sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3991 |
4. Check minimum number of eventsNone |
3991 |
5. Include endpointsNone |
3991 |
6. Filter based on genotype QC (FinnGen only) |
3991 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H91
- Name in latin
- Hypacusis acuta idiopathica
Similar endpoints
↥List of similar endpoints to
Sudden idiopathic hearing loss
based on the number of shared cases.
Similar with more cases:
- Other hearing loss
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 24447 | 12128 | 12214 |
| Only index persons | 23111 | 11603 | 11508 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.34 | 0.35 | 0.34 |
| Only index persons | 0.43 | 0.43 | 0.44 |
| Median age at first event (years) | |||
| Whole population | 58.15 | 58.52 | 57.78 |
| Only index persons | 57.56 | 57.96 | 57.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3991 | 2079 | 1912 |
| Unadjusted period prevalence (%) | 0.77 | 0.71 | 0.84 |
| Median age at first event (years) | 58.18 | 56.08 | 60.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3620
- Matched controls
- 36198
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
113.3
323.0
1128
144
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
343.1
323.0
648
23
Z01.1
ICD-10 Finland
Examination of ears and hearing
12.7
323.0
1172
1317
N07CA01
ATC
betahistine; oral
18.8
323.0
1215
948
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
16384.0
323.0
3418
22
DFF00
NOMESCO Finland
Pure tone audiometry
28.6
323.0
1028
494
UDC00
NOMESCO Finland
Ear microscopy
10.9
300.4
612
663
3882A
ICD-9 Finland
Other disorders of ear, Sudden hearing loss, unspecified
+∞
252.0
239
*
H02AB06
ATC
prednisolone; systemic
3.3
250.2
2262
12110
H81.0
ICD-10 Finland
Ménière disease
24.3
237.3
344
156
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
91.5
237.0
263
31
H93.1
ICD-10 Finland
Tinnitus
14.4
234.7
413
321
H91.9
ICD-10 Finland
Hearing loss, unspecified
17.6
234.5
380
240
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
17.6
229.8
372
234
DFF15
NOMESCO Finland
Speech audiometry
20.5
223.6
342
183
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
58.7
221.7
262
48
H02
ICPC
Hearing complaint
5.5
210.9
696
1499
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
104.1
180.1
197
20
DAX08
NOMESCO Finland
Fitting of hearing aid
27.3
160.6
224
87
Z97.4
ICD-10 Finland
Presence of external hearing-aid
19.0
144.7
226
126
SPAT1043
SPAT
Audiometry
4.7
134.5
505
1212
R42
ICD-10 Finland
Dizziness and giddiness
2.8
128.1
1021
4437
H02AB04
ATC
methylprednisolone; systemic
2.8
96.3
708
2858
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
86.6
90.5
101
12
DFF59
NOMESCO Finland
Other assessment of balance
21.2
90.1
135
66
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
217.4
82.7
85
*
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
13.3
81.6
146
114
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
255.2
73.6
75
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
13.5
66.7
118
90
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
12.6
63.0
115
94
H81.3
ICD-10 Finland
Other peripheral vertigo
5.6
60.1
182
336
DC1AD
NOMESCO Finland
Temporalbone CT
21.2
57.1
85
41
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
24.0
55.9
80
34
R5120
NOMESCO Finland
Preparation of an aid
8.1
51.6
119
151
H29
ICPC
Ear symptom/complaint other
2.6
50.9
410
1698
DFE00
NOMESCO Finland
Insertion of cochlear implant
+∞
49.1
47
*
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
57.8
48.5
57
10
D33.30
ICD-10 Finland
Acoustic neuroma
24.7
48.1
68
28
H91.8
ICD-10 Finland
Other specified hearing loss
15.3
46.8
78
52
H91.1
ICD-10 Finland
Presbycusis
5.0
46.6
157
328
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
44.1
1578
11524
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
43.1
314
1223
A02BC02
ATC
pantoprazole; systemic
1.6
42.7
2266
18317
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.5
41.8
155
358
AA1AD
NOMESCO Finland
CT of head and brain
1.8
40.6
870
5430
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.4
40.5
370
1630
R4135
NOMESCO Finland
Rehabilitation for hearing problems
26.6
39.8
55
21
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
36.0
407
1984
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
35.5
670
3987
H92.0
ICD-10 Finland
Otalgia
3.5
34.0
166
491
R01AD09
ATC
mometasone; nasal
1.6
33.6
1428
10654
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
32.6
313
1411
H13
ICPC
Plugged feeling ear
1.8
32.2
612
3636
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
53.3
31.3
37
7
N02BE01
ATC
paracetamol; systemic, rectal
1.7
31.3
2976
26611
H28
ICPC
Limited function/disability (H)
9.7
30.8
63
66
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
30.8
1628
12687
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
30.8
733
4667
A02BC03
ATC
lansoprazole; oral
1.6
28.8
997
7009
J01FA10
ATC
azithromycin; systemic
1.5
28.2
1805
14546
J01CA04
ATC
amoxicillin; systemic
1.5
28.1
2658
23286
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
100.8
27.7
30
*
SPAT1263
SPAT
Sampling
1.5
27.6
1388
10611
R01AD12
ATC
fluticasone furoate; nasal
1.6
26.7
849
5821
R51.80
ICD-10 Finland
Headache
1.9
26.5
447
2536
A02BC05
ATC
esomeprazole; systemic
1.5
26.4
1346
10293
SPAT1153
SPAT
Removal of sutures
1.5
26.4
1090
7957
DFF16
NOMESCO Finland
Speech-in-noise audiometry
+∞
26.1
25
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
25.9
1495
11719
R01AD08
ATC
fluticasone; nasal
1.6
25.6
885
6186
H81.2
ICD-10 Finland
Vestibular neuronitis
4.1
25.3
101
252
TDA90
NOMESCO Finland
Removal wax from ear
7.1
25.3
62
88
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
50.4
25.2
30
6
J01AA02
ATC
doxycycline; systemic
1.5
25.2
2639
23265
M03BX02
ATC
tizanidine; oral
1.4
25.0
1974
16426
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
24.9
955
6833
M01AH05
ATC
etoricoxib; oral
1.4
24.9
1903
15727
SPAT1312
SPAT
General health counselling
1.5
24.8
1002
7259
J01DB01
ATC
cefalexin; oral
1.5
24.5
2749
24497
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.5
24.1
115
335
DFX00
NOMESCO Finland
Connecting cochlear implant
+∞
24.0
23
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
23.7
1084
8050
C03EA02
ATC
trichlormethiazide and potassium-sparing agents; oral
3.9
23.7
99
258
SPAT1310
SPAT
