obsolete_hyperopia:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2837 |
4. Check minimum number of eventsNone |
2837 |
5. Include endpointsNone |
2837 |
6. Filter based on genotype QC (FinnGen only) |
2837 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H52
- Name in latin
- Hyperopia
Similar endpoints
↥List of similar endpoints to
Hypermetropia
based on the number of shared cases.
Similar with more cases:
- Disorders of refraction and accommodation
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 43985 | 23830 | 20105 |
| Only index persons | 33198 | 18331 | 14867 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.63 | 0.68 | 0.56 |
| Only index persons | 0.63 | 0.67 | 0.57 |
| Median age at first event (years) | |||
| Whole population | 7.22 | 7.69 | 6.59 |
| Only index persons | 9.13 | 10.16 | 7.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2837 | 1813 | 1024 |
| Unadjusted period prevalence (%) | 0.56 | 0.62 | 0.45 |
| Median age at first event (years) | 49.27 | 47.26 | 52.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2454
- Matched controls
- 24528
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.0
ICD-10 Finland
Hypermetropia
8196.4
323.0
2320
41
H52.2
ICD-10 Finland
Astigmatism
112.8
292.2
315
32
H53.0
ICD-10 Finland
Amblyopia ex anopsia
47.5
157.5
193
44
H52.4
ICD-10 Finland
Presbyopia
24.3
149.6
216
97
H50.0
ICD-10 Finland
Convergent concomitant strabismus
1325.6
130.4
126
*
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
115.5
110
*
H50.30
ICD-10 Finland
Intermittent esotropy
491.2
96.0
95
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
108.5
86.5
94
9
H50.31
ICD-10 Finland
Intermittent exotropia
356.9
69.9
70
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
61.7
59
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
570.6
56.8
56
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
56.5
507
2286
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
+∞
53.3
51
*
H50.52
ICD-10 Finland
Exophoria
56.8
51.8
61
11
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
260.5
50.2
51
*
H50.2
ICD-10 Finland
Vertical strabismus
218.6
42.0
43
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
41.8
868
5526
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.8
41.0
298
1173
XCK00
NOMESCO Finland
Perimetry
3.4
38.9
199
616
CHC05
NOMESCO Finland
Iridotomy
8.1
38.6
89
114
H50.51
ICD-10 Finland
Esophoria
135.4
37.8
40
*
H40.0
ICD-10 Finland
Glaucoma suspect
3.3
37.8
205
663
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.0
34.9
555
3164
H53.1
ICD-10 Finland
Subjective visual disturbances
3.1
30.9
177
594
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.8
30.8
679
4312
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
30.3
29
*
R51.80
ICD-10 Finland
Headache
2.0
30.1
423
2283
H25.0
ICD-10 Finland
Senile incipient cataract
3.4
29.4
150
463
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
29.2
28
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.7
26.0
76
137
ZXA10
NOMESCO Finland
Bilateral
1.9
25.9
438
2523
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
24.0
23
*
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
87.6
23.7
26
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
22.1
237
1133
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
20.5
862
6379
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
20.1
204
951
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
18.3
426
2694
H53.2
ICD-10 Finland
Diplopia
4.1
18.0
71
178
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
17.9
189
896
CHD00
NOMESCO Finland
Laser trabeculoplasty
6.7
17.8
45
68
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.1
17.7
201
982
H52.1
ICD-10 Finland
Myopia
4.6
17.5
61
136
H54.7
ICD-10 Finland
Unspecified visual loss
8.3
17.0
37
45
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
16.7
16
*
UDC00
NOMESCO Finland
Ear microscopy
2.1
16.2
184
899
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
16.2
206
1059
F83
ICD-10 Finland
Mixed specific developmental disorders
4.1
16.2
63
157
SPAT1301
SPAT
No procedures
1.5
15.9
712
5279
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
15.8
447
2973
WX110
NOMESCO Finland
Local anesthesy
1.4
15.7
1610
13993
XCK10
NOMESCO Finland
Photography of fundus of eye
2.0
15.6
205
1064
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
38.3
15.4
19
5
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.1
15.4
180
892
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
14.9
594
4279
A02BC05
ATC
esomeprazole; systemic
1.5
14.6
756
5753
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
14.6
14
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
14.6
14
*
AA1AD
NOMESCO Finland
CT of head and brain
1.6
14.5
421
2812
N02BE01
ATC
paracetamol; systemic, rectal
1.4
14.2
1815
16263
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
7.7
14.1
32
42
XA800
NOMESCO Finland
Neuropsychological investigation
2.4
14.1
117
495
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
14.0
174
884
R62.0
ICD-10 Finland
Delayed milestone
3.8
13.7
57
152
