Crossbite

K11_CROSSBITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.25
  • Hospital discharge: ICD-10 K07.25
  • Cause of death: ICD-10 K07.25

3 out of 7 registries used, show all original rules.

3183

4. Check minimum number of events

None

3183

5. Include endpoints

None

3183

6. Filter based on genotype QC (FinnGen only)

2986

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 107102 55446 51543
Only index persons 80238 41490 38748
Unadjusted period prevalence (%)
Whole population 1.52 1.59 1.44
Only index persons 1.50 1.53 1.48
Median age at first event (years)
Whole population 9.39 9.33 9.41
Only index persons 10.97 11.00 10.94

-FinnGen-

Key figures

All Female Male
Number of individuals 2986 1878 1108
Unadjusted period prevalence (%) 0.61 0.67 0.51
Median age at first event (years) 23.72 23.84 23.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3107
Matched controls
28712
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SAA04
NOMESCO Finland
Special examination of mouth
5.3
321.8
806
1767
EEC05
NOMESCO Finland
Le Fort I osteotomy
73.9
313.3
181
24
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
6.0
307.7
899
1833
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
+∞
307.7
3107
*
SBB10
NOMESCO Finland
Dental impressions
6.8
307.7
1555
3687
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
59.0
307.7
274
47
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
5.6
307.7
882
1912
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
6.3
307.7
887
1708
SJC10
NOMESCO Finland
Orthodontic band in one tooth
6.3
307.7
729
1336
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
5.5
307.7
819
1758
K07.24
ICD-10 Finland
Open bite
11.5
307.7
373
338
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
6.3
307.7
748
1383
EB1MA
NOMESCO Finland
Cephalometry with X-ray
5.9
307.7
822
1656
K07.14
ICD-10 Finland
Retrognaty, maxillary
47.6
307.7
307
66
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
5.3
302.1
754
1641
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
5.6
289.7
663
1333
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.1
281.6
726
1618
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
7.1
257.3
434
642
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
4.3
240.5
772
2031
SXC05
NOMESCO Finland
Other oral or dental procedure
3.9
239.8
934
2828
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
3.8
221.7
913
2854
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.4
219.7
669
1682
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.7
211.2
570
1300
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
197.5
1977
10332
SAA03
NOMESCO Finland
Extended examination of mouth
3.3
197.2
2225
12444
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.6
183.0
762
2368
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
5.0
182.3
445
928
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
4.8
179.9
462
1005
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.7
158.9
594
1705
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.7
157.5
590
1695
K07.10
ICD-10 Finland
Asymmetry of jaw
24.7
154.7
116
45
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
142.1
1676
8972
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
18.1
137.3
117
62
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
23.7
134.1
102
41
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.2
133.7
405
994
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.2
123.2
608
2057
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
14.4
118.3
113
75
K07.60
ICD-10 Finland
Snapping jaw
3.8
104.2
348
911
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.7
102.0
357
965
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
3.3
99.1
430
1336
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
28.0
99.0
71
24
SAA02
NOMESCO Finland
Basic examination of mouth
3.3
96.9
2790
20798
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.0
94.9
481
1636
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.2
91.8
423
1360
WZA90
NOMESCO Finland
Other medical or dental certificate
2.2
91.3
1144
5969
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.3
80.0
219
493
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
17.3
78.5
68
37
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.7
74.1
453
1692
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
11.9
73.4
78
62
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.9
72.7
392
1370
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
43.1
72.0
46
10
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
6.4
71.5
125
188
SAA01
NOMESCO Finland
Simple examination of mouth
2.4
71.3
2606
19610
EBB10
NOMESCO Finland
Insertion of dental implant
8.8
70.2
92
99
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
28.1
67.0
48
16
K00.00
ICD-10 Finland
Hypodontia
4.2
66.5
189
437
EB1WA, ,
NOMESCO Finland
11.8
66.4
71
57
SDA03
NOMESCO Finland
Periodontal treatment
1.9
61.1
1270
7685
K03.64
ICD-10 Finland
Dental calculus supragingival
1.9
59.9
1421
8951
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
14.1
59.3
57
38
K03.66
ICD-10 Finland
Tooth plaque
2.4
59.3
493
2118
K07.13
ICD-10 Finland
Retrognaty, mandibular
3.7
57.0
191
497
K02.0
ICD-10 Finland
Caries limited to enamel
1.9
55.5
1103
6530
Z01.2
ICD-10 Finland
Dental examination
1.8
55.2
1900
13285
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.8
54.0
1297
8123
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
4.0
53.7
161
387
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
11.4
51.6
56
46
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
16.9
51.3
45
25
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
5.2
50.8
108
196
EBB15
NOMESCO Finland
Insertion of dental implant abutment
10.1
49.1
58
54
K05.30
ICD-10 Finland
Periodontitis complex
2.5
48.5
355
1433
EB1TW
NOMESCO Finland
3D modelling of dentition
17.4
47.5
41
22
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
10.2
45.1
53
49
EBA00
NOMESCO Finland
Extraction of tooth
1.7
44.0
1412
9438
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
6.0
43.7
80
126
OIKK, ,
NOMESCO Finland
2.1
43.4
471
2238
EEC02
NOMESCO Finland
Rapid expansion of maxilla
410.4
43.0
44
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
41.7
309
1252
SFA10
NOMESCO Finland
One-surface restoration
1.7
41.7
1953
14344
SCA01
NOMESCO Finland
Preventive oral health care, short
1.7
40.6
1796
12949
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
4.3
40.6
109
241
D82
ICPC
Teeth/gum disease
1.7
40.5
1384
9336
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
4.0
40.2
120
287
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
3.3
39.9
158
458
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
39.0
1516
10537
K07.61
ICD-10 Finland
Cracking jaw joint
3.5
38.6
141
388
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
38.6
1636
11608
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
38.4
2372
18547
SJE90
NOMESCO Finland
Orthodontic finishing
5.3
37.5
78
139
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.1
37.4
412
1963
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.7
37.3
836
5013
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.5
36.7
62
90
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
6.9
36.4
58
79
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.1
35.6
364
1684
EB1S1
NOMESCO Finland
Photography of teeth
5.9
35.4
66
106
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
35.2
510
2673
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.8
34.7
600
3325
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
34.7
678
3898
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.2
33.9
94
213
SPC20
NOMESCO Finland
Implant borne crown
8.3
33.0
45
51
K07.4
ICD-10 Finland
Malocclusion, unspecified
3.5
32.8
117
317
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
10.5
32.2
37
33
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
32.1
792
4843
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
2.6
32.0
200
746
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.7
31.8
717
4277
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
8.9
31.1
40
42
K03.00
ICD-10 Finland
Approximal wear
2.2
30.6
271
1182
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
11.9
30.3
32
25
K02.1
ICD-10 Finland
Caries of dentine
1.6
29.9
2025
15610
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
29.8
936
6063
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
29.7
547
3074
OIKH, ,
NOMESCO Finland
2.1
29.7
329
1564
OIKVA, ,
NOMESCO Finland
2.3
27.8
220
914
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
27.7
1932
14853
D19
ICPC
Teeth/gum symptom/complaint
1.6
27.7
1019
6828
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.2
27.1
73
162
SXC03
NOMESCO Finland
Other oral or dental procedure
5.9
26.1
48
76
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.5
25.6
171
658
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
24.7
991
6730
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
