Dislocation of lens

H7_LENSDISLOCATIO

lens disease: A disease involving the lens of camera-type eye. [database_cross_reference: MONDO:DesignPattern]

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H27.1
  • Hospital discharge: ICD-9 3793B
  • Hospital discharge: ICD-8 37870
  • Cause of death: ICD-10 H27.1
  • Cause of death: ICD-9 3793B
  • Cause of death: ICD-8 37870

2 out of 7 registries used, show all original rules.

607

4. Check minimum number of events

None

607

5. Include endpoints

None

607

6. Filter based on genotype QC (FinnGen only)

589

Control definitions (FinnGen only)

Control exclude
H7_LENS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
H27
Name in latin
Dislocatio lentis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5172 2808 2333
Only index persons 4530 2530 2000
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.07
Only index persons 0.09 0.09 0.08
Median age at first event (years)
Whole population 75.35 79.10 70.85
Only index persons 75.57 79.29 70.86

-FinnGen-

Key figures

All Female Male
Number of individuals 589 276 313
Unadjusted period prevalence (%) 0.12 0.10 0.14
Median age at first event (years) 74.86 77.19 72.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
606
Matched controls
6060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
WX140
NOMESCO Finland
Parabulbar anesthesy
101.7
307.7
295
56
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
261.9
307.7
430
56
H25.1
ICD-10 Finland
Senile nuclear cataract
100.6
307.7
340
76
H27.1
ICD-10 Finland
Dislocation of lens
+∞
307.7
570
*
S01ED51
ATC
timolol, combinations; ophthalmic
29.2
307.7
276
169
Z96.1
ICD-10 Finland
Presence of intraocular lens
221.3
307.7
465
89
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
21.5
297.5
481
921
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
132.1
265.4
134
13
WX100
NOMESCO Finland
Conjunctival surface anesthesia
64.1
247.0
139
28
S01BC05
ATC
ketorolac; ophthalmic
49.0
183.8
109
27
H26.4
ICD-10 Finland
After-cataract
487.6
182.0
173
5
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
52.1
178.2
104
24
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
36.7
177.3
114
38
H33.0
ICD-10 Finland
Retinal detachment with retinal break
39.9
169.5
106
32
CJB10
NOMESCO Finland
Laser discission of secondary cataract
240.7
161.7
160
9
XCW99
NOMESCO Finland
Other investigative procedure of eye
11.8
153.7
186
220
S01EC01
ATC
acetazolamide; systemic
37.7
146.9
93
29
H25.8
ICD-10 Finland
Other senile cataract
261.7
142.7
141
7
S01EE01
ATC
latanoprost; ophthalmic
12.8
141.8
156
160
S01EA05
ATC
brimonidine; ophthalmic
27.6
139.3
98
42
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
433.1
138.8
134
*
114
Kela drug reimbursment
Glaucoma
10.0
134.5
185
256
S01ED01
ATC
timolol; ophthalmic
17.2
127.0
112
79
XCH00
NOMESCO Finland
Eye pressure measurement
23.5
125.4
94
47
CKD60
NOMESCO Finland
Anterior vitrectomy
1339.1
116.7
110
*
S01EA03
ATC
apraclonidine; ophthalmic
67.7
110.7
61
10
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
637.1
110.6
106
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
13.2
106.1
109
99
CKD40
NOMESCO Finland
Endophotocoagulation of retina
52.1
105.3
61
13
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
397.5
101.3
99
*
S01EC04
ATC
brinzolamide; ophthalmic
15.1
100.4
94
73
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
9.1
94.9
131
178
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
46.3
85.8
51
12
XCK00
NOMESCO Finland
Perimetry
9.9
81.8
102
121
XCK10
NOMESCO Finland
Photography of fundus of eye
7.2
78.5
135
233
H25.0
ICD-10 Finland
Senile incipient cataract
16.6
77.0
67
45
S01EC54
ATC
brinzolamide, combinations; ophthalmic
37.1
76.3
48
14
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
34.7
74.8
48
15
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
+∞
74.5
70
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.6
74.1
374
1583
H40.0
ICD-10 Finland
Glaucoma suspect
7.8
72.8
113
174
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
11.1
72.0
81
83
ZXA00
NOMESCO Finland
Right side
4.5
70.4
264
892
H43.1
ICD-10 Finland
Vitreous haemorrhage
18.8
67.8
55
32
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
373.6
66.9
66
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
14.2
66.6
63
49
ZXA05
NOMESCO Finland
Left side
4.4
65.3
236
769
S01EE05
ATC
tafluprost; ophthalmic
10.6
62.5
72
76
S01BC03
ATC
diclofenac; ophthalmic
16.4
54.2
47
31
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.5
53.3
164
466
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
13.2
51.9
51
42
S01EC03
ATC
dorzolamide; ophthalmic
19.0
51.1
41
23
WX002
NOMESCO Finland
Sedation and analgesia
4.0
50.2
184
592
CJF20
NOMESCO Finland
Removal of artificial lens
+∞
47.5
45
*
H27.0
ICD-10 Finland
Aphakia
+∞
46.5
44
*
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
248.4
45.6
46
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
44.3
42
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
81.0
40.5
45
6
ZXA10
NOMESCO Finland
Bilateral
