Patent foramen ovale

Q17_PATENT_FORAMEN_OVALE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q21.11
  • Cause of death: ICD-10 Q21.11

2 out of 7 registries used, show all original rules.

837

4. Check minimum number of events

None

837

5. Include endpoints

None

837

6. Filter based on genotype QC (FinnGen only)

798

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 798 402 396
Unadjusted period prevalence (%) 0.16 0.14 0.18
Median age at first event (years) 50.97 48.41 53.58

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
837
Matched controls
8369
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
307.7
836
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
44.7
307.7
212
63
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
39.9
307.7
483
277
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
22.0
307.7
346
260
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
222.6
307.7
176
10
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
22.8
307.7
287
187
Q21.10
ICD-10 Finland
Persistent ostium secundum
36.9
210.2
134
43
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.4
158.0
429
1186
B01AA03
ATC
warfarin; systemic
6.9
137.6
270
541
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
5.8
122.7
301
737
XF620
NOMESCO Finland
Examination of circulation with color method
61.6
121.6
68
12
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
+∞
119.7
112
*
B01AC04
ATC
clopidogrel; oral
6.3
116.6
246
522
AA1AD
NOMESCO Finland
CT of head and brain
4.9
109.9
362
1121
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
8.7
106.8
149
203
Q21.19
ICD-10 Finland
Atrial septal defect NOS
61.1
101.8
57
10
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
10.0
95.5
116
132
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
16.1
93.3
82
56
XA800
NOMESCO Finland
Neuropsychological investigation
6.8
90.3
160
282
R4150
NOMESCO Finland
Neuropsychological rehabilitation
25.9
82.3
58
24
PA2AE
NOMESCO Finland
Ultrasound examination of brain artery
303.2
82.1
82
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
11.4
80.2
87
84
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
78.9
513
2446
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
10.6
74.6
85
88
C10AA05
ATC
atorvastatin; oral
3.5
69.0
409
1798
XF400
NOMESCO Finland
ECG with 12 standard connections
3.9
65.4
246
800
AA5PD
NOMESCO Finland
CT examination of brain pefusion
29.0
65.1
44
16
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.6
62.4
171
439
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
10.8
60.9
68
68
K90
ICPC
Stroke/cerebrovascular accident
12.1
56.5
58
51
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
89.0
52.6
58
7
R4120
NOMESCO Finland
Occupational therapy
4.9
52.6
130
305
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
23.4
52.0
38
17
XF404
NOMESCO Finland
Ambulatory ECG
4.5
48.4
132
334
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.7
42.9
62
86
APJ
HP
PFO closure
+∞
41.0
39
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
38.7
166
572
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
9.8
38.3
45
48
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
11.3
35.8
38
35
Q25.0
ICD-10 Finland
Patent ductus arteriosus
11.4
32.2
34
31
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
12.3
30.9
31
26
PA6AD
NOMESCO Finland
CT of neck arteries
6.5
29.9
50
81
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.7
29.7
57
106
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
4.6
28.7
72
169
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
36.4
27.6
35
10
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.5
27.3
102
319
I63
ICD-10 Finland
Cerebral infarction
38.1
26.3
33
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.2
26.3
116
402
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
25.1
214
1041
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
25.0
236
1200
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
24.0
279
1544
H53.4
ICD-10 Finland
Visual field defects
7.7
23.9
34
46
B01AB05
ATC
enoxaparin; parenteral
2.3
23.8
255
1364
R42
ICD-10 Finland
Dizziness and giddiness
2.4
23.6
191
905
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
23.2
218
1102
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
22.3
169
775
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
21.6
177
840
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
19.5
21.4
32
17
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
21.1
109
412
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
6.2
20.9
36
60
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.4
20.3
53
128
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
4.1
20.1
58
151
XFE00
NOMESCO Finland
Epicardial ultrasonography
7.0
19.6
30
44
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.9
19.4
97
359
WX892
NOMESCO Finland
Monitored bed care
2.9
19.2
95
350
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.5
18.4
137
619
N18
ICPC
Paralysis/weakness
7.0
17.0
26
38
Q23.11
ICD-10 Finland
Bicuspid aortic valve
7.3
17.0
25
35
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
16.7
92
359
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
12.0
16.1
29
25
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
13.9
16.1
27
20
ZXE00
NOMESCO Finland
One hour or less
1.8
15.8
347
2329
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.6
15.5
94
385
WX402
NOMESCO Finland
General anaesthesia
2.0
15.2
216
1256
WX872
NOMESCO Finland
Intensive care
3.4
15.2
56
173
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
5.2
15.1
31
61
PA7BD
NOMESCO Finland
CT angiography of neck and brain
6.6
15.0
24
37
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
14.6
300
1960
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
14.6
14
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.8
14.6
33
71
K78
ICPC
Atrial fibrillation/flutter
3.2
14.5
58
188