Counselling related to known health issue
1.5
23.3
1029
7581
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.2
23.3
90
219
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
22.7
334
1801
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
22.0
721
4948
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
21.7
1360
10716
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
21.5
535
3412
G44.2
ICD-10 Finland
Tension-type headache
1.8
21.4
391
2274
A98
ICPC
Health maint/preventive medicine
1.8
21.1
3348
31590
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
20.2
740
5203
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
20.1
397
2363
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
9.8
20.0
40
41
M01AE02
ATC
naproxen; oral, rectal
1.4
19.9
1760
14681
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
19.8
555
3653
N17
ICPC
Vertigo/dizziness
1.8
19.7
349
2008
H61.2
ICD-10 Finland
Impacted cerumen
2.3
19.2
189
858
M25.5
ICD-10 Finland
Pain in joint
1.5
19.0
847
6201
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
18.9
863
6349
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
18.8
1146
8919
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
18.8
921
6875
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.4
18.3
161
693
N06AX11
ATC
mirtazapine; oral
1.4
18.2
968
7338
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
17.9
1148
8997
N02AX02
ATC
tramadol; systemic, rectal
1.4
17.5
1361
11021
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
17.5
299
1698
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
17.1
1246
9968
R03AC02
ATC
salbutamol; inhalant
1.4
17.1
1592
13266
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
16.9
921
6996
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
16.6
749
5476
S18
ICPC
Laceration/cut
1.4
16.6
1354
11023
N03AX12
ATC
gabapentin; oral
1.6
16.5
475
3137
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
16.4
2169
19041
SPAT1041
SPAT
Comprehensive hearing test
5.4
16.3
48
89
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
16.3
1268
10235
DFF50
NOMESCO Finland
Electronystagmography
21.0
16.0
23
11
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
15.8
153
691
SPAT1301
SPAT
No procedures
1.4
15.8
982
7621
H83.1
ICD-10 Finland
Labyrinthine fistula
60.2
15.8
18
*
Z45.3
ICD-10 Finland
Adjustment and management of implanted hearing device
+∞
15.6
15
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
15.5
585
4115
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
15.0
1671
14200
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
15.0
305
1827
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
14.8
569
4016
H25.8
ICD-10 Finland
Other senile cataract
1.7
14.6
338
2106
R06.0
ICD-10 Finland
Dyspnoea
1.4
14.6
761
5708
M54.5
ICD-10 Finland
Low back pain
1.4
14.5
956
7476
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.7
14.4
320
1969
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.8
14.4
237
1330
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
14.2
242
1370
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
14.1
505
3507
UKC02
NOMESCO Finland
Cystoscopy
1.5
14.1
516
3600
M79.1
ICD-10 Finland
Myalgia
1.6
14.0
362
2323
H80.9
ICD-10 Finland
Otosclerosis, unspecified
6.7
14.0
35
53
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
13.9
722
5404
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
13.8
337
2129
M79.6
ICD-10 Finland
Pain in limb
1.4
13.8
1060
8487
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.7
13.7
273
1625
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
75.4
13.6
15
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
3.8
13.5
56
148
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
13.5
538
3819
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
13.4
199
1076
R01AD01
ATC
beclometasone; nasal
1.5
13.2
439
2993
M02AA07
ATC
piroxicam; topical
1.3
13.2
1130
9183
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
13.2
290
1778
N03AX16
ATC
pregabalin; oral
1.4
13.2
710
5344
H01
ICPC
Ear pain/earache
1.7
13.1
276
1669
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
15.1
13.1
21
14
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
13.1
545
3904
N05CF01
ATC
zopiclone; oral
1.3
13.0
1001
7998
A02BC01
ATC
omeprazole; systemic
1.4
13.0
837
6498
H66.9
ICD-10 Finland
Otitis media, unspecified
2.2
13.0
132
615
A02BC04
ATC
rabeprazole; oral
1.8
12.9
238
1382
SPAT1260
SPAT
Consultation of another employee
1.5
12.9
532
3805
DE2CF
NOMESCO Finland
Acoustic channel extensive MRI examination with median intensity magnet
50.2
12.8
15
*
R74
ICPC
Upper respiratory infection acute
1.4
12.7
722
5484
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
5.4
12.7
37
69
H83.3
ICD-10 Finland
Noise effects on inner ear
5.8
12.7
35
61
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
6.4
12.6
32
50
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
+∞
12.5
12
*
UJF32
NOMESCO Finland
Coloscopy
1.4
12.5
792
6127
H03
ICPC
Tinnitus, ringing/buzzing ear
3.3
12.5
62
191
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
12.4
162
838
J01FF01
ATC
clindamycin; systemic
1.4
12.3
801
6222
SPAT1325
SPAT
Vaccination
1.3
12.3
1056
8571
SPAT1216
SPAT
Assessment of functional ability
1.5
12.1
467
3288
SPAT1097
SPAT
Recording of ECG
1.5
12.1
455
3188
XKD00
NOMESCO Finland
Uroflowmetry
1.5
12.1
504
3607
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
18.1
12.0
18
10
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
12.0
983
7915
H60.3
ICD-10 Finland
Other infective otitis externa
2.9
11.9
71
248
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
11.9
407
2791
J01FA09
ATC
clarithromycin; systemic
1.3
11.9
909
7238
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
11.9
658
4968
J05AB01
ATC
aciclovir; systemic
1.4
11.8
600
4458
D82
ICPC
Teeth/gum disease
1.3
11.8
942
7549
J01DA01
ATC
[U] cefalexin; systemic
1.3
11.8
1955
17311
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
11.7
1001
8105
R06AE07
ATC
cetirizine; oral
1.3
11.6
1246
10410
Z97.8
ICD-10 Finland
Presence of other specified devices
16.4
11.6
18
11
R05
ICPC
Cough
1.4
11.6
633
4761
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
11.6
906
7235
H84
ICPC
Presbyacusis
2.7
11.5
80
305
G47.3
ICD-10 Finland
Sleep apnoea
1.4
11.5
608
4552
H91.3
ICD-10 Finland
