Hypermetropia

H7_HYPERMETRO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H52.0
  • Hospital discharge: ICD-9 3670
  • Hospital discharge: ICD-8 37001
  • Cause of death: ICD-10 H52.0
  • Cause of death: ICD-9 3670
  • Cause of death: ICD-8 37001

2 out of 7 registries used, show all original rules.

2963

4. Check minimum number of events

None

2963

5. Include endpoints

None

2963

6. Filter based on genotype QC (FinnGen only)

2839

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H52
Name in latin
Hyperopia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 43985 23830 20105
Only index persons 33198 18331 14867
Unadjusted period prevalence (%)
Whole population 0.63 0.68 0.56
Only index persons 0.63 0.67 0.57
Median age at first event (years)
Whole population 7.22 7.69 6.59
Only index persons 9.13 10.16 7.86

-FinnGen-

Key figures

All Female Male
Number of individuals 2839 1816 1023
Unadjusted period prevalence (%) 0.58 0.64 0.47
Median age at first event (years) 50.91 49.19 53.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2963
Matched controls
29597
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.4
ICD-10 Finland
Presbyopia
15.6
310.4
277
194
H52.2
ICD-10 Finland
Astigmatism
51.4
307.7
374
83
H53.0
ICD-10 Finland
Amblyopia ex anopsia
38.4
307.7
241
68
H52.0
ICD-10 Finland
Hypermetropia
5182.4
307.7
2816
109
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
42.3
196.1
118
29
H50.0
ICD-10 Finland
Convergent concomitant strabismus
776.1
151.6
148
*
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
130.1
124
*
H50.52
ICD-10 Finland
Exophoria
28.9
117.8
79
28
H50.30
ICD-10 Finland
Intermittent esotropy
384.5
112.2
112
*
CHC05
NOMESCO Finland
Iridotomy
9.7
92.4
109
116
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
78.3
639
2996
H50.31
ICD-10 Finland
Intermittent exotropia
202.6
76.5
79
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
74.2
71
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
360.3
70.9
71
*
XCK00
NOMESCO Finland
Perimetry
3.8
69.4
227
638
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
+∞
65.8
63
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.8
60.9
345
1345
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
60.6
58
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.1
59.5
747
4125
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
58.2
1161
7512
H50.51
ICD-10 Finland
Esophoria
103.7
46.9
51
5
H40.0
ICD-10 Finland
Glaucoma suspect
2.8
46.4
249
940
H50.2
ICD-10 Finland
Vertical strabismus
101.6
45.9
50
5
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
45.4
238
887
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
13.3
44.2
42
32
P85
ICPC
Mental retardation
12.2
41.0
41
34
H25.0
ICD-10 Finland
Senile incipient cataract
2.9
37.9
187
673
H54.7
ICD-10 Finland
Unspecified visual loss
8.7
37.8
48
56
R51.80
ICD-10 Finland
Headache
1.9
37.2
539
3073
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.3
36.9
96
228
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
33.9
820
5430
ZXA10
NOMESCO Finland
Bilateral
1.9
33.4
534
3133
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
33.4
32
*
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
32.3
31
*
H53.2
ICD-10 Finland
Diplopia
4.0
31.4
90
230
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
29.8
319
1628
CEC00
NOMESCO Finland
Recession of extraocular muscle
294.5
28.8
29
*
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
151.3
28.7
30
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
28.1
252
1201
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
26.9
224
1035
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
25.0
256
1282
CHD00
NOMESCO Finland
Laser trabeculoplasty
5.6
24.9
47
85
F83
ICD-10 Finland
Mixed specific developmental disorders
4.2
24.7
65
156
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
9.4
24.4
29
31
SPAT1301
SPAT
No procedures
1.5
23.2
877
6365
H51.1
ICD-10 Finland
Convergence insufficiency and excess
231.5
22.6
23
*
H52.1
ICD-10 Finland
Myopia
3.7
22.5
72
199
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
21.7
266
1421
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
21.7
1116
8602
UDC00
NOMESCO Finland
Ear microscopy
2.0
21.5
234
1198
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
21.0
294
1640
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
20.2
231
1203
R42
ICD-10 Finland
Dizziness and giddiness
1.6
20.2
552
3704
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
20.2
550
3688
AA1AD
NOMESCO Finland
CT of head and brain
1.6
19.8
603
4150
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
19.7
587
4019
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
7.1
19.5
29
41
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
19.0
690
4930
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
18.6
228
1216
H52.5
ICD-10 Finland
Disorders of accommodation
100.6
18.6
20
*
R62.0
ICD-10 Finland
Delayed milestone
3.5
18.4
62
178
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
18.1
2048
17994
WX704
NOMESCO Finland
Intubation
2.0
18.1
212
1114
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.1
18.0
176
865
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
33.1
17.9
23
7
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
33.1
17.9
23
7
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.9
17.9
32
55
H26.4
ICD-10 Finland
After-cataract
2.0
17.4
205
1078
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
17.0
327
2001
H50.9
ICD-10 Finland
Strabismus, unspecified
16.0
17.0
27
17
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
17.0
231
1276
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
16.8
507
3466
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
16.7
16
*
3503
FHL
Single muscle retroposition
+∞
16.7
16
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.2
16.5
142
665
XCH00
NOMESCO Finland
Eye pressure measurement
2.4
16.5
111
468
XA800
NOMESCO Finland
Neuropsychological investigation
2.2
16.1
140
658
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.2
15.9
63
201
WX720
NOMESCO Finland
Own respiration
2.2
15.7
127
580
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
15.6
15
*
SPAT1263
SPAT
Sampling
1.4
15.5
1148
9288
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
15.4
92
367
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
15.2
289
1761
L04AD01
ATC
ciclosporin; systemic
3.0
15.0
64
213
A02BC05
ATC
esomeprazole; systemic
1.4
15.0
943
7415
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
14.8
397
2638
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.5
977
7760
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.6
14.5
83
324
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
150.6
14.5
15
*
Z31.5
ICD-10 Finland
Genetic counselling
2.0
14.4
157
804
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
14.2
372
2459
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.1
14.1
141
701
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
14.0
724
5493
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
13.9
265
1617
TAB00
NOMESCO Finland
Lumbar puncture
2.1
13.8
127
611
602
Kela drug reimbursment
Children's severe malnutrition
3.6
13.8
44
122
N02AX02
ATC
tramadol; systemic, rectal
1.4
13.8
961
7662
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
13.7
225
1317
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
13.5
13
*
Z2445
NOMESCO Finland
Psychologist
1.9
13.5
161
851
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
13.4
139
700
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
13.3
1428
12144
XKC03
NOMESCO Finland
Water cystometry
2.6
13.2
74
286
N02BE01
ATC
paracetamol; systemic, rectal
1.4
13.2
2351
21590
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
13.2
377
2540
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.0
13.2
145
746
N05BA09
ATC
clobazam; oral
4.4
12.8
32
74
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.6
12.8
30
66
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.4
12.8
89
382
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
12.7
791
6180
E0000UV, ,
ATC
1.3
12.6
1140
9425
N03AX12
ATC
[U] gabapentin; oral
1.5
12.5
361
2438
G47.3
ICD-10 Finland
Sleep apnoea
1.5
12.4
480
3440
