-
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
664 |
4. Check minimum number of eventsNone |
664 |
5. Include endpointsNone |
664 |
6. Filter based on genotype QC (FinnGen only) |
664 |
Control definitions (FinnGen only)
- Control exclude
- E4_NUTRIDEF
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E50-E64
- Name in latin
- Deficientia vitamini D
Similar endpoints
↥List of similar endpoints to
Vitamin D deficiency
based on the number of shared cases.
Similar with more cases:
- Vitamin deficiency
- Vitamin deficiency, wide
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5671 | 3233 | 2399 |
| Only index persons | 5177 | 2942 | 2235 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.09 | 0.07 |
| Only index persons | 0.10 | 0.11 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 44.36 | 48.89 | 38.37 |
| Only index persons | 43.19 | 47.31 | 37.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 664 | 435 | 229 |
| Unadjusted period prevalence (%) | 0.13 | 0.15 | 0.10 |
| Median age at first event (years) | 47.42 | 45.20 | 51.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 598
- Matched controls
- 5980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
11211.2
323.0
474
*
E66.01
ICD-10 Finland
Obesity due to excess calories
20.1
48.1
73
41
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.6
43.9
264
1064
E66.8
ICD-10 Finland
Other obesity
75.9
43.7
49
7
2680A
ICD-9 Finland
Vitamin D deficiency, Rickets, active
+∞
29.4
28
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
28.7
207
890
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
15.4
28.4
47
33
E55.0
ICD-10 Finland
Rickets, active
+∞
24.1
23
*
26500
ICD-8 Finland
Vitamin D deficiency, Rickets active
+∞
22.0
21
*
E66.9
ICD-10 Finland
Obesity, unspecified
23.4
20.6
29
13
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.6
20.5
101
321
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.3
20.2
55
95
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
6.9
20.1
51
80
E66.00
ICD-10 Finland
Metabolic syndrome
13.4
19.1
33
26
E55
ICD-10 Finland
Vitamin D deficiency
35.6
19.0
24
7
A11CC03
ATC
alfacalcidol; systemic
10.3
18.9
37
38
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
18.6
256
1492
E83.51
ICD-10 Finland
Hypocalcemia
26.0
18.4
25
10
L28
ICPC
Limited function/disability (L)
3.2
17.9
101
355
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
68.7
17.8
20
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.4
17.2
64
158
H03AA01
ATC
levothyroxine sodium; systemic
2.5
16.9
159
762
E83.39
ICD-10 Finland
Other disorder of phosphorus metabolism
174.6
16.6
17
*
R4190
NOMESCO Finland
Nutritional therapy
5.9
15.7
44
79
SPAT1301
SPAT
No procedures
2.1
14.7
208
1199
SPAT1229
SPAT
Assessment of need for aid
4.0
14.6
59
158
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
13.0
14.5
25
20
N06AX11
ATC
mirtazapine; oral
2.1
14.5
199
1132
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.0
14.4
90
336
T82
ICPC
Obesity
7.7
14.4
33
45
AA1AD
NOMESCO Finland
CT of head and brain
2.4
14.1
142
698
N03AX12
ATC
gabapentin; oral
2.7
14.0
105
440
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.8
14.0
60
169
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
13.7
102
424
A09AA02
ATC
multienzymes (lipase, protease etc.)
11.3
13.6
25
23
N05AH04
ATC
quetiapine; oral
2.5
13.6
121
557
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
13.4
171
934
N03AX16
ATC
pregabalin; oral
2.3
13.2
138
687
N02AX02
ATC
tramadol; systemic, rectal
2.0
12.9
230
1435
N06AX21
ATC
duloxetine; oral
2.9
12.9
81
302
SPAT1216
SPAT
Assessment of functional ability
2.7
12.8
92
374
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