3503
FHL
Single muscle retroposition
+∞
13.5
13
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
13.5
223
1261
H50.9
ICD-10 Finland
Strabismus, unspecified
16.3
13.4
21
13
R42
ICD-10 Finland
Dizziness and giddiness
1.6
13.4
405
2729
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
13.3
384
2559
SPAT1263
SPAT
Sampling
1.4
13.3
952
7661
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
13.0
625
4668
H52.5
ICD-10 Finland
Disorders of accommodation
50.2
12.8
15
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
12.7
482
3423
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
130.6
12.4
13
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
12.3
302
1924
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
12.3
580
4305
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
12.0
310
2001
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
13.4
11.9
20
15
P85
ICPC
Mental retardation
7.6
11.9
27
36
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
11.8
257
1585
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.5
753
5926
G44.2
ICD-10 Finland
Tension-type headache
1.7
11.5
271
1709
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
11.4
1140
9609
M54.5
ICD-10 Finland
Low back pain
1.4
11.4
632
4827
L04AD01
ATC
ciclosporin; systemic
3.3
11.4
56
172
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
11.4
122
585
WX400
NOMESCO Finland
Inhalation anesthesy
2.1
11.2
123
594
G47.3
ICD-10 Finland
Sleep apnoea
1.5
11.2
357
2431
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
11.0
323
2156
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
10.9
521
3867
N03AX12
ATC
gabapentin; oral
1.6
10.7
274
1766
WX720
NOMESCO Finland
Own respiration
2.5
10.7
85
351
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.9
10.6
162
892
CEC30
NOMESCO Finland
Resection of extraocular muscle
110.4
10.4
11
*
WX702
NOMESCO Finland
Supraglottic ventilation device
2.1
10.3
110
527
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.3
452
3294
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.8
10.2
174
994
TAB00
NOMESCO Finland
Lumbar puncture
2.2
10.2
101
467
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
10.2
747
5968
J05AB01
ATC
aciclovir; systemic
1.5
10.1
382
2695
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
10.1
961
7994
L03
ICPC
Low back symptom/complaint
1.4
10.0
497
3706
37929
ICD-8 Finland
Blindness, one eye, specifically defined
40.2
10.0
12
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.5
9.9
77
317
H02AB06
ATC
prednisolone; systemic
1.3
9.8
878
7224
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.7
446
3277
C07AA05
ATC
propranolol; systemic
1.5
9.6
380
2704
N05CF01
ATC
zopiclone; oral
1.4
9.6
545
4163
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
9.5
197
1198
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
9.5
1047
8871
J01DB01
ATC
cefalexin; oral
1.3
9.4
1793
16413
Z31.5
ICD-10 Finland
Genetic counselling
2.0
9.4
119
612
3507
FHL
Retroposition and resection
+∞
9.4
9
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.9
9.3
37
97
H47.2
ICD-10 Finland
Optic atrophy
9.5
9.3
18
19
SPAT1310
SPAT
Counselling related to known health issue
1.3
9.2
712
5715
S06.0
ICD-10 Finland
Concussion
1.6
9.2
231
1481
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
9.2
167
976
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.5
9.2
26
48
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
9.1
129
694
H26.4
ICD-10 Finland
After-cataract
1.8
9.1
144
805
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.0
9.1
52
178
L17
ICPC
Foot/toe symptom/complaint
1.4
9.1
539
4144
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
5.9
9.0
24
41
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
9.0
734
5936
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
9.0
391
2835
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.0
9.0
111
567
XKC03
NOMESCO Finland
Water cystometry
2.5
8.8
64
255
L08
ICPC
Shoulder symptom/complaint
1.5
8.8
345
2453
XCH00
NOMESCO Finland
Eye pressure measurement
2.3
8.8
76
332
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
8.7
169
1006
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.8
8.7
35
93
602
Kela drug reimbursment
Children's severe malnutrition
3.6
8.6
37
104
H02AB09
ATC
hydrocortisone; systemic
2.4
8.6
69
290
WX704
NOMESCO Finland
Intubation
1.8
8.6
143
814
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.8
8.5
52
188
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
8.5
637
5079
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.5
813
6726
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.1
8.4
44
144
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
90.3
8.4
9
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
8.4
186
1151
N06AX16
ATC
venlafaxine; oral
1.5
8.4
258
1738
SPAT1153
SPAT
Removal of sutures
1.4
8.4
564
4424
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
8.3
8
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
8.3
8
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
8.3
8
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.9
