Graves disease: Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland ( hyperthyroidism ).It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism andoccurs mostoften in women over age 20. However, the disorder may occur at any age and may affect males as well.Treatmentmayinclude radioiodine therapy , antithyroid drugs, and/or thyroid surgery.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
6542 |
4. Check minimum number of eventsNone |
6542 |
5. Include endpointsNone |
6542 |
6. Filter based on genotype QC (FinnGen only) |
6304 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E05
- Name in latin
- Thyreotoxicosis cum struma diffusa
Similar endpoints
↥List of similar endpoints to
Thyrotoxicosis with diffuse goitre
based on the number of shared cases.
Similar with more cases:
- Thyrotoxicosis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 38371 | 31186 | 6900 |
| Only index persons | 35764 | 29429 | 6335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.76 | 0.89 | 0.19 |
| Only index persons | 0.93 | 1.08 | 0.24 |
| Median age at first event (years) | |||
| Whole population | 49.44 | 49.13 | 51.36 |
| Only index persons | 48.69 | 48.33 | 50.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6304 | 5280 | 1024 |
| Unadjusted period prevalence (%) | 1.64 | 1.87 | 0.47 |
| Median age at first event (years) | 50.04 | 49.03 | 55.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 6541
- Matched controls
- 65410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.4
315.2
665
1340
H03BB01
ATC
carbimazole; oral
5214.4
307.7
5362
57
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
1249.7
307.7
571
5
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
11512.2
307.7
991
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
3182.4
307.7
2760
15
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
31.4
307.7
271
90
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
353.7
307.7
991
33
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
4503599627370496.0
307.7
6074
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
733
*
E03
ICD-10 Finland
Other hypothyroidism
120.4
307.7
719
67
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
33.3
307.7
462
149
T86
ICPC
Hypothyroidism/myxoedema
103.8
307.7
646
69
H03AA01
ATC
levothyroxine sodium; systemic
189.4
307.7
4662
846
T85
ICPC
Hyperthyroidism/thyrotoxicosis
211.0
307.7
359
18
C07AA05
ATC
propranolol; systemic
4.7
307.7
2764
8793
E03.89
ICD-10 Finland
Other specified hypothyroidism
160.1
307.7
597
41
104
Kela drug reimbursment
Thyroid insufficiency
1821.4
307.7
1835
14
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
151.0
307.7
247
17
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
27.8
307.7
366
139
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
142.4
307.7
1539
141
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
10491.5
307.7
916
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
93.0
307.7
259
29
BAA60
NOMESCO Finland
Total thyroidectomy
2610.8
307.7
1354
7
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
5194.8
307.7
492
*
C07AB07
ATC
bisoprolol; oral
2.6
298.0
3388
19313
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
133.7
260.2
131
10
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
2491.5
259.9
250
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
35.9
257.2
161
46
H062, E050,
ICD-10 Finland
+∞
226.4
216
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
85.8
223.6
118
14
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
215.8
206
*
E06.3
ICD-10 Finland
Autoimmune thyroiditis
39.9
212.0
129
33
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
202.1
193
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
12.0
187.6
190
162
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
78.1
187.0
100
13
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
13.0
186.5
180
142
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
184.0
2528
14769
H05.2
ICD-10 Finland
Exophthalmic conditions
38.3
183.8
113
30
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
+∞
183.2
175
*
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
176.9
169
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
162.8
3168
20782
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
157.9
151
*
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
148.5
142
*
H03BA02
ATC
propylthiouracil; oral
+∞
141.1
135
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
43.7
137.7
82
19
106
Kela drug reimbursment
Hypoparathyroidism
66.2
131.1
72
11
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
15.1
128.1
113
76
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.2
126.5
349
864
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.3
123.7
139
138
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
1200.6
121.3
118
*
CA1AD
NOMESCO Finland
Orbita CT
28.2
115.8
78
28
A11CC03
ATC
alfacalcidol; systemic
5.8
108.5
201
355
E06.9
ICD-10 Finland
Thyroiditis, unspecified
46.6
102.1
60
13
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
14.0
93.8
86
62
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
6.1
93.3
163
272
E83.51
ICD-10 Finland
Hypocalcemia
13.0
85.3
82
64
E05.5
ICD-10 Finland
Thyroid crisis or storm
+∞
83.5
80
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
112.8
82.1
89
8
H50.2
ICD-10 Finland
Vertical strabismus
7.6
74.5
106
142
H53.2
ICD-10 Finland
Diplopia
3.6
72.7
252
730
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
33.1
71.6
46
14
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
67.8
65
*
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
62.6
60
*
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
61.5
59
*
H02AB06
ATC
prednisolone; systemic
1.5
58.9
2927
22651
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
57.4
55
*
A11CC02
ATC
dihydrotachysterol; oral
22.9
56.3
41
18
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.9
56.1
270
953
C07AB02
ATC
metoprolol; systemic
1.8
56.0
1060
6473
H50.8
ICD-10 Finland
Other specified strabismus
18.8
54.4
43
23
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
532.4
53.6
53
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
53.3
815
4662
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
53.2
51
*
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
14.9
51.9
46
31
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.6
51.9
319
1277
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
51.3
1055
6581
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
48.8
632
3420
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.3
48.6
186
574
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
481.5
48.4
48
*
H02AB09
ATC
hydrocortisone; systemic
3.6
45.8
153
433
R00.2
ICD-10 Finland
Palpitations
2.0
45.6
560
2974
ZXA10
NOMESCO Finland
Bilateral
1.6
44.0
1061
6876
T89
ICPC
Diabetes insulin dependent
2.7
43.4
238
900
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
42.2
868
5391
H04AA01
ATC
glucagon; nasal, parenteral
3.3
41.1
154
469
XCK00
NOMESCO Finland
Perimetry
2.1
40.0
383
1857
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
39.2
2077
15905
TFP20
NOMESCO Finland
Cardiodefibrillation
2.3
39.0
317
1438
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
7.6
38.1
54
72
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
11.9
37.6
38
32
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
37.5
36
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
7.3
37.2
54
74
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
36.6
2385
18901
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
54.1
36.4
43
8
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