Deaf mutism, not elsewhere classified
+∞
11.5
11
*
DC1AI
NOMESCO Finland
Cone beam CT of ear
120.3
11.4
12
*
L01
ICPC
Neck symptom/complaint
1.5
11.4
363
2451
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.8
11.4
203
1171
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
11.3
2944
27625
K08.80
ICD-10 Finland
Toothache NOS
1.8
11.3
202
1166
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
11.2
407
2828
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
11.1
181
1014
L17
ICPC
Foot/toe symptom/complaint
1.4
11.1
751
5860
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
11.0
191
1090
M01AB05
ATC
diclofenac; systemic, rectal
1.3
11.0
2086
18706
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
11.0
390
2695
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
11.0
682
5245
J02AC01
ATC
fluconazole; systemic
1.3
10.8
1095
9059
R05
ICD-10 Finland
Cough
1.4
10.8
541
4009
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.9
10.8
168
926
DDA00
NOMESCO Finland
Stapedotomy
7.2
10.7
25
35
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
10.7
243
1505
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
10.7
244
1515
A06AC51
ATC
ispaghula, combinations; systemic
1.9
10.6
148
786
C10AA07
ATC
rosuvastatin; oral
1.3
10.5
751
5901
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
10.5
698
5423
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
10.5
175
987
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
10.5
381
2651
C07AB07
ATC
bisoprolol; oral
1.3
10.4
1515
13115
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.0
10.4
135
697
L08
ICPC
Shoulder symptom/complaint
1.4
10.3
552
4131
L03
ICPC
Low back symptom/complaint
1.4
10.3
685
5320
A02BA02
ATC
ranitidine; systemic
1.4
10.3
585
4423
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
10.3
253
1602
H71
ICD-10 Finland
Cholesteatoma of middle ear
5.1
10.3
31
61
N05BA04
ATC
oxazepam; oral
1.3
10.3
707
5520
R06AX27
ATC
desloratadine; oral
1.4
10.3
686
5332
K07.60
ICD-10 Finland
Snapping jaw
2.0
10.2
119
591
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
10.2
629
4829
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
10.1
437
3143
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
10.1
407
2889
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
10.1
209
1264
SPAT1211
SPAT
Application of soft bandage
1.6
10.1
262
1683
J05AB11
ATC
valaciclovir; oral
1.5
10.1
372
2592
SPAT1044
SPAT
Tympanometry
2.8
10.0
63
229
Z01.2
ICD-10 Finland
Dental examination
1.3
10.0
1136
9524
C01CA24
ATC
epinephrine; parenteral
1.9
10.0
152
833
N05AB04
ATC
prochlorperazine; systemic, rectal
2.5
10.0
75
303
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
10.0
282
1851
WX110
NOMESCO Finland
Local anesthesy
1.3
9.9
2118
19149
E0000UV
ATC
NA
1.3
9.9
1142
9586
H02AB07
ATC
prednisone; oral
1.4
9.9
419
3004
D07AC13
ATC
mometasone; topical
1.3
9.7
842
6802
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.0
9.7
121
615
XQ800
NOMESCO Finland
Prick test
1.7
9.6
184
1085
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.8
9.6
155
865
J37.0
ICD-10 Finland
Chronic laryngitis
2.2
9.6
95
437
X58
ICD-10 Finland
Exposure to other specified factors
1.5
9.6
369
2593
G04CA02
ATC
tamsulosin; oral
1.3
9.6
685
5375
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
9.6
2101
19016
H91
ICD-10 Finland
Other hearing loss
5.0
9.5
29
58
H53.1
ICD-10 Finland
Subjective visual disturbances
1.8
9.5
169
977
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
9.4
323
2216
R21
ICPC
Throat symptom/complaint
1.4
9.4
462
3404
DCA30
NOMESCO Finland
Exploration of middle ear
30.1
9.4
12
*
XA410
NOMESCO Finland
BAEP
+∞
9.4
9
*
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
9.4
1663
14678
J01MA02
ATC
ciprofloxacin; systemic
1.3
9.3
1182
10032
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
9.2
332
2299
XG410
NOMESCO Finland
Flow-volume spirometry
2.0
9.2
120
622
H26.4
ICD-10 Finland
After-cataract
1.6
9.2
251
1630
R13
ICD-10 Finland
Dysphagia
1.7
9.2
180
1071
N01
ICPC
Headache
1.6
9.2
226
1434
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.1
1375
11895
J01MA01
ATC
ofloxacin; systemic
1.6
9.1
255
1670
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
9.1
757
6069
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
9.1
432
3164
H65.0
ICD-10 Finland
Acute serous otitis media
3.5
9.1
40
114
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.6
9.1
220
1391
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
9.1
456
3374
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
9.0
232
1487
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
8.9
1015
8489
SPAT1053
SPAT
Memory test
1.4
8.9
431
3172
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.5
8.8
265
1763
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
2.9
8.8
52
183
R07.0
ICD-10 Finland
Pain in throat
1.8
8.7
149
850
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.6
8.7
205
1285
C05AA08
ATC
fluocortolone; rectal, topical
1.4
8.7
401
2922
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
8.7
139
777
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
8.6
1269
10933
F45.8
ICD-10 Finland
Other somatoform disorders
1.8
8.6
146
832
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.6
1254
10792
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.3
8.6
691
5514
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.5
1855
16673
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.5
1188
10172
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
8.4
508
3876
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.4
431
3202
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
3.4
8.4
39
117
B01AA03
ATC
warfarin; systemic
1.3
8.4
601
4713
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.5
8.4
242
1599
3897A
ICD-9 Finland
Deafness, Deaf mutism, not elsewhere classifiable[SURDITAS]
+∞
8.3
8
*
DFD20
NOMESCO Finland
Closure of rupture of round window
+∞
8.3
8
*
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
3.3
8.3
40
123
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
8.3
389
2841
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
8.3
728
5872
H01.0
ICD-10 Finland
Blepharitis
1.8
8.3
136
768
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.7
8.3
176
1072
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
8.2
1020
8599