7.1
24.6
38
50
H02AB09
ATC
hydrocortisone; systemic
2.7
24.5
134
467
127
Kela drug reimbursment
Transplant complication
3.7
24.5
78
196
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.5
24.2
1253
8962
G47.3
ICD-10 Finland
Sleep apnoea
1.7
24.2
463
2621
SPB20
NOMESCO Finland
Temporary bridge
9.7
23.9
29
28
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.7
23.3
76
194
SCA02
NOMESCO Finland
Preventive oral health care
1.6
23.3
797
5214
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
22.9
334
1741
K06.00
ICD-10 Finland
Local gingivore traction
3.5
22.8
80
215
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
22.1
156
616
OIKAL, ,
NOMESCO Finland
2.2
21.7
184
787
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
8.4
21.7
29
32
OIKJA, ,
NOMESCO Finland
3.3
21.6
82
232
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.6
21.3
532
3224
OIKRE, ,
NOMESCO Finland
3.2
21.2
87
258
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
3.7
21.1
67
168
602
Kela drug reimbursment
Children's severe malnutrition
3.2
20.4
81
236
SFA20
NOMESCO Finland
Two-surface restoration
1.4
20.2
1710
13258
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
20.2
575
3593
OIKIN, ,
NOMESCO Finland
3.7
20.0
65
166
-1, ,
NOMESCO Finland
1.4
19.7
1441
10864
ZXA10
NOMESCO Finland
Bilateral
1.7
19.5
448
2653
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
19.4
294
1547
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
4.2
19.4
52
115
SPC10
NOMESCO Finland
Standard dental crown
4.2
19.0
52
117
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
3.0
18.9
85
267
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
18.1
579
3706
K07.23
ICD-10 Finland
Deep bite
1.8
18.0
315
1730
Z3231
NOMESCO Finland
Registered nurse
1.5
18.0
826
5693
SPAT1385
SPAT
Extensive health check-up on fifth grade
1.8
17.8
313
1723
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.8
17.7
89
297
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
17.7
493
3056
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.4
17.5
120
468
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
3.7
17.5
57
146
SAALT, ,
NOMESCO Finland
2.3
17.2
130
529
K05.31
ICD-10 Finland
Periodontitis pronounced
2.0
17.2
201
972
EMAK, ,
NOMESCO Finland
2.4
16.8
116
454
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
16.8
135
565
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
4.0
16.8
49
116
L04AD02
ATC
tacrolimus; systemic
3.5
16.7
57
151
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
15.7
16.6
27
16
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
5.5
16.4
32
54
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
5.7
16.3
31
51
SFA00
NOMESCO Finland
Small restoration
1.6
16.3
390
2329
Z13.88
ICD-10 Finland
Special screening examination for other specified diseases and disorders
1.8
15.8
249
1326
K07.33
ICD-10 Finland
Crowding of tooth or teeth
4.4
15.8
40
85
ECA00
NOMESCO Finland
Surgical exposure of tooth
3.3
15.7
59
166
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
4.5
15.6
38
78
K06.18
ICD-10 Finland
Another gingival hyperplasia
4.9
15.6
35
67
R06.5
ICD-10 Finland
Mouth breathing
1.8
15.2
251
1355
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.9
14.9
71
231
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
14.3
120
512
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.3
14.1
111
461
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
4.4
13.9
35
74
K07.32
ICD-10 Finland
Displacement of tooth or teeth
4.4
13.9
35
74
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
3.7
13.9
45
115
Z94.0
ICD-10 Finland
Kidney transplant status
3.4
13.6
48
130
FM2CE, ,
NOMESCO Finland
2.2
13.6
115
492
K01.0
ICD-10 Finland
Embedded teeth
2.2
13.5
115
493
SFA30
NOMESCO Finland
Three-surface restoration
1.4
13.5
933
6845
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.3
13.4
104
429
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.7
13.3
266
1514
Z2445
NOMESCO Finland
Psychologist
1.7
13.2
247
1380
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.7
13.2
257
1453
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
13.2
406
2565
L17
ICPC
Foot/toe symptom/complaint
1.4
13.2
849
6158
H01
ICPC
Ear pain/earache
1.5
13.1
539
3610
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
2.5
13.0
80
297
EB4VA, ,
NOMESCO Finland
1.6
12.9
313
1871
SPAT1384
SPAT
Extensive health check-up on first grade
1.7
12.8
245
1377
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
12.8
904
6645
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.0
12.8
141
668
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
1.8
12.7
179
920
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
11.9
12.7
23
18
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
12.7
536
3606
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
4.7
12.6
29
57
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
12.6
152
744
SAE02, ,
NOMESCO Finland
3.4
12.5
46
128
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
12.5
246
1394
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
26.3
12.4
17
6
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
12.4
199
1065
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
12.3
193
1026
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.9
12.3
153
757
Q35.1
ICD-10 Finland
Cleft hard palate
9.3
12.3
25
25
UDC00
NOMESCO Finland
Ear microscopy
1.7
12.2
227
1266
SPE02
NOMESCO Finland
Metal-framed partial denture
4.1
12.2
34
78
K10.00
ICD-10 Finland
Torus mandibularis
4.7
12.2
28
55
OIKKK, ,
NOMESCO Finland
3.4
12.1
43
117
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
13.0
12.1
21
15
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
12.1
1814
14816
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
12.0
1689
13670
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
12.0
620
4325
XF602
NOMESCO Finland
Bloodpressure monitoring
3.2
11.8
47
138
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
5.5
11.7
23
39
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.4
11.7
77
296
WX402
NOMESCO Finland
General anaesthesia
1.4
11.6
564
3892
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
5.9
11.6
21
33
J34.2
ICD-10 Finland
Deviated nasal septum
2.0
11.5
122
570
ECB17
NOMESCO Finland
Operation of gingival cleft
19.7
11.5
17
8
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
3.2
11.5
45
131
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
11.4
399
2585
K07.28
ICD-10 Finland
Another anomaly in the relationship between the dental arches
10.2
11.4
22
20
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.0
11.4
118
548
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
2.7
11.3
59
202
OAA40, ,
SPAT
1.6
11.2
274
1639
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
3.8
11.2
34
83
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.0
11.2
48
147
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
11.2
252
1479
H01AC01
ATC
somatropin; parenteral
2.6
11.1
63
225
SPAT1301
SPAT
No procedures
1.3
11.1
855
6345
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
21.2
11.1
16
7
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
111.3
11.1
12
*
Z2446
NOMESCO Finland
Social worker
1.6
10.9
291
1778
K06.01
ICD-10 Finland
General gingival retraction
4.7
10.9
25
49
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
10.8
533
3681
F45.8
ICD-10 Finland
Other somatoform disorders
1.7
10.8
218
1244
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.8
10.8
179
968
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
4.0
10.8
30
69
KMAK, ,
NOMESCO Finland
1.3
10.7
1069
8217
R51.80
ICD-10 Finland
Headache
1.4
10.7
508
3483
EBA10
NOMESCO Finland
Operative extraction of tooth
1.4
10.7
524
3615
WX290
NOMESCO Finland
Other blockage of nerve
1.3
10.6
1528
12324
K03.11
ICD-10 Finland
Abrasion dentifrice of teeth
2.5
10.6
68
259
SPAT1312
SPAT
General health counselling
1.3
10.4
1143
8894
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
10.4
525
3641
SPC01
NOMESCO Finland
Fixed dental crown
3.3
10.3
39
111
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
10.3
764
5628
BE00A, ,
NOMESCO Finland
11.0
10.3
19
16
L04AX01
ATC
azathioprine; systemic
1.9
10.3
121
588
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
2.0
10.3
114
543
Z3226
NOMESCO Finland
Physiotherapist
1.4
10.2
488
3349
K03.09
ICD-10 Finland
Abrasion of the teeth UNS
3.3
10.1
37
103
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.4
10.1
641
4608
EEC99
NOMESCO Finland
Other reconstructive operations on maxilla
102.0
10.1
11
*
EB1VA, ,
NOMESCO Finland
1.5
10.0
297
1859
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.0
9.9
28
65
RK220, ,
NOMESCO Finland
4.1
9.9
27
61
G50.1
ICD-10 Finland
Atypical facial pain
3.1
9.8
41
124
OIKSI, ,
NOMESCO Finland
4.6
9.8
23
46
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.5
9.8
279
1730
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
9.8
988
7589
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.5
9.7
58
213
V03AG01
ATC
