No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
2982 |
4. Check minimum number of eventsNone |
2982 |
5. Include endpointsNone |
2982 |
6. Filter based on genotype QC (FinnGen only) |
2982 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Crossbite
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 107102 | 55446 | 51543 |
| Only index persons | 80238 | 41490 | 38748 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.52 | 1.59 | 1.44 |
| Only index persons | 1.50 | 1.53 | 1.48 |
| Median age at first event (years) | |||
| Whole population | 9.39 | 9.33 | 9.41 |
| Only index persons | 10.97 | 11.00 | 10.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2982 | 1875 | 1107 |
| Unadjusted period prevalence (%) | 0.58 | 0.64 | 0.49 |
| Median age at first event (years) | 20.45 | 20.44 | 20.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2263
- Matched controls
- 21925
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SBB10
NOMESCO Finland
Teeth copy
7.3
323.0
1108
2549
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
+∞
323.0
2263
*
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
6.8
233.5
683
1317
K07.14
ICD-10 Finland
Retrognaty, maxillary
58.8
217.8
259
48
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
6.2
212.3
668
1395
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
6.8
210.7
601
1101
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.5
199.6
590
1125
SAA04
NOMESCO Finland
Special inverstigation of mouth
5.9
189.7
615
1310
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.3
189.7
576
1130
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
6.0
185.5
583
1191
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
64.6
180.9
212
35
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
5.7
172.4
564
1199
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
6.3
162.8
484
906
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
5.9
159.3
499
996
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
4.2
158.2
739
2263
K07.24
ICD-10 Finland
Open bite
13.3
150.8
276
226
SAA03
NOMESCO Finland
Extended examination of mouth
3.2
146.3
1567
8982
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
4.7
144.8
570
1458
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
7.7
141.3
354
514
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
138.7
1384
7417
EEC05
NOMESCO Finland
Le Fort I osteotomy
63.0
129.2
152
25
SXC05
NOMESCO Finland
Other oral or dental procedure
4.2
127.5
575
1655
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
4.9
125.9
469
1115
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.7
122.0
477
1189
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.9
115.2
421
973
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.8
111.8
562
1756
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
5.7
110.3
350
687
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
106.6
1116
5780
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
3.9
99.8
469
1367
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
5.0
94.4
331
721
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.9
93.6
442
1287
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.8
91.1
447
1343
SAA02
NOMESCO Finland
Basic examination of mouth
3.1
86.8
1977
15074
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.3
75.0
305
764
K07.60
ICD-10 Finland
Snapping jaw
4.9
73.9
261
566
K07.10
ICD-10 Finland
Asymmetry of jaw
28.3
70.9
98
35
SJC00
NOMESCO Finland
Bracket with fixed attachment
28.5
69.6
96
34
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.4
68.3
267
641
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
3.2
65.8
389
1322
SJB60
NOMESCO Finland
External device grinding and adaptation
3.7
65.3
318
930
SAA01
NOMESCO Finland
Simple examination of mouth
2.4
62.5
1832
14054
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
18.0
61.7
98
55
WZA90
NOMESCO Finland
Other doctors statement
2.2
58.8
794
4294
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.3
57.8
324
1051
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
3.4
54.6
289
897
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
39.3
52.6
67
17
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
5.4
52.2
165
313
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
15.6
52.0
87
56
K03.64
ICD-10 Finland
Dental calculus supragingival
2.0
51.8
919
5510
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
2.0
49.0
824
4804
K00.00
ICD-10 Finland
Hypodontia
5.0
43.2
147
303
K07.13
ICD-10 Finland
Retrognaty, mandibular
4.6
42.3
154
341
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
6.9
39.7
102
148
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.7
38.7
293
1145
K05.30
ICD-10 Finland
Periodontitis complex
2.9
36.7
241
860
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
17.4
36.5
58
33
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
36.2
1381
10313
EBA00
NOMESCO Finland
Extraction of tooth
1.8
35.5
919
6061
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
12.0
35.0
65
54
WX110
NOMESCO Finland
Local anesthesy
1.8
35.0
1661
13215
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