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
8.2
322
2273
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
14.5
8.2
13
9
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
8.2
706
5682
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
8.1
363
2633
C08CA05
ATC
nifedipine; systemic
1.6
8.0
184
1147
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
8.0
1144
9798
B01AF01
ATC
rivaroxaban; oral
1.4
8.0
354
2554
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
2.6
8.0
56
219
L57.0
ICD-10 Finland
Actinic keratosis
1.5
8.0
287
1993
R04.0
ICD-10 Finland
Epistaxis
1.6
8.0
205
1315
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
7.9
161
969
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.0
7.9
99
505
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.6
7.9
186
1168
H81
ICPC
Excessive ear wax
1.4
7.9
437
3287
Z00.0
ICD-10 Finland
General medical examination
1.3
7.9
524
4060
ZXA10
NOMESCO Finland
Bilateral
1.3
7.9
526
4076
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
7.8
7.9
17
22
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.8
1143
9810
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.9
7.8
113
611
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.3
7.7
69
304
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
7.7
718
5833
C10AA05
ATC
atorvastatin; oral
1.2
7.7
1205
10414
R51
ICD-10 Finland
Headache
1.8
7.7
124
697
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.4
7.7
64
275
C09CA06
ATC
candesartan; oral
1.3
7.7
608
4830
WZA90
NOMESCO Finland
Other doctors statement
1.3
7.6
627
5008
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.6
764
6268
H60.8
ICD-10 Finland
Other otitis externa
2.2
7.6
69
311
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
7.5
149
892
M48.0
ICD-10 Finland
Spinal stenosis
1.4
7.5
353
2580
SPAT1058
SPAT
PEF monitoring instruction
1.5
7.5
228
1523
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.2
7.5
73
336
D06
ICPC
Abdominal pain localized other
1.6
7.5
202
1311
SPAT1104
SPAT
Monitoring of emergency patient
1.6
7.5
189
1207
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.4
757
6218
AAE32
NOMESCO Finland
Translabyrinthine excision acoustic neurinome
80.2
7.4
8
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
80.2
7.4
8
*
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.4
1609
14375
G50.0
ICD-10 Finland
Trigeminal neuralgia
2.6
7.4
49
187
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.4
7.4
303
2158
A03FA02
ATC
cisapride; oral, rectal
1.5
7.4
223
1489
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.4
7.4
61
261
A03
ICPC
Fever
1.4
7.3
372
2758
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.7
7.3
131
763
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
+∞
7.3
7
*
38920
ICD-8 Finland
Other deafness, Deafness, one ear
+∞
7.3
7
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
7.3
74
1335
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.8
7.3
43
153
C10AA01
ATC
simvastatin; oral
1.2
7.3
1391
12261
H04.10
ICD-10 Finland
Dry eye syndrome
1.5
7.3
247
1695
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
7.2
1515
13477
SPAT1254
SPAT
Administration of medicine
1.4
7.2
398
2994
K59.0
ICD-10 Finland
Constipation
1.7
7.2
147
890
M01AX05
ATC
glucosamine; oral
1.3
7.1
600
4808
J01MA12
ATC
levofloxacin; systemic
1.3
7.1
527
4147
TAB00
NOMESCO Finland
Lumbar puncture
1.8
7.1
109
605
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
7.1
640
5174
N03AX11
ATC
topiramate; oral
2.4
7.1
56
234
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.0
7.1
89
461
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.0
840
7028
L12
ICPC
Hand/finger symptom/complaint
1.4
7.0
365
2715
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
7.0
413
3140
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
7.0
447
3441
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.4
7.0
277
1962
G43.9
ICD-10 Finland
Migraine, unspecified
1.8
7.0
115
651
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.5
6.9
208
1389
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.5
6.9
206
1374
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.5
6.9
248
1723
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
13.8
6.9
11
8
G35
ICD-10 Finland
Multiple sclerosis
2.7
6.9
45
171
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.1
6.9
69
326
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
6.8
105
584
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.4
6.8
332
2441
Z04.3
ICD-10 Finland
Examination and observation following other accident
2.2
6.8
63
286
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
10.9
6.8
12
11
M01AX17
ATC
nimesulide; oral
1.3
6.8
717
5912
R03BA05
ATC
fluticasone; inhalant
1.3
6.7
463
3602
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.7
170
1089
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
6.7
647
5275
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
6.7
681
5589
J02AC02
ATC
itraconazole; systemic
1.3
6.7
483
3785
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.7
1193
10423
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.5
6.6
239
1659
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
2.4
6.6
51
213
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.7
6.6
135
819
R03DC03
ATC
montelukast; oral
1.3
6.6
404
3086
3870A
ICD-9 Finland
Otosclerosis involving oval window, nonobliterative
5.9
6.6
17
29
DHB50
NOMESCO Finland
Turbinoplasty
2.1
6.6
65
306
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
6.5
473
3706
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
6.5
1864
17017
N06AB10
ATC
escitalopram; oral
1.3
6.4
474
3723
H91.0
ICD-10 Finland
Ototoxic hearing loss
69.9
6.4
7
*
L15
ICPC
Knee symptom/complaint
1.3
6.4
567
4567
M54.2
ICD-10 Finland
Cervicalgia
1.6
6.4
173
1126
XF402
NOMESCO Finland
ECG with work load test
1.4
6.4
317
2340
I73.0
ICD-10 Finland
Raynaud syndrome
2.6
6.4
42
160
R5599
NOMESCO Finland
Other rehabilitation service
2.1
6.4
70
342
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.4
1028
8874
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.6
6.4
146
914
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
6.3
764
6390
A01
ICPC
Pain general/multiple sites
1.5
6.3
198
1337
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
6.3
425
3295