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
12.4
626
4714
Z94.0
ICD-10 Finland
Kidney transplant status
3.6
12.4
40
112
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
12.4
650
4930
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
12.3
229
1387
WX702
NOMESCO Finland
Supraglottic ventilation device
1.9
12.2
142
745
C07AA05
ATC
propranolol; systemic
1.4
12.1
519
3792
137
Kela drug reimbursment
Uraemia requiring dialysis
4.4
12.1
30
69
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
12.1
155
840
M79.6
ICD-10 Finland
Pain in limb
1.3
12.1
1026
8395
L17
ICPC
Foot/toe symptom/complaint
1.4
11.9
754
5893
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.7
11.9
37
101
M54.5
ICD-10 Finland
Low back pain
1.4
11.9
869
6947
B03XA01
ATC
erythropoietin; parenteral
4.4
11.9
29
66
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.7
11.8
64
244
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.5
11.8
40
116
127
Kela drug reimbursment
Transplant complication
3.0
11.8
51
172
R03AC02
ATC
salbutamol; inhalant
1.3
11.7
1471
12700
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
11.7
1198
10055
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
11.6
513
3767
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
11.5
145
782
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
11.4
173
989
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
3.3
11.3
42
129
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
11.3
336
2280
R35
ICD-10 Finland
Polyuria
1.9
11.3
142
766
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.9
11.2
139
745
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
11.2
304
2021
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
11.1
768
6077
H02AB06
ATC
prednisolone; systemic
1.3
11.0
1106
9236
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
11.0
603
4599
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
10.9
94
442
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.6
10.8
59
226
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
10.7
116
595
WX402
NOMESCO Finland
General anaesthesia
1.4
10.7
539
4050
G44.2
ICD-10 Finland
Tension-type headache
1.5
10.6
340
2344
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.3
10.5
77
339
B05DA
ATC
Isotonic solutions
4.5
10.5
25
56
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
10.4
10
*
37929
ICD-8 Finland
Blindness, one eye, specifically defined
32.6
10.3
13
*
N06AX11
ATC
mirtazapine; oral
1.3
10.3
775
6199
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.4
10.2
25
57
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
10.2
1160
9816
N05CF01
ATC
zopiclone; oral
1.4
10.2
669
5241
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
10.1
309
2107
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.1
10.1
27
66
SPAT1310
SPAT
Counselling related to known health issue
1.3
10.1
857
6970
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
10.1
226
1437
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
10.1
51
188
H50.8
ICD-10 Finland
Other specified strabismus
40.2
10.0
12
*
M03BX02
ATC
tizanidine; oral
1.3
9.9
1446
12622
H47.2
ICD-10 Finland
Optic atrophy
7.6
9.9
22
29
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.8
2023
18438
J02AC01
ATC
fluconazole; systemic
1.3
9.7
901
7409
J01DB01
ATC
cefalexin; oral
1.3
9.7
2231
20621
114
Kela drug reimbursment
Glaucoma
1.7
9.7
158
924
H57.1
ICD-10 Finland
Ocular pain
2.0
9.6
100
505
S06.0
ICD-10 Finland
Concussion
1.5
9.6
291
1984
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
4.6
9.5
22
48
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.5
9.4
59
242
3507
FHL
Retroposition and resection
100.2
9.4
10
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
9.4
222
1429
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
9.4
301
2074
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
17.6
9.4
14
8
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
9.4
9
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
9.4
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
9.4
232
1511
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
9.3
236
1547
C09CA06
ATC
candesartan; oral
1.4
9.2
493
3733
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.2
979
8191
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
9.1
346
2466
H01AC01
ATC
somatropin; parenteral
3.0
9.1
38
126
M54.2
ICD-10 Finland
Cervicalgia
1.7
9.1
182
1126
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
9.0
626
4933
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.1
9.0
36
116
N06AA09
ATC
amitriptyline; systemic
1.6
9.0
191
1199
SPAT1153
SPAT
Removal of sutures
1.3
9.0
685
5475
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
4.1
9.0
24
59
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
8.9
521
3999
Q21.10
ICD-10 Finland
Persistent ostium secundum
3.3
8.9
33
102
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.7
8.8
47
178
D06
ICPC
Abdominal pain localized other
1.5
8.8
239
1588
H53.3
ICD-10 Finland
Other disorders of binocular vision
4.5
8.8
21
47
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
8.8
153
911
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.5
8.8
55
226
H02AB09
ATC
hydrocortisone; systemic
2.1
8.8
79
379
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
8.8
316
2229
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.7
1424
12521
A11CC03
ATC
alfacalcidol; systemic
2.4
8.7
55
227
OAB50, ,
SPAT
1.8
8.7
120
668
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
50.1
8.7
10
*
RL140, ,
NOMESCO Finland
6.6
8.6
21
32
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
8.6
205
1322
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
3.3
8.6
32
99
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
16.3
8.5
13
8
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.1
8.5
74
350
M25.5
ICD-10 Finland
Pain in joint
1.3
8.5
765
6245
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.5
585
4605
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
8.4
229
1524
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
1.9
8.4
96
503
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.9
8.3
107
582
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
2.0
8.3
90
462
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
8.3
8
*
3504
FHL
Retroposition of two muscles
+∞
8.3
8
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
8.3
8
*
R52.9
ICD-10 Finland
Pain, unspecified
1.5
8.3
226
1504
ZXD20
NOMESCO Finland
Day surgery
1.5
8.2
287
2012
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.9
8.2
36
123
L04AA06
ATC
mycophenolic acid; systemic
2.5
8.2
49
197
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
2.8
8.2
40
145
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.6
8.2
170
1061
L03
ICPC
Low back symptom/complaint
1.3
8.2
680
5490
UKC02
NOMESCO Finland
Cystoscopy
1.5
8.2
286
2005
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.2
1964
18002
N17
ICPC
Vertigo/dizziness
1.5
8.1
289
2032
N06AX16
ATC
venlafaxine; oral
1.4
8.1
333
2406
KMAK, ,
NOMESCO Finland
1.3
8.1
1196
10366
H01
ICPC
Ear pain/earache
1.4
8.1
364
2674
A02BC02
ATC
pantoprazole; systemic
1.2
8.1
1564
13978
ZXE00
NOMESCO Finland
One hour or less
1.3
8.0
943
7958
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.5
8.0
47
188
S01EE01
ATC
latanoprost; ophthalmic
1.8
8.0
113
635
N03AG01
ATC
valproic acid; systemic, rectal
1.7
8.0
133
784
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
8.0
348
2544
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
7.2
7.9
18
25
K59.0
ICD-10 Finland
Constipation
1.7
7.9
130
762
RT150, ,
NOMESCO Finland
3.9
7.9
22
56
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
7.8
382
2845
R53
ICD-10 Finland
Malaise and fatigue
1.3
7.8
566
4481
Z99.2
ICD-10 Finland
Dependence on renal dialysis
9.4
7.8
15
16
N05BA01
ATC
diazepam; systemic, rectal
1.5
7.8
275
1933
G54.0
ICD-10 Finland
Brachial plexus disorders
2.2
7.7
63
291
S01ED51
ATC
timolol, combinations; ophthalmic
1.7
7.7
137
821
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.3
7.7
911
7681
N03AF02
ATC
oxcarbazepine; oral
2.0
7.7
82
419
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.5
7.7
48
197
B05DB
ATC
Hypertonic solutions
4.2
7.7
20
48
BE00A, ,
NOMESCO Finland
15.0
7.7
12
8