sodium cellulose phosphate; systemic
3.9
9.7
28
66
SPAT1310
SPAT
Counselling related to known health issue
1.3
9.7
946
7233
Z29.8
ICD-10 Finland
Other specified prophylactic measures
1.8
9.6
138
715
K03.28
ICD-10 Finland
Other erosion of teeth
2.3
9.6
74
306
RETH, ,
NOMESCO Finland
5.2
9.6
20
36
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
51.0
9.3
11
*
WYA10
NOMESCO Finland
Emergency care or similar visit
1.6
9.3
236
1426
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
3.3
9.3
34
95
Z2221
NOMESCO Finland
Medical doctor
1.3
9.3
651
4747
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
3.4
9.2
33
91
XA800
NOMESCO Finland
Neuropsychological investigation
1.7
9.2
162
893
Z94.4
ICD-10 Finland
Liver transplant status
4.5
9.1
22
45
A11CC03
ATC
alfacalcidol; systemic
2.5
9.1
56
209
R4110
NOMESCO Finland
Physiotherapy
1.3
9.1
619
4490
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
3.4
9.1
32
87
K05.1
ICD-10 Finland
Chronic gingivitis
1.6
9.0
210
1243
K02.3
ICD-10 Finland
Arrested dental caries
2.2
9.0
74
315
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
9.0
280
1770
SDA05
NOMESCO Finland
Very demanding periodontal treatment
1.6
8.9
195
1136
B07.9
ICD-10 Finland
Verruca simplex
1.8
8.9
129
671
R4190
NOMESCO Finland
Nutritional therapy
1.6
8.9
195
1137
A98
ICPC
Health maint/preventive medicine
2.7
8.9
3071
27822
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
9.9
8.8
17
16
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.4
8.8
390
2640
WX882
NOMESCO Finland
High dependency care
1.8
8.8
135
716
OIKQH, ,
NOMESCO Finland
12.7
8.7
15
11
VALMI, ,
NOMESCO Finland
1.3
8.7
1078
8465
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
3.5
8.6
29
77
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.1
8.5
81
365
RK110, ,
NOMESCO Finland
3.6
8.5
28
73
K08.80
ICD-10 Finland
Toothache NOS
1.5
8.5
242
1502
SBA00
NOMESCO Finland
Microbiological examinations
2.2
8.4
72
312
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
8.4
428
2966
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
46.3
8.4
10
*
K01.14
ICD-10 Finland
Retained premolar with obstruction in the upper jaw
7.4
8.3
19
24
SGC00
NOMESCO Finland
Medication, disinfection of root canals
1.5
8.3
252
1584
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.3
929
7199
XX7LW, ,
NOMESCO Finland
13.0
8.3
14
10
SCE00
NOMESCO Finland
Fissure sealant
1.4
8.2
348
2333
OAA32, ,
SPAT
1.9
8.2
107
539
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
8.2
146
807
SPAT1263
SPAT
Sampling
1.3
8.2
1158
9222
SPA05
NOMESCO Finland
Surgical guide
15.1
8.2
13
8
4361
FHL
Lip plastic or reconstruction due to cleft lip
25.5
8.1
11
*
N03AX16
ATC
[U] pregabalin
1.4
8.1
383
2619
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.1
602
4417
SAE01, ,
NOMESCO Finland
2.8
8.1
40
134
L04AA01
ATC
[U] ciclosporin
3.1
8.0
33
100
K02.2
ICD-10 Finland
Caries of cementum
2.1
7.9
72
320
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
7.9
203
1232
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
7.3
7.9
18
23
5AB14, ,
NOMESCO Finland
4.3
7.8
20
43
KAC00
NOMESCO Finland
Nephrectomy
4.2
7.8
21
47
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.5
7.8
275
1781
SXC05, ,
SPAT
8.7
7.8
16
17
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.6
7.8
205
1249
L04AD01
ATC
ciclosporin; systemic
2.3
7.8
58
237
SPAT1260
SPAT
Consultation of another employee
1.4
7.7
423
2964
OAA50, ,
SPAT
1.8
7.7
107
551
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
7.7
454
3221
UDM02
NOMESCO Finland
Sinoscopy
2.5
7.6
48
182
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
2.8
7.6
36
118
101
Kela drug reimbursment
Anterior pituitary hypofunction
2.5
7.6
45
166
SPAT1058
SPAT
PEF monitoring instruction
1.6
7.5
183
1095
E0000UV, ,
ATC
1.2
7.5
1195
9614
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
7.5
142
799
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.5
978
7698
K03.29
ICD-10 Finland
Erosion of teeth occupational
2.4
7.5
48
184
4364
FHL
Pharyngeal tongue plastic
41.7
7.4
9
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
1.9
7.4
87
424
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
3.2
7.4
29
85
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.8
7.4
36
120
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
8.7
7.4
15
16
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.0
7.3
72
330
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
7.3
206
1276
H13
ICPC
Plugged feeling ear
1.4
7.3
355
2440
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
23.2
7.3
10
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.6
7.3
166
980
DHB50
NOMESCO Finland
Turbinoplasty
2.1
7.2
67
300
SFB40
NOMESCO Finland
Filling of four surfaces reproduced outside mouth
4.4
7.2
18
38
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
74.2
7.2
8
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.9
7.1
91
456
DFF00
NOMESCO Finland
Pure tone audiometry
1.6
7.1
172
1030
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
2.7
7.1
37
128
RD210, ,
NOMESCO Finland
1.8
7.1
106
559
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.1
488
3539
RS311, ,
NOMESCO Finland
4.5
7.0
17
35
WKPAL, ,
NOMESCO Finland
1.9
7.0
81
393
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
6.6
7.0
17
24
Z94.1
ICD-10 Finland
Heart transplant status
4.3
7.0
18
39
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.5
6.9
221
1404
IEP02
NOMESCO Finland
Child-centred family therapy
2.3
6.9
51
208
K03.18
ICD-10 Finland
Other abrasion of the teeth
2.4
6.9
44
168
E34.35
ICD-10 Finland
Abnormal growth retardation
2.2
6.9
56
238
XCW10
NOMESCO Finland
Assessment of vision
3.8
6.9
21
52
EAB30
NOMESCO Finland
Correction of cleft lip
8.7
6.9
14
15
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
27.8
6.9
9
*
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
5.5
6.9
19
32
SGA05
NOMESCO Finland
Opening and preparing the root canals, extremely complicated And time consuming
1.6
6.9
148
862
ECA50
NOMESCO Finland
Periodontal flap surgery
3.5
6.8
23
61
J01CA04
ATC
amoxicillin; systemic
1.3
6.8
2630
23186
WX400
NOMESCO Finland
Inhalation anesthesy
1.6
6.8
146
850
ZX199
NOMESCO Finland
Other rote
3.4
6.8
24
66
Z31.5
ICD-10 Finland
Genetic counselling
1.6
6.7
167
1005
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
6.7
6.7
16
22
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.7
424
3034
HAMTE, ,
NOMESCO Finland
3.3
6.7
25
71
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
3.3
6.7
25
71
L04AA06
ATC
mycophenolic acid; systemic
2.2
6.7
52
217
Z00.1
ICD-10 Finland
Routine child health examination
1.3
6.7
758
5855
WX725
NOMESCO Finland
Noninvasive ventilation
1.7
6.7
110
596
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.4
6.7
45
177
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.3
6.6
410
2925
SPAT1153
SPAT
Removal of sutures
1.3
6.6
549
4080
H92.0
ICD-10 Finland
Otalgia
1.5
6.6
211
1342
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
6.6
159
951
H02AB04
ATC
methylprednisolone; systemic
1.5
6.6
239
1558
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
6.6
846
6632
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
37.0
6.5
8
*
G44.2
ICD-10 Finland
Tension-type headache
1.4
6.5
325
2243
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
6.5
104
560
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
2.6
6.5
36
129
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
1.7
6.5
118
659
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
15.4
6.4
10
6
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
3.2
6.4
25
73
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
5.4
6.4
18
31
ZX121
NOMESCO Finland
Central venous catheter
3.0
6.4
28
88
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
1.9
6.3
82
414
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
3.6
6.3
20
51
M79.1
ICD-10 Finland
Myalgia
1.4
6.3
338
2359
K07.68
ICD-10 Finland
Other disorders of the jaw joint
2.9
6.3
29
94
ECA30
NOMESCO Finland
Excision of lesion of gingiva
2.9
6.3
29
94
XFE00
NOMESCO Finland
Epicardial ultrasonography
2.6
6.3
36
131
P24
ICPC
Specific learning problem
1.9
6.3
75
369
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.2
6.3
1293
10628
XX4AW, ,
NOMESCO Finland
2.4
6.3
41
159
K05.38
ICD-10 Finland
Other chronic periodontitis
2.3
6.3
46
188
H66
ICD-10 Finland
Suppurative and unspecified otitis media
1.6
6.2
144
854
M79.6
ICD-10 Finland
Pain in limb
1.2
6.2
932
7418
Z29.9
ICD-10 Finland
Prophylactic measure, unspecified
3.0
6.2
26
80
DFF20
NOMESCO Finland
Audiometry for children
2.5
6.1
37
138
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.1
673
5174
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
2.0
6.1
59
269
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
6.1
221
1441
SPAT1044
SPAT
Tympanometry
1.8
6.1
83
426
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.7
6.1
112
627
RK230, ,
NOMESCO Finland
3.7
6.1
19
48
OIKRM, ,
NOMESCO Finland
+∞
6.1
6
*
SJC04, ,
NOMESCO Finland
2.7
6.0
31
107