34.3
1157
8257
EBB10
NOMESCO Finland
Insertion of dental implant
8.9
33.6
73
82
K03.66
ICD-10 Finland
Tooth plaque
2.5
33.3
300
1285
EEC02
NOMESCO Finland
Rapid expansion of maxilla
118.1
33.3
36
*
D82
ICPC
Teeth/gum disease
1.7
32.5
926
6243
SDA02
NOMESCO Finland
Parodonthologic therapy
1.8
32.1
831
5430
K02.1
ICD-10 Finland
Caries of dentine
1.7
31.5
1437
11078
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
4.2
31.4
123
293
OIKK
NOMESCO Finland
NA
2.2
31.3
360
1738
Z01.2
ICD-10 Finland
Dental examination
1.7
31.3
1204
8830
K02.0
ICD-10 Finland
Caries limited to enamel
1.9
30.7
607
3622
EB1WA
NOMESCO Finland
NA
11.8
30.6
57
48
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
44.2
29.2
36
8
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.0
29.2
74
106
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.1
29.2
397
2054
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
17.8
28.7
45
25
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.3
28.6
293
1337
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
28.6
1163
8571
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
14.8
28.6
48
32
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
4.5
28.5
105
236
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
8.1
28.1
64
78
K03.00
ICD-10 Finland
Approximal wear
3.2
27.7
153
485
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.9
26.8
474
2701
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.6
26.1
1382
10800
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
22.1
24.8
36
16
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
3.8
24.8
110
294
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
13.8
24.4
42
30
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.6
24.4
1198
9109
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.7
24.2
557
3451
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
10.5
24.1
47
44
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
3.0
24.0
148
506
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
4.9
23.8
80
164
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
23.7
635
4106
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
23.0
441
2568
EBB15
NOMESCO Finland
Insertion of dental implant abutment
10.8
22.9
44
40
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
22.7
750
5126
K07.61
ICD-10 Finland
Cracking jaw joint
4.0
22.7
93
232
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.2
22.3
241
1121
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
15.4
21.9
36
23
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.8
21.3
382
2169
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
5.9
20.4
58
98
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.6
20.3
72
157
K07.23
ICD-10 Finland
Deep bite
2.1
20.3
236
1133
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
9.6
20.1
41
42
G47.3
ICD-10 Finland
Sleep apnoea
1.9
19.7
328
1813
OIKH
NOMESCO Finland
NA
2.1
19.3
240
1182
-1
NOMESCO Finland
NA
1.5
19.1
1063
8129
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
18.8
558
3670
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
18.4
1214
9595
D19
ICPC
Teeth/gum symptom/complaint
1.6
18.2
664
4600
K06.00
ICD-10 Finland
Local gingivore traction
5.3
17.9
55
103
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
41.0
17.0
21
5
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.5
16.3
808
5963
K07.4
ICD-10 Finland
Malocclusion, unspecified
3.6
16.1
72
196
SXC03
NOMESCO Finland
Other oral or dental procedure
5.7
15.7
45
78
SJA02
NOMESCO Finland
Plan for orthodontic care
10.5
15.1
29
27
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
14.4
15.1
25
17
OIKAL
NOMESCO Finland
NA
2.3
14.4
134
580
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
6.2
14.3
38
60
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
11.6
14.3
26
22
EMAK
NOMESCO Finland
NA
2.8
14.2
95
342
SAALT
NOMESCO Finland
NA
2.5
14.0
112
450
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
13.8
383
2452
EBA10
NOMESCO Finland
Surgical removal of tooth
1.7
13.8
344
2140
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
11.6
13.8
25
21
SFA00
NOMESCO Finland
Small filling
1.8
13.4
260
1501
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
5.0
13.4
42
82
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
13.4
295
1772
OIKRE
NOMESCO Finland
NA
3.4
13.3
64
186
OIKVA
NOMESCO Finland
NA
2.1
13.3
151
718
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
13.2
649
4732
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.5
13.2
495
3407
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
7.9
13.0
29
36
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
8.3
12.9
28
33
K05.31
ICD-10 Finland
Periodontitis pronounced
2.2
12.9
137
634
KMAK
NOMESCO Finland
NA
1.4
12.6
843
6512
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.6
12.6
94
365
K01.0
ICD-10 Finland
Embedded teeth
2.7
12.4
86
319
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
4.7
12.1
40
83
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
12.0
1202
9915
H02AB09
ATC
hydrocortisone; systemic
2.7
12.0
84
314
