Septal defects

Q17_SEPTA_DEFEC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q21.0, Q21.10, Q21.11, Q21.12, Q21.13, Q21.18, Q21.19, Q21.88, Q21.9
  • Hospital discharge: ICD-9 7454E|7454X|7454A|7455A|7456X|7456A|7458X|7459X
  • Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 758|7595|75683
  • Cause of death: ICD-10 Q21.0, Q21.10, Q21.11, Q21.12, Q21.13, Q21.18, Q21.19, Q21.88, Q21.9
  • Cause of death: ICD-9 7454E|7454X|7454A|7455A|7456X|7456A|7458X|7459X
  • Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 758|7595|75683

2 out of 7 registries used, show all original rules.

2622

4. Check minimum number of events

None

2622

5. Include endpoints

None

2622

6. Filter based on genotype QC (FinnGen only)

2512

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37758 20128 17561
Only index persons 24425 13039 11386
Unadjusted period prevalence (%)
Whole population 0.54 0.58 0.49
Only index persons 0.46 0.48 0.43
Median age at first event (years)
Whole population 0.53 0.50 0.42
Only index persons 3.90 4.73 2.96

-FinnGen-

Key figures

All Female Male
Number of individuals 2512 1506 1006
Unadjusted period prevalence (%) 0.50 0.53 0.46
Median age at first event (years) 40.62 37.37 45.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2619
Matched controls
25631
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B01AA03
ATC
warfarin; systemic
5.9
307.7
730
1577
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
565.0
307.7
352
7
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
28.5
307.7
1034
573
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
307.7
527
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
11681.9
307.7
835
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.8
307.7
1275
3155
XF620
NOMESCO Finland
Examination of circulation with color method
149.0
307.7
273
20
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
307.7
342
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
5036.8
307.7
442
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
307.7
369
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
11805.6
307.7
841
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
12.3
307.7
373
342
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
7.0
307.7
984
2031
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
15.4
294.4
269
189
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
7.4
291.8
480
758
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
8.4
280.1
403
546
31
HP
Congenital heart failure surgery
113.8
274.4
143
13
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
28.3
255.1
176
65
201
Kela drug reimbursment
Chronic cardiac insufficiency
9.4
234.1
298
345
XF400
NOMESCO Finland
ECG with 12 standard connections
4.2
220.6
759
2262
XF404
NOMESCO Finland
Ambulatory ECG
5.3
196.2
446
949
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
185.8
1435
7024
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
181.0
173
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.1
179.0
429
952
FM2CE, ,
NOMESCO Finland
7.1
136.1
217
324
62
HP
Catheterization and pressure measurement of the right side of the heart
52.4
133.6
78
15
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.5
132.3
546
1786
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
6.2
124.7
227
388
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
10.1
124.1
145
148
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
124.0
119
*
Q25.1
ICD-10 Finland
Coarctation of aorta
24.7
122.3
88
36
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
121.4
590
2126
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
120.8
116
*
C01AA05
ATC
digoxin; systemic
5.6
120.5
245
465
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
+∞
118.7
114
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
15.5
117.2
104
68
Q21.0
ICD-10 Finland
Ventricular septal defect
301.4
115.1
117
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.3
113.6
324
815
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
6.3
101.4
179
296
5253
FHL
Cardiac lung machine
26.4
101.1
71
27
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
211.9
100.4
104
5
TFP20
NOMESCO Finland
Cardiodefibrillation
4.6
98.1
248
566
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
36.5
97.6
62
17
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
96.8
405
1320
C03CA01
ATC
furosemide; systemic
2.7
96.7
660
2830
61
HP
Catheterization and pressure measurement of the left side of the heart
12.3
95.6
97
80
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
92.5
89
*
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
20.4
91.4
71
35
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.8
90.9
551
2215
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
35.6
89.1
57
16
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
87.6
875
4459
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
12.1
87.2
89
74
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.4
86.2
115
139
AA1AD
NOMESCO Finland
CT of head and brain
2.5
86.0
700
3247
WX872
NOMESCO Finland
Intensive care
5.0
85.9
196
410
Q23.11
ICD-10 Finland
Bicuspid aortic valve
10.8
84.4
93
87
XF402
NOMESCO Finland
ECG with work load test
3.4
83.3
331
1040
XF622
NOMESCO Finland
Measurement of minute volume of heart
23.1
81.3
60
26
B01AC04
ATC
clopidogrel; oral
3.0
80.9
401
1437
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
4.1
80.0
233
591
PA2AE
NOMESCO Finland
Ultrasound examination of brain artery
119.8
76.7
83
7
5205
FHL
ASD blockage, secondary defect
+∞
75.8
73
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
4.3
75.7
205
492
XA800
NOMESCO Finland
Neuropsychological investigation
3.6
73.9
266
782
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
191.4
72.9
76
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
13.1
70.9
69
53
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.1
69.1
327
1136
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
7.1
68.6
105
149
WX892
NOMESCO Finland
Monitored bed care
3.3
68.5
290
943
I50.9
ICD-10 Finland
Heart failure, unspecified
3.2
67.9
292
959
C03DA01
ATC
spironolactone; oral
3.0
67.8
326
1143
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
67.5
65
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
4.7
67.4
164
361
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
14.5
63.3
58
40
R4150
NOMESCO Finland
Neuropsychological rehabilitation
10.5
63.3
71
68
XF640, ,
NOMESCO Finland
6.4
63.2
108
172
207
Kela drug reimbursment
Chronic arrhythmias
2.8
62.7
344
1295
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.3
62.2
167
397
I34.1
ICD-10 Finland
Mitral (valve) prolapse
6.3
62.2
108
175
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
61.8
964
5702
C07AB07
ATC
bisoprolol; oral
2.0
60.9
1018
6165
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
60.7
681
3554
K78
ICPC
Atrial fibrillation/flutter
3.8
60.3
194
527
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
5.4
60.3
122
229
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.3
60.2
163
390
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
12.5
59.2
59
47
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
58.6
1047
6466
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
58.2
415
1779
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
57.0
55
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
6.7
55.4
89
133
XF600
NOMESCO Finland
Bloodpressure measurement
2.9
55.3
287
1045
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.4
55.2
216
667
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
4.9
54.2
123
255
Q21.1
ICD-10 Finland
Atrial septal defect
+∞
52.9
51
*
FFC50
NOMESCO Finland
Closure of ostium secundum type ASD using patch
+∞
51.8
50
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
50.9
192
579
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
486.5
49.1
49
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
6.8
48.7
78
116
APK
HP
ASD closure
+∞
48.7
47
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
12.7
46.6
46
36
Q21.30
ICD-10 Finland
Tetralogy of Fallot
15.9
45.9
40
25
5207
FHL
VSD closure
+∞
45.6
44
*
AA5PD
NOMESCO Finland
CT examination of brain pefusion
10.4
45.3
51
49
I50.0
ICD-10 Finland
Congestive heart failure
3.7
44.9
151
422
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.3
44.8
118
276
APJ
HP
PFO closure
+∞
44.6
43
*
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
16.4
44.3
38
23
AF1
HP
Surgery of congenital heart defect
223.9
43.7
45
*
K90
ICPC
Stroke/cerebrovascular accident
5.2
43.6
92
179
C01BD01
ATC
amiodarone; systemic
5.3
43.1
89
170
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
43.0
623
3515
I63
ICD-10 Finland
Cerebral infarction
12.6
42.4
42
33
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.6
42.2
69
105
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
145.9
41.5
44
*
I49.5
ICD-10 Finland
Sick sinus syndrome
4.6
41.5
101
222
Q21.12
ICD-10 Finland
Defective sinus venosus
+∞
41.4
40
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
41.0
310
1354
WX402
NOMESCO Finland
General anaesthesia
1.9
40.3
647
3766
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.7
40.1
96
208
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.4
40.1
306
1341
ZXE00
NOMESCO Finland
One hour or less
1.8
39.9
1049
7082
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
15.1
39.1
35
23
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.3
38.7
155
484
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
38.6
348
1637
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
38.6
561
3154
Z2221
NOMESCO Finland
Medical doctor
1.8
38.4
751
4641
B01AB05
ATC
enoxaparin; parenteral
1.9
38.1
666
3974
WX882
NOMESCO Finland
High dependency care
2.9
38.1
191
680
C07AA07
ATC
sotalol; systemic
4.4
37.9
96
218
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.8
37.5
86
180
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
5.5
37.2
73
133
R4110
NOMESCO Finland
Physiotherapy
1.8
36.5
731
4538
7456A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM NUD]
+∞
36.2
35
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.0
35.7
103
258
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
14.2
35.6
33
23
Q21.21
ICD-10 Finland
Atrioventricular duct
79.6
35.5
40
5
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
10.5
34.9
39
37
Q20.1
ICD-10 Finland
Double outlet right ventricle
94.4
34.5
38
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
9.2
32.7
40
43
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.3
32.3
262
1176
K84
ICPC
Heart disease other
4.6
31.9
77
168
R4120
NOMESCO Finland
Occupational therapy
2.4
31.3
224
951
I48.4
ICD-10 Finland
Atypical atrial flutter
11.7
30.9
32
27
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
30.8
429
2360
C10AA05
ATC
atorvastatin; oral
1.7
30.5
746
4858
R06.0
ICD-10 Finland
Dyspnoea
1.8
30.3
592
3620
B01AF02
ATC
apixaban; oral
2.3
29.5
233
1033
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.6
29.4
98
272
ZXD05
NOMESCO Finland
Urgent procedure
1.7
28.3
733
4830
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
27.9
27
*
G04BE03
ATC
sildenafil; oral
5.3
27.2
55
103
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
46.7
27.2
33
7
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.1
27.0
117
383
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
6.8
26.8
42
61
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
74.3
26.5
30
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
95.7
26.4
29
*
I44.2
ICD-10 Finland
Atrioventricular block, complete
4.1
26.0
72
175
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
10.2
25.6
29
28
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.1
25.4
245
1177
RS224, ,
NOMESCO Finland
5.3
25.0
50
93
C09AA05
ATC
ramipril; oral
1.8
24.8
436
2568
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
24.7
245
1190
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
89.0
24.5
27
*
TFP34
NOMESCO Finland
Electrophysiological investigation
3.3
24.4
94
287
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
6.8
24.3
38
55
I37.0
ICD-10 Finland
Pulmonary valve stenosis
42.4
24.3
30
7
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.0
24.2
295
1545
PD5BD
NOMESCO Finland
Extensive CT of aorta
5.6
24.0
46
82
Q26.1
ICD-10 Finland
Persistent left superior vena cava
55.4
23.8
28
5
R04.0
ICD-10 Finland
Epistaxis
2.4
23.8
176
757
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
6.3
23.7
40
63
Z3231
NOMESCO Finland
Registered nurse
1.6
23.7
749
5147
R42
ICD-10 Finland
Dizziness and giddiness
1.7
23.4
475
2913
I48.2
ICD-10 Finland
Chronic atrial fibrillation
3.3
23.3
89
270
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
23.2
103
342
