Autoimmune hyperthyroidism

AUTOIMMUNE_HYPERTHYROIDISM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • E4_THYTOXGOITDIF
6542

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E05.9
  • Cause of death: ICD-10 E05.9

2 out of 7 registries used, show all original rules.

2712

4. Check minimum number of events

None

2712

5. Include endpoints

None

2712

6. Filter based on genotype QC (FinnGen only)

2609

Control definitions (FinnGen only)

Control exclude
AUTOIMMUNE
Control conditions
not E4_THYTOXGOITDIF

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14824 11965 2766
Only index persons 14358 11690 2668
Unadjusted period prevalence (%)
Whole population 0.29 0.34 0.08
Only index persons 0.37 0.43 0.10
Median age at first event (years)
Whole population 50.67 50.39 52.43
Only index persons 50.46 50.13 51.92

-FinnGen-

Key figures

All Female Male
Number of individuals 2609 2171 438
Unadjusted period prevalence (%) 0.67 0.77 0.20
Median age at first event (years) 50.99 49.87 56.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2712
Matched controls
27120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
28.1
311.8
213
82
T86
ICPC
Hypothyroidism/myxoedema
30.4
307.7
269
98
C07AA05
ATC
propranolol; systemic
5.4
307.7
1252
3723
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
349304.0
307.7
2693
11
BAA60
NOMESCO Finland
Total thyroidectomy
35.0
307.7
746
291
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
31.0
307.7
274
98
H03BB01
ATC
carbimazole; oral
1074.7
307.7
2448
232
104
Kela drug reimbursment
Thyroid insufficiency
39.9
307.7
809
286
E03.89
ICD-10 Finland
Other specified hypothyroidism
29.0
307.7
251
95
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
728
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
40.7
307.7
541
165
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
1015.8
307.7
2386
194
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
35.1
307.7
673
253
E03
ICD-10 Finland
Other hypothyroidism
30.4
307.7
316
117
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
82.9
307.7
421
60
H03AA01
ATC
levothyroxine sodium; systemic
94.7
307.7
2077
905
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
128.3
307.7
423
39
T85
ICPC
Hyperthyroidism/thyrotoxicosis
67.5
301.4
165
26
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
31.8
297.8
195
66
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
17.9
289.8
240
146
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
78.2
263.6
141
19
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
82.2
222.1
118
15
H062, E050,
ICD-10 Finland
+∞
208.0
197
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
207.5
1226
5301
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
184.5
175
*
E05.89
ICD-10 Finland
Other thyrotoxicosis
83.8
183.0
97
12
C07AB07
ATC
bisoprolol; oral
3.0
170.6
1490
7831
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.7
170.0
346
681
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
42.3
163.0
98
24
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
74.0
159.3
86
12
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
25.8
156.0
109
44
L04AX03
ATC
methotrexate; systemic
7.1
154.3
245
376
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
150.3
1477
8091
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
57.3
138.4
78
14
K90.0
ICD-10 Finland
Coeliac disease
18.8
125.8
100
55
H04AA01
ATC
glucagon; nasal, parenteral
66.6
118.3
65
10
H50.2
ICD-10 Finland
Vertical strabismus
17.2
114.6
95
57
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
14.0
106.9
99
73
H53.2
ICD-10 Finland
Diplopia
6.5
106.1
179
291
A10AA01, ,
ATC
55.8
105.8
60
11
T89
ICPC
Diabetes insulin dependent
12.8
103.0
101
82
E06.3
ICD-10 Finland
Autoimmune thyroiditis
52.9
99.5
57
11
H02AB06
ATC
prednisolone; systemic
2.3
99.2
1365
8231
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
121.3
97.7
105
9
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
31.7
95.3
62
20
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.4
87.7
354
1151
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
29.6
87.2
58
20
A10AB01
ATC
insulin (human); parenteral
16.6
86.7
73
45
H05.2
ICD-10 Finland
Exophthalmic conditions
156.9
86.6
91
6
E10
ICD-10 Finland
Type 1 diabetes mellitus
41.6
81.0
49
12
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
790.8
78.8
77
*
XCK00
NOMESCO Finland
Perimetry
4.0
78.6
238
637
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
7.6
77.8
112
153
H03BA02
ATC
propylthiouracil; oral
253.5
72.7
74
*
A10AB04
ATC
insulin lispro; parenteral
11.1
72.3
77
71
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.5
72.1
183
428
H02AB07
ATC
prednisone; oral
2.8
70.7
414
1655
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
14.8
68.3
61
42
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
67.0
511
2320
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
28.6
66.8
45
16
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
65.9
63
*
ZX120
NOMESCO Finland
Intravenous
3.1
65.5
292
1002
A10AA02, ,
ATC
12.9
64.1
62
49
A11CC03
ATC
alfacalcidol; systemic
6.8
63.5
101
154
L01BA01
ATC
methotrexate; systemic
14.5
63.1
57
40
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
60.2
401
1702
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.3
59.3
157
379
CEC00
NOMESCO Finland
Recession of extraocular muscle
18.7
57.9
46
25
A10AB05
ATC
insulin aspart; parenteral
4.1
55.8
160
410
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
21.9
55.2
41
19
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
54.2
1105
7220
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
190.5
54.2
56
*
A07EC02
ATC
mesalazine; oral, rectal
6.7
52.4
84
129
P01BA02
ATC
hydroxychloroquine; oral
4.2
51.7
144
361
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
50.2
48
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.5
48.0
94
176
E05.5
ICD-10 Finland
Thyroid crisis or storm
476.0
47.5
47
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.7
46.2
87
157
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
44.4
576
3195
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
+∞
43.9
42
*
A10AE05
ATC
insulin detemir; parenteral
4.5
43.7
110
255
CA1AD
NOMESCO Finland
Orbita CT
57.7
43.5
51
9
106
Kela drug reimbursment
Hypoparathyroidism
13.5
42.6
40
30
XCK10
NOMESCO Finland
Photography of fundus of eye
2.8
42.5
224
839
ZXA10
NOMESCO Finland
Bilateral
2.0
42.1
511
2762
L04AA13
ATC
[U] leflunomide
11.5
41.4
43
38
C07AB02
ATC
metoprolol; systemic
2.1
40.5
481
2577
A07EC01
ATC
sulfasalazine; oral, rectal
3.8
40.1
127
349
K51.5
ICD-10 Finland
Left sided colitis
89.5
39.9
44
5
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
39.6
954
6404
WF099
NOMESCO Finland
Other radiotherapy
10.4
39.6
44
43
L04AX01
ATC
azathioprine; systemic
7.4
39.5
57
78
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
106.6
38.8
42
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
38.5
417
2156
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.2
37.8
156
508
A10AE06
ATC
insulin degludec; parenteral
5.7
37.3
70
126
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.5
36.8
131
389
H50.6
ICD-10 Finland
Mechanical strabismus
98.9
35.8
39
*
A02BC02
ATC
pantoprazole; systemic
1.7
35.4
1780
14380
L40.0
ICD-10 Finland
Psoriasis vulgaris
7.1
35.2
53
76
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
47.3
34.7
42
9
107
Kela drug reimbursment
Pernicious anaemia
+∞
34.4
33
*
CAC44
NOMESCO Finland
Combined decompression of orbit
341.4
34.0
34
*
A10AC01
ATC
insulin (human); parenteral
3.2
33.8
140
457
H50.8
ICD-10 Finland
Other specified strabismus
50.7
33.5
40
8
H02AB09
ATC
hydrocortisone; systemic
5.0
32.9
71
145
H50.0
ICD-10 Finland
Convergent concomitant strabismus
8.1
32.9
44
55
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
32.8
674
4283
C01BD01
ATC
amiodarone; systemic
4.5
32.5
79
178
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
10.1
31.8
36
36
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
31.1
596
3703
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
31.1
679
4380
TFP20
NOMESCO Finland
Cardiodefibrillation
2.8
30.9
163
609
A10AE04
ATC
insulin glargine; parenteral
2.7
30.6
174
676
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
7.5
30.1
43
58
G35
ICD-10 Finland
Multiple sclerosis
156.7
29.7
31
*
E83.51
ICD-10 Finland
Hypocalcemia
8.2
29.5
39
48
L88
ICPC
Rheumatoid/seropositive arthritis
5.4
29.5
58
109
Z3231
NOMESCO Finland
Registered nurse
1.7
29.4
669
4353
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
29.2
28
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
7.0
28.4
43
62
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
28.2
27
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.0
27.3
121
411
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
+∞
27.1
26
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
27.0
159
629
2AB04, ,
NOMESCO Finland
75.9
26.8
30
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
141.4
26.7
28
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
26.6
982
7178
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
52.2
26.2
31
6
H3600, E103,
ICD-10 Finland
+∞
26.1
25
*
C03CA01
ATC
furosemide; systemic
1.7
26.0
548
3478
B03BA03
ATC
hydroxocobalamin; parenteral
3.3
25.9
101
318
L04AA06
ATC
mycophenolic acid; systemic
5.9
25.7
46
79
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
25.3
25.3
35
14
WX402
NOMESCO Finland
General anaesthesia
1.7
25.2
573
3708
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
+∞
25.0
24
*
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
+∞
25.0
24
*
K51.8
ICD-10 Finland
Other ulcerative colitis
+∞
25.0
24
*
109
Kela drug reimbursment
Multiple sclerosis
+∞
25.0
24
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
+∞
25.0
24
*
R00.2
ICD-10 Finland
Palpitations
2.1
25.0
252
1259
N05CF01
ATC
zopiclone; oral
1.6
24.8
779
5464
R53
ICD-10 Finland
Malaise and fatigue
1.7
24.4
620
4125
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
6.3
24.0
40
64
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
+∞
24.0
23
*
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
+∞
24.0
23
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
23.9
154
636
R06.0
ICD-10 Finland
Dyspnoea
1.6
23.7
626
4201
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
23.5
552
3597
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.0
23.4
41
69
A07EA06
ATC
budesonide; oral, local oral
4.6
23.1
54
118
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
36.6
23.0
29
8
207
Kela drug reimbursment
Chronic arrhythmias
1.9
22.5
292
1594
H3603, E103,
ICD-10 Finland
+∞
21.9
21
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.1
21.9
215
1063
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.4
21.7
161
709
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
20.9
20
*
H3601, E103,
ICD-10 Finland
+∞
20.9
20
*
A04
ICPC
Weakness/tiredness general
1.8
20.5
362
2174
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.6
20.4
119
469
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
48.4
20.2
24
5
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
58.0
19.9
23
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
58.0
19.9
23
*
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
19.7
225
1175
A07EA02
ATC
hydrocortisone; rectal
6.9
19.5
30
44
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
55.4
18.9
22
*
A02BC05
ATC
esomeprazole; systemic
1.5
18.9
1004
7777
B01AA03
ATC
warfarin; systemic
1.8
18.8
327
1953