8.3
126
694
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
10.8
8.3
15
14
127
Kela drug reimbursment
Transplant complication
3.0
8.3
44
146
A02BC02
ATC
pantoprazole; systemic
1.3
8.2
1193
10415
Z94.0
ICD-10 Finland
Kidney transplant status
3.6
8.2
35
98
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.2
916
7725
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
14.5
8.2
13
9
B03XA01
ATC
erythropoietin; parenteral
4.5
8.2
27
60
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.3
8.2
72
318
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
8.1
255
1724
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
8.1
439
3318
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
8.1
8.1
17
21
B34.9
ICD-10 Finland
Viral infection, unspecified
2.1
8.1
89
435
G91.1
ICD-10 Finland
Obstructive hydrocephalus
10.0
8.0
15
15
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
8.0
164
996
A11CC03
ATC
alfacalcidol; systemic
2.8
8.0
49
179
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
8.0
431
3254
M03BX02
ATC
tizanidine; oral
1.3
8.0
1137
9893
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
2.1
7.9
83
396
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
7.9
269
1856
Z99.2
ICD-10 Finland
Dependence on renal dialysis
10.8
7.8
14
13
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
7.7
256
1752
H57.1
ICD-10 Finland
Ocular pain
2.3
7.7
69
307
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.7
1590
14465
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
7.7
117
646
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
7.7
171
1062
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
2.6
7.7
54
213
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.3
7.7
22
42
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.4
7.6
26
60
M25.5
ICD-10 Finland
Pain in joint
1.3
7.6
534
4208
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
7.6
240
1628
L04AA06
ATC
mycophenolic acid; systemic
2.9
7.6
44
154
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.3
7.6
63
272
H66.9
ICD-10 Finland
Otitis media, unspecified
1.6
7.5
207
1357
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
7.5
132
764
N06AA09
ATC
amitriptyline; systemic
1.7
7.5
166
1032
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
7.5
532
4200
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.9
7.4
43
150
H50.8
ICD-10 Finland
Other specified strabismus
80.3
7.4
8
*
R35
ICD-10 Finland
Polyuria
1.9
7.4
103
551
E0000UV
ATC
NA
1.3
7.4
860
7270
R03AC02
ATC
salbutamol; inhalant
1.3
7.4
1109
9678
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.4
7.3
61
263
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.3
7.3
66
294
M79.6
ICD-10 Finland
Pain in limb
1.3
7.3
670
5484
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.4
7.3
33
98
3504
FHL
Retroposition of two muscles
+∞
7.3
7
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
7.3
7
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
7.3
7
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
7.3
165
1029
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
7.2
106
580
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
7.2
679
5576
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.2
7.2
73
343
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.6
7.2
48
185
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.5
7.2
221
1491
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
7.2
307
2220
R11
ICD-10 Finland
Nausea and vomiting
1.6
7.1
176
1126
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
12.0
7.1
12
10
BE00A
NOMESCO Finland
NA
12.0
7.1
12
10
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.8
7.0
112
631
NF1DA
NOMESCO Finland
X-ray of hips
2.8
7.0
43
158
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
3.5
7.0
30
86
R06.5
ICD-10 Finland
Mouth breathing
1.6
7.0
159
996
K30
ICD-10 Finland
Functional dyspepsia
1.6
6.9
176
1135
RT150
NOMESCO Finland
NA
4.6
6.9
22
48
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
3.2
6.9
33
103
A02BC03
ATC
lansoprazole; oral
1.3
6.9
467
3656
137
Kela drug reimbursment
Uraemia requiring dialysis
4.1
6.9
25
62
N07BA03
ATC
varenicline; oral
2.0
6.9
85
439
D06
ICPC
Abdominal pain localized other
1.6
6.8
180
1171
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
4.8
6.8
21
44
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
6.8
44
165
J02AC01
ATC
fluconazole; systemic
1.3
6.8
719
5986
WX725
NOMESCO Finland
Noninvasive ventilation
1.9
6.8
88
459
SPAT1325
SPAT
Vaccination
1.3
6.8
739
6175
RL140
NOMESCO Finland
NA
5.0
6.8
20
40
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.1
6.8
77
381
SPAT1009
SPAT
Measurement of intraocular pressure
3.3
6.8
32
99
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
40.1
6.8
8
*
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.0
6.7
79
396
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.6
6.7
45
174
K59.0
ICD-10 Finland
Constipation
1.8
6.7
104
581
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.7
237
1644
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.7
639