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
130
455
2.71
23.59
3.2
3.1
30.83
21.66
mu/l
0.65
123
423
647
4328
1.48
16.19
3.4
3.0
—
—
—
0
0
355
2133
1.61
14.37
6.1
4.5
1.52
1.58
%
0.52
319
1966
481
3111
1.51
14.02
13.3
7.5
1.20
1.17
mmol/l
1.31
451
2949
1251
9586
1.34
13.74
11.2
7.4
1.22
1.22
mmol/l
1.98
1090
8423
1169
8867
1.35
13.74
3.6
2.5
74.80
71.59
nmol/l
3.16
1075
8247
110
461
2.25
13.68
1.8
1.7
—
—
—
0
0
38
87
4.07
13.65
9.7
8.1
1.95
2.77
mg/l
1.68
30
72
240
1321
1.74
13.57
2.0
1.9
7.32
7.23
u/l
0.05
182
995
1919
15689
1.34
13.41
5.0
3.9
8.94
9.09
mm/h
0.23
1785
14587
52
161
3.02
11.94
41.3
29.9
137.30
135.12
ug/l
0.06
47
144
2138
17929
1.33
11.49
4.3
3.7
14.42
14.47
pmol/l
0.41
1923
16313
198
1083
1.74
11.46
23.1
12.2
1.15
1.14
mg/l
0.04
190
1045
409
2664
1.48
11.39
11.6
6.3
1.57
1.54
mmol/l
0.09
367
2149
2417
20652
1.37
11.38
4.9
4.3
1.89
2.07
mu/l
0.91
2231
19366
410
2680
1.48
11.20
11.5
6.2
5.85
5.86
kpa
0.14
405
2598
365
2343
1.50
10.90
3.0
2.3
333.02
363.92
nmol/l
2.59
334
2201
374
2418
1.49
10.78
12.1
6.0
4.97
4.92
kpa
0.18
368
2349
297
1833
1.55
10.65
10.8
6.5
—
—
—
0
0
244
1448
1.60
10.35
9.6
5.2
68.43
68.24
ng/l
0.02
224
1350
1544
12499
1.28
10.25
10.0
7.0
0.20
0.19
e9/l
0.37
1349
10996
249
1489
1.59
10.24
4.3
3.6
68.80
69.08
e9/l
0.03
188
1028
254
1545
1.57
9.71
1.9
1.7
17.32
18.52
iu/l
0.26
195
1208
36
102
3.29
9.61
3.9
3.8
—
—
—
0
0
270
1678
1.53
9.38
2.7
2.2
11.35
11.09
nmol/l
0.16
245
1528
1432
11565
1.27
9.36
9.6
6.9
8.37
8.22
%
1.10
1348
10931
1459
11821
1.27
9.24
9.0
6.5
52.67
53.78
%
2.95
1377
11211
1478
12008
1.26
9.08
9.3
6.7
32.21
31.59
%
1.33
1398
11393
1530
12494
1.26
8.95
9.1
6.6
2.01
2.08
e9/l
2.06
1341
11093
1375
11099
1.26
8.85
9.7
6.8
0.66
0.66
%
0.13
1287
10470
1118
8808
1.27
8.82
12.0
7.3
1.22
1.22
mmol/l
1.00
1024
8202
340
2243
1.45
8.80
10.3
6.3
7.40
7.41
ph
0.58
11
169
1417
11486
1.26
8.77
9.4
6.7
3.09
2.93
%
1.46
1332
10853
1407
11407
1.26
8.65
9.7
7.0
—
—
—
0
0
340
2252
1.44
8.61
10.4
6.3
5.06
5.06
kpa
0.06
324
2164
1482
12114
1.25
8.38
9.3
6.6
0.04
0.04
e9/l
1.34
1276
10466
1352
10942
1.25
8.33
11.4
8.8
0.00
0.00
e9/l
0.94
1090
8811
1479
12099
1.25
8.25
9.3
6.6
0.54
0.55
e9/l
0.50
1276
10462
28
75
3.47
8.18
1.7
1.6
18.30
18.13
nmol/l
—
10
24
1788
14950
1.25
8.15
7.0
6.5
90.06
85.57
u/l
2.43
1661
14124
73
328
2.08
7.78
4.5
3.1
—
—
—
0
0
77
355
2.03
7.67
3.5
3.1
1.39
1.31
e9/l
0.29
65
293
392
2726
1.38
7.49
3.2
2.6
2.53
2.49
g/l
0.78
373
2547
34
109
2.90
7.46
1.1
1.1
—
—
—
0
0
252
1620
1.48
7.46
11.6
6.9
10.16
9.63
kpa
3.86
241
1562
34
110
2.88
7.35
1.0
1.0
—
—
—
0
0
346
2366
1.40
7.32
1.3
1.2
—
—
—
0
0
67
300
2.09
7.23
3.6
3.2
0.23
0.19
e9/l
0.93
54
240
1629
13581
1.23
7.22
11.4
8.9
3.64
3.81
e9/l
2.31
1400
11752
1731
14548
1.22
6.99
4.7
3.9
—
—
—
0
0
354
2449
1.38
6.98
14.3
8.9
—
—
—
0
0
458
3304
1.33
6.87
4.7
3.4
660.96
875.04
ng/l
0.89
367
2716
55
235
2.18
6.71
4.2
3.4
295.12
286.62
e6/l
0.06
41
157
954
7563
1.24
6.70
7.1
5.4
37.37
37.17
g/l
0.57
887
7117
41
154
2.48
6.68
2.1
1.8
—
—
—
0
0
99
521
1.78
6.67
4.0
6.2
1.76
1.58
%
0.70
93
484
57
248
2.14
6.65
4.8
3.0
1.68
1.73
umol/l
0.18
57
239
168
1018
1.56
6.59
7.5
3.9
21.97
22.02
s
0.05
150
911
66
305
2.02
6.58
3.7
3.2
539.40
542.69
e6/l
0.02
53
239
421
3037
1.33
6.30
3.2
2.6
14.34
14.27
umol/l
0.07
402
2868
494
3645
1.30
6.28
1.4
1.4
20.05
19.92
nmol/l
0.08
411
3214
336
2347
1.36
6.23
17.9
9.8
25.01
24.72
mmol/l
1.05
336
2340
362
2559
1.35
6.22
2.0
1.6
—
—
—
0
0
96
516
1.74
6.05
4.1
6.2
0.87
0.92
%
0.81
90
482
27
86
2.92
6.04
4.1
3.8
4.13
3.43
%
—
8
35
355
2515
1.34
6.01
3.4
2.7
23.12
23.57
%
0.27
317
2237
348
2459
1.35
5.99
1.9
1.9
—
—
—
0
0
305
2128
1.36
5.71
1.6
1.3
380.94
248.69
u/ml
0.60
285
1980
1350
11210
1.20
5.70
3.4
2.9
75.36
82.19
ug/l
0.80
1277
10562
128
755
1.59
5.68
2.5
1.7
—
—
—
0
0
281
1943
1.37
5.57
16.8
9.8
6.86
6.69
mmol/l
0.21
272
1889
272
1871
1.38
5.56
4.3
3.6
32.72
32.16
%
0.33
188
1386
123
726
1.59
5.46
2.6
1.8
99.18
97.80
u/ml
0.03
11
102
1397
11670
1.19
5.43
6.5
4.9
6.13
6.34
mmol/l
3.63
1282
10797
208
1375
1.43
5.37
1.5
1.4
—
—
—
0
0
165
1047
1.48
5.28
4.2
3.6
158.27
147.33
ng/l
0.10
146
926
684
5362
1.23
5.13
3.3
2.5
2.76
2.74
mg/l
0.09
603
4679
407
3014
1.29
5.00
12.2
5.7
0.82
0.82
mmol/l
0.05
383
2881
531
4068
1.25
4.91
3.9
2.8
589.98
569.53
mosm/kgh2o
1.02
466
3521
934
7578
1.20
4.90
1.5
1.5
2.26
2.03
u/ml
0.16
187
1783
2623
23318
1.25
4.87
12.9
10.5
20.64
21.47
mg/l
0.56
1932
17070
524
4023
1.24
4.75
3.7
2.8
2356.12
3871.18
umol/l
0.69
475
3645
97
565
1.61
4.60
1.4
1.5
0.26
0.29
nmol/l
0.22
70
455
508
3901
1.24
4.59
3.3
2.9
91.49
111.88
ug/g
1.15
395
3093
23
80
2.67
4.45
3.3
2.2
—
—
—
0
0
135
856
1.48
4.39
7.4
5.5
0.28
0.36
g/l
0.47
93
500
39
174
2.08
4.38
1.5
1.2
—
—
—
0
0
45
212
1.98
4.37
6.3
4.8
1.32
1.73
ug/l
0.83
45
205
613
4824
1.22
4.37
1.8
1.7
1.30
1.36
mmol/l
0.91
528
4223
557
4346
1.22
4.32
3.6
2.2
1.45
1.10
mg/l
0.58
391
3122
204
1398
1.37
4.32
1.3
1.2
—
—
—
0
0
808
6541
1.19
4.25
1.9
1.7
100.23
96.68
pmol/l
1.38
403
3505
2481
22006
1.21
4.22
14.7
11.3
139.65
139.63
mmol/l
0.10
2405
21368
213
1481
1.35
4.13
3.2
3.2
4.83
4.78
pmol/l
0.23
192
1347
856
6981
1.18
4.12
9.5
8.5
1.16
1.13
inr
0.52
252
2203
32
136
2.19