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
8.1
6.3
13
16
R00.2
ICD-10 Finland
Palpitations
1.6
6.3
172
1123
J01DC02
ATC
cefuroxime; systemic
1.6
6.3
139
862
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.3
6.3
645
5292
C01DA14
ATC
isosorbide mononitrate; oral
1.3
6.3
424
3290
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.6
6.3
170
1112
DE2DM
NOMESCO Finland
Very extensive 3 T MRI of internal auditory canal
+∞
6.2
6
*
3883A
ICD-9 Finland
Other disorders of ear, Tinnitus
+∞
6.2
6
*
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.8
6.2
105
600
UDM02
NOMESCO Finland
Sinoscopy
2.1
6.2
64
305
R02
ICPC
Shortness of breath/dyspnoea
1.4
6.2
313
2318
R53
ICD-10 Finland
Malaise and fatigue
1.3
6.2
537
4309
FN1AD
NOMESCO Finland
CT of coronary arteries
2.5
6.2
44
175
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.2
1105
9636
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
5.0
6.2
18
36
J01EA01
ATC
trimethoprim; systemic
1.3
6.2
675
5586
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
6.1
301
2216
H69.0
ICD-10 Finland
Patulous Eustachian tube
5.7
6.1
16
28
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.6
6.1
148
938
R15
ICD-10 Finland
Faecal incontinence
2.0
6.1
70
348
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.8
6.1
89
487
R05FB02
ATC
cough suppressants and expectorants
1.2
6.0
1106
9664
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.0
270
1959
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
1.5
6.0
213
1478
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
576
1895
3.38
140.21
1.3
1.3
24.9
51.2
au/ml
2.66
18
84
610
2097
3.25
138.11
2.5
2.4
31.0
21.9
au/ml
0.50
19
95
845
3997
2.41
101.13
4.8
4.6
33.1
32.5
%
0.75
585
2617
1770
12660
1.72
58.13
4.1
3.6
51.0
84.8
ng/l
0.43
1263
8975
2868
24141
1.67
44.19
4.9
4.1
12.1
13.0
mm/h
2.36
2605
22239
3346
29592
1.81
40.62
5.3
4.7
1.9
2.1
mu/l
1.43
2998
26932
3585
32513
2.01
38.78
17.2
15.0
21.5
25.0
mg/l
7.93
2886
25999
3696
33986
2.18
37.06
20.0
17.5
4.0
4.0
mmol/l
0.19
3588
33102
3684
33886
2.13
36.05
19.8
17.4
139.7
139.6
mmol/l
1.02
3586
33058
1788
13967
1.51
34.01
11.5
9.5
1.3
1.3
inr
0.66
501
3950
2936
25661
1.55
30.88
8.6
7.8
77.3
79.1
u/l
1.19
2717
24193
1327
9956
1.50
29.51
3.3
3.0
1754.0
1512.1
ng/l
0.55
1101
8607
3817
36011
2.38
28.40
25.8
22.0
6.8
6.8
e9/l
0.01
3716
34915
1350
10224
1.48
28.40
2.4
2.2
211.9
214.7
u/l
0.03
1238
9574
3815
35987
2.36
28.35
25.8
22.0
245.5
248.4
e9/l
2.04
3725
35030
3816
36004
2.37
28.28
25.8
22.0
4.5
4.5
e12/l
0.06
3719
34903
3474
31796
1.71
28.19
5.1
4.7
6.0
6.0
mmol/l
0.17
3075
28864
2808
24489
1.49
28.19
4.4
3.9
15.0
14.9
pmol/l
3.17
2508
22178
3715
34706
2.02
28.07
12.4
10.7
26.0
26.4
u/l
0.53
3524
33445
1891
15304
1.45
28.06
6.6
6.1
1.2
1.2
mmol/l
2.68
1658
13871
3816
36016
2.36
28.05
25.9
22.1
135.1
135.0
g/l
0.16
3756
35483
1356
10345
1.47
27.20
2.8
2.6
55.8
57.9
u/l
1.29
1227
9543
3472
31905
1.68
26.08
5.1
4.5
1.5
1.5
mmol/l
0.02
3108
29242
631
4116
1.63
25.69
7.3
6.9
—
—
—
0
0
2323
19719
1.43
25.44
5.3
4.8
6.8
6.8
mmol/l
0.30
2177
18497
3324
30286
1.58
25.08
6.5
5.9
40.1
40.1
mmol/mol
0.14
2988
27939
3488
32157
1.67
25.05
5.1
4.5
4.6
4.6
mmol/l
3.19
3141
29647
3370
30836
1.60
24.61
4.5
4.0
1.3
1.3
mmol/l
0.47
3003
28042
253
1269
2.06
24.41
3.9
4.0
25.2
24.9
mmol/l
0.76
237
1164
1644
13320
1.40
22.45
2.4
2.2
79.6
78.0
nmol/l
1.53
1437
11897
3533
32851
1.66
22.42
5.5
5.0
2.7
2.7
mmol/l
3.16
3152
30125
872
6297
1.49
22.25
1.8
1.8
1157.3
1163.0
nmol/l
0.06
624
4736
2414
20888
1.39
22.03
3.4
3.1
47.7
52.0
u/l
1.65
2185
19306
2077
17536
1.38
21.95
6.4
6.4
11.3
11.6
umol/l
0.43
1940
16664
3360
30919
1.55
21.78
15.4
14.2
77.3
78.9
ml/min/173m2
4.38
2837
25563
359
2101
1.78
21.67
3.8
3.7
5.1
5.2
kpa
0.21
329
1941
2005
16875
1.38
21.36
7.6
6.9
1.2
1.2
mmol/l
1.14
1627
14231
2483
21652
1.39
21.20
5.2
4.5
592.2
1181.0
e6/l
0.58
24
315
2006
16910
1.37
21.03
6.6
6.0
0.2
0.2
e9/l
0.14
1774
14684
1842
15355
1.37
20.51
6.9
6.0
2.9
2.8
%
0.18
1698
14277
340
1997
1.77
20.24
3.7
3.6
2.0
1.9
mmol/l
0.25
262
1496
1879
15798
1.36
19.41
7.0
6.1
27.1
27.2
%
0.23
1717
14663
104
395
2.68
19.06
2.1
2.1
25.5
24.6
mg/l
0.05
33
98
1663
13793
1.35
18.44
2.1
2.0
96.8
94.3
pmol/l
1.20
862
7116
1848
15575
1.35
18.43
6.6
5.9
58.1
57.7
%
0.65
1699
14526
727
5263
1.47
17.86
1.3
1.3
36.0
34.6
iu/ml
0.08
215
1657
1960
16734
1.34
17.60
6.6
5.9
1.9
1.9
e9/l
0.09
1756
14562
1614
13399
1.34
17.49
3.3
2.8
141.4
138.9
ug/l
0.10
1456
12352
1746
14671
1.34
17.41
5.2
5.0
35.6
35.1
g/l
3.21
1589
13617
677
4954
1.44
15.52
1.3
1.2
12.6
12.9
u/ml
0.03
213
1880
229
1296
1.81
15.43
1.8
1.8
—
—
—
0
0
242
1401
1.77
15.11
1.9
1.9
—
—
—
0
0
1063
8437
1.35
14.97
2.5
2.2
3.1
3.0
mg/l
1.34
899
7198
1380
11408
1.32
14.65
3.1
3.5
2.3
2.4
mmol/l
1.07
1119
9935
839
6527
1.36
13.20
1.3
1.2
1.7
1.9
u/ml
0.18
205
1712
899
7070
1.35
13.18
1.7
1.7
16620156.0
28540217.2
pmol/l
0.42
710
5869
2150
19066
1.28
12.65
8.9
9.2
4.1
4.2
e9/l
0.37
1904
16525
127
641
2.01
12.15
1.4
1.2
—
252.3
—
0
13
1086
8874
1.31
12.02
2.8
2.8
1815.0
5441.8
umol/l
4.95
919
7652
977
7874
1.32
11.94
1.6
1.5
21.1
20.4
nmol/l
0.75
784
6716
714
5506
1.36
11.74
2.0
1.8
—
—
—
0
0
1009
8195
1.31
11.61
2.6
2.4
—
—
—
0
0
492
3571
1.43
11.58
2.4
2.2
119.5
149.9
ug/g
1.25
376
2813
2071
18514
1.25
10.46
2.8
2.7
—
—
—
0
0
1771
15664
1.23
9.51
4.2
4.1
—
—
—
0
0
86
419
2.08
9.15
1.3
1.5
—
—
—
0
0
84
407
2.09
9.07
1.3
1.5
—
—
—
0
0
84
408
2.08
9.01
1.3
1.5
—
—
—
0
0
84
409
2.08
8.96
1.3
1.5
—
—
—
0
0
3105
29275
1.27
8.89
17.0
16.2
39.5
39.6
%
0.06
1962
20499
181
1124
1.64
8.83
1.9
1.6
231.4
289.0
titre
0.23
14
51
133
760
1.78
8.80
1.1
1.1
3.1
6.1
u/ml
—
9
79
394
2891
1.40
8.67
2.2
2.2
371.5
374.2
nmol/l
0.09
359
2649
1248
10735
1.24
8.42
3.4
3.2
7.7
7.5
mmol/l
0.86
989
8972
1368
11887
1.23
8.38
5.7
5.0
2.9
3.3
ug/l
0.38
1218
10647
83
413
2.03
8.38
1.4
1.5
—
—
—
0
0
83
415
2.02
8.27
1.3
1.5
—
—
—
0
0
118
667
1.79
8.13
4.5
3.8
58.4
57.7
%
0.25
118
667
590
4663
1.31
7.99
32.8
25.3
1.3
1.4
inr
0.31
79
679
1198
10306
1.23
7.99
3.4
3.3
550.2
324.1
mg/l
0.70
702
6568
661
5316
1.29
7.85
3.2
2.6
13.2
12.8
umol/l
0.80
597
4933
612
4920
1.29
7.25
3.3
2.6
2.3
2.3
g/l
0.29
553
4564
578
4619
1.29
7.17
3.4
2.7
23.1
22.4
%
0.52
472
3961
852
7136
1.25
7.16
1.9
1.7
1.1
1.3
mg/l
1.67
625
5504
124
739
1.70
7.14
1.4
1.4
—
—
—
0
0
330
2447
1.38
6.83
3.2
2.6
10.4
10.5
g/l
0.09
296