5245
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
6.7
92
493
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.1
6.6
33
106
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
6.6
280
2019
H01AC01
ATC
somatropin; parenteral
3.1
6.6
34
112
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
6.6
350
2632
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
6.6
231
1607
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
6.5
158
1007
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
10.0
6.5
12
12
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
10.0
6.5
12
12
B05DA
ATC
Isotonic solutions
4.5
6.5
21
47
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.4
152
962
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.7
6.4
42
160
N06AX11
ATC
mirtazapine; oral
1.3
6.4
559
4535
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.7
6.4
120
711
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.4
411
3189
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.7
6.3
125
752
114
Kela drug reimbursment
Glaucoma
1.7
6.3
130
791
A02BC01
ATC
omeprazole; systemic
1.3
6.3
468
3707
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.6
6.3
165
1071
N05BA01
ATC
diazepam; systemic, rectal
1.5
6.3
225
1566
H53.3
ICD-10 Finland
Other disorders of binocular vision
6.0
6.3
16
27
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
6.0
6.3
16
27
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.1
6.3
67
326
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.3
943
8176
S01ED51
ATC
timolol, combinations; ophthalmic
1.7
6.3
112
654
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
6.3
71
353
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.3
372
2848
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
6.2
6
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.2
257
1844
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
2.0
6.2
71
355
KMAK
NOMESCO Finland
NA
1.2
6.2
970
8451
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
6.2
174
1149
K07.60
ICD-10 Finland
Snapping jaw
1.8
6.1
95
532
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.1
667
5563
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
7.7
6.1
13
17
C09CA06
ATC
candesartan; oral
1.4
6.1
337
2549
P07.2
ICD-10 Finland
Extreme immaturity
12.5
6.1
10
8
UJF32
NOMESCO Finland
Coloscopy
1.3
6.1
414
3239
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.0
6.1
32
108
XF602
NOMESCO Finland
Bloodpressure monitoring
3.3
6.1
28
86
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.0
1525
13982
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.4
6.0
20
46
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.0
125
763
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.0
626
5191
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.9
6.0
84
454
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1938
16435
1.56
25.86
7.8
7.0
80.0
81.6
u/l
0.73
1830
15462
1164
8918
1.52
24.53
5.9
5.0
36.2
36.0
g/l
0.58
1085
8278
1340
10606
1.50
23.94
9.0
7.0
1.2
1.2
mmol/l
0.26
1095
9038
1920
16523
1.50
21.54
4.8
4.0
10.7
11.1
mm/h
0.73
1781
15319
1765
14997
1.47
20.61
5.9
4.2
3968.9
1838.7
e6/l
0.29
20
186
1222
9720
1.45
20.03
8.2
6.6
1.2
1.2
mmol/l
0.72
1097
8846
803
5901
1.50
19.63
2.2
2.1
168.6
223.0
u/l
1.72
757
5544
2044
17954
1.49
19.57
4.7
3.9
14.6
14.7
pmol/l
0.52
1864
16322
1538
12822
1.43
19.24
5.7
4.9
6.3
6.5
mmol/l
3.46
1416
11862
1325
10808
1.42
18.37
6.0
6.2
11.7
11.9
umol/l
0.12
1250
10168
2317
21036
1.55
17.67
5.4
4.6
1.9
2.0
mu/l
0.65
2142
19431
356
2212
1.70
17.62
2.7
2.2
364.0
369.8
nmol/l
0.19
327
2026
1348
11110
1.41
17.20
4.5
3.5
0.0
0.0
estimate
0.00
278
2116
857
6523
1.45
17.05
2.7
2.5
57.9
56.4
u/l
0.32
801
6010
23
30
7.72
16.55
6.4
6.3
—
—
—
0
0
23
30
7.72
16.55
6.9
6.8
—
—
—
0
0
1353
11224
1.39
16.27
4.5
3.5
0.0
0.0
estimate
0.25
281
2103
1342
11131
1.39
16.09
6.0
4.8
0.0
0.0
estimate
0.41
289
2161
21
26
8.13
15.76
7.9
9.0
—
—
—
0
0
2492
23260
1.58
14.07
15.8
12.6
21.5
22.8
mg/l
1.19
1979
17808
1135
9316
1.36
13.80
3.0
2.4
75.5
74.7
nmol/l
0.38
1031
8451
1428
12169
1.35
13.47
7.7
6.6
0.2
0.2
e9/l
0.32
1267
10638
2556
24059
1.63
13.25
17.3
14.0
73.8
72.6
umol/l
0.98
2556
24050
483
3443
1.48
13.03
1.9
1.7
1209.2
1177.9
nmol/l
0.31
364
2603
105
480
2.23
13.02
3.9
3.7
55.4
56.1
%
0.22
105
480
2466
23042
1.53
12.98
17.6
14.3
4.0
3.9
mmol/l
0.46
2410
22331
2462
22999
1.53
12.95
17.6
14.1
139.7
139.6
mmol/l
0.75
2407
22343
1040
8482
1.36
12.94
4.7
3.6
—
—
—
0
0
127
631
2.06
12.74
1.7
1.9
379.3
504.6
mg/l
3.99
119
598
264
1650
1.66
12.67
5.6
3.9
1.2
1.2
mmol/l
0.87
219
1424
27
56
4.86
12.36
11.3
7.7
—
—
—
0
0
521
3814
1.45
12.18
3.8
3.6
139.6
466.7
ng/l
6.03
366
2725
2727
26237
2.01
11.80
22.8
18.4
6.7
6.7
e9/l
0.56
2662
25396
431
3062
1.48
11.74
9.9
6.8
1.1
1.1
mmol/l
0.69
403
2849
2726
26239
1.98
11.54
22.9
18.5
134.5
134.8
g/l
0.57
2695
25861
115
572
2.05
11.53
1.6
1.9
3.5
3.7
mmol/l
1.47
107
540
2725
26228
1.98
11.51
22.8
18.3
4.5
4.5
e12/l
0.52
2659
25379
2550
24113
1.56
11.50
11.3
9.6
26.2
25.7
u/l
0.23
2465
23270
896
7243
1.35
11.48
3.6
3.4
299.5
51.5