FFC40
NOMESCO Finland
Closure of Patent Foramen Ovale
152.5
14.5
15
*
APK
HP
ASD closure
152.5
14.5
15
*
FM2CE, ,
NOMESCO Finland
3.7
14.0
45
127
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.5
13.7
49
148
R1260
NOMESCO Finland
Evaluation of communicative skills
5.1
13.7
29
59
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
50.8
12.9
15
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
12.6
104
489
31
HP
Congenital heart failure surgery
38.1
12.2
15
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.1
12.1
51
171
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
18.4
12.1
18
10
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.3
12.1
24
46
AF1
HP
Surgery of congenital heart defect
47.4
11.9
14
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
3.5
11.6
40
118
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
11.5
360
2606
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
11.4
67
269
SPAT1263
SPAT
Sampling
1.7
11.4
322
2267
XF402
NOMESCO Finland
ECG with work load test
2.4
11.1
80
354
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
4.9
11.0
24
50
G43.9
ICD-10 Finland
Migraine, unspecified
2.6
10.6
65
267
R47.0
ICD-10 Finland
Dysphasia and aphasia
11.4
10.6
19
17
ZXY02
NOMESCO Finland
Neuropsychologist
9.3
10.5
21
23
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
10.5
79
356
C09AA05
ATC
ramipril; oral
1.9
10.5
162
956
R4110
NOMESCO Finland
Physiotherapy
1.7
10.0
235
1566
B01AF02
ATC
apixaban; oral
2.3
9.9
75
340
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
26.4
9.8
13
5
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
9.8
91
449
K89
ICPC
Transient cerebral ischaemia
12.5
9.4
16
13
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
9.3
76
355
K91
ICPC
Cerebrovascular disease
7.9
9.2
20
26
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
11.6
9.1
16
14
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
9.0
224
1509
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.0
189
1217
B01AC07
ATC
dipyridamole; systemic
4.4
8.9
22
51
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
10.8
8.8
16
15
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
8.8
140
833
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.5
8.6
53
218
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.2
8.6
34
110
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
8.6
58
250
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
9.1
8.6
17
19
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
3.4
8.5
30
90
TFP20
NOMESCO Finland
Cardiodefibrillation
2.5
8.5
52
214
SPAT1377
SPAT
Polysomnography
3.3
8.4
31
96
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
8.4
191
1256
J01CA04
ATC
amoxicillin; systemic
1.7
8.1
696
6193
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.0
8.1
36
125
I49.5
ICD-10 Finland
Sick sinus syndrome
3.7
8.1
25
69
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.9
8.0
36
126
R4130
NOMESCO Finland
Speech therapy
2.8
7.9
38
138
WX882
NOMESCO Finland
High dependency care
2.4
7.9
53
228
C07AB07
ATC
bisoprolol; oral
1.5
7.8
298
2210
FPK00
NOMESCO Finland
Implantation of electrocardiograph with loop recorder
9.5
7.8
15
16
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
7.0
7.8
18
26
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
15.2
7.7
12
8
AP2
HP
Catheterization of the right side of the heart
45.4
7.7
9
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
7.7
51
218
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
7.6
56
251
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
25.3
7.6
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
7.5
108
621
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
7.4
146
920
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
11.0
7.3
13
12
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
7.2
284
2112
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.6
7.1
39
152
XF640, ,
NOMESCO Finland
3.7
7.1
22
61
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
4.4
7.0
17
39
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
6.9
77
406
UDC00
NOMESCO Finland
Ear microscopy
2.1
6.9
65
323
C03CA01
ATC
furosemide; systemic
1.7
6.9
145
931
I63.8
ICD-10 Finland
Other cerebral infarction
8.4
6.8
14
17
WW502
NOMESCO Finland
Autotransfusion
11.0
6.8
12
11
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
5.7
6.8
18
32
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
3.3
6.7
25
78
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
22.7
6.7
9
*
207
Kela drug reimbursment
Chronic arrhythmias
1.9
6.5
78
422
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
6.5
73
386
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.7
6.5
20
55
R51.80
ICD-10 Finland
Headache
1.7
6.5
140
903
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
5.8
6.5
17
30
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.5
304
2335
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
6.4
90
513
G43.3
ICD-10 Finland
Complicated migraine
3.6
6.3
20
56
SPAT1301
SPAT
No procedures
1.5
6.3
213
1526
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.3
6.3
23
71
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.5
6.3
37
150
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
6.2
80
443
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
6.2
66
342
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
7.1
6.2
14
20
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
6.2
76
415
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.0
6.2
17
43
K84
ICPC
Heart disease other
3.3
6.2
22
67
G04BE03
ATC
sildenafil; oral
4.2
6.1
16
39
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
12.6
6.1
10
8
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
12.6
6.1
10
8
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
6.0
53
256
C10AA01
ATC
simvastatin; oral
1.5
6.0
217
1575
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.4
6.0
21
63