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
18.8
18
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
38.7
18.5
23
6
K04
ICPC
Palpitations/awareness of heart
2.2
18.4
150
688
1XC02, ,
NOMESCO Finland
7.9
18.3
25
32
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
17.9
706
5146
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
18.2
17.8
27
15
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
17.7
363
2267
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
+∞
17.7
17
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
+∞
17.7
17
*
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
17.7
17
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
181.1
17.5
18
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
17.5
284
1662
N02BE01
ATC
paracetamol; systemic, rectal
1.6
17.5
2331
21388
CS494
NOMESCO Finland
Other visual field testing
3.2
17.4
68
215
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
17.3
311
1873
ZXE00
NOMESCO Finland
One hour or less
1.4
17.3
967
7534
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
17.2
346
2151
C07AA07
ATC
sotalol; systemic
2.9
17.1
78
270
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
17.0
936
7263
J01DB01
ATC
cefalexin; oral
1.5
16.8
2139
19290
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
16.7
431
2852
A12AA04
ATC
calcium carbonate; oral
5.1
16.7
35
70
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
16.7
427
2821
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
16.5
1854
16286
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
5.0
16.4
35
71
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
40.3
16.3
20
5
N02AX02
ATC
tramadol; systemic, rectal
1.4
16.3
958
7508
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
16.2
946
7406
H02AB04
ATC
methylprednisolone; systemic
1.7
15.8
331
2077
K50.9
ICD-10 Finland
Crohn disease, unspecified
60.4
15.8
18
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
15.6
15
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
15.6
15
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.6
15.6
50
139
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
19.3
15.5
23
12
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
160.9
15.5
16
*
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.8
15.4
34
71
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
15.4
251
1468
XF404
NOMESCO Finland
Ambulatory ECG
1.9
15.4
186
990
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
15.2
323
2034
CKC12
NOMESCO Finland
Photocoagulation of retina
2.6
15.1
85
329
XCH00
NOMESCO Finland
Eye pressure measurement
2.4
15.0
106
457
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.6
14.9
35
77
L04AB04
ATC
adalimumab; parenteral
6.5
14.9
24
37
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
14.8
280
1709
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
3.8
14.8
45
121
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
14.7
163
841
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
14.7
1015
8141
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
14.7
441
3015
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.0
14.7
159
814
H57.1
ICD-10 Finland
Ocular pain
2.4
14.7
102
437
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
14.5
203
1134
E05.3
ICD-10 Finland
Thyrotoxicosis from ectopic thyroid tissue
150.8
14.5
15
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
150.8
14.5
15
*
UJF32
NOMESCO Finland
Coloscopy
1.5
14.4
511
3623
M01CB01
ATC
sodium aurothiomalate; parenteral
27.3
14.3
19
7
E06.1
ICD-10 Finland
Subacute thyroiditis
4.9
14.3
31
64
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
14.2
678
5090
B81
ICPC
Anaemia vit B12/folate deficiency
3.1
14.2
58
189
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
14.0
439
3030
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
30.2
13.9
18
6
H01.0
ICD-10 Finland
Blepharitis
1.9
13.8
174
939
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
23.9
13.8
19
8
N06AX21
ATC
duloxetine; oral
1.7
13.7
288
1807
Z2221
NOMESCO Finland
Medical doctor
1.4
13.6
679
5134
F29
ICPC
Eye symptom/complaint other
1.7
13.6
235
1398
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
13.5
13
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
13.5
85
348
CA1BD
NOMESCO Finland
Extensive orbita CT
34.2
13.5
17
5
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
140.7
13.5
14
*
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
140.7
13.5
14
*
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
13.4
506
3628
K80
ICPC
Cardiac arrhythmia NOS
1.8
13.3
190
1068
A11CC02
ATC
dihydrotachysterol; oral
15.1
13.1
21
14
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
22.6
12.9
18
8
SPAT1262
SPAT
Handing over of treatment supplies
1.6
12.5
311
2032
353
Kela drug reimbursment
Cladribine and fingolimod
+∞
12.5
12
*
164
Kela drug reimbursment
Fingolimod
+∞
12.5
12
*
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
+∞
12.5
12
*
L28
ICPC
Limited function/disability (L)
1.6
12.5
343
2295
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
12.5
338
2254
L01BB02
ATC
mercaptopurine; oral
24.4
12.5
17
7
M14.5*E05.9
ICD-10 Finland
Arthropathy in thyrotoxicosis [hyperthyroidism]
130.6
12.4
13
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
12.4
244
1505
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
12.4
651
4959
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
3.9
12.4
36
94
R02
ICPC
Shortness of breath/dyspnoea
1.6
12.3
276
1759
M54.5
ICD-10 Finland
Low back pain
1.4
12.3
893
7175
E06.9
ICD-10 Finland
Thyroiditis, unspecified
9.7
12.2
24
25
L13.0
ICD-10 Finland
Dermatitis herpetiformis
37.7
12.2
15
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
12.2
595
4471
R50.9
ICD-10 Finland
Fever, unspecified
1.6
12.1
304
1993
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
3.7
12.0
38
105
L40.5
ICD-10 Finland
Arthropathic psoriasis
26.8
12.0
16
6
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
12.0
92
412
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.0
11.9
33
83
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
11.7
175
998
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
30.2
11.6
15
5
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
65.2
11.6
13
*
E06.4
ICD-10 Finland
Drug-induced thyroiditis
65.2
11.6
13
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
65.2
11.6
13
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
11.6
162
905
TFP34
NOMESCO Finland
Electrophysiological investigation
2.4
11.5
78
331
J01FF01
ATC
clindamycin; systemic
1.4
11.5
591
4475
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
11.5
1049
8699
TNG10
NOMESCO Finland
Puncture of knee
5.7
11.5
21
37
L04AA27
ATC
[U] fingolimod
+∞
11.5
11
*
L03AX13
ATC
glatiramer acetate; parenteral
+∞
11.5
11
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
11.4
722
5658
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
120.5
11.4
12
*
C01BC04
ATC
flecainide; systemic
2.4
11.4
78
333
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
11.4
160
895
W84
ICPC
Pregnancy high risk
2.2
11.3
91
416
N05BA04
ATC
oxazepam; oral
1.4
11.3
615
4699
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
11.3
1388
11999
SPAT1263
SPAT
Sampling
1.3
11.3
964
7911
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
2.6
11.3
65
256
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
35.2
11.3
14
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
4.5
11.2
27
61
A02BC01
ATC
omeprazole; systemic
1.4
11.1
599
4568
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
12.7
11.1
19
15
R63.4
ICD-10 Finland
Abnormal weight loss
2.3
11.1
81
356
XF402
NOMESCO Finland
ECG with work load test
1.7
11.1
197
1181
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
11.1
677
5275
WZC30
NOMESCO Finland
Teaching
1.5
11.0
319
2157
AA1AD
NOMESCO Finland
CT of head and brain
1.4
11.0
529
3954
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
11.0
276
1806
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
11.0
346
2383
N03AX16
ATC
[U] pregabalin
1.4
11.0
501
3711
M05BA04
ATC
alendronic acid; oral
1.8
10.9
164
936
K29.4
ICD-10 Finland
Chronic atrophic gastritis
3.6
10.9
35
98
E0000UV, ,
ATC
1.3
10.9
958
7888
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
10.8
301
2017
WX892
NOMESCO Finland
Monitored bed care
1.9
10.8
140
763
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.1
10.8
101
491
L17
ICPC
Foot/toe symptom/complaint
1.4
10.8
640
4958
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.5
10.8
67
274
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.3
10.7
77
336
H05.0
ICD-10 Finland
Acute inflammation of orbit
28.1
10.7
14
5
I47.2
ICD-10 Finland
Ventricular tachycardia
3.3
10.7
40
124
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
10.7
839
6789
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
10.6
162
929
C03DA01
ATC
spironolactone; oral
1.7
10.6
211
1304
Z71.8
ICD-10 Finland
Other specified counselling
1.4
10.4
747
5956
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
+∞
10.4
10
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
10.4
10
*
K51
ICD-10 Finland
Ulcerative colitis
32.6
10.3
13
*
M25.5
ICD-10 Finland
Pain in joint
1.3
10.3
774
6214
B01AF02
ATC
apixaban; oral
1.6
10.3
216
1354
C01AA05
ATC
digoxin; systemic
2.0
10.2
116
605
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
4.6
10.2
24
53
N86
ICPC
Multiple sclerosis
23.4
10.2
14
6
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
10.2
188
1138
R51.80
ICD-10 Finland
Headache
1.5
10.2
384
2741
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
10.2
260
1709
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
10.1
237
1526
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
4.2
10.1
26
62
SPAT1097
SPAT
Recording of ECG
1.5
10.1
281
1885
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
10.0
245
1596
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
9.9
418
3047
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
16.8
9.9
15
9
R03AC02
ATC
salbutamol; inhalant
1.3
9.8
1362
11875
R42
ICD-10 Finland
Dizziness and giddiness
1.4
9.8
487
3659
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
9.7
149
856
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
9.6
410
2995
A99
ICPC
Disease/condition unspecnature/site
1.7
9.6
195
1212
RD210, ,
NOMESCO Finland
3.2
9.6
36
112
R07.0
ICD-10 Finland
Pain in throat
1.7
9.5
174
1051
B01AB05
ATC
enoxaparin; parenteral
1.3
9.5
684
5445
H36.00
ICD-10 Finland
Diabetic background retinopathy
7.1
9.5
22
31
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.7
9.5
49
183
N07BA03
ATC
varenicline; oral
1.9
9.5
110
579
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.4
943
7862
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
100.4
9.4
10
*
L04AA24
ATC
abatacept; parenteral
100.4
9.4
10
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
100.4
9.4
10
*
M03BX02
ATC
tizanidine; oral
1.3
9.4
1591
14198
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
9.4
114
609
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.6
9.4
54
213
A60
ICPC
General and Unspecified, Result test/procedure
2.0
9.4
101
518
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
9.4
9
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
9.4
9
*
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
5.2
9.4
19
37
N06AX11
ATC
mirtazapine; oral
1.3
9.3
782
6361
S01XA18
ATC
ciclosporin; ophthalmic
4.9
9.3
20
41
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.9
9.3
111
590
CE2W4
NOMESCO Finland
Eye movement mapping
10.7
9.3