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
5.0
23.0
50
100
C07AB02
ATC
metoprolol; systemic
1.8
22.9
359
2039
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
22.8
572
3709
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
35.9
22.8
29
8
H53.4
ICD-10 Finland
Visual field defects
4.0
22.7
64
158
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
5.6
22.7
43
76
PA6AD
NOMESCO Finland
CT of neck arteries
3.5
22.4
79
228
AP2
HP
Catheterization of the right side of the heart
22.6
22.3
32
14
602
Kela drug reimbursment
Children's severe malnutrition
3.6
22.0
74
207
Q90.9
ICD-10 Finland
Down syndrome, unspecified
51.4
21.9
26
5
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
217.0
21.4
22
*
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
42.8
21.2
26
6
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
3.0
21.0
94
314
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.3
20.9
54
125
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.6
20.8
124
482
WW502
NOMESCO Finland
Autotransfusion
8.9
20.7
26
29
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.2
20.4
54
127
J01CA04
ATC
amoxicillin; systemic
1.7
20.4
2210
19535
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.7
20.4
64
171
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
16.7
20.2
32
19
AP3
HP
Catheterization of the right and left side of the heart
25.2
20.2
28
11
Z31.5
ICD-10 Finland
Genetic counselling
2.1
20.1
188
891
UGC02
NOMESCO Finland
Rigid bronchoscopy
6.2
20.0
34
54
FFC32
NOMESCO Finland
Percutaneous transluminal closure of sinus venosus type ASD
+∞
19.7
19
*
90492, ,
NOMESCO Finland
72.5
19.5
22
*
TFP35
NOMESCO Finland
Electroanatomical mapping
4.5
19.4
48
107
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
197.2
19.4
20
*
K83
ICPC
Heart valve disease NOS
6.0
19.3
34
56
Q20.48
ICD-10 Finland
Single ventricle
25.7
18.9
26
10
AN1
HP
Coronary angiography
2.1
18.9
182
873
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
6.6
18.6
30
45
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
18.5
383
2350
FFC40
NOMESCO Finland
Closure of Patent Foramen Ovale
187.2
18.4
19
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.2
18.3
158
726
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
18.1
67
200
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.7
18.0
95
347
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
19.1
18.0
27
14
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
6.1
17.9
31
50
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
51.8
17.8
21
*
WX704
NOMESCO Finland
Intubation
2.0
17.7
191
955
I48.1
ICD-10 Finland
Persistent atrial fibrillation
3.1
17.7
73
233
R62.0
ICD-10 Finland
Delayed milestone
2.8
17.6
91
329
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
17.6
17
*
7454X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD ALIA DEFINITA]
+∞
17.6
17
*
FFC96
NOMESCO Finland
Other closure of isolated atrial septal defect
+∞
17.6
17
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
28.4
17.2
23
8
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.0
17.1
77
258
I50.1
ICD-10 Finland
Left ventricular failure
2.8
17.1
85
301
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
62.4
16.6
19
*
Q87.14
ICD-10 Finland
Noonan's syndrome
34.5
16.5
21
6
81
HP
Angiography of the heart and coronary arteries
2.6
16.4
94
359
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.7
16.3
51
136
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
5.7
16.2
30
52
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.4
16.1
58
170
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
16.1
477
3190
C01BD07
ATC
dronedarone; oral
7.2
16.1
24
33
I47.2
ICD-10 Finland
Ventricular tachycardia
3.7
16.1
50
133
Z3226
NOMESCO Finland
Physiotherapist
1.6
15.9
475
3181
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
12.6
15.9
28
22
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
18.2
15.8
24
13
342
Kela drug reimbursment
Dronedarone
6.4
15.7
26
40
F83
ICD-10 Finland
Mixed specific developmental disorders
2.8
15.7
79
282
250, ,
Kela drug reimbursment
4.9
15.7
34
68
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.8
15.6
76
267
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
32.9
15.6
20
6
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
15.5
15
*
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
15.5
15
*
51
HP
Other heart surgery
83.8
15.4
17
*
FHB00
NOMESCO Finland
Transatrial suture of VSD
157.5
15.4
16
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
15.3
722
5311
Q22.0
ICD-10 Finland
Pulmonary valve atresia
37.5
15.2
19
5
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
5.3
15.0
30
56
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
15.0
1067
8445
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.7
14.9
46
122
FM1CD
NOMESCO Finland
Very extensive CT of heart
13.7
14.8
25
18
C01BC04
ATC
flecainide; systemic
2.8
14.8
75
269
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
14.7
227
1279
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
31.2
14.6
19
6
I27.0
ICD-10 Finland
Primary pulmonary hypertension
18.1
14.5
22
12
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
18.1
14.5
22
12
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
3.8
14.4
43
111
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.1
14.4
39
94
Q20.40
ICD-10 Finland
Double inlet left ventricle
147.6
14.3
15
*
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
4.4
14.2
35
78
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.0
14.2
40
99
FM1AD
NOMESCO Finland
CT of heart
15.1
14.2
23
15
Q25.40
ICD-10 Finland
Aortic hypoplasia
16.7
14.1
22
13
K80
ICPC
Cardiac arrhythmia NOS
2.0
14.1
163
836
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
5.3
14.0
28
52
R47.0
ICD-10 Finland
Dysphasia and aphasia
5.3
14.0
28
52
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
5.3
14.0
28
52
I97.0
ICD-10 Finland
Postcardiotomy syndrome
13.2
14.0
24
18
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
41.8
14.0
17
*
P85
ICPC
Mental retardation
4.2
13.9
37
88
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
13.8
97
408
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
13.7
718
5365
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
29.5
13.7
18
6
R4130
NOMESCO Finland
Speech therapy
2.4
13.7
97
410
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
13.7
144
714
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
19.7
13.6
20
10
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.8
13.6
223
1278
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
10.3
13.5
26
25
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
13.4
13
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
13.4
189
1035
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.7
13.4
69
250
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.3
13.3
34
78
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
137.7
13.3
14
*
K91
ICPC
Cerebrovascular disease
4.5
13.3
32
70
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
13.3
184
1001
K89
ICPC
Transient cerebral ischaemia
5.6
13.3
25
44
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
25.3
13.2
18
7
Q22.5
ICD-10 Finland
Ebstein anomaly
39.3
13.0
16
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
12.9
359
2359
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
12.9
1776
19096
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
5.2
12.8
26
49
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
27.9
12.8
17
6
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
4.8
12.7
28
57
R50.9
ICD-10 Finland
Fever, unspecified
1.5
12.7
419
2859
ZX199
NOMESCO Finland
Other rote
4.7
12.7
29
61
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
12.4
294
1858
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
12.1
12.4
22
18
FHB96
NOMESCO Finland
Other closure of congenital ventricular septal defect
+∞
12.4
12
*
Q21.2
ICD-10 Finland
Atrioventricular septal defect
+∞
12.4
12
*
I51.0
ICD-10 Finland
Cardiac septal defect, acquired
+∞
12.4
12
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
17.0
12.4
19
11
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
12.3
213
1240
7AX01, ,
NOMESCO Finland
9.9
12.3
24
24
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.1
12.3
50
159
K99
ICPC
Cardiovascular disease other
3.2
12.1
48
150
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.8
12.1
171
937
I48.3
ICD-10 Finland
Typical atrial flutter
4.9
12.0
26
52
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
15.6
12.0
19
12
I49.1
ICD-10 Finland
Atrial premature depolarization
2.5
12.0
75
300
ZXY02
NOMESCO Finland
Neuropsychologist
4.6
12.0
28
60
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
12.0
124
612
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
4.0
12.0
34
85
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.8
11.9
36
94
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
26.2
11.9
16
6
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
17.7
11.9
18
10
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
20.9
11.9
17
8
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.5
11.8
40
113
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
45.9
11.8
14
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
10.3
11.6
22
21
C02KX01
ATC
bosentan; oral
29.5
11.5
15
5
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
16.1
11.5
18
11
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
63.8
11.5
13
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
63.8
11.5
13
*
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
5.7
11.5
21
36
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
22.5
11.4
16
7
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
11.4
11
*
APX
HP
Other cardiac catheter operation
+∞
11.4
11
*
Q21
ICD-10 Finland
Congenital malformations of cardiac septa
+∞
11.4
11
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
118.0
11.3
12
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.1
11.2
45
142
R1260
NOMESCO Finland
Evaluation of communicative skills
2.8
11.1
54
190
UDC00
NOMESCO Finland
Ear microscopy
1.7
11.1
187
1081
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.8
11.1
55
196
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
11.1
542
3983
R00.2
ICD-10 Finland
Palpitations
1.8
11.0
178
1016
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
2.9
10.9
49
165
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.8
10.8
52
182
H52.2
ICD-10 Finland
Astigmatism
2.3
10.7
77
328
FPK00
NOMESCO Finland
Implantation of electrocardiograph with loop recorder
5.2
10.7
22
42
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
10.7
123
630
P07.3
ICD-10 Finland
Other preterm infants
2.6
10.6
61
235
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
59.0
10.5
12
*
Q90
ICD-10 Finland
Down syndrome
59.0
10.5
12
*
Q21.3
ICD-10 Finland
Tetralogy of Fallot
59.0
10.5
12
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
10.5
414
2922
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
13.9
10.3
17
12
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
10.3
10
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
10.3
10
*
5609
FHL
Other measure in this category
+∞
10.3
10
*
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
10.3
10
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
108.1
10.3
11
*
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
4.1
10.3
28
68
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
31.9
10.2
13
*
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
15.7
10.2
16
10
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
4.2
10.2
27
64
B01AE07
ATC
dabigatran etexilate; oral
2.5
10.2
64
257
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
3.4
10.2
36
105
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
4.3
10.2
26
60
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
8.6
10.1
21
24
Z2446
NOMESCO Finland
Social worker
1.6
10.0
239
1513
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
3.5
10.0
33
92
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.5
10.0
61
242
WX002
NOMESCO Finland
Sedation and analgesia
1.5
9.9
363
2521
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
9.9
129
689
K77
ICPC
Heart failure
3.4
9.9
35
102
M41.9
ICD-10 Finland
Scoliosis, unspecified
3.1
9.8
39
123
Q25.3
ICD-10 Finland
Stenosis of aorta
16.4
9.7
15
9
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
25.6
9.7
13
5
Q24.6
ICD-10 Finland
Congenital heart block
25.6
9.7
13
5
Q24.0
ICD-10 Finland
Dextrocardia
25.6
9.7
13
5
C08DA01
ATC
verapamil; systemic
2.3
9.7
75
331
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.1
9.7
89
421
FM1BD
NOMESCO Finland
Extensive CT of heart
8.0
9.7
21
26