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
177
123
17.98
203.16
1.3
1.2
3.56
5.28
u/ml
0.40
75
54
251
348
9.87
181.85
2.5
5.3
21.12
22.45
s
2.44
199
326
384
1041
5.97
142.17
3.3
4.0
30.89
30.13
s
1.01
379
1021
606
2627
5.73
123.05
23.1
11.6
1.48
1.21
inr
7.78
201
773
451
1757
4.40
99.06
2.8
2.2
156.30
293.76
u/l
1.67
438
1667
73
40
19.90
92.55
1.1
1.2
1.09
1.05
ratio
0.56
26
16
431
1752
4.01
86.32
4.8
5.5
84.80
91.09
%
5.87
426
1720
54
27
21.31
71.00
1.3
1.3
—
—
—
0
0
364
1589
3.28
60.35
2.3
2.6
—
—
—
0
0
411
2054
2.97
51.85
2.4
2.7
—
—
—
0
0
419
2156
2.89
49.43
4.1
3.3
29.10
36.97
ng/l
0.56
302
1365
520
3007
2.93
49.01
2.8
2.8
—
—
—
0
0
614
3904
3.15
48.20
5.8
6.1
6.05
6.52
mmol/l
11.08
591
3672
37
19
20.33
47.83
1.2
1.1
—
—
—
0
0
320
1468
2.91
46.17
3.9
3.6
793.57
1108.52
ng/l
1.24
260
1229
315
1595
2.56
35.63
4.4
3.5
—
—
—
0
0
518
3484
2.28
28.57
7.5
8.2
—
—
—
0
0
140
522
3.02
28.05
3.9
3.4
—
—
—
0
0
654
4967
2.45
25.48
4.5
4.0
7.59
10.22
mm/h
7.72
617
4642
214
1055
2.38
24.24
6.2
6.6
0.81
0.82
mmol/l
0.28
205
1010
510
3603
2.06
22.31
6.5
7.8
29.92
30.70
%
0.88
491
3442
112
418
2.94
22.18
3.7
3.8
179.92
173.60
ng/l
0.05
92
381
583
4333
2.14
22.17
4.8
3.4
—
—
—
0
0
499
3504
2.05
22.12
6.7
8.1
8.61
8.52
%
0.26
480
3335
495
3480
2.03
21.70
6.5
7.8
2.94
3.01
%
0.27
475
3309
484
3379
2.02
21.59
6.5
7.9
0.70
0.67
%
0.42
464
3208
525
3777
2.05
21.48
6.0
7.6
2.03
2.07
e9/l
0.20
449
3328
513
3673
2.02
21.11
6.0
7.6
0.58
0.58
e9/l
0.12
432
3143
482
3379
2.01
21.03
10.9
10.3
0.00
0.00
e9/l
0.47
388
2698
512
3675
2.01
20.78
6.0
7.7
0.04
0.04
e9/l
0.39
431
3144
205
1060
2.24
20.36
7.0
9.2
1.12
1.17
mmol/l
1.47
194
1009
329
2041
2.01
20.14
1.5
1.5
—
—
—
0
0
439
3010
1.96
20.08
9.1
8.9
1.21
1.22
mmol/l
0.41
412
2807
520
3794
1.98
19.63
6.4
8.2
0.19
0.20
e9/l
0.45
445
3313
495
3556
1.96
19.51
6.0
7.7
54.71
54.22
%
0.42
476
3395
798
6958
4.15
19.40
19.0
14.9
3.96
3.97
mmol/l
0.66
790
6783
800
6989
4.27
19.35
16.1
13.0
19.43
22.63
mg/l
2.19
638
5340
796
6940
4.00
19.12
18.9
14.8
139.71
139.62
mmol/l
0.57
789
6781
30
19
16.32
18.91
1.3
1.1
—
—
—
0
0
26
11
24.34
18.72
1.5
1.3
—
—
—
0
0
50
130
4.03
17.39
4.4
4.8
1.92
2.68
mmol/l
1.07
34
80
49
127
4.04
17.11
4.0
4.0
54.47
55.35
%
0.19
49
127
23
9
26.21
16.97
1.0
1.1
—
—
—
0
0
47
124
3.96
16.02
3.6
3.6
3.84
4.31
e9/l
0.75
47
124
445
3271
1.77
14.48
9.9
9.1
1.21
1.22
mmol/l
0.43
330
2876
721
6171
2.21
14.37
4.8
4.3
1.88
2.28
mu/l
0.82
672
5743
194
1128
1.94
13.45
3.9
3.6
1023.88
622.48
ng/l
0.91
141
808
239
1489
1.85
13.38
3.0
2.6
1.11
1.37
mg/l
0.49
174
1142
104
479
2.34
13.25
3.9
5.5
0.06
0.19
%
0.83
32
158
107
501
2.30
13.12
4.0
5.3
0.13
0.09
%
0.25
34
181
572
4598
1.77
12.91
3.9
3.5
36.98
46.56
u/l
4.74
548
4391
527
4141
1.74
12.87
7.7
10.6
3.82
3.90
e9/l
0.37
447
3569
562
4500
1.76
12.80
4.2
4.1
—
—
—
0
0
23
21
11.23
12.58
7.0
14.9
—
—
—
0
0
104
495
2.26
12.25
4.1
4.9
0.72
0.54
%
0.50
34
190
678
5775
1.92
12.19
5.1
5.1
37.55
39.22
mmol/mol
7.56
635
5443