17
16
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
9.3
159
945
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
9.2
208
1327
Z3226
NOMESCO Finland
Physiotherapist
1.4
9.2
384
2793
L01
ICPC
Neck symptom/complaint
1.4
9.1
380
2762
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
9.1
112
602
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.8
9.1
44
159
K78
ICPC
Atrial fibrillation/flutter
1.9
9.0
120
662
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
9.0
279
1915
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.0
1840
16783
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
8.9
417
3094
WX002
NOMESCO Finland
Sedation and analgesia
1.4
8.9
393
2886
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
24.1
8.9
12
5
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.9
1451
12852
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.9
787
6447
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
8.8
519
4000
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
8.8
159
960
D05AX52
ATC
calcipotriol, combinations; topical
2.2
8.7
69
315
E20.8
ICD-10 Finland
Other hypoparathyroidism
50.1
8.7
10
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
50.1
8.7
10
*
O90.5
ICD-10 Finland
Postpartum thyroiditis
50.1
8.7
10
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
8.7
615
4878
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
8.6
424
3172
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
4.6
8.6
20
44
R60.0
ICD-10 Finland
Localized oedema
1.5
8.6
234
1561
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.9
8.6
100
528
R01AD08
ATC
fluticasone; nasal
1.3
8.6
703
5691
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
11.6
8.6
15
13
R4110
NOMESCO Finland
Physiotherapy
1.3
8.5
595
4705
J01AA02
ATC
doxycycline; systemic
1.3
8.5
1939
17853
J01MA12
ATC
levofloxacin; systemic
1.4
8.5
337
2427
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
8.5
284
1979
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
20.1
8.5
12
6
A10AD04
ATC
insulin lispro; parenteral
20.1
8.5
12
6
D05AX02
ATC
calcipotriol; topical
2.7
8.5
45
171
R21
ICPC
Throat symptom/complaint
1.4
8.4
524
4071
G70.0
ICD-10 Finland
Myasthenia gravis
90.3
8.4
9
*
L04AA01
ATC
[U] ciclosporin
4.5
8.4
20
45
TFP35
NOMESCO Finland
Electroanatomical mapping
3.0
8.3
36
122
D01
ICPC
Abdominal pain/cramps general
1.5
8.3
275
1910
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
8.3
71
334
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
+∞
8.3
8
*
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
+∞
8.3
8
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
+∞
8.3
8
*
L04AA31
ATC
[U] teriflunomide
+∞
8.3
8
*
L03AB07
ATC
interferon beta-1a; parenteral
+∞
8.3
8
*
J01FA06
ATC
roxithromycin; oral
1.3
8.3
936
7894
R05
ICPC
Cough
1.3
8.3
550
4314
N03AX12
ATC
[U] gabapentin; oral
1.4
8.3
340
2464
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
8.3
292
2057
3AC01, ,
NOMESCO Finland
4.2
8.2
21
50
SXC03
NOMESCO Finland
Other oral or dental procedure
3.6
8.1
26
73
H46
ICD-10 Finland
Optic neuritis
4.8
8.1
18
38
CD2S4
NOMESCO Finland
Photography of eye
4.8
8.1
18
38
M07.3
ICD-10 Finland
Other psoriatic arthropathies
33.4
8.1
10
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.1
595
4740
AN1
HP
Coronary angiography
1.7
8.1
155
951
R4110, ,
SPAT
1.6
8.0
184
1179
WX140
NOMESCO Finland
Parabulbar anesthesy
2.0
8.0
79
393
D07AD01
ATC
clobetasol; topical
1.4
8.0
331
2400
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
8.9
8.0
16
18
SGA01
NOMESCO Finland
Emergency treatment
1.4
8.0
386
2879
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
8.0
533
4185
ZXD05
NOMESCO Finland
Urgent procedure
1.3
8.0
689
5610
R52.9
ICD-10 Finland
Pain, unspecified
1.6
8.0
207
1367
A02BC03
ATC
lansoprazole; oral
1.3
7.9
593
4734
A01
ICPC
Pain general/multiple sites
1.6
7.9
193
1257
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
4.0
7.9
22
56
A10AA03, ,
ATC
13.1
7.9
13
10
H50.52
ICD-10 Finland
Exophoria
3.1
7.9
32
105
J01FA10
ATC
azithromycin; systemic
1.3
7.8
1452
12967
L04AB01
ATC
etanercept; parenteral
6.1
7.8
20
33
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.8
416
3153
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.0
7.8
79
398
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.8
1250
10980
SPAT1283
SPAT
Restricted health certificate
1.4
7.7
447
3432
A08
ICPC
Swelling
1.8
7.7
103
569
E05.81
ICD-10 Finland
Overproduction of thyroid-stimulating hormone
45.1
7.7
9
*
M01AH01
ATC
celecoxib; oral
1.4
7.7
364
2706
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.6
1266
11152
C08CA01
ATC
amlodipine; oral
1.3
7.6
705
5790
M01AH05
ATC
etoricoxib; oral
1.3
7.5
1522
13700
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.5
182
1182
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
2.6
7.5
43
170
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.5
396
2996
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
7.1
7.5
17
24
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.7
7.4
124
732
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
7.4
685
5616
H25.8
ICD-10 Finland
Other senile cataract
1.6
7.4
172
1106
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
7.4
94
511
R06AE07
ATC
cetirizine; oral
1.3
7.4
1095
9507
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
7.4
114
658
M79.6
ICD-10 Finland
Pain in limb
1.3
7.4
990
8498
M01CB03
ATC
auranofin; oral
13.4
7.4
12
9
M79.7
ICD-10 Finland
Fibromyalgia
1.9
7.4
84
441
R74
ICPC
Upper respiratory infection acute
1.3
7.3
814
6830
K29
ICPC
Cardiovascular sympt/complt other
2.1
7.3
70
345
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
2.9
7.3
33
115
R03BA02
ATC
budesonide; inhalant
1.4
7.3
410
3131
108
Kela drug reimbursment
Myasthenia gravis
+∞
7.3
7
*
H3602, E103,
ICD-10 Finland
+∞
7.3
7
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
7.3
7
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
+∞
7.3
7
*
R5110, ,
SPAT
1.7
7.2
125
746
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
7.2
223
1529
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
3.7
7.2
22
60
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
1.9
7.2
83
438
ZXA00
NOMESCO Finland
Right side
1.3
7.2
523
4152
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.1
7.2
63
301
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
30.1
7.1
9
*
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
20.1
7.1
10
5
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
2.8
7.1
35
128
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.1
7.1
68
336
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
7.1
168
1087
A29
ICPC
General symptom/complaint other
1.5
7.1
243
1702
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
7.1
405
3102
J01CA04
ATC
amoxicillin; systemic
1.3
7.1
2088
19571
A10AD01
ATC
insulin (human); parenteral
5.6
7.1
19
34
E07.89
ICD-10 Finland
Other specified disorders of thyroid
10.0
7.0
13
13
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
2.5
7.0
43
176
H02.4
ICD-10 Finland
Ptosis of eyelid
2.1
7.0
60
284
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.0
787
6609
R07.3
ICD-10 Finland
Other chest pain
1.5
7.0
208
1416
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
7.0
564
4542
F01
ICPC
Eye pain
2.1
7.0
62
298
I50.0
ICD-10 Finland
Congestive heart failure
1.8
7.0
93
515
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
6.9
73
373
F13
ICPC
Eye sensation abnormal
2.1
6.9
63
305
Z01.7
ICD-10 Finland
Laboratory examination
1.4
6.9
323
2392
R13
ICD-10 Finland
Dysphagia
1.7
6.9
125
755
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
6.9
78
409
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
6.9
116
688
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.9
545
4376
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
6.9
809
6829
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.8
282
2044
M01AB55
ATC
diclofenac, combinations; oral
1.7
6.8
119
712
P06
ICPC
Sleep disturbance
1.4
6.8
252
1791
C09AA05
ATC
ramipril; oral
1.3
6.8
406
3129
NG1DA
NOMESCO Finland
X-ray of knees
2.9
6.8
31
109
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.6
6.8
37
143
Z00.8
ICD-10 Finland
Other general examinations
1.6
6.8
163
1058
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
6.8
105
608
K74.3
ICD-10 Finland
Primary biliary cirrhosis
40.2
6.8
8
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
6.7
172
1132
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
3.5
6.7
22
63
T99
ICPC
Endocr/metab/nutrit disease other
2.7
6.7
33
121
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
2.0
6.7
70
358
SPAT1281
SPAT
Other administrative function
1.6
6.7
154
991
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.0
6.6
28
94
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
3.7
6.6
20
54
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.7
6.6
114
680
L63.9
ICD-10 Finland
Alopecia areata, unspecified
6.4
6.6
16
25
A28
ICPC
Limited function/disability NOS
1.4
6.6
273
1979
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.9
6.6
17
29
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
6.6
211
1458
R11
ICD-10 Finland
Nausea and vomiting
1.5
6.6
179
1195
L15
ICPC
Knee symptom/complaint
1.3
6.6
525
4217
250, ,
Kela drug reimbursment
3.3
6.6
24
74
TGC00
NOMESCO Finland
Bronchial lavation
2.6
6.5
37
146
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.5
6.5
190
1288
AQ2
HP
Electrophysiological electroanatomical examination
6.8
6.5
15
22
G61.0
ICD-10 Finland
Guillain-Barré syndrome
70.0
6.4
7
*
E06.5
ICD-10 Finland
Other chronic thyroiditis
70.0
6.4
7
*
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
6.4
152
984
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.4
843
7195
WF002
NOMESCO Finland
Radical radiotherapy
1.8
6.4
84
463
S01KA02
ATC
hypromellose; ophthalmic
2.5
6.4
38
154
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
6.3
142
907
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.0
6.3
26
86
ZX100
NOMESCO Finland
Oral
3.0
6.3
26
86
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.1
6.3
60
296
XF602
NOMESCO Finland
Bloodpressure monitoring
3.1
6.3
25
81
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
6.3
47
211
2507B
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI I]
+∞
6.3
6
*
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
+∞
6.3
6
*
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
+∞
6.3
6
*
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
6.3
6
*
M13.9
ICD-10 Finland
Arthritis, unspecified
1.6
6.2
125
777
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
6.2
494
3962
L03
ICPC
Low back symptom/complaint
1.3
6.2
632
5232
R49.08
ICD-10 Finland
Other specified dysphonia
2.1
6.2
53
251
LCA06
NOMESCO Finland
Biopsy of endometrium
1.4
6.2
326
2462
SPAT1301
SPAT
No procedures
1.3
6.2
633
5242
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.5
6.2
37
150
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
1.8
6.2
83
461
S06
ICPC
Rash localized
1.7
6.2
103
610
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.2
6.1
47
213
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.8
6.1
18
48
N17
ICPC
Vertigo/dizziness
1.4
6.1
242
1745
L04AD01
ATC
ciclosporin; systemic
3.1
6.0
24
78
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
6.0
210
1476
Z29.9
ICD-10 Finland
Prophylactic measure, unspecified
3.2
6.0
23
73
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.8
6.0
82
458
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.5
6.0
159
1056