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.3
7.7
57
253
R5140
NOMESCO Finland
Monitoring the use of the aid
1.5
7.7
212
1416
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.3
7.7
19
44
L01
ICPC
Neck symptom/complaint
1.4
7.7
382
2855
XQ845
NOMESCO Finland
Dermatoscopy
2.5
7.6
44
174
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.6
692
5645
K07.60
ICD-10 Finland
Snapping jaw
1.7
7.6
136
817
H47.1
ICD-10 Finland
Papilloedema, unspecified
3.7
7.6
23
62
R02
ICPC
Shortness of breath/dyspnoea
1.4
7.6
293
2093
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
7.6
805
6699
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
11.9
7.6
13
11
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
25.0
7.6
10
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
25.0
7.6
10
*
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
8.9
7.5
15
17
N03AX14
ATC
levetiracetam; systemic
2.1
7.5
67
321
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.5
502
3928
R06AE07
ATC
cetirizine; oral
1.2
7.5
1123
9726
N05CF02
ATC
zolpidem; oral
1.4
7.5
355
2631
SAA04
NOMESCO Finland
Special examination of mouth
1.6
7.5
186
1214
N06AX05
ATC
trazodone; oral
2.2
7.5
60
276
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
7.5
371
2772
A02BC01
ATC
omeprazole; systemic
1.3
7.4
578
4619
N06AX21
ATC
duloxetine; oral
1.5
7.4
255
1783
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
7.4
203
1354
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.4
969
8266
SPAT1079
SPAT
Echocardiography
3.3
7.4
27
83
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.3
258
1811
H02.3
ICD-10 Finland
Blepharochalasis
1.7
7.3
125
742
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
7.3
7
*
Z3231
NOMESCO Finland
Registered nurse
1.3
7.3
678
5546
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
10.9
7.3
13
12
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
10.9
7.3
13
12
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
10.9
7.3
13
12
NF1DA
NOMESCO Finland
X-ray of hips
2.3
7.3
50
215
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.3
490
3837
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
7.3
238
1648
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
3.5
7.2
24
69
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
7.2
198
1320
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.4
7.2
46
191
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
7.2
467
3633
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.3
7.2
51
222
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
7.2
139
852
L08
ICPC
Shoulder symptom/complaint
1.3
7.2
471
3671
UJF32
NOMESCO Finland
Coloscopy
1.3
7.2
525
4156
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.1
7.2
66
320
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.5
7.2
255
1794
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.6
7.2
144
893
R52.2
ICD-10 Finland
Other chronic pain
1.9
7.1
82
431
SPAT1009
SPAT
Measurement of intraocular pressure
2.8
7.1
34
122
R4120
NOMESCO Finland
Occupational therapy
1.6
7.1
153
964
183
Kela drug reimbursment
Lamotrigin and topiramate
3.1
7.1
28
90
N03AX16
ATC
[U] pregabalin
1.3
7.1
472
3687
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
7.1
290
2094
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
2.8
7.1
33
117
H43.3
ICD-10 Finland
Other vitreous opacities
2.8
7.1
33
117
N05BA04
ATC
oxazepam; oral
1.3
7.1
561
4491
SPAT1395
SPAT
Health check-up of persons outside student and working life
2.2
7.1
57
263
N05AH04
ATC
quetiapine; oral
1.3
7.0
427
3291
XCW10
NOMESCO Finland
Assessment of vision
3.1
7.0
28
91
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.9
1598
14445
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
2.2
6.9
55
252
J05AB01
ATC
aciclovir; systemic
1.3
6.9
483
3799
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.2
6.9
54
246
N03AX11
ATC
topiramate; oral
2.1
6.9
61
292
-1, ,
NOMESCO Finland
1.2
6.9
983
8448
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.2
6.8
26
82
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.5
6.8
185
1232
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.7
6.8
111
651
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
3.8
6.8
20
53
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
6.8
117
698
R06.4
ICD-10 Finland
Hyperventilation
2.5
6.7
39
155
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.8
6.7
100
571
L04AX01
ATC
azathioprine; systemic
1.8
6.7
97
549
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
6.7
204
1391
XF602
NOMESCO Finland
Bloodpressure monitoring
2.6
6.7
36
138
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
3.3
6.7
24
73
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
22.5
6.7
9
*
SPAT1312
SPAT
General health counselling
1.2
6.7
894
7625
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.0
6.7
65
323
N18.8
ICD-10 Finland
Other chronic renal failure
2.3
6.7
47
205
N06AB04
ATC
citalopram; systemic
1.3
6.7
413
3193
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.6
789
6637
R11
ICD-10 Finland
Nausea and vomiting
1.5
6.6
227
1587
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
4.0
6.6
18
45
H27.8
ICD-10 Finland
Other specified disorders of lens
7.8
6.6
14
18
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
6.6
351
2652
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.6
771
6476
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.6
583
4734
XX4AW, ,
NOMESCO Finland
3.2
6.5
25
79
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.5
597
4867
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
6.5
390
2999
F81.0
ICD-10 Finland
Specific reading disorder
3.0
6.5
27
90
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
6.5
478
3787
H53.9
ICD-10 Finland
Visual disturbance, unspecified
1.9
6.5
73
382
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
6.5
1191
10497
H47.3
ICD-10 Finland
Other disorders of optic disc
5.7
6.4
17
30
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
69.9
6.4
7
*
H40.11
ICD-10 Finland
Low pressure glaucoma
2.4
6.4
40
165
WX892
NOMESCO Finland
Monitored bed care
1.6
6.4
163
1070
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.4
886
7576
Z2446
NOMESCO Finland
Social worker
1.5
6.4
195
1331
G81.9
ICD-10 Finland
Hemiplegia, unspecified
3.2
6.4
24
75
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.6
6.4
137
864
R06.5
ICD-10 Finland
Mouth breathing
1.5
6.4
202
1390
R51.81
ICD-10 Finland
Facial pain NOS
2.1
6.3
54
255
H53.4
ICD-10 Finland
Visual field defects
2.4
6.3
40
166
SPAT1097
SPAT
Recording of ECG
1.4
6.3
281
2059
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
1.8
6.3
84
464
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
6.3
962
8308
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
6.3
241
1719
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
5.2
6.3
18
35
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
6.3
997
8646
EB1VA, ,
NOMESCO Finland
1.4
6.3
269
1959
Z3226
NOMESCO Finland
Physiotherapist
1.3
6.3
429
3362
N03AG04
ATC
vigabatrin; oral
9.3
6.3
12
13
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
3.3
6.3
22
66
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
2.9
6.3
27
92
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
6.2
6
*
B34.9
ICD-10 Finland
Viral infection, unspecified
1.7
6.2
99
577
J01CA04
ATC
amoxicillin; systemic
1.3
6.2
2350
22244
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.5
6.2
207
1439
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.4
6.2
266
1939
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.0
6.2
61
305
Z94.4
ICD-10 Finland
Liver transplant status
5.0
6.2
18
36
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
2.3
6.2
43
187
N92.2
ICD-10 Finland
Excessive menstruation at puberty
3.5
6.1
20
57
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
6.1
89
506
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.9
6.1
72
383
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.6
6.1
138
883
181
Kela drug reimbursment
Retigabine and vigabatrin
12.5
6.1
10
8
WYA10
NOMESCO Finland
Emergency care or similar visit
1.5
6.1
187
1280
ZXA05
NOMESCO Finland
Left side
1.3
6.0
486
3895
N07BA03
ATC
varenicline; oral
1.7
6.0
95
553
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
6.0
188
1291

