l
2.06
128
989
14
50
2.82
3.09
3.4
2.0
68.9
70.9
ug/l
0.02
14
50
43
247
1.76
3.05
2.2
1.4
—
—
—
0
0
53
324
1.66
3.02
1.3
1.3
—
—
—
0
0
33
175
1.90
3.01
1.2
1.3
—
—
—
0
0
136
1014
1.37
2.99
1.6
1.8
—
—
—
0
0
294
2438
1.25
2.96
1.3
1.3
40.0
30.2
iu/ml
0.24
89
767
63
406
1.57
2.91
1.3
1.3
—
—
—
0
0
1267
12079
1.22
2.85
5.7
5.3
38.6
39.2
mmol/mol
1.48
1189
11272
280
2322
1.25
2.82
1.3
1.3
10.0
11.2
u/ml
0.11
96
925
125
930
1.37
2.80
2.2
2.3
6.5
7.0
ug/l
0.12
107
823
373
3195
1.22
2.76
3.1
2.9
1406.1
1143.0
ng/l
0.51
311
2671
81
559
1.47
2.75
1.3
1.2
0.2
1.3
u/ml
—
7
42
36
203
1.79
2.74
1.2
1.1
—
—
—
0
0
264
2184
1.25
2.71
1.7
1.7
1192.0
1187.2
nmol/l
0.03
201
1656
112
823
1.39
2.71
1.4
1.4
—
—
—
0
0
85
597
1.45
2.65
1.8
2.0
39.9
39.6
u/l
0.05
72
536
41
243
1.71
2.65
1.3
1.4
—
—
—
0
0
41
243
1.71
2.65
1.3
1.4
—
—
—
0
0
333
2835
1.22
2.62
5.2
4.9
2.0
2.4
ug/l
1.00
305
2547
58
377
1.56
2.61
1.6
2.1
11.4
11.6
mg/l
0.08
53
349
18
80
2.26
2.61
1.2
1.3
—
—
—
0
0
60
398
1.53
2.49
1.2
1.1
—
—
—
0
0
11
39
2.83
2.47
1.2
1.2
—
—
—
0
0
13
51
2.56
2.44
1.2
1.2
—
—
—
0
0
136
1050
1.32
2.42
6.4
7.4
1.2
1.4
mmol/l
1.79
130
1004
23
117
1.98
2.41
6.1
3.8
—
—
—
0
0
204
1663
1.26
2.39
3.4
3.0
0.7
0.7
ug/l
0.44
149
1076
44
274
1.62
2.39
4.4
3.8
59.1
57.3
%
0.56
44
274
21
104
2.03
2.36
1.9
1.2
—
—
—
0
0
161
1277
1.29
2.36
1.8
1.9
—
—
—
0
0
64
436
1.49
2.36
4.3
3.5
111.1
987.3
u/ml
1.29
50
375
51
331
1.56
2.34
4.0
3.8
71.4
66.6
mg/l
0.04
38
265
51
331
1.56
2.34
4.0
3.8
31.6
40.6
mg/l
0.37
38
266
10
35
2.87
2.30
1.2
1.1
—
—
—
0
0
16
72
2.23
2.28
1.1
1.1
—
—
—
0
0
79
565
1.42
2.27
1.7
1.4
—
—
—
0
0
12
47
2.56
2.27
2.5
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
52
342
1.54
2.26
3.2
3.3
0.3
0.4
u/ml
2.15
28
183
21
106
1.99
2.26
2.9
1.6
—
—
—
0
0
981
9233
1.16
2.20
3.7
3.0
41.4
43.1
u/l
0.35
927
8704
10
36
2.79
2.20
1.2
1.1
—
—
—
0
0
42
265
1.60
2.19
4.0
3.6
3.9
4.1
e9/l
0.28
42
265
120
935
1.31
2.04
4.5
3.1
4.7
4.7
kpa
0.19
115
905
36
223
1.63
2.03
2.1
1.6
—
—
—
0
0
162
1314
1.26
2.01
5.8
8.6
0.5
1.1
mmol/l
1.19
126
1036
10
38
2.64
2.01
1.2
1.2
—
—
—
0
0
20
104
1.93
2.00
2.0
1.6
1.0
1.0
g/l
0.02
20
104
355
3114
1.18
2.00
2.3
1.7
0.9
1.1
mg/l
1.01
258
2368
334
2916
1.18
1.99
1.7
1.6
—
—
—
0
0
331
2890
1.18
1.97
1.5
1.5
22.0
20.7
nmol/l
0.78
283
2474
123
967
1.29
1.96
2.6
2.4
24.0
19.3
au/ml
—
7
58
96
729
1.34
1.96
1.6
1.5
—
—
—
0
0
34
210
1.63
1.95
1.5
1.2
—
—
—
0
0
94
713
1.34
1.93
2.3
2.2
5437.3
4730.9
u/l
0.08
37
294
8
27
2.97