36.3
1476
10710
C01BD01
ATC
amiodarone; systemic
3.4
36.3
133
400
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
5.6
35.9
68
123
H50.6
ICD-10 Finland
Mechanical strabismus
58.9
35.2
41
7
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
181.0
34.8
36
*
24220
ICD-8 Finland
Thyrotoxicosis with or without goitre, Thyrotoxicosis without mention of goitre
+∞
34.4
33
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.2
34.0
137
437
A10AB04
ATC
insulin lispro; parenteral
2.7
33.0
186
714
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
32.9
1242
8853
CAC44
NOMESCO Finland
Combined decompression of orbit
170.9
32.7
34
*
WX402
NOMESCO Finland
General anaesthesia
1.5
32.2
1257
9017
A10AB01
ATC
insulin (human); parenteral
2.6
31.8
193
768
C07AA07
ATC
sotalol; systemic
2.7
31.6
167
620
K90.0
ICD-10 Finland
Coeliac disease
2.5
31.4
199
808
H02AB07
ATC
prednisone; oral
1.6
30.8
785
5123
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.7
30.4
33
31
R53
ICD-10 Finland
Malaise and fatigue
1.5
30.3
1366
10062
R06.0
ICD-10 Finland
Dyspnoea
1.4
30.1
1404
10410
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
29.4
1164
8358
ZX120
NOMESCO Finland
Intravenous
1.7
29.0
520
3095
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
10.7
28.6
31
29
A10AB05
ATC
insulin aspart; parenteral
1.9
28.2
357
1911
CAC20
NOMESCO Finland
Lateral decompression of orbit
282.7
27.8
28
*
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
282.7
27.8
28
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.7
26.8
145
546
K04
ICPC
Palpitations/awareness of heart
1.9
26.7
329
1745
A10AA01, ,
ATC
2.7
26.4
147
561
H3600, E103,
ICD-10 Finland
4.0
26.3
73
182
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
25.8
2268
18574
C03CA01
ATC
furosemide; systemic
1.4
25.7
1239
9208
A02BC02
ATC
pantoprazole; systemic
1.3
25.1
4020
35764
E05.3
ICD-10 Finland
Thyrotoxicosis from ectopic thyroid tissue
+∞
25.0
24
*
A04
ICPC
Weakness/tiredness general
1.5
24.8
799
5486
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
7.5
24.6
35
47
207
Kela drug reimbursment
Chronic arrhythmias
1.6
24.5
606
3917
B03BA03
ATC
hydroxocobalamin; parenteral
2.1
24.5
248
1228
A10AA02, ,
ATC
2.4
24.4
163
679
A10AE05
ATC
insulin detemir; parenteral
2.0
24.2
250
1247
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.9
24.0
109
374
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
23.8
1505
11690
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
23.6
2145
17594
107
Kela drug reimbursment
Pernicious anaemia
3.2
23.5
92
289
A10AC01
ATC
insulin (human); parenteral
1.8
23.2
347
1958
N02BE01
ATC
paracetamol; systemic, rectal
1.4
23.2
5561
52204
K80
ICPC
Cardiac arrhythmia NOS
1.7
22.8
433
2617
A10AE04
ATC
insulin glargine; parenteral
1.7
22.6
413
2470
2AB04, ,
NOMESCO Finland
6.8
22.5
35
52
K29.4
ICD-10 Finland
Chronic atrophic gastritis
2.9
22.4
102
350
T81
ICPC
Goitre
8.3
22.2
29
35
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
21.9
21
*
E05.81
ICD-10 Finland
Overproduction of thyroid-stimulating hormone
+∞
21.9
21
*
A10AE06
ATC
insulin degludec; parenteral
2.2
21.3
171
773
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
21.2
608
4062
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
21.1
437
2702
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
20.9
1023
7591
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
77.0
20.7
23
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
20.5
690
4772
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
4.0
20.2
57
144
WF099
NOMESCO Finland
Other radiotherapy
4.4
20.0
49
111
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.6
19.8
112
432
E89.9
ICD-10 Finland
Postprocedural endocrine and metabolic disorder, unspecified
+∞
19.8
19
*
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
19.8
758
5376
SPAT1097
SPAT
Recording of ECG
1.5
19.8
685
4763
H3601, E103,
ICD-10 Finland
4.0
19.5
54
135
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.7
19.2
338
1999
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
18.9
475
3078
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
18.9
786
5661
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
18.8
18
*
E06.4
ICD-10 Finland
Drug-induced thyroiditis
+∞
18.8
18
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
18.7
540
3612
Z3231
NOMESCO Finland
Registered nurse
1.3
18.7
1404
11135
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
18.6
964
7214
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
18.3
1201
9332
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
18.1
4330
39628
BA1AE, ,
SPAT
3.2
18.1
71
224
B01AA03
ATC
warfarin; systemic
1.5
17.9
693
4918
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
52.6
17.9
21
*
N05CF01
ATC
zopiclone; oral
1.3
17.9
1667
13610
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
17.7
17
*
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
+∞
17.7
17
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.6
17.7
98
375
E20.8
ICD-10 Finland
Other hypoparathyroidism
95.3
17.6
19
*
E06.0
ICD-10 Finland
Acute thyroiditis
28.8
17.4
23
8
H50.0
ICD-10 Finland
Convergent concomitant strabismus
3.7
17.0
53
144
C01AA05
ATC
digoxin; systemic
1.8
16.9
267
1532
E07.89
ICD-10 Finland
Other specified disorders of thyroid
25.6
16.9
23
9
CEW99
NOMESCO Finland
Other operation on extraocular muscle
19.3
16.8
25
13
ZXE00
NOMESCO Finland
One hour or less
1.3
16.7
2179
18527
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
90.3
16.6
18
*
O90.5
ICD-10 Finland
Postpartum thyroiditis
170.4
16.5
17
*
CA1BD
NOMESCO Finland
Extensive orbita CT
23.1
16.4
23
10
A12AA04
ATC
calcium carbonate; oral
3.1
16.3
68
223
A60
ICPC
General and Unspecified, Result test/procedure
1.8
16.2
224
1235
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
16.7
16.0
25
15
R03AC02
ATC
salbutamol; inhalant
1.2
16.0
3258
29076
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
16.0
1545
12646
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
15.9
1353
10890
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.5
15.8
443
2943
B81
ICPC
Anaemia vit B12/folate deficiency
2.1
15.8
153
747
SPAT1262
SPAT
Handing over of treatment supplies
1.4
15.8
755
5566
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
15.7
323
1992
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
15.6
15
*
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.6
15.6
92
363
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.3
15.5
58
178
105
Kela drug reimbursment
Adrenal cortical hypofunction
13.7
15.5
26
19
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
15.4
300
1824
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.5
15.4
51
145
SPAT1263
SPAT
Sampling
1.2
14.9
2312
19978
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
4.1
14.9
40
98
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
+∞
14.6
14
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
14.5
3262
29286
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
2.7
14.5
75
278
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
3.0
14.4
63
213
J01DB01
ATC
cefalexin; oral
1.3
14.3
5034
47379
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
14.3
2124
18243
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
2.9
14.3
66
230
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
14.2
270
1633
B01AF02
ATC
apixaban; oral
1.5
14.1
482
3336
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
3.7
14.0
44
121
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
13.9
1571
13076
R01AD08
ATC
fluticasone; nasal
1.3
13.8
1649
13807
J01AA02
ATC
doxycycline; systemic
1.2
13.8
4661
43544
A99
ICPC