4.1
39.6
129
376
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
7.4
38.9
59
87
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
67.6
38.7
44
7
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
36.8
35
*
S01AX11
ATC
[U] ofloxacin
7.6
36.2
53
75
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
+∞
35.8
34
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
6.3
35.6
63
109
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
191.0
35.1
36
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
9.5
34.6
42
47
H26.2
ICD-10 Finland
Complicated cataract
356.2
34.3
34
*
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
340.7
32.2
32
*
WX199
NOMESCO Finland
Other local analgesia
10.6
32.1
36
36
H26.02
ICD-10 Finland
Presenil cataract
119.9
32.0
34
*
S01EX03, ,
ATC
8.7
31.6
41
50
TCG10
NOMESCO Finland
Removal of sutures from cornea
+∞
31.5
30
*
S01BA04
ATC
prednisolone; ophthalmic
9.4
31.0
38
43
CS494
NOMESCO Finland
Other visual field testing
10.0
30.9
36
38
H40.9
ICD-10 Finland
Glaucoma, unspecified
10.8
30.0
33
32
ZXD20
NOMESCO Finland
Day surgery
3.9
29.6
97
281
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
+∞
29.4
28
*
Q87.4
ICD-10 Finland
Marfan syndrome
+∞
29.4
28
*
S01EE03
ATC
bimatoprost; ophthalmic
8.6
28.9
38
47
S01BA01
ATC
dexamethasone; ophthalmic
7.2
28.8
44
65
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
7.6
28.7
42
59
S01EE04
ATC
travoprost; ophthalmic
8.6
26.7
35
43
3793B
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[DISLOCATIO LENTIS]
+∞
26.2
25
*
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
271.6
25.9
26
*
CHC05
NOMESCO Finland
Iridotomy
24.7
25.1
35
15
H35.36
ICD-10 Finland
Macular cyst
50.6
24.5
29
6
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
6.4
24.0
41
68
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
70.4
24.0
27
*
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.7
23.7
28
30
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
+∞
23.1
22
*
3661A
ICD-9 Finland
Cataract, Senile cataract
+∞
23.1
22
*
37870
ICD-8 Finland
Other diseases of eye, Subluxatio et luxatio lentis
+∞
23.1
22
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
86.9
22.8
25
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
4.8
22.4
53
119
ZXE00
NOMESCO Finland
One hour or less
2.3
21.3
244
1367
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
21.0
20
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
114.0
20.7
22
*
A98
ICPC
Health maint/preventive medicine
3.2
20.4
535
4249
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
206.5
19.7
20
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
19.6
243
1397
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
27.1
19.3
26
10
J01DB01
ATC
cefalexin; oral
2.5
19.1
471
3552
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
18.9
173
873
CJD30
NOMESCO Finland
Pars plana lensectomy
+∞
18.8
18
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
18.8
18
*
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
+∞
18.8
18
*
H21.0
ICD-10 Finland
Hyphaema
72.2
18.8
21
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
39.8
18.7
23
6
WX110
NOMESCO Finland
Infiltration anesthesia
2.2
18.6
363
2477
H53.9
ICD-10 Finland
Visual disturbance, unspecified
5.6
18.0
35
66
H33.3
ICD-10 Finland
Retinal breaks without detachment
5.4
17.9
36
70
N02BE01
ATC
paracetamol; systemic, rectal
2.8
17.8
524
4205
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
+∞
17.8
17
*
3660C
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA PRAESENILIS]
+∞
17.8
17
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
16.9
77
273
CG2T4
NOMESCO Finland
Topography assessment of cornea
23.8
16.5
23
10
H04.10
ICD-10 Finland
Dry eye syndrome
3.3
16.5
65
211
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
16.2
15.8
25
16
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
34.4
15.8
20
6
CJW99
NOMESCO Finland
Other operation on lens
+∞
15.7
15
*
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
15.7
15
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
39.2
15.5
19
5
CKC12
NOMESCO Finland
Photocoagulation of retina
5.3
15.2
31
61
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
14.9
241
1497
CJF99
NOMESCO Finland
Other operation on artificial lens
+∞
14.6
14
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
+∞
14.6
14
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
82.1
14.6
16
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
27.9
14.3
19
7
ZXD05
NOMESCO Finland
Urgent procedure
2.0
14.3
201
1184
S01EB01
ATC
pilocarpine; ophthalmic
19.7
14.3
21
11
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
14.2
116
551
S18
ICPC
Laceration/cut
1.9
14.1
270
1771
A02BC02
ATC
pantoprazole; systemic
2.0
13.6
393
2939
H18.1
ICD-10 Finland
Bullous keratopathy
+∞
13.6
13
*
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
+∞
13.6
13
*
CJG99
NOMESCO Finland
Other operation on dislocated lens
+∞
13.6
13
*
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
34.9
13.6
17
5
L28
ICPC
Limited function/disability (L)
2.2
13.6