110
537
2.21
12.18
4.0
5.2
0.85
0.84
%
0.01
36
219
45
144
3.25
11.54
4.9
4.7
—
—
—
0
0
269
1802
1.73
11.48
3.5
2.9
—
—
—
0
0
707
6149
1.96
11.33
4.6
3.7
1.16
1.31
mmol/l
9.06
662
5764
260
1757
1.70
10.60
3.6
4.0
7.40
7.40
ph
0.23
124
323
724
6390
1.98
10.49
5.1
4.1
4.21
4.69
mmol/l
33.31
685
6033
719
6358
1.93
9.96
5.2
4.1
1.40
1.43
mmol/l
1.16
681
5969
791
7278
2.58
9.43
17.1
11.5
—
—
—
0
0
724
6446
1.91
9.40
5.5
4.5
2.43
2.83
mmol/l
29.04
687
6053
48
185
2.69
8.90
1.2
3.1
—
—
—
0
0
603
5160
1.60
8.40
4.0
3.7
14.47
14.58
pmol/l
0.59
553
4759
501
4122
1.54
8.21
4.7
4.0
491.33
1971.77
e6/l
—
6
62
36
125
2.96
8.10
2.9
2.9
17.31
16.97
%
0.19
19
70
784
7253
2.28
8.04
11.6
10.1
27.31
28.21
u/l
0.65
760
7052
152
953
1.73
7.90
1.4
1.4
350.97
523.78
titre
1.08
31
180
140
863
1.75
7.72
1.8
1.7
1290.66
1182.26
nmol/l
0.62
103
670
337
2579
1.51
7.58
3.0
2.6
—
—
—
0
0
239
1710
1.56
7.27
1.7
1.7
1.25
1.42
mmol/l
2.64
186
1484
60
283
2.21
7.22
1.1
1.5
—
10.36
—
0
9
226
1601
1.56
7.17
3.6
4.4
—
—
—
0
0
332
2557
1.49
7.12
5.5
6.4
36.56
36.32
g/l
0.35
303
2427
703
6335
1.68
7.05
18.2
16.4
14.75
14.34
%
1.05
696
6252
230
1659
1.53
6.66
3.9
3.5
0.02
0.01
estimate
0.22
127
574
197
1375
1.57
6.61
3.2
2.8
5.00
5.78
e6/l
0.32
179
1227
11
9
12.36
6.59
1.1
1.2
—
—
—
0
0
45
198
2.34
6.39
1.1
2.8
3.67
3.54
mmol/l
0.46
39
187
566
4902
1.48
6.35
7.3
7.3
84.44
87.99
u/l
0.74
530
4650
825
7907
4.02
6.28
24.7
19.1
251.41
256.30
e9/l
1.24
805
7688
264
1982
1.48
6.25
2.9
3.5
2.36
2.36
mmol/l
0.42
224
1795
825
7911
3.98
6.20
24.7
19.0
89.86
89.65
fl
0.57
819
7826
825
7912
3.97
6.17
24.7
19.0
29.99
30.00
pg
0.10
819
7826
825
7913
3.96
6.15
24.8
19.1
6.76
6.72
e9/l
0.16
807
7672
825
7913
3.96
6.15
24.7
19.0
4.56
4.58
e12/l
0.56
805
7673
825
7917
3.93
6.06
25.0
19.2
135.73
136.65
g/l
1.01
819
7829
824
7903
3.74
6.03
25.2
19.4
40.35
40.51
%
0.35
800
7522
87
506
1.80
5.83
4.4
4.6
—
—
—
0
0
218
1594
1.50
5.82
2.9
2.5
3.22
2.91
mg/l
0.87
189
1394
43
196
2.26
5.66
1.2
3.0
130.30
653.77
e6/l
0.70
33
150
43
196
2.26
5.66
1.2
3.0
8.03
9.32
e6/l
0.06
32
145
677
6140
1.54
5.56
4.4
4.0
5.66
5.86
mmol/l
4.70
611
5695
37
162
2.34
5.35
1.2
1.2
—
—
—
0
0
9
8
11.35
5.30
1.1
1.1
—
—
—
0
0
394
3264
1.39
5.19
3.7
3.3
0.02
0.01
estimate
0.34
126
556
85
515
1.72
4.96
2.2
2.3
21.23
21.13
au/ml
—
6
40
389
3235
1.38
4.92
4.7
4.6
0.00
0.00
estimate
0.50
128
593
17
53
3.25
4.63
1.8
1.4
46.83
58.32
%
0.54
12
41
58
320
1.87
4.62
1.6
2.1
—
—
—
0
0
387
3241
1.36
4.58
3.6
3.3
0.00
0.00
estimate
0.50
128
616
262
2063
1.39
4.54
3.6
3.5
33.89
87.97
e6/l
0.92
210
1576
28
117
2.44
4.51
5.7
4.2
—
—
—
0
0
21
76
2.81
4.47
2.5
2.3
30.67
33.51
pg
1.53
21
76
19
65
2.97
4.46
2.6
1.9
—
—
—
0
0
123
841
1.54
4.43
1.3
1.3
—
—
—
0
0
242
1887
1.40
4.42
3.2
3.4
0.23
0.37
e6/l
0.70
193
1411
171
1254
1.46
4.39
1.5
1.5
19.75
20.86
nmol/l
0.49
130
1091
248
1953
1.38
4.25
2.4
2.8
56.66
61.17
u/l
0.83
224
1842
179
1332
1.44
4.24
3.2
2.9
532.83
570.69
mosm/kgh2o
1.44
161
1148
238
1864
1.39
4.21