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1950
16301
1.57
28.42
5.5
4.1
—
—
—
0
0
2012
17177
1.53
24.56
7.8
7.0
80.29
81.60
u/l
0.58
1906
16187
1205
9300
1.50
23.90
5.9
5.0
36.21
36.05
g/l
0.44
1124
8645
868
6268
1.54
23.52
4.7
3.8
7.40
7.40
ph
0.04
185
1210
1394
11106
1.48
23.44
9.2
7.0
1.22
1.22
mmol/l
0.25
1150
9544
2002
17260
1.49
21.72
4.8
4.0
10.62
11.09
mm/h
0.92
1859
15997
2134
18754
1.49
20.05
4.7
3.9
14.59
14.66
pmol/l
0.70
1945
17062
1828
15619
1.44
19.71
5.8
4.2
3860.92
1932.76
e6/l
0.32
24
186
1272
10185
1.43
19.59
8.4
6.6
1.22
1.22
mmol/l
0.58
1149
9344
1192
9451
1.43
19.28
4.0
3.2
5.98
5.92
ph
0.26
73
800
1601
13391
1.42
19.17
5.9
4.9
6.35
6.55
mmol/l
3.64
1483
12411
827
6154
1.47
18.56
2.2
2.2
168.14
223.27
u/l
1.82
781
5785
373
2313
1.70
18.53
2.6
2.2
364.27
369.53
nmol/l
0.17
342
2120
2425
22029
1.55
18.15
5.4
4.6
1.92
2.03
mu/l
0.54
2242
20369
1406
11614
1.40
17.40
4.5
3.5
0.00
0.00
estimate
0.99
308
2344
1373
11298
1.40
17.37
6.1
6.2
11.93
12.11
umol/l
0.12
1293
10643
1409
11704
1.39
16.55
4.5
3.5
0.01
0.00
estimate
0.25
291
2193
1398
11604
1.39
16.47
6.1
4.7
0.00
0.00
estimate
0.41
299
2252
885
6802
1.43
16.32
2.7
2.5
57.72
69.48
u/l
0.49
827
6270
1750
15205
1.37
14.79
3.9
3.4
—
—
—
0
0
1379
11547
1.36
14.78
8.6
6.8
—
—
—
0
0
120
552
2.22
14.58
1.8
2.2
—
—
—
0
0
2603
24289
1.58
14.53
15.7
12.6
21.38
22.77
mg/l
1.35
2070
18605
1185
9718
1.36
14.39
3.0
2.4
75.89
74.95
nmol/l
0.54
1076
8822
1491
12695
1.35
14.05
7.8
6.6
0.20
0.19
e9/l
0.36
1324
11090
128
618
2.12
13.79
5.8
6.1
1.19
1.28
mmol/l
0.42
115
530
54
173
3.16
13.55
1.6
1.6
—
—
—
0
0
2582
24120
1.54
13.54
17.5
14.2
3.95
3.95
mmol/l
0.24
2522
23388
1444
12278
1.34
13.53
7.4
6.3
0.04
0.04
e9/l
0.32
1274
10563
1442
12259
1.34
13.52
7.5
6.3
0.57
0.57
e9/l
0.05
1273
10555
2577
24070
1.53
13.45
17.5
14.1
139.69
139.62
mmol/l
0.75
2518
23394
1136
9345
1.35
13.18
14.5
13.2
1.24
1.22
inr
0.42
386
2783
132
660
2.04
12.97
1.7
2.0
381.12
504.50
mg/l
4.12
124
628
453
3194
1.49
12.77
9.9
6.8
1.10
1.11
mmol/l
0.34
425
2975
886
7051
1.36
12.62
3.7
2.8
—
—
—
0
0
497
3577
1.47
12.62
1.8
1.7
1206.45
1176.26
nmol/l
0.31
375
2696
2848
27370
2.02
12.48
22.9
18.5
40.06
40.19
%
0.25
2594
25807
272
1718
1.64
12.45
5.5
3.9
1.23
1.23
mmol/l
0.88
226
1483
2850
27406
2.02
12.30
22.6
18.3
6.66
6.71
e9/l
0.64
2783
26523
2673
25260
1.58
12.24
14.5
11.5
—
—
—
0
0
103
480
2.18
12.17
5.7
3.9
—
—
—
0
0
2849
27401
2.00
12.17
22.6
18.2
90.01
89.99
fl
0.07
2816
27005
106
500
2.16
12.15
3.9
3.6
55.52
56.16
%
0.18
106
500
2849
27402
2.00
12.15
22.5
18.2
30.03
30.02
pg
0.19
2816
27007
1473
12679
1.32
12.15
7.5
6.3
1.96
2.02
e9/l
0.86
1315
11192
2850
27417
2.01
12.12
22.8
18.4
134.53
134.82
g/l
0.52
2817
27025
2849
27406
2.00
12.08
22.6
18.3
4.51
4.51
e12/l
0.42
2781
26519
57
203
2.84
11.93
1.1
1.1
205.30
253.82
mg/l
1.26
46
174
58
210
2.79
11.78
1.2
1.2
28.20
38.99
mg/l
1.60
43
170
2846
27388
1.96
11.73
22.7
18.3
256.44
256.89
e9/l
0.14
2783
26571
2666
25217
1.56
11.71
11.3
9.6
26.16
25.75
u/l
0.21
2575
24338
540
4000
1.43
11.68
3.7
3.6
142.92
474.15
ng/l
6.51
379
2876
119
596
2.04
11.67
1.6
2.0
3.53
3.66
mmol/l
1.09
111
565
2190
20013
1.36
11.57
5.4
5.1
38.32
38.95
mmol/mol
2.71
2030
18617
1321
11254
1.31
11.50
7.7
6.5
0.67
0.67
%
0.21
1250
10553
1609
14090
1.31
11.39
10.0
9.0
3.87
3.95
e9/l
0.75
1427
12234
119
603
2.01
11.31
1.8
2.1
8.53
26.14
e6/l
0.96
86
450
931
7566
1.33
11.28
3.6
3.4
289.03
52.24
ng/l
0.46
545
4763
138
737
1.91
11.27
5.1
5.5
1.74
1.62
%
0.53
127
679
1355
11605
1.31
11.26
7.7
6.4
2.98
2.88
%
0.65
1287
10895
119
604
2.01
11.26
1.8
2.2
1490.72
1166.81
e6/l
0.12
93
475
911
7391
1.33
11.14
3.6
3.2
2.35
2.36
mmol/l
1.09
817
6544
1360
11680
1.30
10.97
7.9
6.7
8.56
8.43
%
0.79
1291
10978
1031
8530
1.32
10.94
1.9
1.9
98.06
95.34
pmol/l
1.10
521
4451
136
732
1.90
10.86
5.2
5.5
0.94
0.90
%
0.60
127
677
628
4831
1.38
10.81
3.9
2.6
6.81
6.77
e6/l
0.02
568
4319
604
4617
1.39
10.81
3.7
2.8
529.61
550.36
mosm/kgh2o
1.45
518
3963
794
6343
1.34
10.71
4.4
3.1
—
—
—
0
0
89
417
2.17
10.43
6.3
7.3
11.21
11.34
mmol/l
0.12
81
367
1399
12116
1.29
10.37
7.7
6.4
29.75
29.84
%
0.10
1332
11434
89
418
2.16
10.37
6.3
7.3
105.05
105.25
mmol/l
0.13
81
368
1379
11926
1.29
10.31
7.3
6.3
55.26
55.38
%
0.14
1303
11245
773
6199
1.33
10.05
5.2
3.8
0.00
0.00
estimate
1.28
285
2183
916
7524
1.31
10.05
3.9
3.3
34.01
34.27
u/l
0.02
863
7146
302
2059
1.52
9.92
5.7
3.8
—
—
—
0
0
92
446
2.09
9.90
3.4
2.7
16.34
16.54
%
0.19
54
231
793
6405
1.32
9.76
1.5
1.4
1.84
2.02
u/ml
0.11
200
1563
37
116
3.21
9.70
1.6
1.1
75.86
70.92
%
—
7
13
163
963
1.73
9.61
1.9
1.7
9.14
8.01
u/l
0.58
125
727
472
3534
1.40
9.45
6.0
4.7
0.82
0.82
mmol/l
0.11
437
3342
721
5778
1.33
9.31
1.8
1.7
1.34
1.36
mmol/l
0.27
612
4935
81
385
2.13
9.19
6.7
3.7
—
—
—
0
0
97
495
1.99
9.10
6.1
4.7
2.05
2.45
mmol/l
0.87
65
327
431
3206
1.40
8.94
1.4
1.3
442.56
524.76
titre
0.49
78
622
733
5923
1.31
8.86
2.3
2.4
2.89
2.87
mg/l
0.08
622
5081
1276
11067
1.27
8.83
3.4
2.8
99.29
99.35
ug/l
0.00
1183
10312
80
386
2.10
8.75
7.2
3.4
—
—
—
0
0
668
5340
1.32
8.70
3.3
2.7
2745.54
4955.92
umol/l
1.00