143
754
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
143.1
13.5
14
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.3
13.5
52
166
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
13.5
60
209
H52.1
ICD-10 Finland
Myopia
10.4
13.1
25
25
S01ED02
ATC
betaxolol; ophthalmic
17.2
13.1
20
12
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
12.9
293
2014
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
12.9
242
1565
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
12.9
411
3152
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
+∞
12.5
12
*
CJF35
NOMESCO Finland
Correcting the position of the artificial lens and attaching it to the sclera
+∞
12.5
12
*
3639
FHL
Other measure in this category
+∞
12.5
12
*
S01FA01
ATC
atropine; ophthalmic
24.9
12.5
17
7
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
24.9
12.5
17
7
SPAT1153
SPAT
Removal of sutures
1.9
12.3
193
1172
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
18.5
12.1
18
10
SPAT1254
SPAT
Administration of medicine
2.2
12.0
114
574
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.7
12.0
70
283
AA1AD
NOMESCO Finland
CT of head and brain
1.9
11.7
190
1163
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
11.6
154
880
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
11.5
222
1437
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
122.2
11.5
12
*
CHD00
NOMESCO Finland
Laser trabeculoplasty
10.8
11.3
21
20
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
11.2
138
766
SPAT1325
SPAT
Vaccination
1.8
11.1
221
1442
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.6
10.9
36
104
XCD20
NOMESCO Finland
Photoangiography of eye
10.8
10.8
20
19
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.8
10.8
33
90
H27.8
ICD-10 Finland
Other specified disorders of lens
61.1
10.7
12
*
H02AB06
ATC
prednisolone; systemic
1.8
10.6
277
1950
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
10.5
170
1034
H26.1
ICD-10 Finland
Traumatic cataract
+∞
10.4
10
*
CJF40
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber
+∞
10.4
10
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
10.4
210
1369
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
10.3
79
362
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.0
10.1
132
747
C07AB07
ATC
bisoprolol; oral
1.7
10.0
337
2536
A04
ICPC
Weakness/tiredness general
2.1
10.0
100
513
SPAT1263
SPAT
Sampling
1.8
9.9
228
1542
H16.0
ICD-10 Finland
Corneal ulcer
4.0
9.8
28
73
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
13.7
9.7
16
12
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
10.3
9.6
18
18
B01AC04
ATC
clopidogrel; oral
2.0
9.4
125
709
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
101.6
9.4
10
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
9.4
9
*
3631
FHL
Setting up an artificial lens as the only procedure
+∞
9.4
9
*
CJG20
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in posterior chamber
+∞
9.4
9
*
J01CA04
ATC
amoxicillin; systemic
1.8
9.3
427
3474
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
7.5
9.3
21
29
H57.1
ICD-10 Finland
Ocular pain
4.4
9.2
23
54
Z3231
NOMESCO Finland
Registered nurse
1.8
9.1
170
1075
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.9
9.1
44
161
H25.9
ICD-10 Finland
Senile cataract, unspecified
15.9
9.1
14
9
H40.8
ICD-10 Finland
Other glaucoma
37.3
9.0
11
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.5
9.0
59
252
CKC10
NOMESCO Finland
Local photocoagulation of retina
7.0
8.9
21
31
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
8.9
157
977
A46
ICD-10 Finland
Erysipelas
2.0
8.7
106
583
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
50.7
8.7
10
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
50.7
8.7
10
*
K02.1
ICD-10 Finland
Caries of dentine
1.7
8.6
254
1823
CKC20
NOMESCO Finland
Cryopexy of undetached retina
28.0
8.5
11
*
C08CA01
ATC
amlodipine; oral
1.7
8.5
255
1835
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
8.5
107
596
3643
FHL
Vitrectomy through pars Plana
91.3
8.4
9
*
37520
ICD-8 Finland
Glaucoma, Secondary
91.3
8.4
9
*
E0000UV, ,
ATC
1.7
8.4
215
1482
TK800
NOMESCO Finland
Hemodialysis
4.8
8.4
19
41
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.2
8.4
33
107
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
8.3
8
*
3642
FHL
Anterior vitrectomy
+∞
8.3
8
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
8.3
8
*
37405
ICD-8 Finland
Cataract, Traumatica
+∞
8.3
8
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
8.3
168
1084
D07AC01
ATC
betamethasone; topical
1.7
8.3
193
1297
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.3
8.3
21
50
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
8.2
145
898
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
8.2
193
1298
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
8.2
239
1704
S01BA07
ATC
fluorometholone; ophthalmic
8.3
8.1
17
21
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.0
176
1161
T89
ICPC
Diabetes insulin dependent
4.0
7.9
22
56
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
7.9
74
368