12.8
253
1643
N02BE01
ATC
paracetamol; systemic, rectal
2.2
12.8
493
4093
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.9
12.4
82
315
A02BC02
ATC
pantoprazole; systemic
1.9
12.2
358
2657
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.8
12.2
30
46
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.1
227
1438
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
12.0
74
274
N06AB04
ATC
citalopram; systemic
2.2
12.0
137
710
C03CA01
ATC
furosemide; systemic
2.2
11.9
138
719
ZX120
NOMESCO Finland
Intravenous
3.0
11.9
72
263
N06AB10
ATC
escitalopram; oral
2.2
11.8
143
759
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.2
11.8
139
730
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.4
11.6
56
174
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
11.5
127
644
E83.30
ICD-10 Finland
Acid phosphatase deficiency
+∞
11.5
11
*
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
+∞
11.5
11
*
M25.5
ICD-10 Finland
Pain in joint
2.0
11.5
178
1044
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.4
11.5
105
486
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
11.3
65
230
N06AX16
ATC
venlafaxine; oral
2.5
11.2
97
437
SPAT1254
SPAT
Administration of medicine
2.4
11.2
102
473
N03AE01
ATC
clonazepam; systemic
3.9
11.1
46
126
M79.7
ICD-10 Finland
Fibromyalgia
5.1
11.0
34
70
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
11.0
64
229
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
44.2
11.0
13
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
10.8
94
423
M81.8
ICD-10 Finland
Other osteoporosis
28.6
10.8
14
5
A01
ICPC
Pain general/multiple sites
3.3
10.7
55
180
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
8.7
10.6
22
26
R51
ICD-10 Finland
Headache
3.6
10.6
47
137
R51.80
ICD-10 Finland
Headache
2.3
10.6
105
507
SPAT1263
SPAT
Sampling
1.8
10.5
253
1726
V03AG01
ATC
sodium cellulose phosphate; systemic
111.9
10.4
11
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.3
10.4
31
61
26599
ICD-8 Finland
Vitamin D deficiency, Unspecified
+∞
10.4
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
10.4
63
230
K02.1
ICD-10 Finland
Caries of dentine
1.8
10.2
345
2610
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
10.1
80
344
N06AB06
ATC
sertraline; oral
2.5
10.1
80
344
H02AB06
ATC
prednisolone; systemic
1.8
10.1
260
1803
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
10.0
87
392
M54.5
ICD-10 Finland
Low back pain
1.9
10.0
191
1200
G47.3
ICD-10 Finland
Sleep apnoea
2.3
9.9
102
500
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
9.9
257
1788
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
9.9
135
748
A04
ICPC
Weakness/tiredness general
2.4
9.8
90
415
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
9.8
250
1723
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.4
9.7
82
365
EBA15
NOMESCO Finland
Extraction of large number of teeth
5.4
9.6
28
54
-
ICD-10 Finland
NA
6.2
9.6
25
42
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
9.6
82
367
RD210
NOMESCO Finland
NA
7.7
9.5
21
28
N03AG01
ATC
valproic acid; systemic, rectal
3.2
9.5
49
162
E61.2
ICD-10 Finland
Magnesium deficiency
101.5
9.4
10
*
26510
ICD-8 Finland
Vitamin D deficiency, Rickets, late effect
+∞
9.4
9
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.2
9.4
35
88
SPAT1260
SPAT
Consultation of another employee
2.1
9.4
111
579
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
9.7
9.3
18
19
Z72.0
ICD-10 Finland
Tobacco use
5.6
9.3
26
48
SPAT1310
SPAT
Counselling related to known health issue
1.8
9.3
196
1269
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.3
9.3
85
394
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.5
9.2
76
332
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.3