1.93
2.5
1.1
—
—
—
0
0
8
27
2.97
1.93
2.6
1.1
75.9
101.3
%
—
8
27
6
16
3.76
1.93
1.3
1.5
—
—
—
0
0
9
33
2.74
1.93
1.2
1.2
—
—
—
0
0
35
219
1.61
1.92
1.1
1.0
2.4
1.8
u/ml
0.23
20
97
161
1316
1.25
1.88
5.8
8.6
4.9
5.1
kpa
1.54
152
1260
112
877
1.30
1.85
1.4
1.3
88.7
35.7
au/ml
—
5
48
58
410
1.43
1.83
1.1
1.1
3.2
5.2
u/ml
0.27
11
54
92
705
1.32
1.79
7.6
10.3
94.3
93.9
%
0.25
92
700
160
1316
1.24
1.78
5.8
8.6
12.7
12.4
kpa
0.26
151
1263
399
3565
1.16
1.77
4.5
3.8
0.0
0.0
estimate
1.28
133
1247
134
1082
1.26
1.75
6.2
9.5
118.5
121.8
g/l
0.95
129
1045
7
24
2.92
1.72
1.3
1.2
—
—
—
0
0
54
383
1.42
1.69
1.5
2.0
2.6
5.1
iu/l
3.96
11
142
433
3907
1.15
1.67
4.3
3.3
7.1
7.6
mmol/l
1.17
381
3318
40
268
1.50
1.67
1.4
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
15
76
1.98
1.64
1.1
1.2
—
—
—
0
0
38
255
1.50
1.58
1.1
1.1
5.3
10.4
au/ml
—
5
17
6
20
3.01
1.58
1.3
1.1
—
—
—
0
0
77
590
1.32
1.53
1.5
1.4
—
—
—
0
0
27
169
1.61
1.52
1.1
1.1
—
—
—
0
0
28
177
1.59
1.52
1.9
1.5
—
—
—
0
0
77
591
1.32
1.52
7.3
10.9
24.1
24.3
mmol/l
0.24
71
558
6
21
2.86
1.50
1.3
1.1
—
—
—
0
0
18
101
1.79
1.49
1.4
1.1
13.4
12.7
iu/ml
—
6
26
9
38
2.38
1.45
1.2
1.1
—
—
—
0
0
168
1422
1.20
1.44
30.9
22.2
1.6
1.3
inr
1.00
25
205
23
141
1.64
1.42
1.8
1.5
—
—
—
0
0
24
149
1.62
1.41
2.0
1.7
—
—
—
0
0
24
150
1.61
1.38
1.1
1.1
—
—
—
0
0
12
60
2.01
1.38
3.6
2.8
570.3
938.3
u/ml
0.83
12
60
6
23
2.61
1.37
1.3
1.3
—
—
—
0
0
49
358
1.38
1.35
1.4
1.2
—
—
—
0
0
17
97
1.76
1.35
1.2
1.2
—
—
—
0
0
45
324
1.40
1.35
1.4
1.6
20.6
12.3
e6/l
0.22
34
250
45
324
1.40
1.35
1.4
1.7
223.6
722.4
e6/l
0.58
35
259
14
75
1.87
1.34
2.1
1.7
2.8
2.7
u/field
—
9
56
110
900
1.24
1.33
2.9
2.8
127.2
166.2
ng/l
1.28
104
816
16
90
1.79
1.33
1.9
1.5
2.4
8.7
u/l
—
8
42
404
3685
1.13
1.31
5.3
4.0
11.0
9.3
mg/mmol
0.35
263
2308
16
92
1.75
1.25
1.3
1.2
—
—
—
0
0
61
468
1.32
1.25
1.5
1.3
—
—
—
0
0
6
25
2.41
1.24
3.0
2.8
307.5
3486.9
u/l
—
6
25
16
93
1.73
1.21
1.3
1.2
—
—
—
0
0
52
393
1.33
1.19
1.6
1.5
247.5
291.7
ug/g
0.84
28
225
28
190
1.48
1.16
1.9
1.6
—
—
—
0
0
66
519
1.28
1.14
4.2
4.2
24.4
24.9
mmol/l
0.81
61
490
20
126
1.59
1.14
1.8
1.5
—
—
—
0
0
33
233
1.42
1.13
1.4
1.2
2.1
5.5
u/ml
1.46
15
93
43
572
0.74
1.12
2.2
1.9
—
—
—
0
0
37
268
1.39
1.11
1.6
1.7
—
—
—
0
0
7
31
2.26
1.10
1.3
1.1
46.4
37.5
u/ml
—
7
31
20
128
1.57
1.08
1.3
1.8
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
7
32
2.19
1.08
1.0
1.2
—
72.6
—
0
8
40
296
1.36
1.06
2.2
1.8
7419.0
14044.5
e6/l
0.94
27
222
18
113
1.60
1.05