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
4.6
11.8
40
85
R06.5
ICD-10 Finland
Mouth breathing
1.9
11.6
168
880
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
14.3
11.6
19
13
SPA02
NOMESCO Finland
Preparation for dental prosthetics
4.1
11.4
43
102
K03.09
ICD-10 Finland
Abrasion of the teeth UNS
5.8
11.3
31
52
A98
ICPC
Health maint/preventive medicine
2.8
11.3
2227
20978
K03.11
ICD-10 Finland
Abrasion dentifrice of teeth
3.7
11.3
49
132
SPB10
NOMESCO Finland
Production of temporary crone to tooth
8.4
11.2
24
28
K06.01
ICD-10 Finland
General gingival retraction
9.8
11.2
22
22
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.2
11.1
58
180
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.6
11.1
286
1788
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
11.1
317
2038
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
11.0
167
889
Q35.1
ICD-10 Finland
Cleft hard palate
10.8
10.8
20
18
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
9.8
10.8
21
21
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
10.6
393
2682
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.3
10.5
96
415
ZXA10
NOMESCO Finland
Bilateral
1.6
10.5
313
2034
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
9.9
174
974
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
9.7
352
2390
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
3.3
9.6
46
135
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.5
9.6
44
125
127
Kela drug reimbursment
Transplant complication
3.3
9.6
47
141
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
9.5
438
3124
BE00A
NOMESCO Finland
NA
14.6
9.3
15
10
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.6
9.3
66
249
4361
FHL
Lip plastic or reconstruction due to cleft lip
97.3
9.3
10
*
SPC01
NOMESCO Finland
Fixed dental crown
4.7
9.3
30
62
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
2.9
9.2
54
183
R01AD09
ATC
mometasone; nasal
1.3
9.1
836
6700
OIKJA
NOMESCO Finland
NA
3.0
9.1
52
171
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
9.1
1130
9460
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
1.9
9.1
132
692
L17
ICPC
Foot/toe symptom/complaint
1.4
9.1
532
3964
J34.2
ICD-10 Finland
Deviated nasal septum
2.1
9.0
95
438
SPF40
NOMESCO Finland
Removal and reattachment with cement of tooth crone or short bridge
3.9
9.0
35
87
WX290
NOMESCO Finland
Other blockade of nerve
1.3
8.9
1023
8462
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
35.7
8.9
11
*
R01AD12
ATC
fluticasone furoate; nasal
1.4
8.8
623
4788
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
8.8
583
4434
R51.80
ICD-10 Finland
Headache
1.5
8.8
330
2258
UDC00
NOMESCO Finland
Ear microscopy
1.8
8.7
158
895
SPAT1301
SPAT
No procedures
1.4
8.7
624
4809
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
10.4
8.6
16
15
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
8.6
376
2650
ECB17
NOMESCO Finland
Operation for cleft gingiva
48.6
8.6
10
*
602
Kela drug reimbursment
Children's severe malnutrition
3.0
8.5
47
154
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.2
8.5
25
47
K07.32
ICD-10 Finland
Displacement of tooth or teeth
5.5
8.5
24
43
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.3
455
3344
EEC99
NOMESCO Finland
Other reconstructive operations on maxilla
87.6
8.3
9
*
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
4.6
8.3
27
57
N03AX16
ATC
pregabalin; oral
1.5
8.2
297
2015
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
4.7
8.1
26
54
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.3
8.1
28
63
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
14.1
8.0
13
9
G50.1
ICD-10 Finland
Atypical facial pain
3.8
7.9
32
83
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.6
7.9
181
1099
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
5.0
7.9
24
47
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.0
7.9
24
47
Z29.8
ICD-10 Finland
Other specified prophylactic measures
2.1
7.8
85
403
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
4.5
7.7
26
57
Z13.88
ICD-10 Finland
Special screening examination for other specified diseases and disorders
1.7
7.7
149
860
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.6
7.7
197
1231
Z94.0
ICD-10 Finland
Kidney transplant status
3.3
7.7
36
106
K07.28
ICD-10 Finland
Another anomaly in the relationship between the dental arches
10.5
7.6
14
13
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
43.7
7.6
9
*
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
3.9
7.6
29
72
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
7.5
169
1022
EB1TW
NOMESCO Finland
3D modelling of dentition
17.8
7.5
11
6
SJC20
NOMESCO Finland
Extraoral ofthodontisk pulling device arrangement and urser information
2.6
7.3
52
200
OIKKK
NOMESCO Finland
NA
3.8
7.3
29
75
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
+∞
7.2
7
*
K07.33
ICD-10 Finland
Crowding of tooth or teeth
4.3
7.2
25
57
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
8.1
7.1
15
18
SPAT1058
SPAT
PEF monitoring instruction
1.7
7.1
139
808
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
9.1
7.1
14
15
SPA05
NOMESCO Finland