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
8.0
9.7
21
26
B01AF01
ATC
rivaroxaban; oral
1.7
9.6
196
1192
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
9.6
232
1474
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
3.7
9.5
30
81
1EA01, ,
NOMESCO Finland
14.8
9.4
15
10
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
98.3
9.3
10
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
98.3
9.3
10
*
7454E
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD MULTIPLEX]
+∞
9.3
9
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
17.2
9.3
14
8
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
9.3
371
2621
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
7.4
9.2
21
28
SPAT1097
SPAT
Recording of ECG
1.6
9.2
237
1526
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
9.2
143
809
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
9.3
9.1
18
19
RS221, ,
NOMESCO Finland
2.5
9.1
55
217
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
9.0
105
541
3A064, ,
NOMESCO Finland
11.2
8.9
16
14
H01AC01
ATC
somatropin; parenteral
2.6
8.9
51
196
B01AC07
ATC
dipyridamole; systemic
2.6
8.9
51
196
74629
ICD-8 Finland
Congenital anomalies of heart, Tetralogy of Fallot
36.0
8.9
11
*
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
4.2
8.8
23
54
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
18.3
8.8
13
7
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
23.6
8.8
12
5
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.0
8.7
37
121
ZX108
NOMESCO Finland
Inhalation
3.4
8.7
31
91
SPAT1263
SPAT
Sampling
1.3
8.7
932
7667
73
HP
Initial pacemaker installation
10.5
8.7
16
15
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
4.1
8.6
23
55
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.6
171
1034
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
49.1
8.6
10
*
AC4
HP
MVP
13.8
8.6
14
10
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
2.3
8.6
65
285
XF405
NOMESCO Finland
Symptom ECG
3.7
8.5
26
69
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.7
8.4
154
911
D68.8
ICD-10 Finland
Other specified coagulation defects
3.3
8.4
31
93
I44.0
ICD-10 Finland
Atrioventricular block, first degree
3.6
8.4
27
74
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
8.4
471
3525
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
27.0
8.4
11
*
AD1
HP
TVP
27.0
8.4
11
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
27.0
8.4
11
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
19.7
8.4
12
6
FGE10
NOMESCO Finland
Replacement of tricuspid valve using biological prosthesis
88.4
8.3
9
*
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.3
8.3
21
48
SPAT1260
SPAT
Consultation of another employee
1.4
8.3
357
2552
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
3.9
8.3
24
61
GD1LA
NOMESCO Finland
GD
3.1
8.3
33
104
5501
FHL
Pulmonary artery stenosis
+∞
8.3
8
*
4168X
ICD-9 Finland
Chronic pulmonary heart disease, Other chronic pulmonary heart diseases
+∞
8.3
8
*
WZC30
NOMESCO Finland
Teaching
1.5
8.3
291
2005
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
7.7
8.2
18
23
R07.2
ICD-10 Finland
Precordial pain
2.7
8.2
44
164
XG460
NOMESCO Finland
Short time oxymetry
3.2
8.2
32
100
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
9.3
8.1
16
17
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.1
8.1
76
363
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
3.4
8.1
28
81
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
8.0
1304
11258
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
7.9
186
1173
I63.8
ICD-10 Finland
Other cerebral infarction
4.1
7.9
21
50
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
21.6
7.9
11
5
Q20.00
ICD-10 Finland
Common arterial trunk
21.6
7.9
11
5
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
21.6
7.9
11
5
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.6
7.9
43
162
71
HP
Electrophysiological Special Examination
4.7
7.9
18
38
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
7.8
56
240
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.0
7.8
87
443
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.1
7.7
71
337
C09AA02
ATC
enalapril; systemic
1.5
7.7
275
1899
K92.1
ICD-10 Finland
Melaena
1.9
7.7
87
445
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
7.7
167
1034
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
7.7
373
2725
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.8
7.7
121
688
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
9.2
7.7
15
16
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
44.1
7.6
9
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
14.7
7.6
12
8
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
7.6
192
1232
ZXA10
NOMESCO Finland
Bilateral
1.4
7.5
366
2674
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
18.0
7.5
11
6
4302
FHL
Tooth patching under general anesthesia
18.0
7.5
11
6
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
24.5
7.5
10
*
FB1BC
NOMESCO Finland
Extensive angiography of arteria pulmonalis
24.5
7.5
10
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
24.5
7.5
10
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.8
7.5
117
664
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.5
824
6773
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
9.8
7.4
14
14
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
9.8
7.4
14
14
H81.3
ICD-10 Finland
Other peripheral vertigo
2.4
7.4
50
209
PD5AD
NOMESCO Finland
CT of aorta
2.6
7.4
41
156
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
78.6
7.4
8
*
Q25.70
ICD-10 Finland
Aneurysm, congenital of pulmonary artery
78.6
7.4
8
*
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
2.2
7.3
60
272
R55
ICD-10 Finland
Syncope and collapse
1.6
7.3
190
1227
EBA15
NOMESCO Finland
Extraction of multiple teeth
1.9
7.3
88
460
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
13.1
7.3
12
9
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
13.1
7.3
12
9
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
6.3
7.3
18
28
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
7.3
170
1072
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.8
7.3
101
553
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
7.2
129
759
127
Kela drug reimbursment
Transplant complication
2.3
7.2
50
211
AE1
HP
Pulmonary artery thrombendarterectomy
+∞
7.2
7
*
7459X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Unspecified defect of septal closure
+∞
7.2
7
*
FFF20
NOMESCO Finland
Anastomosis to left atrium from partially anomalous pulmonary veins
+∞
7.2
7
*
FFF96
NOMESCO Finland
Other operation for partially anomalous pulmonary veins
+∞
7.2
7
*
KC1JB
NOMESCO Finland
Miktiocystography with X-ray
4.3
7.2
18
41
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
10.6
7.2
13
12
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
3.8
7.2
21
54
3A019, ,
NOMESCO Finland
6.7
7.2
17
25
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.4
7.1
47
194
Q76.30
ICD-10 Finland
Hemivertebra fusion or failure of segmentation with scoliosis
15.4
7.1
11
7
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.1
863
7164
FN1AD
NOMESCO Finland
CT of coronary arteries
2.7
7.1
37
136
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
7.1
132
786
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
7.1
404
3028
5512
FHL
Cleavage or ligation of the ductus arteriosus
29.4
7.1
9
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
2.6
7.1
39
148
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
2.6
7.0
40
154
Z50.0
ICD-10 Finland
Cardiac rehabilitation
4.1
7.0
19
46
H50.0
ICD-10 Finland
Convergent concomitant strabismus
2.7
7.0
37
137
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
7.0
293
2083
SPAT1301
SPAT
No procedures
1.3
7.0
647
5192
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
3.4
7.0
24
69
RL140, ,
NOMESCO Finland
3.1
7.0
28
89
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.0
7.0
69
337
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.3
7.0
51
221
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.7
7.0
135
813
WX870
NOMESCO Finland
Other postsurgical intensive care
5.5
6.9
19
34
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
2.7
6.9
35
127
TKC20
NOMESCO Finland
Catheterisation of bladder
1.8
6.9
103
577
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
6.8
6.9
16
23
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
2.8
6.9
34
122
Z2445
NOMESCO Finland
Psychologist
1.6
6.8
156
979
C08DB01
ATC
diltiazem; oral
2.1
6.8
64
307
Q87.4
ICD-10 Finland
Marfan syndrome
13.5
6.8
11
8
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
7.4
6.8
15
20
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.6
6.8
138
842
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.4
6.8
44
181
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
6.7
121
714
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.7
88
473
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
3.8
6.7
20
52
TJD20
NOMESCO Finland
Change of gastrostomy tube
3.2
6.7
25
76
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
10.7
6.7
12
11
5210A
ICD-9 Finland
Diseases of hard tissues of teeth, Dental caries
10.7
6.7
12
11
FM1CE
NOMESCO Finland
Ultrasound examination of heart through catheter
39.2
6.7
8
*
TFW99
NOMESCO Finland
Other minor procedure in cardiac surgery
39.2
6.7
8
*
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
6.6
6.7
16
24
C02KX04
ATC
macitentan; oral
16.4
6.7
10
6
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.2
6.6
50
220
R01.0
ICD-10 Finland
Benign and innocent cardiac murmurs
2.0
6.6
70
351
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
22.1
6.6
9
*
H50.30
ICD-10 Finland
Intermittent esotropy
2.8
6.6
32
114
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.7
6.5
123
735
N18
ICPC
Paralysis/weakness
2.6
6.5
35
131
742, ,
NOMESCO Finland
12.0
6.5
11
9
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
12.0
6.5
11
9
P29.9
ICD-10 Finland
Cardiovascular disorder originating in the perinatal period, unspecified
12.0
6.5
11
9
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.0
6.5
68
340
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
6.5
170
1102
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.2
6.5
50
222
L04AD02
ATC
tacrolimus; systemic
2.5
6.5
39
155
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
2.6
6.4
35
132
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
2.0
6.4
67
334
ZX120
NOMESCO Finland
Intravenous
1.5
6.4
186
1232
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.4
584
4675
K73
ICPC
Congenital anomaly cardiovascular
68.5
6.4
7
*
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
68.5
6.4
7
*
Q90.1
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
68.5
6.4
7
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
2.7
6.4
32
116
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
6.1
6.3
16
26
J01DB01
ATC
cefalexin; oral
1.3
6.3
1911
17468
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
14.0
6.3
10
7
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.2
310
2272
RK260, ,
NOMESCO Finland
6.4
6.2
15
23
I50
ICD-10 Finland
Heart failure
2.4
6.2
39
158
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
10.8
6.2
11
10
Q24.50
ICD-10 Finland
Congenital coronary artery-coronary fistula
+∞
6.2
6
*
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
6.2
6
*
FFE10
NOMESCO Finland
Creation or expansion of ASD in open heart surgery
+∞
6.2
6
*
7454C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[LEFT VENTRICULAR AND RIGHT ATRIAL COMMUNICATION]
+∞
6.2
6
*
5513
FHL
Coarctation resection, plastic or bypass
+∞
6.2
6
*
AB2
HP
AVR bio, stent
9.1
6.2
12
13
AB4AE
NOMESCO Finland
Spinal ultrasound examination
17.7
6.2
9
5
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
3.2
6.2
24
75
FK1AC
NOMESCO Finland
Right cardioangiography
26.2
6.2
8
*
K04
ICPC
Palpitations/awareness of heart
1.7
6.2
103
597
I45.9
ICD-10 Finland
Conduction disorder, unspecified
3.7
6.1
19
51
J96.1
ICD-10 Finland
Chronic respiratory failure
2.6
6.1
33
124
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.6
6.1
122
741
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
6.1
136
849
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
3.5
6.1
20
56
H52.0
ICD-10 Finland
Hypermetropia
1.9
6.1
69
355
DFF20
NOMESCO Finland
Audiometry for children
2.4
6.1
38
154
A12BA01
ATC
potassium chloride; oral
2.1
6.0
53
248
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.6
6.0
130
805
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
5.2
6.0
17
32
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
6.0
857
7217
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
6.0
126
775
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
6.0
131
814

