No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
185 |
4. Check minimum number of eventsNone |
185 |
5. Include endpointsNone |
185 |
6. Filter based on genotype QC (FinnGen only) |
176 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other/unspecified mastoiditis and related conditions
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1654 | 727 | 908 |
| Only index persons | 1276 | 608 | 668 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 37.17 | 38.88 | 35.47 |
| Only index persons | 33.83 | 36.42 | 31.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 176 | 84 | 92 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.04 |
| Median age at first event (years) | 36.50 | 34.53 | 38.30 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 185
- Matched controls
- 1850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
105.6
91
*
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
77.7
69
*
UDC00
NOMESCO Finland
Ear microscopy
12.3
49.5
58
66
H66.0
ICD-10 Finland
Acute suppurative otitis media
15.1
49.5
49
43
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
36.7
34
*
DC1AD
NOMESCO Finland
Temporalbone CT
342.9
29.7
29
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
248.1
22.1
22
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
20.2
19
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
+∞
20.2
19
*
DFF00
NOMESCO Finland
Pure tone audiometry
5.6
18.8
41
89
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
49.6
18.7
22
5
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
18.0
17
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
6.2
17.0
32
60
H02AB04
ATC
methylprednisolone; systemic
4.5
16.5
50
142
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.3
15.7
49
142
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.9
15.1
58
195
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
14.8
14
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
162.3
14.7
15
*
H70.8
ICD-10 Finland
Other mastoiditis and related conditions
+∞
13.7
13
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
13.7
13
*
38399
ICD-8 Finland
Mastoiditis without mention of otitis media, Unspecified
+∞
12.6
12
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
40.5
12.4
15
*
H66.9
ICD-10 Finland
Otitis media, unspecified
9.3
11.7
24
29
H65.2
ICD-10 Finland
Chronic serous otitis media
+∞
11.6
11
*
H92.0
ICD-10 Finland
Otalgia
5.6
10.6
21
41
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
10.5
10
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
+∞
10.5
10
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.9
10.5
73
343
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.7
10.1
113
673
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
105.2
9.5
10
*
H02AB06
ATC
prednisolone; systemic
2.6
9.4
108
643
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
7.5
9.1
21
31
H65.0
ICD-10 Finland
Acute serous otitis media
38.8
9.1
11
*
ZXE00
NOMESCO Finland
One hour or less
2.6
8.9
87
477
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
94.2
8.5
9
*
4151
FHL
Reoperation for chronic otitis media
+∞
8.4
8