4.08
2.6
2.0
—
—
—
0
0
420
3202
1.25
4.04
1.5
1.5
120231647.90
27020634.62
pmol/l
0.99
346
2772
747
6038
1.19
3.97
3.0
2.4
—
—
—
0
0
386
2922
1.25
3.96
1.3
1.2
—
—
—
0
0
30
126
2.21
3.94
7.4
5.2
94.72
84.67
mg/l
0.32
25
113
739
5971
1.19
3.94
3.0
3.0
2.37
2.37
mmol/l
0.49
643
5417
2482
22055
1.20
3.92
14.7
11.3
3.92
3.92
mmol/l
0.11
2385
21349
768
6230
1.18
3.91
9.9
7.2
—
—
—
0
0
54
282
1.78
3.88
4.9
3.5
—
—
—
0
0
179
1224
1.37
3.87
1.2
1.2
3.11
3.54
u/ml
0.21
119
760
162
1091
1.39
3.84
1.1
1.1
1.25
1.40
u/ml
0.10
109
638
849
6954
1.18
3.84
4.4
3.5
30.62
31.10
u/l
0.18
821
6640
310
2296
1.28
3.82
1.6
1.5
—
—
—
0
0
821
6709
1.18
3.82
1.6
1.5
1.85
1.94
g/l
0.98
457
3895
1110
9314
1.16
3.64
3.0
2.6
—
—
—
0
0
700
5667
1.18
3.62
2.9
2.8
34.52
37.66
ng/l
0.15
380
2997
414
3192
1.23
3.59
1.6
1.4
427.43
539.01
titre
0.51
70
583
2698
24213
1.23
3.58
11.1
9.3
—
—
—
0
0
17
58
2.72
3.45
1.2
1.1
—
—
—
0
0
163
1123
1.36
3.40
1.1
1.1
7.28
7.01
u/ml
0.07
116
737
279
2073
1.27
3.37
4.6
3.3
0.22
0.22
g/l
0.07
260
1963
157
1077
1.37
3.37
1.2
1.1
1.59
3.43
u/ml
3.13
111
706
126
833
1.41
3.36
10.0
5.3
1.18
1.29
%
0.47
126
828
2931
26589
1.33
3.33
19.1
15.4
262.49
262.43
e9/l
0.02
2822
25756
714
5826
1.17
3.33
2.7
2.5
53.60
58.54
u/l
2.70
651
5413
31
142
2.03
3.32
2.0
2.3
3.93
3.97
mmol/l
0.32
31
142
1116
9417
1.15
3.32
7.4
5.9
11.45
11.69
umol/l
0.18
1040
8803
42
214
1.82
3.31
1.3
1.2
—
—
—
0
0
30
136
2.05
3.31
2.0
2.3
—
—
—
0
0
89
552
1.50
3.30
6.0
2.9
11.14
6.34
umol/l
1.01
74
440
2385
21218
1.17
3.24
16.4
13.1
15.74
13.96
%
0.47
2342
20784
2932
26610
1.32
3.22
19.0
15.3
88.41
88.83
fl
4.87
2878
26228
307
2322
1.25
3.20
1.7
1.6
1138.61
1161.92
nmol/l
0.18
230
1821
2932
26614
1.32
3.18
19.0
15.3
29.61
29.73
pg
3.26
2878
26233
49
266
1.71
3.15
3.4
2.8
818.43
682.61
e6/l
0.81
49
261
27
120
2.09
3.14
1.1
1.1
471.32
394.00
nmol/l
0.87
22
111
210
1520
1.30
3.14
4.8
3.7
—
—
—
0
0
2932
26619
1.32
3.13
19.1
15.3
4.60
4.59
e12/l
0.72
2813
25705
21
85
2.29
3.06
3.3
2.3
149.14
166.45
ug/g
0.27
21
78
2932
26628
1.31
3.04
19.1
15.3
6.69
6.69
e9/l
0.00
2818
25730
30
141
1.98
3.03
2.0
2.3
105.37
105.91
mmol/l
0.24
30
141
59
341
1.61
3.01
1.2
1.2
—
—
—
0
0
2932
26636
1.31
2.96
19.4
15.4
135.63
135.93
g/l
0.59
2875
26260
53
300
1.64
2.94
1.3
1.4
—
—
—
0
0
2926
26580
1.30
2.90
19.7
15.5
40.28
40.53
%
0.67
2749
25240
1590
13826
1.13
2.83
4.4
3.8
3705.55
541.41
e6/l
0.67
20
173
1028
8703
1.14
2.82
3.7
2.9
6.15
5.98
ph
1.14
98
869
115
776
1.38
2.78
2.5
2.2
—
—
—
0
0
10
26
3.56
2.74
1.6
3.3
—
—
—
0
0
82
525
1.46
2.67
1.6
1.7
—
3.38
—
0
8
59
353
1.56
2.64
1.1
1.1
3.24
8.00
iu/ml
—
9
73
68
420
1.51
2.64
1.6
1.5
15.01
17.06
u/l
0.30
58
364
1228
10546
1.13
2.63
3.8
3.2
0.00
0.00
estimate
0.14
203
1952
51
296
1.60
2.60
1.3
1.4
0.47
0.35
g/l
1.44
41
228
51
296
1.60
2.60
1.3
1.4
2.44
2.67
g/l
0.49
42
229
51
296
1.60
2.60
1.3
1.4
6.24
6.57
g/l
0.40
41
230
139
978
1.33
2.60
2.4
1.5
170.33
201.76
u/ml
0.84
72
502
619
5091
1.15
2.57
5.2
3.8
7.39
7.40
ph
0.55
102
956
306
2373
1.21
2.55
7.4
3.8
6.41
6.98
umol/l
0.33
271
2020
74
470
1.47
2.52
4.4
6.6
1.30
1.23
mmol/l
0.26
65
411
20
87
2.13
2.50
2.9
1.8
—
—
—
0
0
848
7138
1.13
2.50
2.0
1.9
—
—
—
0
0
1891
16685
1.12
2.48
4.9
4.3
37.36
37.99
mmol/mol
2.56
1745
15686
1217
10476
1.12
2.47
3.8
3.2
0.00
0.00
estimate
0.50
213
2048
15
58
2.40
2.44
2.9
2.4
24.56
32.25
umol/l
—
9
44
49
287
1.59
2.43
5.3
8.9
10.40
11.52
mmol/l
2.47
43
258
262
2012
1.22
2.42
3.4
3.0
9.82
10.16
g/l
0.87
247
1881
49
288
1.58
2.40
5.3
8.9
105.14
105.56
mmol/l
0.19
43
259
55
333
1.54
2.37
2.5
2.5
—
—
—
0
0
70
446
1.46
2.37
1.6
1.6
—
—
—
0
0
634
5258
1.14
2.33
8.2
4.6
90.41
91.58
%
0.66
626
5134
88
588
1.39
2.31
1.2
1.2
—
—
—
0
0
148
1070
1.29
2.31
2.9
2.8
66.75
67.06
g/l
0.20
134
1004
415
3339
1.17
2.30
1.3
1.2
12.59
9.03
u/ml
0.26
167
1281
1213
10474
1.12
2.28
5.5
4.4
0.00
0.00
estimate
0.50
207
2021
52
314
1.54
2.28
1.3
1.3
—
—
—
0
0
682
5693
1.14
2.27
2.9
2.5
—
—
—
0
0
694
5802
1.14
2.26
4.4
3.5
8.10
8.48
mmol/l
1.15
600
5199
7
17
3.81
2.19
1.1
1.2
—
—
—
0
0
8
22
3.37
2.17
2.4
1.9
—
—
—
0
0
438
3563
1.16
2.12
1.3
1.3
16.65
26.95
iu/ml
3.25
135
1013
573
4751
1.14
2.11
3.0
2.4
—
—
—
0
0
68
443
1.43
2.09
15.1
6.8
—
—
—
0
0
420
3411
1.16
2.08
3.9
2.9
4.16
3.22
e6/l
0.74
237
1811
68
444
1.42
2.07
1.5
1.7
0.97
0.83
g/l
0.25
57
355
37
213
1.61
2.01
25.4
10.2
10.78
11.51
%
0.86
37
213
80
541
1.38
2.00
1.7
1.4
5.29
5.35
ug/l
0.01
73
503
47
287
1.52
2.00
4.1
3.3
1.30
1.23
%
0.09
41
266
2598
23470
1.14
1.97
10.6
8.7
26.40
26.39
u/l
0.00
2485
22724
112
799
1.31
1.97
4.2
2.6
—
—
—
0
0
91
631
1.34
1.95
3.1
3.2
—
—
—
0
0
32
179
1.66
1.95
1.0
1.0
—
—
—
0
0
695
5862
1.12
1.95
3.3
2.8
—
—
—
0
0
51
319
1.49
1.94
1.1
1.1
—
—
—
0
0
5
10
4.63
1.94
1.0
1.2
24.88
86.95
mg/l
—
5
10
46
282
1.52
1.93
1.1
1.2
0.91
25.95
u/ml
1.54
34
206
38
223
1.58
1.93
1.8
1.3
0.67
6.08
u/ml
4.73
24
142
25
133
1.74
1.83
2.8
1.8
5.46
4.47
nmol/l
0.47
25
128
5
11
4.21
1.81
1.6
2.2
—
—
—
0
0
7
21
3.08
1.80
1.6
1.5
—
—
—
0
0
428
3520
1.14
1.79
3.9
2.7
1.03
1.01
e6/l
0.05
246
1915
6
16
3.47
1.79
2.0
1.6
61.83
78.31
ng/l
—
6
16
196
1515
1.21
1.76
1.8
1.6
329.80
338.97
mu/l
0.12
180
1368
257
2039
1.18
1.74
2.0
1.4
—
—
—
0
0
263
2095
1.17
1.70