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
734
1317
7.27
307.65
1.5
1.1
231.13
82.26
iu/ml
13.82
407
426
1348
386
68.45
307.65
3.8
1.3
5.97
2.61
iu/l
9.55
899
95
1450
1069
28.00
307.65
7.9
2.7
4.78
4.53
pmol/l
5.49
1368
965
2614
17400
14.90
253.14
14.9
2.8
15.71
14.34
pmol/l
118.40
2530
15954
1657
9446
2.94
159.38
7.3
5.6
1.22
1.22
mmol/l
0.91
1431
8047
1506
8506
2.73
141.49
6.4
5.0
1.22
1.22
mmol/l
0.03
1410
7735
1839
11576
2.83
137.85
9.6
7.5
3.80
4.01
e9/l
4.35
1632
9969
2641
20834
11.22
136.19
16.2
3.6
1.71
2.17
mu/l
1.86
2549
19277
430
1325
3.67
117.39
3.1
3.0
62.97
79.90
ng/l
3.23
394
1140
1060
5517
2.51
110.64
5.1
3.5
7.40
7.40
ph
0.29
199
1022
1401
8457
2.36
102.68
2.6
2.0
75.89
76.74
nmol/l
0.56
1286
7657
2144
15771
2.72
98.75
8.7
6.1
78.16
76.38
u/l
1.31
2064
14783
1543
10079
2.23
88.86
6.1
4.2
0.19
0.19
e9/l
0.49
1373
8777
1408
8920
2.20
86.84
6.3
4.3
—
—
—
0
0
1425
9104
2.19
85.62
6.0
4.1
2.86
2.79
%
0.54
1338
8448
1489
9685
2.19
85.39
5.8
4.0
0.04
0.04
e9/l
0.36
1302
8249
1468
9516
2.18
84.66
6.0
4.1
28.61
28.91
%
0.53
1382
8893
1451
9367
2.18
84.51
5.8
4.0
56.40
56.57
%
0.22
1364
8734
1483
9658
2.18
84.43
5.8
4.0
0.55
0.55
e9/l
0.35
1302
8239
1426
9170
2.17
83.55
6.2
4.3
8.45
8.13
%
3.41
1338
8537
1379
8757
2.17
83.40
6.0
4.1
0.68
0.67
%
0.22
1289
8092
1518
10033
2.17
82.48
5.8
4.0
1.86
1.95
e9/l
2.25
1367
8816
73
56
13.37
76.92
1.6
1.7
15.78
13.77
pmol/l
1.76
65
48
1140
6945
2.11
74.30
3.1
3.3
2.34
2.36
mmol/l
8.07
1027
6182
2044
15778
2.20
66.96
4.4
3.0
12.15
10.96
mm/h
3.25
1924
14620
845
4906
2.05
59.88
1.4
1.2
1.85
1.13
u/ml
1.10
214
1304
864
5114
2.01
57.61
7.8
6.0
—
—
—
0
0
390
1731
2.46
52.88
2.1
2.1
376.22
379.35
nmol/l
0.12
362
1589
1580
11664
1.85
51.59
4.8
3.9
6.54
6.41
mmol/l
1.50
1487
10771
708
4065
2.00
50.33
1.5
1.3
2.14
2.24
g/l
1.08
422
2454
2550
22632
3.12
46.59
16.9
12.1
139.71
139.77
mmol/l
0.68
2499
22013
2553
22716
3.11
45.57
17.1
12.2
3.93
3.93
mmol/l
0.70
2501
22030
317
1405
2.42
42.67
2.2
1.3
—
—
—
0
0
474
2488
2.10
42.32
1.4
1.2
493.21
344.51
titre
1.43
112
390
1248
8919
1.74
42.20
11.0
7.2
0.00
0.00
e9/l
0.19
1034
7109
1149
8095
1.73
40.33
4.3
4.0
35.92
36.07
g/l
0.42
1068
7524
89
191
4.78
38.87
3.5
5.9
54.24
76.47
u/ml
0.24
29
52
721
4477
1.83
38.86
2.3
2.0
2.80
2.88
mg/l
0.48
636
3796
1324
9810
1.68
37.70
3.3
2.6
102.43
96.02
ug/l
0.48
1249
9212
1097
7776
1.69
36.62
2.0
1.8
98.45
97.85
pmol/l
0.13
572
3798
505
2905
1.91
34.10
3.4
3.2
0.81
0.82
mmol/l
1.12
474
2723
1369
10424
1.63
33.56
5.7
5.8
10.73
10.75
umol/l
0.01
1309
9869
400
2154
2.01
32.68
4.8
4.6
1.07
1.03
mmol/l
1.93
364
1989
2605
24010
3.15
32.50
13.3
7.9
24.41
24.82
u/l
0.66
2559
23175
2485
22407
2.30
32.48
14.9
10.6
19.13
22.53
mg/l
6.14
2012
17064
700
4569
1.72
30.61
3.1
2.8
1273.03
1052.74
ng/l
0.72
599
3851
1136
8407
1.60
30.23
14.8
11.9
1.26
1.19
inr
1.87
365
2429
1798
14897
1.61
29.13
4.0
3.2
—
—
—
0
0
116
370
3.23
29.11
2.2
2.6
—
—
—
0
0
2254
19892
1.79
27.72
5.8
4.6
39.44
38.20
mmol/mol
8.07
2111
18559
2578
23856
2.63
27.69
17.5
12.1
71.09
70.62
umol/l
0.34
2578
23847
340
1832
1.98
27.47
4.5
3.8
—
—
—
0
0
942
6882
1.57
25.25
2.2
2.1
—
—
—
0
0
249
1247
2.10
24.52
3.5
3.7
0.05
0.13
%
1.79
63
366
408
2418
1.81
24.41
2.5
2.1
2.44
2.41
g/l
0.45
377
2242
2215
19649
1.69
24.27
21.1
12.8
14.90
14.72
%
0.74
2192
19298
239
1186
2.11
24.10
3.5
3.7
0.02
0.62
%
0.96
54
311
256
1304
2.06
24.08
3.5
3.6
1.17
0.99
%
0.31
68
422
575
3765
1.67
24.06
1.3
1.2
27.38
19.25
iu/ml
0.78
170
1141
961
7125
1.54
23.76
3.7
3.0
42.77
37.35
ng/l
0.16
576
4157
548
3558
1.68
23.64
1.3
1.2
5.38
2.25
u/ml
1.18
188
1437
436
2671
1.75
23.22
2.5
2.1
13.64
13.84
umol/l
0.20
403
2493
231
1151
2.10
23.03
2.3
2.3
10.22
10.30
g/l
0.11
213
1039
849
6192
1.54
22.31
2.6
2.3
81.92
71.42
u/l
0.14
795
5723
372
2203
1.80
22.18
2.6
2.2
22.29
23.23
%
0.64
317
1892
232
1180
2.06
21.87
3.3
3.5
0.78
0.75
%
0.06
61
370
2553
23835
2.21
21.43
16.2
10.1
—
—
—
0
0
312
1794
1.84
20.42
1.2
1.1
—
—
—
0
0
1730
14741
1.48
20.27
4.7
3.7
—
—
—
0
0
760
5512
1.53
20.09
4.0
3.4
—
—
—
0
0
384
2384
1.71
19.26
2.0
1.3
133.31
78.98
ug/g
1.30
308
1794
712
5142
1.52
19.02
2.1
2.0
—
—
—
0
0
116
469
2.54
18.85
1.3
1.1
109.26
1.96
u/ml
—
7
18
1770
15262
1.46
18.64
3.2
2.8
41.47
40.58
u/l
0.17
1681
14365
2368
21742
1.70
18.59
4.6
4.0
5.85
5.73
mmol/l
4.59
2207
20079
599
4184
1.55
18.58
1.5
1.5
20.03
20.55
nmol/l
0.42
520
3557
265
1497
1.85
18.30
3.7
3.5
1.22
1.23
mmol/l
2.39
242
1295
906
6914
1.47
18.30
4.0
3.1
64.50
90.15
e6/l
1.05
630
4596
534
3653
1.58
18.11
2.8
2.8
2.44
2.45
mmol/l
0.29
453
3209
455
3014
1.61
17.64
1.7
1.6
1067.11
1161.28
nmol/l
1.70
367
2267
524
3591
1.57
17.58
3.9
3.2
229.89
300.30
ng/l
0.24
372
2431
1272
10413
1.42
17.22
2.5
2.4
—
—
—
0
0
51
135
3.83
17.08
4.9
7.6
—
—
—
0
0
100
397
2.58
16.90
1.3
1.1
38.62
2.26
u/ml
—
6
21