*
S02CA02
ATC
flumetasone and antiinfectives; otic
4.2
8.3
23
60
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
35.0
8.2
10
*
H61.2
ICD-10 Finland
Impacted cerumen
4.3
8.1
22
56
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
11.5
7.9
14
13
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
19.4
7.7
11
6
H60.1
ICD-10 Finland
Cellulitis of external ear
19.4
7.7
11
6
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
+∞
7.3
7
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
7.3
7
*
H60.3
ICD-10 Finland
Other infective otitis externa
8.5
7.3
15
19
UJF32
NOMESCO Finland
Coloscopy
2.5
7.1
58
287
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.1
7.0
20
53
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
6.9
78
445
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
6.7
27
91
DCD00
NOMESCO Finland
Myringoplasty
+∞
6.3
6
*
N03AX16
ATC
[U] pregabalin
2.4
6.2
51
252
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
6.2
73
421
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
6.2
56
289
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.8
6.1
19
54
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
77
4.64
11.95
13.4
5.8
24.46
25.23
mmol/l
0.56
31
77
41
136
3.59
10.62
5.9
3.5
—
—
—
0
0
21
33
7.04
8.79
3.2
3.2
4.79
5.11
kpa
0.85
21
33
18
38
5.14
8.31
1.6
1.4
—
—
—
0
0
32
108
3.37
7.97
4.4
3.5
1.22
1.22
mmol/l
0.34
26
96
18
48
4.05
6.25
3.1
2.6
—
—
—
0
0
16
31
5.55
5.86
2.2
2.6
18.30
15.88
%
—
7
13
65
365
2.20
5.80
4.4
4.1
0.00
0.00
estimate
-0.00
28
126
16
33
5.21
5.58
1.3
1.4
—
—
—
0
0
54
289
2.23
5.37
1.6
1.8
2.01
1.26
mg/l
0.28
39
225
101
690
2.02
5.21
4.0
3.8
0.00
0.00
estimate
-0.00
32
142
136
1044
2.14
4.99
5.5
4.1
14.18
12.02
mm/h
0.74
121
957
12
21
6.03
4.84
1.9
2.0
91.58
91.15
%
0.11
12
21
83
540
1.97
4.82
4.0
4.0
—
—
—
0
0
100
694
1.96
4.80
5.1
5.2
0.00
0.00
estimate
-0.00
31
131
66
401
2.00
4.62
4.0
2.8
0.35
0.29
e6/l
0.18
49
301
100
703
1.92
4.54
4.0
3.9
0.00
0.00
estimate
-0.00
32
123
12
24
5.27
4.40
3.5
2.7
4.06
4.78
e9/l
0.49
12
24
78
512
1.91
4.30
4.1
2.9
—
—
—
0
0
85
574
1.89
4.29
4.9
3.8
27.79
42.56
ng/l
0.85
63
411
12
25
5.06
4.26
5.4
3.4
59.92
56.64
%
0.29
12
25
42
225
2.12
4.08
2.0
1.6
—
—
—
0
0
51
297
1.99
3.95
1.7
1.7
388.17
456.26
pmol/l
1.83
36
255
9
16
5.85
3.70
1.6
1.4
—
—
—
0
0
8
13
6.38
3.54
1.5
1.3
—
—
—
0
0
46
268
1.95
3.53
2.3
3.1
2.47
2.45
mmol/l
0.40
40
235
86
616
1.74
3.36
3.3
2.6
144.04
111.47
ug/l
0.71
70
564
10
27
3.85
2.92
1.4
1.3
—
—
—
0
0
9
22
4.24
2.92
1.4
1.3
—
—
—
0
0
6
9
6.84
2.89
1.2
1.1
—
—
—
0
0
52
335
1.77
2.87
1.8
1.6
17.34
22.02
nmol/l
1.85
41
279
11
33
3.48
2.86
1.5
1.4
—
—
—
0
0
55
363
1.73
2.79
2.6
2.0
3.09
2.97
mg/l
0.16
41
316
11
35
3.28
2.69
1.5
1.3
—
—
—
0
0
8
20
4.13
2.60
1.4
1.5
—
—
—
0
0
6
11
5.59
2.56
1.2
1.2
—
—
—
0
0
89
681
1.59
2.49
19.2
14.3
1.20
1.33
inr
1.09
49
203
34
201
1.85
2.47
2.5
2.1
22.37
24.28
%
0.35
29
177
60
419
1.64
2.43
2.2
2.1
126.71
228.72
u/l
1.37
51
397
6
12
5.13
2.42
1.2
1.0
—
—
—
0
0
5
8
6.38
2.38
1.6
1.5
—
—
—
0
0
5
8
6.38
2.38
1.6
1.5
—
—
—
0
0
5
8
6.38
2.38
1.0
1.6
4.84
2.08
mmol/l
—
5
8
105
841
1.57
2.37
11.8
9.7