3.2
3.4
—
—
—
0
0
322
2661
1.34
4.01
2.8
3.1
6.01
5.91
ph
0.31
34
284
118
820
1.51
3.95
12.2
7.9
7.41
7.40
ph
0.13
14
51
28
127
2.25
3.80
5.1
5.6
—
—
—
0
0
269
2179
1.35
3.78
1.9
1.9
98.59
95.92
pmol/l
0.49
142
1177
110
760
1.51
3.78
1.2
1.2
—
—
—
0
0
381
3246
1.32
3.78
6.6
7.3
14.02
14.64
umol/l
0.18
356
3102
140
1019
1.45
3.72
2.7
2.8
203.25
111.75
ug/g
0.61
107
827
150
1106
1.43
3.72
1.3
1.3
14.80
33.39
iu/ml
4.85
42
340
356
3018
1.31
3.61
3.8
3.0
84.44
117.11
ug/l
4.12
317
2837
121
861
1.47
3.61
3.0
2.9
21.34
23.78
%
1.28
105
769
317
2657
1.31
3.45
3.1
2.7
74.94
74.71
nmol/l
0.05
281
2432
148
1106
1.41
3.40
1.7
1.6
441.51
25026720.54
pmol/l
1.00
103
951
13
42
3.13
3.38
1.8
1.6
15.00
30.16
%
—
7
32
32
162
2.01
3.33
4.2
11.6
—
—
—
0
0
239
1936
1.33
3.30
4.7
8.3
—
—
—
0
0
29
143
2.06
3.24
3.0
2.6
134.35
132.11
g/l
0.20
23
109
101
713
1.47
3.14
1.4
1.3
—
—
—
0
0
126
928
1.42
3.14
3.0
2.8
2.46
2.39
g/l
0.86
112
879
71
466
1.57
3.10
2.8
2.5
6.32
6.58
e9/l
0.04
54
413
68
444
1.58
3.04
1.8
2.9
65.97
66.25
g/l
0.12
61
414
53
325
1.67
3.03
14.2
14.6
—
—
—
0
0
11
31
3.58
3.00
5.0
9.5
—
—
—
0
0
134
1006
1.40
2.99
3.0
2.8
12.28
14.02
umol/l
2.18
122
954
33
176
1.91
2.99
7.5
9.6
1.11
1.29
mmol/l
0.71
28
155
16
63
2.57
2.97
2.7
2.5
0.87
0.98
nmol/l
0.30
11
48
15
59
2.57
2.79
1.7
1.6
—
—
—
0
0
66
439
1.55
2.74
2.4
2.3
14.12
7.97
ug/l
1.15
58
394
12
40
3.03
2.70
1.3
1.2
—
—
—
0
0
10
29
3.48
2.69
1.0
1.1
1364.60
1612.45
miu/ml
—
10
29
20
94
2.16
2.56
1.9
1.4
—
—
—
0
0
105
777
1.40
2.56
1.5
1.5
—
—
—
0
0
48
301
1.63
2.56
4.7
6.2
0.42
0.36
g/l
0.14
30
180
6
11
5.48
2.54
3.0
4.6
4.38
4.53
mmol/l
—
6
11
52
334
1.59
2.52
5.3
6.7
—
—
—
0
0
282
2405
1.26
2.52
4.3
4.2
40.75
87.01
e6/l
1.05
219
1686
40
241
1.69
2.48
1.6
2.2
1.41
1.40
g/l
0.02
32
218
92
671
1.42
2.44
12.9
8.0
—
—
—
0
0
9
27
3.36
2.39
1.6
1.2
—
—
—
0
0
8
22
3.66
2.36
2.8
2.0
—
—
—
0
0
109
824
1.37
2.35
10.1
10.9
—
—
—
0
0
135
1057
1.33
2.32
1.3
1.2
9.20
9.68
u/ml
0.02
42
420
81
584
1.43
2.30
4.7
3.9
76.49
70.20
e9/l
0.70
57
423
8
23
3.50
2.27
1.1
1.1
155.37
189.33
mmol/24h
—
8
23
88
649
1.40
2.21
9.9
10.4
0.62
0.87
mmol/l
0.25
71
534
283
2445
1.24
2.21
1.9
2.0
—
—
—
0
0
104
789
1.36
2.20
4.8
4.7
1.83
1.66
%
0.56
85
735
7
19
3.71
2.15
6.9
1.5
—
—
—
0
0
32
190
1.71
2.13
1.5
1.4
293.71
320.83
ug/g
0.32
17
112
8
25
3.22
2.10
1.0
1.2
—
—
—
0
0
30
176
1.73
2.08
1.1
1.2
13.88
11.84
u/ml
—
5
28
121
948
1.32
2.08
2.5
2.8
2.42
2.44
mmol/l
0.81
105
833
236
2011
1.24
2.07
4.6
4.1
1.67
2.01
ug/l
0.75
192
1838
17
83
2.07
2.02
4.5
17.5
11.66
11.70
%
0.02
17
83
11
44
2.52
2.01
1.9
2.2
526.67
597.44
ml
—
6
25
71
515
1.41
1.98
6.2
5.9
66.93
72.52
ng/l
0.40
61
474
196
1653
1.24
1.88
2.8
2.6
—
—
—
0
0
19
100
1.92
1.86
1.3
3.2
—
—
—
0
0
18
94
1.93
1.81
1.0
1.2
—
—
—
0
0
191
1618
1.23
1.76
3.2
3.1
3267.31
5037.01
umol/l
0.24
167
1473
15
74
2.05
1.75
2.3
3.1
—
—
—
0
0
6
18
3.35
1.75
7.5
14.1
—
—
—
0
0
13
61
2.15
1.72
35.5
39.2
7.15
6.97
ug/l
0.12
13
53
5
13
3.86
1.71
2.0
3.2
—