Disease/condition unspecnature/site
1.5
13.5
439
3007
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
13.5
13
*
24400
ICD-8 Finland
Myxoedema, (hypothyreosis) post therapiam
+∞
13.5
13
*
M14.5*E05.9
ICD-10 Finland
Arthropathy in thyrotoxicosis [hyperthyroidism]
+∞
13.5
13
*
R63.4
ICD-10 Finland
Abnormal weight loss
1.9
13.5
172
925
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
4.4
13.1
32
73
L28
ICPC
Limited function/disability (L)
1.3
12.9
785
6005
A02BC01
ATC
omeprazole; systemic
1.3
12.9
1384
11433
A02BC05
ATC
esomeprazole; systemic
1.2
12.7
2229
19420
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
3.8
12.7
38
101
6481B
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Thyroid dysfunction[HYPOTHYREOSIS IN GRAVIDITATE]
70.0
12.6
14
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
12.6
249
1524
Z01.7
ICD-10 Finland
Laboratory examination
1.4
12.5
742
5654
N07BA03
ATC
varenicline; oral
1.7
12.4
251
1543
XF404
NOMESCO Finland
Ambulatory ECG
1.5
12.3
381
2587
K02.1
ICD-10 Finland
Caries of dentine
1.2
12.1
3462
31572
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
12.1
949
7527
F29
ICPC
Eye symptom/complaint other
1.4
12.1
486
3472
2504
FHL
Unilateral resection or enucleation
11.0
12.0
22
20
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
5.0
11.9
25
50
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.4
11.8
504
3636
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
11.8
998
7990
N05BA04
ATC
oxazepam; oral
1.3
11.8
1389
11582
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.7
11.8
63
238
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.4
11.8
79
333
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
4.5
11.6
28
63
XF600
NOMESCO Finland
Bloodpressure measurement
1.6
11.6
266
1688
J01FA10
ATC
azithromycin; systemic
1.2
11.6
3486
31890
CS494
NOMESCO Finland
Other visual field testing
2.0
11.5
115
570
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
11.5
641
4837
E89
ICD-10 Finland
Postprocedural endocrine and metabolic disorders, not elsewhere classified
+∞
11.5
11
*
O992, E050,
ICD-10 Finland
+∞
11.5
11
*
GB1AA
NOMESCO Finland
Tracheal X-ray examination
120.2
11.4
12
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
11.4
2450
21715
R50.9
ICD-10 Finland
Fever, unspecified
1.3
11.4
695
5318
N06AX21
ATC
duloxetine; oral
1.4
11.3
620
4665
E04.8
ICD-10 Finland
Other specified nontoxic goitre
15.0
11.3
18
12
A09
ICPC
Sweating problem
2.5
11.3
67
267
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.7
11.3
191
1122
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
11.3
1220
10069
M03BX02
ATC
tizanidine; oral
1.2
11.2
3739
34469
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.5
11.2
337
2274
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
11.2
343
2324
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
11.2
581
4335
R25.1
ICD-10 Finland
Tremor, unspecified
1.9
11.1
134
709
R49.08
ICD-10 Finland
Other specified dysphonia
2.0
11.1
117
591
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
11.1
775
6045
W84
ICPC
Pregnancy high risk
1.7
11.0
182
1061
I48.1
ICD-10 Finland
Persistent atrial fibrillation
1.9
11.0
135
719
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
11.0
931
7454
TFP34
NOMESCO Finland
Electrophysiological investigation
1.9
11.0
138
741
D01
ICPC
Abdominal pain/cramps general
1.4
11.0
620
4688
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
3.1
11.0
44
142
C03DA01
ATC
spironolactone; oral
1.4
10.9
456
3278
N02AX02
ATC
tramadol; systemic, rectal
1.2
10.9
2193
19300
R02
ICPC
Shortness of breath/dyspnoea
1.4
10.9
596
4486
N05CF02
ATC
zolpidem; oral
1.3
10.8
942
7566
G47.3
ICD-10 Finland
Sleep apnoea
1.3
10.8
964
7768
BEF00, ,
SPAT
4.2
10.8
28
67
J01CA04
ATC
amoxicillin; systemic
1.2
10.7
5021
47691
A29
ICPC
General symptom/complaint other
1.4
10.7
573
4298
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
10.6
1087
8903
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
10.6
1423
12016
B01AB05
ATC
enoxaparin; parenteral
1.2
10.5
1587
13564
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
10.4
573
4313
H03BB02
ATC
thiamazole; oral
110.2
10.4
11
*
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
10.4
10
*
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
10.4
10
*
C01BC04
ATC
flecainide; systemic
1.8
10.4
140
770
R60.9
ICD-10 Finland
Oedema, unspecified
1.6
10.3
247
1588
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
18.8
10.2
15
8
SPAT1301
SPAT
No procedures
1.2
10.2
1547
13220
M54.5
ICD-10 Finland
Low back pain
1.2
10.1
2013
17664
WZC30
NOMESCO Finland
Teaching
1.3
10.1
728
5701
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
10.1
1096
9036
K78
ICPC
Atrial fibrillation/flutter
1.6
10.1
253
1642
N06AX11
ATC
mirtazapine; oral
1.2
10.0
1805
15691
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
2.8
10.0
48
172
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
3.0
10.0
43
145
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.6
9.9
208
1293
CKC12
NOMESCO Finland
Photocoagulation of retina
1.7
9.9
174
1033
R06AE07
ATC
cetirizine; oral
1.2
9.9
2618
23551
I47.2
ICD-10 Finland
Ventricular tachycardia
2.3
9.8
71
310
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.2
9.8
1629
14047
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
9.8
367
2589
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.0
9.8
102
515
Z71.8
ICD-10 Finland
Other specified counselling
1.2
9.7
1702
14750
SGA01
NOMESCO Finland
Emergency treatment
1.3
9.7
874
7047
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
9.6
1330
11259
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
9.5
2239
19919
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
9.5
658
5124
H50.52
ICD-10 Finland
Exophoria
2.4
9.4
64
272
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
30.0
9.4
12
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
30.0
9.4
12
*
E23.05
ICD-10 Finland
Lack of TSH
17.5
9.4
14
8
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
9.4
9
*
4CJ01, ,
NOMESCO Finland
+∞
9.4
9
*
E05.8
ICD-10 Finland
Other thyrotoxicosis
+∞
9.4
9
*
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
1.8
9.3
129
715
J01FA09
ATC
clarithromycin; systemic
1.2
9.3
1744
15195
EP1AE, ,
SPAT
1.9
9.3
104
539
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
9.3
2705
24494
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
9.2
2275
20304
C10AA07
ATC
rosuvastatin; oral
1.2
9.2
1454
12459
E83.50
ICD-10 Finland
Hypercalcemia
2.3
9.2
64
275
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
9.2
1035
8560
WX290
NOMESCO Finland
Other blockage of nerve
1.2
9.2
2698
24432
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
3.5
9.2
31
90
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
9.1
1907
16779
-60
ICPC
Result test/procedure
1.5
9.0
265
1782
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
1.8
9.0
131
738
R05
ICPC
Cough
1.2
9.0
1278
10836
D06
ICPC
Abdominal pain localized other
1.4
9.0
457
3400
T99
ICPC
Endocr/metab/nutrit disease other
2.2
8.9
70
317
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
18.6
8.9
13
7
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.6
8.9
181
1118
R60.0
ICD-10 Finland
Localized oedema
1.3
8.9
540
4125
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
2.4
8.8
56
231
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
8.8
4329
40814
J02AC01
ATC
fluconazole; systemic
1.2
8.8
2586
23401
I50.0
ICD-10 Finland
Congestive heart failure
1.6
8.7
210
1351
J01FA06
ATC
roxithromycin; oral
1.2
8.7
2187
19525
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.3
8.7
525
4007
G44.2
ICD-10 Finland
Tension-type headache