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1081
4054
3.74
226.09
4.8
3.4
1133.15
1175.45
ng/l
0.13
963
3386
880
2984
3.84
211.91
3.3
3.6
31.12
30.07
s
4.30
865
2915
1529
7429
3.44
207.20
25.9
11.7
1.49
1.19
inr
18.34
429
2210
265
316
9.02
202.87
1.1
1.2
116.71
111.65
%
1.28
258
294
426
993
4.82
167.05
2.9
4.8
21.84
22.09
s
0.36
353
913
231
358
6.83
140.00
1.3
1.3
3.74
5.16
u/ml
0.70
100
170
429
1196
4.00
131.62
4.0
3.7
188.23
182.61
ng/l
0.10
384
1072
1041
5115
2.65
119.81
5.2
5.3
81.37
91.01
%
25.59
1025
5001
935
4742
2.45
96.25
2.4
2.6
—
—
—
0
0
1073
6085
2.23
82.15
2.5
2.7
—
—
—
0
0
944
5092
2.27
81.55
2.7
2.2
226.74
236.54
u/l
0.11
907
4836
1405
9063
2.12
75.17
2.8
2.8
—
—
—
0
0
655
3181
2.35
70.91
4.2
3.5
1171.38
531.64
ng/l
2.14
513
2192
631
3042
2.36
69.28
5.8
6.4
0.83
0.82
mmol/l
1.66
607
2891
87
102
8.60
66.77
1.2
1.2
21.60
10.77
u/ml
—
5
13
92
116
8.01
66.55
1.1
1.1
1.09
1.05
ratio
0.75
27
48
1645
11570
2.05
65.89
7.2
5.6
6.17
6.48
mmol/l
10.10
1567
10778
1007
6024
2.03
62.82
4.3
3.2
43.62
46.25
ng/l
0.09
692
3654
1721
12453
2.03
61.71
4.7
3.3
—
—
—
0
0
73
80
9.16
59.01
1.2
1.3
—
—
—
0
0
256
873
3.07
55.49
4.3
5.7
3.00
3.21
g/l
1.83
248
842
41
19
21.44
53.92
2.4
3.1
—
—
—
0
0
58
56
10.34
51.36
4.7
8.2
—
—
—
0
0
426
1965
2.34
50.29
8.3
11.3
7.09
7.49
mmol/l
0.75
419
1906
55
51
10.76
50.06
3.8
8.0
—
—
—
0
0
1267
8960
1.74
41.34
10.7
8.4
1.21
1.22
mmol/l
4.39
1196
8315
557
3066
1.99
41.02
7.5
8.7
1.19
1.17
mmol/l
0.87
536
2882
741
4559
1.82
38.44
5.0
3.4
—
—
—
0
0
2378
20584
2.42
38.38
20.1
14.1
139.47
139.58
mmol/l
1.64
2352
20036
2379
20635
2.40
37.52
20.1
14.2
3.97
3.95
mmol/l
1.99
2350
20039
278
1246
2.32
34.42
2.2
2.3
14.25
7.10
ug/l
4.14
246
1099
1316
9716
1.65
34.10
10.0
8.6
1.21
1.22
mmol/l
3.36
1102
8500
47
65
7.19
31.36
1.2
1.1
—
—
—
0
0
1378
10518
1.60
29.44
7.0
7.7
—
—
—
0
0
346
1812
2.00
28.55
13.0
9.2
13.38
12.90
kpa
0.77
337
1741
346
1812
2.00
28.55
13.1
9.2
5.30
5.14
kpa
2.08
337
1737
30
26
11.41
28.45
1.0
1.0
—
—
—
0
0
404
2248
1.90
27.84
9.5
8.1
7.41
7.41
ph
0.03
34
156
344
1815
1.98
27.75
13.2
9.2
0.99
0.88
mmol/l
0.22
292
1445
405
2259
1.89
27.70
9.6
8.1
5.17
5.05
kpa
2.71
399
2177
2377
21108
2.10
27.01
16.6
12.5
22.53
22.34
mg/l
0.11
1925
15985
1431
11155
1.56
26.86
6.4
7.2
0.58
0.57
e9/l
1.18
1223
9570
206
902
2.34
26.76
18.3
12.8
—
—
—
0
0
43
65
6.57
26.46
1.2
1.2
—
—
—
0
0
907
6387
1.60
26.44
1.5
1.6
—
—
—
0
0
312
1618
2.01
26.37
14.0
9.9
96.05
95.41
%
0.80
304
1563
1429
11163
1.56
26.36
6.4
7.2
0.04
0.04
e9/l
0.57
1223
9572
419
2408
1.84
25.96
12.4
10.2
—
—
—
0
0
225
1043
2.22
25.51
15.9
11.4
94.66
94.16
%
0.51
225
1038
2413
21643
2.16
25.15
17.8
13.5
71.12
70.80
umol/l
0.20
2413
21637
1456
11505
1.54
24.85
6.4
7.2
1.96
2.09
e9/l
2.82
1264
10124
439
2615
1.77
23.99
3.0
2.8
21.47
22.96
%
1.59
395
2310
656
4357
1.63
23.89
2.7
2.4
1.20
1.20
mg/l
0.01
491
3243
1453
11542
1.52
23.69
6.8
7.6
0.19
0.20
e9/l
1.32
1258
10064
335
1852
1.88
23.32
9.7
8.4
—
—
—
0
0
123
450
2.76
23.24
5.3
10.9
—
—
—
0
0
1233
9493
1.51
23.10
7.2
6.6
16.26
13.75
umol/l
2.54
1145
8963
1317
10303
1.50
22.70
6.8
7.4
0.66
0.66
%
0.15
1262
9741
1355
10667
1.50
22.63
6.9
7.6
8.62
8.38
%
2.22
1302
10108
1301
10188
1.50
22.08
10.4
9.9
0.00
0.00
e9/l
0.47
1043
8174
1344
10599
1.49
22.00
6.7
7.4
2.90
2.97
%
0.60
1290
10031
2421
21912
2.08
21.83
16.4
11.1
—
—
—
0
0
455
2811
1.71
21.66
2.9
2.7
2.45
2.42
g/l
0.74
424
2622
1038
7822
1.49
20.91
5.7
5.7
36.25
36.42
g/l
0.40
969
7331
485
3081
1.66
20.71
3.0
2.7
12.67
13.65
umol/l
2.36
453
2902
277
1495
1.91
20.66
12.7
9.7
122.46
122.78
g/l
0.09
270
1458
1382
11051
1.47
20.50
6.7
7.3
29.35
31.05
%
6.45
1328
10504
251
1337
1.93
19.44
3.7
4.1
1.22
1.23
mmol/l
1.01
236
1162
41
83
4.90
18.65
3.2
3.9
4.77
3.69
%
—
10
40
660
4618
1.53
18.48
4.1
4.3
—
—
—
0
0
102
382
2.68
18.46
5.4
5.3
1.96
2.39
mmol/l
1.02
65
236
1352
10894
1.44
18.45
6.5
7.1
55.46
54.05
%
4.06
1301
10349
31
49
6.25
18.30
5.5
12.5
—
—
—
0
0
726
5200
1.51
18.15
4.0
3.9
7.40
7.40
ph
0.93
214
954
421
2678
1.64
17.65
6.4
7.9
7.39
7.37
ph
—
9
13
68
213
3.18
16.98
5.2
18.7
11.93
10.99
%
1.99
68
213
1515
12571
1.43
16.94
8.6
9.8
3.93
3.90
e9/l
0.23
1312
10845
711
5137
1.49
16.81
2.7
2.5
3.16
2.80
mg/l
2.42
627
4451
28
44
6.28
16.62
1.5
1.2
—
—
—
0
0
1734
14782
1.44
16.44
4.4
4.1
9.47
10.21
mm/h
1.77
1633
13782
409
2655
1.60
15.65
6.2
7.8
5.92
5.80
kpa
1.75
401
2590
407
2644
1.60
15.52
6.3
7.8
1.40
1.45
mmol/l
0.11
343
2131
1693
14480
1.41
14.94
7.8
7.0
88.56
87.50
u/l
0.27
1601
13663
109
467
2.34
14.90
5.4
4.8
7.42
7.41
ph
0.30
102
410
319
1982
1.65
14.51
5.8
8.5
23.79
23.66
mmol/l
0.36
319
1966
369
2381
1.60
14.41
6.1
7.7
5.26
4.95
kpa
1.51
363
2319
97
402
2.41
14.29
4.2
4.4
—
—
—
0
0
63
218
2.87
13.31
2.7
3.1
0.81
0.82
nmol/l
0.05
48
171
91
379
2.40
13.28
2.8
2.8
17.16
16.84
%
0.32
51
215
2137
19217
1.48
13.16
19.8
15.5
14.48
14.27
%
1.11
2115
18882
162
869
1.88
12.26
4.8
7.1
1.24
1.24
%
0.02
162
863
75
298
2.51
12.14
2.3
2.2
1.81
1.72
mmol/l
0.27
75
292
140
724
1.94
11.83
1.8
2.0
1.27
1.43
g/l
1.35
116
633
173
965
1.81
11.56
6.4
5.9
—
—
—
0
0
1600