9.2
27
53
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
9.2
110
578
D01
ICPC
Abdominal pain/cramps general
2.4
9.1
78
349
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
9.1
78
349
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
9.1
194
1261
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
9.0
182
1159
M79.6
ICD-10 Finland
Pain in limb
1.8
8.9
200
1317
C03DA01
ATC
spironolactone; oral
2.8
8.9
59
227
R11
ICD-10 Finland
Nausea and vomiting
2.8
8.9
57
218
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
8.8
45
148
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
8.7
52
190
E66.0
ICD-10 Finland
Obesity due to excess calories
50.7
8.7
10
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
50.7
8.7
10
*
B03BA03
ATC
hydroxocobalamin; parenteral
3.9
8.7
34
90
UJF32
NOMESCO Finland
Coloscopy
2.0
8.6
129
737
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.0
8.5
48
167
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.2
8.5
31
77
P01
ICPC
Feeling anxious/nervous/tense
2.2
8.5
89
441
SPAT1172
SPAT
Guidance concerning hydration
8.0
8.4
18
23
N05CF01
ATC
zopiclone; oral
1.8
8.4
165
1036
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
+∞
8.3
8
*
R52.2
ICD-10 Finland
Other chronic pain
4.5
8.3
28
64
E21.0
ICD-10 Finland
Primary hyperparathyroidism
7.2
8.3
19
27
L04AX01
ATC
azathioprine; systemic
3.5
8.3
38
115
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
8.2
42
138
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.9
8.1
14
12
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
8.1
82
400
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
8.1
102
545
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
8.0
246
1763
A28
ICPC
Limited function/disability NOS
2.3
8.0
74
342
E83.50
ICD-10 Finland
Hypercalcemia
7.4
8.0
18
25
WZA90
NOMESCO Finland
Other doctors statement
1.8
8.0
147
902
SPAT1240
SPAT
Therapeutic discussion
2.2
8.0
83
408
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
7.8
115
652
P76
ICPC
Depressive disorder
2.7
7.7
52
203
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
4.1
7.7
28
70
N05BA04
ATC
oxazepam; oral
1.8
7.6
135
816
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.4
7.6
36
112
XG466
NOMESCO Finland
Sleep oxymetry
5.9
7.6
20
35
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
7.6
99
537
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
7.6
64
285
EBA00
NOMESCO Finland
Extraction of tooth
1.7
7.5
189
1274
E87.6
ICD-10 Finland
Hypokalaemia
4.9
7.5
23
48
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.6
7.5
52
208
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.3
7.5
26
62
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.4
7.5
34
103
A12AA04
ATC
calcium carbonate; oral
6.6
7.5
18
28
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
13.6
7.4
12
9
A10AE04
ATC
insulin glargine; parenteral
2.7
7.4
50
195
C07AB07
ATC
bisoprolol; oral
1.7
7.4
206
1429
ZX114
NOMESCO Finland
Intramuscular
7.0
7.3
17
25
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
11.0
7.3
13
12
26520
ICD-8 Finland
Vitamin D deficiency, Osteomalacia
+∞
7.3
7
*
M83.9
ICD-10 Finland
Adult osteomalacia, unspecified
+∞
7.3
7
*
E83.3
ICD-10 Finland
Disorders of phosphorus metabolism and phosphatases
+∞
7.3
7
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
5.9
7.3
19
33
A02BC03
ATC
lansoprazole; oral
1.8
7.2
147
929
C08CA01
ATC
amlodipine; oral
1.8
7.2
151
963
N02AA05
ATC
oxycodone; systemic
2.2
7.2
73
354
T90
ICPC
Diabetes non-insulin dependent
2.0
7.1
92
496
N05AX08
ATC
risperidone; systemic
2.6
7.1
50
202
SPAT1252
SPAT
Overall medication plan or its review
3.0
7.1
40
140
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