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
7.9
54
235
SPAT1234
SPAT
Support of social functional capacity
2.6
7.9
47
192
D07AC13
ATC
mometasone; topical
1.8
7.8
153
976
R53
ICD-10 Finland
Malaise and fatigue
1.8
7.8
145
913
R06AE07
ATC
cetirizine; oral
1.7
7.7
204
1412
H3603, E103,
ICD-10 Finland
45.6
7.7
9
*
DAX08
NOMESCO Finland
Fitting of hearing aid
2.7
7.7
41
158
B01AB05
ATC
enoxaparin; parenteral
1.7
7.7
186
1258
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
7.7
192
1310
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
25.4
7.6
10
*
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
9.0
7.6
15
17
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
7.5
109
636
CFB00
NOMESCO Finland
Suture of conjunctiva
81.1
7.4
8
*
CFW99
NOMESCO Finland
Other operation on conjunctiva
81.1
7.4
8
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
81.1
7.4
8
*
Z01.9
ICD-10 Finland
Special examination, unspecified
2.8
7.4
36
132
SPAT1312
SPAT
General health counselling
1.7
7.3
159
1042
J01MA12
ATC
levofloxacin; systemic
1.8
7.3
122
741
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.9
7.3
21
55
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
7.3
7
*
CJC15
NOMESCO Finland
Intracapsular cataract extraction with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
7.3
7
*
H26.3
ICD-10 Finland
Drug-induced cataract
+∞
7.3
7
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
7.3
7
*
WZC30
NOMESCO Finland
Teaching
1.9
7.3
92
511
C03CA01
ATC
furosemide; systemic
1.6
7.3
256
1897
N02BF01
ATC
gabapentin; oral
2.7
7.3
39
151
H33.5
ICD-10 Finland
Other retinal detachments
16.0
7.2
11
7
XCW10
NOMESCO Finland
Assessment of vision
16.0
7.2
11
7
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.0
7.2
87
475
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
3.4
7.2
26
80
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
7.1
79
419
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
7.1
117
707
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.1
237
1731
R06.0
ICD-10 Finland
Dyspnoea
1.7
7.1
157
1033
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
7.1
213
1517
N03AX16
ATC
[U] pregabalin
1.8
7.1
123
756
DFF00
NOMESCO Finland
Pure tone audiometry
2.1
7.0
66
329
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
7.0
61
295
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.0
311
2430
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
6.9
47
204
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
14.0
6.9
11
8
SPAT1172
SPAT
Guidance concerning hydration
3.5
6.9
23
67
W22
ICD-10 Finland
Striking against or struck by other object(s)
2.8
6.8
33
121
H54.4
ICD-10 Finland
Blindness, monocular
40.5
6.8
8
*
37403
ICD-8 Finland
Cataract, Complicata
40.5
6.8
8
*
H20.8
ICD-10 Finland
Other iridocyclitis
40.5
6.8
8
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.5
6.8
23
68
Z31.5
ICD-10 Finland
Genetic counselling
3.4
6.8
24
73
C01DA14
ATC
isosorbide mononitrate; oral
1.7
6.7
141
914
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.7
234
1724
R03BA05
ATC
fluticasone; inhalant
1.9
6.7
90
511
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.7
6.7
36
140
R01AD08
ATC
fluticasone; nasal
1.7
6.6
126
794
H02AB04
ATC
methylprednisolone; systemic
1.9
6.6
81
445
EB1VA, ,
NOMESCO Finland
2.4
6.6
47
209
SPAT1043
SPAT
Audiometry
2.0
6.6
69
359
C10AA07
ATC
rosuvastatin; oral
1.7
6.6
155
1036
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
6.6
139
903
SFA10
NOMESCO Finland
One-surface restoration
1.6
6.5
231
1704
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.4
6.5
18
34
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
6.5
35
136
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.5
221
1617
Q12.0
ICD-10 Finland
Congenital cataract
70.6
6.4
7
*
H3601, E103,
ICD-10 Finland
70.6
6.4
7
*
R60.0
ICD-10 Finland
Localized oedema
1.9
6.4
78
428
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.4
140
917
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
6.3
120
756
UKC02
NOMESCO Finland
Cystoscopy
1.8
6.3
111
684
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.3
91
528
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
18.2
6.3
9
5
3628
FHL
Intracapsular cataract surgery and implantation of an artificial lens
+∞
6.3
6
*
3662A
ICD-9 Finland
Cataract, Traumatic cataract
+∞
6.3
6
*
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
6.3
6
*
37401
ICD-8 Finland
Cataract, Praesenilis
+∞
6.3
6
*
S01XA18
ATC
ciclosporin; ophthalmic
27.0
6.2
8
*
L08
ICPC
Shoulder symptom/complaint
1.8
6.2
104
631
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.7
6.2
118
744
H16.9
ICD-10 Finland
Keratitis, unspecified
7.8
6.1
13
17
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.4
6.1
41
177
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.9
6.1
29
105
CHD35
NOMESCO Finland
Laser goniopuncture
12.7
6.1
10
8
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.1
102
619
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.5
6.1
20
58
-44
ICPC
Preventive immunization/medic
2.1
6.0
56
278