574
4728
602
4765
1.33
8.37
1.6
1.5
20.00
20.73
nmol/l
0.68
513
4090
245
1667
1.51
8.12
5.8
4.5
78.19
78.03
ng/l
0.01
220
1480
147
886
1.69
8.10
16.6
10.0
1.46
1.29
mg/l
1.81
136
840
450
3424
1.37
8.10
3.3
2.4
13.00
13.51
umol/l
0.80
419
3196
242
1644
1.51
8.08
3.3
3.2
154.54
189.98
ng/l
1.16
225
1482
107
594
1.83
7.84
5.9
4.3
7.42
7.42
ph
0.26
100
530
637
5127
1.31
7.80
4.4
3.7
1.02
1.02
kg/l
0.76
102
786
448
3432
1.36
7.71
2.4
2.8
29.40
29.95
s
1.57
437
3339
620
4980
1.31
7.70
2.0
2.1
1.08
1.21
mg/l
0.51
459
3688
1703
15420
1.24
7.59
3.5
3.1
43.13
43.15
u/l
0.00
1583
14490
236
1618
1.50
7.55
2.4
2.2
10.80
11.54
nmol/l
0.64
212
1439
264
1855
1.46
7.47
1.2
1.2
122.21
155.53
iu/ml
0.82
101
665
342
2520
1.40
7.46
8.2
5.6
7.37
7.38
ph
—
6
15
2304
21623
1.29
7.43
4.4
4.0
5.72
5.81
mmol/l
3.02
2090
19765
2308
21669
1.29
7.40
19.0
15.1
14.23
14.48
%
1.70
2278
21269
271
1922
1.45
7.31
3.0
2.9
9.78
10.20
g/l
1.04
251
1765
410
3134
1.36
7.13
3.4
2.4
2.43
2.40
g/l
0.44
380
2899
167
1076
1.58
7.10
9.1
10.7
—
—
—
0
0
217
1487
1.49
6.97
3.3
3.2
4.59
4.63
pmol/l
0.22
196
1314
384
2922
1.36
6.87
3.5
2.5
21.64
22.90
%
1.00
313
2534
287
2082
1.42
6.84
14.0
8.7
8.09
8.19
mmol/l
0.11
279
2002
334
2488
1.38
6.82
8.2
5.5
5.88
5.83
kpa
0.52
321
2409
333
2480
1.38
6.81
8.2
5.5
1.73
1.67
mmol/l
0.13
277
2025
493
3915
1.31
6.57
1.3
1.3
35.87
32.68
iu/ml
0.14
140
1187
17
41
4.16
6.53
2.8
2.7
—
—
—
0
0
179
1198
1.52
6.45
6.9
6.7
24.23
24.42
mmol/l
0.29
169
1132
401
3104
1.34
6.40
2.0
2.0
—
—
—
0
0
685
5692
1.26
6.37
1.6
1.5
1.98
2.13
g/l
1.94
407
3323
253
1822
1.42
6.29
7.5
8.4
121.89
122.22
g/l
0.09
245
1768
185
1256
1.50
6.24
4.9
4.7
—
—
—
0
0
379
2922
1.34
6.21
1.3
1.2
—
—
—
0
0
675
5615
1.26
6.20
4.4
4.2
—
—
—
0
0
827
7041
1.24
6.18
4.7
3.2
54.91
67.54
e6/l
0.32
663
5355
319
2397
1.37
6.18
1.2
1.2
—
—
—
0
0
61
305
2.02
6.17
2.1
2.2
—
—
—
0
0
535
4332
1.29
6.13
1.8
1.6
434.47
29097885.80
pmol/l
3.54
436
3612
127
797
1.62
6.07
1.4
1.3
—
—
—
0
0
212
1489
1.45
6.04
1.3
1.3
24.45
56.19
au/ml
—
6
75
1234
10984
1.21
5.89
2.6
2.6
—
—
—
0
0
251
1831
1.40
5.81
1.4
1.3
268.15
228.38
u/ml
0.32
224
1699
207
1463
1.44
5.72
2.8
2.3
10900.90
6327.50
u/l
0.71
60
538
644
5375
1.25
5.70
3.1
3.2
1056.17
1233.68
ng/l
0.79
536
4518
227
1633
1.42
5.70
2.4
2.3
22.25
22.17
au/ml
—
8
114
2319
21985
1.25
5.65
4.5
4.0
4.65
4.66
mmol/l
0.21
2134
20521
238
1730
1.41
5.63
4.0
4.0
0.73
0.65
%
0.19
80
542
71
387
1.85
5.62
1.8
1.6
—
—
—
0
0
462
3712
1.29
5.60
1.3
1.2
6.36
10.64
u/ml
0.91
162
1432
87
506
1.74
5.56
2.9
2.4
127.15
131.45
g/l
1.01
73
385
31
122
2.55
5.52
41.3
36.5
6.39
7.07
ug/l
1.54
26
110
661
5555
1.24
5.48
4.0
3.4
—
—
—
0
0
428
3424
1.29
5.36
2.1
2.6
86.20
118.09
ug/g
2.80
338
2707
211
1517
1.42
5.33
1.2
1.2
386.00
171.14
titre
—
5
50
285
2157
1.35
5.28
8.5
5.3
4.91
4.79
kpa
0.32
274
2088
249
1848
1.38
5.22
3.2
3.0
62.82
69.67
e9/l
2.57
182
1358
464
3765
1.27
5.18
3.2
2.9
2.45
2.45
mmol/l
0.20
406
3281
130
855
1.54
5.14
1.3
1.2
0.28
0.84
u/ml
—
9
64
960
8430
1.20
5.10
5.4
3.7
73.75
97.07
e6/l
0.54
695
5773
212
1538
1.41
5.09
1.3
1.4
—
—
—
0
0
266
2004
1.36
5.08
7.6
8.3
95.99
95.66
%
0.29
256
1929
116
746
1.58
5.06
1.1
1.1
4.24
8.88
u/ml
0.73
11
106
294
2254
1.34
5.01
7.3
7.8
0.84
0.98
mmol/l
0.22
225
1755
57
301
1.91
5.01
3.4
2.6
1.51
1.34
e9/l
0.45
50
254
206
1492
1.41
5.00
1.3
1.2
—
—
—
0
0
231
1706
1.38
5.00
4.5
4.4
0.04
0.28
%
0.62
68
438
2339
22281
1.23
4.97
4.9
4.4
2.75
2.76
mmol/l
0.21
2152
20655
103
648
1.61
4.93
1.8
1.7
40.69
39.71
nmol/l
0.10
103
628
20
66
3.04
4.93
2.5
2.6
—
—
—
0
0
294
2262
1.33
4.89
7.3
7.8
5.09
5.11
kpa
0.07
278
2159
350
2760
1.30
4.88
1.8
1.7
—
—
—
0
0
162
1128
1.46
4.88
1.8
1.6
292.14
314.73
mu/l
0.51
144
1008
324
2531
1.31
4.84
3.8
3.2
1.49
1.70
%
5.13
282
2269
293
2262
1.33
4.76
7.3
7.8
13.21
12.78
kpa
0.58
277
2161
173
1226
1.43
4.76
1.9
1.6
24.70
22.37
iu/l
0.35
135
969
102
648
1.59
4.71
1.3
1.4
299.86
301.81
ug/g
0.03
58
367
1235
11153
1.18
4.68
12.1
9.3
0.00
0.00
e9/l
0.17
1034
9032
103
658
1.58
4.65
2.7
2.5
—
—
—
0
0
253
1920
1.35
4.63
9.2
5.7
7.41
7.41
ph
0.32
38
174
249
1886
1.35
4.61
4.5
4.3
1.01
0.91
%
0.16
88
621
2289
21805
1.21
4.60
4.4
4.0
1.48
1.47
mmol/l
0.25
2100
20242
292
2266
1.32
4.58
9.3
8.9
—
—
—
0
0
750
6490
1.21
4.57
4.4
3.1
0.33
0.40
e6/l
0.58
592
4891
326
2578
1.30
4.46
1.4
1.5
—
—
—
0
0
741
6427
1.20
4.39
4.4
3.1
—
—
—
0
0
237
1805
1.34
4.25
4.5
4.3
0.14
0.12
%
0.11
74
539
25
103
2.44
4.12
2.8
1.9
—
—
—
0
0
61
352
1.75
4.10
1.6
1.6
—
—
—
0
0
2204
21011
1.19
3.97
4.0
3.6
1.26
1.27
mmol/l
0.21
2022
19393
2253
21521
1.19
3.95
19.5
15.8
333.46
332.92
g/l
2.06
2243
21341
217
1651
1.34
3.93
9.1
6.0
23.81
23.88
mmol/l
0.14
211
1632
325
2615
1.27
3.89
3.3
3.5
5.33
7.34
umol/l
3.67
266
2246
208
1577
1.34
3.86
3.1
2.8
66.00
66.34
g/l
0.30
186
1447
777
6853
1.18
3.73
4.0
3.3
7.30
7.78
mmol/l
2.13
673
5913
68
417
1.64
3.69
1.7
1.5
0.29
0.39
nmol/l
0.62
61
321
14
40
3.51
3.60
1.1
1.1
0.64
0.71
umol/24h
—
7
26
44
241
1.84
3.55
3.5
2.6
575.97
552.03
e6/l
0.10
35
190
56
330
1.71
3.54
2.0
2.9
—
—
—
0
0
22
93
2.37
3.47
1.3
1.3
—
—
—
0
0
58
351
1.66
3.35
1.5
1.4
16.10