—
—
0
0
14
69
2.05
1.65
1.1
1.2
—
—
—
0
0
19
105
1.83
1.64
1.1
1.1
1.46
1.46
g/l
0.01
19
96
10
211
0.47
1.64
15.3
10.1
—
—
—
0
0
18
98
1.85
1.62
7.1
7.7
12.88
10.35
mg/l
0.62
13
92
10
43
2.34
1.59
1.3
1.3
1.49
1.49
g/l
—
10
43
7
26
2.71
1.58
2.1
2.4
12.36
19.67
umol/l
—
7
26
7
26
2.71
1.58
3.4
2.6
0.99
1.09
umol/l
—
7
26
18
99
1.84
1.58
1.1
1.6
—
—
—
0
0
22
130
1.71
1.54
1.2
1.2
—
—
—
0
0
219
1906
1.20
1.53
1.5
1.5
1.09
2.44
u/ml
2.15
62
459
11
51
2.17
1.51
2.6
3.2
1.00
2.41
u/field
—
6
27
6
21
2.87
1.50
2.0
1.5
23.70
17.66
umol/l
—
6
21
6
21
2.87
1.50
2.5
2.6
—
—
—
0
0
117
1418
0.80
1.50
4.1
3.5
1.02
1.02
kg/l
0.13
20
223
103
830
1.27
1.47
4.8
4.6
5.54
8.26
umol/l
2.36
88
725
15
80
1.89
1.45
1.7
3.8
—
—
—
0
0
11
52
2.13
1.45
1.3
1.7
0.88
1.02
g/l
0.55
11
52
36
247
1.48
1.40
1.4
1.4
0.23
0.23
g/l
0.19
36
239
29
190
1.55
1.39
2.8
2.6
—
—
—
0
0
33
223
1.50
1.38
1.7
1.7
—
—
—
0
0
33
224
1.49
1.35
2.0
2.2
5.95
2.33
ug/l
0.46
24
207
110
904
1.25
1.35
2.3
2.1
—
—
—
0
0
30
203
1.50
1.26
2.6
3.3
—
—
—
0
0
202
1778
1.18
1.24
1.5
1.6
2.08
2.15
g/l
0.31
130
1043
5
19
2.64
1.21
1.0
1.6
89.80
74.84
nmol/24h
—
5
19
8
38
2.12
1.18
1.0
1.1
—
—
—
0
0
12
64
1.89
1.18
4.6
4.7
—
—
—
0
0
72
573
1.28
1.17
16.9
8.6
9.23
9.42
kpa
0.40
72
554
65
511
1.29
1.16
1.4
1.2
91.94
151.49
iu/ml
0.90
21
208
29
199
1.47
1.16
3.3
4.4
28.85
36.70
umol/l
1.84
29
183
17
271
0.62
1.15
2.5
2.9
—
—
—
0
0
12
65
1.86
1.13
6.8
3.5
23.00
26.85
umol/l
0.70
12
65
80
649
1.26
1.12
2.4
3.1
10.01
9.73
g/l
0.32
75
608
38
277
1.39
1.11
1.2
1.2
—
—
—
0
0
29
203
1.44
1.06
1.3
1.1
—
—
—
0
0
29
204
1.44
1.04
1.3
1.1
—
—
—
0
0
19
122
1.57
1.03
1.3
4.0
—
—
—
0
0
13
75
1.74
1.03
4.3
4.4
—
—
—
0
0
7
34
2.07
1.03
2.0
3.3
41628.57
38006.03
ug/l
—
7
34
133
1529
0.85
1.01
3.0
3.3
—
—
—
0
0
55
432
1.29
1.01
1.9
1.8
23.47
23.10
iu/l
0.03
46
336
16
99
1.63
1.00
1.0
1.1
3.14
6.04
iu/ml
—
5
19
17
107
1.60
1.00
3.5
1.9
78.12
69.87
mmol/l
0.36
17
95
7
35
2.01
1.00
7.7
7.7
2.02
2.17
mg/l
—
7
27
7
35
2.01
1.00
3.3
2.0
2534.29
2105.50
ml
—
7
30
40
301
1.35
0.99
1.8
2.3
8843.53
3659.22
u/l
0.52
15
118
9
49
1.85
0.98
1.1
1.1
—
—
—
0
0
48
372
1.31
0.98
1.1
1.2
—
—
—
0
0
162
1430
1.16
0.97
1.6
1.9
—
—
—
0
0
51
400
1.29
0.96
3.3
3.4
4.69
4.72
pmol/l
0.11
42
357
18
117
1.55
0.94
3.7
4.7
—
—
—
0
0
6
29
2.08
0.89
1.5
1.7
—
—
—
0
0
78
652
1.22
0.87
2.2
2.2
12.29
12.54
nmol/l
0.09
68
586
6
113
0.53
0.83
1.0
2.0
—
—
—
0
0
10
58
1.73
0.80
1.5
1.9
—
—
—
0
0
135
1195
1.15
0.79
2.8
2.7
0.81
0.72
ug/l
0.28
80
695
8
48
1.67
0.79
4.1
3.7
—
—
—
0
0
6
34
1.77
0.76
1.3
1.3
—
—
—
0
0
15
219
0.68
0.74
1.0
1.1
—
—
—
0
0
72
609
1.20
0.73
2.4
2.5
60.97
111.19
u/l
0.27
63
526
9
56
1.61
0.72
6.0
8.7
4846.84
91.61
g/mol
—
9
47
39
310
1.27
0.70
2.3
2.4
—
—
—
0
0
15
101
1.49
0.70
1.1
1.2
—
—
—
0
0
9
58
1.56
0.70
1.1
2.2
—
—
—
0
0
9
59
1.53
0.68
3.7
3.3
2.53
2.27
mmol/l
—
9
54
102
897
1.16
0.67
7.5
8.0
1.49
1.32
mmol/l
0.20
83
726
5
28
1.79
0.66
1.8
1.1
—
—
—
0
0
5
28
1.79
0.66
1.8
1.1
—
—
—
0
0
5
28
1.79