Guiding rail
15.3
7.1
11
7
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
7.1
256
1733
SPAT1263
SPAT
Sampling
1.3
7.0
868
7175
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
7.1
7.0
16
22
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
7.0
164
1004
ECA00
NOMESCO Finland
Surgical exposure of tooth
3.0
7.0
37
120
M79.1
ICD-10 Finland
Myalgia
1.5
7.0
215
1409
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.6
7.0
179
1122
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
7.0
137
797
XX7LW
NOMESCO Finland
NA
11.7
6.9
12
10
F43.8
ICD-10 Finland
Other reactions to severe stress
2.4
6.9
53
215
H01
ICPC
Ear pain/earache
1.4
6.8
323
2309
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.4
6.8
31
90
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
6.1
6.8
17
27
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
6.7
60
260
DHB50
NOMESCO Finland
Turbinoplasty
2.4
6.7
52
211
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
6.7
95
496
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
4.5
6.7
22
48
EAB30
NOMESCO Finland
Correction of cleft lip
38.8
6.7
8
*
ECA70
NOMESCO Finland
Regenerative parodontal operation or gingiva and alveolus transplantation
10.6
6.7
12
11
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.7
6.6
21
44
H02AB04
ATC
methylprednisolone; systemic
1.6
6.6
180
1144
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
2.5
6.6
50
200
4364
FHL
Pharyngeal tongue plastic
21.9
6.6
9
*
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
2.7
6.5
43
159
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
6.5
409
3070
FM2CE
NOMESCO Finland
NA
2.2
6.5
63
284
A02BC05
ATC
esomeprazole; systemic
1.3
6.5
523
4077
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.4
278
1950
E0000UV
ATC
NA
1.3
6.4
788
6487
ECA50
NOMESCO Finland
Parodontal operation
5.0
6.4
19
37
R4110
NOMESCO Finland
Physiotherapy
1.4
6.4
399
2988
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
6.3
247
1700
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
67.9
6.3
7
*
EDC30
NOMESCO Finland
Genioplasty
67.9
6.3
7
*
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
67.9
6.3
7
*
N06AA09
ATC
amitriptyline; systemic
1.8
6.3
102
561
XQ800
NOMESCO Finland
Prick test
1.5
6.3
184
1187
A02BC01
ATC
omeprazole; systemic
1.4
6.3
345
2530
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
6.3
129
761
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
13.9
6.3
10
7
L04AX01
ATC
azathioprine; systemic
1.9
6.2
84
435
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.2
593
4725
4368
FHL
Closing the fistula of the mouth
+∞
6.2
6
*
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.2
228
1552
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
6.1
673
5461
HAMTE
NOMESCO Finland
NA
4.1
6.1
22
53
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.2
6.1
58
260
UDM02
NOMESCO Finland
Sinoscopy
2.7
6.1
37
132
SJC04
NOMESCO Finland
NA
3.7
6.0
24
63
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
122
446
2.60
20.49
3.3
3.1
31.4
21.8
mu/l
0.64
115
414
39
80
4.57
16.12
5.1
5.0
—
—
—
0
0
1101
8280
1.37
14.38
3.6
2.5
73.9
71.4
nmol/l
2.29
1011
7710
1170
8909
1.36
14.03
10.6
7.4
1.2
1.2
mmol/l
2.19
1014
7785
333
2007
1.61
13.51
5.9
4.5
1.5
1.6
%
0.49
300
1853
451
2913
1.51
13.47
13.0
7.5
1.2
1.2
mmol/l
1.06
424
2760
233
1285
1.74
13.26
2.0
1.9
7.1
7.1
u/l
0.01
177
963
1795
14689
1.34
12.89
4.9
3.9
8.9
9.0
mm/h
0.08
1668
13656
36
85
3.96
12.50
9.4
8.2
2.0
2.8
mg/l
1.56
30
68
104
447
2.20
12.31
9.3
6.9
378.9
914.1
u/ml
—
7
44
36
86
3.92
12.30
7.6
9.5
—
—
—
0
0
348
2203
1.53
11.33
2.9
2.3
335.1
364.9
nmol/l
2.37
321
2069
2265
19371
1.37
11.13
4.9
4.3
1.9
2.1
mu/l
1.00
2091
18168
188
1026
1.75
11.11
21.9
12.6
1.2
1.1
mg/l
0.07
182
991
2005
16850
1.33
10.94
4.3
3.7
14.4
14.5
pmol/l
0.34
1801
15333
114
534
2.02
10.83
9.9
7.3
264.7
331.3
iu/ml
0.24
15
63
28
61
4.29
10.81
6.9
6.3
—
—
—
0
0
28
61
4.29
10.81
6.0
6.3
—
—
—
0
0
246
1472
1.60
10.24
1.9
1.8
15.9
18.1
iu/l
0.61
189
1145
380
2500
1.47
10.22
11.2
6.4
1.6
1.6
mmol/l
0.08
335
1993
48
157
2.86
10.12
40.2
29.6
140.7
133.4
ug/l
0.22
43
141
381
2514
1.47
10.09
11.1
6.3
5.9
5.9
kpa
0.17
375
2436
1053
8183
1.30
9.97
11.7
7.2
1.2
1.2
mmol/l
0.90
960
7580
349
2269
1.48
9.96
11.6
6.1
5.0
4.9
kpa
0.49
342
2203
1376
11080
1.29
9.87
8.9
6.5
52.8
53.8
%
2.35
1293
10478
25
54
4.32
9.77
8.4
7.4
—
—
—
0
0
1393
11258
1.28
9.60
9.2
6.7
32.0
31.6
%
0.75
1310
10611
226
1347
1.60
9.57
9.3
5.3
69.0
68.3
ng/l
0.06
207
1259
69
279
2.32
9.51
3.6
3.2
—
—
—
0
0
1336
10760
1.28
9.39
9.4
6.7
3.1
2.9
%
1.81
1252
10124
256
1581
1.55
9.30
2.7
2.2
11.5
11.2
nmol/l
0.19
220
1385
28
70
3.73
9.05
1.7
1.6
17.9
17.6
nmol/l
—
9
22
69
293
2.21
8.52
3.5
3.1
10.4
9.9
%
0.18
56
222
311
2052
1.45
8.20
8.6
6.2
1.1
1.2
mmol/l
0.08
216
1441
66
283
2.19
7.98
3.4
3.3
0.2
0.2
e9/l
1.20
51
227
314
2087
1.44
7.96
8.7
6.2
5.1
5.1
kpa
0.24
297
1990
1663
13946
1.24
7.55
7.0
6.5
89.9
85.6
u/l
2.24
1540
13157
369
2548
1.39
7.54
3.1
2.6
2.5
2.5
g/l
0.45
349
2385
65
288
2.12
7.27
3.5
3.3
541.7
535.5
e6/l
0.03
50
226
1526
12734
1.23
7.01
11.1
8.9
3.6
3.8
e9/l
2.14
1312
11007
469
3403
1.33