4.33
4.12
e9/l
0.45
90
740
153
1346
1.79
2.35
4.7
4.6
5.93
5.95
mmol/l
0.05
120
1221
6
13
4.73
2.29
1.7
1.6
—
—
—
0
0
65
470
1.59
2.26
3.2
3.5
2.36
2.35
mmol/l
0.02
58
414
81
617
1.56
2.25
5.4
4.4
34.53
35.59
g/l
0.72
66
574
8
24
3.44
2.20
1.5
1.6
—
—
—
0
0
17
81
2.21
2.20
2.1
1.5
—
—
—
0
0
19
95
2.11
2.20
1.4
1.5
—
—
—
0
0
6
14
4.39
2.17
1.7
1.6
—
—
—
0
0
6
14
4.39
2.17
1.7
1.6
—
—
—
0
0
6
14
4.39
2.17
1.7
1.6
—
—
—
0
0
6
14
4.39
2.17
1.7
1.6
—
—
—
0
0
6
14
4.39
2.17
1.7
1.6
—
—
—
0
0
151
1334
1.72
2.15
21.6
13.2
81.59
81.43
ml/min/173m2
0.03
133
1080
129
1100
1.57
2.09
9.5
7.3
77.81
78.75
u/l
0.08
113
1020
5
10
5.10
2.08
1.0
1.2
—
—
—
0
0
26
151
1.84
2.00
1.8
1.5
—
—
—
0
0
51
358
1.59
1.98
2.3
2.5
10324.28
5823.49
umol/l
0.18
43
306
8
27
3.05
1.96
1.4
1.4
—
—
—
0
0
5
11
4.64
1.95
1.6
1.5
—
—
—
0
0
26
154
1.80
1.88
1.8
1.6
—
—
—
0
0
154
1384
1.67
1.85
4.6
4.4
4.60
4.57
mmol/l
0.13
126
1277
153
1373
1.66
1.85
4.7
4.3
1.42
1.45
mmol/l
0.45
126
1251
170
1576
1.97
1.76
31.0
20.6
247.30
244.98
e9/l
0.17
158
1533
106
886
1.46
1.74
3.3
3.0
—
—
—
0
0
5
13
3.92
1.72
1.0
1.2
239.20
319.51
u/l
—
5
13
170
1578
1.95
1.72
31.7
20.6
39.70
40.15
%
0.59
157
1478
79
626
1.46
1.71
12.4
5.3
1.21
1.21
mmol/l
0.36
72
566
170
1579
1.95
1.70
31.1
20.6
4.39
4.49
e12/l
1.46
157
1531
36
241
1.61
1.69
1.7
1.5
—
—
—
0
0
170
1580
1.94
1.68
31.4
20.7
131.50
135.23
g/l
2.27
159
1550
11
49
2.32
1.67
4.2
2.0
—
—
—
0
0
112
954
1.44
1.61
3.5
3.0
75.36
47.34
u/l
0.54
97
903
59
446
1.47
1.61
2.8
2.4
48.65
56.59
u/l
1.67
51
409
155
1410
1.61
1.60
5.0
4.8
2.71
2.68
mmol/l
0.10
124
1292
6
20
3.06
1.59
1.5
1.4
—
—
—
0
0
32
212
1.62
1.57
2.7
2.1
2.16
2.36
g/l
1.47
26
192
5
15
3.39
1.53
1.0
1.6
—
—
—
0
0
147
1327
1.52
1.51
4.2
3.9
1.27
1.25
mmol/l
0.13
123
1204
84
686
1.41
1.50
11.0
6.0
1.20
1.21
mmol/l
0.66
56
580
119
1033
1.43
1.49
3.9
4.1
14.78
14.82
pmol/l
0.07
99
925
50
371
1.48
1.49
1.7
1.6
1.26
1.30
mmol/l
0.09
30
309
57
435
1.45
1.47
3.8
3.1
1506.08
1258.76
ng/l
0.22
44
372
156
1429
1.58
1.47
23.1
13.9
23.22
23.29
mg/l
0.01
139
1122
34
233
1.56
1.45
3.1
2.1
10.85
14.28
umol/l
2.39
29
216
21
127
1.74
1.44
4.5
3.6
5.86
5.65
kpa
0.31
21
122
6
23
2.66
1.38
1.5
1.4
—
—
—
0
0
138
1239
1.45
1.37
25.5
16.9
14.12
14.82
%
1.65
126
1220
162
1506
1.61
1.32
12.9
10.3
26.87
25.77
u/l
0.33
149
1453
11
56
2.03
1.25
1.9
1.8
—
—
—
0
0
89
752
1.35
1.23
6.0
6.3
9.78
11.65
umol/l
1.84
82
714
5
19
2.67
1.22
1.0
1.5
—
—
—
0
0
5
19
2.67
1.22
1.4
1.2
—
—
—
0
0
17
103
1.72
1.17
4.4
3.7
96.73
82.76
ng/l
0.25
11
91
11
58
1.95
1.14
1.9
1.9
—
—
—
0
0
156
1452
1.47
1.11
25.9
15.7
139.44
139.57
mmol/l
0.23
144
1406
140
1282
1.38
1.07
6.4
5.8
39.61
40.05
mmol/mol
0.20
116
1190
156
1455
1.46
1.07
26.2
15.8
3.98
3.97
mmol/l
0.08
144
1405
7
35
2.04
1.01
1.9
1.4
—
—
—
0
0
69
575
1.32
1.00
2.4
2.2
82.35
76.71
nmol/l
0.85
58
498
17
110
1.60
0.94
5.0
2.8
5.48
4.40
kpa
1.24
17
105
6
30
2.03
0.87
1.2
1.2
—
—
—
0
0
31
239
1.36
0.75
1.4
1.2
34.09
32.50
iu/ml
—
8
84
7
39
1.83
0.73
1.1
1.2
—
—
—
0
0
158
1502
1.36
0.72
23.3
16.1
78.73
77.97
umol/l
0.15
158
1502
59
501
1.26
0.72
6.2
4.7
2.11
2.12
ug/l
0.00
47
439
7
40
1.78