1.3
8.7
756
6066
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
50.1
8.7
10
*
D11
ICPC
Diarrhoea
1.3
8.6
614
4803
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
2.8
8.6
41
147
R51.80
ICD-10 Finland
Headache
1.3
8.6
826
6710
R11
ICD-10 Finland
Nausea and vomiting
1.4
8.5
412
3038
J45.9
ICD-10 Finland
Asthma, unspecified
1.2
8.5
942
7772
R21
ICPC
Throat symptom/complaint
1.2
8.5
1185
10021
A06AC01
ATC
ispaghula (psylla seeds); oral
1.2
8.5
1301
11105
M79.6
ICD-10 Finland
Pain in limb
1.2
8.5
2320
20847
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.0
8.5
84
417
R42
ICD-10 Finland
Dizziness and giddiness
1.2
8.5
1090
9142
XF402
NOMESCO Finland
ECG with work load test
1.4
8.5
405
2982
H36.01
ICD-10 Finland
Diabetic maculopathy
2.5
8.4
52
212
2506
FHL
Thyroidectomy
90.2
8.4
9
*
T71
ICPC
Malignant neoplasm thyroid
90.2
8.4
9
*
AQ2
HP
Electrophysiological electroanatomical examination
3.9
8.4
24
62
CE2W4
NOMESCO Finland
Eye movement mapping
6.7
8.3
20
30
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
8.3
2974
27281
2441A
ICD-9 Finland
Acquired hypothyroidism, Other postablative hypothyroidism
+∞
8.3
8
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
8.3
8
*
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
8.3
8
*
3762A
ICD-9 Finland
Disorders of the orbit, Endocrine exophthalmos
+∞
8.3
8
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.4
8.3
347
2498
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
8.2
646
5119
H02AA02
ATC
fludrocortisone; oral
3.0
8.2
35
118
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
8.2
1872
16568
C10AX09
ATC
ezetimibe; oral
1.3
8.2
593
4648
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.7
8.1
155
943
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
33.4
8.1
10
*
A98
ICPC
Health maint/preventive medicine
1.4
8.1
6260
61444
A02BC03
ATC
lansoprazole; oral
1.2
8.0
1411
12196
H02AB04
ATC
methylprednisolone; systemic
1.3
8.0
703
5643
SPAT1310
SPAT
Counselling related to known health issue
1.2
8.0
1592
13912
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
8.0
2029
18099
R01AD09
ATC
mometasone; nasal
1.2
8.0
2663
24269
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
8.0
641
5088
C10AA05
ATC
atorvastatin; oral
1.2
8.0
1739
15317
A91
ICPC
Abnormal result investigation NOS
1.5
8.0
206
1348
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
8.0
1392
12022
M25.5
ICD-10 Finland
Pain in joint
1.2
7.9
1796
15875
N03AX12
ATC
[U] gabapentin; oral
1.3
7.9
787
6418
S06.0
ICD-10 Finland
Concussion
1.3
7.8
487
3734
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.5
7.8
218
1451
H57.1
ICD-10 Finland
Ocular pain
1.6
7.8
189
1219
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
1.9
7.8
99
536
A50
ICPC
General and Unspecified, Medication/prescr/renewal
1.6
7.8
161
1001
J01FF01
ATC
clindamycin; systemic
1.2
7.8
1353
11681
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
1.7
7.8
142
855
L04
ICPC
Chest symptom/complaint
1.4
7.8
291
2055
R03BB04
ATC
tiotropium bromide; inhalant
1.4
7.8
371
2733
SPAT1312
SPAT
General health counselling
1.2
7.8
1622
14234
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
2.6
7.7
44
173
E06.5
ICD-10 Finland
Other chronic thyroiditis
45.0
7.7
9
*
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
2.3
7.6
55
241
L17
ICPC
Foot/toe symptom/complaint
1.2
7.6
1445
12567
SPAT1283
SPAT
Restricted health certificate
1.2
7.6
1000
8398
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.3
7.6
427
3225
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.3
7.6
628
5003
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
7.6
2936
27025
SFA20
NOMESCO Finland
Two-surface restoration
1.2
7.6
3412
31755
H05.0
ICD-10 Finland
Acute inflammation of orbit
8.0
7.6
16
20
R07.0
ICD-10 Finland
Pain in throat
1.4
7.5
350
2566
E66.8
ICD-10 Finland
Other obesity
1.4
7.5
276
1942
L03
ICPC
Low back symptom/complaint
1.2
7.5
1483
12948
F01
ICPC
Eye pain
1.7
7.4
140
850
AA1AD
NOMESCO Finland
CT of head and brain
1.2
7.4
1145
9768
2440A
ICD-9 Finland
Acquired hypothyroidism, Postsurgical hypothyroidism
80.2
7.4
8
*
T08
ICPC
Weight loss
2.1
7.4
69
336
S01GX01
ATC
cromoglicic acid; ophthalmic
1.2
7.4
1143
9755
H01.0
ICD-10 Finland
Blepharitis
1.4
7.4
335
2449
R74
ICPC
Upper respiratory infection acute
1.2
7.3
1881
16771
J01DA01
ATC
[U] cefalexin
1.2
7.3
3543
33105
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.4
7.3
312
2258
R07.3
ICD-10 Finland
Other chest pain
1.3
7.3
454
3485
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
7.3
1427
12446
R4110, ,
SPAT
1.4
7.3
394
2963
SFA30
NOMESCO Finland
Three-surface restoration
1.2
7.2
2283
20679
P06
ICPC
Sleep disturbance
1.3
7.2
574
4554
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
3.7
7.2
22
60
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.4
7.2
295
2120
N03AX16
ATC
[U] pregabalin
1.2
7.2
1127
9634
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
20.0
7.1
10
5
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
7.1
2785
25618
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.3
7.1
625
5021
L13.0
ICD-10 Finland
Dermatitis herpetiformis
3.3
7.1
26
80
R03BA05
ATC
fluticasone; inhalant
1.2
7.1
921
7727
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
7.1
643
5185
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
7.0
1388
12105
M01AH01
ATC
celecoxib; oral
1.2
7.0
869
7251
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
2.6
7.0
38
146
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
1.6
6.9
141
874
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
6.9
415
3168
XCH00
NOMESCO Finland
Eye pressure measurement
1.5
6.9
197
1322
C07AB03
ATC
atenolol; systemic
1.5
6.8
199
1339
Z50.5
ICD-10 Finland
Speech therapy
2.2
6.8
53
241
D64.9
ICD-10 Finland
Anaemia, unspecified
1.3
6.8
379
2863
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.3
6.8
598
4806
L13
ICPC
Hip symptom/complaint
1.2
6.8
879
7372
A97
ICPC
No disease
1.2
6.8
824
6865
-34
ICPC
Blood test
1.6
6.7
129
788
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
2.2
6.7
52
236
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.4
6.7
279
2012
E50.9
ICD-10 Finland
Vitamin A deficiency, unspecified
22.5
6.7
9
*
C01DA14
ATC
isosorbide mononitrate; oral
1.3
6.6
434
3354
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
6.6
1486
13093
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
4.0
6.6
18
45
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
6.6
613
4956
SPAT1281
SPAT
Other administrative function
1.4
6.6
337
2512
D09
ICPC
Nausea
1.5
6.6
212
1457
E66.01
ICD-10 Finland
Obesity due to excess calories
1.3
6.6
442
3429
D07AD01
ATC
clobetasol; topical
1.2
6.6
816
6810
N17
ICPC
Vertigo/dizziness
1.3
6.6
537
4276
R03DC03
ATC
montelukast; oral
1.2
6.6
884
7441
A08
ICPC
Swelling
1.5
6.5
208
1427
E0000UV, ,
ATC
1.2
6.5
2263
20604
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
6.5
1675
14923
C10AA03
ATC
pravastatin; oral
1.4
6.5
242
1712
EB1VA, ,
NOMESCO Finland
1.3
6.5
611
4951
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
6.4
1334
11673
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
5.7
6.4
17
30
AN1
HP
Coronary angiography
1.4
6.4
319
2367
Z00.8
ICD-10 Finland
Other general examinations
1.3
6.4
350
2637
SPAT1377
SPAT
Polysomnography
1.6
6.4
136
854
K77
ICPC
Heart failure
2.0
6.4
65
328
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
1.6
6.4
145
925
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
6.4
806
6740
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
2.0
6.4
61
301
C08CA01
ATC
amlodipine; oral
1.2
6.3
1611
14328
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