6.96
1.4
1.4
19.8
19.9
nmol/l
0.03
390
3002
231
1494
1.47
6.76
9.7
6.8
10.2
9.7
kpa
3.25
219
1428
398
2833
1.35
6.71
3.2
2.6
14.2
14.3
umol/l
0.07
373
2665
93
481
1.82
6.70
4.2
6.5
1.8
1.6
%
0.85
87
446
422
3032
1.34
6.68
5.3
3.4
685.6
852.1
ng/l
0.56
338
2481
316
2170
1.39
6.66
18.6
9.8
25.1
24.8
mmol/l
1.20
316
2164
17
37
4.28
6.62
2.2
2.1
—
—
—
0
0
1281
10555
1.22
6.45
3.4
2.9
75.5
80.7
ug/l
0.51
1210
9940
335
2339
1.37
6.38
3.4
2.7
23.2
23.5
%
0.14
298
2088
884
7016
1.24
6.34
7.1
5.5
37.3
37.2
g/l
0.26
823
6586
52
226
2.15
6.16
1.8
2.1
0.1
0.1
nmol/l
0.15
38
178
590
4484
1.28
6.13
1.8
1.7
1.3
1.4
mmol/l
0.83
508
3942
2450
21670
1.30
6.11
15.6
11.6
39.6
40.1
%
2.59
1941
17880
259
1748
1.41
6.05
4.2
3.5
32.5
32.0
%
0.27
177
1282
146
880
1.57
5.98
9.0
4.7
3.1
3.2
g/l
0.53
140
847
53
237
2.09
5.86
4.2
3.0
1.6
1.7
umol/l
0.82
53
229
989
8017
1.22
5.65
1.9
1.9
—
—
—
0
0
154
958
1.52
5.50
3.9
3.6
131.5
141.7
ng/l
0.11
135
848
490
3687
1.28
5.48
3.5
2.8
1926.3
3892.0
umol/l
1.09
440
3315
385
2807
1.31
5.48
12.2
5.7
0.8
0.8
mmol/l
0.04
359
2669
1306
10899
1.20
5.44
6.8
4.9
6.1
6.3
mmol/l
3.15
1192
10065
264
1824
1.38
5.38
16.0
9.8
6.7
6.6
mmol/l
0.16
256
1773
283
1985
1.36
5.25
1.6
1.3
398.7
250.3
u/ml
0.64
267
1842
645
5049
1.24
5.10
3.2
2.5
2.7
2.7
mg/l
0.03
569
4412
528
4049
1.25
5.02
3.5
2.3
1.5
1.1
mg/l
0.60
367
2901
886
7173
1.21
5.01
1.5
1.5
1.8
2.1
u/ml
0.26
170
1700
2456
21849
1.26
4.98
12.6
10.4
20.7
21.4
mg/l
0.45
1810
15937
44
197
2.09
4.90
6.1
4.8
1.2
1.7
ug/l
1.15
44
191
18
53
3.16
4.65
1.6
1.5
—
—
—
0
0
113
684
1.55
4.62
2.5
1.8
99.2
96.6
u/ml
0.06
11
95
202
1375
1.39
4.54
3.3
3.2
4.8
4.8
pmol/l
0.08
181
1250
393
2947
1.27
4.50
1.5
1.5
128000431.3
25059257.4
pmol/l
1.05
325
2550
92
536
1.61
4.43
1.4
1.5
0.3
0.3
nmol/l
0.16
68
432
173
1155
1.41
4.36
1.2
1.2
2.2
3.0
u/ml
0.49
107
641
661
5264
1.21
4.35
2.9
2.8
35.4
38.4
ng/l
0.13
354
2746
156
1026
1.43
4.27
1.1
1.1
1.3
1.4
u/ml
0.05
105
603
2320
20596
1.22
4.25
14.5
11.2
139.7
139.6
mmol/l
0.29
2251
19981
753
6086
1.20
4.22
1.9
1.7
100.2
96.7
pmol/l
1.28
377
3268
2321
20642
1.21
3.97
14.6
11.2
3.9
3.9
mmol/l
0.30
2232
19969
280
2053
1.29
3.84
1.1
1.1
—
—
—
0
0
157
1056
1.40
3.83
1.2
1.1
7.6
7.2
u/ml
0.11
111
695
18
60
2.79
3.82
3.2
1.7
—
—
—
0
0
151
1010
1.41
3.80
1.2
1.1
2.2
3.4
u/ml
0.82
45
307
249
1802
1.31
3.77
4.7
5.0
—
—
—
0
0
236
1696
1.32
3.76
4.2
4.9
243.4
251.2
u/l
0.30
224
1624
1039
8705
1.16
3.70
4.2
3.8
—
—
—
0
0
472
3696
1.22
3.65
3.3
2.9
92.4
112.8
ug/g
1.05
364
2921
2222
19728
1.18
3.64
3.6
3.6
—
—
—
0
0
51
270
1.76
3.57
2.1
1.7
—
—
—
0
0
87
530
1.54
3.54
5.2
2.9
9.0
6.6
umol/l
0.66
72
421
682
5552
1.18
3.44
3.1
3.0
2.4
2.4
mmol/l
0.24
593
5012
789
6502
1.17
3.43
4.2
3.5
29.7
31.0
u/l
0.70
762
6208
50
270
1.73
3.29
1.9
1.9
—
—
—
0
0
119
790
1.41
3.18
10.5
5.3
1.1
1.3
%
2.28
119
785
2196
19552
1.17
3.14
16.4
13.0
13.3
13.3
%
0.88
2155
19095
2745
24968
1.32
3.13
18.8
15.2
262.8
262.4
e9/l
0.13
2643
24175
286
2163
1.25
3.08
1.7
1.6
1133.8
1158.9
nmol/l
0.19
214
1702
46
250
1.72
2.99
3.2
3.0
546.5
761.5
e6/l
—
8
59
1035
8775
1.14
2.99
7.3
5.9
11.3
11.3
umol/l
0.05
960
8186
2745
24997
1.30
2.84
18.8
15.2
4.6
4.6
e12/l
0.71
2634
24132
1151
9857
1.14
2.81
3.8
3.2
0.0
0.0
estimate
0.13
195
1835
288
2204
1.23
2.80
7.2
3.9
6.5
6.8
umol/l
0.11
255
1872
2746
25014
1.30
2.77
18.8
15.2
6.7
6.7
e9/l
0.01
2639
24166
2745
25014
1.29
2.67
19.1
15.3
135.7
136.0
g/l
0.54
2691
24649
47
267
1.64
2.63
2.2
1.5
—
—
—
0
0
28
136
1.92
2.63
2.1
2.4
105.5
105.9
mmol/l
0.14
28
136
15
56
2.49
2.63
1.9
1.9
0.6
1.7
mg/l
0.78
15
40
15
56
2.49
2.63
1.9
1.9
0.9
1.1
mg/l
0.15
15
37
68
422
1.51
2.62
1.7
1.4
—
—
—
0
0
1139
9783
1.13
2.61
3.7
3.2
0.0
0.0
estimate
0.00
188
1819
157
1127
1.31
2.60
1.7
1.7
—
—
—
0
0
28
138
1.89
2.53
2.1
2.3
3.9
4.0
mmol/l
0.43
28
138
73
466
1.46
2.47
1.5
1.3
—
—
—
0
0
73
466
1.46
2.47
1.5
1.3
—
—
—
0
0
255
1955
1.23
2.46
4.6
3.4
0.2
0.2
g/l
0.09
237
1854
15
58
2.40
2.46
2.9
2.4
24.6
32.3
umol/l
—
9
44
1760
15548
1.12
2.44
5.0
4.3
37.4
37.9
mmol/mol
2.09
1623
14633
63
392
1.50
2.42
1.3
1.4
—
—
—
0
0
1136
9789
1.12
2.42
5.4
4.4
0.0
0.0
estimate
0.50
198
1900
656
5462
1.15
2.40
2.7
2.5
54.0
56.9
u/l
1.54
594
5076
36
196
1.71
2.38
2.7
2.0
19.0
20.8
umol/l
0.18
36
189
387
3098
1.18
2.37
1.3
1.2
13.9
9.3
u/ml
0.31
150
1182
651
5427
1.14
2.34
4.4
3.5
8.2
8.5
mmol/l
0.72
556
4817
1478
12953
1.12
2.30
4.3
3.8
3899.5
559.4
e6/l
0.67
19
161
52
315
1.54
2.28
1.8
1.4
4.9
5.3
umol/l
0.37
46
293
79
521
1.42
2.28
2.0
1.8
—
—
—
0
0
161
1860
0.79
2.22
1.4
1.5
—
—
—
0
0
78
517
1.41
2.20
1.9
1.9
—
—
—
0
0
537
4439
1.15
2.18
3.0
2.4
—
—
—
0
0
59
372
1.48
2.16
1.8
1.9
—
—
—
0
0
109
766
1.33
2.15
17.7
12.0
—
—
—
0
0
2433
21996
1.15
2.13
10.5
8.6
26.2
26.3
u/l
0.08
2324
21289
96
665
1.35
2.09
1.1
1.1
7.0
7.9
u/ml
0.15
56
351
5
9
5.16
2.08
1.0
1.1
—
—
—
0
0
14
57
2.28
2.08
3.9
2.7
—
—
—
0
0
132
958
1.29
2.08
2.2
1.5
—
—
—
0
0
60
384
1.46
2.06
2.7
2.1
—
—
—
0
0
62
400
1.45
2.04
1.6
1.5
13.9
17.0
u/l
0.51
53
348
406
3305
1.16
2.04
1.3
1.3
17.3
26.8
iu/ml
2.39
116
914
242
1885
1.21
2.04
3.8
3.0
9.9
10.2
g/l
0.63
226
1761
13
53
2.28
1.93
2.2
2.5
—
—
—
0
0
190