279
1646
1.77
16.66
2.6
2.2
1.66
1.74
%
0.69
252
1469
2656
25496
3.02
16.37
26.3
15.7
40.33
39.93
%
3.47
2533
24016
100
404
2.53
16.31
1.3
1.1
35.89
2.93
u/ml
—
10
43
898
6968
1.43
16.12
3.2
2.9
28.53
32.62
u/l
1.98
851
6644
196
1046
1.94
16.08
1.1
1.1
97.14
171.56
titre
—
7
16
176
908
2.00
15.92
1.8
1.7
1.26
1.43
g/l
0.85
163
820
526
3686
1.53
15.79
3.1
2.5
505.88
533.51
mosm/kgh2o
2.21
446
3122
749
5641
1.45
15.72
2.2
2.0
237.63
205.58
u/l
0.12
704
5308
2656
25531
2.95
15.65
26.4
15.7
262.86
259.82
e9/l
1.78
2611
24870
753
5682
1.45
15.62
3.5
2.7
23.78
93.29
e6/l
2.02
582
4155
1657
14332
1.40
15.60
4.8
4.0
1721.76
1701.07
e6/l
0.00
21
155
2657
25551
2.97
15.54
26.3
15.6
90.53
90.60
fl
0.38
2636
25210
2657
25552
2.96
15.52
26.4
15.7
6.58
6.60
e9/l
0.17
2606
24817
2657
25552
2.96
15.52
26.2
15.6
30.08
30.15
pg
1.32
2636
25211
240
1384
1.81
15.46
3.2
2.3
4.30
5.03
e9/l
0.56
204
1175
2657
25556
2.96
15.44
26.4
15.6
4.51
4.48
e12/l
3.35
2604
24839
101
421
2.45
15.43
1.6
1.2
0.22
0.25
g/l
1.88
93
399
93
374
2.54
15.33
1.2
1.1
47.05
14.80
u/ml
—
8
30
2657
25564
2.94
15.28
26.5
15.7
134.85
134.30
g/l
1.50
2638
25219
1170
9575
1.39
15.20
2.2
2.0
—
—
—
0
0
72
256
2.86
15.08
3.3
2.9
57.22
57.94
%
0.18
72
256
317
1999
1.66
14.81
1.3
1.2
—
—
—
0
0
536
3819
1.50
14.77
2.7
2.2
6.82
7.45
e6/l
0.43
482
3373
92
375
2.50
14.75
1.8
1.9
5.00
5.28
mmol/24h
0.37
76
331
662
4921
1.46
14.73
1.9
1.7
0.90
0.99
mg/l
0.58
480
3717
139
679
2.10
14.59
1.3
1.1
0.36
0.94
u/ml
—
9
61
123
574
2.20
14.50
1.3
1.2
—
—
—
0
0
694
5222
1.44
14.43
3.4
2.6
0.27
0.41
e6/l
1.39
527
3797
41
105
3.95
14.41
1.1
1.1
0.82
0.10
nmol/l
—
10
14
716
5444
1.43
13.99
3.3
2.8
6.98
7.36
mmol/l
1.57
615
4623
67
240
2.84
13.87
1.7
1.5
—
—
—
0
0
689
5210
1.43
13.86
4.1
3.3
92.30
94.79
%
1.80
673
5087
101
445
2.32
13.67
1.6
1.2
1.16
1.23
g/l
1.44
92
420
212
1223
1.80
13.62
2.3
2.8
65.40
67.03
g/l
2.58
195
1112
229
1354
1.76
13.53
3.0
2.7
194.53
156.01
ng/l
0.89
206
1223
406
2788
1.54
13.19
1.2
1.2
—
—
—
0
0
674
5124
1.42
13.04
4.0
3.3
8.06
7.33
mg/mmol
0.15
405
3038
643
4855
1.43
12.90
3.5
2.8
427.01
254.67
mg/l
0.41
403
2890
677
5166
1.41
12.78
3.3
2.6
—
—
—
0
0
202
1182
1.77
12.37
2.2
2.2
71.95
70.47
e9/l
0.19
145
886
347
2333
1.56
12.36
1.5
1.6
—
—
—
0
0
241
1495
1.67
11.94
1.3
1.5
—
—
—
0
0
637
4873
1.40
11.71
2.4
2.2
4985.14
4667.24
umol/l
0.06
559
4323
498
3654
1.44
11.54
1.6
1.6
—
—
—
0
0
1221
10363
1.32
11.34
3.6
3.2
0.00
0.00
estimate
1.47
251
1837
73
304
2.44
11.26
2.0
1.5
5765.93
9612.59
e6/l
1.21
56
220
56
205
2.77
11.20
2.2
1.5
—
—
—
0
0
339
2316
1.53
11.19
2.9
2.6
7.70
7.25
umol/l
0.14
293
1975
2380
22400
1.51
11.00
4.3
3.9
4.77
4.85
mmol/l
3.74
2234
21042
1219
10382
1.32
10.89
5.0
4.3
0.00
0.00
estimate
0.80
250
1732
65
261
2.53
10.84
1.5
1.6
0.74
0.76
g/l
0.05
48
197
601
4611
1.39
10.74
4.2
3.9
—
—
—
0
0
1227
10476
1.31
10.70
3.7
3.2
0.00
0.01
estimate
1.32
241
1721
109
552
2.02
10.45
2.8
3.0
—
—
—
0
0
2284
21389
1.43
10.21
3.8
3.5
1.25
1.25
mmol/l
0.02
2120
19865
2401
22720
1.50
9.95
4.8
4.2
2.86
2.90
mmol/l
1.47
2232
21212
2361
22273
1.46
9.89
4.3
3.8
1.51
1.54
mmol/l
3.08
2208
20826
412
3014
1.43
9.58
3.1
2.4
4.13
3.71
e6/l
0.27
226
1527
165
985
1.72
9.45
2.3
2.5
—
—
—
0
0
277
1884
1.52
9.30
7.0
6.7
5.11
5.10
kpa
0.07
266
1801
277
1884
1.52
9.30
6.9
6.7
12.23
13.24
kpa
2.44
268
1801
94
473
2.02
9.22
2.4
2.2
9.80
11.96
mg/l
1.54
87
441
276
1885
1.52
9.09
6.8
6.7
0.88
1.05
mmol/l
0.28
218
1490
164
995
1.69
8.86
6.0
6.5
24.91
24.78
mmol/l
0.18
164
990
112
609
1.88
8.78
1.8
1.5
1.44
1.54
g/l
0.55
93
526
689
5550
1.32
8.73
1.7
1.6
1.33
1.37
mmol/l
0.48
582
4761
118
654
1.84
8.71
1.1
1.1
3.85
3.27
u/ml
0.09
11
87
218
1441
1.56
8.33
3.2
3.0
1.87
1.92
mmol/l
0.06
166
1237
240
1625
1.52
8.23
7.2
7.3
95.27
96.10
%
1.18
229
1562
13
9
14.50
8.20
1.1
1.0
—
—
—
0
0
40
146
2.77
8.13
1.6
1.4
46.13
63.73
%
1.80
30
92
88
457
1.96
7.94
1.2
1.2
72.00
128.33
titre
—
5
42
565
4482
1.33
7.86
1.8
1.9
—
—
—
0
0
161
1004
1.64
7.86
2.9
3.3
5.24
5.18
kpa
0.31
155
958
351
2584
1.41
7.82
2.1
1.8
—
—
—
0
0
420
3187
1.38
7.81
2.9
2.3
1.35
1.33
e6/l
0.02
230
1685
215
1443
1.53
7.68
3.2
3.0
5.81
5.82
kpa
0.07
202
1402
159
995
1.64
7.66
2.8
3.3
7.43
7.41
ph
0.91
23
125
125
737
1.73
7.54
3.4
3.3
24.39
24.23
mmol/l
0.22
125
727
53
231
2.32
7.50
2.5
1.3
59.23
38.33
mu/l
0.88
47
209
216
1465
1.52
7.36
6.4
6.3
1.35
1.30
mmol/l
0.19
208
1432
248
1732
1.48
7.32
2.2
2.0
0.21
0.22
g/l
0.52
232
1634
61
286
2.16
7.27
4.1
3.1
0.79
0.79
nmol/l
0.05
52
230
44
180
2.47
7.17
1.3
1.2
—
—
—
0
0
695
5734
1.29
7.15
3.7
2.8
—
—
—
0
0
106
609
1.77
7.01
1.2
1.2
—
—
—
0
0
33
118
2.82
7.00
1.1
1.1
—
—
—
0
0
237
1656
1.47
6.99
3.9
3.4
—
—
—
0
0
72
368
1.98
6.85
1.3
1.3
—
—
—
0
0
68
341
2.02
6.82
1.3
1.3
179.38
104.84
u/ml
0.54
18
79
304
2242
1.40
6.68
2.0
1.6
—
—
—
0
0
222
1549
1.47
6.60
7.7