1.1
1.1
—
—
—
0
0
18
113
1.60
1.05
1.1
1.1
—
—
—
0
0
39
288
1.36
1.05
3.5
2.4
69.4
91.9
ug/min
0.30
28
177
7
33
2.13
1.05
2.0
1.8
—
—
—
0
0
96
798
1.22
1.05
4.1
3.8
5.1
5.2
kpa
0.30
86
757
12
67
1.80
1.04
1.1
1.3
—
75.0
—
0
12
32
229
1.41
1.04
1.9
1.4
—
—
—
0
0
22
146
1.51
1.03
1.4
1.3
—
—
—
0
0
18
114
1.59
1.02
1.1
1.1
—
—
—
0
0
18
114
1.59
1.02
1.1
1.1
—
—
—
0
0
18
114
1.59
1.02
1.1
1.1
—
—
—
0
0
195
1728
1.15
1.01
1.7
1.8
1.4
1.4
%
1.41
171
1538
41
310
1.33
0.97
2.1
1.6
—
—
—
0
0
43
330
1.31
0.93
1.0
1.1
5.1
1.7
u/ml
0.39
16
130
37
278
1.34
0.92
1.7
1.4
0.4
0.4
nmol/l
0.14
28
227
137
1566
0.86
0.90
4.5
4.2
31.9
32.4
%
0.21
103
1082
41
314
1.31
0.90
2.0
1.6
—
—
—
0
0
26
185
1.41
0.89
3.4
2.3
41.7
26.5
u/ml
0.14
26
170
492
4624
1.09
0.89
3.6
3.3
28.6
43.5
ng/l
0.91
288
2922
18
120
1.51
0.85
1.2
1.1
—
—
—
0
0
8
45
1.78
0.84
1.5
1.3
—
—
—
0
0
42
328
1.29
0.82
1.7
1.5
—
—
—
0
0
90
765
1.19
0.82
4.2
3.8
1.3
1.7
mmol/l
0.50
67
575
37
284
1.31
0.82
1.6
1.4
—
—
—
0
0
46
368
1.26
0.76
1.5
1.2
15.5
2.8
u/ml
—
6
38
9
54
1.67
0.74
1.4
1.1
112.7
112.3
%
—
9
44
16
108
1.49
0.73
1.6
1.4
—
—
—
0
0
5
25
2.00
0.72
1.0
1.4
—
—
—
0
0
47
380
1.24
0.72
1.4
1.4
81.2
167.7
pmol/l
1.03
47
374
21
151
1.40
0.71
1.3
1.4
477.7
334.4
pmol/l
0.54
15
114
11
69
1.60
0.68
1.2
1.2
—
—
—
0
0
46
374
1.24
0.68
1.5
1.2
3.9
12.3
u/ml
—
8
63
18
127
1.42
0.68
1.1
1.0
—
—
—
0
0
14
94
1.49
0.66
1.6
1.3
91737.5
108208.1
e6/l
—
8
50
31
241
1.29
0.66
1.3
1.2
7.1
3.6
u/ml
—
8
72
84
729
1.16
0.64
6.5
8.1
24.1
24.7
mmol/l
0.87
78
681
57
479
1.20
0.63
1.7
1.9
—
—
—
0
0
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
52
434
1.20
0.62
1.5
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
2.1
—
—
—
0
0
30
236
1.28
0.60
1.6
1.6
—
—
—
0
0
10
64
1.57
0.58
1.6
1.4
11.0
13.8
u/l
—
10
58
0
23
0.00
0.58
0.0
4.3
—
1.4
—
0
16
14
99
1.42
0.54
1.3
1.1
—
—
—
0
0
26
206
1.27
0.51
1.2
1.2
—
—
—
0
0
45
529
0.85
0.49
1.4
1.4
—
—
—
0
0
7
45
1.56
0.49
2.4
1.6
—
—
—
0
0
7
45
1.56
0.49
2.4
1.6
—
—
—
0
0
65
568
1.15
0.48
1.3
1.3
249.5
234.6
miu/ml
0.13
36
283
45
528
0.85
0.48
1.4
1.4
—
—
—
0
0
7
46
1.52
0.48
2.4
1.6
—
—
—
0
0
45
527
0.85
0.47
1.4
1.4
—
—
—
0
0
7
47
1.49
0.47
1.0
1.3
—
—
—
0
0
49
569
0.86
0.47
1.4
1.5
—
—
—
0
0
45
526
0.85
0.46
1.4
1.4
—
—
—
0
0
33
273
1.21
0.46
2.4
2.3
129.9
129.9
g/l
0.00
20
207
73
647
1.13
0.45
1.5
1.4
—
—
—
0
0
11
77
1.43
0.45
1.3
1.0
—
—
—
0
0
14
103
1.36
0.45
2.2
2.2
2.0
2.1
u/field
—
6
47
22
174
1.27
0.45
1.4
1.3
0.6
0.6
nmol/l
0.10