2223
993
8502
1.22
6.73
4.6
4.1
0.0
0.0
estimate
1.34
383
2888
344
2574
1.37
6.73
4.1
4.0
102.2
92.4
ng/l
0.59
289
2217
569
4578
1.28
6.68
1.5
1.4
—
—
—
0
0
508
4028
1.30
6.67
4.5
4.3
236.5
246.9
u/l
1.08
477
3799
170
1118
1.54
6.60
3.0
2.7
—
—
—
0
0
1232
10816
1.20
6.40
4.4
4.0
11.3
9.7
mg/mmol
0.48
719
6859
384
2947
1.34
6.37
2.5
2.6
66.5
66.3
g/l
0.16
335
2687
496
3949
1.29
6.31
2.4
2.5
1.8
1.8
%
0.16
418
3505
144
922
1.58
6.30
1.9
1.8
—
—
—
0
0
21
61
3.46
6.28
1.2
1.1
—
—
—
0
0
113
683
1.67
6.23
1.7
1.3
10.7
10.1
u/l
0.18
91
568
139
897
1.57
5.90
2.0
1.6
0.2
0.2
g/l
0.80
132
848
143
930
1.56
5.87
2.0
1.5
1.2
1.2
g/l
0.66
136
879
417
3278
1.30
5.84
2.5
2.2
0.2
0.2
g/l
0.21
385
3046
1353
12058
1.18
5.81
4.3
3.9
—
—
—
0
0
107
651
1.66
5.78
1.4
1.2
—
9.2
—
0
6
1756
16024
1.17
5.60
4.1
3.7
0.0
0.0
estimate
1.06
385
2904
1734
15827
1.17
5.47
5.2
4.9
0.0
0.0
estimate
0.80
398
3004
553
4541
1.25
5.45
7.3
6.1
1.1
1.0
mmol/l
0.43
506
4215
103
633
1.64
5.38
1.4
1.2
5.0
4.2
u/ml
—
6
42
1727
15799
1.16
5.20
4.0
3.7
0.0
0.0
estimate
0.00
390
2958
175
1220
1.45
5.19
2.1
2.3
380.6
540.5
ug/l
0.64
159
1150
121
783
1.56
5.13
1.3
1.2
7.1
7.1
u/ml
0.00
19
114
192
1367
1.42
5.10
2.0
1.9
40.5
39.0
u/l
0.48
162
1198
313
2413
1.32
5.07
2.4
2.1
12.8
12.5
nmol/l
0.24
266
2121
252
1885
1.36
5.00
3.3
3.3
4.3
4.4
pmol/l
1.29
215
1658
127
837
1.53
4.97
1.3
1.2
22.4
45.7
u/ml
—
6
43
641
5400
1.22
4.97
2.2
2.1
29.8
29.9
s
0.22
620
5245
401
3204
1.28
4.97
9.5
7.4
10.6
10.2
mmol/l
0.47
365
3053
15
41
3.67
4.92
1.2
1.1
—
—
—
0
0
140
948
1.49
4.84
1.8
1.6
0.5
10.1
iu/ml
0.79
20
197
32
137
2.35
4.82
1.1
1.3
—
—
—
0
0
69
398
1.75
4.60
1.6
1.5
61.9
59.1
%
0.25
45
250
379
3038
1.27
4.58
2.4
2.3
6.7
7.6
ug/l
0.44
308
2678
143
987
1.47
4.52
1.5
1.4
278.3
268.2
ug/g
0.25
80
592
117
775
1.53
4.51
1.4
1.2
12.3
3.6
u/ml
0.40
14
71
195
1426
1.39
4.48
2.2
1.9
1.2
2.6
ug/l
1.94
157
1264
313
2462
1.29
4.40
1.6
1.7
—
—
—
0
0
241
1828
1.34
4.39
1.3
1.3
139.5
220.0
u/ml
1.67
220
1667
61
350
1.75
4.18
1.1
1.1
—
—
—
0
0
158
1129
1.42
4.17
3.0
3.4
34.8
56.3
mg/l
1.03
130
923
113
757
1.51
4.16
1.4
1.3
—
—
—
0
0
158
1132
1.41
4.12
3.0
3.4
43.7
107.1
mg/l
0.69
129
926
41
208
1.98
4.11
2.8
2.4
440.4
486.6
e6/l
0.41
34
174
59
341
1.74
3.96
1.6
1.4
22.7
27.9
u/l
0.53
49
283
66
395
1.68
3.91
1.7
1.3
—
—
—
0
0
41
213
1.93
3.86
1.0
1.1
—
—
—
0
0
152
1096
1.40
3.84
3.0
3.3
3.4
2.7
ratio
—
9
88
133
937
1.43
3.83
1.8
1.7
—
—
—
0
0
117
805
1.47
3.81
1.5
1.5
—
—
—
0
0
21
83
2.54
3.79
1.1
1.1
—
—
—
0
0
252
1967
1.30
3.79
1.6
1.5
—
—
—
0
0
121
840
1.45
3.77
2.2
2.0
10.4
11.5
mg/l
1.17
113
783
90
592
1.53
3.65
1.9
1.6
—
—
—
0
0
42
225
1.88
3.63
1.0
1.1
34.3
45.1
mg/l
1.03
34
184
432
3610
1.22
3.63
4.0
3.5
—
—
—
0
0
87
569
1.54
3.63
3.9
3.6
1.6
1.5
%
0.08
73
429
41
218
1.89
3.62
1.0
1.0
251.1
300.5
mg/l
0.91
35
186
131
932
1.42
3.59
1.4
1.3
—
—
—
0
0
113
783
1.46
3.57
1.8
1.6
—
—
—
0
0
1061
9575
1.15
3.54
4.5
4.3
22.3
22.0
%
0.26
528
4806
327
2662
1.25
3.51
2.9
2.7
56.8
64.8
ml/min/173m2
3.18
136
1062
210
1623
1.31
3.43
1.7
1.7
1.5
1.6
g/l
0.07
180
1399
653
5697
1.17
3.42
3.6
3.3
0.8
0.8
mmol/l
0.37
600
5318
114
800
1.44
3.39
1.8
1.5
—
—
—
0
0
262
2091
1.27
3.35
1.7
1.6
—
—
—
0
0
12
37
3.25
3.34
3.4
1.8
—
—
—
0
0
36
189
1.91
3.33
1.1
1.3
—
—
—
0
0
123
879
1.41
3.32
2.9
3.2
25.3
25.2
mmol/l
0.10
107
764
155
1153
1.36
3.29
1.2
1.2
1.4
1.2
u/ml
—
10
95
36
190
1.90
3.28
1.1
1.3
—
—
—
0
0
101
698
1.46
3.27
3.3
3.1
0.7
0.8
nmol/l
1.58
73
535
57
346
1.66
3.26
1.1
1.1
—
4.5
—
0
5
104
729
1.44
3.14
1.1
1.1
—
—
—
0
0
22
98
2.25
3.12
1.1
1.3
20.7
449.0
ug/l
—
9
49
118
851
1.40
3.05
3.5
3.0
1.7
1.6
mg/l
0.67
106
778
133
981
1.37
3.01
1.8
1.7
—
—
—
0
0
55
339
1.63
3.00
4.0
3.7
60.1
57.8
%
0.31
40
206
21
94
2.24
2.96
3.8
2.6
—
—
—
0
0
134
993
1.36
2.95
1.9
1.7
—
—
—
0
0
102
722
1.42
2.94
3.2
2.4
16.0
16.0
%
0.01
60
380
38
214
1.78
2.87
2.3
1.8
18.4
17.0
nmol/l
0.35
31
200
116
845
1.38
2.85
2.0
1.8
42.2
41.3
nmol/l
0.17
109
812
445
3819
1.19
2.84
1.8
1.7
—
—
—
0
0
38
216
1.77
2.79
2.8
2.3
613.3
614.6
e6/l
0.01
20
90
8
19
4.22
2.67
1.0
1.0
—
—
—
0
0
106
771
1.39
2.65
2.5
2.2
129.3
128.3
g/l
0.17
79
551
10
32
3.13
2.64
1.4
1.0
—
—
—
0
0
85
596
1.44
2.62
1.7
1.4
—
—
—
0
0
59
385
1.54
2.58
4.9
6.3
7.7
7.5
mmol/l
0.14
49
322
70
475
1.48
2.56
1.8
1.4
—
—
—
0
0
91
650
1.41
2.54
2.1
2.1
1299.3
4840.6
u/l
1.55
23
270
799
7230
1.13
2.49
3.1
2.6
4.2
5.5
e6/l
2.94
705
6321
68
462
1.48
2.48
1.8
1.5
—
—
—
0
0
112
837
1.35
2.40
1.7
1.6
13082.3
12714.6
e6/l
0.04
93
596
102
752
1.37
2.38
3.0
3.0
8.1
8.0
kpa
0.32
92
695
11
40
2.75
2.37
1.0
1.1
—
—
—
0
0
5
8
6.26
2.37
1.0
1.0
—
—
—
0
0
40
243
1.65
2.37
1.7
1.5
22.9
20.1
u/ml
—
8
47
47
298
1.58
2.35
1.0
1.0
—
—
—
0
0
75
527
1.43
2.32
1.7
1.4
—
—
—
0
0
18
85
2.12
2.28
1.8
1.6
0.5
0.4
ug/l
—
9
51
173
1384
1.26
2.26
2.1
2.2
7.3
7.4
g/l
0.56
123
1066
164
1304
1.27
2.26
2.1
2.3
3.0
3.1
g/l
0.54
115
1044
51
334
1.53
2.24
2.3
2.9
—
—
—
0
0
68
474
1.44
2.21
6.5
6.6
12.0
12.0
mg/l
0.00
62
435
51
335
1.53
2.21
1.5
1.7
—
—
—
0
0
56
376
1.50
2.20
1.9
1.6
—
—
—
0
0
27
150
1.81
2.19
2.4
3.3
19.4
25.6
mu/l
0.68
27
145
957
8813
1.11
2.19
1.7
1.6
1.3
1.4
mmol/l
0.49
796
7386
43
273
1.58
2.17
3.9
4.9
48.8
67.6
u/ml
0.33
11
68
24
129
1.87
2.16
1.2
1.3
—
—
—
0
0
28
159
1.77
2.13
1.7
2.4
92.5
97.1
%
0.33
23
151
162
1298
1.26
2.11
2.1
2.2
9.9
10.3
g/l
0.71
121
1109
171
1382
1.25
2.07
2.1
2.2
3.8
3.8
g/l
0.07
113
1024
171
1382
1.25
2.07
2.1
2.2
—
—
—
0
0
38
238
1.60
2.04
1.4
1.8
18.1
6.3
umol/l
0.60
30
167
765
6994
1.12
2.00
3.2
3.1
0.8
0.8
ug/l
0.17
519
4802
50
336
1.49
1.98
1.6
1.5
0.2
0.3
nmol/l
1.02
38
253
53
361
1.47
1.97
1.5
1.6
—
—
—
0
0
35
217
1.62
1.96
1.2
1.4
—
—
—
0
0
27
156
1.74
1.96
1.6
1.6
—
—
—
0
0
21
112
1.88
1.96
2.1
2.5
24.9
29.2
umol/l
1.10
16
78
45
297
1.52
1.95
1.3
1.2
—
—
—
0
0
12
51
2.36
1.94
1.0
1.5
—
—
—
0
0
42
273
1.54
1.94
1.9
1.5
—
—
—
0
0
118
920
1.29
1.94
1.5
1.7
—
—
—
0
0
35
218
1.61
1.93
1.2
1.4
—
—
—
0
0
23
127
1.82
1.93
1.2
1.1
2032.9
487.8
ng/l
—
8
31
6
16
3.75
1.93
1.5
1.1
—
—
—
0
0
29
172
1.69
1.92
1.2
1.4
—
—
—
0
0
29
172
1.69
1.92
1.2
1.4
—
—
—
0
0
65
464
1.41
1.90
1.7
1.4
—
—
—
0
0
150
1211
1.25
1.87
2.6
2.3
1.5
0.9
g/l
0.84
115
1050
138
1106
1.26
1.84
2.2
2.1
38.2
37.6
g/l
0.58
105
966
32
198
1.62
1.83
1.3
1.3
0.3
1.2
u/ml
0.83
21
93
5
12
4.17
1.82
1.0
1.2
—
—
—
0
0
18
94
1.92
1.80
1.1
1.1
88.7
88.4
%
—
7
52
430
3825