7.5
122.25
121.45
g/l
0.24
215
1499
41
171
2.42
6.44
1.4
1.4
—
—
—
0
0
500
4005
1.30
6.38
1.7
1.5
62791121.79
53905759.17
pmol/l
0.10
430
3380
326
2463
1.37
6.19
4.4
4.1
32.33
32.60
%
0.18
244
1672
92
527
1.77
6.19
2.0
2.3
282.93
1007.94
ug/l
1.07
82
491
761
6452
1.25
6.08
3.0
2.8
—
—
—
0
0
40
170
2.37
6.05
1.4
1.4
0.32
0.41
g/l
1.59
25
120
40
170
2.37
6.05
1.4
1.4
2.80
2.90
g/l
0.14
24
121
40
170
2.37
6.05
1.4
1.4
6.31
6.52
g/l
0.22
25
120
191
1322
1.48
5.93
7.5
6.4
9.13
8.53
mmol/l
0.58
182
1262
47
221
2.15
5.64
2.0
1.4
—
—
—
0
0
47
222
2.14
5.58
1.5
1.1
—
—
—
0
0
16
42
3.83
5.53
1.1
1.1
—
—
—
0
0
40
178
2.27
5.49
1.0
1.1
—
—
—
0
0
90
532
1.72
5.47
1.4
1.3
291.52
303.20
ug/g
0.22
55
284
134
877
1.56
5.44
7.8
9.2
—
—
—
0
0
81
466
1.76
5.41
2.0
2.5
38.26
38.45
g/l
0.12
76
416
261
1945
1.38
5.40
2.9
2.1
39.40
35.40
u/l
0.26
222
1654
96
581
1.68
5.36
3.1
3.2
0.24
0.22
g/l
0.10
43
210
28
107
2.63
5.31
1.4
1.3
43.41
29.03
%
0.87
18
62
9
8
11.28
5.29
10.1
18.5
5.46
4.63
mmol/l
—
9
8
189
1341
1.44
5.19
8.4
7.5
—
—
—
0
0
30
121
2.50
5.12
1.3
1.2
—
—
—
0
0
952
8389
1.21
5.05
3.2
3.0
6.03
5.90
ph
0.64
79
802
130
863
1.53
4.97
2.8
2.3
0.27
0.26
e6/l
0.04
124
829
301
2329
1.33
4.89
1.4
1.4
—
—
—
0
0
65
363
1.81
4.83
1.9
2.2
132.48
129.87
g/l
0.39
44
261
118
772
1.55
4.83
1.1
1.1
—
—
—
0
0
193
1395
1.41
4.80
2.2
2.2
10.19
6.18
ug/l
0.65
155
1226
61
335
1.84
4.79
3.1
3.0
—
—
—
0
0
112
726
1.57
4.78
2.8
3.4
—
—
—
0
0
202
1475
1.40
4.74
2.3
2.3
19.53
24.38
au/ml
0.29
11
148
29
120
2.43
4.71
1.2
1.1
101.43
88.18
titre
—
7
11
193
1400
1.41
4.71
3.4
2.5
—
—
—
0
0
56
303
1.87
4.62
2.5
2.2
41.04
85.81
ug/min
0.60
35
175
371
2979
1.28
4.59
1.2
1.2
—
—
—
0
0
89
552
1.63
4.57
2.4
2.3
—
—
—
0
0
33
147
2.26
4.57
3.0
3.8
—
—
—
0
0
27
110
2.47
4.54
1.4
1.2
32169.61
165552.96
e6/l
0.88
18
81
52
277
1.89
4.50
1.3
1.3
72.10
61.16
mmol/l
0.85
42
217
756
6579
1.21
4.47
1.5
1.5
—
—
—
0
0
27
112
2.42
4.38
1.1
1.1
—
—
—
0
0
216
1617
1.36
4.38
1.5
1.3
25.40
30.70
iu/l
1.88
185
1419
15
45
3.35
4.32
3.7
2.5
—
—
—
0
0
66
384
1.74
4.31
3.2
2.9
25.52
24.75
mmol/l
0.58
66
375
183
1339
1.39
4.27
1.2
1.3
47.45
46.87
au/ml
—
6
86
61
348
1.77
4.27
2.7
2.5
—
—
—
0
0
131
903
1.47
4.23
1.7
1.8
—
—
—
0
0
34
159
2.15
4.21
1.3
1.2
—
—
—
0
0
279
2186
1.31
4.16
1.4
1.4
—
—
—
0
0
69
411
1.70
4.16
1.7
1.5
44.94
32.41
e6/l
0.21
53
315
69
411
1.70
4.16
1.7
1.5
835.74
2112.29
e6/l
0.79
57
332
59
337
1.77
4.12
1.2
1.2
299.84
236.99
u/ml
0.97
37
215
98
641
1.55
4.07
2.7
3.5
25.17
24.94
mmol/l
0.29
90
593
60
349
1.74
3.95
3.6
3.4
8.81
8.78
kpa
0.04
60
344
42
219
1.93
3.92
2.7
3.3
0.86
1.56
%
1.32
36
196
65
388
1.69
3.91
1.7
1.5
—
—
—
0
0
142
1014
1.42
3.84
2.6
2.3
—
—
—
0
0
24
101
2.39
3.81
3.0
2.8
—
—
—
0
0
617
5341
1.20
3.79
4.0
3.4
0.00
0.01
estimate
1.98
243
1710
38
194
1.97
3.77
2.0
1.6
—
—
—
0
0
59
347
1.72
3.76
3.5
3.4
2.55
2.48
mmol/l
0.08
45
220
59
347
1.72
3.76
3.5
3.4
4.93
5.00
kpa
0.33
59
342
159
1163
1.39
3.75
2.3
2.1
4986.91
6017.98
u/l
0.17
70
468
28
128
2.20
3.70
2.3
3.0
60.09
58.27
%
0.20
23
112
53
305
1.75
3.65
1.3
1.2
2.65
4.86
u/ml
1.08
26
113
61
367
1.68
3.59
1.1
1.0
2.67
2.07
u/ml
0.27
23
188
44
241
1.84
3.57
1.2
1.3
—
—
nmol/l
—
0
0
18
68
2.66
3.56
1.1
1.1
—
—
—
0
0
33
164
2.02
3.54
1.3
1.1
0.40
1.22
u/ml
0.80
21
90
12
31
3.88
3.48
4.0
4.4
—
—
—
0
0
15
52
2.90
3.46
1.0
1.4
—
—
—
0
0
20
81
2.48
3.46
1.1
1.4
150.30
143.25
mmol/24h
0.16
20
81
23
100
2.31
3.43
1.5
1.4
37.53
26.27
umol/l
0.68
23
94
86
570
1.53
3.42
2.1
1.9
0.47
1.53
ug/l
2.03
71
510
142
1037
1.39
3.41
8.4
8.3
1.36
1.37
%
0.04
142
1032
51
297
1.73
3.39
1.5
1.4
—
—
—
0
0
72
462
1.57
3.31
1.6
1.3
487.62
501.10
mg/l
0.11
66
439
64
400
1.61
3.28
1.1
1.2
—
—
—
0
0
31
156
2.00
3.24
2.1
2.2
—
—
—
0
0
56
340
1.66
3.22
2.3
2.3
16.64
16.33
%
0.22
29
167
40
222
1.81
3.15
1.2
1.2
—
—
—
0
0
160
1208
1.34
3.14
2.8
2.6
4.84
4.56
kpa
0.77
150
1172
21
93
2.27
3.03
1.8
1.3
4.84
5.54
u/l
0.40
16
76
140
1043
1.36
3.01
8.9
8.4
94.27
94.18
%
0.07
140
1038
12
37
3.25
2.93
1.2
1.3
69.86
79.71
ng/l
0.20
12
37
331
2766
1.22
2.91
2.4
2.0
30.34
29.40
s
1.53
317
2679
56
350
1.61
2.91
2.2
2.3
4.43
4.58
umol/l
0.09
37
252
47
283
1.67
2.83
2.9
2.6
—
—
—
0
0
42
246
1.72
2.79
1.3
1.3
—
—
—
0
0
17
72
2.37
2.72
1.5
2.4
—
—
—
0
0
109
797
1.38
2.67
1.1
1.2
—
—
—
0
0
87
612
1.44
2.65
1.4
1.3
11.94
12.15
u/l
0.04
75
510
127
953
1.35
2.65
1.6
1.6
261.94
304.23
mu/l
1.60
110
861
139
1058
1.33
2.63
4.6
4.5
—
—
—
0
0
25
127
1.98
2.60
1.4
1.1
44.65
35.64
mg/l
0.52
19
110
236
1930
1.24
2.56
1.5
1.4
—
—
—
0
0
79
553
1.44
2.49
5.9
5.4
1.21
1.23
mmol/l
0.09
73
482
86
612
1.42
2.48
1.1
1.1
—
—
—
0
0
42
256
1.65
2.45
2.2
1.7
1.54
1.67
mmol/l
0.56
42
251
541
4799
1.16
2.42
3.1
3.1
—
—
—
0
0
16
70
2.29
2.41
1.8
1.3
—
—
—
0
0
15
64
2.35
2.38
1.1
1.0
1394.73
1379.83
miu/ml
0.02
15
64
67
463
1.46
2.28
3.2
3.5
31.56
61.80