1455
1.22
1.91
1.8
1.6
332.0
337.6
mu/l
0.07
174
1312
127
929
1.28
1.90
2.3
1.6
179.7
199.5
u/ml
0.42
67
476
7
20
3.25
1.89
2.3
1.3
—
—
—
0
0
391
3193
1.16
1.89
3.7
2.9
4.2
3.3
e6/l
0.63
219
1689
44
270
1.52
1.87
4.2
3.2
1.1
1.2
%
0.13
35
223
36
211
1.59
1.86
1.9
1.3
0.6
0.5
u/ml
0.08
16
63
71
479
1.38
1.85
1.2
1.2
—
—
—
0
0
65
827
0.72
1.85
1.4
1.5
—
—
—
0
0
20
99
1.88
1.85
1.2
1.2
—
—
—
0
0
133
983
1.27
1.84
2.4
2.8
66.6
67.0
g/l
0.29
120
922
78
535
1.36
1.84
1.2
1.1
—
—
—
0
0
54
347
1.45
1.84
1.7
1.8
—
—
—
0
0
108
778
1.30
1.83
1.3
1.2
0.4
0.8
u/ml
—
8
59
158
1193
1.24
1.83
5.7
3.7
1.2
1.2
mmol/l
0.25
138
1044
15
267
0.52
1.80
1.6
1.7
7.6
7.2
mmol/l
—
9
159
57
372
1.43
1.80
2.6
2.6
—
—
—
0
0
191
2112
0.83
1.79
1.5
1.5
—
—
—
0
0
16
74
2.01
1.78
1.6
1.4
—
—
—
0
0
102
733
1.30
1.77
2.2
1.9
43.9
39.8
u/l
1.17
92
678
76
525
1.35
1.74
1.7
1.4
5.5
5.4
ug/l
0.02
70
489
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
59
392
1.40
1.71
20.3
8.7
0.4
0.3
u/ml
0.12
32
221
51
330
1.44
1.70
1.1
1.1
3.4
7.8
iu/ml
—
8
67
398
3282
1.14
1.69
3.6
2.8
1.1
1.0
e6/l
0.18
226
1774
1954
17531
1.10
1.64
3.9
3.4
5.6
5.6
mmol/l
1.89
1787
16222
202
1590
1.19
1.57
16.2
8.6
1.4
1.3
mmol/l
0.57
187
1495
334
2741
1.15
1.54
7.1
3.4
30.0
30.0
s
0.07
327
2681
15
72
1.94
1.54
1.7
1.4
—
—
—
0
0
0
40
0.00
1.53
0.0
1.1
—
—
—
0
0
134
1017
1.23
1.52
1.4
1.3
—
—
—
0
0
78
554
1.31
1.51
1.1
1.1
—
—
—
0
0
5
14
3.31
1.50
2.2
1.7
66.6
84.6
ng/l
—
5
14
16
80
1.86
1.47
1.2
1.2
46.5
40.8
u/ml
—
7
12
247
1992
1.16
1.45
1.3
1.2
138.2
144.5
iu/ml
0.08
93
696
229
1838
1.17
1.44
1.9
1.8
—
—
—
0
0
87
636
1.28
1.39
1.4
2.1
—
—
—
0
0
24
139
1.61
1.36
1.1
1.1
1.1
1.0
ratio
—
6
61
224
1805
1.16
1.35
1.9
1.7
—
—
—
0
0
5
16
2.90
1.32
6.6
2.7
—
—
—
0
0
81
593
1.27
1.29
1.4
2.1
1.4
1.3
g/l
0.19
66
521
9
40
2.09
1.29
9.9
4.6
—
—
—
0
0
97
727
1.24
1.28
1.1
1.1
4.8
6.0
u/ml
0.35
57
357
5
17
2.73
1.25
1.0
1.1
—
—
—
0
0
47
320
1.37
1.25
1.1
1.2
—
—
—
0
0
1505
13453
1.08
1.20
4.5
3.2
35.1
37.7
u/l
0.92
1413
12795
112
860
1.22
1.19
1.1
1.1
1.5
6.9
u/ml
2.12
12
113
155
1227
1.18
1.19
2.5
2.5
77.0
78.7
ml/min/173m2
0.17
54
439
6
24
2.32
1.18
1.7
3.4
24.7
3488.1
u/l
—
6
24
12
59
1.89
1.18
1.0
1.1
—
—
—
0
0
74
859
0.79
1.18
1.8
1.7
—
—
—
0
0
523
4481
1.10
1.18
2.8
2.2
300.4
236.5
u/l
0.37
489
4278
71
519
1.27
1.17
1.3
1.3
2.6
18.8
u/ml
—
9
77
183
1471
1.16
1.17
12.8
9.2
0.9
0.7
mmol/l
0.27
148
1168
65
470
1.29
1.17
1.6
1.6
—
—
—
0
0
184
1480
1.16
1.17
12.7
9.1
14.5
13.5
kpa
1.38
175
1428
69
503
1.28
1.16
1.4
1.4
319.4
320.1
ug/g
0.01
40
259
467
3982
1.10
1.16
3.6
2.8
5.6
7.2
e6/l
2.06
418
3484
184
1481
1.16
1.16
12.7
9.1
5.1
5.1
kpa
0.04
175
1426
37
246
1.40
1.14
1.4
1.2
—
—
—
0
0
855
7494
1.08
1.14
3.7
3.1
—
—
—
0
0
70
513
1.27
1.14
1.3
1.2
9.1
11.2
u/ml
—
6
52
316
2645
1.12
1.12
2.0
1.8
—
—
—
0
0
37
468
0.73
1.11
1.2
1.2
—
—
—
0
0
48
335
1.33
1.11
1.4
1.4
—
—
—
0
0
21
125
1.56
1.10
1.4
1.2
84.6
90.5
%
0.26
14
63
25
155
1.50
1.10
4.4
3.2
54.1
54.3
%
0.01
16
105
27
171
1.47
1.08
1.4
1.7
64.5
51.0
%
0.98
17
117
81
920
0.81
1.08
1.5
1.6
—
—
—
0
0
21
126
1.55
1.07
1.2
1.1
88.1
93.3
%
0.48
14
62
7
30
2.17
1.07
1.4
1.8
—
—
—
0
0
22
134
1.53
1.06
4.6
2.1
35.2
83.7
ug/l
0.36
22
116
95
731
1.21
1.02
5.8
7.9
25.0
24.4
mmol/l
0.98
87
684
624
5433
1.08
0.99
4.3
3.2
0.2
0.3
e6/l
4.76
488
4007
594
5162
1.08
0.98
3.8
3.4
0.0
0.0
estimate
0.10
191
1841
21
129
1.51
0.98
4.3
3.0
—
—
—
0
0
21
129
1.51
0.98
4.3
3.0
—
—
—
0
0
55
400
1.28
0.98
3.3
3.1
24.9
24.8
mg/l
0.00
37
254
55
400
1.28
0.98
1.2
1.3
—
4.5
—
0
27
52
376
1.29
0.97
2.8
1.8
—
—
—
0
0
15
85
1.64
0.97
1.2
1.6
—
—
—
0
0
0
29
0.00
0.96
0.0
1.2
—
—
—
0
0
127
1011
1.17
0.96
2.1
2.1
14.2
7.5
ug/l
0.80
108
896
11
57
1.79
0.95
1.1
1.0
—
—
—
0
0
32
216
1.38
0.94
1.5
1.5
—
—
—
0
0
33
224
1.37
0.94
1.6
1.5
—
—
—
0
0
1944
17615
1.07
0.94
4.2
3.6
4.6
4.6
mmol/l
1.56
1806
16669
59
436
1.26
0.94
3.7
3.6
3.5
3.8
e9/l
0.61
59
436
135
1086
1.16
0.90
1.2
1.3
192.4
225.0
miu/ml
0.60
57
528
15
87
1.60
0.90
3.6
2.1
5.2
2.2
nmol/l
0.47
15
80
19
117
1.51
0.89
1.2
1.7
25.7
38.5
%
0.88
12
76
127
1019
1.16
0.88
1.2
1.2
—
—
—
0
0
32
219
1.36
0.88
1.6
1.5
—
—
—
0
0
76
584
1.21
0.87
1.1
1.1
1.2
0.4
u/ml
0.45
28
184
529
4602
1.08
0.86
3.8
3.1
1.0
1.0
kg/l
0.11
87
650
40
285
1.30
0.85
1.7
1.3
—
103.3
—
0
6
16
96
1.55
0.85
1.5
1.2
—
—
—
0
0
381
3802
0.92
0.84
2.1
2.2
—
—
—
0
0
17
104
1.52
0.83
1.0
1.4
—
76.3
%
—
0
12
87
683
1.19
0.81
1.1
1.1
31.9
11.7
au/ml
—
6
40
0
23
0.00
0.79
0.0
1.2
—
—
—
0
0
59
447
1.23
0.79
4.1
4.0
53.1
54.4
%
0.34
59
447
31
216
1.33
0.78
1.5
1.5
—
—
—
0
0
17
228
0.69
0.77
1.1
1.4
11.3
11.7
mmol/l
—
6
54
332
3319
0.92
0.77
1.8
1.7
1.4
1.4
%
0.01
306
3003
31
217
1.33
0.76
1.5
1.5
—
—
—
0
0
107
861
1.16
0.75
2.0
1.9
—
—
—
0
0
17
226
0.70
0.74
1.1
1.1
—
—
—
0
0
9
50
1.67
0.74
1.4
1.2
—
—
—
0
0
24
162
1.38
0.74
11.8
11.1
0.6
0.6
mmol/l
0.28
24
152
33
235
1.30
0.73
1.4
1.5
—
—
—
0
0
112
1185
0.87
0.73
2.1
1.9
—
—
—
0
0
21
139
1.40
0.72
1.2
1.6
—
—
—
0
0
14
85
1.53
0.72
4.4
6.9
1.2
1.2
mmol/l
0.25
14
77
51
385
1.23
0.72
1.1
1.1
—
—
—
0
0
328
2825
1.09
0.71
4.4
3.2
1130.0
605.0
ng/l
0.46
198
1691
31
220
1.31
0.71
1.6
1.5
—
—
—
0
0