7.1
135
837
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.0
7.0
21
43
G44.2
ICD-10 Finland
Tension-type headache
2.1
7.0
83
431
L17
ICPC
Foot/toe symptom/complaint
1.8
7.0
140
878
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
7.0
303
2352
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.3
6.9
33
104
M79.1
ICD-10 Finland
Myalgia
2.1
6.9
82
426
L16
ICPC
Ankle symptom/complaint
2.3
6.9
62
286
SPAT1262
SPAT
Handing over of treatment supplies
2.0
6.8
84
445
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
11.1
6.8
12
11
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
4.8
6.8
21
45
N06AX03
ATC
mianserin; oral
3.4
6.8
31
95
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
7.3
6.7
15
21
N06AB03
ATC
fluoxetine; oral
2.1
6.7
75
382
R5599
NOMESCO Finland
Other rehabilitation service
4.3
6.7
23
55
B81
ICPC
Anaemia vit B12/folate deficiency
4.3
6.7
23
55
TAB00
NOMESCO Finland
Lumbar puncture
3.3
6.6
32
102
SPAT1255
SPAT
Intravenous administration of medicine
2.9
6.6
39
142
F32
ICD-10 Finland
Depressive episode
2.9
6.6
39
142
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
6.6
152
994
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
6.6
95
531
L03
ICPC
Low back symptom/complaint
1.8
6.6
128
794
S18
ICPC
Laceration/cut
1.6
6.6
211
1511
P03
ICPC
Feeling depressed
2.1
6.6
72
364
R06.0
ICD-10 Finland
Dyspnoea
1.8
6.5
126
781
SPAT1312
SPAT
General health counselling
1.6
6.5
199
1407
P06
ICPC
Sleep disturbance
2.2
6.5
62
294
N05AH03
ATC
olanzapine; systemic
2.6
6.5
45
180
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.7
6.5
26
72
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
6.4
69
345
N07BB01
ATC
disulfiram; oral
3.4
6.4
29
88
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
70.6
6.4
7
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
5.0
6.4
19
39
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.5
6.4
21
48
R60.0
ICD-10 Finland
Localized oedema
2.2
6.4
61
288
UJF92
NOMESCO Finland
Capsular endoscopy
5.3
6.4
18
35
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
6.3
61
290
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
6.3
61
291
E66
ICD-10 Finland
Obesity
4.4
6.3
21
49
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
2.1
6.3
67
332
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
6.3
176
1212
N05AA02
ATC
levomepromazine; systemic
3.3
6.3
29
90
RD160
NOMESCO Finland
NA
+∞
6.3
6
*
BBA20
NOMESCO Finland
Exploration of parathyroid gland
27.0
6.2
8
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
5.1
6.2
18
36
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.4
6.2
17
32
B01AB05
ATC
enoxaparin; parenteral
1.7
6.2
145
953
N01
ICPC
Headache
2.0
6.2
81
440
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.1
6.1
22
55
J01FF01
ATC
clindamycin; systemic
1.7
6.1
137
886
T91
ICPC
Vitamin/nutritional deficiency
12.7
6.1
10
8
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.2
6.1
62
304
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.8
6.0
36
133
SPAT1283
SPAT
Restricted health certificate
1.7
6.0
125
792
A41.9
ICD-10 Finland
Sepsis, unspecified
4.0
6.0
22
56
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
6.0
46
195
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.3
6.0
54
248
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
518
2085
7.75
125.19
4.6
2.2
61.9
75.7
nmol/l
21.44
484
1897
188
333
7.48
108.09
5.0
3.8
85.8
74.1
ng/l
1.37
159
298
498
2280
5.74
93.00
11.0
6.4
1.2
1.2
mmol/l
0.49
434
1926
223
564
5.45
86.66
7.8
5.5
1.0
1.1
mmol/l
0.73
207
517
447
2072
4.54
76.69
9.3
5.8
1.2
1.2
mmol/l
0.70
420
1888
393
1936
3.52
55.42
6.7
4.4
35.0
36.4
g/l
4.79
368
1808
200
669
3.85
51.11
6.0
3.7
0.8