21.02
u/l
0.86
53
289
136
988
1.39
3.34
2.7
3.6
22.60
21.90
s
0.67
112
884
668
5868
1.18
3.33
4.7
4.4
90.06
90.72
%
0.28
656
5728
55
330
1.68
3.28
3.4
3.5
1.50
1.27
%
0.20
49
299
33
169
1.96
3.27
4.2
2.9
300.83
300.92
e6/l
0.00
24
109
25
116
2.16
3.21
1.1
1.1
0.40
4.46
nmol/l
—
5
24
35
628
0.55
3.15
2.6
2.4
—
—
—
0
0
42
237
1.78
3.12
3.6
2.6
0.28
0.20
e9/l
0.78
35
190
30
152
1.98
3.08
3.7
4.3
1.82
1.58
ug/l
0.24
30
144
122
884
1.39
3.07
6.0
4.5
0.35
0.32
g/l
0.16
67
444
15
56
2.68
3.05
1.2
1.3
—
—
—
0
0
16
62
2.59
3.03
2.6
2.2
20.71
17.20
umol/l
0.38
16
62
82
553
1.49
3.02
2.2
2.1
10.42
11.51
mg/l
0.60
74
509
46
270
1.71
3.00
1.7
2.1
—
—
—
0
0
9
21
4.29
2.99
1.2
1.2
—
—
—
0
0
650
5744
1.17
2.98
3.3
3.3
952.30
334.23
mg/l
1.32
400
3700
22
100
2.21
2.98
1.1
1.1
145.20
278.52
ng/l
—
5
21
587
5150
1.17
2.95
5.1
4.7
2.76
2.49
ug/l
0.16
529
4602
375
3164
1.21
2.93
1.7
1.6
—
—
—
0
0
55
344
1.61
2.84
5.6
5.1
433.13
369.69
umol/l
2.16
48
304
101
719
1.42
2.84
2.0
1.7
0.23
0.23
g/l
0.08
89
681
528
4610
1.18
2.81
1.8
1.7
—
—
—
0
0
41
239
1.72
2.76
1.7
1.6
52.13
59.83
%
0.54
23
157
5
6
8.34
2.75
4.0
6.3
—
—
—
0
0
456
3941
1.18
2.75
3.5
2.7
0.81
1.19
e6/l
1.74
268
2209
268
2201
1.24
2.74
2.7
2.7
0.21
0.22
g/l
0.15
253
2063
45
271
1.67
2.71
2.6
1.6
283.66
284.88
mosm/kgh2o
0.13
32
208
71
479
1.49
2.65
1.2
1.2
61.00
49.05
u/ml
—
5
43
673
6015
1.15
2.64
3.9
3.8
14.07
12.08
mg/mmol
0.21
410
3832
45
275
1.64
2.57
1.2
1.7
40.18
85.21
mu/l
0.68
39
252
102
742
1.39
2.56
2.0
1.7
1.14
1.17
g/l
0.75
90
705
12
42
2.86
2.54
1.3
3.0
—
—
—
0
0
68
460
1.49
2.52
1.5
1.4
3.69
4.92
ug/l
0.93
62
427
190
1522
1.26
2.44
9.8
5.8
—
—
—
0
0
42
257
1.64
2.41
1.3
1.5
365.94
409.66
pmol/l
0.24
34
226
87
625
1.40
2.37
2.4
1.6
—
—
—
0
0
188
1512
1.26
2.35
2.0
1.8
1.24
1.29
g/l
0.12
172
1403
653
5878
1.14
2.29
3.8
3.6
—
—
—
0
0
271
2274
1.21
2.28
1.4
1.4
—
—
—
0
0
6
13
4.62
2.27
1.3
1.5
—
—
—
0
0
77
547
1.42
2.25
1.1
1.1
—
—
—
0
0
136
1059
1.30
2.21
2.3
2.4
—
—
—
0
0
16
74
2.17
2.14
1.9
1.8
—
—
—
0
0
645
5831
1.13
2.11
2.1
2.0
—
—
—
0
0
82
602
1.37
2.01
2.1
1.9
4.64
4.53
iu/l
0.04
31
213
81
594
1.37
2.00
2.5
1.6
100.66
108.87
u/ml
0.27
19
90
89
663
1.35
2.00
4.7
2.4
—
—
—
0
0
40
255
1.57
2.00
2.3
3.0
—
—
—
0
0
94
707
1.34
1.98
1.8
2.6
343.68
387.71
ug/l
0.15
85
666
40
256
1.57
1.97
4.1
4.3
6.32
7.03
mmol/l
1.28
32
217
22
119
1.85
1.96
1.0
1.1
1627.86
1519.28
miu/ml
0.15
22
119
29
171
1.70
1.96
1.7
1.6
31.76
33.70
%
0.09
16
108
124
975
1.28
1.91
8.6
4.1
1.16
1.23
%
0.34
124
968
121
951
1.28
1.88
8.7
4.1
0.65
0.66
%
0.07
121
945
12
52
2.31
1.87
1.3
1.2
—
—
—
0
0
34
213
1.60
1.84
2.3
2.5
—
—
—
0
0
35
221
1.59
1.84
1.1
1.1
—
—
—
0
0
121
1519
0.79
1.84
1.4
1.4
—
—
—
0
0
6
17
3.53
1.83
1.3
1.2
—
—
—
0
0
69
503
1.38
1.80
3.1
3.0
9.43
7.63
umol/l
0.25
57
391
59
421
1.41
1.75
1.4
1.6
0.58
0.80
g/l
1.29
44
325
15
74
2.03
1.74
1.4
1.3
—
—
—
0
0
79
593
1.34
1.73
1.3
1.4
66.00
80.74
titre
—
5
54
65
473
1.38
1.73
3.8
4.1
—
—
—
0
0
8
30
2.67
1.72
1.4
2.3
1.49
1.90
mg/l
—
8
24
19
103
1.85
1.71
2.3
2.7
1746.84
2027.93
ml
0.70
19
90
77
582
1.33
1.63
1.3
1.2
4.12
8.32
u/ml
—
6
60
21
120
1.75
1.61
3.7
2.8
320.33
181.66
umol/l
0.39
12
70
52
369
1.41
1.61
1.3
1.2
2.24
4.61
u/ml
1.71
25
164
195
1648
1.19
1.59
2.3
2.3
6.75
7.26
ug/l
0.10
174
1454
16
84
1.91
1.59
2.5
2.1
—
—
—
0
0
41
279
1.47
1.58
1.5
1.4
0.42
0.36
g/l
0.39
31
204
41
279
1.47
1.58
1.5
1.4
2.87
2.65
g/l
0.34
31
206
41
279
1.47
1.58
1.5
1.4
7.28
6.49
g/l
1.03
30
205
7
26
2.69
1.58
1.0
1.2
1.39
1.71
umol/24h
—
7
26
26
160
1.63
1.55
1.3
1.4
196.19
227.12
pmol/l
0.21
26
160
8
33
2.43
1.53
1.3
1.1
—
—
—
0
0
30
192
1.57
1.53
1.2
1.1
—
—
—
0
0
7
27
2.59
1.51
9.4
2.4
—
—
—
0
0
9
37
2.43
1.47
1.1
1.2
—
—
—
0
0
82
636
1.30
1.47
1.3
1.2
11.32
40.16
u/ml
—
5
36
9
38
2.37
1.45
1.6
1.3
—
—
—
0
0
15
80
1.88
1.44
1.0
1.2
—
—
—
0
0
54
395
1.37
1.43
2.2
1.8
68.66
65.15
mmol/l
0.25
44
325
244
2124
1.16
1.42
2.5
2.3
35.33
60.01
u/l
0.55
204
1807
43
303
1.42
1.41
1.7
1.8
—
—
—
0
0
27
173
1.56
1.39
3.8
4.0
—
—
—
0
0
27
174
1.56
1.36
1.2
1.5
—
—
—
0
0
22
135
1.63
1.35
1.1
1.1
1.05
1.05
ratio
—
6
58
9
42
2.14
1.33
2.3
1.4
—
—
—
0
0
852
8002
1.09
1.32
2.9
2.6
—
—
—
0
0
40
283
1.42
1.31
1.5
1.4
—
—
—
0
0
412
3737
1.12
1.30
3.7
2.9
4.24
2.73
e6/l
0.96
223
2016
139
1167
1.20
1.27
1.5
1.4
—
—
—
0
0
9
44
2.05
1.26
1.1
1.1
—
—
—
0
0
9
44
2.05
1.26
1.1
1.1
—
—
—
0
0
9
44
2.05
1.26
1.1
1.1
—
—
—
0
0
15
84
1.79
1.26
1.2
1.2
—
—
—
0
0
67
519
1.30
1.25
3.4
3.0
35.11
36.27
umol/l
0.14
62
476
5
116
0.43
1.25
1.0
1.1
—
—
—
0
0
265
2347
1.14
1.24
1.3
1.3
—
—
—
0
0
55
416
1.33
1.22
1.1
1.0
1.23
4.20
u/ml
2.25
19
174
27
180
1.50
1.20
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.5
1.3
98.50
152.62
mmol/l
—
6
21
15
86
1.75
1.18
4.2
4.1
—
—
—
0
0
50
376
1.33
1.16
1.6
1.6
—
—
—
0
0
108
896
1.21
1.14
1.3
1.8
1.47
1.47
g/l
0.01
89
778
16
95
1.69
1.13
3.1
1.7
—
—
—
0
0
183
1592
1.16
1.12
2.0
2.8
5.36
5.23
e9/l
0.05
150
1326
41
301
1.37
1.12
1.8
3.5
—
—
—
0
0
81
654
1.24
1.11
2.4
2.3
9.40
10.10
g/l
1.04
70
593
53
407
1.31
1.08
4.4
3.7
—
—
—
0
0
18
112
1.61
1.08
2.1
2.9
1955.44
1192.03
u/ml
0.26
18
112
146