ng/l
0.47
525
4545
2093
19103
1.36
11.46
5.4
5.1
38.3
38.9
mmol/mol
2.40
1941
17767
115
576
2.04
11.32
1.8
2.1
8.5
26.9
e6/l
0.96
82
432
115
577
2.03
11.27
1.8
2.2
1544.7
1205.4
e6/l
0.12
89
457
1406
12146
1.31
11.21
7.4
6.3
2.0
2.0
e9/l
0.80
1250
10677
2722
26211
1.94
11.15
22.8
18.4
256.2
256.7
e9/l
0.15
2661
25430
55
200
2.78
11.12
1.1
1.1
207.5
249.4
mg/l
0.99
44
170
877
7097
1.34
11.08
3.7
3.2
2.4
2.4
mmol/l
1.03
784
6236
1542
13505
1.31
11.05
10.0
9.0
3.9
4.0
e9/l
0.56
1367
11737
56
207
2.74
10.99
1.2
1.2
28.5
38.1
mg/l
1.35
41
166
990
8187
1.32
10.67
2.0
1.9
97.7
95.3
pmol/l
0.86
501
4290
605
4644
1.38
10.66
4.0
2.6
6.9
6.8
e6/l
0.02
540
4068
132
710
1.90
10.60
5.0
5.6
1.8
1.6
%
0.69
121
654
884
7210
1.33
10.45
3.9
3.3
34.0
34.5
u/l
0.04
834
6848
1294
11122
1.30
10.42
7.7
6.4
3.0
2.9
%
0.48
1225
10403
743
5941
1.34
9.99
5.3
3.8
0.0
0.0
estimate
1.28
276
2094
647
5071
1.36
9.92
3.4
2.7
2837.4
5038.3
umol/l
0.94
553
4443
694
5508
1.34
9.78
1.8
1.7
1.3
1.4
mmol/l
0.18
591
4698
1338
11613
1.29
9.76
7.7
6.4
29.7
29.8
%
0.14
1266
10888
88
423
2.11
9.71
3.4
2.7
16.3
16.5
%
0.20
53
215
1317
11427
1.28
9.56
7.4
6.2
55.4
55.4
%
0.04
1241
10749
158
939
1.72
9.17
1.9
1.7
9.1
8.0
u/l
0.55
122
709
444
3314
1.40
9.12
1.8
1.8
—
—
—
0
0
710
5716
1.32
8.95
2.3
2.4
2.9
2.9
mg/l
0.09
602
4893
757
6162
1.31
8.79
1.5
1.4
1.9
2.0
u/ml
0.08
193
1498
35
113
3.12
8.78
1.6
1.3
75.7
71.4
%
—
6
13
104
553
1.91
8.71
9.1
4.4
23.6
24.5
mmol/l
1.10
98
495
448
3379
1.39
8.63
6.0
4.8
0.8
0.8
mmol/l
0.11
414
3179
582
4592
1.34
8.37
1.6
1.5
20.0
20.6
nmol/l
0.59
494
3937
54
228
2.39
8.17
2.0
1.5
—
—
—
0
0
1636
14741
1.26
8.08
3.5
3.2
43.3
43.2
u/l
0.01
1521
13849
298
2114
1.46
8.08
4.1
3.1
—
—
—
0
0
481
3707
1.36
8.06
1.3
1.3
36.0
33.0
iu/ml
0.12
136
1096
49
199
2.49
8.06
1.1
1.1
—
—
—
0
0
2349
22173
1.34
7.89
16.7
13.7
39.4
39.7
%
1.05
1632
17000
232
1575
1.51
7.83
3.3
3.2
155.8
187.2
ng/l
0.93
216
1420
433
3300
1.37
7.78
3.3
2.4
12.9
13.5
umol/l
0.90
401
3057
1222
10680
1.25
7.77
3.4
2.8
99.8
99.0
ug/l
0.05
1130
9946
2155
20123
1.29
7.67
19.3
15.4
13.5
13.5
%
0.12
2123
19687
430
3283
1.36
7.63
2.4
3.0
29.4
29.9
s
1.32
420
3195
263
1843
1.47
7.60
2.9
3.0
9.8
10.2
g/l
0.87
243
1694
140
850
1.68
7.56
16.4
10.1
1.5
1.3
mg/l
2.20
129
806
234
1607
1.50
7.47
5.9
4.4
78.3
78.0
ng/l
0.02
209
1426
2204
20662
1.30
7.47
4.4
4.0
5.7
5.8
mmol/l
2.40
1999
18880
169
1080
1.60
7.46
10.7
6.1
9.2
9.3
kpa
0.21
164
1016
317
2313
1.42
7.37
1.7
1.8
—
—
—
0
0
314
2297
1.41
7.19
1.7
1.8
—
—
—
0
0
397
3021
1.36
7.18
3.3
2.4
2.4
2.4
g/l
0.43
368
2794
69
341
2.05
7.17
2.4
2.1
1.6
1.7
mmol/l
0.36
69
336
138
848
1.66
7.14
2.1
1.9
40.8
39.6
u/l
0.28
124
762
173
1131
1.56
6.95
6.9
6.9
24.3
24.4
mmol/l
0.16
160
1050
590
4777
1.30
6.92
2.0
2.2
1.1
1.2
mg/l
0.61
435
3543
223
1546
1.48
6.81
2.5
2.2
10.8
11.6
nmol/l
0.72
196
1347
276
1993
1.43
6.80
14.0
8.7
8.1
8.2
mmol/l
0.11
268
1914
36
137
2.65
6.80
1.1
1.1
1.0
1.1
u/l
0.38
14
64
369
2799
1.37
6.80
3.4
2.5
21.7
22.9
%
0.90
301
2424
29
99
2.95
6.69
1.1
1.1
—
—
—
0
0
605
4935
1.29
6.67
4.4
3.7
1.0
1.0
kg/l
0.83
100
755
158
1025
1.57
6.57
9.0
10.7
—
—
—
0
0
206
1421
1.48
6.46
1.3
1.3
18.1
55.7
au/ml
—
5
57
448
3527
1.32
6.42
1.3
1.2
6.5
10.8
u/ml
0.86
155
1366
251
1803
1.43
6.37
1.2
1.2
124.7
153.8
iu/ml
0.64
96
645
243
1740
1.43
6.28
1.4
1.3
271.2
231.3
u/ml
0.31
217
1614
129
807
1.63
6.26
1.3
1.2
0.3
0.8
u/ml
—
9
61
206
1436
1.47
6.14
2.8
2.3
10900.9
6336.3
u/l
0.70
60
528
205
1429
1.47
6.11
3.3
3.2
4.6
4.6
pmol/l
0.35
185
1265
241
1735
1.42
6.05
7.5
8.3
122.1
122.2
g/l
0.03
230
1669
220
1560
1.44
6.00
2.4
2.3
22.3
21.7
au/ml
—
6
86
620
5144
1.26
5.88
3.1
3.2
1078.0
1249.7
ng/l
0.71
516
4311
1184
10533
1.21
5.79
4.2
4.0
—
—
—
0
0
512
4162
1.28
5.73
1.8
1.6
435.6
28884835.5
pmol/l
3.49
418
3469
84
480
1.77
5.71
2.9
2.4
127.1
131.5
g/l
1.02
71
367
52
253
2.07
5.70
1.1
1.0
—
—
—
0
0
448
3587
1.30
5.64
3.2
2.9
2.5
2.4
mmol/l
0.28
392
3124
313
2383
1.35
5.62
7.5
5.6
5.9
5.8
kpa
0.45
301
2305
312
2375
1.35
5.61
7.5
5.6
1.8
1.7
mmol/l
0.24
255
1889
2214
20994
1.25
5.47
4.5
4.0
4.6
4.6
mmol/l
0.29
2037
19559
49
240
2.06
5.30
3.0
2.7
—
—
—
0
0
50
247
2.04
5.29
2.9
2.7
14.0
10.5
%
1.32
33
168
90
543
1.68
5.09
2.1
1.8
—
—
—
0
0
24
87
2.77
5.03
1.3
1.2
—
—
—
0
0
409
3289
1.28
4.96
2.1
2.6
87.4
117.9
ug/g
2.46
324
2580
313
2429
1.32
4.95
3.8
3.4
1.5
1.7
%
4.62
272
2180
112
720
1.58
4.93
1.1
1.1
4.6
8.8
u/ml
—
10
97
724
6219
1.22
4.89
4.4
3.1
0.3
0.4
e6/l
0.46
566
4668
2234
21283
1.23
4.84
4.9
4.4
2.7
2.8
mmol/l
0.24
2054
19679
281
2154
1.34
4.84
7.1
7.8
0.9
1.0
mmol/l
0.10
213
1669
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
35
156
2.26
4.82
1.2
1.1
—
—
—
0
0
14
37
3.80
4.81
1.1
1.2
0.6
0.7
umol/24h
—
7
24
757
6548
1.21
4.74
4.0
3.3
7.3
7.8
mmol/l
2.31
651
5604
98
617
1.61
4.72
1.3
1.4
289.5
305.5
ug/g
0.31
55
353
281
2163
1.33
4.70
7.1
7.8
5.1
5.1
kpa
0.13
265
2063
157
1101
1.45
4.60
1.8
1.6
293.5
312.7
mu/l
0.40
139
985
280
2163
1.33
4.58
7.1
7.7
13.0
12.8
kpa
0.32
264
2065
166
1179
1.43
4.55
1.9
1.6
23.9
21.9
iu/l
0.30
129
931
97
617
1.59
4.49
1.8
1.7
40.1
39.4
nmol/l
0.06
97