13836
1.34
11.41
4.5
4.2
—
—
—
0
0
1190
9864
1.33
11.36
3.5
3.0
96.17
96.14
ug/l
0.00
1106
9246
343
2325
1.51
10.61
3.6
4.4
1.78
1.63
%
1.49
311
2133
305
2026
1.54
10.36
3.0
3.1
0.21
0.21
g/l
1.40
298
1920
228
1427
1.62
10.01
4.2
4.8
0.06
0.52
%
0.89
65
394
374
2613
1.47
9.93
2.4
2.0
—
—
—
0
0
237
1504
1.60
9.83
4.3
4.7
0.14
0.11
%
0.24
74
473
38
118
3.18
9.74
1.8
1.4
—
—
—
0
0
229
1445
1.60
9.72
4.0
4.3
0.75
0.64
%
0.38
75
482
246
1583
1.57
9.61
4.3
4.6
1.08
0.90
%
0.43
84
553
729
5732
1.34
9.60
3.5
3.5
0.44
0.37
e6/l
0.29
576
4302
1511
13128
1.30
9.51
4.6
4.2
425.67
1882.33
e6/l
1.48
24
163
559
4224
1.38
9.51
3.2
2.9
5.26
6.48
e6/l
1.43
507
3780
258
1697
1.54
9.15
4.0
3.7
—
—
—
0
0
79
368
2.14
8.95
4.1
4.9
—
—
—
0
0
40
135
2.93
8.94
2.0
1.4
1673.12
2083.84
e6/l
0.26
32
94
2523
23903
1.90
8.87
25.9
18.5
39.82
40.35
%
1.66
2428
22667
2078
18946
1.36
8.81
5.2
4.5
1.95
2.02
mu/l
0.36
1940
17666
760
6076
1.32
8.77
3.0
3.2
2.36
2.36
mmol/l
0.31
671
5440
2524
23932
1.89
8.59
24.8
18.2
89.53
89.37
fl
0.80
2506
23613
2524
23933
1.88
8.57
24.7
18.1
29.88
29.88
pg
0.00
2506
23616
2524
23937
1.88
8.51
24.8
18.2
4.51
4.55
e12/l
3.70
2468
23140
37
123
2.97
8.50
1.9
1.4
70402.27
28731.71
e6/l
0.61
26
72
2522
23918
1.86
8.41
24.9
18.3
248.93
259.45
e9/l
12.87
2472
23181
2524
23943
1.87
8.41
24.8
18.2
6.83
6.80
e9/l
0.23
2471
23151
64
281
2.26
8.40
7.7
8.1
12.02
10.74
mg/l
0.86
55
263
2524
23946
1.87
8.36
25.4
18.4
133.81
135.31
g/l
5.49
2508
23635
821
6668
1.30
8.35
4.0
3.7
33.30
31.77
u/l
0.27
781
6359
204
1302
1.58
8.27
2.2
2.9
65.50
66.50
g/l
0.92
187
1208
770
6209
1.30
8.25
3.9
3.6
156.13
61.52
e6/l
0.36
610
4726
40
144
2.75
7.98
1.8
1.4
31.35
32.33
g/l
0.21
35
126
736
5925
1.30
7.92
6.2
7.7
—
—
—
0
0
203
1307
1.56
7.92
3.8
3.4
4.72
4.70
pmol/l
0.08
184
1173
711
5698
1.30
7.92
3.4
3.4
—
—
—
0
0
525
4046
1.34
7.70
3.4
3.0
548.99
554.26
mosm/kgh2o
0.20
474
3490
102
550
1.85
7.69
1.1
1.3
—
7.52
—
0
9
709
5712
1.29
7.53
2.7
2.7
59.90
72.43
u/l
0.43
644
5305
155
948
1.64
7.50
9.6
7.8
24.70
24.43
mmol/l
0.44
147
904
86
443
1.93
7.46
2.5
2.4
134.79
131.58
g/l
0.61
67
344
247
1682
1.48
7.43
3.5
3.7
75.20
69.03
e9/l
1.44
172
1184
110
616
1.78
7.35
3.5
2.4
676.98
393.27
ug/l
0.58
104
571
1795
16198
1.27
7.16
4.4
3.9
14.73
14.58
pmol/l
1.79
1655
14879
886
7388
1.26
7.03
4.4
4.1
59.13
75.36
e6/l
0.56
646
5053
331
2406
1.40
6.99
4.6
4.3
8.26
7.15
umol/l
0.52
290
2044
369
2734
1.37
6.94
1.8
1.7
1241.56
1178.89
nmol/l
0.60
273
2094
80
416
1.91
6.78
3.7
4.1
54.89
55.18
%
0.07
80
416
48
209
2.27
6.50
2.4
2.2
31.35
32.63
pg
0.92
48
209
91
504
1.79
6.35
8.3
7.9
1.19
1.24
mmol/l
0.24
82
442
52
240
2.14
6.14
3.1
5.1
5.86
6.67
mmol/l
2.01
45
206
42
178
2.33
6.07
3.5
4.6
—
—
—
0
0
308
2264
1.38
6.07
1.7
1.5
—
—
—
0
0
24
76
3.11
6.05
1.5
1.9
—
—
—
0
0
76
406
1.86
5.98
3.4
3.7
3.97
3.94
e9/l
0.04
76
406
381
2909
1.33
5.86
1.4
1.4
516.67
521.05
titre
0.02
72
571
630
5143
1.26
5.79
4.1
3.7
0.01
0.00
estimate
0.21
248
1792
103
611
1.68
5.68
2.8
3.4
—
—
—
0
0
1825
16687
1.23
5.53
5.0
4.9
37.91
38.77
mmol/mol
4.26
1715
15651
29
110
2.60
5.33
2.0
1.4
—
—
—
0
0
14
25
5.50
5.27
1.1
1.2
—
—
—
0
0
37
160
2.28
5.16
40.8
41.5
6.99
6.83
ug/l
0.20
37
146
220
1573
1.40
5.13
5.6
5.7
73.08
72.47
ng/l
0.05
191
1447
118
746
1.57
5.08
1.2
1.2
3.50
0.99
u/ml
—
5
60
145
962
1.50
5.02
1.7
2.4
—
—
—
0
0
15
31
4.76
5.01
7.5
11.2
—
—
—
0
0
32
133
2.37
4.89
4.5
6.3
125.83
72.04
mg/l
1.28
24
118
475
3821
1.26
4.88
1.5
1.5
19.88
20.53
nmol/l
0.47
403
3301
40
184
2.15
4.83
2.3
3.2
—
—
—
0
0
2301
21705
1.31
4.77
11.4
9.7
26.02
26.50
u/l
0.55
2243
21012
29
118
2.42
4.65
2.0
1.6
—
—
—
0
0
43
207
2.05
4.64
2.3
2.1
—
—
—
0
0
1489
13458
1.19
4.62
3.7
3.4
44.30
42.34
u/l
0.48
1419
12744
115
744
1.54
4.51
1.4
1.6
1.14
1.17
g/l
0.51
109
708
323
2500
1.30
4.49
2.0
1.7
—
—
—
0
0
89
544
1.62
4.45
1.4
2.9
—
—
—
0
0
62
344
1.78
4.41
10.2
9.8
10.51
11.41
mmol/l
1.27
55
311
62
345
1.78
4.37
10.2
9.8
106.44
105.35
mmol/l
1.45
55
312
12
23
5.12
4.37
1.2
1.2
—
—
—
0
0
101
644
1.56
4.24
5.4
5.2
—
—
—
0
0
60
334
1.78
4.23
5.2
4.2
—
—
—
0
0
293
2257
1.30
4.23
1.2
1.2
—
—
—
0
0
88
544
1.60
4.22
2.5
2.0
3.41
4.86
iu/l
1.41
29
203
584
4879
1.22
4.20
1.6
1.7
1.31
1.37
mmol/l
1.02
482
4228
18
62
2.85
4.00
1.1
1.2
—
—
—
0
0
366
2928
1.26
3.91
2.4
2.7
2.43
2.44
mmol/l
1.32
314
2550
312
2449
1.28
3.90
1.2
1.2
—
—
—
0
0
1116
9935
1.17
3.88
3.7
3.5
0.01
0.00
estimate
0.37
260
1911
240
1825
1.32
3.82
1.2
1.4
184.20
276.67
u/ml
1.40
226
1707
653
5562
1.20
3.80
3.0
2.8
—
—
—
0
0
926
8138
1.18
3.74
3.2
3.2
6.02
6.00
ph
0.06
79
782
107
720
1.47
3.55
1.4
1.6
0.22
0.22
g/l
0.01
102
686
70
430
1.61
3.50
1.4
2.3
38.12
38.41
g/l
0.13
59
388
24
103
2.29
3.49
1.1
1.1
1169.63
1681.70
miu/ml
2.02
24
103
80
508
1.56
3.48
1.7
2.3
10.51
10.26
g/l
0.17
69
465
44
238
1.82
3.47
3.4
4.0
—
—
—
0
0
94
620
1.50
3.45
8.3
6.8
1.81
1.59
%
1.59
87
581
1108
9929
1.16
3.40
5.0
4.8
0.00
0.00
estimate
0.50
259
1854
1116
10008
1.16
3.39
3.8
3.5
0.01
0.00
estimate
0.27
250
1801
93
615
1.50
3.37
8.6
6.9
0.94
0.90
%
0.51
86
577
782
6831
1.17
3.33
2.0
1.9
97.10
96.44
pmol/l