1253
1.17
1.08
2.7
2.3
—
—
—
0
0
35
252
1.39
1.08
3.7
3.5
—
—
—
0
0
319
3506
0.90
1.06
1.5
1.5
—
—
—
0
0
104
869
1.20
1.04
1.1
1.1
—
—
—
0
0
24
162
1.48
1.03
1.2
1.4
147.38
78.81
umol/l
0.52
24
162
15
90
1.67
1.03
1.0
1.1
—
—
—
0
0
87
1050
0.82
1.03
2.2
1.9
—
—
—
0
0
19
122
1.56
1.02
1.4
1.3
132.37
134.58
nmol/l
0.08
19
122
21
139
1.51
0.99
1.3
1.2
—
—
—
0
0
97
810
1.20
0.99
5.5
4.8
—
—
—
0
0
90
750
1.20
0.95
2.3
2.0
5.79
1.91
ug/l
0.70
75
665
0
32
0.00
0.95
0.0
1.0
—
4.03
—
0
21
61
488
1.25
0.94
13.3
5.4
—
—
—
0
0
383
3529
1.10
0.93
1.9
1.7
—
—
—
0
0
43
329
1.31
0.93
1.6
1.4
6.60
6.99
mmol/l
0.50
37
295
6
27
2.22
0.93
1.7
2.8
—
—
—
0
0
16
101
1.59
0.93
1.1
1.2
—
—
—
0
0
41
312
1.32
0.92
2.5
2.5
—
—
—
0
0
20
134
1.49
0.91
1.5
1.2
—
—
—
0
0
116
995
1.17
0.90
1.3
1.3
242.07
232.66
miu/ml
0.09
49
494
85
710
1.20
0.89
2.1
1.5
253.45
237.31
u/ml
0.20
49
393
5
104
0.48
0.89
1.0
1.4
—
—
—
0
0
196
1749
1.13
0.88
4.0
3.4
—
—
—
0
0
38
290
1.31
0.85
1.2
1.2
—
—
—
0
0
27
195
1.39
0.85
1.3
1.2
—
—
—
0
0
57
459
1.25
0.85
1.2
1.2
—
—
—
0
0
35
457
0.76
0.84
1.2
1.1
22.00
1138.53
iu/ml
—
6
128
155
1367
1.14
0.84
1.3
1.2
—
—
—
0
0
6
31
1.94
0.84
3.7
6.1
37.30
28.87
ug/min
—
6
26
34
256
1.33
0.84
1.4
1.2
—
—
—
0
0
215
1938
1.12
0.82
1.5
1.4
—
—
—
0
0
230
2530
0.90
0.82
4.2
4.2
33.56
32.68
%
0.51
163
1759
14
213
0.65
0.81
3.2
2.7
—
—
—
0
0
20
138
1.45
0.81
1.1
1.0
—
—
—
0
0
20
139
1.44
0.78
2.9
2.6
45.33
42.06
%
0.37
15
73
916
8782
1.06
0.78
2.1
2.0
—
—
—
0
0
8
48
1.67
0.78
1.4
1.3
2.61
3.25
mmol/l
—
8
42
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
15
99
1.52
0.75
1.1
1.3
—
—
—
0
0
5
25
2.00
0.72
1.6
6.3
—
—
—
0
0
66
552
1.20
0.72
4.8
3.5
49.41
67.66
mg/l
0.58
43
450
66
552
1.20
0.72
4.8
3.5
26.62
46.59
mg/l
1.18
42
451
10
60
1.67
0.71
1.0
1.2
—
—
—
0
0
7
40
1.75
0.71
3.1
1.4
—
—
—
0
0
5
26
1.92
0.70
2.6
2.1
—
3.21
—
0
9
24
177
1.36
0.70
1.6
1.5
—
—
—
0
0
14
93
1.51
0.69
1.3
1.3
—
—
—
0
0
202
1838
1.10
0.68
1.4
1.4
—
—
—
0
0
763
7309
1.06
0.67
2.5
2.4
—
—
—
0
0
135
1202
1.13
0.67
3.7
1.9
—
—
—
0
0
20
144
1.39
0.67
1.1
1.0
—
—
—
0
0
106
931
1.14
0.65
1.2
1.2
—
—
—
0
0
12
78
1.54
0.65
10.8
13.0
—
—
—
0
0
5
29
1.72
0.63
1.0
1.3
177.82
133.05
ng/l
—
5
17
143
1284
1.12
0.63
1.8
1.4
—
—
—
0
0
16
112
1.43
0.63
1.6
7.7
70.18
73.57
mg/l
0.07
11
91
21
155
1.36
0.62
1.8
2.5
620.73
618.34
ml
0.01
11
105
12
176
0.68
0.62
3.4
2.1
—
—
—
0
0
17
121
1.41
0.62
1.1
1.2
—
—
—
0
0
11
71
1.55
0.61
3.8
8.2
1.20
1.21
mmol/l
0.14
11
66
10
63
1.59
0.61
4.0
6.3
—
—
—
0
0
41
334
1.23
0.60
1.6
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
0.11
—
0
10
8
51
1.57
0.60
1.8
1.3
—
—
—
0
0
8
51
1.57
0.60
1.8
1.3
—
—
—
0
0
8
51
1.57
0.60
1.8
1.3
—
—
—
0
0
27
209
1.29
0.60
26.4
8.4
11.23
11.22
%
0.00
27
209
13
184
0.70
0.57
1.0
1.0
—
—
—
0
0
18
132
1.36
0.56
1.2
1.0
—
—
—
0
0
47
392
1.20
0.56
1.1
1.1
—
—
—
0
0
26
330
0.79
0.56
1.8
1.7
—
—
—
0
0
109
973
1.12
0.55
1.1
1.1
—
—
—
0
0
6
37
1.62
0.55
1.3
1.2
—
—
—
0
0
10
148
0.67
0.55
1.4
1.3
200.91
15.88
u/ml
—
5
117
45
375
1.20
0.55
1.4
1.2
—
—
—
0
0
63
729
0.86
0.55
1.1
1.1
4.11
2.73
u/ml
0.40
40
463
16
116
1.38
0.54
2.5
3.1
—
84.06
—
0
18
26
205
1.27
0.52
2.6
2.5
1.09
1.56
g/24h
0.66
15
108
85
751
1.13
0.52
1.1
1.2
—
—
—
0
0
14
100
1.40
0.51
1.1
1.6
—
—
—
0
0
34
278
1.22
0.51
3.2
4.0
—
—
—
0
0
12
168
0.71
0.50
1.0
1.4
—
—
—
0
0
79
696
1.14
0.50
3.1
3.5
524.53
2123.27
u/ml
0.56
67
601
16
118
1.36
0.50
1.1
1.2
—
—
—
0
0
11
77
1.43
0.45
1.3
1.3
—
—
—
0
0
113
1027
1.10
0.45
2.5
2.4
—
—
—
0
0
17
219
0.77
0.44
1.2
1.2
—
—
—
0
0
6
91
0.66
0.42
1.3
1.4
160.50
160.94
mmol/24h
—
6
91
0
15
0.00
0.41
0.0
1.1
—
1.99
—
0
7
0
16
0.00
0.41
0.0
1.1
—
0.13
—
0
10
0
16
0.00
0.41
0.0
1.1
—
274.33
—
0
6
41
351
1.17
0.40
2.9
3.6
11.18
87.14
u/ml
0.93
41
344
178
1902
0.93
0.40
3.9
4.0
2.83
18.47
ug/l
2.77
137
1526
16
123
1.30
0.40
2.9
7.0
—
—
—
0
0
7
103
0.68
0.39
2.7
3.0
—
—
—
0
0
32
269
1.19
0.39
1.3
1.3
—
—
—
0
0
16
124
1.29
0.38
1.1
1.6
5.05
7.68
u/l
1.11
11
107
5
36
1.39
0.38
1.0
1.3
—
24.80
—
0
5
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
55
486
1.13
0.37
1.5
1.3
—
—
—
0
0
5
37
1.35
0.37
1.4
1.3
9.80
24.00
%
—
5
29
315
3005
1.05
0.37
3.1
2.9
0.69
0.73
ug/l
0.50
205
1921
47
534
0.88
0.36
1.4
1.9
0.82
0.74
nmol/l
0.35
42
454
127
1177
1.08
0.36
3.4
3.2
64.15
56.12
u/ml
0.10
122
1136
271
2578
1.06
0.35
1.9
1.7
—
—
—
0
0
39
338
1.15
0.35
1.8
1.8
—
—
—
0
0
9
126
0.71
0.35
1.4
1.1
133.44
217.53
iu/ml
—
9
126
17
211
0.80
0.34
1.0
1.4
3.69
4.31
u/ml
—
9
119
23
190
1.21
0.34
2.9
3.1
57.86
54.55
%
0.31
18
167
15
188
0.80
0.33
1.7
2.2
—
—
—
0
0
28
237
1.18
0.33
2.3
4.3
111.31
100.90
u/ml
0.06
12
71
6
89
0.67
0.33
4.2
2.6
—
—
—
0
0
55
492
1.12
0.32
1.2
1.1
—
—
—
0
0
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
77
841
0.91
0.32
1.3
1.2
0.97
3.06
u/ml
3.48
43
516
656
6385
1.03
0.31
7.1
7.0
—
—
—
0
0
81
742
1.09
0.31
1.2
1.2
—
—
—
0
0
55
494
1.11
0.30
1.2
1.1
—
—
—
0
0
7
54
1.30
0.30
4.3
2.6
—
—
—
0
0
7
54
1.30
0.30
8.6
5.3
—
—
—
0
0
164
1547
1.06
0.30
3.3
1.8
—
—
—
0
0
65
713
0.91
0.30
1.6
1.5
—
—
—
0
0
211
2008
1.05
0.29
4.1
4.0
—
—
—
0
0
42
373
1.13
0.28
1.2
1.6
—
—
—
0