1.7
6.3
101
588
342
Kela drug reimbursment
Dronedarone
2.7
6.3
32
119
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.5
6.3
160
1048
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
3.5
6.3
21
61
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
1.4
6.3
219
1530
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.4
6.3
267
1933
H060, E050,
ICD-10 Finland
+∞
6.2
6
*
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
6.2
6
*
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
6.2
6
*
BA1MN
NOMESCO Finland
Thyroid gland isotope imaging with calculation
+∞
6.2
6
*
BA1AN
NOMESCO Finland
Thyroid gland isotope imaging
+∞
6.2
6
*
E8901, E050,
ICD-10 Finland
+∞
6.2
6
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.3
6.2
404
3119
TFP35
NOMESCO Finland
Electroanatomical mapping
2.0
6.2
59
290
M48.0
ICD-10 Finland
Spinal stenosis
1.3
6.2
464
3651
BAA99
NOMESCO Finland
Other operation on thyroid gland
26.7
6.2
8
*
P03
ICPC
Feeling depressed
1.3
6.2
493
3912
A01
ICPC
Pain general/multiple sites
1.3
6.2
419
3255
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.2
6.2
699
5777
UJF30
NOMESCO Finland
Ileoscopy through colon
1.3
6.2
463
3646
R13
ICD-10 Finland
Dysphagia
1.4
6.2
262
1896
R96
ICPC
Asthma
1.3
6.2
450
3532
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.2
6.1
688
5680
C01BD07
ATC
dronedarone; oral
2.8
6.1
29
104
R01AD12
ATC
fluticasone furoate; nasal
1.2
6.1
1799
16166
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
2.3
6.1
45
200
A63.0
ICD-10 Finland
Anogenital (venereal) warts
1.5
6.1
184
1249
-50
ICPC
Medication/prescr/renewal
1.5
6.1
162
1071
SFA10
NOMESCO Finland
One-surface restoration
1.1
6.1
3100
28914
SPAT1254
SPAT
Administration of medicine
1.3
6.1
601
4893
L50
ICD-10 Finland
Urticaria
1.8
6.1
89
506
E66.9
ICD-10 Finland
Obesity, unspecified
1.5
6.1
163
1080
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.2
6.1
604
4923
EBA00
NOMESCO Finland
Extraction of tooth
1.2
6.0
1781
16008
Z3229
NOMESCO Finland
Other healthcare associate professional
1.3
6.0
333
2513
SPAT1260
SPAT
Consultation of another employee
1.2
6.0
801
6730
M79.7
ICD-10 Finland
Fibromyalgia
1.5
6.0
188
1285
S01XA18
ATC
ciclosporin; ophthalmic
2.4
6.0
40
170
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.2
6.0
924
7872
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3538
1819
41.19
307.65
7.6
1.5
4.81
4.45
pmol/l
25.38
3328
1602
1822
2935
8.22
307.65
1.4
1.1
225.01
75.19
iu/ml
32.18
1000
964
6225
41880
11.07
307.65
14.1
2.5
15.62
14.30
pmol/l
271.74
6025
38265
3153
556
108.55
307.65
3.2
1.1
22.00
2.01
iu/l
1.20
2056
112
6296
50380
7.67
287.02
15.3
3.3
1.71
1.99
mu/l
3.34
6074
46586
3782
24046
2.36
242.84
7.1
5.9
1.22
1.22
mmol/l
1.65
3213
20414
967
3285
3.28
222.50
3.1
3.5
62.11
86.97
ng/l
16.39
862
2839
3408
21621
2.20
207.91
6.1
5.3
1.22
1.22
mmol/l
0.54
3157
19755
150
89
17.23
181.64
1.6
1.2
16.00
13.73
pmol/l
3.01
134
73
4271
30697
2.13
175.74
9.4
8.9
3.77
4.00
e9/l
10.75
3769
26834
193
186
10.66
175.63
3.8
1.1
145.43
129.76
u/ml
0.07
72
28
5081
40258
2.17
145.54
8.4
7.1
78.57
76.23
u/l
3.99
4861
37949
2659
17017
1.95
140.55
3.0
3.3
2.34
2.36
mmol/l
16.06
2394
15071
3215
22613
1.83
120.62
2.5
2.2
75.82
77.04
nmol/l
1.78
2933
20650
4889
39981
1.88
103.36
4.3
3.9
11.55
11.53
mm/h
0.03
4606
37258
6075
54998
2.47
79.04
15.8
13.1
139.70
139.68
mmol/l
0.41
5955
53583
6086
55179
2.48
78.25
16.1
13.2
3.94
3.93
mmol/l
0.17
5955
53638
1921
12777
1.71
78.08
1.4
1.3
1.83
1.51
u/ml
0.49
525
3485
850
4471
2.04
72.70
2.1
2.0
374.53
375.97
nmol/l
0.08
779
4107
3298
25686
1.57
67.99
5.7
6.0
28.76
28.70
%
0.12
3092
24160
3476
27446
1.57
67.12
5.7
6.0
0.19
0.18
e9/l
0.78
3106
24219
3108
23956
1.57
66.51
5.7
6.0
0.67
0.69
%
0.79
2891
22348
3251
25345
1.56
65.93
5.5
5.7
56.35
56.90
%
1.89
3041
23812
3191
24801
1.56
65.40
5.7
5.9
2.85
2.79
%
0.68
2983
23221
3200
24926
1.56
64.66
5.9
6.2
8.51
8.28
%
3.91
2985
23390
3431
27258
1.54
62.59
5.5
5.8
1.86
1.93
e9/l
3.18
3103
24253
3342
26494
1.53
60.87
5.5
5.8
0.04
0.04
e9/l
3.47
2943
22990
6248
58208
2.64
60.19
12.7
9.5
24.53
24.89
u/l
0.93
6119
56318
3329
26439
1.53
59.62
5.5
5.8
0.56
0.55
e9/l
0.12
2939
22976
5655
51009
1.80
56.57
13.5
11.0
85.22
84.72
ml/min/173m2
0.97
4834
41787
3140
24811
1.51
56.36
3.2
2.7
98.02
100.22
ug/l
0.24
2942
23272
3580
29151
1.50
55.01
4.6
4.2
6.61
6.51
mmol/l
1.91
3343
26974
5374
48094
1.66
51.58
5.7
4.8
39.47
38.63
mmol/mol
8.05
5006
44841
1578
10966
1.58
49.75
1.5
1.4
2.17
2.29
g/l
2.14
934
6754
286
1114
2.64
49.19
1.3
1.2
—
—
—
0
0
2940
23409
1.46
47.85
10.9
8.7
0.00
0.00
e9/l
1.21
2457
19009
918
5636
1.73
46.90
4.7
5.3
1.07
1.04
mmol/l
2.84
850
5257
5931
54882
1.87
46.37
14.2
12.1
19.51
21.85
mg/l
6.65
4754
42572
2510
19729
1.44
41.92
2.0
1.9
97.44
97.82
pmol/l
0.13
1286
9937
5670
52118
1.66
41.22
4.5
4.0
5.84
5.77
mmol/l
4.08
5237
48065
5293
48035
1.53
38.83
19.6
14.4
14.69
14.86
%
0.58
5227
47197
3188
26504
1.40
37.12
5.7
5.9
10.53
10.51
umol/l
0.03
3021
25085
1636
12199
1.45
34.75
2.3
2.2
2.81
2.86
mg/l
0.38
1419
10488
2643
21452
1.39
34.70
4.3
4.5
35.89
35.97
g/l
0.30
2439
19961
1591
11809
1.46
34.60
3.3
2.7
1205.16
1119.36
ng/l
0.40
1358
10017
645
3896
1.73
34.34
3.8
3.4
1.23
1.23
mmol/l
3.03
569
3418
1086
7495
1.54
33.62
3.1
3.3
0.81
0.82
mmol/l
1.23
1021
7055
2633
21438
1.38
33.56
14.5
11.8
1.25
1.18
inr
3.15
889
6362
2209
17724
1.37
29.81
3.6
3.1
71.04
70.38
ng/l
0.00
1317
10508
6371
61542
2.36
27.79
25.0
17.8
40.27
39.98
%
1.55
6068
57990
1027
7278
1.49
27.51
2.5
2.3
13.44
13.46
umol/l
0.03
941
6796
950
6651
1.50
26.97
2.4
2.3
2.43
2.39
g/l
1.16
867
6169
6373
61617
2.34
26.91
25.0
17.8
261.91
261.25
e9/l
0.38
6282
60152
6375
61665
2.33
26.53
25.0
17.8
6.51
6.62
e9/l
3.78
6261
60041
6375
61665
2.33
26.53
25.0
17.8
4.51
4.46
e12/l
20.06
6258
60072
6376
61685
2.33
26.41
25.1
17.9
134.84
133.81
g/l
9.21
6331
60922
203
913
2.26
25.54
1.9
1.8
4.92
5.23
mmol/24h
0.69
174
812
1790
14254
1.35
24.20
2.1
2.0
197.75
187.02
u/l
0.09
1683
13391
1212
9056
1.42
24.19
2.7
2.8
2.44
2.45
mmol/l
2.25
1038
7940
1964
15877
1.34
23.96
2.4
2.4
66.80
63.67
u/l
0.09
1807
14666
1066
7880
1.42
22.44
1.4
1.4
562.48
541.43
titre
0.14
258
1656
866
6163
1.47
22.35
2.6
2.4
22.23
22.87
%
0.74
735
5260
5691
53772
1.45
21.74
4.4
3.9
4.74
4.84
mmol/l
10.61
5316
50343
5757
54588
1.46
20.85
4.8
4.3
2.83
2.88
mmol/l
3.86
5351
50808
2943
25486
1.28
20.67
2.4
2.4
—
—
—
0
0
1325
10303
1.36
20.35
1.3
1.3
27.65
30.07
iu/ml
0.30
410
3439
4108
37161
1.28
19.97
3.1
2.9
41.72
41.63
u/l
0.02
3895
34919
1579
12649
1.33
19.77
2.1
2.1
—
—
—
0
0
1515
12078
1.33
19.59
2.1
1.7
0.95
1.05
mg/l
0.98
1139
9125
1181
9093
1.36
19.19
3.8
3.3
237.08
373.19
ng/l
1.18
834
6306
5642
53452
1.40
19.11
4.4
3.9
1.51
1.55
mmol/l
9.74
5254
49852
1070
8115
1.38
19.10
1.7
1.7
1104.74
1187.46
nmol/l
2.41
843
6203
5457
51425
1.37
19.03
3.9
3.5
1.24
1.24
mmol/l
0.01
5057
47650
1254
9809
1.34
18.28
1.3
1.3
7.41
11.27
u/ml
1.61
469
4011
1635
13342
1.30
17.55
4.1
3.7
8.56
8.93
mg/mmol
0.13
1005
8050
1346
10712
1.32
17.31
1.5
1.5
20.45
21.11
nmol/l
0.94
1174
9177
1559
12708
1.30
16.74
3.5
3.1
577.38
415.45
mg/l
0.53
979
7662
166
818
2.06
16.69
1.2
1.3
—
—
—
0
0
1707
14100
1.29
16.50
3.3
3.1
7.09
7.21
mmol/l
0.51
1443
12020
2079
17659
1.26
15.83
3.1
3.1
29.12
32.37
u/l
2.26
1981
16781
414
2723
1.56
15.44
1.2
1.1
167.56
219.08
titre
0.25
18
71
1261
10106
1.31
15.17
1.7
1.6
51928938.68
37507755.66
pmol/l
0.34
1063
8545
641
4630
1.43
15.01
2.6
2.5
1.66
1.78
%
2.42
582
4121
362
2340
1.58
14.57
1.1
1.1
1.88
1.89
u/ml
—
6
28
118
553
2.15
13.61
1.2
1.2
81.05
58.03
u/l
2.31
106
502
1250
10155
1.29
13.37
2.7
2.4
7.16
7.04
e6/l
0.09
1119
9030
494
3487