0.15
446
3634
178
2261
0.75
3.30
1.3
1.3
—
—
—
0
0
252
1971
1.28
3.27
4.5
4.0
34.67
32.04
%
3.38
194
1419
56
332
1.66
3.24
2.0
2.2
72.90
72.23
mmol/l
0.04
48
286
524
4438
1.19
3.21
3.5
3.0
3677.25
5051.79
umol/l
0.30
466
3978
125
885
1.40
3.19
4.8
5.6
0.31
0.36
g/l
0.26
85
512
91
609
1.48
3.14
2.4
2.1
2.71
1.71
ug/l
0.37
79
539
88
589
1.48
3.04
1.3
2.6
3.61
3.56
mmol/l
0.19
80
561
41
228
1.77
2.99
1.7
3.8
—
—
—
0
0
191
1463
1.30
2.93
2.2
2.3
18.59
22.29
au/ml
0.23
11
112
43
245
1.73
2.90
1.4
1.5
62.47
98.78
mu/l
0.38
38
218
20
87
2.26
2.86
1.1
1.4
176.25
167.14
mmol/24h
0.24
20
87
35
192
1.79
2.70
1.3
1.3
—
—
—
0
0
1964
18489
1.16
2.70
4.5
3.9
4.37
4.66
mmol/l
32.73
1866
17430
28
143
1.93
2.68
1.7
1.6
25.06
35.72
%
0.78
17
99
175
1343
1.29
2.67
2.0
2.3
8656.66
6523.01
u/l
0.32
57
492
202
1579
1.27
2.67
4.5
4.2
—
—
—
0
0
237
1889
1.25
2.66
2.9
3.3
10.00
9.93
g/l
0.09
227
1768
6
10
5.88
2.65
1.0
1.0
40.20
35.94
s
—
6
10
1879
17660
1.15
2.54
4.2
3.6
1.19
1.27
mmol/l
7.49
1762
16494
419
3551
1.18
2.54
2.8
3.0
0.98
1.00
e6/l
0.04
242
1999
17
73
2.29
2.52
1.5
1.4
3.33
4.20
%
—
6
15
24
119
1.98
2.51
5.6
4.0
—
—
—
0
0
8
20
3.92
2.51
1.1
1.5
57.00
90.60
ng/l
—
8
20
1948
18360
1.15
2.51
4.5
3.9
1.42
1.45
mmol/l
3.20
1840
17211
50
310
1.59
2.50
2.0
1.6
—
—
—
0
0
45
272
1.63
2.49
1.1
1.3
—
—
—
0
0
85
591
1.42
2.47
1.4
2.8
5.85
24.46
e6/l
1.01
67
448
62
405
1.51
2.47
1.2
1.2
—
—
—
0
0
85
592
1.42
2.45
1.4
2.8
214.65
884.72
e6/l
1.43
69
468
7
16
4.29
2.42
2.4
2.1
—
—
—
0
0
172
1338
1.28
2.39
1.3
1.3
27.65
50.34
au/ml
—
8
62
47
291
1.59
2.37
3.4
3.8
1.10
1.30
%
0.24
41
266
615
5399
1.15
2.37
3.7
3.1
—
—
—
0
0
1977
18682
1.15
2.34
4.9
4.3
2.59
2.79
mmol/l
20.89
1864
17499
36
209
1.70
2.33
1.1
1.1
—
—
—
0
0
104
759
1.36
2.29
1.3
1.3
—
—
—
0
0
76
530
1.42
2.21
1.2
1.2
6.14
11.54
u/ml
0.62
16
83
210
1691
1.23
2.19
1.3
1.2
142.52
152.83
iu/ml
0.15
82
589
6
14
4.20
2.11
2.2
1.2
—
—
—
0
0
9
30
2.94
2.09
2.1
1.8
—
—
—
0
0
176
1400
1.25
2.07
3.0
4.2
4.87
26.05
ug/l
2.24
138
1108
172
1365
1.25
2.06
3.4
3.4
—
—
—
0
0
801
7213
1.13
2.05
2.0
2.0
—
—
—
0
0
164
1295
1.26
2.05
1.5
1.4
—
—
—
0
0
1902
17981
1.13
2.05
4.3
3.9
5.71
5.78
mmol/l
1.56
1744
16594
33
195
1.66
2.04
1.7
1.7
59.17
56.41
%
0.17
24
133
74
524
1.39
2.00
1.2
1.2
2.14
4.38
u/ml
—
9
50
237
1957
1.20
1.95
1.4
1.3
—
—
—
0
0
395
3409
1.16
1.92
3.2
3.2
2.88
2.65
e6/l
0.17
215
1864
70
496
1.39
1.90
2.8
2.5
—
—
—
0
0
9
33
2.67
1.88
1.4
1.6
—
—
—
0
0
34
518
0.64
1.87
1.0
1.1
1.95
0.32
u/ml
0.39
13
219
52
350
1.46
1.86
2.6
4.3
6.73
59.61
u/ml
0.87
52
345
106
805
1.30
1.84
1.3
1.2
—
—
—
0
0
7
22
3.12
1.83
2.9
4.2
4.34
4.55
mmol/l
—
7
22
89
664
1.32
1.76
2.0
1.9
—
—
—
0
0
29
450
0.63
1.75
1.1
1.2
53.00
1153.98
iu/ml
—
9
127
12
53
2.22
1.72
1.1
1.5
—
—
—
0
0
68
490
1.37
1.70
4.4
3.7
13.22
8.80
umol/l
0.55
53
392
14
67
2.05
1.67
1.1
1.4
82.70
92.74
nmol/24h
0.26
14
67
29
176
1.62
1.66
31.9
34.8
129.92
141.99
ug/l
0.32
24
161
918
8414
1.10
1.65
3.0
2.6
75.74
74.05
nmol/l
1.06
830
7758
45
303
1.46
1.64
1.2
1.3
—
—
—
0
0
26
154
1.66
1.64
1.5
1.4
62764.76
126177.23
e6/l
0.36
21
111
384
3349
1.14
1.63
1.3
1.3
16.30
27.42
iu/ml
4.85
107
1008
22
357
0.60
1.62
1.2
1.4
5.47
13.22
u/ml
0.61
12
208
14
68
2.02
1.61
1.1
1.5
—
—
—
0
0
8
31
2.53
1.61
2.3
1.6
39.05
23.81
g/l
—
8
22
33
211
1.54
1.54
1.1
1.2
24.93
36.72
mg/l
2.63
28
169
19
105
1.78
1.53
1.7
5.0
207.17
169.50
umol/l
—
6
62
14
70
1.96
1.50
2.0
2.2
—
—
—
0
0
389
3419
1.13
1.48
1.6
1.6
456.82
37710984.73
pmol/l
3.51
306
2909
146
1188
1.21
1.46
1.2
1.2
—
—
—
0
0
49
345
1.40
1.44
3.2
3.2
1.25
1.46
e9/l
1.19
40
283
5
16
3.06
1.40
1.2
1.1
2.10
1.92
mmol/l
—
5
9
27
169
1.57
1.40
1.4
2.0
—
—
—
0
0
28
177
1.55
1.40
1.6
1.7
—
—
—
0
0
46
323
1.40
1.38
2.5
2.5
—
—
—
0
0
17
94
1.77
1.38
1.4
1.2
—
—
—
0
0
35
234
1.47
1.36
1.4
1.5
318.83
410.16
pmol/l
0.68
29
204
37
251
1.45
1.34
4.8
3.4
1.62
1.70
umol/l
0.41
37
245
42
292
1.41
1.34
2.9
4.0
—
—
—
0
0
473
4233
1.11
1.34
4.5
4.4
1.67
2.37
ug/l
2.08
403
3833
24
148
1.59
1.33
1.2
1.1
—
—
—
0
0
103
1233
0.81
1.31
2.5
2.6
—
—
—
0
0
9
42
2.10
1.30
1.3
1.1
—
—
—
0
0
82
636
1.27
1.29
1.9
1.9
113.85
101.01
u/ml
0.65
20
79
44
312
1.39
1.27
1.4
1.4
—
—
—
0
0
14
75
1.83
1.26
1.4
1.2
—
—
—
0
0
67
508
1.30
1.26
5.1
3.8
25.63
22.20
nmol/l
0.97
67
493
14
76
1.81
1.22
1.7
1.3
—
—
—
0
0
14
76
1.81
1.22
1.7
1.3
—
—
—
0
0
14
76
1.81
1.22
1.7
1.3
—
—
—
0
0
77
599
1.27
1.20
1.5
1.4
292.13
315.31
ug/g
0.45
40
331
69
854
0.79
1.20
1.1
1.2
3.53
3.02
u/ml
0.16
46
569
41
545
0.73
1.19
3.4
2.2
0.87
0.73
nmol/l
0.61
35
462
168
1419
1.17
1.16
2.5
2.6
4.88
5.41
e9/l
0.27
139
1224
752
6931
1.09
1.15
2.7
2.5
—
—
—
0
0
0
35
0.00
1.14
0.0
1.2
—
—
—
0
0
256
2237
1.13
1.11
2.8
2.4
352.29
357.27
nmol/l
0.13
240
2088
47
602
0.76
1.08
1.1
1.1
6.65
6.00
u/ml
0.11
29
344
13
72
1.77
1.08
1.4
2.9
—
—
—
0
0
127
1456
0.85
1.07
1.7
1.9
—
—
—
0
0
22
142
1.52
1.05
1.2
1.2
—
—
—
0
0
33
443
0.73
1.04
1.1
1.1
1.31
4.09
u/ml
2.10
17
178
8
148
0.53
1.03
1.3
1.6
—
—
—
0
0
214
1861
1.14
1.02
2.4
2.4
42.68
64.31
u/l
0.37
189
1564
44
562
0.76
1.01
1.0
1.1
9.14
8.49
u/ml
0.08
26
290
53
404
1.29
1.00