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
240
1260
2.50
25.17
4.7
4.4
—
—
—
0
0
541
4196
3.70
24.25
25.5
19.2
139.29
139.50
mmol/l
0.94
523
4055
541
4205
3.67
23.97
26.0
19.4
4.02
4.00
mmol/l
0.55
522
4057
534
4158
3.39
22.73
12.8
10.4
25.24
24.91
u/l
0.10
505
3956
448
3200
2.53
22.46
8.4
7.2
82.90
81.70
u/l
0.17
413
2951
547
4350
3.64
21.85
31.9
23.4
239.46
241.39
e9/l
0.26
530
4185
547
4350
3.64
21.85
32.3
23.6
38.32
39.18
%
1.79
512
3989
547
4351
3.64
21.82
31.8
23.3
92.54
91.58
fl
4.19
536
4236
547
4352
3.64
21.79
31.9
23.4
6.90
6.92
e9/l
0.10
528
4166
547
4352
3.64
21.79
31.8
23.3
30.61
30.40
pg
1.76
536
4238
547
4352
3.64
21.79
31.9
23.4
4.27
4.40
e12/l
5.64
528
4169
547
4353
3.64
21.76
32.1
23.5
129.86
132.73
g/l
3.82
537
4237
261
1500
2.30
21.53
3.7
3.1
2663.42
1814.31
ng/l
1.04
230
1300
190
955
2.44
21.30
1.8
1.7
1051.14
1188.51
nmol/l
1.25
135
695
414
2914
2.33
20.49
5.0
3.8
16.62
14.74
mm/h
1.17
365
2642
511
3981
2.81
19.78
22.9
16.1
27.13
27.59
mg/l
0.11
437
3213
334
2175
2.19
19.73
23.4
17.7
1.43
1.39
inr
0.19
115
586
335
2207
2.16
18.93
8.3
6.5
1.21
1.21
mmol/l
1.17
274
1864
335
2215
2.15
18.65
5.5
6.0
11.47
12.60
umol/l
1.29
316
2088
261
1586
2.13
17.92
2.5
2.1
79.04
79.86
nmol/l
0.16
218
1367
279
1743
2.11
17.77
4.8
3.9
254.51
61.32
ng/l
0.41
232
1309
465
3556
2.32
17.16
5.5
4.6
2.15
2.04
mu/l
0.42
407
3160
511
4076
2.62
17.09
21.4
15.0
—
—
—
0
0
363
2528
2.09
16.98
5.6
4.7
6.85
6.79
mmol/l
0.23
340
2359
299
1958
2.04
16.36
7.0
5.3
1.69
1.86
e9/l
1.32
268
1691
288
1864
2.04
16.24
2.2
2.0
93.82
94.01
pmol/l
0.02
153
914
301
1982
2.03
16.15
6.9
5.4
0.21
0.19
e9/l
1.07
267
1696
294
1920
2.03
16.14
6.8
5.2
0.04
0.04
e9/l
0.28
258
1620
292
1914
2.01
15.75
6.8
5.2
0.63
0.61
e9/l
0.54
256
1610
466
3634
2.22
15.34
6.8
6.1
41.10
40.60
mmol/mol
0.48
410
3286
333
2300
1.99
15.32
9.2
8.5
4.39
4.33
e9/l
0.16
300
1972
483
3825
2.29
15.25
5.4
5.1
2.45
2.60
mmol/l
3.27
426
3411
277
1802
1.99
15.07
7.1
5.4
59.74
58.85
%
0.56
254
1680
272
1764
1.98
14.88
7.1
5.6
—
—
—
0
0
97
417
2.58
14.73
6.0
4.1
—
—
—
0
0
274
1792
1.97
14.53
7.1
5.3
2.91
2.77
%
0.40
253
1661
388
2859
1.99
14.45
4.4
3.7
15.51
15.20
pmol/l
1.64
338
2532
279
1845
1.95
14.24
7.4
5.5
24.96
25.91
%
0.72
259
1714
274
1802
1.95
14.21
7.5
5.6
8.69
8.90
%
0.43
253
1673
295
1993
1.94
14.08
7.7
5.8
1.21
1.21
mmol/l
0.68
263
1795
469
3730
2.14
13.72
4.9
4.5
4.29
4.48
mmol/l
3.45
409
3344
194
1144
2.02
13.68
2.6
2.1
3.11
3.15
mg/l
0.06
153
942
242
1545
1.94
13.54
3.3
3.2
2.34
2.36