1.45
13.08
2.1
2.5
65.79
66.79
g/l
2.25
455
3195
3892
35783
1.22
12.94
4.8
4.2
1653.42
2363.35
e6/l
0.33
65
424
263
1630
1.64
12.62
1.3
1.3
42.81
47.45
u/ml
0.09
20
111
930
7348
1.31
12.19
1.8
1.8
—
—
—
0
0
1724
14692
1.24
12.04
3.5
3.0
51.14
74.95
e6/l
0.40
1330
10984
2051
17838
1.22
11.68
4.0
3.4
83.88
105.23
e6/l
0.85
1434
11997
510
3699
1.41
11.62
3.7
3.8
2.04
2.01
mmol/l
0.05
415
3162
510
3706
1.41
11.50
3.7
3.7
5.90
5.84
kpa
0.71
490
3612
495
3589
1.41
11.30
3.3
2.7
213.75
163.76
ng/l
0.71
443
3248
65
257
2.54
11.11
1.2
1.1
13.48
21.39
u/l
1.70
59
233
514
3766
1.40
11.04
1.4
1.3
30.02
30.83
iu/l
0.22
449
3303
1530
12997
1.23
10.82
3.9
3.6
92.01
94.50
%
3.44
1488
12660
64
258
2.50
10.53
1.2
1.1
68.15
78.93
u/l
1.00
59
235
629
4804
1.34
10.40
3.2
3.1
—
—
—
0
0
1492
12688
1.23
10.38
2.5
2.3
4085.07
4004.98
umol/l
0.02
1308
11243
533
3978
1.37
10.24
3.6
4.2
0.06
0.12
%
1.64
138
1148
232
1472
1.60
10.19
1.3
1.3
11.67
6.54
u/ml
0.21
22
147
1573
13480
1.22
10.11
3.4
2.9
0.33
0.42
e6/l
1.52
1197
9993
234
1491
1.59
10.10
1.3
1.3
28.04
6.38
u/ml
0.99
31
244
69
294
2.36
10.09
1.1
1.1
2.77
9.93
nmol/l
0.57
12
55
466
3414
1.39
10.02
2.2
2.5
71.16
70.76
e9/l
0.07
355
2508
66
277
2.40
9.98
2.2
1.8
18.27
19.96
nmol/l
0.85
61
264
295
1987
1.51
9.93
2.0
2.0
—
—
—
0
0
2918
26510
1.18
9.78
3.7
3.5
0.00
0.00
estimate
1.98
626
5148
1596
13745
1.21
9.69
1.7
1.6
1.32
1.35
mmol/l
0.81
1318
11719
255
1682
1.54
9.48
1.1
1.1
5.53
6.77
u/ml
0.23
41
225
251
1651
1.54
9.45
1.6
1.8
0.23
0.23
g/l
0.59
233
1568
2915
26573
1.17
9.15
5.1
4.7
0.00
0.00
estimate
1.60
611
4889
255
1696
1.52
9.13
1.6
1.8
1.19
1.18
g/l
0.17
235
1615
503
3802
1.35
8.91
3.4
4.0
0.77
0.65
%
0.50
138
1158
2936
26817
1.17
8.91
3.8
3.5
0.00
0.00
estimate
0.24
593
4845
127
712
1.80
8.89
3.8
3.0
0.77
0.82
nmol/l
0.85
109
538
242
1604
1.53
8.82
1.8
1.6
331.11
254.67
titre
0.20
18
75
885
7230
1.26
8.75
2.0
2.3
124.06
112.38
ug/g
0.34
689
5744
340
2419
1.43
8.67
2.9
3.4
2.04
1.86
mmol/l
0.34
245
1804
506
3852
1.34
8.55
2.5
2.7
10.19
10.41
g/l
0.62
459
3555
197
1258
1.58
8.48
1.3
1.2
46.81
44.05
u/ml
0.09
24
140
29
85
3.42
8.47
1.3
1.3
73.39
98.62
ng/l
1.16
29
85
352
2560
1.40
7.95
3.0
3.4
5.23
5.17
kpa
0.59
334
2432
262
1812
1.46
7.81
1.8
1.8
—
—
—
0
0
70
339
2.08
7.61
1.5
1.6
6.07
6.36
u/l
0.07
55
285
26
77
3.39
7.51
1.5
1.5
—
—
—
0
0
723
5889
1.26
7.30
2.8
2.6
6.90
7.30
umol/l
0.24
629
5016
10
5
20.03
7.13
1.4
1.0
—
—
—
0
0
461
3558
1.32
7.11
8.1
7.0
9.53
8.78
mmol/l
1.56
439
3413
183
1202
1.54
7.03
1.3
1.2
0.97
2.58
u/ml
1.18
14
90
609
4893
1.27
6.90
4.6
4.1
234.56
243.41
u/l
0.98
575
4617
250
1758
1.44
6.87
1.9
1.9
—
—
—
0
0
144
900
1.61
6.86
2.1
2.2
5.39
6.07
umol/l
0.31
97
664
206
1399
1.49
6.78
1.4
1.3
11.39
12.49
u/l
0.50
171
1153
303
2211
1.39
6.75
2.1
2.0
40.62
39.57
u/l
0.38
274
1990
321
2367
1.37
6.72
1.3
1.3
0.92
1.24
u/ml
0.27
29
223
471
3714
1.29
6.22
6.9
6.7
1.27
1.30
mmol/l
0.23
458
3627
441
3453
1.30
6.15
2.2
2.2
8.41
6.19
ug/l
0.74
373
2985
223
1576
1.43
6.01
3.0
3.7
24.96
24.95
mmol/l
0.01
203
1450
400
3118
1.30
5.78
1.0
1.1
—
—
—
0
0
200
1396
1.45
5.78
2.2
2.1
10.81
11.29
mg/l
0.39
188
1307
134
864
1.56
5.68
1.1
1.0
2.83
3.23
u/ml
0.18
66
432
437
3457
1.28
5.65
1.7
1.6
—
—
—
0
0
211
1497
1.42
5.59
1.3
1.2
107.00
139.53
titre
0.35
20
148
885
7561
1.20
5.59
3.1
2.6
3.88
3.73
e6/l
0.14
497
3852
306
2310
1.34
5.56
2.8
2.5
0.21
0.25
e6/l
0.30
295
2221
24
82
2.93
5.56
1.0
1.0
—
—
—
0
0
322
2456
1.33
5.46
3.6
3.2
131.42
128.33
g/l
1.81
314
2401
283
2118
1.35
5.45
1.6
1.5
278.68
293.95
mu/l
0.42
244
1904
389
3051
1.29
5.39
3.3
3.1
4.57
4.59
kpa
0.06
373
2963
115
725
1.60
5.38
1.2
1.3
0.29
0.30
nmol/l
—
9
49
1551
13906
1.15
5.35
4.1
3.9
0.00
0.00
estimate
1.98
599
4802
216
1555
1.40
5.29
2.0
2.3
2.97
2.93
g/l
0.26
200
1415
384
3023
1.29
5.18
1.9
1.9
1.18
1.35
g/l
1.88
355
2790
2223
20459
1.13
5.13
3.9
3.6
—
—
—
0
0
168
1164
1.45
5.10
2.0
2.3
0.00
0.00
g/l
0.50
158
1074
44
210
2.10
5.09
1.1
1.3
149.93
144.16
mmol/24h
0.23
44
210
183
1290
1.43
5.07
2.0
2.2
38.26
38.16
g/l
0.10
167
1148
166
1149
1.46
5.06
2.1
2.3
0.00
0.00
g/l
-0.00
158
1070
76
438
1.74
5.03
1.2
1.1
—
—
—
0
0
76
438
1.74
5.03
1.2
1.1
—
—
—
0
0
196
1401
1.41
5.02
2.2
2.4
0.32
0.82
g/l
1.91
174
1232
76
439
1.74
4.99
1.2
1.1
—
—
—
0
0
76
439
1.74
4.99
1.2
1.1
—
—
—
0
0
76
440
1.74
4.95
1.2
1.1
—
—
—
0
0
291
2222
1.32
4.93
9.1
8.9
24.47
24.33
mmol/l
0.31
285
2170
71
404
1.77
4.91
1.4
1.2
0.39
1.69
u/ml
2.02
41
226
91
556
1.65
4.87
3.0
3.0
3.50
14.86
nmol/l
0.60
86
538
4100
39190
1.12
4.86
3.3
3.2
—
—
—
0
0
177
1254
1.42
4.79
2.0
2.3
0.00
0.02
g/l
0.56
167
1160
222
1636
1.37
4.77
2.1
2.3
—
—
—
0
0
133
895
1.50
4.70
2.3
2.3
113.06
78.29
ug/min
0.43
84
523
222
1640
1.37
4.70
2.1
2.3
7.55
7.41
g/l
0.52
205
1499
221
1638
1.36
4.59
2.1
2.3
3.71
3.64
g/l
0.24
204
1496
518
4288
1.23
4.55
7.2
7.4
95.33
95.98
%
1.32
491
4117
207
1521
1.37
4.55
2.1
2.3
9.79
10.22
g/l
1.02
191
1373
70
408
1.72
4.49
1.2
1.2
115.40
49.35
u/ml
—
5
33
248
1880
1.33
4.45
3.4
3.1
25.59
25.42
mmol/l
0.34
237
1830
709
6064
1.19
4.42
4.5
4.0
33.26
32.88
%
0.43
512
4195
588
4951
1.21
4.35
1.7
1.7
—
—
—
0
0
197
1447
1.37
4.35
2.0
2.2
253.49
591.03
ug/l
1.43
181
1335
476
3929
1.23
4.31
2.3
2.3
20.67
24.61
au/ml
0.43
28
357
240
1823
1.33
4.27
2.3
2.0
10.27
11.19
nmol/l
0.76
217
1625
581
4904
1.20
4.20
6.9
6.9
1.11
1.10
mmol/l
0.02
457
3898
56
313
1.80
4.17
1.1
1.2
17.62
18.08
u/l
0.04
47
271
584
4936
1.20
4.16
1.7
1.7
—
—
—
0
0
539
4522
1.21
4.15
2.1
2.1
0.22
0.22
g/l
0.17
502
4247
581
4915
1.20
4.10
7.0
6.9
5.11
5.09
kpa
0.19
556
4686
75
458
1.64
4.09
1.1
1.3
—
—
titre
—
0
0
243
1863
1.32
4.07
1.9
1.7
1.46
1.55
g/l
0.77
208
1603
112
752
1.50
4.06
1.1
1.1
133.40
13437.03
iu/ml
0.55
26
180
580
4914
1.20
4.03
7.0
6.9
12.41
12.94
kpa
1.63
555
4683
575
4869
1.20
4.02
2.5
2.3
39.01
48.24
u/l
0.40
494
4155
149
1062
1.41
3.97
3.0
3.8
57.65
57.48
%
0.06
149
1062
97
635
1.54
3.96
1.3
1.5
—
—
—
0
0
97
635
1.54
3.96
1.3
1.5
—
—
—
0
0
24
99
2.43
3.96
1.6
1.2
66.04
59.24
mu/l
0.07
19
76
359
2906
1.25
3.92
2.1
2.1
5955.09
5272.72
u/l
0.16
150
1165
446
3707
1.22
3.80
1.4
1.3
152.84
187.29
u/ml
0.98
416
3423
96
634
1.52
3.79
1.3
1.5
—
—
—
0
0
56
323
1.74
3.79
1.1
1.2
69.57
80.27
u/l
0.48
47
286
15
50
3.00
3.68
8.3
11.1
5.11
4.87
mmol/l
0.14
15
50
171
1265
1.36
3.67
1.3
1.3
—
—
—
0
0
145
1044
1.40
3.67
1.6
1.6
—
—
—
0
0
29
135
2.15
3.66
1.2
1.7
0.49
0.36
ug/l
0.67
16
97
110
755
1.46
3.62
1.3
1.3
71.43
56.78
u/ml
—
8
61
96
641
1.51
3.62
1.3
1.5
—
—
—
0
0
96
642
1.50
3.59
1.3
1.5
—
—
—
0
0
10
310
0.32
3.54
19.4
12.6
715.10
858.05
nmol/l
—
10
296
97
654
1.49
3.50
1.3
1.5
—
—
—
0
0
697
6084
1.16
3.42
4.9
4.6
2.19
2.65
ug/l
1.08
611
5463
107
741
1.45
3.39
1.6
1.6
—
—
—
0
0
107
741
1.45
3.39
1.6
1.6
—
—
—
0
0
187
1423
1.32
3.36
1.5
1.4
278.55
287.03
ug/g
0.23
118
774
154
1140
1.36
3.33
1.3
1.4
—
—
—
0
0
322
2636
1.23
3.23
1.6
1.6
—
—
—
0
0
427
3601
1.20
3.18
1.3
1.3
71.71
50.97
au/ml
0.57
15
192
132
962
1.38
3.17
3.0
3.5
2.49
2.49
mmol/l
0.01
93
650
12
321
0.37
3.16
18.3
17.6
1126.75
4400.60
nmol/l
0.58
12
313
125
906
1.39
3.10
2.3
2.4
16.58
16.37
%
0.23
66
453
916
8207
1.14
3.10
2.9
2.5
1.28
1.35
e6/l
0.12
518
4473
43
245
1.76
3.09
1.7
1.6
2.19
4.96
nmol/l
0.75
35
196
21
92
2.29
3.09
1.8
2.0
6.86
6.94
mmol/l
0.03
13
56
138
1019
1.36
3.06
2.1
2.2
132.30
128.64
g/l
1.05
102
735
152
1148
1.33
2.93
1.3
1.3
27.91
29.41
u/l
0.21
124
951
152
1151
1.33
2.88
1.7
1.3
24.85
24.86
e6/l
0.00
122
875
152
1153
1.33
2.85
1.7
1.4
563.91
4397.05
e6/l
0.63
129
925
103
736
1.41
2.81
1.7
1.7
—
—
—
0
0
88
611
1.45
2.81
1.4
1.3
317.49
349.11
pmol/l
0.24
75
524
468
4029
1.17
2.78
7.9
7.7
121.37
120.59
g/l
0.35
451
3903
10
28
3.58
2.78