2.1
1.7
10747.34
13012.08
e6/l
0.27
41
302
9
47
1.88
1.00
4.8
2.1
—
—
—
0
0
20
291
0.67
0.99
1.1
1.2
0.59
2.30
u/ml
0.93
13
163
15
90
1.63
0.97
4.4
3.2
67.21
115.65
ug/l
1.18
15
90
15
90
1.63
0.97
2.5
2.5
2212.67
2079.00
ml
0.26
15
81
59
459
1.26
0.96
1.1
1.2
30.67
43.64
u/ml
—
6
37
496
4529
1.09
0.95
3.6
3.3
465.33
335.90
mg/l
0.23
324
3007
94
775
1.19
0.91
1.6
1.7
295.94
213.31
u/ml
1.58
54
409
18
116
1.52
0.89
3.1
2.2
610.15
628.46
ml
0.09
13
79
13
77
1.66
0.89
1.6
2.5
13.72
18.25
umol/l
1.50
13
77
44
334
1.29
0.88
2.0
1.6
—
—
—
0
0
6
29
2.03
0.87
1.0
1.1
—
—
—
0
0
6
29
2.03
0.87
1.0
1.1
—
—
—
0
0
6
29
2.03
0.87
1.0
1.1
—
—
—
0
0
74
871
0.83
0.87
1.0
1.2
1.40
1.14
u/ml
0.18
41
541
76
892
0.83
0.87
1.0
1.2
7.02
5.78
u/ml
0.26
47
607
26
182
1.40
0.87
1.5
1.6
—
—
—
0
0
10
55
1.78
0.86
1.2
1.2
—
—
—
0
0
122
1372
0.86
0.85
1.8
2.0
—
—
—
0
0
68
548
1.22
0.84
2.7
3.5
18.75
2664.37
u/ml
0.81
63
462
10
56
1.75
0.82
1.3
2.2
—
—
—
0
0
82
678
1.19
0.79
1.1
1.2
—
—
—
0
0
12
72
1.63
0.79
2.7
2.5
—
—
—
0
0
132
1467
0.87
0.79
1.7
2.0
—
—
—
0
0
40
306
1.28
0.78
1.3
1.8
—
1217.78
—
0
9
17
241
0.69
0.78
1.4
1.6
7.78
7.67
mmol/l
0.08
17
233
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
45
350
1.26
0.77
1.7
3.8
—
—
—
0
0
39
299
1.28
0.75
3.5
3.3
0.34
0.20
e9/l
1.58
30
237
134
1481
0.88
0.75
1.8
2.0
—
—
—
0
0
88
1002
0.85
0.74
1.5
1.4
—
—
—
0
0
48
379
1.24
0.74
1.1
1.1
—
—
—
0
0
58
468
1.22
0.73
1.8
1.7
—
—
—
0
0
83
948
0.85
0.73
1.1
1.1
—
—
—
0
0
179
1579
1.12
0.73
2.4
2.2
11.64
11.69
nmol/l
0.03
160
1417
134
1477
0.88
0.72
1.7
2.0
—
—
—
0
0
15
98
1.50
0.72
2.7
3.2
8.83
10.64
mg/l
—
10
81
20
139
1.41
0.72
2.1
2.2
—
—
—
0
0
54
640
0.82
0.72
1.5
1.5
—
—
—
0
0
19
131
1.42
0.71
1.0
1.1
—
—
—
0
0
39
302
1.27
0.71
3.5
3.3
463.43
575.65
e6/l
1.09
30
236
17
115
1.45
0.70
1.1
1.2
316.65
203.40
iu/ml
0.68
17
115
5
26
1.88
0.69
1.2
1.4
—
—
—
0
0
19
132
1.41
0.69
1.0
1.0
—
—
—
0
0
53
626
0.83
0.69
1.5
1.5
—
—
—
0
0
13
188
0.68
0.68
1.2
1.3
3.82
10.90
u/ml
0.66
13
177
23
166
1.36
0.68
3.6
3.3
56.61
53.00
%
0.31
18
148
510
4733
1.07
0.66
4.1
3.9
46.34
9.46
mg/mmol
0.56
328
3092
53
623
0.83
0.66
1.4
1.5
—
—
—
0
0
346
3168
1.08
0.66
1.3
1.2
7.73
10.91
u/ml
0.41
124
1204
66
548
1.18
0.64
1.2
1.2
—
—
—
0
0
27
202
1.31
0.64
2.1
2.0
15.95
20.01
umol/l
0.64
22
194
97
831
1.15
0.64
1.0
1.1
—
—
—
0
0
15
102
1.44
0.61
1.2
1.4
—
—
—
0
0
18
127
1.39
0.61
1.1
1.2
—
—
—
0
0
33
256
1.26
0.61
2.2
1.3
0.60
0.59
nmol/l
0.03
33
244
0
20
0.00
0.60
0.0
4.5
—
138.54
—
0
13
8
50
1.57
0.60
1.1
1.2
—
—
—
0
0
39
311
1.23
0.58
1.1
1.2
—
—
—
0
0
17
120
1.39
0.58
2.5
3.1
838.59
1248.17
u/ml
0.65
17
120
85
728
1.15
0.58
1.2
1.2
—
—
—
0
0
295
3083
0.93
0.58
1.7
1.8
—
—
—
0
0
27
206
1.29
0.57
1.5
1.2
—
—
—
0
0
16
112
1.40
0.57
1.0
1.2
—
—
—
0
0
65
546
1.17
0.57
1.3
1.2
—
—
—
0
0
39
312
1.23
0.57
1.7
2.9
—
—
—
0
0
43
506
0.83
0.57
3.0
2.2
—
—
—
0
0
36
287
1.23
0.55
1.2
1.7
—
—
—
0
0
41
332
1.21
0.54
1.6
1.4
18.19
19.66
u/l
0.13
32
285
207
2187
0.92
0.54
1.7
1.8
—
—
—
0
0
595
5587
1.05
0.54
1.5
1.6
2.02
2.03
g/l
0.05
367
3178
86
951
0.88
0.53
1.1
1.2
5.05
2.99
u/ml
0.42
53
619
352
3257
1.07
0.53
2.5
2.7
142.55
107.06
ug/g
0.55
275
2606
30
363
0.81
0.52
1.3
1.3
1.62
3.50
u/ml
0.98
24
231
13
177
0.72
0.52
1.0
1.0
—
—
—
0
0
659
6211
1.05
0.52
1.4
1.5
0.92
2.34
u/ml
6.78
173
1430
23
175
1.29
0.51
3.9
2.4
—
—
—
0
0
148
1324
1.10
0.51
1.6
1.6
—
—
—
0
0
516
4836
1.06
0.51
3.4
3.4
—
—
—
0
0
13
90
1.42
0.50
1.6
2.1
—
—
—
0
0
19
141
1.32
0.50
2.5
2.6
38.62
43.71
%
0.86
13
67
49
408
1.18
0.50
2.7
3.6
36.90
39.03
mg/l
0.08
36
330
102
897
1.12
0.49
4.8
3.1
0.11
0.20
e6/l
1.72
102
869
7
106
0.65
0.48
1.1
1.1
—
—
—
0
0
77
849
0.88
0.47
4.0
3.0
—
—
—
0
0
22
272
0.79
0.47
1.4
2.0
—
—
—
0
0
18
134
1.32
0.47
1.2
1.1
—
—
—
0
0
7
47
1.46
0.46
3.6
2.1
—
—
—
0
0
91
991
0.90
0.46
2.3
2.8
—
—
—
0
0
17
126
1.32
0.46
2.4
2.4
2.64
2.34
u/field
0.08
11
68
12
84
1.40
0.44
1.2
1.4
—
—
—
0
0
109
1172
0.91
0.44
1.9
2.0
—
—
—
0
0
232
2415
0.93
0.44
1.2
1.2
—
—
—
0
0
11
76
1.42
0.43
1.0
1.0
—
—
—
0
0
6
90
0.65
0.42
1.0
1.2
—
—
—
0
0
16
202
0.77
0.42
1.3
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
1989
19266
1.04
0.41
20.4
16.0
333.70
333.53
g/l
0.37
1983
19109
48
408
1.15
0.40
2.6
3.6
50.83
63.31
mg/l
0.31
35
329
149
1353
1.08
0.40
2.0
1.6
19.87
21.47
iu/l
0.26
118
1035
15
112
1.31
0.39
1.1
1.1
—
—
—
0
0
15
112
1.31
0.39
1.1
1.2
—
—
—
0
0
0
18
0.00
0.39
0.0
4.9
—
—
—
0
0
5
34
1.44
0.39
2.8
2.0
—
—
—
0
0
13
95
1.34
0.39
1.0
1.0
27.82
19.48
u/ml
—
5
61
21
253
0.81
0.38
1.6
1.5
—
—
—
0
0
116
1046
1.09
0.37
2.2
1.8
7.61
7.70
u/l
0.03
79
739
98
877
1.10
0.37
1.4
1.3
201.91
230.45
miu/ml
0.35
40
428
100
896
1.10
0.37
2.4
2.4
—
—
—
0
0
37
312
1.16
0.36
1.0
1.0
—
—
—
0
0
37
312
1.16
0.36
1.0
1.0
-2.19
-2.43
mmol/l
0.10
11
72
609
5786
1.04
0.35
3.7
3.6
7.60
7.83
mmol/l
0.55
525
5070
42
470
0.87
0.35
1.4
1.2
—
—
—
0
0
11
80
1.35
0.34
1.4
1.7
—
—
—
0
0
34
385
0.86
0.34
1.4
1.3
—
—
—
0
0
6
85
0.69
0.33
1.2
2.6
—
—
—
0
0
194
1798
1.06
0.32
1.5
1.4
—
—
—
0
0
27
224
1.18
0.32
1.1
1.1
—
—
—
0
0
15
183
0.80
0.32
1.2
1.2
—
—
—
0
0
18
143
1.23