mmol/l
1.70
194
1301
465
3695
2.11
13.50
5.0
4.4
1.42
1.44
mmol/l
0.34
406
3296
287
1940
1.91
13.50
5.1
4.5
34.03
34.45
g/l
0.59
262
1771
385
2869
1.94
13.39
5.5
4.5
—
—
—
0
0
180
1045
2.03
13.18
2.7
2.3
—
—
—
0
0
324
2290
1.89
13.17
3.7
3.0
72.01
52.19
u/l
1.64
290
2074
452
3576
2.04
12.98
4.5
4.0
1.30
1.26
mmol/l
0.49
390
3155
243
1584
1.89
12.54
3.5
2.7
173.10
164.50
ug/l
0.22
209
1416
282
1936
1.85
12.29
2.6
2.5
—
—
—
0
0
68
269
2.72
12.12
3.6
3.8
7.42
7.41
ph
0.13
13
25
89
402
2.42
12.08
2.2
2.4
67.16
66.86
e9/l
0.03
74
307
259
1750
1.84
11.73
7.2
5.4
0.65
0.63
%
0.25
236
1621
68
274
2.67
11.69
3.7
3.8
4.94
5.20
kpa
1.21
63
258
468
3815
2.00
11.43
5.4
4.7
6.17
6.08
mmol/l
0.57
400
3391
232
1532
1.83
11.19
2.4
2.2
—
—
—
0
0
379
2899
1.82
11.16
4.5
4.1
—
—
—
0
0
230
1517
1.83
11.12
3.6
3.2
—
—
—
0
0
213
1381
1.84
10.83
2.6
2.3
—
—
—
0
0
89
427
2.27
10.48
2.6
2.4
6.65
6.70
ug/l
0.01
73
360
210
1368
1.82
10.44
4.7
4.2
—
—
—
0
0
105
543
2.13
10.26
2.5
2.3
1.86
1.78
%
0.32
90
487
175
1083
1.87
10.23
1.8
1.6
19.50
19.71
nmol/l
0.06
141
915
196
1271
1.80
9.78
2.5
2.4
57.23
123.03
u/l
0.52
180
1169
126
714
1.97
9.55
3.3
3.0
0.82
0.81
mmol/l
0.41
117
660
198
1298
1.78
9.47
2.3
2.0
186.77
281.08
u/l
0.80
189
1203
46
169
2.86
9.41
4.0
4.6
24.43
25.33
mmol/l
1.15
41
155
108
602
1.97
8.52
2.0
1.9
—
—
—
0
0
161
1021
1.79
8.48
3.0
2.8
376.94
12238.85
umol/l
6.35
124
866
28
83
3.49
8.17
1.2
1.3
64.00
62.36
mmol/l
0.08
20
70
120
716
1.84
7.66
3.5
2.3
11.34
12.23
umol/l
0.76
106
660
150
959
1.75
7.59
1.7
1.7
465.08
425.91
pmol/l
1.02
123
773
111
657
1.84
7.25
3.6
2.3
2.20
2.26
g/l
0.50
98
603
72
368
2.09
7.19
5.8
3.3
1.23
1.22
mmol/l
0.16
65
312
52
235
2.33
7.02
3.9
3.3
4.23
6.00
e9/l
0.69
33
166
148
962
1.71
7.00
3.2
2.6
4.59
5.37
e6/l
0.55
137
862
190
1323
1.64
6.90
5.7
3.9
7.39
7.40
ph
0.50
55
230
104
615
1.83
6.79
3.7
2.4
20.76
22.49
%
0.74
89
520
49
220
2.34
6.71
1.7
1.7
1.45
1.64
g/l
0.69
40
192
179
1240
1.63
6.59
3.6
3.1
876.01
265.72
mg/l
0.53
109
799
182
1270
1.62
6.49
3.5
3.0
6.41
7.10
mmol/l
1.89
145
1037
260
1974
1.56
6.45
4.3
3.8
0.00
0.00
estimate
-0.00
59
360
102
609
1.81
6.44
8.6
4.9
1.02
1.02
mmol/l
0.10
94
551
19
51
3.81
6.41
1.3
1.1
—
—
—
0
0
46
206
2.33
6.35
3.8
4.0
—
—
—
0
0
256
1952
1.54
6.15
5.5
5.2
0.00
0.00
estimate
-0.00
60
365
36
148
2.52
5.98
1.3
1.3
—
—
—
0
0
396
3330
1.55
5.96
24.4
19.4
16.09
15.08
%
2.16
388
3257
72
394
1.94
5.95
2.5
2.1
0.19
0.20
g/l
0.38
66
362
18
51
3.61
5.64
2.9
3.1
—
—
—
0
0
254
1960
1.51
5.64
4.4
3.8
0.00
0.00