mg/l
1.14
48
381
23
120
1.92
2.25
1.2
1.1
286.00
244.97
mg/l
0.42
17
107
48
311
1.55
2.22
1.2
1.7
—
—
—
0
0
136
1726
0.78
2.20
1.4
1.4
—
—
—
0
0
195
1592
1.24
2.18
1.2
1.2
—
—
—
0
0
130
1010
1.30
2.18
6.4
6.5
24.55
24.56
mmol/l
0.01
123
949
19
94
2.03
2.16
1.1
1.4
118.89
134.70
nmol/l
0.85
19
94
66
461
1.44
2.15
1.7
1.7
—
—
—
0
0
9
30
3.01
2.14
1.0
1.0
—
—
—
0
0
9
30
3.01
2.14
1.0
1.0
—
—
—
0
0
9
30
3.01
2.14
1.0
1.0
—
—
—
0
0
72
512
1.42
2.13
1.1
1.1
—
—
—
0
0
66
465
1.43
2.06
3.3
3.5
25.70
58.95
mg/l
1.22
47
382
129
1012
1.29
2.03
3.2
2.7
132.12
130.13
g/l
0.47
122
986
17
83
2.05
2.01
1.1
1.1
160.04
169.89
iu/ml
0.09
17
83
232
2744
0.83
1.98
1.3
1.3
—
—
—
0
0
16
77
2.08
1.96
1.2
1.2
—
—
—
0
0
17
84
2.03
1.95
2.1
2.3
44.63
42.11
%
—
8
43
19
98
1.95
1.95
2.0
1.5
—
—
—
0
0
14
64
2.19
1.94
3.1
7.3
92.44
75.50
mg/l
—
9
36
179
1470
1.23
1.93
1.5
1.2
183.78
174.35
u/ml
0.09
170
1358
16
78
2.06
1.90
1.9
3.3
7.44
7.43
ph
—
7
26
133
1058
1.27
1.90
1.4
1.4
—
—
—
0
0
23
129
1.79
1.85
1.7
1.2
—
—
—
0
0
11
46
2.40
1.85
46.2
34.9
6.85
7.90
ug/l
0.69
11
40
6
17
3.53
1.83
1.3
1.2
—
—
—
0
0
50
344
1.46
1.80
1.1
1.2
—
—
—
0
0
65
473
1.38
1.74
1.4
1.3
29.21
26.70
u/l
0.22
51
392
9
36
2.50
1.74
1.8
1.5
—
—
—
0
0
12
55
2.19
1.67
1.0
1.0
—
—
—
0
0
88
676
1.31
1.67
2.6
3.4
201.85
2303.39
u/ml
0.82
69
589
49
342
1.44
1.66
2.1
3.0
31.05
34.72
umol/l
0.79
43
311
14
69
2.03
1.64
2.6
2.4
—
—
—
0
0
10
41
2.44
1.64
1.4
1.1
—
—
—
0
0
28
173
1.62
1.64
1.3
1.3
1016.73
1920.78
e6/l
1.71
22
122
12
56
2.15
1.61
1.8
1.8
—
—
—
0
0
42
287
1.47
1.60
2.1
1.7
—
—
—
0
0
32
206
1.56
1.59
2.1
1.5
—
—
—
0
0
6
20
3.00
1.58
1.0
1.2
—
—
—
0
0
21
122
1.73
1.54
1.0
1.0
—
—
—
0
0
172
1445
1.20
1.53
1.5
1.4
—
—
—
0
0
27
169
1.60
1.52
1.1
1.1
365.59
386.94
nmol/l
0.21
22
155
23
138
1.67
1.51
1.7
1.9
12.43
10.61
%
1.08
23
138
29
185
1.57
1.51
1.6
1.5
276.10
279.08
mosm/kgh2o
0.23
20
143
21
123
1.71
1.50
3.2
3.2
—
—
—
0
0
16
86
1.87
1.50
1.3
1.6
1.77
1.96
umol/l
0.60
16
79
121
984
1.24
1.49
3.2
3.1
—
—
—
0
0
14
72
1.95
1.48
1.2
1.2
—
—
—
0
0
149
1239
1.21
1.48
1.3
1.2
—
—
—
0
0
24
147
1.64
1.47
1.3
1.3
—
—
—
0
0
197
1684
1.18
1.46
2.8
3.4
71.84
51.88
u/ml
0.40
190
1627
308
2726
1.15
1.46
1.6
1.7
—
—
—
0
0
15
80
1.88
1.44
1.5
2.9
195.88
192.68
umol/l
—
8
40
54
728
0.74
1.44
14.4
7.1
—
—
—
0
0
9
40
2.25
1.40
1.9
1.5
—
—
—
0
0
95
758
1.26
1.39
2.8
2.7
25.07
25.47
mmol/l
0.55
87
732
98
785
1.26
1.39
2.3
1.9
21.86
21.35
s
0.21
91
664
14
74
1.90
1.39
1.0
1.0
—
—
—
0
0
25
158
1.59
1.37
1.3
1.3
19369.79
65212.78
e6/l
0.75
19
86
6
23
2.61
1.36
1.3
1.4
5.47
1564712.54
nmol/l
—
6
17
299
2656
1.14
1.36
4.4
4.6
2.29
2.42
ug/l
0.17
260
2379
181
1554
1.18
1.30
2.7
2.9
0.79
0.74
ug/l
0.41
106
973
8
35
2.29
1.26
1.0
2.0
—
—
—
0
0
25
162
1.55
1.25
3.4
2.5
—
—
—
0
0
46
337
1.37
1.25
3.7
3.6
—
—
—
0
0
82
653
1.26
1.25
6.0
4.7
0.83
0.91
%
0.74
77
601
13
70
1.86
1.24
1.7
1.5
131.23
82.58
nmol/24h
0.34
13
70
24
155
1.55
1.23
2.1
1.6
6.76
6.31
mmol/l
0.33
19
106
12
63
1.91
1.22
2.1
2.0
—
—
—
0
0
82
656
1.26
1.21
1.4
1.3
—
—
—
0
0
237
2093
1.15
1.19
3.3
4.0
9.91
37.59
ug/l
0.97
180
1633
32
222
1.45
1.19
1.8
1.7
—
1485.71
—
0
7
42
308
1.37
1.15
1.2
1.1
—
—
—
0
0
15
87
1.73
1.15
1.3
1.2
—
—
—
0
0
19
118
1.61
1.14
1.0
1.0
—
—
—
0
0
301
2712
1.12
1.12
1.5
1.4
—
—
—
0
0
97
799
1.22
1.12
1.9
2.0
10.18
10.87
nmol/l
0.30
84
722
108
902
1.21
1.09
1.5
1.7
—
—
—
0
0
28
193
1.46
1.09
3.1
3.0
—
—
—
0
0
8
41
1.95
1.08
1.0
1.0
—
—
—
0
0
7
32
2.19
1.08
2.0
1.3
—
—
—
0
0
11
59
1.87
1.07
1.7
2.1
—
—
—
0
0
7
35
2.00
1.00
6.1
7.0
—
—
—
0
0
17
107
1.59
0.99
13.7
13.2
0.69
0.60
mmol/l
1.12
17
99
27
189
1.43
0.99
1.9
1.9
—
—
—
0
0
22
148
1.49
0.98
1.4
1.2
—
—
—
0
0
15
92
1.63
0.97
2.7
2.3
795.40
740.13
e6/l
0.16
15
87
21
141
1.49
0.94
1.0
1.0
—
—
—
0
0
53
417
1.28
0.94
1.4
1.4
2.42
3.85
ug/l
1.38
47
376
6
27
2.22
0.93
1.0
1.0
—
—
—
0
0
23
159
1.45
0.91
1.3
1.1
—
—
—
0
0
6
29
2.07
0.89
7.0
6.0
—
—
—
0
0
73
602
1.22
0.88
1.1
1.1
—
—
—
0
0
11
64
1.72
0.86
1.1
1.1
—
—
—
0
0
6
31
1.94
0.84
1.0
1.3
—
—
—
0
0
2045
20098
1.07
0.83
22.1
13.5
331.59
331.93
g/l
1.04
2034
19949
8
138
0.58
0.83
1.0
1.2
—
—
—
0
0
8
46
1.74
0.82
1.6
1.3
17.01
17.22
umol/l
—
8
40
21
146
1.44
0.82
1.2
1.1
1.02
1.05
ratio
—
9
52
11
65
1.70
0.82
1.3
2.5
—
—
—
0
0
8
47
1.70
0.80
1.3
1.3
—
—
—
0
0
48
383
1.26
0.79
1.1
1.4
—
—
—
0
0
36
277
1.30
0.79
1.1
1.1
69.68
3.81
iu/ml
—
5
59
27
199
1.36
0.78
1.1
1.1
—
—
—
0
0
48
386
1.25
0.75
1.1
1.1
—
—
—
0
0
56
460
1.22
0.73
4.4
4.1
—
—
—
0
0
18
125
1.44
0.72
1.6
1.4
—
—
—
0
0
7
42
1.67
0.68
1.0
1.2
—
—
—
0
0
53
438
1.21
0.67
3.6
3.0
21.11
25.98
mg/l
0.44
24
255
31
240
1.30
0.67
1.9
2.6
—
—
—
0
0
312
2904
1.08
0.67
1.9
1.8
—
—
—
0
0
27
205
1.32
0.67
2.0
2.9
—
—
—
0
0
21
154
1.37
0.65
2.2
2.6
44.27
21.45
mg/l
0.38
12
107
57
477
1.20
0.64
1.8
1.4
0.42
0.43
nmol/l
0.09
45
388
47
386
1.22
0.64