0.8
mmol/l
1.63
182
634
569
3845
4.35
43.32
11.3
6.7
86.1
76.4
u/l
3.17
553
3606
318
1593
2.91
39.72
3.2
3.1
2.3
2.4
mmol/l
0.69
284
1409
342
1796
2.86
38.84
2.4
1.8
90.6
96.9
pmol/l
1.72
219
917
258
1186
2.92
37.35
2.8
2.1
3.4
2.9
mg/l
1.93
228
1018
139
454
3.61
35.71
2.6
2.0
356.2
381.3
nmol/l
0.76
129
421
179
694
3.16
34.79
3.4
2.1
12.6
14.0
umol/l
1.48
173
636
412
2472
2.76
34.76
8.5
5.8
11.0
10.9
umol/l
0.09
385
2337
278
1379
2.75
34.20
3.0
2.1
189.8
227.3
u/l
0.25
265
1302
468
3021
2.86
33.77
12.6
8.7
4.2
4.0
e9/l
1.05
421
2641
161
631
3.05
30.31
3.5
2.1
2.3
2.4
g/l
0.28
153
585
122
409
3.43
29.77
3.1
2.9
10.4
10.3
g/l
0.13
109
371
219
1034
2.67
28.84
2.0
1.4
16.3
20.7
nmol/l
4.96
197
884
282
1508
2.51
28.58
4.2
2.4
61.0
57.2
u/l
0.55
264
1400
433
2836
2.51
27.79
7.8
4.4
6.9
6.5
mmol/l
1.94
406
2597
149
587
2.98
27.57
3.6
2.2
22.0
23.6
%
0.55
137
504
305
1738
2.40
26.32
5.2
3.1
—
—
—
0
0
102
329
3.48
26.29
1.7
2.5
66.0
67.4
g/l
0.90
92
301
230
1171
2.48
25.33
3.1
2.6
2559.7
7115.0
umol/l
1.04
200
1035
525
3848
2.74
25.26
6.1
3.8
13.5
10.3
mm/h
5.57
495
3554
173
773
2.67
25.00
2.3
1.6
1309.4
1209.7
nmol/l
0.41
135
573
104
354
3.30
24.54
11.2
6.9
9.0
8.4
mmol/l
0.39
99
336
226
1160
2.44
24.28
6.2
3.6
1.0
1.0
kg/l
0.03
25
156
74
212
3.80
22.67
1.3
1.3
2.3
2.4
u/ml
0.02
11
12
109
403
3.04
22.28
7.5
3.5
1.6
1.7
mmol/l
0.09
86
317
253
1410
2.28
22.10
6.2
3.7
0.0
0.0
estimate
0.80
69
512
66
181
3.94
21.49
2.2
2.3
—
—
—
0
0
106
394
3.01
21.43
9.8
6.8
1.7
1.4
mmol/l
1.33
96
382
174
843
2.44
20.80
2.9
2.7
2.4
2.4
mmol/l
0.12
153
744
106
402
2.95
20.64
3.6
2.3
0.2
0.2
g/l
3.17
100
374
385
2591
2.16
20.43
5.6
3.4
0.0
0.0
estimate
0.00
65
512
538
4170
2.53
19.90
6.0
3.9
14.8
14.6
pmol/l
0.84
505
3823
151
700
2.50
19.76
2.2
1.8
—
—
—
0
0
110
436
2.83
19.71
7.5
8.8
12.1
12.7
kpa
0.54
104
416
110
436
2.83
19.71
7.5
8.8
5.0
5.0
kpa
0.18
104
414
384
2605
2.12
19.66
7.2
4.6
0.0
0.0
estimate
0.50
73
516
387
2635
2.12
19.60
5.8
3.4
0.0
0.0
estimate
0.50
68
507
22
22
10.31
19.47
1.8
2.2
70.5
83.1
ug/l
0.17
22
22
243
1391
2.18
19.35
1.4
1.3
0.9
1.9
u/ml
1.28
70
381
85
300
3.10
18.71
2.0
1.7
—
—
—
0
0
112
460
2.73
18.70
2.7
4.8
227.6
240.3
u/l
0.80
107
436
236
1356
2.15
18.44
4.4
3.1
7.8
7.9
mmol/l
0.05
206
1144
107
435
2.74
18.20
7.7
8.9
1.8
0.9
mmol/l
1.04
77
344
180
944
2.24
17.56
1.8
1.6
84415991.4
17884573.3
pmol/l
0.36
154
794
363
2476
2.03
17.55
4.3
2.6
120.4
94.9
ug/l
1.38
338
2307
148
715
2.38
17.50
2.2
1.6
1.7
1.4
%
3.01
130
651
124
555
2.52
17.32
9.4
6.1
—
—
—
0
0
267
1646
2.04
16.99
4.9
2.9
30.6
30.9
u/l
0.07
259
1579
622
5323
3.66
16.63
26.5
12.8
139.4
139.7
mmol/l
1.52
609
5167
37
79
4.90
16.54
8.0
2.9
36.0
31.1
umol/l
0.63
32
66
589
4919
2.75
15.97
6.9
4.6
1.9
2.1
mu/l
0.41
556
4560
199
1123
2.10
15.91
3.6
3.0
2487.9
1026.5
ng/l
1.56
166
928
621
5339
3.52
15.85
26.9
12.8
3.9
3.9
mmol/l
0.67
608
5165
85
329
2.82
15.80
3.3
3.3
4.4
4.6
pmol/l
0.66
68
296
140
690
2.30
15.67
2.7
2.1
30.1
29.4
s
0.83
132
668
308
2040
1.95
15.60
5.9
3.5
—
—
—
0
0
200
1145
2.07
15.29
2.3
1.8
1.2
1.0
mg/l
0.34
153
841
182
1006
2.11
15.28
3.3
2.5
8.7
7.2
e6/l
0.52
169
882
89
359
2.71
15.27
5.8
3.4
1.2
1.2
mmol/l
1.02
84
315
110
493
2.48
15.21
2.0
1.8
—
—
—
0
0
29
55
5.47
14.78
1.4
1.2
—
—
—
0
0
270
1737
1.93
14.68
5.0
3.2
61.4
31.4
ng/l
0.54
192
1067
73
273
2.88
14.43
5.6
3.6
1.1
1.4
mmol/l
0.23
58
198
220
1335
1.97
14.10
4.2
3.0
0.5
0.3
e6/l
0.65
182
974
621
5415
3.27
13.91
24.2
11.6
19.9
21.9
mg/l
1.09
535
4144
234
1469
1.92
13.44
4.9
3.0
98.7
100.0
e6/l
0.01
199
1097
106
496
2.35
13.24
28.2
20.0
1.5
1.2
inr
0.59
14
70
86
367
2.54
13.12
8.9
9.8
123.8
121.3
g/l
0.44
80
351
89
388
2.49
12.98
4.3
2.3
58.0
71.1
ml/min/173m2
1.43
44
149
56