estimate
0.50
68
402
35
147
2.47
5.57
3.0
3.7
47.09
98.22
mg/l
0.64
28
122
35
147
2.47
5.57
3.0
3.7
35.46
37.21
mg/l
0.10
28
123
185
1338
1.55
5.53
4.3
3.6
13.74
10.38
mg/mmol
0.30
107
833
20
62
3.30
5.49
4.8
2.5
—
—
—
0
0
210
1565
1.52
5.46
4.6
3.8
101.77
143.11
e6/l
0.37
166
1122
172
1229
1.56
5.41
4.0
3.4
—
—
—
0
0
141
963
1.60
5.37
3.4
3.0
2.47
2.47
mmol/l
0.05
122
823
59
322
1.92
4.93
5.4
3.9
—
—
—
0
0
139
965
1.57
4.91
3.1
2.9
497.43
556.53
mosm/kgh2o
3.02
118
824
112
739
1.63
4.88
1.6
1.9
29.20
29.99
s
0.91
105
713
58
318
1.91
4.78
2.7
2.4
—
—
—
0
0
186
1383
1.50
4.78
4.2
3.4
53.31
80.35
e6/l
0.58
156
1066
52
275
1.97
4.76
3.0
3.5
0.47
0.63
%
0.32
17
98
150
1068
1.54
4.72
4.8
4.1
0.00
0.00
estimate
-0.00
58
340
59
327
1.89
4.71
1.8
1.9
400.75
373.11
nmol/l
0.38
48
289
21
74
2.90
4.70
3.5
2.4
15.27
15.90
%
0.38
14
36
69
403
1.80
4.67
1.2
1.3
—
—
—
0
0
173
1276
1.50
4.60
4.1
3.4
0.35
0.58
e6/l
1.48
144
978
72
431
1.76
4.49
2.3
1.6
—
—
—
0
0
15
44
3.47
4.49
2.1
2.0
90.47
89.38
%
0.40
15
44
11
19
5.87
4.46
1.0
1.1
—
—
—
0
0
78
479
1.72
4.45
2.2
2.9
219.75
266.53
ng/l
0.52
70
439
224
1748
1.45
4.44
15.4
9.4
0.00
0.00
e9/l
0.66
193
1418
82
514
1.69
4.34
1.3
1.2
—
—
—
0
0
53
292
1.89
4.32
3.3
3.5
0.06
0.15
%
0.66
17
97
57
322
1.85
4.30
2.3
1.5
—
—
—
0
0
80
500
1.69
4.29
2.1
1.7
—
—
—
0
0
121
839
1.55
4.26
1.8
1.6
1.54
1.39
mg/l
0.14
94
653
94
620
1.61
4.09
1.6
1.4
2.53
2.70
g/l
0.37
56
340
139
1004
1.50
4.03
7.6
6.6
—
—
—
0
0
102
689
1.58
4.01
1.4
1.2
0.86
1.10
u/ml
0.60
29
156
212
1663
1.42
4.00
5.4
5.2
6.81
7.14
ug/l
0.02
187
1466
13
32
4.13
3.92
1.5
1.9
—
—
—
0
0
63
378
1.74
3.91
2.1
1.5
—
—
—
0
0
25
107
2.39
3.88
3.0
4.0
—
—
—
0
0
48
267
1.87
3.82
3.5
3.6
0.00
1.29
%
0.58
14
76
54
312
1.80
3.81
3.3
3.5
0.83
0.94
%
0.09
18
118
39
204
1.97
3.72
1.3
1.4
—
—
—
0
0
24
105
2.34
3.57
1.3
1.6
—
—
—
0
0
13
36
3.67
3.51
2.9
2.7
—
—
—
0
0
20
82
2.49
3.41
2.8
2.2
—
—
—
0
0
31
154
2.07
3.41
2.4
2.3
—
—
—
0
0
7
10
7.06
3.37
1.0
1.5
—
—
—
0
0
36
192
1.93
3.27
1.9
1.9
0.64
1.25
ug/l
0.72
28
164
134
1000
1.44
3.25
1.4
1.3
—
—
—
0
0
19
79
2.45
3.16
5.2
2.7
—
—
—
0
0
28
138
2.08
3.16
3.0
3.4
0.73
0.80
nmol/l
0.58
22
110
50
304
1.70
3.00
3.4
3.2
—
—
—
0
0
22
101
2.22
2.96
2.5
2.0
124.59
132.25
g/l
1.01
17
72
14
52
2.73
2.90
1.7
1.3
—
—
—
0
0
15
58
2.63
2.89
2.3
2.6
—
—
—
0
0
66
440
1.56
2.77
1.3
1.3
—
—
—
0
0
31
168
1.89
2.72
2.7
2.6
10.28
10.02
g/l
0.12
22
155
57
370
1.60
2.68
3.7
3.4
—
—
—
0
0
75
519
1.51
2.66
3.2
4.1
27.79
24.44
ug/l
0.05
60
443
61
404
1.57
2.64