0.32
1.4
1.4
0.93
0.96
g/l
0.14
18
143
35
298
1.15
0.31
2.9
3.9
—
—
—
0
0
309
2905
1.05
0.30
1.6
1.6
—
—
—
0
0
24
277
0.85
0.30
1.5
1.8
—
—
—
0
0
384
3629
1.04
0.30
1.6
1.6
—
—
—
0
0
11
82
1.31
0.30
2.0
1.6
25.00
17.10
nmol/l
—
6
23
28
236
1.16
0.28
2.3
1.3
—
—
—
0
0
63
676
0.91
0.28
2.1
2.5
—
—
—
0
0
107
1121
0.93
0.28
1.7
1.6
381.68
316.55
mu/l
0.94
100
1014
37
320
1.13
0.27
1.0
1.0
19.31
19.53
mmol/l
0.18
37
308
10
126
0.78
0.27
1.0
1.1
—
—
—
0
0
43
377
1.12
0.26
1.0
1.1
—
—
—
0
0
545
5207
1.03
0.25
1.9
2.0
—
—
—
0
0
37
323
1.12
0.25
1.1
1.1
7.38
7.59
iu/ml
—
9
59
17
139
1.20
0.24
2.3
2.1
—
—
—
0
0
16
130
1.21
0.24
1.1
1.3
82.44
75.19
umol/l
0.70
16
130
15
121
1.21
0.24
1.2
1.3
1.45
1.54
g/l
0.86
15
121
134
1383
0.95
0.24
1.4
1.4
—
—
—
0
0
6
83
0.71
0.24
1.7
2.3
157.33
147.79
nmol/l
—
6
73
5
37
1.32
0.23
1.0
1.0
—
—
—
0
0
29
319
0.89
0.22
1.5
1.9
3.79
5.14
mmol/24h
1.24
23
284
13
153
0.83
0.21
12.5
14.3
876.08
816.49
nmol/l
0.17
13
148
32
280
1.12
0.21
1.2
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
113
1166
0.95
0.21
1.7
1.6
—
—
—
0
0
5
42
1.17
0.21
1.2
1.2
—
—
—
0
0
264
2501
1.04
0.21
2.9
2.8
0.78
0.71
ug/l
0.27
160
1493
19
160
1.16
0.21
1.0
1.1
—
—
—
0
0
436
4167
1.03
0.20
1.7
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
2.57
—
0
14
21
180
1.14
0.19
2.4
2.0
—
—
—
0
0
10
80
1.22
0.17
5.8
2.7
—
—
—
0
0
7
61
1.12
0.17
2.7
2.6
—
—
—
0
0
38
404
0.92
0.17
1.9
1.9
—
4.17
—
0
6
11
128
0.84
0.16
1.0
1.2
—
—
—
0
0
5
69
0.71
0.16
1.0
1.4
—
—
—
0
0
8
67
1.17
0.16
1.3
1.2
—
—
—
0
0
12
99
1.19
0.16
1.5
1.4
131.00
140.65
nmol/l
0.27
12
99
438
4367
0.98
0.15
4.0
3.6
1.02
1.02
kg/l
0.41
58
710
139
1312
1.04
0.15
1.2
1.2
—
—
—
0
0
19
165
1.13
0.15
2.5
2.6
2.08
1.50
g/24h
—
7
91
74
762
0.95
0.15
1.6
1.7
—
—
—
0
0
33
350
0.92
0.14
1.1
1.2
—
—
—
0
0
10
82
1.19
0.14
1.2
1.5
—
—
—
0
0
70
720
0.95
0.13
1.1
1.1
0.56
7.56
u/ml
2.65
11
98
48
441
1.07
0.13
1.1
1.1
—
—
—
0
0
25
223
1.10
0.13
2.3
1.3
—
—
nmol/l
—
0
0
27
242
1.09
0.13
2.9
3.6
410.00
368.14
e6/l
0.16
17
161
62
576
1.05
0.13
1.5
1.5
64.29
81.53
titre
—
7
59
9
105
0.84
0.13
3.6
2.7
—
—
—
0
0
23
247
0.91
0.13
1.2
1.2
5.44
16.26
u/ml
0.53
16
194
161
1530
1.03
0.13
1.6
1.5
—
—
—
0
0
19
204
0.91
0.10
1.3
1.4
—
—
—
0
0
21
224
0.92
0.10
3.4
4.0
55.30
95.14
u/ml
—
6
60
13
143
0.89
0.10
4.2
3.2
58.17
144.19
umol/l
—
6
38
15
163
0.90
0.10
1.1
1.0
—
—
—
0
0
5
43
1.14
0.10
1.2
1.1
0.83
3.84
u/ml
—
5
30
5
46
1.06
0.09
1.2
1.4
—
—
—
0
0
54
552
0.96
0.09
11.2
9.0
—
—
—
0
0
15
162
0.91
0.09
1.6
1.3
157.13
225.29
pmol/l
0.57
15
162
90
854
1.03
0.09
1.7
1.7
—
—
—
0
0
21
190
1.08
0.08
1.3
1.7
—
—
—
0
0
5
60
0.82
0.08
2.0
1.8
—
—
—
0
0
18
162
1.09
0.08
2.9
2.7
—
—
—
0
0
11
96
1.12
0.07
1.0
1.2
—
5.17
—
0
6
40
374
1.05
0.07
2.7
2.4
137.18
121.07
ug/min
0.08
22
240
15
135
1.09
0.06
2.7
2.8
48286.67
40055.10
ug/l
0.50
15
135
12
107
1.10
0.05
4.8
6.7
—
—
—
0
0
10
88
1.11
0.05
1.2
1.3
—
—
—
0
0
35
329
1.04
0.05
6.0
3.5
1.52
1.48
mmol/l
0.07
35
317
22
226
0.95
0.04
1.1
1.1
—
—
—
0
0
25
234
1.05
0.04
1.1
1.2
—
—
—
0
0
22
205
1.05
0.04
1.2
1.2
—
—
—
0
0
54
517
1.02
0.03
1.1
1.2
—
—
—
0
0
21
214
0.96
0.02
1.1
1.3
—
221.43
—
0
7
210
2046
1.00
0.01
1.6
1.4
—
—
—
0
0
52
516
0.99
0.01
1.2
1.2
—
—
—
0
0
20
202
0.97
0.01
1.1
1.4
4.97
5.86
u/ml
0.10
13
130
34
327
1.02
0.00
1.7
1.6
—
—
—
0
0
39
381
1.00
0.00
5.6
3.9
—
—
—
0
0
43
416
1.01
0.00
1.3
1.7
0.66
0.79
g/l
0.49
36
343
31
300
1.01
0.00
6.3
3.4
6.85
7.26
mmol/l
0.39
31
292
17
164
1.01
0.00
1.4
1.1
—
—
—
0
0
41
400
1.00
0.00
4.4
3.5
29.15
23.41
mg/l
0.43
35
251
13
130
0.98
0.00
1.1
1.0
—
—
—
0
0
43
418
1.01
0.00
1.7
1.5
0.52
0.32
nmol/l
0.41
35
340
28
270
1.02
0.00
2.0
1.4
—
—
—
0
0
14
134
1.02
0.00
1.1
1.0
—
—
—
0
0
44
426
1.01
0.00
1.5
1.5
93.60
168.25
pmol/l
0.91
44
414
22
216
1.00
0.00
1.2
1.5
—
26.00
—
0
13
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
177.86
—
0
7
5
51
0.96
-0.00
2.6
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1380.14
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
18.21
—
0
6
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
72
0.95
-0.00
1.6
3.1
—
—
—
0
0
7
71
0.96
-0.00
3.6
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1266.00
—
0
8
7
71
0.96
-0.00
7.1
5.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_SEPTA_DEFEC and mortality.

Females

Parameter HR [95% CI] p-value
Q17_SEPTA_DEFEC 1.871 [1.6, 2.18] < 0.001
Birth year 0.988 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 678 out of 17245 females with Q17_SEPTA_DEFEC died.

Males

Parameter HR [95% CI] p-value
Q17_SEPTA_DEFEC 1.71 [1.44, 2.03] < 0.001
Birth year 0.981 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 575 out of 15035 males with Q17_SEPTA_DEFEC died.

Mortality risk

Mortality risk for people of age

years, who have Q17_SEPTA_DEFEC.

N-year risk Females Males
1 0.134% 0.217%
5 0.916% 1.639%
10 2.426% 4.085%
15 4.574% 7.915%
20 7.682% 12.977%

Relationships between endpoints

Index endpoint: Q17_SEPTA_DEFEC – Septal defects

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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