194
3.06
12.66
8.3
2.5
0.7
0.6
%
0.63
56
189
40
112
3.74
12.61
1.8
3.6
26.3
26.7
mg/l
0.04
28
84
40
112
3.74
12.61
1.8
3.6
32.0
114.5
mg/l
0.77
28
86
104
497
2.30
12.34
2.0
1.8
—
—
—
0
0
442
3443
1.85
12.23
6.7
4.2
33.0
1814.9
e6/l
—
9
44
39
110
3.70
12.17
1.8
3.6
1.2
2.3
ratio
—
5
12
70
280
2.68
12.16
2.0
1.4
—
—
—
0
0
548
4609
2.08
11.68
6.8
4.8
39.7
38.6
mmol/mol
1.43
514
4314
60
226
2.82
11.68
1.6
1.7
—
—
—
0
0
62
238
2.77
11.65
6.5
8.6
24.3
24.3
mmol/l
0.00
56
222
43
135
3.34
11.43
1.7
1.5
229.8
292.9
ug/g
0.89
24
75
80
352
2.45
11.41
2.6
2.4
5.9
7.3
ug/l
0.32
67
312
41
128
3.35
11.00
1.6
1.2
—
—
—
0
0
140
785
1.99
10.92
3.2
2.6
1.2
1.2
e6/l
0.09
94
427
50
179
2.94
10.68
1.5
1.6
0.0
0.1
iu/ml
0.60
13
28
192
1207
1.83
10.54
4.3
4.0
20.0
9.0
mg/mmol
1.27
138
750
631
5693
3.18
10.50
16.0
8.9
27.4
26.1
u/l
0.88
621
5498
20
38
5.40
10.17
1.5
1.1
69.9
64.5
u/l
0.14
15
27
18
32
5.75
9.79
4.6
2.6
79.8
95.9
%
1.23
18
32
42
144
3.05
9.68
4.3
7.9
1.6
1.5
%
0.17
36
130
453
3680
1.73
9.54
5.3
2.8
61.3
40.3
u/l
2.88
438
3477
154
932
1.85
9.43
1.3
1.3
45.4
30.9
iu/ml
0.20
42
301
128
749
1.88
8.66
4.6
2.8
4.3
2.9
e6/l
0.75
82
395
147
904
1.80
8.46
1.4
1.3
6.5
11.0
u/ml
0.36
62
364
560
4901
1.91
8.46
20.1
10.7
88.4
86.9
ml/min/173m2
0.65
483
3944
61
273
2.36
8.37
14.3
7.2
24.6
24.9
mmol/l
0.28
61
273
40
147
2.83
8.17
2.2
1.7
—
—
—
0
0
42
159
2.75
8.12
2.3
1.9
—
—
—
0
0
100
551
1.96
8.07
6.5
2.5
9.2
7.2
umol/l
0.32
82
466
44
172
2.67
8.01
1.9
2.5
1.5
1.5
g/l
0.01
39
152
33
110
3.10
7.99
4.8
2.8
25.3
24.1
mmol/l
0.63
33
96
316
2406
1.60
7.99
4.9
3.9
—
—
—
0
0
54
234
2.42
7.96
11.7
3.8
24.3
23.8
mmol/l
0.49
48
216
31
100
3.20
7.93
1.7
1.3
—
—
—
0
0
11
6
18.61
7.62
5.1
1.2
—
—
—
0
0
26
77
3.47
7.59
1.3
1.4
—
—
—
0
0
64
309
2.19
7.35
3.1
2.3
8431.8
4460.8
u/l
0.38
23
139
72
367
2.08
7.20
1.5
1.3
207.8
186.1
u/ml
0.10
65
339
26
80
3.34
7.17
4.2
2.3
15.9
16.0
%
0.04
18
40
136
863
1.72
6.92
4.4
3.6
100.2
468.7
ng/l
1.86
94
615
18
44
4.18
6.85
1.1
1.0
—
—
—
0
0
54
251
2.25
6.80
11.2
9.6
1.6
1.3
%
0.81
54
251
26
83
3.22
6.78
4.1
2.9
0.8
0.7
nmol/l
0.23
20
70
34
129
2.72
6.58
1.7
2.3
0.3
0.7
g/l
0.77
27
116
23
70
3.37
6.47
1.2
1.3
0.6
0.5
nmol/l
1.04
23
64
53
250
2.22
6.45
11.5
9.9
0.7
0.7
%
0.06
53
250
20
56
3.65
6.36
1.4
1.2
—
—
—
0
0
29
103
2.90
6.34
1.7
1.9
—
—
—
0
0
557
4996
1.71
6.08
4.9
3.9
6.0
5.8
mmol/l
2.32
515
4587
10
16
6.33
5.97
1.8
2.8
56.8
95.3
umol/l
—
5
11
35
143
2.53
5.88
1.3
2.1
3.0
3.0
g/l
0.07
23
114
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
29
109
2.74
5.73
3.8
2.8
0.3
0.3
u/ml
0.19
17
57
58
298
2.04
5.69
2.7
2.8
133.5
155.0
ng/l
0.28
51
271
36
152
2.45
5.65
1.3
2.1
6.9
7.2
g/l
0.57
23
119
36
152
2.45
5.65
1.3
2.1
4.0
3.6
g/l
0.95
23
113
36
152
2.45
5.65
1.3
2.1
—
—
—
0
0
34
141
2.49
5.55
1.8
2.1
10.2
11.5
mg/l
0.41
34
132
14
34
4.18
5.38
3.9
3.0
—
—
—
0
0
23
79
2.98
5.35
1.8
1.7
—
—
—
0
0
78
455
1.81
5.26
4.1
2.5
26.1
32.8
u/l
1.54
70
392
31
128
2.49
5.12
4.0
3.7
3.8
3.9
mmol/l
0.26
31
120
16
46
3.54
4.92
1.1
1.1
—
—
—
0
0
28
113
2.54
4.85
2.2
1.7
—
—
—
0
0
28
117
2.45
4.53
2.2
1.7
—
—
—
0
0
29
614
0.45
4.50
1.6
1.6
—
—
—
0
0
28
118
2.43
4.45
1.4
1.3
—
—
—
0
0
12
30
4.06
4.45
2.3
3.0
—
—
—
0
0
12
30
4.06
4.45
1.1
1.1
—
—
—
0
0
69
413
1.75
4.28
2.5
4.1
3.8
33.5
ug/l
0.92
54
345
16
51
3.19
4.23
1.8
1.7
31.8
32.8
pg
0.33
16
51
13
36
3.66
4.22
4.1
2.9
9.2
13.0
%
—
6
23
28
122
2.35
4.16
1.2
1.5
36.8
6.5
e6/l
0.74
17
99
28
122
2.35
4.16
1.2
1.5
78.5
194.0
e6/l
0.64
20
102
10
23
4.40
4.10
2.1
3.5
—
—
—
0
0
10
23
4.40
4.10
1.0
1.3
—
—
—
0
0
10
23
4.40
4.10
1.0
1.3
—
—
—
0
0
28
123
2.33
4.09
1.1
2.2
38.1
39.1
g/l
0.33
23
108
17
58
2.98
4.03
1.9
1.7
—
—
—
0
0
7
7
10.09
4.02
1.1
1.1
—
—
—
0
0
22
87
2.58
4.00
1.4