1.0
1.3
—
—
—
0
0
785
7027
1.13
2.71
2.6
2.1
30.15
29.47
s
2.08
752
6800
136
1026
1.33
2.67
1.6
1.6
—
—
—
0
0
1288
11875
1.11
2.64
1.6
1.6
—
—
—
0
0
152
1168
1.31
2.63
1.8
1.6
10498.19
11307.33
e6/l
0.09
109
848
83
579
1.44
2.61
2.2
2.0
25.27
26.57
mg/l
0.05
22
153
30
163
1.84
2.56
15.8
3.5
71.55
1362.22
mg/l
0.49
22
112
199
1589
1.26
2.56
1.2
1.2
—
—
—
0
0
55
355
1.55
2.52
1.2
1.3
—
—
—
0
0
98
712
1.38
2.47
3.0
3.4
0.95
1.39
%
1.49
86
651
37
217
1.71
2.47
1.6
1.4
—
—
—
0
0
37
217
1.71
2.47
1.6
1.4
—
—
—
0
0
43
263
1.64
2.46
1.1
1.1
—
—
—
0
0
73
504
1.45
2.45
1.5
1.7
—
—
—
0
0
40
242
1.66
2.40
1.6
1.8
—
—
—
0
0
59
393
1.51
2.37
1.2
1.2
101.00
226.71
titre
—
10
73
40
243
1.65
2.36
1.6
1.8
—
—
—
0
0
11
39
2.82
2.34
1.1
1.1
29.45
9.28
u/l
0.38
11
39
315
2668
1.19
2.32
1.6
1.5
—
—
—
0
0
6
13
4.62
2.27
1.0
1.2
3.00
2.85
%
—
6
13
211
1724
1.23
2.26
1.4
1.4
—
—
—
0
0
550
4876
1.14
2.24
4.0
4.0
23.70
21.30
%
2.27
229
2254
428
3735
1.16
2.19
1.4
1.5
—
—
—
0
0
56
376
1.49
2.19
1.6
1.6
—
—
—
0
0
56
376
1.49
2.19
1.6
1.6
—
—
—
0
0
56
376
1.49
2.19
1.6
1.6
—
—
—
0
0
161
1285
1.26
2.14
3.2
3.1
36.02
55.77
mg/l
2.00
121
1025
78
561
1.40
2.14
1.7
1.6
—
—
—
0
0
157
1250
1.26
2.13
3.2
3.0
1.32
1.50
ratio
—
9
106
161
1287
1.26
2.11
3.2
3.1
27.82
41.13
mg/l
1.77
121
1028
194
1584
1.23
2.11
2.3
2.0
1.80
1.95
ug/l
0.08
171
1401
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
164
1316
1.25
2.09
4.2
3.2
0.37
0.36
u/ml
0.07
86
743
36
221
1.63
2.08
1.3
1.8
1.81
1.94
umol/l
0.61
36
205
57
389
1.47
2.08
1.1
1.1
1.05
1.05
ratio
0.08
25
136
91
677
1.35
2.04
1.1
1.1
1.48
1.49
g/l
0.07
86
618
236
1973
1.20
2.04
1.7
1.7
—
—
—
0
0
0
58
0.00
2.03
0.0
1.1
—
—
—
0
0
66
466
1.42
2.02
1.6
1.7
—
—
—
0
0
44
286
1.54
2.02
1.5
1.3
—
—
—
0
0
74
534
1.39
2.01
1.3
1.4
—
—
—
0
0
129
1011
1.28
2.01
1.2
1.3
2.37
3.75
ug/l
2.44
112
890
136
1073
1.27
2.01
1.2
1.2
—
—
—
0
0
21
111
1.89
2.00
1.1
1.1
360.43
302.24
pmol/l
0.15
14
80
123
961
1.29
1.97
6.3
5.5
313.17
925.43
iu/ml
0.94
18
121
43
280
1.54
1.97
1.5
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
43
280
1.54
1.97
1.2
1.1
—
—
—
0
0
65
461
1.41
1.95
1.4
1.4
278.79
276.80
mosm/kgh2o
0.25
48
351
22
120
1.84
1.92
1.0
1.1
—
—
—
0
0
405
3559
1.15
1.92
2.8
2.9
0.74
0.73
ug/l
0.04
257
2280
73
531
1.38
1.91
1.1
1.0
—
—
—
0
0
35
219
1.60
1.90
1.6
2.4
152.56
149.45
umol/l
0.02
18
121
61
432
1.42
1.86
3.2
3.5
53.58
55.78
%
0.31
53
381
79
585
1.35
1.86
1.6
1.6
53.44
55.75
%
0.20
55
364
18
93
1.94
1.84
1.2
1.1
—
—
—
0
0
46
309
1.49
1.84
1.7
1.5
6.26
5.26
u/l
0.53
36
261
124
981
1.27
1.82
1.4
1.4
145.14
114.50
u/ml
0.45
38
207
161
1314
1.23
1.81
1.5
1.3
469.41
485.52
mg/l
0.23
150
1247
291
2511
1.17
1.78
1.4
1.4
—
—
—
0
0
80
598
1.34
1.78
1.5
1.5
—
—
—
0
0
52
361
1.44
1.78
1.2
1.1
—
—
—
0
0
324
2830
1.15
1.70
1.4
1.4
—
—
—
0
0
14
68
2.06
1.70
1.1
1.1
—
—
—
0
0
68
501
1.36
1.68
1.6
1.5
—
—
—
0
0
68
501
1.36
1.68
1.6
1.5
—
—
—
0
0
48
333
1.44
1.67
1.0
1.1
—
—
—
0
0
118
941
1.26
1.65
1.6
1.6
—
—
—
0
0
31
196
1.58
1.65
1.7
1.9
—
—
—
0
0
31
196
1.58
1.65
1.7
1.9
—
—
—
0
0
15
76
1.98
1.64
1.1
1.4
—
—
—
0
0
111
880
1.27
1.64
1.1
1.1
—
—
—
0
0
54
386
1.40
1.61
1.1
1.2
—
—
—
0
0
43
295
1.46
1.59
1.6
1.5
35.40
20.59
u/ml
—
5
63
30
190
1.58
1.59
1.0
1.1
1982.00
976.66
ng/l
—
5
38
74
558
1.33
1.59
1.8
1.7
89.63
90.01
%
0.17
74
547
31
198
1.57
1.59
1.7
1.9
—
—
—
0
0
28
175
1.60
1.57
1.1
1.2
—
—
—
0
0
54
388
1.40
1.57
1.1
1.2
—
—
—
0
0
108
862
1.26
1.53
1.7
1.6
—
—
—
0
0
35
233
1.50
1.51
1.2
1.2
—
—
—
0
0
104
828
1.26
1.50
2.2
3.0
30.23
32.96
umol/l
0.86
88
754
45
317
1.42
1.47
1.3
1.2
—
—
—
0
0
63
470
1.34
1.47
1.7
1.7
—
—
—
0
0
160
1338
1.20
1.47
2.1
1.6
—
—
—
0
0
54
394
1.37
1.45
1.4
1.3
2.02
2.00
mmol/l
0.07
49
370
6
22
2.73
1.43
1.0
1.0
—
—
—
0
0
76
587
1.30
1.41
1.1
1.1
—
3.04
—
0
5
67
510
1.32
1.39
13.4
4.4
7.68
7.45
mmol/l
0.15
56
426
57
424
1.35
1.38
1.7
1.7
—
—
—
0
0
134
1110
1.21
1.37
1.5
1.4
0.45
0.44
nmol/l
0.07
101
860
39
272
1.44
1.36
2.3
1.5
—
—
—
0
0
17
97
1.75
1.34
1.9
1.3
—
—
—
0
0
26
167
1.56
1.34
1.7
1.4
—
—
—
0
0
96
772
1.25
1.31
1.4
1.5
—
—
—
0
0
182
2118
0.86
1.30
2.0
2.0
—
—
—
0
0
207
1793
1.16
1.29
1.3
1.3
—
—
—
0
0
123
1021
1.21
1.26
1.2
1.2
274.63
278.63
u/ml
0.06
78
654
137
1150
1.20
1.25
1.4
1.2
3.84
3.65
mmol/l
1.12
131
1086
64
497
1.29
1.18
1.3
1.3
—
—
—
0
0
28
189
1.48
1.18
1.1
1.2
115.43
110.50
%
0.42
23
170
183
1584
1.16
1.17
1.2
1.1
—
—
—
0
0
81
649
1.25
1.17
1.3
1.4
—
—
—
0
0
30
206
1.46
1.17
1.2
1.2
0.31
0.30
g/l
0.33
25
165
147
1251
1.18
1.17
1.6
1.4
—
—
—
0
0
295
2639
1.12
1.16
9.5
8.7
0.63
0.69
%
2.04
295
2623
70
552
1.27
1.16
6.2
6.1
12.01
11.54
mg/l
0.37
63
509
0
34
0.00
1.16
0.0
1.2
—
21.50
—
0
24
347
3136
1.11
1.15
1.3
1.4
—
—
—
0
0
106
877
1.21
1.15
1.5
1.6
—
—
—
0
0
57
441
1.30
1.10
1.4
1.5
1633.25
2213.51
e6/l
0.64
44
327
7
31
2.26
1.10
1.3
1.0
—
—
—
0
0
35
251
1.40
1.10
1.1
1.3
133.97
134.95
nmol/l
0.04
35
251
184
1604
1.15
1.09
1.1
1.1
—
—
—
0
0
91
747
1.22
1.08
1.2
1.1
—
—
—
0
0
20
128
1.56
1.08
1.6
1.4
15.90
17.01
umol/l
0.68
20
119
56
434
1.29
1.08
1.6
1.5
33.49
32.46
%
0.07
37
263
12
67
1.79
1.04
1.1
1.3
1.60
1.79
mmol/l
—
6
42
19
289
0.66
1.04
1.0
1.0
575.00
742.73
ng/l
1.19
13
203
55
428
1.29
1.03
1.1
1.0
—
—
—
0
0
61
482
1.27
1.02
2.0
1.6
—
—
—
0
0
90
748
1.21
0.97
1.2
1.2
—
—
—
0
0
41
310
1.32
0.96
1.7
2.3
591.42
639.51
ml
0.47
33
220
60
479
1.25
0.94
1.3
1.5
30.46
32.70
g/l
0.65
54
437
18
117
1.54
0.93
1.1
1.2
—
—
—
0
0
30
217
1.38
0.93
1.1
1.2
—
—
—
0
0
29
209
1.39
0.92
1.6
1.6
—
—
—
0
0
29
209
1.39
0.92
1.6
1.6
—
—
—
0
0
6
28
2.14
0.91
1.0
1.4
—
—
—
0
0
20
291
0.69
0.91
1.0
1.0
38.57
45.20
ng/l
0.29
14
205
103
874
1.18
0.90
1.9
2.1
0.78
0.80
nmol/l
0.15
80
755
33
244
1.35
0.90
2.0
1.5
1.31
1.39
nmol/l
0.15
27
189
118
1013
1.17
0.90
1.8
1.7
—
—
—
0
0
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
42
323
1.30
0.89
1.2
1.0
1.17
1.07
u/l
0.46
20
144
180
1595
1.13
0.89
1.7
1.8
—
—
—
0
0
45
350
1.29
0.88
1.9
1.9
—
—
—
0
0
242
2185
1.11
0.87
1.4
1.5
—
—
—
0
0
30
220
1.37
0.87
1.3
1.6
—
—
—
0
0
12
72
1.67
0.85
1.2
1.1
—
—
—
0
0
206
2293
0.90
0.84
1.4
1.3
212.85
232.77
miu/ml
0.37
110
1123
101
863
1.17
0.83
1.4
1.4
6.71
6.96
mmol/l
0.47
90
770
290
2651
1.10
0.83
9.7
8.7
93.94
94.23
%
0.32
290
2641
20
285
0.70
0.83
1.0
1.0
282.14
337.96
ng/l
0.45
14
204
197
1771
1.12
0.79
5.0
4.9
1.83
1.67
%
1.01
183
1646
16
106
1.51
0.78
1.1
1.0
87.31
74.05
ug/l
0.43
11
91
106
917
1.16
0.77
1.2
1.2
2.19
3.73
u/ml
1.48
47
293
26
191
1.36
0.76
1.1
1.1
—
—
—
0
0
29
217
1.34
0.76
1.3
1.6
—
—
—
0
0
6
34
1.77
0.76
1.3
1.1
8.73
7.95
mmol/l
—
6
34
10
59
1.70
0.75
1.0
1.0
—
—
—
0
0
15
99
1.52
0.75
1.1
1.1
—
—
—
0
0
15
99
1.52
0.75
1.1
1.3
—
—
—
0
0
125
1097
1.14
0.75
4.2
3.3
22.59
26.00
mg/l
0.56
69
686
62
513
1.21
0.75
1.3
1.5
—
—
—
0
0
57
468
1.22
0.74
1.3
1.1
43.16
39.51
mg/l
0.21
41
392
9
55
1.64
0.73
1.3
1.4
—
—
—
0
0
171
1536
1.12
0.72
3.2
2.5
3.48
3.64
g/l
0.82
165
1448
193
1749
1.11
0.70
2.7
3.4
163.11
1277.44
u/ml
1.16
159
1480
223
2036
1.10
0.69
1.3
1.4
—
—
—
0
0
1358
13143
1.04
0.69
1.5
1.5
—
—
—
0
0
198
1799
1.10
0.68
1.5
1.5
—
—
—
0
0
25
187
1.34
0.68
1.0
1.0
—
—
—
0
0
36
285
1.26
0.66
1.1
1.0
90.25
92.96
%
0.27
24
225
287
2658
1.08
0.66
5.9
6.8
24.71
24.63
mmol/l
0.14
268
2510
14
95
1.47
0.64
2.6
1.6
1.17
1.19
mmol/l
0.57
14
90
222
2038
1.09
0.63
1.4
1.4
—
—
—
0
0
23
172
1.34
0.63
1.0
1.1
—
—
—
0
0
221
2029
1.09
0.63
1.3
1.4
—
—
—
0
0
153
1379
1.11
0.63
2.6
2.8
—
—
—
0
0
222
2040
1.09
0.62
1.4
1.4
—
—
—
0
0
8
49
1.63
0.62
1.5
1.2
—
—
—
0
0
47
388
1.21
0.61
1.4
1.5
13253.89
54359.06
e6/l
1.77
35
233
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
63
536
1.18
0.60
1.1
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