0.66
1.8
1.1
—
—
—
0
0
29
370
0.78
0.64
3.4
2.3
—
—
—
0
0
6
104
0.57
0.62
1.7
1.5
—
—
—
0
0
5
30
1.67
0.61
1.4
4.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.9
—
—
—
0
0
0
21
0.00
0.60
0.0
3.0
—
29.19
—
0
21
0
22
0.00
0.59
0.0
2.1
—
4407.29
—
0
14
6
35
1.72
0.57
2.0
1.3
107.00
148.10
nmol/l
—
6
35
15
107
1.41
0.55
2.1
2.5
—
—
—
0
0
9
60
1.51
0.54
1.7
2.1
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
47
554
0.84
0.53
1.6
1.5
—
—
—
0
0
6
40
1.50
0.51
1.5
1.3
—
—
—
0
0
6
40
1.50
0.51
2.0
3.1
318.67
814.98
u/ml
—
6
40
6
41
1.47
0.50
1.5
1.5
—
—
—
0
0
30
244
1.24
0.48
1.8
1.9
—
—
—
0
0
22
172
1.29
0.48
2.0
1.9
3.75
5.96
iu/l
—
6
57
7
46
1.53
0.48
1.6
1.4
—
—
—
0
0
48
411
1.18
0.47
1.6
1.6
—
—
—
0
0
15
111
1.36
0.47
1.1
1.2
—
—
—
0
0
72
810
0.88
0.46
1.3
1.4
—
—
—
0
0
16
120
1.34
0.46
1.2
1.3
—
—
—
0
0
241
2277
1.08
0.46
4.1
3.9
30.94
33.91
u/l
0.68
225
2191
7
49
1.43
0.46
1.9
2.8
—
—
—
0
0
5
82
0.61
0.46
1.4
1.4
—
—
—
0
0
14
103
1.37
0.45
1.0
1.1
—
—
—
0
0
17
219
0.77
0.44
3.0
3.3
11.24
1177.41
u/ml
1.00
17
191
64
721
0.88
0.43
1.7
1.4
—
—
—
0
0
171
1598
1.09
0.43
3.3
3.3
479.74
269.95
mg/l
0.20
99
1071
31
258
1.21
0.42
1.9
1.8
363.00
202.72
u/ml
1.45
16
143
5
32
1.57
0.42
3.8
8.4
—
—
—
0
0
10
139
0.72
0.42
2.1
3.8
—
—
—
0
0
208
1963
1.08
0.41
3.6
3.6
8.04
8.03
mmol/l
0.01
165
1720
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.4
—
9.63
—
0
10
8
59
1.36
0.41
1.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.9
—
—
—
0
0
178
1674
1.08
0.39
3.9
3.9
116.64
9.53
mg/mmol
0.50
105
1094
12
159
0.75
0.38
1.0
1.1
5.03
0.41
u/ml
—
5
69
5
36
1.39
0.38
7.4
5.9
—
37.79
—
0
7
120
1113
1.09
0.37
1.5
1.7
—
—
—
0
0
6
43
1.40
0.35
1.8
2.5
—
—
—
0
0
10
73
1.37
0.34
1.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.1
190.88
225.59
iu/ml
—
6
44
12
155
0.77
0.33
1.1
1.1
1.34
3.02
u/ml
—
5
60
47
418
1.13
0.31
1.2
1.2
—
—
—
0
0
7
54
1.30
0.30
2.7
2.0
—
—
—
0
0
10
75
1.34
0.30
1.0
1.3
4.00
7.00
u/ml
—
5
52
7
55
1.27
0.30
1.0
1.1
—
—
—
0
0
7
56
1.25
0.29
1.0
1.0
—
—
—
0
0
16
195
0.82
0.29
3.1
4.4
1.23
1.36
mmol/l
0.33
16
189
80
739
1.09
0.28
1.2
1.2
—
—
—
0
0
9
120
0.75
0.27
1.0
1.0
—
—
—
0
0
26
224
1.17
0.27
1.1
1.2
—
—
—
0
0
13
161
0.80
0.27
1.2
1.3
—
—
—
0
0
27
234
1.16
0.26
1.8
1.9
99.00
101.93
u/ml
—
7
34
5
74
0.67
0.26
1.0
1.4
—
—
—
0
0
29
330
0.87
0.25
1.1
1.1
—
—
—
0
0
43
387
1.12
0.25
1.5
1.7
—
—
—
0
0
45
497
0.90
0.25
1.5
1.4
—
—
—
0
0
20
170
1.18
0.24
2.1
1.6
—
—
—
0
0
57
523
1.10
0.24
1.7
1.5
—
—
—
0
0
15
180
0.83
0.24
1.5
1.7
—
—
—
0
0
10
126
0.79
0.24
1.4
1.2
—
—
—
0
0
77
717
1.08
0.24
1.6
1.7
—
—
—
0
0
23
264
0.87
0.23
1.0
1.2
4.98
6.14
u/ml
0.12
12
180
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
24
272
0.88
0.21
1.6
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
6
49
1.23
0.20
1.0
1.5
93.50
75.22
umol/l
—
6
49
35
317
1.11
0.20
3.4
7.1
0.74
0.64
%
1.20
35
317
23
260
0.88
0.19
1.0
1.2
0.54
1.02
u/ml
0.59
12
164
25
222
1.13
0.19
3.3
5.2
—
—
—
0
0
6
52
1.15
0.19
2.3