1.3
1.2
143.26
148.61
iu/ml
0.07
98
743
89
630
1.31
1.70
1.8
1.5
58.75
85.31
titre
—
8
64
247
1958
1.18
1.69
1.4
1.4
—
—
—
0
0
17
82
1.92
1.69
1.2
1.2
46.46
40.81
u/ml
—
7
12
2096
18770
1.10
1.68
3.9
3.4
5.58
5.66
mmol/l
2.06
1918
17367
34
202
1.56
1.67
4.8
4.4
—
—
—
0
0
14
63
2.06
1.67
1.3
1.5
—
—
—
0
0
169
1296
1.22
1.66
5.7
3.9
1.23
1.23
mmol/l
0.15
148
1129
115
845
1.27
1.66
1.3
1.2
—
—
—
0
0
73
506
1.34
1.62
1.2
1.2
—
—
—
0
0
216
1703
1.18
1.59
13.3
8.7
1.46
1.34
mmol/l
0.89
209
1665
28
161
1.61
1.58
4.3
3.1
49.37
53.43
%
0.45
23
144
112
827
1.26
1.57
13.3
12.0
—
—
—
0
0
29
170
1.58
1.53
1.9
1.5
—
—
—
0
0
181
1412
1.20
1.51
1.8
1.5
—
—
—
0
0
88
634
1.29
1.51
1.4
2.2
1.39
1.34
g/l
0.18
72
555
199
1568
1.18
1.49
1.9
1.8
1.08
1.21
g/l
1.41
189
1474
59
403
1.36
1.46
1.1
1.3
1.27
3.68
u/ml
1.49
40
229
355
2927
1.14
1.46
7.1
3.3
30.09
29.97
s
0.14
348
2862
46
301
1.42
1.46
1.2
1.3
—
21.20
—
0
13
98
720
1.27
1.45
1.1
1.1
7.22
8.01
u/ml
0.14
58
385
13
61
1.97
1.41
2.5
2.7
—
—
—
0
0
2404
21731
1.10
1.41
17.0
13.2
334.15
333.83
g/l
0.95
2381
21523
23
130
1.64
1.41
1.0
1.1
27.67
15.53
u/ml
—
6
25
78
560
1.29
1.39
1.2
1.3
2.60
17.36
u/ml
—
9
85
574
4882
1.11
1.39
3.8
3.2
1.02
1.02
kg/l
0.06
97
702
39
251
1.44
1.37
4.4
3.9
—
—
—
0
0
77
554
1.29
1.36
1.2
1.3
9.12
10.39
u/ml
—
6
57
509
4307
1.11
1.36
4.4
4.0
—
—
—
0
0
98
727
1.25
1.36
1.1
1.1
27.34
11.66
au/ml
—
7
41
120
911
1.23
1.35
1.1
1.1
2.44
6.68
u/ml
1.29
13
118
270
2202
1.15
1.33
1.4
1.4
—
—
—
0
0
198
1578
1.17
1.32
3.5
4.2
0.47
0.56
%
0.37
58
489
14
70
1.85
1.29
1.3
1.3
—
—
—
0
0
75
543
1.28
1.28
1.4
1.4
324.49
324.81
ug/g
0.00
45
282
104
785
1.23
1.25
7.0
7.7
25.00
24.29
mmol/l
1.30
96
748
146
1140
1.19
1.25
1.2
1.3
202.59
223.22
miu/ml
0.34
63
552
640
5501
1.09
1.25
3.8
3.4
0.01
0.00
estimate
0.10
199
1956
675
5816
1.09
1.25
4.6
3.2
0.20
0.35
e6/l
2.05
526
4322
12
58
1.92
1.22
1.1
1.2
—
—
—
0
0
501
4274
1.10
1.15
3.8
2.7
5.60
7.17
e6/l
1.97
457
3806
16
87
1.70
1.15
4.4
7.2
1.20
1.21
mmol/l
0.47
16
79
1611
14392
1.07
1.15
4.5
3.2
34.98
37.90
u/l
1.22
1512
13687
193
1555
1.16
1.15
4.0
4.6
0.00
0.27
%
0.76
50
406
110
846
1.21
1.13
1.3
1.2
0.39
0.87
u/ml
—
8
65
147
1582
0.85
1.12
1.3
1.3
—
—
—
0
0
27
169
1.48
1.12
1.4
1.3
—
—
—
0
0
16
88
1.68
1.11
1.9
1.3
77.06
78.05
nmol/24h
0.02
16
88
13
67
1.80
1.11
3.8
4.9
—
—
—
0
0
104
797
1.21
1.11
4.9
5.6
—
—
—
0
0
8
37
2.00
1.11
2.9
2.6
—
—
—
0
0
20
117
1.58
1.11
1.0
1.2
—
—
—
0
0
201
1631
1.15
1.10
4.0
4.5
0.03
0.10
%
1.83
61
484
419
4212
0.91
1.10
1.7
1.8
—
—
—
0
0
9
150
0.55
1.09
1.2
1.2
—
—
—
0
0
196
1591
1.15
1.07
10.3
9.1
14.30
13.51
kpa
1.00
185
1535
196
1592
1.15
1.06
10.3
9.1
5.14
5.14
kpa
0.01
185
1533
195
1584
1.15
1.06
10.3
9.2
1.00
0.68
mmol/l
0.59
156
1262
5
20
2.31
1.04
3.0
1.5
—
—
—
0
0
5
20
2.31
1.04
1.4
1.2
337.00
267.00
umol/24h
—
5
20
16
90
1.65
1.04
3.4
2.1
4.96
2.19
nmol/l
0.45
16
82
7
31
2.09
1.04
1.1
1.0
—
—
—
0
0
59
429
1.28
1.02
3.2
3.1
23.82
25.01
mg/l
0.09
39
273
24
150
1.48
1.02
1.1
1.2
1.09
1.05
ratio
—
6
64
31
204
1.41
1.02
1.2
1.3
—
—
—
0
0
21
128
1.52
1.00
1.1
1.1
—
—
—
0
0
561
4845
1.09
1.00
1.6
1.6
—
—
—
0
0
9
45
1.85
0.99
1.7
2.0
—
—
—
0
0
5
21
2.20
0.99
1.2
1.1
—
—
—
0
0
865
7600
1.07
0.98
5.3
3.8
57.07
70.43
e6/l
0.27
606
5110
724
6328
1.07
0.95
4.7
3.3
29.77
65.92
e6/l
1.51
567
4764
44
525
0.77
0.94
2.7
2.1
—
—
—
0
0
8
131
0.56
0.93
1.3
1.2
—
—
—
0
0
207
1706
1.13
0.93
4.0
4.5
0.57
0.87
%
1.45
68
560
46
329
1.30
0.92
7.0
4.7
—
—
—
0
0
14
79
1.64
0.91
1.7
1.2
—
—
—
0
0
14
79
1.64
0.91
1.7
1.2
—
—
—
0
0
14
79
1.64
0.91
1.7
1.2
—
—
—
0
0
175
1429
1.14
0.91
11.1
9.8
96.78
95.86
%
0.84
165
1386
6
26
2.13
0.91
1.7
3.2
24.67
3926.96
u/l
—
6
26
181
1482
1.14
0.91
2.2
2.4
4.52
5.50
e9/l
0.63
145
1279
42
298
1.31
0.90
5.0
2.5
70.11
74.67
mmol/l
0.26
37
263
154
1249
1.15
0.89
2.8
2.3
—
—
—
0
0
10
157
0.59
0.89
1.4
1.2
—
—
—
0
0
100
784
1.18
0.89
1.1
1.1
4.46
5.50
u/ml
0.32
64
461
554
4808
1.08
0.88
2.7
2.2
343.37
233.40
u/l
0.66
518
4596
54
622
0.80
0.88
1.3
1.1
—
—
—
0
0
54
620
0.80
0.86
1.3
1.1
—
—
—
0
0
117
933
1.17
0.86
2.8
2.7
26.39
44.96
u/ml
1.49
111
900
106
839
1.17
0.85
1.5
1.6
—
—
—
0
0
64
720
0.82
0.85
1.3
1.5
—
—
—
0
0
134
1081
1.15
0.84
2.2
2.1
13.21
7.45
ug/l
0.69
114
960
168
1377
1.13
0.84
4.0
3.2
—
—
—
0
0
6
29
1.91
0.83
9.2
7.7
—
—
—
0
0
12
176
0.63
0.83
1.1
1.2
—
—
—
0
0
2086
18903
1.06
0.82
4.3
3.6
4.60
4.65
mmol/l
1.86
1945
17919
12
175
0.63
0.81
1.3
1.2
—
—
—
0
0
18
112
1.49
0.81
1.0
1.4
—
76.33
%
—
0
12
20
128
1.45
0.79
3.4
2.7
—
—
—
0
0
0
22
0.00
0.79
0.0
1.0
—
0.08
—
0
15
22
144
1.41
0.78
4.6
2.2
34.75
78.90
ug/l
0.35
22
125
7
116
0.56
0.77
1.6
1.3
1.45
1.53
g/l
—
7
116
27
184
1.36
0.77
1.4
1.7
64.53
52.29
%
0.86
17
123
53
398
1.23
0.75
1.2
1.3
2.30
4.49
u/ml
2.43
23
189
132
1076
1.14
0.74
1.8
1.8
—
—
—
0
0
8
124
0.60
0.73
1.0
1.1
—
—
—
0
0
15
92
1.51
0.73
3.4
2.3
—
—
—
0
0
663
5838
1.06
0.71
4.5
3.1
—
—
—
0
0
64
704
0.84
0.71
1.3
1.5
—
—
—
0
0
5
24
1.93
0.70
3.8
4.0
4.52
4.46
mmol/l
—
5
24
5
24
1.93
0.70
1.6
2.3
—
—
—
0
0
9
53
1.57
0.70
2.2
1.5
—
—
—
0
0
16
101
1.47
0.69
1.1
1.1
—
—
—
0
0
9
54
1.54
0.69
1.0
1.0
—
—
—
0
0
30
213
1.30
0.68
2.4
2.0
—
—
—
0
0
39
287
1.26
0.68
1.4
1.6
—
—
—
0
0
64
700
0.84
0.67
1.3
1.5
—
—