19
124
1.42
0.71
1.7
1.3
—
—
—
0
0
174
1454
1.12
0.70
2.8
2.7
—
—
—
0
0
61
471
1.20
0.70
3.4
3.2
34.5
33.5
umol/l
0.17
55
418
25
172
1.35
0.70
1.1
1.4
—
—
—
0
0
46
345
1.24
0.69
1.7
1.7
7575.0
10714.9
e6/l
0.78
32
260
107
868
1.15
0.69
2.8
2.6
27.8
41.2
u/ml
0.98
101
837
88
942
0.86
0.69
1.3
1.5
—
—
—
0
0
19
125
1.41
0.68
1.1
1.2
—
—
—
0
0
16
102
1.46
0.67
1.2
1.3
—
—
—
0
0
121
993
1.13
0.66
1.4
1.5
—
—
—
0
0
96
776
1.15
0.66
1.5
1.7
1.2
1.2
g/l
1.14
89
742
22
150
1.36
0.66
1.2
1.2
—
—
—
0
0
45
341
1.23
0.63
1.4
1.5
—
—
—
0
0
49
376
1.21
0.62
1.2
1.3
2.1
4.6
u/ml
2.79
20
179
24
290
0.77
0.61
1.9
2.4
67.1
130.8
ug/min
—
9
183
46
352
1.21
0.60
1.3
1.2
7.7
9.5
u/ml
0.09
27
174
12
162
0.69
0.59
1.4
2.0
—
—
—
0
0
10
140
0.66
0.59
1.0
1.1
1285.7
1624.9
miu/ml
—
10
140
0
21
0.00
0.59
0.0
1.3
—
—
—
0
0
33
244
1.26
0.58
1.3
1.7
—
—
—
0
0
1846
17396
0.95
0.58
9.6
8.8
95.7
95.6
ml/min/173m2
0.02
1377
13251
11
67
1.52
0.57
1.0
1.0
—
—
—
0
0
146
1227
1.11
0.56
12.2
9.7
124.0
122.7
g/l
0.34
137
1188
37
280
1.23
0.55
1.7
1.7
—
—
—
0
0
331
2889
1.07
0.54
4.5
3.9
1.9
1.9
ug/l
0.01
293
2644
23
164
1.30
0.54
1.4
1.1
323.5
112.7
u/l
0.46
15
116
22
156
1.31
0.54
1.3
1.3
95.8
257.8
pmol/l
—
8
44
6
36
1.55
0.53
1.0
2.3
—
—
—
0
0
15
100
1.39
0.53
1.0
1.2
—
—
—
0
0
15
100
1.39
0.53
1.8
1.6
—
—
—
0
0
16
199
0.74
0.52
2.1
4.0
112.3
291.7
u/ml
0.54
16
187
9
126
0.66
0.51
5.2
2.3
—
—
—
0
0
6
37
1.50
0.51
1.0
1.1
—
—
—
0
0
117
1199
0.90
0.51
1.4
1.4
—
—
—
0
0
43
473
0.84
0.51
1.2
1.1
38.5
1068.8
iu/ml
0.61
11
141
17
117
1.35
0.50
1.3
1.7
—
—
—
0
0
32
241
1.23
0.50
1.2
1.3
—
0.4
nmol/l
—
0
11
13
166
0.72
0.50
15.0
14.1
585.8
803.5
nmol/l
1.49
13
161
13
166
0.72
0.50
1.2
2.7
3.0
1.8
mmol/l
—
8
131
66
534
1.15
0.49
2.6
2.2
0.7
0.7
nmol/l
0.07
49
461
19
228
0.77
0.49
1.5
1.5
—
—
—
0
0
38
293
1.20
0.49
1.1
1.1
1.5
1.5
g/l
0.43
32
267
16
196
0.76
0.48
1.1
1.1
—
—
—
0
0
121
1019
1.10
0.48
1.9
1.8
—
—
—
0
0
24
278
0.80
0.47
1.0
1.0
—
—
—
0
0
37
286
1.20
0.47
1.5
1.5
—
—
—
0
0
67
545
1.14
0.47
3.2
2.7
362.4
389.3
ug/l
0.09
60
496
102
1043
0.90
0.44
3.2
4.2
4.5
14.3
ug/l
1.18
73
796
58
614
0.87
0.44
2.3
1.8
—
—
—
0
0
161
1381
1.09
0.44
1.2
1.2
39.0
38.7
au/ml
—
7
53
5
30
1.55
0.42
5.2
6.4
62.6
41.8
umol/l
—
5
24
15
105
1.33
0.41
1.5
2.6
0.6
2.3
u/field
—
7
66
0
14
0.00
0.41
0.0
1.0
—
—
—
0
0
8
55
1.35
0.40
1.3
1.4
9.7
9.2
ug/l
—
8
55
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
56
1.32
0.40
1.3
1.4
—
—
—
0
0
585
5602
0.96
0.39
2.2
2.3
—
—
—
0
0
64
528
1.13
0.38
5.5
6.1
23.2
23.9
mmol/l
0.96
59
484
1906
17453
1.03
0.38
4.2
3.5
1.4
1.5
mmol/l
0.65
1764
16427
10
66
1.41
0.38
1.8
1.4
—
—
—
0
0
10
66
1.41
0.38
1.8
1.4
—
—
—
0
0
45
478
0.87
0.38
1.5
2.3
137.7
134.5
g/l
0.51
38
385
18
132
1.27
0.37
1.1
1.1
—
—
—
0
0
93
786
1.10
0.37
1.4
1.4
—
—
—
0
0
42
446
0.87
0.36
3.4
4.3
1.2
1.4
mmol/l
1.10
42
437
11
75
1.36
0.36
1.3
1.7
—
—
—
0
0
1933
17715
1.03
0.36
4.4
3.8
2.8
2.8
mmol/l
0.16
1788
16604
9
66
1.26
0.36
2.0
1.8
—
—
—
0
0
47
383
1.14
0.35
1.1
1.3
2.1
3.8
u/ml
0.92
15
142
62
515
1.12
0.34
1.1
1.1
5.3
4.1
u/ml
0.20
17
183
21
159
1.23
0.34
1.2
1.7
—
—
—
0
0
6
41
1.36
0.34
1.0
1.1
—
—
—
0
0
28
219
1.19
0.34
1.1
1.3
10.9
18.8
u/ml
0.31
23
171
6
42
1.32
0.33
1.0
1.0
0.0
3.2
u/ml
—
6
31
6
42
1.32
0.33
1.2
1.2
—
—
—
0
0
17
126
1.25
0.33
5.0
2.8
998.6
888.8
u/ml
0.16
17
126
1831
16784
1.03
0.32
3.8
3.3
1.2
1.2
mmol/l
1.14
1689
15819
17
127
1.24
0.31
1.0
1.1
215.5
211.3
iu/ml
0.02
17
127
207
2018
0.95
0.31
2.4
2.3
2491.3
6860.6
u/l
2.36
62
649
172
1506
1.06
0.31
2.3
2.3
17.7
19.4
au/ml
0.09
13
106
7
49
1.32
0.31
1.1
1.4
—
—
—
0
0
14
103
1.26
0.29
1.4
1.7
—
719294.4
—
0
9
334
3209
0.96
0.28
1.9
2.0
—
—
—
0
0
85
851
0.92
0.28
1.3
1.4
—
—
—
0
0
12
87
1.28
0.28
3.3
1.9
—
—
—
0
0
12
87
1.28
0.28
3.2
1.9
—
—
—
0
0
12
87
1.28
0.28
3.2
1.9
—
—
—
0
0
12
87
1.28
0.28
3.2
1.9
—
—
—
0
0
8
60
1.24
0.27
1.9
3.1
—
—
—
0
0
8
62
1.20
0.26
2.6
2.3
—
—
—
0
0
38
313
1.13
0.26
1.6
1.2
—
—
—
0
0
153
1495
0.95
0.26
1.9
1.9
—
—
—
0
0
636
6029
0.97
0.26
2.3
2.5
—
—
—
0
0
26
277
0.87
0.25
1.5
3.5
25.5
83.0
mg/l
1.44
20
228
26
277
0.87
0.25
1.5
3.5
28.9
31.3
mg/l
0.13
20
229
11
128
0.80
0.25
1.2
1.0
—
—
—
0
0
15
114
1.22
0.25
1.2
1.2
—
34.4
—
0
8
18
140
1.19
0.24
1.4
1.4
303310.9
77184.8
e6/l
—
9
98
22
175
1.17
0.24
1.2
1.4
1.5
1.8
mmol/l
3.44
22
164
110
961
1.06
0.23
1.5
1.4
—
—
—
0
0
5
35
1.32
0.23
1.0
1.2
—
—
—
0
0
29
237
1.14
0.23
1.5
1.4
1.2
1.2
promille
0.08
23
187
11
126
0.81
0.23
1.5
1.5
0.9
1.0
g/l
1.02
11
126
86
850
0.94
0.22
1.3
1.4
—
—
—
0
0
86
849
0.94
0.22
1.3
1.4
—
—
—
0
0
68
586
1.08
0.21
3.2
2.4
203.2
685.0
e6/l
1.01
58
459
32
265
1.12
0.21
1.3
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
86
847
0.94
0.20
1.3
1.4
—
—
—
0
0
12
91
1.22
0.20
1.1
1.2
—
—
—
0
0
15
117
1.19
0.20
1.9
1.7
—
—
—
0
0
0
13
0.00
0.20
0.0
1.1
—
0.0
—
0
8
63
627
0.93
0.20
1.4
1.5
—
—
—
0
0
73
633
1.07
0.20
1.2
1.1
—
—
—
0
0
93
912
0.94
0.20
20.6
10.8
1.2
1.3
%
0.27
93
907
20
161
1.15
0.20
8.2
4.2
—
86.1
—
0
21
6
48
1.16
0.19
10.3
10.3
—
—
—
0
0
44
443
0.92
0.19
3.3
3.4
19.0
3093.8
u/ml
0.76
38
379
10
75
1.24
0.18
1.3
1.7
—
—
—
0
0
256
2444
0.97
0.18
2.2
2.5
2.4
2.4