1.1
—
—
—
0
0
518
4700
1.46
3.99
28.4
14.2
13.9
13.5
%
6.65
512
4616
12
33
3.68
3.93
1.0
1.2
3505.2
32950.6
e6/l
—
6
18
17
59
2.93
3.92
1.0
1.1
—
—
—
0
0
568
5260
1.55
3.87
5.0
4.2
2.7
2.8
mmol/l
1.87
528
4881
21
84
2.55
3.75
2.4
1.7
—
—
—
0
0
560
5180
1.52
3.73
4.7
3.9
4.5
4.7
mmol/l
3.79
520
4838
18
67
2.73
3.68
1.1
1.1
—
—
—
0
0
70
444
1.64
3.54
1.3
1.2
420.3
157.8
iu/ml
0.60
23
182
23
99
2.37
3.54
2.0
2.5
116.9
108.1
ug/min
0.05
14
60
18
69
2.65
3.49
1.4
1.6
—
—
—
0
0
56
336
1.73
3.48
2.6
2.1
11.3
13.7
nmol/l
1.28
51
306
14
47
3.02
3.43
2.3
1.7
—
—
—
0
0
14
47
3.02
3.43
1.9
1.2
—
—
—
0
0
14
47
3.02
3.43
3.6
1.9
91.1
90.0
%
0.51
14
47
17
64
2.70
3.42
1.1
1.1
—
—
—
0
0
40
218
1.89
3.39
1.4
1.3
—
—
—
0
0
7
10
7.06
3.37
1.6
1.9
—
—
—
0
0
29
141
2.10
3.37
1.1
2.2
11.5
10.4
g/l
0.56
23
122
538
4967
1.44
3.33
4.3
3.5
1.4
1.2
mmol/l
5.26
501
4601
555
5161
1.46
3.24
4.6
3.8
1.4
1.5
mmol/l
8.12
516
4802
40
222
1.85
3.22
1.6
1.4
—
—
—
0
0
27
130
2.12
3.22
2.9
2.5
—
—
—
0
0
15
56
2.72
3.07
2.2
1.6
—
—
—
0
0
11
34
3.27
3.07
1.3
1.0
—
—
—
0
0
153
1177
1.39
3.06
3.2
2.1
—
—
—
0
0
44
256
1.77
3.06
1.4
1.5
297.4
304.8
mu/l
0.05
37
231
29
147
2.02
3.04
1.9
1.8
3.5
5.3
iu/l
0.58
13
56
50
304
1.70
2.99
1.7
1.4
18.7
24.4
iu/l
0.67
39
259
16
66
2.46
2.73
5.8
3.0
2.0
1.5
%
0.25
11
53
8
19
4.25
2.68
1.0
1.3
—
—
—
0
0
8
19
4.25
2.68
1.0
1.3
—
—
—
0
0
24
120
2.04
2.64
1.8
1.7
—
—
—
0
0
24
120
2.04
2.64
1.3
1.3
79.4
103.9
u/ml
—
5
28
8
20
4.04
2.57
1.1
1.3
—
—
—
0
0
12
44
2.76
2.56
1.8
1.6
—
—
—
0
0
12
44
2.76
2.56
1.8
1.6
—
—
—
0
0
12
44
2.76
2.56
1.8
1.6
—
—
—
0
0
6
11
5.49
2.55
1.0
1.3
—
—
—
0
0
21
104
2.05
2.38
4.0
3.3
3.7
4.2
e9/l
0.50
21
104
8
22
3.67
2.37
1.0
1.1
—
—
—
0
0
8
22
3.67
2.37
1.0
1.1
1300.4
1640.0
miu/ml
—
8
22
34
199
1.75
2.36
1.7
1.6
—
—
—
0
0
67
466
1.49
2.32
4.9
2.9
—
—
—
0
0
10
35
2.89
2.31
1.2
1.2
—
—
—
0
0
14
59
2.40
2.30
1.4
1.7
—
—
—
0
0
27
149
1.85
2.27
1.5
1.2
7.0
6.7
u/ml
—
8
24
21
107
1.99
2.22
5.7
3.6
54.6
57.6
%
0.76
21
107
38
234
1.66
2.22
2.5
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
36
2.80
2.21
1.0
1.1
—
—
—
0
0
7
19
3.71
2.15
1.1
1.4
10.0
8.5
ug/l
—
7
19
8
25
3.23
2.10
1.1
1.2
—
24.0
—
0
5
5
10
5.03
2.07
1.4
1.8
—
—
—
0
0
24
132
1.85
2.06
1.2
1.3
238.1
245.8
u/ml
0.06
17
82
5
11
4.57
1.94
2.8
1.5
611.0
10465.4
e6/l
—
5
5
11
45
2.47
1.94
1.5
1.1
—
—
—
0
0
158
1305
1.28
1.90
1.8
1.6
—
—
—
0
0
24
136
1.79
1.89
1.2
1.3
—
—
—
0
0
12
52
2.33
1.88
2.8
1.8
—
—
—
0
0
11
46
2.41
1.86
1.5
1.1
—
—
—
0
0
6
17
3.55
1.84
1.0
1.1
—
—
—
0
0
6
17
3.55
1.84
1.0
1.1
—
—
—
0
0
30
184
1.66
1.81
1.5
1.2
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
8
30
2.69
1.73
3.6
2.9
999.4
645.3
u/ml
—
8
30
14
68
2.08
1.71
2.5
1.7
—
—
—
0
0
22
126
1.77
1.70
1.5
1.2
49.3
25.7
u/ml
—
6
13
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
6
19
3.18
1.66
1.2
1.1
98.7
121.6
%
—
6
19
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
7
25
2.82
1.65
1.4
1.7
147.6
117.6
%
—
7
25
29
182
1.62
1.63
1.4
1.2
—
—
—
0
0
18
98
1.86
1.63
2.7
1.4
—
—
—
0
0
20
113
1.79
1.62
1.6
1.7
—
—
—
0
0
155
1301
1.25
1.62
1.7
1.6
1.6
1.4
mmol/l
1.70
138
1112
5
14
3.59
1.62
2.8
2.1
—
—
—
0
0
38
256
1.51
1.59
1.3
1.3
208.8
262.4
miu/ml
0.40
11
129
6
20
3.02
1.58
1.0
1.3
—
—
—
0
0
8
33
2.44
1.54
1.9
1.5
—
—
—
0
0
7
27
2.61
1.52
1.9
2.6
—
—
—
0
0
7
27
2.61
1.52
1.9
2.6
—
—
—
0
0
117
958
1.27
1.51
2.3
2.0
—
—
—
0
0
10
45
2.24
1.47
1.7
1.7
—
—
—
0
0
9
38
2.39
1.46
1.0
1.1
281.7
287.7
mg/l
—
9
33
5
17
2.96
1.36
3.2
2.0
0.2
0.1
nmol/l
—
5
12
5
17
2.96
1.36
1.0
1.2
—
—
—
0
0
16
266
0.59
1.27
1.6
1.5
—
—
—
0
0
16
92
1.76
1.26
1.4
1.3
—
—
—
0
0
16
92
1.76
1.26
1.4
1.3
—
—
—
0
0
6
25
2.41
1.24
1.0
1.0
—
—
—
0
0
32
452
0.69
1.22
1.3
1.5
—
—
—
0