—
0
0
17
110
1.43
0.66
3.1
2.9
65.52
92.43
umol/l
—
5
22
252
2521
0.92
0.66
1.3
1.3
—
—
—
0
0
5
26
1.78
0.65
5.4
3.5
1.98
1.84
mg/l
—
5
19
20
134
1.38
0.65
1.1
1.1
215.91
219.38
iu/ml
0.02
20
134
128
1324
0.89
0.64
1.5
1.6
—
—
—
0
0
33
384
0.79
0.64
2.1
2.4
—
—
—
0
0
13
80
1.50
0.64
2.4
2.3
—
—
—
0
0
50
383
1.21
0.62
1.3
1.3
6.98
12.16
u/ml
0.31
30
195
121
1253
0.89
0.62
1.4
1.4
—
—
—
0
0
32
233
1.27
0.62
1.1
1.1
—
—
—
0
0
13
81
1.49
0.61
1.8
1.9
—
—
—
0
0
42
317
1.23
0.60
1.1
1.1
1.51
1.45
g/l
0.56
36
292
79
633
1.16
0.60
1.1
1.1
1.13
0.34
u/ml
0.45
30
227
8
48
1.54
0.59
1.0
1.2
—
—
—
0
0
24
169
1.31
0.59
11.8
10.9
0.63
0.61
mmol/l
0.32
24
158
92
747
1.14
0.59
1.9
2.2
—
—
—
0
0
8
49
1.51
0.58
1.0
1.2
—
—
—
0
0
27
317
0.79
0.58
2.0
2.3
55.44
133.94
ug/min
0.75
11
203
6
33
1.68
0.57
1.0
1.0
163.00
166.79
g/l
—
6
33
6
33
1.68
0.57
8.0
9.4
—
—
—
0
0
52
406
1.19
0.55
1.1
1.1
—
—
—
0
0
10
60
1.54
0.55
9.0
5.4
—
—
—
0
0
41
313
1.21
0.54
1.1
1.1
0.46
2.38
u/ml
1.12
28
158
16
107
1.38
0.54
1.1
1.1
—
—
—
0
0
156
1316
1.10
0.54
9.4
9.6
125.07
122.85
g/l
0.69
148
1287
14
179
0.72
0.54
14.5
13.6
599.00
804.82
nmol/l
1.52
14
174
11
147
0.69
0.54
1.0
1.1
1328.23
1613.57
miu/ml
0.38
11
147
10
136
0.68
0.53
1.5
1.3
74.40
73.14
umol/l
—
10
136
562
4973
1.05
0.53
3.8
3.1
—
—
—
0
0
18
220
0.75
0.52
1.9
4.0
101.11
1366.51
u/ml
0.59
18
206
15
100
1.39
0.52
1.3
1.2
—
—
—
0
0
26
190
1.27
0.51
1.3
1.6
—
—
—
0
0
46
500
0.85
0.49
1.2
1.1
35.42
1025.62
iu/ml
0.62
12
147
47
369
1.18
0.48
1.6
1.7
7634.00
10705.34
e6/l
0.79
32
277
19
134
1.31
0.48
1.2
1.6
25.67
37.86
%
0.82
12
86
46
361
1.18
0.48
5.6
4.4
—
—
—
0
0
405
3565
1.06
0.47
1.7
1.6
—
—
—
0
0
156
1327
1.09
0.47
1.3
1.2
—
—
—
0
0
44
345
1.18
0.46
1.3
1.5
—
—
—
0
0
70
570
1.14
0.46
2.5
2.3
0.70
0.70
nmol/l
0.01
52
493
7
45
1.44
0.46
3.0
2.3
—
—
—
0
0
26
296
0.81
0.45
2.0
1.7
—
—
—
0
0
99
825
1.11
0.45
1.5
1.7
1.22
1.16
g/l
1.48
93
789
16
111
1.33
0.45
1.6
2.6
0.50
2.18
u/field
—
8
71
36
278
1.20
0.45
2.1
2.0
293.04
289.52
mosm/kgh2o
0.59
27
226
7
46
1.41
0.45
1.0
1.2
—
—
—
0
0
12
80
1.39
0.42
1.0
1.1
—
—
—
0
0
5
29
1.59
0.42
5.2
8.0
—
—
—
0
0
33
255
1.20
0.42
1.1
1.3
—
0.39
nmol/l
—
0
12
0
14
0.00
0.41
0.0
2.3
—
3.70
—
0
5
0
14
0.00
0.41
0.0
5.6
—
—
—
0
0
0
14
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
8
54
1.37
0.41
1.1
1.2
—
—
—
0
0
5
31
1.49
0.41
5.2
6.2
62.60
42.04
umol/l
—
5
25
5
31
1.49
0.41
1.6
1.3
—
—
—
0
0
11
73
1.39
0.40
1.2
1.6
—
—
—
0
0
724
6887
0.96
0.39
2.0
2.1
—
—
—
0
0
58
474
1.13
0.38
4.1
4.0
53.31
54.36
%
0.24
58
474
66
544
1.12
0.38
1.1
1.1
5.53
3.92
u/ml
0.32
20
197
358
3165
1.05
0.38
4.5
4.0
1.91
2.04
ug/l
0.14
318
2891
9
62
1.34
0.38
1.2
1.3
—
—
—
0
0
10
66
1.40
0.38
1.2
1.3
—
—
—
0
0
241
2110
1.06
0.37
1.8
1.8
—
—
—
0
0
23
174
1.22
0.36
1.3
1.3
192.18
228.66
pmol/l
0.28
23
174
248
2176
1.06
0.35
1.2
1.2
—
—
—
0
0
10
67
1.38
0.35
1.0
1.1
—
14.80
%
—
0
5
30
235
1.18
0.35
1.1
1.3
—
—
—
0
0
15
175
0.79
0.34
1.1
2.7
3.44
1.77
mmol/l
—
9
138
1351
12691
0.97
0.34
3.1
2.9
—
—
—
0
0
214
2086
0.94
0.34
2.4
2.3
2425.51
6651.21
u/l
2.36
64
678
78
656
1.10
0.33
1.2
1.2
—
—
—
0
0
6
42
1.32
0.33
1.0
1.1
—
—
—
0
0
6
42
1.32
0.33
1.0
1.1
—
—
—
0
0
6
42
1.32
0.33
1.0
1.1
—
—
—
0
0
20
151
1.23
0.33
5.5
2.6
—
—
—
0
0
30
237
1.17
0.32
1.2
1.3
12.95
19.12
u/ml
0.25
25
183
31
246
1.17
0.32
1.5
1.4
—
—
—
0
0
7
89
0.73
0.31
1.3
1.5
—
—
—
0
0
7
90
0.72
0.31
1.1
1.5
—
—
—
0
0
7
92
0.70
0.30
1.0
1.4
37.54
34.63
g/l
—
7
77
169
1475
1.06
0.30
1.2
1.3
49.79
44.62
au/ml
—
8
69
22
170
1.20
0.30
8.4
4.1
—
109.52
—
0
23
18
136
1.22
0.30
1.3
2.6
42.28
42.19
%
0.01
12
67
1970
18025
1.03
0.30
3.9
3.3
1.21
1.24
mmol/l
1.23
1820
16974
7
51
1.27
0.30
1.1
1.3
—
—
—
0
0
31
248
1.16
0.29
1.5
1.4
1.15
1.21
promille
0.06
25
195
229
2020
1.05
0.29
1.3
1.2
95.00
194.80
titre
—
9
64
58
591
0.91
0.29
2.1
2.0
5.43
4.74
iu/l
0.24
21
221
343
3056
1.04
0.29
4.2
3.3
1084.89
602.15
ng/l
0.43
205
1843
27
214
1.17
0.29
1.1
1.3
—
—
nmol/l
—
0
0
2045
18726
1.03
0.29
4.3
3.5
1.45
1.45
mmol/l
0.49
1900
17654
50
416
1.11
0.28
1.4
1.6
—
1253.33
—
0
9
73
621
1.09
0.27
3.8
2.3
200.73
669.49
e6/l
1.06
62
486
98
970
0.93
0.26
16.1
11.1
1.27
1.30
%
0.16
98
965
82
703
1.08
0.26
1.2
1.2
—
—
—
0
0
125
1089
1.06
0.25
3.0
2.4
—
—
—
0
0
16
122
1.21
0.25
1.1
1.1
—
—
—
0
0
9
69
1.21
0.25
1.1
1.4
—
8.94
%
—
0
18
94
812
1.07
0.25
1.1
1.1
—
—
—
0
0
182
1606
1.05
0.24
2.3
2.3
15.54
20.58
au/ml
0.41
16
137
27
218
1.15
0.24
1.0
1.2
—
—
—
0
0
49
497
0.91
0.24
1.5
2.3
139.55
133.83
g/l
0.84
42
399
14
156
0.83
0.23
2.8
4.2
86.44
237.54
umol/l
—
9
96
2073
19015
1.02
0.23
4.4
3.8
2.79
2.80
mmol/l
0.16
1926
17873
5
36
1.28
0.23
1.4
1.2
—
—
—
0
0
13
98
1.23
0.23
2.3
1.3
139.46
140.21
nmol/l
0.02
13
98
117
1142
0.94
0.22
3.1
4.2
4.28
22.81
ug/l
1.54
85
871
251
2402
0.96
0.22
2.2
1.8
—
—
—
0
0
22
233
0.87
0.21
1.2
1.6
—
—
—
0
0
46
388
1.10
0.21
1.1
2.1
10.48
10.13
g/l
0.25
38
366
215
1913
1.04
0.21
2.1
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
179.00
—
0
10
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
3.82
—
0
11
13
99
1.21
0.21
1.1
1.1
—
4.44
—
0
9
72
621
1.07
0.21
3.8
2.3
3.54
16.37
e6/l
3.05
59
469
16
125
1.18
0.21
1.3
1.2
—
46.98
—
0
12
12
134
0.83
0.21
1.5
1.5
0.88