0
162
1532
1.06
0.28
3.2
1.8
—
—
—
0
0
285
2737
1.04
0.28
1.3
1.3
—
—
—
0
0
8
62
1.29
0.28
1.1
1.3
16.39
17.62
umol/l
—
8
56
11
85
1.29
0.28
3.3
3.1
—
—
—
0
0
163
1544
1.06
0.27
3.2
1.8
—
—
—
0
0
44
394
1.12
0.27
1.1
1.0
—
—
—
0
0
20
168
1.19
0.27
1.6
1.5
0.92
0.98
g/l
0.36
20
168
23
267
0.86
0.26
1.7
1.4
—
—
—
0
0
151
1432
1.06
0.25
3.3
1.9
—
—
—
0
0
15
123
1.22
0.25
1.5
1.2
199.53
326.28
u/l
0.61
15
112
30
339
0.88
0.24
2.7
3.1
0.97
0.82
nmol/l
0.78
23
270
41
454
0.90
0.24
2.4
2.4
120.01
122.27
ug/min
0.01
18
280
6
81
0.74
0.24
1.0
1.2
—
0.10
—
0
7
123
1298
0.94
0.23
1.6
1.7
—
—
—
0
0
5
39
1.28
0.23
2.4
2.3
—
—
—
0
0
5
40
1.25
0.22
1.4
2.6
6.98
7.88
mmol/l
—
5
20
57
525
1.09
0.22
1.3
1.3
—
—
—
0
0
581
5684
1.03
0.21
2.4
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
1.88
—
0
6
0
12
0.00
0.21
0.0
2.9
—
—
—
0
0
65
697
0.93
0.20
1.6
1.5
—
—
—
0
0
10
80
1.25
0.20
2.4
2.3
—
209.56
—
0
11
0
14
0.00
0.20
0.0
1.1
—
0.07
—
0
8
6
49
1.22
0.20
1.2
1.7
—
—
—
0
0
92
868
1.06
0.20
1.7
1.6
—
—
—
0
0
65
695
0.93
0.19
1.6
1.5
—
—
—
0
0
16
186
0.86
0.19
1.1
1.2
—
—
—
0
0
15
127
1.18
0.19
1.9
2.4
505.20
498.03
min
—
10
90
32
353
0.90
0.19
3.7
3.8
22.97
31.53
u/ml
0.53
32
344
21
184
1.14
0.18
1.5
1.5
49908.18
127086.00
e6/l
0.89
11
111
22
194
1.13
0.18
1.5
1.4
14658.94
68337.57
e6/l
0.85
17
137
7
59
1.19
0.18
1.7
1.3
—
—
—
0
0
7
59
1.19
0.18
2.6
2.0
—
—
—
0
0
27
242
1.12
0.18
1.2
1.2
—
—
—
0
0
20
176
1.14
0.17
1.3
1.5
—
—
—
0
0
103
1077
0.95
0.16
3.7
3.1
—
—
—
0
0
8
70
1.14
0.16
4.6
2.3
—
—
—
0
0
44
408
1.08
0.16
1.2
1.2
—
—
—
0
0
59
554
1.07
0.15
1.2
1.2
—
—
—
0
0
158
1525
1.04
0.15
3.4
1.8
—
—
—
0
0
42
451
0.93
0.15
1.1
1.1
0.19
0.38
u/ml
0.51
18
172
9
80
1.12
0.15
1.1
1.9
—
—
—
0
0
51
543
0.94
0.15
1.3
1.5
86.58
190.63
pmol/l
1.87
46
531
8
97
0.82
0.13
2.6
2.4
—
—
—
0
0
756
7462
1.02
0.13
1.5
1.6
—
—
—
0
0
152
1471
1.03
0.13
2.9
2.8
—
—
—
0
0
27
247
1.09
0.13
1.3
1.2
—
—
nmol/l
—
0
0
17
189
0.90
0.12
1.7
1.6
—
—
—
0
0
19
172
1.10
0.11
1.5
1.4
—
—
—
0
0
17
188
0.90
0.11
1.2
1.3
134.88
23.57
u/ml
—
10
137
23
211
1.09
0.11
1.4
1.1
—
—
—
0
0
10
86
1.16
0.10
1.0
1.0
—
—
—
0
0
25
269
0.93
0.10
1.3
1.3
1.73
10.04
u/ml
0.97
12
132
23
212
1.08
0.10
1.6
1.5
9450.15
1783.82
e6/l
0.47
13
150
10
114
0.88
0.09
1.1
2.5
35.60
299.54
ug/l
—
10
100
5
46
1.09
0.09
1.4
2.2
—
—
—
0
0
33
310
1.06
0.09
1.3
1.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
14
155
0.90
0.09
1.1
1.0
20.51
19.57
mmol/l
0.52
14
146
67
694
0.96
0.08
9.0
9.2
—
—
—
0
0
13
144
0.90
0.08
1.0
1.0
—
—
—
0
0
72
743
0.97
0.08
1.2
1.1
0.47
1.27
u/ml
2.10
41
420
23
215
1.07
0.07
1.1
1.2
—
221.43
—
0
7
23
215
1.07
0.07
1.1
1.2
98.00
194.00
titre
—
5
45
8
77
1.04
0.07
1.6
1.4
—
—
—
0
0
24
225
1.07
0.07
1.1
1.1
0.42
2.96
u/ml
0.98
11
108
7
84
0.83
0.07
3.4
2.7
—
—
—
0
0
39
374
1.04
0.06
2.2
1.6
—
—
—
0
0
12
110
1.09
0.05
1.0
1.1
—
—
—
0
0
18
170
1.06
0.04
1.4
1.1
—
49.43
—
0
12
23
220
1.04
0.03
1.2
1.2
—
—
—
0
0
17
161
1.06
0.03
4.2
2.3
1.18
1.97
u/field
0.79
11
80
240
2380
1.01
0.03
1.3
1.3
—
—
—
0
0
46
469
0.98
0.02
3.8
3.4
21.05
24.93
mg/l
0.41
32
294
26
268
0.97
0.02
1.3
1.3
10.46
3.36
u/ml
0.39
11
153
49
497
0.98
0.01
1.1
1.1
14.66
8.63
u/ml
0.26
25
251
23
236
0.97
0.01
1.5
1.4
8.05
7.99
mmol/l
0.04
23
231
11
104
1.06
0.00
1.1
1.4
—
—
—
0
0
54
545
0.99
0.00
1.1
1.1
13.81
5.87
u/ml
0.64
31
310
18
181
0.99
0.00
3.9
2.0
—
—
—
0
0
22
225
0.98
0.00
1.1
1.1
—
—
—
0
0
10
95
1.05
0.00
1.3
1.1
—
—
—
0
0
50
501
1.00
0.00
1.7
1.7
11288.12
13084.31
e6/l
0.14
34
366
56
558
1.00
0.00
2.7
2.2
38.01
37.86
g/l
0.06
46
498
70
696
1.00
0.00
3.2
3.1
—
—
—
0
0
33
331
1.00
0.00
1.2
1.5
—
—
—
0
0
21
215
0.98
0.00
1.2
1.2
—
—
—
0
0
16
155
1.03
0.00
1.1
1.1
—
—
—
0
0
14
144
0.97
0.00
1.1
1.3
1.63
1.55
g/l
0.38
14
144
76
763
0.99
0.00
1.2
1.1
2.40
6.65
u/ml
4.22
49
480
10
97
1.03
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
5
49
1.02
0.00
2.8
4.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
-0.00
1.5
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.5
1.4
49.48
53.07
%
—
6
54
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.88
-0.00
1.4
1.4
61.14
88.33
nmol/24h
—
7
79
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
525.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.7
—
—
—
0
0
5
55
0.91
-0.00
1.8
1.2
—
—
—
0
0
5
58
0.86
-0.00
1.6
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_HYPERMETRO and mortality.

Females

Parameter HR [95% CI] p-value
H7_HYPERMETRO 1.047 [0.92, 1.2] 0.5
Birth year 0.994 [0.99, 1.0] 0.16

During the follow-up period (1.1.1998 — 31.12.2019), 1035 out of 19706 females with H7_HYPERMETRO died.

Males

Parameter HR [95% CI] p-value
H7_HYPERMETRO 1.28 [1.1, 1.49] 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 874 out of 16671 males with H7_HYPERMETRO died.

Mortality risk

Mortality risk for people of age

years, who have H7_HYPERMETRO.

N-year risk Females Males
1 0.108% 0.214%
5 0.595% 1.629%
10 1.473% 3.821%
15 2.768% 7.326%
20 4.922% 12.191%

Relationships between endpoints

Index endpoint: H7_HYPERMETRO – Hypermetropia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data