0
10
49
2.06
1.22
1.5
2.1
107.1
105.7
mmol/l
—
10
49
10
49
2.06
1.22
4.4
4.3
—
—
—
0
0
5
19
2.64
1.22
1.2
1.1
—
—
—
0
0
11
58
1.91
1.12
1.6
1.2
—
—
—
0
0
8
40
2.01
1.12
1.5
1.5
15.9
18.0
ug/l
—
8
40
123
1053
1.21
1.07
2.3
2.2
—
—
—
0
0
9
48
1.89
1.00
1.0
1.0
—
—
—
0
0
9
50
1.81
0.97
1.3
1.1
—
—
—
0
0
13
77
1.70
0.95
1.0
1.1
—
—
—
0
0
7
37
1.90
0.94
2.9
1.4
0.8
1.0
g/l
—
7
37
50
628
0.78
0.93
2.7
2.8
0.6
0.7
ug/l
0.38
35
389
6
29
2.08
0.89
1.5
1.3
—
—
—
0
0
16
103
1.57
0.88
2.7
2.0
147.1
237.2
pmol/l
2.50
16
98
6
31
1.94
0.84
1.5
1.6
—
—
—
0
0
6
31
1.94
0.84
1.8
1.4
5.5
6.2
mmol/l
—
6
31
69
573
1.23
0.84
3.8
3.8
32.3
32.3
%
0.00
50
380
11
65
1.70
0.82
1.8
1.4
—
—
—
0
0
11
65
1.70
0.82
1.8
1.4
—
—
—
0
0
22
156
1.42
0.79
1.5
1.3
—
—
—
0
0
47
376
1.27
0.79
1.6
1.3
—
—
—
0
0
6
33
1.83
0.79
1.5
1.8
3.5
2.6
u/field
—
6
23
11
66
1.68
0.79
1.8
1.3
—
—
—
0
0
11
66
1.68
0.79
1.8
1.3
—
—
—
0
0
11
66
1.68
0.79
1.8
1.3
—
—
—
0
0
11
66
1.68
0.79
1.8
1.3
—
—
—
0
0
6
34
1.77
0.76
1.5
1.7
—
—
—
0
0
13
83
1.58
0.75
1.2
1.1
—
—
—
0
0
7
38
1.85
0.73
1.3
1.4
—
—
—
0
0
14
92
1.53
0.72
1.4
1.2
5.4
2.5
u/ml
—
5
33
14
92
1.53
0.72
1.4
1.3
6.5
6.6
u/ml
—
6
43
17
239
0.70
0.70
1.4
1.4
—
—
—
0
0
17
239
0.70
0.70
1.4
1.4
—
—
—
0
0
22
161
1.38
0.69
1.2
1.1
—
—
—
0
0
17
238
0.71
0.68
1.4
1.4
—
—
—
0
0
17
238
0.71
0.68
1.4
1.4
—
—
—
0
0
7
44
1.60
0.65
3.4
1.6
—
—
—
0
0
12
170
0.70
0.54
1.2
1.5
—
—
—
0
0
18
138
1.31
0.46
1.2
1.1
4.4
1.3
u/ml
0.33
12
55
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
26.7
—
0
17
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
8
113
0.70
0.37
1.4
1.2
—
—
—
0
0
18
224
0.80
0.37
1.4
1.6
—
—
—
0
0
6
43
1.40
0.35
1.2
1.1
—
—
—
0
0
15
189
0.79
0.34
2.1
1.6
—
—
—
0
0
24
286
0.83
0.34
1.4
1.4
—
—
—
0
0
68
616
1.12
0.34
2.5
1.9
—
—
—
0
0
113
1053
1.09
0.33
1.5
1.5
—
—
—
0
0
28
239
1.18
0.32
1.6
1.7
3.7
3.1
mg/l
0.19
19
162
7
99
0.70
0.31
1.0
1.1
—
2.2
—
0
47
5
40
1.25
0.22
1.6
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
2.6
—
0
6
0
12
0.00
0.21
0.0
1.0
—
0.0
—
0
7
0
13
0.00
0.21
0.0
1.0
—
0.0
—
0
8
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
524
5189
1.05
0.17
24.1
12.4
38.6
40.3
%
3.20
356
4074
12
101
1.19
0.16
1.3
1.1
—
—
—
0
0
22
196
1.13
0.16
1.3
1.5
—
—
—
0
0
37
341
1.09
0.16
1.1
1.0
—
—
—
0
0
89
851
1.05
0.15
3.4
3.9
22.0
21.1
%
0.22
38
375
10
118
0.85
0.14
1.9
1.5
—
—
—
0
0
11
128
0.86
0.13
1.3
1.3
—
—
—
0
0
404
4085
0.97
0.12
3.7
3.5
—
—
—
0
0
5
47
1.06
0.09
1.8
1.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
2.1
1.2
58.6
13.1
u/l
—
7
58
9
86
1.05
0.07
1.1
1.1
—
—
—
0
0
27
262
1.03
0.02
1.7
1.8
—
—
—
0
0
17
177
0.96
0.01
1.0
1.1
—
8.0
—
0
28
106
1056
1.00
0.00
3.7
4.3
1.5
2.4
ug/l
1.72
98
949
50
501
1.00
0.00
2.2
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
10.2
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_VIT_D_DEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_VIT_D_DEF | 1.849 [1.5, 2.29] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.396 |
During the follow-up period (1.1.1998 — 31.12.2019), 343 out of 2160 females with E4_VIT_D_DEF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_VIT_D_DEF | 2.763 [1.99, 3.84] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 271 out of 1341 males with E4_VIT_D_DEF died.
Mortality risk
Mortality risk for people of age
years, who have E4_VIT_D_DEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.172% | 0.546% |
| 5 | 1.005% | 3.188% |
| 10 | 2.601% | 7.561% |
| 15 | 5.141% | 14.755% |
| 20 | 9.109% | 24.402% |
Relationships between endpoints
↥Index endpoint: E4_VIT_D_DEF – Vitamin D deficiency
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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