1.00
g/l
0.80
12
134
0
13
0.00
0.20
0.0
1.2
—
4.69
—
0
7
174
1673
0.96
0.20
3.1
2.5
—
—
—
0
0
73
632
1.07
0.19
1.2
1.3
—
—
—
0
0
6
47
1.18
0.19
1.3
2.0
—
—
—
0
0
6
47
1.18
0.19
1.8
1.7
—
—
—
0
0
30
249
1.11
0.19
2.9
3.6
31.88
140.65
u/ml
—
10
70
17
135
1.16
0.19
4.9
2.9
986.18
898.42
u/ml
0.12
17
135
92
898
0.95
0.19
1.7
1.7
—
—
—
0
0
74
727
0.94
0.18
1.4
1.2
—
—
—
0
0
222
2119
0.97
0.18
1.5
1.5
—
—
—
0
0
13
101
1.19
0.18
4.9
7.0
—
—
—
0
0
33
277
1.10
0.18
1.9
1.9
—
—
—
0
0
68
591
1.06
0.17
3.9
2.4
—
—
—
0
0
23
189
1.13
0.17
3.2
2.9
36370.26
40297.22
ug/l
0.78
23
189
23
189
1.13
0.17
1.2
1.4
1.49
1.82
mmol/l
4.27
23
178
12
131
0.85
0.17
1.3
1.4
—
—
—
0
0
67
583
1.06
0.16
3.0
2.7
355.40
375.51
ug/l
0.07
60
532
33
279
1.09
0.16
1.2
1.4
—
—
—
0
0
25
208
1.11
0.16
1.2
1.4
10.08
10.68
umol/l
0.20
25
200
37
315
1.09
0.15
3.6
2.3
—
—
—
0
0
6
70
0.79
0.15
2.0
2.8
—
—
—
0
0
11
120
0.85
0.15
1.9
2.9
0.88
0.88
nmol/l
—
5
95
30
253
1.10
0.15
1.5
1.3
566.00
186.36
titre
—
5
11
30
253
1.10
0.15
1.5
1.3
356.00
216.03
titre
—
5
58
804
7336
1.02
0.15
2.8
2.3
—
—
—
0
0
22
226
0.90
0.15
2.1
1.9
—
—
—
0
0
25
209
1.11
0.15
1.0
1.0
—
—
—
0
0
7
79
0.82
0.14
2.3
3.0
—
—
—
0
0
61
596
0.94
0.14
8.8
5.4
—
—
—
0
0
423
3979
0.98
0.14
3.5
3.4
752.50
260.42
mg/l
0.84
261
2724
39
387
0.93
0.14
2.0
2.8
18.47
17.36
%
1.33
18
215
8
90
0.82
0.13
6.0
4.8
—
—
—
0
0
8
90
0.82
0.13
3.0
2.4
—
—
—
0
0
14
147
0.88
0.13
2.7
2.7
0.60
1.61
g/24h
—
6
89
48
471
0.94
0.13
4.9
4.3
1.20
1.38
mmol/l
1.29
48
462
26
220
1.09
0.13
1.7
1.5
—
—
—
0
0
37
319
1.07
0.12
1.4
1.4
6.30
7.02
mmol/l
0.96
32
286
39
337
1.07
0.12
1.1
2.1
38.79
38.62
g/l
0.06
30
316
20
204
0.91
0.12
1.6
1.6
—
—
—
0
0
249
2251
1.02
0.12
2.1
1.9
—
—
—
0
0
17
175
0.90
0.12
1.2
1.2
—
—
—
0
0
28
280
0.92
0.12
1.7
1.6
—
—
—
0
0
257
2424
0.98
0.11
2.2
1.9
—
—
—
0
0
10
79
1.17
0.11
1.1
1.3
—
—
—
0
0
10
107
0.86
0.11
1.0
1.0
—
—
—
0
0
30
298
0.93
0.11
2.9
3.6
26.89
80.52
mg/l
1.43
24
243
30
298
0.93
0.11
2.9
3.6
28.19
31.18
mg/l
0.21
24
245
101
966
0.97
0.11
15.9
11.3
95.50
94.36
%
1.36
101
961
101
966
0.97
0.11
15.9
11.2
0.75
0.70
%
0.66
101
961
23
195
1.09
0.11
1.5
1.2
—
—
—
0
0
49
430
1.05
0.10
1.1
1.1
—
—
—
0
0
11
115
0.88
0.09
1.2
2.5
50.09
68.70
nmol/l
1.95
11
110
23
197
1.08
0.09
7.0
4.0
—
—
—
0
0
196
1847
0.98
0.09
3.6
3.5
—
—
—
0
0
22
219
0.93
0.09
3.5
3.8
—
—
—
0
0
50
442
1.05
0.08
6.4
4.0
—
—
—
0
0
6
54
1.03
0.08
2.3
3.1
—
—
—
0
0
15
152
0.91
0.08
1.0
1.2
—
—
—
0
0
13
108
1.11
0.08
1.3
1.4
—
—
—
0
0
19
162
1.08
0.08
1.8
1.9
—
—
—
0
0
44
424
0.96
0.07
1.1
1.1
—
—
—
0
0
18
154
1.08
0.07
1.4
1.4
303310.89
71271.85
e6/l
—
9
110
60
536
1.04
0.07
7.4
7.8
—
—
—
0
0
11
91
1.12
0.07
1.1
1.3
—
—
—
0
0
9
80
1.04
0.07
1.1
1.5
—
—
—
0
0
16
160
0.92
0.06
1.1
1.0
27.72
20.27
u/ml
—
6
96
283
2647
0.99
0.06
2.2
2.6
2.43
2.43
mmol/l
0.03
238
2321
443
4131
0.99
0.06
4.2
4.0
11.31
14.07
mg/mmol
0.24
268
2773
262
2451
0.99
0.06
2.2
1.9
—
—
—
0
0
551
5130
0.99
0.06
1.7
1.7
—
—
—
0
0
41
394
0.96
0.06
1.1
1.1
—
—
—
0
0
787
7232
1.01
0.06
1.5
1.6
—
—
—
0
0
41
365
1.04
0.05
5.9
3.0
—
—
—
0
0
10
102
0.91
0.05
1.4
1.4
145.90
160.66
mmol/24h
—
10
102
39
374
0.96
0.05
1.3
1.3
—
—
—
0
0
262
2445
0.99
0.05
2.1
1.9
—
—
—
0
0
124
1130
1.01
0.04
1.0
1.1
—
—
—
0
0
11
110
0.92
0.03
1.0
1.1
44.67
4.69
u/ml
—
6
57
23
221
0.96
0.03
7.5
3.8
6.54
6.57
mmol/l
0.02
17
189
52
490
0.98
0.02
2.7
2.0
4.02
2.29
ug/l
0.40
47
442
201
1869
0.99
0.02
2.8
2.6
0.64
0.70
ug/l
0.63
101
1081
10
87
1.06
0.00
1.1
1.5
4960.00
25617.49
e6/l
—
5
47
204
1879
1.00
0.00
2.7
2.3
31.22
62.41
u/l
0.65
176
1604
69
632
1.01
0.00
3.8
2.1
3.61
3.52
mmol/l
0.39
69
597
12
107
1.04
0.00
1.7
2.3
15.13
17.16
umol/l
0.30
12
107
11
105
0.97
0.00
2.5
2.3
—
—
—
0
0
51
475
0.99
0.00
3.1
3.4
18.31
3009.57
u/ml
0.80
45
405
74
687
1.00
0.00
3.9
2.1
428.24
446.74
mg/l
0.06
74
658
23
212
1.00
0.00
1.4
1.6
—
—
—
0
0
18
169
0.98
0.00
1.1
1.1
—
—
—
0
0
17
161
0.98
0.00
1.0
1.0
—
—
—
0
0
132
1221
1.00
0.00
1.5
1.4
—
—
—
0
0
11
100
1.02
0.00
1.1
1.4
2336.83
4425.58
e6/l
—
6
64
45
417
1.00
0.00
10.6
4.4
1.82
2.10
mmol/l
0.43
31
246
12
111
1.00
0.00
1.0
1.1
0.01
2.23
u/ml
—
6
59
11
101
1.01
0.00
2.0
2.2
541.40
610.13
ml
—
5
68
6
63
0.88
0.00
1.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
48
0.96
-0.00
1.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
496.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
687.32
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
0.94
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_CROSSBITE and mortality.

Females

Parameter HR [95% CI] p-value
K11_CROSSBITE 0.68 [0.47, 0.99] 0.043
Birth year 0.992 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 46029 females with K11_CROSSBITE died.

Males

Parameter HR [95% CI] p-value
K11_CROSSBITE 0.639 [0.41, 0.99] 0.046
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 42490 males with K11_CROSSBITE died.

Mortality risk

Mortality risk for people of age

years, who have K11_CROSSBITE.

N-year risk Females Males
1 0.064% 0.144%
5 0.355% 0.823%
10 0.863% 2.111%
15 1.726% 3.989%
20 2.946% 6.681%

Relationships between endpoints

Index endpoint: K11_CROSSBITE – Crossbite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data