22
164
57
498
1.15
0.44
4.8
3.4
51.5
48.2
%
0.42
57
492
88
792
1.12
0.44
1.0
1.0
—
—
—
0
0
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
6
95
0.63
0.42
1.2
1.3
—
—
—
0
0
20
158
1.27
0.42
1.3
1.1
—
—
—
0
0
8
58
1.38
0.41
2.3
1.5
—
—
—
0
0
8
58
1.38
0.41
2.3
1.5
—
—
—
0
0
8
58
1.38
0.41
2.3
1.5
—
—
—
0
0
8
58
1.38
0.41
2.3
1.5
—
—
—
0
0
28
231
1.22
0.41
1.1
1.1
—
—
—
0
0
14
105
1.34
0.41
2.2
1.4
—
—
—
0
0
14
105
1.34
0.41
2.2
1.4
—
—
—
0
0
14
105
1.34
0.41
2.2
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.2
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
25
205
1.22
0.39
3.6
3.0
0.8
0.8
nmol/l
0.33
19
162
16
124
1.29
0.38
1.4
1.3
1.1
0.8
u/ml
—
9
50
5
37
1.35
0.37
1.2
1.0
—
—
—
0
0
200
1888
1.07
0.36
2.0
2.1
—
—
—
0
0
28
235
1.19
0.36
1.2
1.1
—
—
—
0
0
6
44
1.36
0.34
1.0
2.2
—
88522.6
—
0
5
6
87
0.69
0.33
4.2
1.9
—
—
—
0
0
11
83
1.33
0.32
1.1
1.1
—
—
—
0
0
277
2655
1.05
0.31
1.7
1.7
21519447.9
33841073.1
pmol/l
0.22
237
2234
13
102
1.28
0.30
1.2
1.1
0.9
1.1
u/l
—
5
49
220
2100
1.06
0.30
2.2
2.2
—
—
—
0
0
7
56
1.25
0.29
1.3
1.0
—
—
—
0
0
8
107
0.75
0.29
1.0
2.1
—
—
—
0
0
34
298
1.14
0.28
2.6
2.8
24.9
25.0
mmol/l
0.05
25
268
8
62
1.29
0.28
2.3
2.5
—
—
—
0
0
8
64
1.25
0.27
1.1
2.0
—
—
—
0
0
50
452
1.11
0.27
3.0
1.9
—
—
—
0
0
24
276
0.87
0.24
2.3
3.4
11.9
24.3
mg/l
3.05
13
172
28
246
1.14
0.23
1.0
1.0
4.1
3.8
u/ml
0.04
11
93
14
115
1.22
0.23
1.3
1.5
—
—
—
0
0
24
209
1.15
0.23
1.3
1.4
6.2
7.4
mmol/l
1.07
16
146
5
39
1.28
0.23
1.0
1.3
—
—
—
0
0
19
162
1.17
0.23
1.7
1.4
—
—
—
0
0
5
40
1.25
0.22
5.0
4.5
—
—
—
0
0
28
248
1.13
0.21
2.0
1.4
35.2
24.2
u/l
0.67
23
209
0
11
0.00
0.21
0.0
6.9
—
—
—
0
0
8
102
0.78
0.21
1.3
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
40
439
0.91
0.21
1.6
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
18
155
1.16
0.20
1.8
1.8
55.0
57.9
%
—
10
108
6
51
1.18
0.19
1.3
1.3
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
—
—
—
0
0
6
52
1.15
0.19
1.0
1.2
—
—
—
0
0
28
251
1.12
0.18
1.3
1.3
2.9
2.9
ug/l
0.03
23
229
18
157
1.15
0.17
1.5
2.3
30.0
27.7
mg/l
—
6
40
7
62
1.13
0.17
1.1
1.1
110.9
208.0
iu/ml
—
7
62
7
63
1.11
0.17
1.3
1.3
—
—
—
0
0
8
70
1.14
0.16
1.3
1.5
—
—
—
0
0
6
78
0.77
0.15
1.7
2.1
—
—
—
0
0
18
159
1.13
0.15
1.8
1.4
—
—
—
0
0
18
159
1.13
0.15
1.8
1.4
—
—
—
0
0
18
159
1.13
0.15
1.8
1.4
—
—
—
0
0
29
265
1.10
0.14
1.4
1.5
—
—
—
0
0
95
991
0.96
0.14
1.5
1.5
—
—
—
0
0
18
160
1.13
0.14
1.8
1.4
—
—
—
0
0
132
1279
1.03
0.12
3.6
3.1
—
—
—
0
0
18
162
1.11