1.14
1.78
2.7
2.7
6.8
8.6
umol/l
1.34
371
3328
430
3825
1.14
1.78
1.9
1.7
—
—
—
0
0
227
1923
1.19
1.77
1.1
1.2
229.2
143.9
iu/ml
0.61
74
698
124
992
1.26
1.70
1.2
1.3
—
—
—
0
0
94
726
1.30
1.70
1.3
1.3
245.7
209.4
miu/ml
0.35
34
313
1133
10650
1.09
1.67
3.3
3.3
30.9
37.0
u/l
2.26
1062
10062
25
149
1.68
1.66
1.4
1.2
—
—
—
0
0
23
134
1.72
1.65
1.9
2.0
—
—
—
0
0
23
134
1.72
1.65
1.9
2.0
—
—
—
0
0
23
134
1.72
1.65
1.9
2.0
—
—
—
0
0
35
228
1.54
1.64
1.5
1.5
95.0
196.3
pmol/l
0.33
15
67
260
2245
1.17
1.64
2.0
1.9
—
—
—
0
0
236
2022
1.18
1.64
2.0
1.8
—
—
—
0
0
21
120
1.75
1.62
1.0
1.1
1858.3
1731.6
miu/ml
0.19
21
120
29
450
0.64
1.61
4.1
5.0
344.0
356.8
umol/l
0.17
23
387
35
231
1.52
1.56
1.9
2.1
20.7
13.4
%
0.75
17
99
87
675
1.30
1.54
6.2
5.3
1245.2
3020.7
iu/ml
—
10
95
15
78
1.93
1.54
1.4
1.6
—
—
—
0
0
46
324
1.42
1.51
1.2
1.4
213332.9
103959.6
e6/l
0.35
32
230
102
812
1.26
1.49
1.5
1.4
—
—
—
0
0
71
539
1.32
1.48
2.2
1.8
1.7
1.7
mmol/l
0.11
71
524
93
733
1.28
1.48
2.7
2.8
33.5
35.3
umol/l
0.26
84
616
17
94
1.81
1.47
1.1
1.3
94.3
88.9
%
—
7
53
5
16
3.13
1.44
5.4
3.8
—
—
—
0
0
16
88
1.82
1.41
1.7
1.9
0.5
1.2
ug/l
2.20
16
83
58
431
1.35
1.41
1.8
1.7
—
—
—
0
0
41
287
1.43
1.40
1.7
1.6
—
—
—
0
0
41
287
1.43
1.40
1.7
1.6
—
—
—
0
0
41
287
1.43
1.40
1.7
1.6
—
—
—
0
0
140
1166
1.21
1.37
1.8
1.8
—
—
—
0
0
30
198
1.52
1.37
1.0
1.1
1.8
8.8
nmol/l
—
7
40
9
42
2.15
1.33
1.0
1.1
—
—
—
0
0
108
1315
0.82
1.30
3.4
3.4
115.1
4089.8
u/ml
1.17
96
1122
28
185
1.52
1.28
1.8
1.6
2.6
2.3
u/field
0.06
16
136
26
169
1.54
1.28
1.8
1.8
—
—
—
0
0
26
169
1.54
1.28
1.8
1.8
—
—
—
0
0
26
169
1.54
1.28
1.7
1.8
—
—
—
0
0
26
169
1.54
1.28
1.8
1.8
—
—
—
0
0
10
48
2.09
1.27
1.0
1.1
—
—
—
0
0
174
1491
1.17
1.26
1.1
1.0
—
—
—
0
0
8
36
2.22
1.24
1.1
1.3
1.9
1.7
umol/24h
—
8
36
57
434
1.32
1.21
1.9
1.7
87.7
89.6
%
0.88
57
428
66
513
1.29
1.21
1.1
1.2
—
—
—
0
0
84
674
1.25
1.20
1.8
1.6
—
—
—
0
0
138
1624
0.84
1.18
2.6
3.8
28.8
62.2
u/ml
4.09
129
1565
126
1058
1.20
1.17
1.6
1.7
3.3
3.7
mg/l
0.18
90
749
2632
26891
0.94
1.16
20.1
18.4
13.7
13.7
%
0.35
2590
26308
10
50
2.00
1.16
9.2
14.2
4.8
5.7
mmol/l
—
10
50
15
87
1.73
1.15
1.1
1.1
—
—
—
0
0
51
386
1.33
1.15
1.1
1.0
3.9
2.5
u/ml
0.43
16
168
72
575
1.26
1.09
1.3
1.2
40.4
43.3
u/l
0.08
61
499
117
984
1.19
1.09
2.5
2.5
3.4
3.6
g/l
1.34
108
936
62
487
1.28
1.08
1.8
1.6
—
—
—
0
0
13
74
1.76
1.06
1.0
1.2
—
—
—
0
0
10
180
0.55
1.06
1.0
1.1
—
—
—
0
0
164
1423
1.16
1.06
5.0
5.4
1.8
1.6
%
0.75
157
1321
22
145
1.52
1.05
1.2
1.2
2.0
6.8
u/ml
—
5
13
20
129
1.55
1.05
1.7
1.5
—
—
—
0
0
245
2187
1.13
1.05
8.5
7.0
24.6
24.6
mmol/l
0.01
234
2023
288
3189
0.90
1.05
2.9
2.4
38.9
53.1
u/l
0.44
249
2731
28
195
1.44
1.04
1.7
1.6
5.8
7.3
u/l
0.58
21
168
38
280
1.36
1.03
1.8
1.9
1.7
2.0
u/field
0.11
12
113
9
46
1.96
1.03
1.1
1.2
—
—
—
0
0
7
35
2.00
1.00
1.0
1.4
—
—
—
0
0
315
2865
1.11
0.98
5.9
3.9
1.2
1.2
mmol/l
0.21
288
2500
41
310
1.33
0.96
1.4
1.4
—
—
—
0
0
16
247
0.65
0.95
1.1
1.0
549.6
715.5
ng/l
—
10
160
404
3727
1.09
0.95
3.7
4.1
6.2
23.1
ug/l
4.39
324
3047
32
233
1.38
0.95
2.0
2.2
—
—
—
0
0
102
862
1.19
0.93
1.2
1.3
—
—
—
0
0
9
52
1.73
0.92
1.1
1.5
107.9
148.7
ng/l
—
9
52
6
28
2.14
0.91
3.0
4.4
—
—
—
0
0
26
184
1.42
0.91
1.6
1.3
1.4
1.2
nmol/l
0.33
20
142
25
176
1.42
0.90
1.1
1.1
1.0
1.1
u/l
0.57
12
95
51
402
1.27
0.90
1.4
1.3
243.8
272.8
pmol/l
0.49
36
313
45
351
1.29
0.87
1.3
1.2
51.1
59.8
u/l
0.66
28
239
25
178
1.41
0.86
1.0
1.2
—
—
—
0
0
91
769
1.19
0.85
3.2
3.5
170.2
716.8
u/ml
0.94
77
712
50
397
1.26
0.85
1.0
1.1
—
—
—
0
0
15
96
1.56
0.84
1.1
1.2
—
—
—
0
0
1081
10386
1.06
0.82
3.8
3.3
49.9
79.7
e6/l
0.75
850
7994
8
46
1.74
0.82
2.6
2.0
—
—
—
0
0
159
1408
1.13
0.82
5.5
5.5
0.9
0.9
%
0.68
152
1312
100
856
1.17
0.82
2.5
2.4
147.1
110.7
ug/min
0.34
56
534
56
453
1.24
0.82
1.2
1.1
—
—
—
0
0
43
337
1.28
0.81
1.8
1.4
20.3
26.1
iu/ml
—
6
13
15
97
1.55
0.81
1.0
1.1
—
—
—
0
0
8
47
1.70
0.80
1.1
1.1
—
—
—
0
0
27
198
1.37
0.80
2.0
1.5
—
—
—
0
0
23
164
1.40
0.79
3.7
4.0
—
—
—
0
0
12
188
0.64
0.79
1.1
1.1
—
—
—
0
0
17
114
1.49
0.79
1.2
1.3
4.3
3.3
mmol/l
0.62
17
101
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
175
1954
0.89
0.79
10.7
9.3
24.3
24.3
mmol/l
0.03
165
1822
994
9544
1.06
0.78
3.7
3.2
0.4
0.5
e6/l
0.76
762
7202
27
200
1.35
0.76
1.1
1.0
—
—
—
0
0
27
200
1.35
0.76
2.1
1.5
—
—
—
0
0
327
3528
0.92
0.75
1.5
1.8
1.4
1.5
%
2.22
283
3062
42
525
0.80
0.74
1.1
1.1
31.0
80.7
iu/ml
—
8
119
521
5515
0.94
0.72
3.4
3.0
2.6
2.4
e6/l
0.18
283
2997
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
144
1281
1.13
0.72
3.5
3.0
0.3
0.3
u/ml
0.43
95
729
11
68
1.62
0.71
2.5
1.3
—
—
—
0
0
12
76
1.58
0.71
1.3
1.3
—
—
—
0
0
11
170
0.65
0.70
1.0
1.0
—
—
—
0
0
25
186
1.35
0.70
1.8
2.6
37.3
39.2
%
—
10
65
11
69
1.60
0.68
7.0
3.1
28.8
45.6
u/l
—
6
24
7
43
1.63
0.66
1.3
1.0
—
—
—
0
0
19
260
0.73
0.66
1.5
1.5
—
—
—
0
0
18
128
1.41
0.65
1.1
1.2
—
—
—
0
0
715
6844
1.05
0.64
4.5
4.1
1.0
1.0
kg/l
0.29
117
1057
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
5
29
1.73
0.64
1.2
1.0
—
—
—
0
0
462
4368
1.07
0.63
1.4
1.4
—
—
—
0
0
560
5884
0.94
0.63
3.1
2.8
1.0
1.1
e6/l
0.42
317
3349
47
387
1.22
0.63
1.3
1.3
8.0
7.3
mmol/l
0.83
34
283
6
102
0.59
0.62
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
21.1
—
0
20
0
20
0.00
0.60
0.0
1.1
—
8.1
—
0
20
0
20
0.00
0.60
0.0
1.1
—
37.8
—
0
20
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
12
80
1.50
0.59
2.7
2.6
—
67.8
—
0
15
13
186
0.70
0.59
1.7
2.1
194.0
285.8
ug/min
—
6
48
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
16
114
1.41
0.58
1.1
1.4
—
1308838.9
iu/ml
—
0
9
6
35
1.72
0.57
1.7
1.6
—
—
—
0
0
81
707
1.15
0.57
1.6
1.3
54.0
26.6
e6/l
0.30
65
540
81
708
1.15
0.56
1.7
1.4
3138.8
1332.7
e6/l
0.37
68
572
35
429
0.81
0.56
2.3
2.4
106.0
105.2
mmol/l
0.28
35
423
35
429
0.81
0.56
2.3
2.4
4.2
4.1
mmol/l
0.70
35
423
703
6758
1.05
0.55
4.1
3.7
261.5
543.6
ng/l
1.08
542
5449
33
267
1.24
0.53
1.8
1.6
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
101
902
1.12
0.52
1.2
1.3
—
—
—
0
0
64
555
1.16
0.51
1.4
1.4
110.4
119.4
u/ml
0.30
12
103
34
278
1.22
0.51
1.0
1.1
11.0
3.6
u/ml
0.78
13
117
48
407
1.18
0.50
1.6
1.4
94733.0
58880.1
e6/l
0.23
28
241
52
445
1.17
0.49
1.1
1.1
1.5
1.5
g/l
0.21
45
398
23
180
1.28
0.49
1.1
1.2
1.0
1.0
ratio
—
9
63
37
308
1.20
0.48
1.6
1.5
20.3
30.8
%
1.46
22
190
29
354
0.82
0.47
1.4
1.5
—
—
—
0
0
210
1959
1.08
0.46
11.0
9.9
—
—
—
0
0
22