184
1681
1.10
0.59
2.6
2.1
94.33
94.44
%
0.02
174
1610
54
455
1.19
0.58
1.1
1.1
257.20
236.04
mg/l
0.32
41
400
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
25
193
1.30
0.57
1.4
1.3
115.60
189.50
nmol/24h
0.38
25
193
8
54
1.48
0.57
1.1
1.1
—
—
—
0
0
192
1764
1.09
0.56
5.1
4.9
0.89
0.90
%
0.20
179
1641
10
65
1.54
0.55
1.1
1.2
—
—
—
0
0
20
151
1.33
0.53
4.0
2.9
69.33
123.21
ng/l
—
9
61
11
74
1.49
0.53
1.2
1.3
—
—
—
0
0
6
99
0.61
0.51
3.8
1.9
13.98
16.68
umol/l
—
6
99
113
1017
1.11
0.51
1.0
1.1
1.70
1.46
u/ml
0.13
57
475
9
64
1.41
0.51
1.1
1.2
—
—
—
0
0
51
597
0.85
0.51
5.7
4.8
390.03
363.37
umol/l
0.76
42
515
22
170
1.30
0.51
1.8
2.0
—
—
—
0
0
15
109
1.38
0.50
1.1
1.1
0.44
0.69
umol/24h
—
6
49
545
5213
1.05
0.50
3.3
3.9
14.09
26.64
ug/l
0.81
419
4085
96
857
1.12
0.50
1.1
1.1
116.09
119.12
%
0.39
81
776
47
398
1.18
0.50
1.9
2.1
—
—
—
0
0
42
352
1.19
0.50
2.5
2.7
—
—
—
0
0
120
1087
1.11
0.49
1.6
1.5
—
—
—
0
0
111
1002
1.11
0.48
5.9
6.6
104.78
105.24
mmol/l
0.45
100
887
96
860
1.12
0.48
1.3
1.3
—
—
—
0
0
43
364
1.18
0.47
1.2
1.5
1.23
1.18
promille
0.07
35
274
146
1340
1.09
0.47
1.4
1.5
—
—
—
0
0
28
227
1.23
0.46
1.0
1.1
—
—
—
0
0
121
1102
1.10
0.46
1.0
1.1
3.15
5.35
u/ml
1.65
64
553
7
49
1.43
0.46
1.1
1.1
—
—
—
0
0
107
969
1.11
0.45
1.2
1.3
—
—
—
0
0
107
969
1.11
0.45
1.2
1.3
—
—
—
0
0
8
120
0.67
0.45
1.7
1.1
—
—
—
0
0
11
153
0.72
0.45
1.6
1.2
112.82
108.37
%
0.14
11
143
30
246
1.22
0.45
1.3
1.6
—
—
—
0
0
7
50
1.40
0.45
1.1
1.1
1.34
1.69
umol/24h
—
7
50
43
366
1.18
0.44
1.2
1.4
1.33
1.48
nmol/l
0.29
34
331
30
362
0.83
0.44
1.1
1.4
—
—
—
0
0
38
321
1.18
0.43
1.3
1.6
—
—
—
0
0
1169
11398
1.03
0.43
4.0
3.9
1.02
1.02
kg/l
0.14
200
1749
8
57
1.40
0.42
3.0
2.6
0.88
0.79
u/field
—
8
57
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
116
1264
0.92
0.40
3.3
4.1
3.86
3.82
mmol/l
0.47
116
1253
115
1054
1.09
0.40
1.0
1.1
0.48
1.16
u/ml
1.96
45
414
43
371
1.16
0.39
1.4
1.3
—
—
—
0
0
33
388
0.85
0.38
1.1
1.2
—
—
—
0
0
132
1223
1.08
0.37
1.1
1.1
2.41
2.08
u/ml
0.12
64
584
5
37
1.35
0.37
1.6
1.2
—
—
—
0
0
21
170
1.24
0.37
2.0
2.7
32.00
28.23
umol/l
0.64
14
129
9
70
1.29
0.36
1.6
1.6
—
—
—
0
0
9
71
1.27
0.36
3.1
2.0
—
—
—
0
0
6
43
1.40
0.35
5.5
2.6
—
—
—
0
0
261
2742
0.95
0.34
1.4
1.5
—
—
—
0
0
129
1200
1.08
0.34
2.6
3.2
1.56
1.44
mg/l
0.90
122
1118
29
246
1.18
0.34
2.8
2.4
16.65
237.71
ug/l
0.98
29
231
16
127
1.26
0.33
2.1
3.6
—
—
—
0
0
16
127
1.26
0.33
2.1
3.7
—
—
—
0
0
187
1765
1.06
0.33
1.6
1.6
0.36
0.66
iu/ml
0.25
33
361
82
893
0.92
0.31
1.2
1.2
—
—
—
0
0
38
334
1.14
0.30
2.0
1.6
—
—
—
0
0
14
111
1.26
0.30
1.1
1.2
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
13
163
0.80
0.29
1.6
2.3
656.75
853.06
e6/l
—
8
114
34
388
0.88
0.29
2.8
1.9
2.20
2.16
u/field
0.02
15
167
69
632
1.09
0.28
1.2
1.2
18.29
33.42
u/l
1.50
61
539
8
62
1.29
0.28
4.6
5.2
—
—
—
0
0
422
4086
1.04
0.27
3.1
3.4
49.12
50.28
u/ml
0.04
405
3955
32
280
1.14
0.27
2.0
2.7
41.74
44.04
%
0.34
16
166
13
160
0.81
0.26
1.0
1.1
—
—
—
0
0
660
6446
1.03
0.25
1.5
1.7
1.34
1.38
%
1.08
581
5742
9
73
1.23
0.25
1.0
1.0
—
—
—
0
0
608
5936
1.03
0.24
6.2
5.9
—
—
—
0
0
10
78
1.28
0.24
1.2
1.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
25
284
0.88
0.22
1.6
2.8
—
—
—
0
0
14
116
1.21
0.22
1.1
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
102
0.78
0.21
1.0
1.1
—
—
—
0
0
5
43
1.16
0.21
1.4
1.4
58.80
42.79
umol/l
—
5
43
0
13
0.00
0.21
0.0
1.2
—
7.15
—
0
13
64
595
1.08
0.20
1.1
1.2
—
—
—
0
0
79
842
0.94
0.20
1.1
1.1
1.32
3.95
u/ml
2.74
30
336
11
134
0.82
0.20
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
6
49
1.22
0.20
1.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
38
346
1.10
0.19
1.8
1.4
73.18
72.95
umol/l
0.02
38
346
23
204
1.13
0.18
1.9
2.1
192.20
124.38
ug/min
—
5
37
7
61
1.15
0.17
1.7
2.4
15.87
14.95
ml/dl
—
7
55
36
330
1.09
0.16
1.1
1.2
—
—
—
0
0
93
885
1.05
0.16
1.3
1.2
2.96
4.10
u/ml
0.88
47
357
8
69
1.16
0.16
1.3
1.3
—
—
—
0
0
6
80
0.75
0.15
1.0
1.0
—
—
—
0
0
38
351
1.08
0.15
1.6
1.5
—
—
—
0
0
70
739
0.95
0.15
1.0
1.0
0.11
0.27
u/ml
1.12
20
192
236
2296
1.03
0.15
1.9
1.6
3.43
4.17
mg/l
0.91
190
1657
42
390
1.08
0.15
2.6
2.7
464.65
540.92
e6/l
0.64
37
328
417
4088
1.02
0.15
2.8
2.4
67.78
70.46
ml/min/173m2
0.65
183
1550
90
859
1.05
0.15
1.2
1.1
—
—
—
0
0
162
1568
1.03
0.14
3.6
2.3
170.74
182.13
%
1.16
155
1488
19
212
0.90
0.14
1.2
1.1
86.25
94.37
%
—
8
78
25
228
1.10
0.13
1.4
1.5
4.63
4.00
%
—
8
43
43
403
1.07
0.13
1.3
1.4
22.33
32.64
nmol/l
2.19
37
369
373
3793
0.98
0.11
1.7
1.7
—
—
—
0
0
706
6980
1.01
0.11
1.9
1.9
—
—
—
0
0
47
446
1.05
0.10
1.4
1.4
23518.63
60087.35
e6/l
0.78
30
312
19
207
0.92
0.09
1.2
1.2
86.22
95.34
%
—
9
80
14
126
1.11
0.09
1.1
1.0
—
—
—
0
0
21
194
1.08
0.09
3.1
3.5
—
—
—
0
0
15
165
0.91
0.08
1.7
1.6
9.02
8.50
ug/l
0.13
15
165
42
441
0.95
0.08
2.9
2.7
—
—
—
0
0
19
175
1.09
0.08
2.9
4.2
—
—
—
0
0
10
113
0.88
0.08
1.1
1.1
—
—
—
0
0
26
277
0.94
0.08
3.2
1.7
0.95
2.65
u/field
2.52
19
194
14
127
1.10
0.07
1.1
1.1
—
—
—
0
0
14
127
1.10
0.07
1.1
1.1
—
—
—
0
0
18
166
1.08
0.07
3.6
3.5
—
—
—
0
0
203
2064
0.98
0.07
1.7
1.8
—
—
—
0
0
25
235
1.06
0.07
1.3
1.6
—
1810015.33
—
0
15
562
5669
0.99
0.07
1.6
1.6
—
—
—
0
0
16
173
0.92
0.06
1.1
1.1
5.01
11.38
u/ml
1.26
11
112
87
892
0.98
0.06
1.1
1.1
3.20
3.40
u/ml
0.05
34
396
55
532
1.03
0.06
1.1
1.0
—
—
—
0
0
98
958
1.02
0.06
3.1
3.3
43.31
586.76
u/ml
1.30
90
873
12
131
0.92
0.05
1.1
1.2
—
—
—
0
0
43
415
1.04
0.05
3.5
4.2
—
—
—
0
0
486
4893
0.99
0.04
1.7
1.8
—
—
—
0
0
27
282
0.96
0.04
1.2
1.1
—
—
—
0
0
37
383
0.97
0.04
1.2
1.1
—
—
—
0
0
16
150
1.07
0.04
1.2
1.1
—
—
—
0
0
37
358
1.03
0.04
1.7
1.9
3.41
3.43
mg/l
0.02
37
341
27
281
0.96
0.04
1.1
1.1
1517.85
1523.62
miu/ml
0.01
27
281
42
408
1.03
0.04
1.1
1.1
—
—
—
0
0
13
139
0.94
0.03
1.4
2.0
2822.00
21979.14
e6/l
—
5
76
91
896
1.02
0.03
1.1
1.1
—
—
—
0
0
17
179
0.95
0.03
1.3
1.4
210.35
202.99
pmol/l
0.04
17
179
11
102
1.08
0.03
1.8
2.4
—
—
—
0
0
12
128
0.94
0.02
1.2
1.3
100.53
106.78
nmol/l
0.09
12
88
47
461
1.02
0.02
1.1
1.1
—
—
—
0
0
10
106
0.94
0.01
1.0
1.1
—
—
—
0
0
13
124
1.05
0.00
1.1
1.1
—
—
—
0
0
19
184
1.03
0.00
2.2
2.4
—
—
—
0
0
784
7848
1.00
0.00
2.0
2.0
—
—
—
0
0
39
384
1.02
0.00
1.3
1.3
1.60
1.60
g/l
0.02
39
384
39
396
0.98
0.00
1.0
1.1
4.73
9.15
iu/ml
—
7
98
60
606
0.99
0.00
2.2
2.3
—
—
—
0
0
21
212
0.99
0.00
1.0
1.1
—
—
—
0
0
20
195
1.03
0.00
1.1
1.2
—
—
—
0
0
45
448
1.00
0.00
1.4
1.4
0.95
0.93
g/l
0.17
45
448
32
315
1.02
0.00
1.0
1.6
13.90
8.65
ug/l
0.27
25
278
15
154
0.97
0.00
1.3
1.1
53.64
52.71
u/ml
0.02
15
147
16
163
0.98
0.00
3.4
2.2
156.13
151.18
nmol/l
0.06
16
136
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
2.0
2.2
45.44
58.78
pmol/l
—
5
47
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
2.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_THYTOXGOITDIF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYTOXGOITDIF | 1.072 [0.97, 1.19] | 0.195 |
| Birth year | 0.998 [0.99, 1.01] | 0.668 |
During the follow-up period (1.1.1998 — 31.12.2019), 2220 out of 23978 females with E4_THYTOXGOITDIF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYTOXGOITDIF | 1.256 [1.11, 1.42] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 772 out of 5286 males with E4_THYTOXGOITDIF died.
Mortality risk
Mortality risk for people of age
years, who have E4_THYTOXGOITDIF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.133% | 0.248% |
| 5 | 0.717% | 1.366% |
| 10 | 1.728% | 3.515% |
| 15 | 3.315% | 6.757% |
| 20 | 5.89% | 11.323% |
Relationships between endpoints
↥Index endpoint: E4_THYTOXGOITDIF – Thyrotoxicosis with diffuse goitre
GWS hits: 30
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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