1.1
1.1
—
—
—
0
0
476
4510
1.07
0.64
4.1
3.4
1.02
1.02
kg/l
0.02
90
686
5
30
1.67
0.61
1.6
1.8
—
—
—
0
0
19
140
1.36
0.58
1.5
1.4
—
—
—
0
0
87
763
1.14
0.58
1.4
1.5
—
—
—
0
0
53
447
1.19
0.57
1.1
1.1
2.28
1.72
u/ml
0.17
26
189
42
347
1.21
0.56
2.6
1.7
0.85
0.85
nmol/l
0.02
32
304
27
212
1.28
0.55
1.1
1.2
—
—
—
0
0
901
8730
1.05
0.55
2.6
2.4
—
—
—
0
0
11
74
1.49
0.53
1.1
10.2
—
—
—
0
0
22
172
1.28
0.48
1.0
1.0
0.27
1.82
u/ml
—
9
49
17
128
1.33
0.47
1.2
1.5
69.88
72.73
umol/l
0.34
17
128
37
309
1.20
0.47
1.1
1.1
—
—
—
0
0
20
155
1.29
0.46
1.2
1.2
—
—
—
0
0
83
740
1.13
0.46
1.4
1.4
—
—
—
0
0
91
818
1.12
0.45
1.4
1.9
—
—
—
0
0
7
50
1.40
0.45
1.0
1.2
—
—
—
0
0
83
744
1.12
0.43
1.4
1.4
—
—
—
0
0
5
31
1.61
0.43
1.2
2.0
—
—
—
0
0
53
462
1.15
0.42
1.0
1.1
0.41
1.28
u/ml
1.52
24
175
5
33
1.52
0.41
1.2
1.1
0.01
0.05
u/ml
—
5
33
0
15
0.00
0.41
0.0
10.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.11
—
0
8
21
168
1.25
0.40
1.6
1.5
—
—
—
0
0
10
71
1.41
0.39
1.0
1.1
1982.00
587.67
ng/l
—
5
12
99
908
1.09
0.36
1.4
1.9
—
—
—
0
0
98
899
1.09
0.35
1.4
1.8
—
—
—
0
0
5
79
0.63
0.35
3.8
1.6
—
—
—
0
0
9
122
0.74
0.35
1.2
1.2
—
—
—
0
0
99
911
1.09
0.34
1.4
1.9
—
—
—
0
0
76
691
1.10
0.33
1.5
1.8
—
—
—
0
0
60
539
1.12
0.33
1.1
1.1
3.41
2.28
u/ml
0.22
31
257
54
482
1.12
0.33
1.0
1.1
2.04
5.44
u/ml
2.96
30
232
66
729
0.90
0.33
1.3
1.3
—
—
—
0
0
104
964
1.08
0.31
1.1
1.1
—
—
—
0
0
99
916
1.08
0.31
1.4
1.9
—
—
—
0
0
100
926
1.08
0.31
1.2
1.3
213.44
222.15
miu/ml
0.10
57
481
7
55
1.27
0.30
1.1
1.2
—
—
—
0
0
27
231
1.17
0.29
1.2
1.3
—
—
—
0
0
12
152
0.79
0.29
2.9
2.1
—
—
—
0
0
8
110
0.73
0.28
1.3
1.2
218.00
337.89
u/l
—
8
100
51
459
1.11
0.28
1.2
1.2
—
—
—
0
0
83
768
1.08
0.27
1.4
1.5
195.91
139.47
pmol/l
0.20
83
754
58
636
0.91
0.27
1.8
2.6
—
—
—
0
0
17
142
1.20
0.24
1.9
2.5
0.46
1.15
g/24h
—
6
65
0
11
0.00
0.21
0.0
1.1
—
0.25
—
0
5
0
10
0.00
0.21
0.0
1.6
—
14.32
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
0.09
—
0
8
0
13
0.00
0.21
0.0
1.1
—
0.06
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.11
—
0
9
7
58
1.21
0.18
2.0
1.6
—
—
—
0
0
7
59
1.19
0.18
1.1
1.2
—
—
—
0
0
15
129
1.16
0.17
1.1
1.5
1.71
1.56
nmol/l
—
10
120
6
76
0.79
0.15
1.2
1.5
228.00
156.07
pmol/l
—
6
76
11
93
1.18
0.14
3.5
1.5
1.00
3.28
u/field
—
6
66
27
246
1.10
0.14
2.4
2.5
—
—
—
0
0
17
151
1.13
0.13
1.2
1.1
—
—
—
0
0
23
252
0.91
0.12
1.1
1.0
—
—
—
0
0
13
147
0.88
0.11
1.1
1.3
—
—
—
0
0
16
144
1.11
0.10
1.3
1.6
1.31
1.34
promille
0.02
11
109
57
545
1.05
0.10
3.2
2.4
—
—
—
0
0
5
46
1.09
0.09
1.2
1.2
128.42
105.76
nmol/l
—
5
32
5
62
0.81
0.08
1.0
1.8
—
—
—
0
0
5
63
0.79
0.08
1.8
1.8
—
—
—
0
0
20
185
1.08
0.08
1.5
1.6
—
—
—
0
0
7
65
1.08
0.08
2.4
1.6
—
—
—
0
0
18
195
0.92
0.08
1.1
1.3
—
—
—
0
0
11
98
1.12
0.07
3.7
2.4
20.74
18.69
ug/l
0.23
11
89
7
84
0.83
0.07
1.6
1.5
—
—
—
0
0
28
265
1.06
0.07
1.5
1.7
—
—
—
0
0
9
103
0.87
0.06
1.2
1.2
—
—
—
0
0
151
1487
1.02
0.05
3.6
2.8
—
—
—
0
0
19
200
0.95
0.03
3.3
2.2
—
—
—
0
0
16
168
0.95
0.02
1.0
1.0
0.11
0.25
u/ml
—
5
38
39
381
1.02
0.02
1.1
1.1
0.40
4.78
u/ml
4.81
16
141
40
409
0.98
0.02
1.0
1.1
0.96
3.80
u/ml
2.92
15
177
10
93
1.08
0.02
1.2
1.6
—
—
—
0
0
39
395
0.99
0.00
1.5
2.4
—
—
—
0
0
66
661
1.00
0.00
4.2
4.2
—
—
—
0
0
16
164
0.98
0.00
1.1
1.3
1.48
1.59
g/l
0.71
16
164
10
102
0.98
0.00
1.2
1.1
—
—
—
0
0
13
128
1.02
0.00
1.2
1.3
—
—
—
0
0
18
182
0.99
0.00
1.5
1.3
0.84
0.95
g/l
1.21
18
182
31
312
0.99
0.00
1.1
1.1
—
—
—
0
0
34
338
1.01
0.00
1.1
1.1
0.17
0.32
u/ml
0.49
13
80
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
2.6
3.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
275.71
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
13.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
61.14
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.84
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
72
0.97
-0.00
1.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AUTOIMMUNE_HYPERTHYROIDISM and mortality.

Females

Parameter HR [95% CI] p-value
AUTOIMMUNE_HYPERTHYROIDISM 1.083 [0.97, 1.21] 0.162
Birth year 0.998 [0.99, 1.01] 0.617

During the follow-up period (1.1.1998 — 31.12.2019), 1133 out of 10957 females with AUTOIMMUNE_HYPERTHYROIDISM died.

Males

Parameter HR [95% CI] p-value
AUTOIMMUNE_HYPERTHYROIDISM 1.223 [1.05, 1.42] 0.008
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 392 out of 2528 males with AUTOIMMUNE_HYPERTHYROIDISM died.

Mortality risk

Mortality risk for people of age

years, who have AUTOIMMUNE_HYPERTHYROIDISM.

N-year risk Females Males
1 0.117% 0.217%
5 0.744% 1.299%
10 1.652% 3.238%
15 3.454% 6.115%
20 6.064% 10.044%

Relationships between endpoints

Index endpoint: AUTOIMMUNE_HYPERTHYROIDISM – Autoimmune hyperthyroidism

GWS hits: 15

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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