598
204
1507
1.38
4.46
3.2
2.7
66.1
66.4
g/l
0.26
183
1387
66
380
1.75
4.45
1.4
1.5
—
—
—
0
0
199
1468
1.38
4.40
1.6
1.6
—
—
—
0
0
139
962
1.47
4.37
2.1
1.9
—
—
—
0
0
2184
20828
1.21
4.31
4.4
4.0
1.5
1.5
mmol/l
0.04
2004
19294
34
159
2.15
4.21
1.2
1.2
—
—
—
0
0
266
2066
1.32
4.20
7.6
5.4
4.9
4.8
kpa
0.32
256
1998
314
2496
1.29
4.17
3.2
3.5
5.3
7.4
umol/l
3.78
255
2144
34
161
2.12
4.09
1.2
1.2
—
—
—
0
0
78
485
1.62
4.00
9.5
6.3
2120.6
657.2
iu/ml
0.32
14
62
2103
20049
1.19
3.87
4.0
3.6
1.3
1.3
mmol/l
0.17
1929
18491
286
2270
1.29
3.86
4.6
4.5
258.5
248.7
u/l
0.27
272
2152
230
1777
1.32
3.79
9.4
5.6
1.4
1.4
mmol/l
0.05
170
1290
25
108
2.33
3.75
1.1
1.1
0.4
2.8
nmol/l
—
5
22
236
1833
1.31
3.75
9.3
5.6
5.0
5.1
kpa
0.76
228
1731
106
720
1.49
3.71
1.7
1.6
372.5
205.6
titre
—
8
25
51
289
1.78
3.69
1.4
1.5
—
—
—
0
0
474
4007
1.22
3.68
1.5
1.5
—
—
—
0
0
42
226
1.87
3.59
1.2
1.5
6.1
5.1
umol/l
0.72
42
204
54
315
1.73
3.55
1.6
1.3
—
—
—
0
0
53
310
1.72
3.46
1.5
1.5
—
—
—
0
0
65
402
1.63
3.45
10.3
5.0
85.0
786.9
u/ml
—
6
32
654
5731
1.18
3.42
4.1
4.0
14.1
12.4
mg/mmol
0.17
403
3659
204
1580
1.31
3.33
8.0
6.2
23.8
23.9
mmol/l
0.21
188
1480
41
225
1.83
3.32
1.7
1.6
52.1
59.8
%
0.53
23
150
42
233
1.81
3.29
2.8
2.7
537.5
565.2
e6/l
0.11
33
184
70
448
1.58
3.25
1.2
1.2
61.0
43.2
u/ml
—
5
38
100
692
1.46
3.23
2.0
1.7
0.2
0.2
g/l
0.12
88
655
79
525
1.52
3.12
2.1
2.1
10.3
11.2
mg/l
0.48
71
484
27
131
2.07
3.12
1.9
1.6
—
—
—
0
0
64
407
1.59
3.07
1.7
1.5
0.3
0.4
nmol/l
0.57
57
317
16
62
2.59
3.04
2.6
2.2
20.7
17.1
umol/l
0.39
16
62
1827
17357
1.15
3.04
3.4
3.4
—
—
—
0
0
14
51
2.75
2.98
5.0
5.2
—
—
—
0
0
18
75
2.41
2.96
1.3
1.2
—
—
—
0
0
101
714
1.43
2.95
2.0
1.7
1.1
1.2
g/l
0.79
89
678
258
2099
1.25
2.88
2.7
2.8
0.2
0.2
g/l
0.12
243
1962
440
3779
1.19
2.88
3.5
2.7
0.8
1.2
e6/l
1.89
259
2121
40
229
1.76
2.87
2.9
2.8
0.3
0.2
e9/l
0.68
33
184
109
787
1.40
2.84
1.4
1.3
—
—
—
0
0
68
448
1.53
2.83
1.2
1.3
—
—
—
0
0
52
323
1.62
2.78
3.5
3.5
1.5
1.2
%
0.22
41
262
81
556
1.47
2.78
1.6
1.7
—
—
—
0
0
9
23
3.92
2.77
1.0
1.0
—
—
—
0
0
28
145
1.94
2.74
1.2
1.1
—
—
—
0
0
101
727
1.40
2.69
1.6
1.6
116.7
0.2
iu/ml
0.48
18
147
11
37
2.98
2.69
1.3
2.2
—
—
—
0
0
11
37
2.98
2.69
1.3
1.2
—
—
—
0
0
451
3912
1.18
2.64
4.7
4.0
21.2
21.1
%
0.03
204
1817
52
328
1.60
2.63
5.6
5.2
432.0
370.4
umol/l
1.89
45
290
556
4907
1.16
2.63
5.2
4.7
2.8
2.5
ug/l
0.19
500
4379
67
449
1.50
2.60
1.6
1.4
3.7
5.0
ug/l
0.91
61
418
81
566
1.44
2.56
1.5
1.7
—
—
—
0
0
47
292
1.62
2.54
1.6
1.8
—
—
—
0
0
15
62
2.43
2.53
2.7
2.1
—
—
—
0
0
293
2454
1.22
2.52
7.5
7.3
105.4
104.5
mmol/l
2.35
287
2405
17
75
2.27
2.50
3.1
5.1
—
—
—
0
0
0
63
0.00
2.42
0.0
1.4
—
—
—
0
0
92
666
1.39
2.41
1.8
1.9
—
—
—
0
0
81
576
1.42
2.35
2.1
1.9
4.6
4.4
iu/l
0.09
31
205
43
267
1.62
2.35
1.5
1.5
—
—
—
0
0
261
2179
1.22
2.33
2.1
1.9
—
—
—
0
0
6
13
4.62
2.27
1.0
1.1
—
—
—
0
0
115
875
1.33
2.22
3.2
5.3
94.7
91.9
%
0.66
109
830
104
780
1.35
2.21
3.2
4.1
162.2
175.1
%
0.96
98
746
171
2110
0.80
2.18
1.6
1.6
—
—
—
0
0
23
122
1.89
2.15
1.6
1.6
—
—
—
0
0
114
871
1.32
2.15
2.1
1.7
—
—
—
0
0
91
672
1.37
2.15
1.8
2.6
354.1
398.8
ug/l
0.14
82
634
76
545
1.40
2.14
1.3
1.2
4.1
3.5
u/ml
—
6
52
665
6032
1.13
2.11
1.7
1.7
—
—
—
0
0
11
43
2.56
2.09
1.1
1.2
—
—
—
0
0
59
406
1.46
2.07
1.7
1.8
—
—
—
0
0
5
10
5.00
2.07
2.2
2.0
—
—
—
0
0
306
2625
1.19
2.07
2.4
2.1
—
—
—
0
0
28
161
1.75
2.05
1.6
1.6
32.1
33.3
%
0.05
15
105
19
96
1.98
2.05
1.1
1.1
145.2
278.5
ng/l
—
5
21
36
223
1.62
2.02
2.0
1.4
—
—
—
0
0
76
553
1.38
1.98
1.3
1.2
2.5
9.8
u/ml
—
7
87
81
596
1.37
1.98
3.3
2.7
—
—
—
0
0
81
596
1.37
1.98
1.3
1.2
11.3
43.7
u/ml
—
5
33
26
148
1.76
1.98
3.7
4.3
1.5
1.6
ug/l
0.10
26
140
104
797
1.32
1.95
1.2
1.1
—
—
—
0
0
39
249
1.57
1.95
1.3
1.5
372.2
387.0
pmol/l
0.07
31
196
5
11
4.55
1.94
3.2
5.7
—
—
—
0
0
16
78
2.06
1.90
1.1
1.1
—
—
—
0
0
21
114
1.85
1.87
1.0
1.1
1701.7
1558.3
miu/ml
0.20
21
114
8
28
2.86
1.86
1.4
2.2
1.5
1.8
mg/l
—
8
22
333
2906
1.16
1.84
1.8
1.7
1.4
1.4
%
0.06
297
2583
2087
20240
1.12
1.84
14.0
11.3
86.3
86.4
ml/min/173m2
0.07
1663
16181
69
502
1.38
1.83
1.2
1.3
—
—
—
0
0
69
502
1.38
1.83
1.2
1.3
—
—
—
0
0
30
183
1.65
1.81
1.2
1.1
—
—
—
0
0
30
183
1.65
1.81
1.2
1.1
—
—
—
0
0
21
116
1.82
1.78
3.7
3.0
320.3
187.9
umol/l
0.37
12
67
20
109
1.84
1.77
1.3
1.3
—
—
—
0
0
77
574
1.35
1.76
2.5
1.6
100.3
107.7
u/ml
0.23
18
89
30
185
1.63
1.75
1.2
1.1
—
—
—
0
0
30
185
1.63
1.75
1.2
1.1
—
—
—
0
0
279
2415
1.17
1.73
6.0
6.2
—
—
—
0
0
7
24
2.92
1.72
1.0
1.2
1.4
1.6
umol/24h
—
7
24
30
186
1.62
1.72
1.2
1.1
—
—
—
0
0
5
13
3.85
1.71
1.0
3.7
—
—
—
0
0
16
82
1.96
1.69
1.1
1.1
—
—
—
0
0
20
111
1.81
1.68
1.3
1.3
—
—
—
0
0
67
493
1.37
1.68
3.1
3.0
9.6
7.6
umol/l
0.29
55
383
27
164
1.65
1.67
1.8
1.7
—
—
—
0
0
10
43
2.33
1.60
1.6
2.0
—
—
—
0
0
37
246
1.51
1.60
4.3
4.3
6.4
7.1
mmol/l
1.05
29
209
78
594
1.32
1.58
2.3
1.6
—
—
—
0
0
7
26
2.70
1.58
1.3
1.2
—
—
—
0
0
186
1572
1.20
1.54
2.4
2.3
7.0
7.4
ug/l
0.07
166
1385
19
107
1.78
1.54
1.6
1.7
—
—
—
0
0
19
108
1.76
1.50
1.6
1.6
—
—
—
0
0
15
79
1.90
1.49
1.1
1.1
—
—
—
0
0
192
1635
1.19
1.47
1.1
1.1
—
—
—
0
0
9
38
2.37
1.45
1.1
1.1
—
—
—
0
0
15
80
1.88