0.12
1.8
1.4
—
—
—
0
0
13
114
1.14
0.11
2.3
2.5
—
—
—
0
0
27
250
1.08
0.11
3.5
2.9
1.4
1.5
mmol/l
0.52
27
244
105
1017
1.03
0.10
6.4
3.5
1.2
1.2
mmol/l
0.28
93
884
25
232
1.08
0.09
3.7
3.0
6.8
7.5
mmol/l
0.53
25
227
19
174
1.09
0.09
1.4
1.4
—
—
—
0
0
22
237
0.93
0.09
2.6
1.9
7.6
5.4
umol/l
0.37
17
170
15
165
0.91
0.09
1.1
1.1
—
—
—
0
0
7
64
1.09
0.08
1.3
1.3
—
—
—
0
0
7
84
0.83
0.07
1.3
1.5
—
—
—
0
0
9
100
0.90
0.06
2.4
1.5
—
—
—
0
0
10
111
0.90
0.06
1.8
1.6
—
—
—
0
0
19
202
0.94
0.05
1.2
1.2
26.2
28.1
u/l
0.05
12
174
62
604
1.03
0.05
1.5
1.7
3.0
4.2
mg/l
0.52
37
422
141
1390
1.02
0.04
1.8
1.6
—
—
—
0
0
46
474
0.97
0.04
1.6
1.5
—
—
—
0
0
43
417
1.03
0.04
5.0
3.9
1.2
1.4
mmol/l
0.89
43
410
17
160
1.06
0.04
2.4
2.0
31.5
32.4
pg
0.36
17
160
25
241
1.04
0.02
1.3
1.2
—
—
—
0
0
30
291
1.03
0.02
3.1
2.2
0.8
0.9
nmol/l
0.40
23
242
38
371
1.02
0.02
1.4
1.5
—
—
—
0
0
21
202
1.04
0.02
1.5
1.4
—
—
—
0
0
11
103
1.07
0.02
17.4
13.9
895.3
830.2
nmol/l
0.17
11
98
11
116
0.95
0.00
1.7
1.4
1.5
1.4
nmol/l
0.07
11
103
26
254
1.02
0.00
2.8
4.0
24.3
32.4
u/ml
0.44
26
246
10
98
1.02
0.00
1.0
1.5
—
—
—
0
0
52
524
0.99
0.00
2.1
1.7
—
—
—
0
0
14
142
0.99
0.00
1.1
1.5
8.5
12.5
mmol/l
—
6
29
26
262
0.99
0.00
2.9
2.4
15.7
16.3
%
0.28
14
131
12
119
1.01
0.00
1.2
1.1
—
—
—
0
0
11
105
1.05
0.00
1.8
1.1
—
43.2
—
0
5
6
60
1.00
0.00
5.0
3.2
—
—
—
0
0
9
93
0.97
0.00
2.9
1.7
3.1
3.8
mg/l
—
9
88
0
6
0.00
0.00
0.0
1.5
—
2.5
—
0
6
0
9
0.00
0.00
0.0
7.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.3
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_LOWERLIMB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_LOWERLIMB | 1.071 [0.91, 1.27] | 0.422 |
| Birth year | 0.999 [0.99, 1.01] | 0.838 |
During the follow-up period (1.1.1998 — 31.12.2019), 287 out of 5208 females with CD2_BENIGN_MELANOCYTIC_LOWERLIMB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_LOWERLIMB | 0.987 [0.82, 1.19] | 0.889 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 228 out of 2989 males with CD2_BENIGN_MELANOCYTIC_LOWERLIMB died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_LOWERLIMB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.19% |
| 5 | 0.626% | 1.261% |
| 10 | 1.676% | 2.956% |
| 15 | 3.351% | 5.426% |
| 20 | 6.121% | 9.002% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_LOWERLIMB – Melanocytic naevi of lower limb, including hip
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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