mmol/l
0.08
217
2144
27
224
1.12
0.18
1.3
1.5
—
—
—
0
0
14
152
0.85
0.18
2.8
4.2
86.4
216.0
umol/l
—
9
94
30
251
1.11
0.18
1.2
1.1
92.9
95.4
%
0.26
30
233
70
689
0.94
0.17
2.3
1.9
—
—
—
0
0
214
1921
1.03
0.17
1.4
1.3
—
—
—
0
0
27
225
1.11
0.17
1.9
2.5
—
—
—
0
0
369
3498
0.97
0.17
1.6
1.5
—
—
—
0
0
20
209
0.89
0.16
8.3
3.7
6.5
6.4
mmol/l
0.05
14
180
254
2290
1.03
0.16
3.6
3.5
21.4
21.3
%
0.03
85
922
42
360
1.08
0.16
1.1
2.0
10.4
10.3
g/l
0.10
30
323
22
228
0.89
0.16
1.0
1.1
—
—
—
0
0
56
553
0.94
0.16
2.1
1.9
5.4
4.8
iu/l
0.22
21
202
67
586
1.06
0.16
3.2
2.4
3.7
15.7
e6/l
2.68
55
444
16
129
1.15
0.16
1.0
1.1
—
—
—
0
0
23
191
1.12
0.15
1.1
1.1
—
—
—
0
0
6
74
0.75
0.15
1.2
1.4
—
—
—
0
0
25
209
1.11
0.15
1.1
1.2
—
—
—
0
0
21
174
1.12
0.15
1.4
2.0
—
—
—
0
0
73
642
1.06
0.15
1.3
1.1
—
—
—
0
0
38
326
1.08
0.15
1.3
1.2
—
—
—
0
0
7
84
0.77
0.14
1.4
1.0
—
—
—
0
0
25
210
1.10
0.14
1.1
1.2
—
—
—
0
0
25
210
1.10
0.14
1.0
1.2
—
—
—
0
0
25
210
1.10
0.14
1.0
1.2
—
—
—
0
0
12
129
0.86
0.14
2.0
1.5
—
—
—
0
0
34
291
1.08
0.14
1.5
1.4
6.1
7.0
mmol/l
1.34
25
200
148
1328
1.03
0.13
12.8
14.3
1.2
1.2
inr
0.11
26
215
25
211
1.10
0.13
1.1
1.2
—
—
—
0
0
46
400
1.07
0.13
1.5
1.6
—
1554.3
—
0
7
11
87
1.17
0.13
6.5
3.2
—
—
—
0
0
193
1742
1.03
0.13
2.6
2.3
31.1
64.9
u/l
0.66
166
1482
13
105
1.15
0.12
1.9
1.5
8.9
3.3
u/l
—
8
50
45
393
1.06
0.12
1.2
2.0
3.9
3.8
g/l
0.21
27
305
45
393
1.06
0.12
1.2
2.0
7.1
7.3
g/l
0.34
30
326
45
393
1.06
0.12
1.2
2.0
—
—
—
0
0
28
240
1.08
0.11
3.0
3.5
33.5
134.1
u/ml
—
9
66
13
136
0.89
0.11
1.2
1.1
—
—
—
0
0
10
107
0.87
0.11
1.1
1.1
—
—
—
0
0
36
315
1.06
0.09
1.1
2.0
38.4
38.5
g/l
0.01
27
287
23
198
1.08
0.08
1.2
1.5
10.3
10.8
umol/l
0.15
23
190
188
1709
1.02
0.08
2.8
2.6
0.6
0.7
ug/l
0.56
95
991
6
54
1.03
0.08
1.0
1.1
—
—
—
0
0
43
380
1.05
0.08
1.2
2.0
3.0
3.1
g/l
0.25
28
314
16
136
1.09
0.07
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
18
180
0.93
0.07
1.1
1.1
—
—
—
0
0
7
76
0.85
0.07
1.0
1.2
—
61.8
—
0
11
98
886
1.03
0.07
1.7
1.6
—
—
—
0
0
9
96
0.87
0.06
1.1
1.1
—
—
—
0
0
26
228
1.06
0.06
1.9
1.8
—
—
—
0
0
12
101
1.10
0.06
1.7
2.3
15.1
16.7
umol/l
0.22
12
101
12
101
1.10
0.06
1.0
1.1
0.0
2.4
u/ml
—
6
55
96
909
0.98
0.06
20.2
10.9
0.8
0.7
%
1.10
96
904
96
909
0.98
0.06
20.2
11.0
95.6
94.3
%
1.55
96
904
36
346
0.96
0.04
1.1
2.1
0.2
0.6
g/l
1.64
29
322
19
168
1.05
0.03
1.1
1.1
—
—
—
0
0
27
242
1.03
0.02
1.6
1.4
—
—
—
0
0
20
193
0.96
0.02
1.2
1.2
—
—
—
0
0
413
3812
1.00
0.02
4.4
4.1
11.8
14.0
mg/mmol
0.17
248
2573
12
105
1.06
0.01
2.9
5.5
—
151.2
—
0
25
69
647
0.99
0.01
3.2
2.2
309.7
446.7
mg/l
6.53
69
618
35
318
1.02
0.01
1.1
1.1
—
—
—
0
0
84
772
1.01
0.01
1.6
1.6
0.1
0.1
iu/ml
0.02
19
161
17
152
1.04
0.00
1.0
1.1
—
—
—
0
0
12
106
1.05
0.00
3.8
4.0
—
—
—
0
0
21
194
1.00
0.00
1.1
1.2
—
—
—
0
0
104
965
1.00
0.00
1.5
1.7
4.1
4.3
mg/l
0.07
71
652
11
100
1.02
0.00
1.0
1.1
44.7
5.0
u/ml
—
6
53
11
100
1.02
0.00
1.1
1.1
—
—
—
0
0
11
100
1.02
0.00
1.1
1.1
—
—
—
0
0
11
101
1.01
0.00
1.1
1.1
—
—
—
0
0
11
106
0.96
0.00
1.1
1.1
—
—
—
0
0
11
106
0.96
0.00
1.2
2.5
50.1
68.9
nmol/l
1.82
11
101
27
248
1.01
0.00
1.6
1.3
356.0
218.9
titre
—
5
57
38
356
0.99
0.00
2.0
2.8
18.5
17.4
%
1.14
17
202
92
852
1.00
0.00
1.4
1.4
—
—
—
0
0
33
304
1.01
0.00
1.4
1.3
—
—
—
0
0
57
530
1.00
0.00
1.5
1.5
—
—
—
0
0
17
157
1.00
0.00
2.6
1.7
—
—
—
0
0
17
157
1.00
0.00
2.6
1.7
—
—
—
0
0
17
157
1.00
0.00
2.6
1.7
—
—
—
0
0
49
458
0.99
0.00
2.5
2.0
4.3
2.3
ug/l
0.44
44
415
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
7
72
0.90
0.00
1.9
2.0
—
—
—
0
0
7
69
0.94
0.00
1.6
1.1
—
—
—
0
0
8
82
0.90
0.00
1.0
1.2
—
19.0
—
0
18
7
67
0.97
0.00
1.9
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
27.0
—
0
6
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
7
67
0.97
0.00
1.9
2.0
—
—
—
0
0
8
75
0.99
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
5
49
0.95
0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
6
64
0.87
0.00
1.0
1.0
21.7
46.3
ng/l
—
6
42
0
5
0.00
0.00
0.0
1.2
—
92.2
—
0
5
8
75
0.99
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.87
0.00
1.2
3.4
—
96.2
—
0
19
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.88
0.00
1.0
1.0
239.5
300.6
ng/l
—
6
45
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
56
0.99
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_CROSSBITE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_CROSSBITE | 0.68 [0.47, 0.99] | 0.043 |
| Birth year | 0.992 [0.98, 1.0] | 0.067 |
During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 46029 females with K11_CROSSBITE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_CROSSBITE | 0.639 [0.41, 0.99] | 0.046 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 42490 males with K11_CROSSBITE died.
Mortality risk
Mortality risk for people of age
years, who have K11_CROSSBITE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.064% | 0.144% |
| 5 | 0.355% | 0.823% |
| 10 | 0.863% | 2.111% |
| 15 | 1.726% | 3.989% |
| 20 | 2.946% | 6.681% |
Relationships between endpoints
↥Index endpoint: K11_CROSSBITE – Crossbite
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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