173
1.27
0.46
1.1
1.1
—
—
—
0
0
16
210
0.76
0.46
3.3
1.6
—
—
—
0
0
52
449
1.16
0.45
1.2
1.1
1.4
1.6
u/ml
0.08
21
182
56
487
1.15
0.45
1.2
1.2
3.5
4.0
u/ml
0.23
27
206
111
1009
1.10
0.44
2.5
2.2
0.0
0.0
g/l
0.39
97
920
133
1447
0.92
0.44
1.3
1.3
—
—
—
0
0
139
1509
0.92
0.43
3.7
4.0
52.2
48.6
%
0.93
139
1491
8
58
1.38
0.41
3.0
1.6
—
—
—
0
0
5
33
1.52
0.41
1.4
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
3.2
—
0
15
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
23.9
—
0
9
27
326
0.83
0.41
1.6
1.7
—
—
—
0
0
17
132
1.29
0.40
1.1
2.5
15.0
145.7
umol/l
—
6
75
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
14
106
1.32
0.39
1.4
1.8
—
—
—
0
0
66
589
1.12
0.38
1.2
1.2
—
—
—
0
0
36
307
1.17
0.38
1.0
1.0
8.8
2.6
u/ml
0.84
17
123
19
151
1.26
0.38
2.3
2.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
321
3062
1.05
0.38
3.6
2.8
193.2
204.3
ng/l
0.20
302
2785
5
37
1.35
0.37
1.4
1.5
—
—
—
0
0
9
69
1.31
0.37
1.1
1.1
—
—
—
0
0
20
246
0.81
0.37
1.2
1.3
10.8
12.6
mmol/l
—
7
72
29
244
1.19
0.36
1.2
1.2
—
—
titre
—
0
0
17
135
1.26
0.35
1.5
1.6
1.9
8.4
nmol/l
1.21
11
116
116
1073
1.08
0.35
2.4
2.2
0.0
0.0
g/l
0.73
102
981
10
73
1.37
0.34
1.2
1.4
—
—
—
0
0
259
2466
1.05
0.34
1.8
1.8
—
—
—
0
0
60
539
1.11
0.33
1.3
1.2
—
—
—
0
0
6
86
0.70
0.33
1.0
1.1
—
—
—
0
0
103
954
1.08
0.31
2.3
2.4
186.6
197.5
%
0.65
95
903
40
352
1.14
0.31
2.9
3.5
—
—
—
0
0
107
998
1.07
0.28
2.6
2.2
0.0
0.0
g/l
0.00
97
919
29
251
1.16
0.28
2.1
1.4
0.9
1.2
promille
0.65
24
194
308
3197
0.96
0.27
4.5
3.8
5.9
5.8
kpa
0.02
300
3100
27
233
1.16
0.27
2.0
1.4
—
—
—
0
0
68
740
0.92
0.27
1.3
1.3
—
—
—
0
0
68
740
0.92
0.27
1.3
1.3
—
—
—
0
0
24
206
1.17
0.26
1.7
1.6
1.7
5.7
u/l
—
7
102
650
6355
1.03
0.25
3.0
3.2
2.5
2.5
mmol/l
0.78
575
5559
32
283
1.13
0.24
2.6
2.2
680.6
656.6
ml
0.12
21
186
10
78
1.28
0.24
1.2
1.3
—
—
—
0
0
29
255
1.14
0.24
1.1
1.0
300.2
289.8
mg/l
0.27
24
228
60
552
1.09
0.23
1.3
1.2
265.5
279.7
u/ml
0.15
32
341
13
106
1.23
0.23
1.0
1.1
—
—
—
0
0
109
1028
1.06
0.23
1.3
1.4
26.5
31.4
iu/l
0.97
96
878
20
232
0.86
0.22
1.3
1.7
—
—
—
0
0
7
92
0.76
0.22
1.3
1.8
—
—
—
0
0
251
2600
0.96
0.22
3.3
3.1
4.9
4.6
kpa
1.21
244
2513
26
229
1.14
0.21
1.3
1.2
—
—
—
0
0
49
449
1.09
0.21
1.6
1.4
2604.3
2014.4
e6/l
0.44
37
328
39
353
1.11
0.21
1.1
1.0
7.2
2.5
u/ml
0.47
11
93
88
936
0.94
0.21
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
82
769
1.07
0.21
1.7
1.5
—
—
—
0
0
10
80
1.25
0.20
1.4
1.3
—
—
—
0
0
347
3376
1.03
0.20
9.1
8.1
122.1
121.0
g/l
0.39
338
3241
13
108
1.20
0.20
2.0
1.3
4.3
4.5
umol/l
0.13
13
100
14
118
1.19
0.19
1.0
1.1
—
—
—
0
0
172
1655
1.04
0.19
5.2
4.0
24.7
24.2
mmol/l
1.33
151
1497
28
251
1.12
0.18
1.0
1.0
5.4
0.4
u/ml
—
7
73
29
261
1.11
0.18
1.1
1.1
104.0
112.7
titre
—
5
44
311
3192
0.97
0.17
4.5
3.8
1.9
2.0
mmol/l
0.08
257
2609
11
91
1.21
0.17
1.1
1.1
—
—
—
0
0
22
247
0.89
0.17
1.3
1.5
0.9
0.9
g/l
0.07
22
247
51
477
1.07
0.15
1.6
1.5
—
—
—
0
0
6
80
0.75
0.15
1.3
1.5
—
—
—
0
0
9
78
1.15
0.15
1.8
2.9
—
—
—
0
0
9
78
1.15
0.15
1.2
1.0
—
—
—
0
0
418
4099
1.02
0.15
8.2
7.3
1.3
1.1
mmol/l
0.44
332
3189
9
80
1.13
0.15
2.2
1.4
7.0
9.0
ug/l
—
9
80
31
336
0.92
0.13
4.7
3.8
76.3
46.0
u/ml
0.24
31
336
11
94
1.17
0.13
1.1
1.1
—
—
—
0
0
25
273
0.92
0.13
1.4
1.5
—
—
—
0
0
72
687
1.05
0.12
3.6
1.9
1.0
0.9
nmol/l
0.23
58
581
72
752
0.96
0.11
1.4
1.5
—
—
—
0
0
92
887
1.04
0.11
1.2
1.3
—
—
—
0
0
449
4431
1.02
0.10
8.0
7.0
104.8
104.4
mmol/l
1.10
443
4329
12
106
1.13
0.09
7.4
2.6
—
—
—
0
0
12
106
1.13
0.09
7.4
2.6
—
—
—
0
0
6
56
1.07
0.08
1.0
1.3
—
—
—
0
0
211
2073
1.02
0.08
3.6
3.2
127.5
128.7
g/l
0.31
204
2017
313
3087
1.02
0.08
7.6
7.1
1.3
1.4
mmol/l
0.47
305
2975
42
401
1.05
0.08
1.1
1.1
—
—
—
0
0
416
4115
1.01
0.07
8.1
7.3
12.3
12.3
kpa
0.01
403
3912
34
323
1.05
0.07
1.3
1.3
—
—
—
0
0
10
112
0.89
0.07
1.8
1.8
—
—
—
0
0
416
4117
1.01
0.07
8.1
7.3
5.0
5.1
kpa
2.25
401
3912
23
245
0.94
0.07
1.1
1.1
—
—
—
0
0
8
92
0.87
0.06
1.4
1.2
—
—
—
0
0
42
403
1.04
0.06
1.4
1.4
—
—
—
0
0
23
244
0.94
0.06
1.1
1.1
—
—
—
0
0
42
404
1.04
0.06
1.4
1.4
—
—
—
0
0
42
404
1.04
0.06
1.4
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
182
0.93
0.05
1.1
1.1
—
—
—
0
0
42
405
1.04
0.05
1.4
1.4
—
—
—
0
0
73
712
1.03
0.05
3.5
3.5
29.8
27.5
mg/l
0.19
35
464
92
939
0.98
0.05
1.2
1.1
—
—
—
0
0
25
238
1.05
0.05
1.0
1.2
—
—
—
0
0
17
180
0.94
0.04
1.4
1.4
—
—
—
0
0
12
111
1.08
0.04
2.2
2.0
—
—
—
0
0
78
766
1.02
0.03
1.6
1.8
3.6
4.7
iu/l
0.80
23
264
51
498
1.02
0.03
1.2
1.2
2.4
3.4
u/ml
0.36
22
162
157
1586
0.99
0.03
3.6
2.7
1.2
1.2
%
0.08
157
1574
18
171
1.05
0.03
1.1
1.2
—
—
—
0
0
19
182
1.04
0.02
1.5
1.6
—
—
—
0
0
19
182
1.04
0.02
1.5
1.6
—
—
—
0
0
1463
14652
1.00
0.02
12.3
9.7
0.0
0.0
e9/l
0.75
1253
11956
48
489
0.98
0.02
1.1
1.1
—
—
—
0
0
10
93
1.08
0.02
1.1
1.1
—
—
—
0
0
10
94
1.06
0.01
1.1
1.1
—
—
—
0
0
12
114
1.05
0.00
1.3
1.4
77.6
55.2
%
2.97
12
96
24
246
0.98
0.00
1.1
1.1
—
—
—
0
0
24
246
0.98
0.00
1.1
1.1
—
—
—
0
0
24
246
0.98
0.00
1.1
1.1
—
—
—
0
0
43
436
0.99
0.00
1.3
1.5
—
—
—
0
0
162
1626
1.00
0.00
3.4
3.5
24.9
25.4
mmol/l
0.88
157
1581
17
165
1.03
0.00
4.4
2.8
—
—
—
0
0
154
1545
1.00
0.00
3.1
2.6
0.7
0.7
%
0.04
149
1482
29
286
1.01
0.00
1.1
1.1
—
—
—
0
0
20
204
0.98
0.00
1.2
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
5
49
1.02
0.00
10.2
4.8
—
—
—
0
0
7
69
1.01
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
1.7
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
9
94
0.96
0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_HL_IDIOP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_HL_IDIOP | 0.9 [0.82, 0.99] | 0.036 |
| Birth year | 0.997 [0.99, 1.01] | 0.47 |
During the follow-up period (1.1.1998 — 31.12.2019), 1342 out of 9703 females with H8_HL_IDIOP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_HL_IDIOP | 0.86 [0.78, 0.95] | 0.003 |
| Birth year | 0.988 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 1633 out of 9777 males with H8_HL_IDIOP died.
Mortality risk
Mortality risk for people of age
years, who have H8_HL_IDIOP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.085% | 0.141% |
| 5 | 0.603% | 0.918% |
| 10 | 1.326% | 2.653% |
| 15 | 2.72% | 4.967% |
| 20 | 4.618% | 8.504% |
Relationships between endpoints
↥Index endpoint: H8_HL_IDIOP – Sudden idiopathic hearing loss
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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