2.2
—
—
—
0
0
79
745
1.07
0.19
1.4
1.8
—
—
—
0
0
11
132
0.83
0.18
3.6
5.0
373.18
379.39
umol/l
0.06
11
120
8
69
1.16
0.16
3.3
4.4
—
85.07
—
0
21
53
497
1.07
0.15
3.6
4.5
3.14
21.80
ug/l
1.17
43
404
19
169
1.13
0.14
1.0
1.2
—
—
—
0
0
7
86
0.81
0.14
3.3
1.4
—
—
—
0
0
12
139
0.86
0.14
1.5
1.4
—
—
—
0
0
12
139
0.86
0.14
1.5
1.4
—
—
—
0
0
47
442
1.07
0.13
1.2
1.4
—
—
—
0
0
29
267
1.09
0.13
1.7
2.6
—
—
—
0
0
11
94
1.17
0.13
1.1
1.3
—
—
—
0
0
33
306
1.08
0.13
1.4
2.0
—
—
—
0
0
10
85
1.18
0.12
4.4
1.3
0.55
0.58
nmol/l
—
10
79
10
114
0.88
0.09
2.4
3.7
39.21
37.10
%
—
10
114
10
87
1.15
0.09
1.4
1.6
281.80
288.54
mosm/kgh2o
—
10
61
17
186
0.91
0.09
1.6
2.3
—
—
—
0
0
43
451
0.95
0.09
2.3
3.4
—
—
—
0
0
24
257
0.93
0.08
1.0
1.2
3.92
2.71
u/ml
0.17
14
169
13
144
0.90
0.08
1.5
1.5
—
—
—
0
0
6
58
1.03
0.08
1.0
1.2
112.88
167.41
pmol/l
—
6
58
5
60
0.83
0.08
1.2
1.8
—
—
—
0
0
36
342
1.05
0.08
5.0
3.0
0.16
0.14
e6/l
0.10
36
330
113
1157
0.97
0.08
1.6
1.7
—
—
—
0
0
23
246
0.93
0.08
1.0
1.1
0.62
8.54
u/ml
—
6
40
7
67
1.05
0.08
1.1
1.1
—
—
—
0
0
16
174
0.92
0.07
1.0
1.1
—
—
—
0
0
6
73
0.82
0.07
1.3
1.8
—
—
—
0
0
13
143
0.91
0.07
1.3
1.4
41.48
146.56
pmol/l
0.80
13
138
8
76
1.05
0.07
4.7
1.3
—
—
nmol/l
—
0
0
7
80
0.87
0.07
5.7
1.3
—
—
—
0
0
38
363
1.05
0.07
1.4
2.2
—
—
—
0
0
7
84
0.83
0.07
1.0
1.1
—
—
—
0
0
9
105
0.86
0.06
4.2
3.7
—
—
—
0
0
40
387
1.04
0.04
1.4
2.1
—
—
—
0
0
40
389
1.03
0.03
1.4
2.1
—
—
—
0
0
18
171
1.05
0.03
1.0
1.1
15.48
7.76
u/ml
—
10
85
91
898
1.01
0.02
1.5
1.7
—
—
—
0
0
14
148
0.94
0.02
1.3
1.2
—
—
—
0
0
40
391
1.02
0.02
1.4
2.1
—
—
—
0
0
116
1171
0.99
0.02
2.6
3.1
1.04
0.83
e6/l
0.20
65
660
12
127
0.94
0.01
1.0
1.0
—
—
—
0
0
13
137
0.95
0.01
4.5
1.9
—
—
—
0
0
113
1137
0.99
0.01
3.2
3.2
2.69
1.70
e6/l
0.92
59
631
26
254
1.02
0.00
1.3
1.4
159.94
244.92
miu/ml
—
10
121
18
183
0.98
0.00
1.1
1.1
8.63
8.11
u/ml
—
9
104
86
855
1.01
0.00
1.9
1.7
—
—
—
0
0
41
413
0.99
0.00
1.2
1.1
—
2.90
—
0
5
14
143
0.98
0.00
2.6
2.3
32.83
100.28
ug/min
—
6
85
14
135
1.04
0.00
1.1
1.1
—
—
—
0
0
10
98
1.02
0.00
1.5
1.5
—
—
—
0
0
39
386
1.01
0.00
1.3
2.2
—
—
—
0
0
29
285
1.02
0.00
1.0
1.2
0.84
1.98
u/ml
1.02
15
188
34
340
1.00
0.00
2.5
1.9
6.37
7.68
u/l
0.27
26
235
34
345
0.98
0.00
1.1
1.1
—
—
—
0
0
5
54
0.93
0.00
1.0
1.0
167.40
165.30
g/l
—
5
54
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
17.04
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
71
0.99
-0.00
1.3
1.8
3.91
5.25
u/ml
—
7
71
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
2.36
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
6.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
19.18
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
435.60
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.4
—
—
—
0
0
9
93
0.97
-0.00
1.7
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
190.40
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_PATENT_FORAMEN_OVALE – Patent foramen ovale

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).