0.72
1.1
2.2
96.29
88.67
%
—
7
40
7
42
1.69
0.69
2.0
1.5
—
—
—
0
0
7
42
1.69
0.69
1.4
2.0
—
—
—
0
0
5
28
1.81
0.66
2.0
1.5
—
—
—
0
0
136
1280
1.24
0.59
4.7
4.8
1.83
1.91
mu/l
0.45
114
1152
6
37
1.64
0.56
1.0
1.5
—
—
—
0
0
49
420
1.23
0.55
5.4
3.6
6.16
9.91
mg/mmol
0.55
16
259
6
38
1.60
0.55
1.3
1.2
—
—
—
0
0
9
62
1.47
0.54
2.9
2.4
—
—
—
0
0
12
168
0.69
0.53
13.6
8.6
—
—
—
0
0
30
244
1.27
0.52
3.8
2.5
1.74
0.95
e6/l
0.26
17
147
33
272
1.26
0.52
2.5
1.7
1348.56
1204.20
nmol/l
0.39
16
211
11
76
1.48
0.49
4.5
2.6
0.93
1.28
%
1.07
11
76
11
76
1.48
0.49
3.3
2.4
—
—
—
0
0
28
228
1.27
0.49
3.8
2.6
0.81
1.77
e6/l
0.65
13
133
7
49
1.45
0.46
1.9
1.7
286.00
398.00
ug/l
—
7
44
54
476
1.19
0.46
2.4
3.1
31.91
32.32
u/l
0.04
46
449
27
221
1.26
0.45
1.3
1.3
21.40
10.00
u/ml
—
8
92
7
50
1.42
0.45
2.3
1.4
—
0.08
—
0
9
32
268
1.23
0.45
3.9
3.3
197.26
179.49
ng/l
0.04
19
205
62
557
1.17
0.42
2.3
2.0
102.38
94.17
pmol/l
0.82
34
281
5
33
1.53
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
3.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
1.19
—
0
9
5
34
1.48
0.40
2.2
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
—
—
0
0
0
19
0.00
0.39
0.0
4.0
—
91.32
—
0
19
10
72
1.41
0.37
4.9
2.6
0.65
0.67
%
—
10
72
34
293
1.20
0.37
2.7
2.8
0.67
0.71
ug/l
0.24
25
185
20
163
1.25
0.36
2.1
2.0
—
—
—
0
0
6
43
1.41
0.35
2.7
1.4
0.22
0.26
g/l
—
6
43
6
46
1.31
0.33
2.7
1.4
1.08
1.16
g/l
—
6
46
6
47
1.29
0.32
1.7
1.7
—
—
—
0
0
21
175
1.23
0.32
2.1
2.2
—
—
—
0
0
8
65
1.24
0.27
1.1
1.0
—
—
—
0
0
24
209
1.17
0.24
1.7
1.4
—
—
—
0
0
5
42
1.20
0.21
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
38.00
—
0
5
0
13
0.00
0.21
0.0
1.0
—
506.20
—
0
5
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
3.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
71
674
1.09
0.18
2.8
2.5
—
—
—
0
0
14
163
0.85
0.18
4.5
5.1
34.67
32.47
%
—
9
102
37
341
1.11
0.17
2.4
2.1
—
—
—
0
0
5
68
0.73
0.17
2.0
1.6
—
—
—
0
0
7
88
0.79
0.15
1.3
1.3
—
—
—
0
0
12
103
1.18
0.14
1.7
2.6
78.80
60.40
ml/min/173m2
—
5
42
29
309
0.93
0.10
1.2
1.2
0.68
1.05
u/ml
—
8
94
39
406
0.95
0.07
4.5
4.1
22.05
21.63
%
0.07
17
195
17
161
1.06
0.03
25.2
5.9
12.51
11.97
kpa
0.14
17
153
17
161
1.06
0.03
25.2
5.9
5.29
5.05
kpa
0.38
17
152
11
118
0.93
0.03
1.6
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
1.30
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
9.46
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.6
—
102.71
—
0
7
5
50
1.00
-0.00
1.4
1.7
3.84
3.77
mg/l
—
5
36
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
37.97
—
0
6
0
7
0.00
-0.00
0.0
6.4
—
225.14
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
67
0.89
-0.00
2.0
2.4
36.83
42.99
u/l
—
6
58
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
-0.00
0.0
1.0
—
136.17
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
1610.29
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint H8_MASTNAS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H8_MASTNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H8_MASTNAS – Other/unspecified mastoiditis and related conditions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data