1.44
1.1
1.1
—
—
—
0
0
106
855
1.25
1.41
1.3
1.8
1.5
1.5
g/l
0.04
88
744
15
81
1.86
1.40
1.1
1.1
—
—
—
0
0
75
580
1.30
1.40
1.5
1.3
—
—
—
0
0
58
432
1.35
1.39
1.3
1.2
3.3
4.7
u/ml
—
5
31
6
23
2.61
1.36
1.0
1.1
—
—
—
0
0
6
23
2.61
1.36
3.5
2.6
22.2
30.5
umol/l
—
6
23
59
443
1.34
1.35
1.0
1.1
—
—
—
0
0
397
3591
1.12
1.34
3.8
2.9
4.4
2.8
e6/l
0.97
215
1944
104
846
1.24
1.30
1.7
1.6
—
—
—
0
0
6
24
2.50
1.30
1.3
1.3
—
—
—
0
0
5
18
2.78
1.28
1.0
1.2
—
—
—
0
0
79
624
1.27
1.27
2.4
2.3
9.6
10.1
g/l
0.63
59
537
27
179
1.51
1.23
1.2
1.2
—
—
—
0
0
9
45
2.00
1.23
1.7
1.4
—
—
—
0
0
231
2031
1.15
1.22
2.6
2.3
35.5
61.4
u/l
0.56
193
1729
37
262
1.42
1.22
1.1
1.4
—
—
—
0
0
37
262
1.42
1.22
1.1
1.4
—
—
—
0
0
137
1155
1.20
1.22
1.5
1.4
—
—
—
0
0
8
37
2.16
1.21
2.0
2.7
—
—
—
0
0
53
400
1.33
1.20
1.1
1.0
1.3
3.8
u/ml
1.77
17
165
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
21
132
1.59
1.20
2.2
1.9
130.2
126.4
%
0.10
21
127
48
357
1.35
1.20
1.5
1.7
—
—
—
0
0
24
156
1.54
1.20
1.5
1.7
—
—
—
0
0
37
264
1.41
1.18
1.1
1.4
—
—
—
0
0
48
358
1.35
1.18
1.4
1.2
2.2
4.7
u/ml
1.70
24
159
17
102
1.67
1.16
1.1
1.1
—
—
—
0
0
212
1863
1.15
1.14
8.3
8.2
1.3
1.4
mmol/l
0.03
205
1766
43
317
1.36
1.14
1.6
1.4
6.6
6.9
mmol/l
0.39
30
224
63
493
1.28
1.12
3.5
3.0
35.4
36.4
umol/l
0.11
56
427
7
30
2.34
1.12
1.3
1.8
—
—
—
0
0
37
267
1.39
1.12
1.1
1.4
—
—
—
0
0
48
362
1.33
1.11
1.3
1.2
3.7
3.8
u/ml
0.01
23
119
57
443
1.29
1.08
1.8
1.5
—
—
—
0
0
34
244
1.40
1.07
2.8
2.2
26.2
29.8
mg/l
—
10
61
37
270
1.37
1.06
1.1
1.4
—
—
—
0
0
19
121
1.57
1.05
1.6
1.5
—
—
—
0
0
66
525
1.26
1.05
4.8
3.4
49.4
69.4
mg/l
0.63
43
427
66
526
1.26
1.03
4.8
3.4
26.6
47.6
mg/l
1.18
42
429
9
46
1.96
1.03
2.2
2.8
—
—
—
0
0
23
154
1.50
1.03
1.4
1.4
84.6
70.0
pmol/l
—
7
46
10
53
1.89
1.01
1.0
1.1
—
—
—
0
0
7
35
2.00
1.00
1.0
1.2
—
—
—
0
0
16
99
1.62
0.99
1.1
1.1
106.5
92.3
%
1.16
11
84
115
977
1.18
0.98
1.3
1.3
247.6
233.7
miu/ml
0.15
50
479
36
266
1.36
0.97
1.1
1.4
—
—
—
0
0
17
108
1.58
0.96
1.5
3.0
2040.3
1217.1
u/ml
0.27
17
108
85
704
1.21
0.96
2.1
1.4
—
—
—
0
0
176
1550
1.14
0.96
3.0
2.7
66.6
69.1
ml/min/173m2
0.32
86
588
14
85
1.65
0.94
1.2
1.2
—
—
—
0
0
86
716
1.21
0.93
2.3
2.0
6.1
1.9
ug/l
0.72
71
634
9
52
1.73
0.92
1.0
1.1
—
—
—
0
0
9
52
1.73
0.92
1.0
1.1
—
—
—
0
0
20
134
1.50
0.91
2.9
2.6
43.1
41.0
%
—
10
42
100
847
1.19
0.90
1.4
1.4
—
—
—
0
0
81
673
1.21
0.90
2.5
2.2
3.7
3.8
g/l
0.24
52
493
27
193
1.40
0.90
1.5
1.9
—
—
—
0
0
81
674
1.21
0.89
2.5
2.2
7.9
7.4
g/l
1.36
53
518
81
674
1.21
0.89
2.5
2.2
—
—
—
0
0
20
135
1.48
0.89
1.1
1.0
—
—
—
0
0
92
776
1.19
0.88
1.3
1.3
—
—
—
0
0
10
56
1.79
0.87
1.2
1.4
—
—
—
0
0
6
31
1.94
0.84
3.7
6.6
37.3
28.9
ug/min
—
6
26
6
32
1.88
0.81
1.0
1.0
—
—
—
0
0
137
1203
1.15
0.81
1.6
1.5
—
—
—
0
0
41
320
1.28
0.80
1.2
1.2
—
—
—
0
0
29
216
1.35
0.78
2.3
2.4
1744.2
764.5
e6/l
—
6
59
34
439
0.77
0.77
1.2
1.1
22.0
1202.8
iu/ml
—
6
121
0
28
0.00
0.76
0.0
2.8
—
0.7
—
0
28
11
67
1.64
0.75
1.2
1.5
—
—
—
0
0
31
236
1.32
0.74
1.2
1.3
—
32.4
—
0
5
221
2415
0.91
0.71
4.2
4.1
33.5
32.7
%
0.41
154
1656
16
109
1.47
0.70
1.2
1.1
—
—
—
0
0
88
758
1.17
0.70
1.7
1.7
—
—
—
0
0
35
275
1.28
0.68
1.2
1.3
—
0.4
nmol/l
—
0
17
49
401
1.23
0.68
1.6
1.4
—
—
—
0
0
42
338
1.25
0.67
1.2
1.1
109.9
115.3
%
0.46
35
310
11
168
0.65
0.67
1.1
1.4
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
15
102
1.47
0.67
1.5
1.2
92.6
100.8
%
0.36
15
95
7
43
1.63
0.66
1.1
1.2
—
—
—
0
0
14
94
1.49
0.66
1.1
1.0
—
—
—
0
0
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
25
188
1.33
0.66
4.0
4.0
—
—
—
0
0
13
86
1.51
0.66
1.2
1.2
0.3
0.3
g/l
—
8
74
27
206
1.31
0.65
1.1
1.2
48.5
74.2
u/l
1.88
18
152
45
367
1.23
0.65
1.1
1.1
—
—
—
0
0
10
62
1.61
0.65
1.4
1.1
94.6
81.1
%
—
5
14
80
690
1.16
0.64
2.2
1.5
256.5
232.7
u/ml
0.30
47
383
5
29
1.72
0.64
1.0
1.1
—
—
—
0
0
50
414
1.21
0.63
1.4
1.6
—
—
—
0
0
13
87
1.50
0.63
1.2
1.2
—
—
—
0
0
74
637
1.17
0.61
2.6
2.3
3.2
3.1
g/l
0.10
53
505
5
30
1.67
0.61
1.6
1.4
—
—
—
0
0
19
139
1.37
0.60
1.8
2.2
—
—
—
0
0
19
139
1.37
0.60
1.8
2.2
—
—
—
0
0
422
3992
1.07
0.59
2.5
2.2
—
—
—
0
0
8
53
1.51
0.58
1.3
1.1
—
—
—
0
0
85
744
1.15
0.58
1.4
1.5
—
—
—
0
0
116
1037
1.12
0.57
9.0
10.3
24.1
24.2
mmol/l
0.17
108
984
20
150
1.34
0.55
1.7
2.4
628.8
607.8
ml
—
10
102
13
183
0.71
0.55
1.8
2.5
—
—
—
0
0
6
38
1.58
0.54
1.3
1.0
—
—
—
0
0
6
40
1.50
0.51
1.0
1.1
—
—
—
0
0
6
41
1.46
0.50
1.0
1.1
—
—
—
0
0
21
162
1.30
0.50
1.5
1.4
—
—
—
0
0
7
46
1.52
0.48
1.9
1.2
—
—
—
0
0
75
662
1.14
0.48
3.3
3.5
556.7
2198.8
u/ml
0.54
63
570
456
4358
1.05
0.48
2.7
2.4
—
—
—
0
0
88
983
0.89
0.47
1.5
1.5
—
—
—
0
0
58
504
1.15
0.46
1.4
1.3
—
—
—
0
0
10
142
0.70
0.46
1.4
1.3
200.9
15.2
u/ml
—
5
111
29
237
1.23
0.45
1.1
1.1
—
—
—
0
0
57
499
1.14
0.42
1.4
1.4
—
—
—
0
0
15
113
1.33
0.42
1.0
1.5
5.2
7.9
u/l
—
10
97
17
131
1.30
0.42
1.4
1.5
2.0
6.5
u/l
—
7
67
20
158
1.27
0.41
1.5
1.5
0.9
1.0
g/l
0.31
20
158
5
34
1.47
0.40
2.2
1.2
—
—
—
0
0
27
223
1.21
0.39
1.1
1.1
—
—
—
0
0
18
142
1.27
0.38
1.4
1.3
181.9
361.1
u/l
3.82
18
136
13
98
1.33
0.37
1.2
1.6
—
—
—
0
0
13
98
1.33
0.37
1.2
1.6
—
—
—
0
0
13
98
1.33
0.37
1.2
1.6
—
—
—
0
0
13
98
1.33
0.37
4.2
4.1
—
—
—
0
0
13
98
1.33
0.37
1.2
1.6
—
—
—
0
0
5
37
1.35
0.37
1.4
1.3
9.8
24.0
%
—
5
29
27
320
0.84
0.35
1.3
1.2
—
—
—
0
0
63
700
0.90
0.34
1.1
1.1
3.7
3.6
u/ml
0.02
22
207
78
710
1.10
0.33
1.2
1.1
—
—
—
0
0
27
228
1.19
0.33
2.3
4.2
111.3
102.1
u/ml
0.05
12
70
83
759
1.10
0.33
1.6
1.5
—
—
—
0
0
49
435
1.13
0.32
1.1
1.1
—
—
—
0
0
28
238
1.18
0.32
1.4
1.7
—
—
—
0
0
77
704
1.10
0.31
1.2
1.1
—
—
—
0
0
7
52
1.35
0.31
3.4
2.7
—
—
—
0
0
7
52
1.35
0.31
3.4
2.7
—
—
—
0
0
7
53
1.32
0.30
1.0
1.1
—
—
—
0
0
82
890
0.92
0.30
1.5
1.4
—
—
—
0
0
28
240
1.17
0.30
1.6
1.5
—
—
—
0
0
82
889
0.92
0.29
1.5
1.4
—
—
—
0
0
298
2863
1.05
0.29
3.1
2.9
0.7
0.7
ug/l
0.38
196
1833
128
1201
1.07
0.29
1.6
1.6
—
—
—
0
0
119
1114
1.07
0.28
3.3
3.2
67.3
57.8
u/ml
0.11
114
1074
20
167
1.20
0.28
1.0
1.2
—
—
—
0
0
9
117
0.77
0.27
1.4
1.1
133.4
215.4
iu/ml
—
9
117
559
5446
1.03
0.27
2.3
2.3
—
—
—
0
0
32
280
1.14
0.27
1.5
1.3
—
—
—
0
0
21
177
1.19
0.27
1.5
1.4
49908.2
134888.5
e6/l
0.95
11
104
82
885
0.92
0.27
1.5
1.4
—
—
—
0
0
41
458
0.89
0.27
4.0
3.4
22.5
25.3
mg/l
0.25
29
288
10
77
1.30
0.26
1.2
1.7
—
—
—
0
0
10
77
1.30
0.26
1.2
1.7
—
—
—
0
0
51
463
1.10
0.25
1.2
1.2
—
—
—
0
0
31
273
1.14
0.25
1.4
1.6
—
—
—
0
0
20
233
0.86
0.24
1.6
1.4
10.8
11.5
mmol/l
—
5
48
113
1067
1.06
0.23
2.1
1.8
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
66
611
1.08
0.23
4.0
6.5
0.3
0.3
u/ml
1.84
40
342
5
39
1.28
0.23
1.4
2.4
7.0
7.9
mmol/l
—
5
20
14
116
1.21
0.22
1.2
1.3
197.6
337.0
u/l
0.64
14
106
30
336
0.89
0.21
3.7
3.9
23.8
31.9
u/ml
0.45
30
327
40
440
0.91
0.21
2.5
2.5
126.7
114.1
ug/min
0.04
17
270
25
220
1.14
0.21
1.7
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
5.8
—
—
—
0
0
10
80
1.25
0.20
1.2
1.7
—
—
—
0
0
9
111
0.81
0.20
1.1
2.5
37.2
307.3
ug/l
—
9
97
63
587
1.07
0.19
2.6
2.4
0.6
0.9
g/l
0.62
50
519
88
931
0.94
0.19
1.4
1.7
3.7
4.1
mg/l
0.14
61
633
79
838
0.94
0.19
1.7
1.7
—
—
—
0
0
25
222
1.13
0.19
1.8
1.7
—
—
—
0
0
84
887
0.95
0.18
1.5
1.4
—
—
—
0
0
30
330
0.91
0.17
2.7
3.0
1.0
0.8
nmol/l
0.77
23
262
23
205
1.12
0.17
1.6
1.4
9450.2
1800.7
e6/l
0.47
13
142
17
192
0.88
0.15
1.1
1.1
—
—
—
0
0
21
188
1.12
0.14
3.0
3.0
62.3
54.6
%
—
10
126
48
511
0.94
0.14
1.3
1.5
89.5
196.7
pmol/l
1.77
43
499
14
159
0.88
0.13
2.4
1.4
—
—
—
0
0
88
844
1.04
0.12
1.8
1.8
—
—
—
0
0
16
142
1.13
0.12
1.8
1.9
—
—
—
0
0
175
1797
0.97
0.12
3.9
4.1
2.8
18.8
ug/l
2.63
134
1440
187
1822
1.03
0.12
1.5
1.5
—
—
—
0
0
17
154
1.10
0.10
4.2
2.3
1.2
2.0
u/field
0.86
11
77
5
45
1.11
0.09
1.6
1.5
—
—
—
0
0
226
2302
0.98
0.09
26.0
22.7
1.4
1.3
inr
0.50
50
331
78
807
0.97
0.09
1.3
1.2
0.8
2.6
u/ml
2.45
37
433
54
518
1.04
0.08
1.1
1.1
11.6
6.8
u/ml
0.32
27
244
12
107
1.12
0.08
1.0
1.2
—
—
—
0
0
51
489
1.04
0.08
2.8
2.3
0.0
0.0
g/l
0.00
44
453
29
273
1.06
0.08
1.7
1.7
7.6
7.2
mmol/l
0.57
19
168
7
64
1.09
0.08
1.1
1.4
9.9
9.0
ug/l
—
7
64
49
470
1.04
0.08
1.1
1.1
14.7
8.4
u/ml
0.28
25
236
12
133
0.90
0.07
1.1
1.1
—
—
—
0
0
6
73
0.82
0.07
1.8
1.3
—
—
—
0
0
19
176
1.08
0.07
1.2
1.5
—
—
—
0
0
19
176
1.08
0.07
1.2
1.5
—
—
—
0
0
19
176
1.08
0.07
1.2
1.5
—
—
—
0
0
9
85
1.06
0.07
1.1
1.3
—
—
—
0
0
9
85
1.06
0.07
1.1
1.3
—
—
—
0
0
17
157
1.08
0.07
1.4
1.4
—
—
—
0
0
46
478
0.96
0.07
1.6
1.7
11602.9
13326.8
e6/l
0.13
33
351
21
223
0.94
0.06
1.1
1.1
—
—
—
0
0
10
90
1.11
0.05
1.1
1.0
—
—
—
0
0
22
208
1.06
0.05
1.1
1.2
98.0
209.0
titre
—
5
40
50
486
1.03
0.04
2.9
2.3
0.0
0.0
g/l
0.00
44
452
159
1571
1.01
0.04
1.3
1.3
—
—
—
0
0
59
603
0.98
0.03
1.2
1.3
—
—
—
0
0
35
340
1.03
0.03
1.1
1.1
—
—
—
0
0
51
501
1.02
0.02
1.6
1.8
—
—
—
0
0
11
117
0.94
0.02
1.1
1.0
19.6
19.5
mmol/l
0.04
11
108
42
428
0.98
0.01
1.1
1.1
0.0
0.4
u/ml
3.63
16
136
24
247
0.97
0.01
1.3
1.3
1.9
11.1
u/ml
0.92
11
115
53
524
1.01
0.00
2.8
2.2
0.0
0.0
g/l
0.51
46
486
54
534
1.01
0.00
2.7
2.2
37.9
37.8
g/l
0.05
45
469
16
164
0.98
0.00
2.9
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
2.8
—
0
9
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
1.0
1.2
—
—
—
0
0
6
67
0.89
0.00
1.5
1.5
—
—
—
0
0
6
60
1.00
0.00
1.3
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
0.00
1.7
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
0.00
1.7
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
15.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_HYPERMETRO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_HYPERMETRO | 1.047 [0.92, 1.2] | 0.5 |
| Birth year | 0.994 [0.99, 1.0] | 0.16 |
During the follow-up period (1.1.1998 — 31.12.2019), 1035 out of 19706 females with H7_HYPERMETRO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_HYPERMETRO | 1.28 [1.1, 1.49] | 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 874 out of 16671 males with H7_HYPERMETRO died.
Mortality risk
Mortality risk for people of age
years, who have H7_HYPERMETRO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.108% | 0.214% |
| 5 | 0.595% | 1.629% |
| 10 | 1.473% | 3.821% |
| 15 | 2.768% | 7.326% |
| 20 | 4.922% | 12.191% |
Relationships between endpoints
↥Index endpoint: H7_HYPERMETRO – Hypermetropia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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