2.7
2.6
66.21
65.63
g/l
0.27
53
376
15
61
2.50
2.64
1.6
1.3
—
—
—
0
0
28
149
1.92
2.60
2.5
2.2
523.89
887.36
ug/l
0.43
28
143
7
15
4.71
2.60
1.0
1.3
—
—
—
0
0
8
20
4.04
2.57
5.0
13.6
—
—
—
0
0
56
366
1.58
2.57
5.2
3.4
148.68
90.71
ng/l
1.97
44
315
12
42
2.89
2.56
1.4
2.4
2.40
2.17
u/field
—
5
12
35
202
1.78
2.54
3.1
3.3
—
—
—
0
0
21
102
2.10
2.50
4.3
2.5
2.04
1.65
mg/l
0.95
16
96
125
964
1.37
2.48
3.9
3.8
—
—
—
0
0
130
1014
1.36
2.40
4.4
3.4
—
—
—
0
0
7
17
4.15
2.36
2.0
2.7
—
—
—
0
0
121
936
1.37
2.36
4.5
3.9
1057.62
323.88
ng/l
0.58
108
813
15
66
2.31
2.26
1.3
1.5
—
—
—
0
0
16
73
2.22
2.23
1.1
1.4
60653.00
34953.12
e6/l
0.26
11
48
58
396
1.51
2.22
10.6
7.9
—
—
—
0
0
5
9
5.59
2.21
2.0
2.4
58700.00
39222.22
ug/l
—
5
9
17
80
2.16
2.20
1.6
1.5
—
—
—
0
0
8
24
3.36
2.18
1.6
1.3
86.38
89.87
umol/l
—
8
24
74
534
1.44
2.16
1.4
1.3
—
—
—
0
0
23
123
1.90
2.14
1.3
1.6
241.71
257.98
ug/g
0.14
14
74
75
544
1.43
2.13
7.2
7.1
1.50
0.95
mmol/l
0.61
58
431
131
1043
1.33
2.11
2.8
3.0
—
—
—
0
0
152
1242
1.30
2.02
2.6
3.2
35.02
32.49
u/l
0.50
140
1179
35
218
1.64
1.99
1.1
1.3
—
—
—
0
0
98
756
1.35
1.95
3.4
3.1
1.71
2.66
e6/l
0.62
54
419
5
11
4.57
1.94
1.2
1.1
—
—
—
0
0
74
545
1.41
1.94
7.3
7.0
5.13
5.08
kpa
0.17
69
514
74
545
1.41
1.94
7.2
7.0
11.09
11.99
kpa
1.16
67
516
40
260
1.58
1.92
3.4
2.7
10.60
10.36
g/l
0.10
34
237
30
182
1.68
1.89
1.1
1.2
193.68
149.67
iu/ml
0.23
13
62
28
167
1.71
1.87
1.8
1.6
—
—
—
0
0
14
66
2.15
1.83
1.3
1.2
—
—
—
0
0
7
23
3.07
1.80
1.3
1.2
—
—
—
0
0
29
177
1.67
1.79
1.2
1.3
—
—
—
0
0
18
95
1.92
1.77
1.7
1.6
47728.10
18472.81
e6/l
—
10
69
36
234
1.57
1.75
7.2
3.7
23.35
24.08
mmol/l
0.79
36
227
8
30
2.69
1.73
1.1
1.2
—
—
—
0
0
7
24
2.94
1.72
3.4
4.3
—
—
—
0
0
26
156
1.70
1.72
1.4
1.2
333.24
224.05
u/ml
0.26
26
141
14
68
2.08
1.71
1.2
1.7
—
—
—
0
0
24
141
1.73
1.70
4.1
2.6
0.74
0.23
g/l
0.99
12
50
65
482
1.39
1.66
5.7
3.4
1.45
1.93
mmol/l
0.48
55
391
52
371
1.44
1.65
1.3
1.3
—
—
—
0
0
24
143
1.71
1.63
3.2
2.5
37.62
36.93
g/l
0.25
16
130
22
128
1.75
1.62
4.5
3.3
—
—
—
0
0
22
128
1.75
1.62
6.2
11.4
—
—
—
0
0
10
42
2.40
1.62
3.5
2.4
—
—
—
0
0
34
223
1.56
1.60
2.5
2.4
—
—
—
0
0
15
77
1.97
1.60
1.3
2.2
—
—
—
0
0
11
50
2.22
1.57
1.5
6.3
7.08
7.41
mmol/l
0.19
11
44
64
480
1.37
1.54
5.2
3.4
5.89
5.76
kpa
0.36
64
464
56
414
1.39
1.47
1.3
1.3
913.33
468.17
titre
0.39
12
71
54
400
1.38
1.41
2.4
2.4
30.96
33.36
u/l
0.32
46
343
116
960
1.26
1.39
3.3
3.2
0.61
0.79
ug/l
2.90
83
667
11
53
2.10
1.39
1.0
1.1
—
—
—
0
0
64
489
1.35
1.39
2.3
2.5
7.71
8.92
umol/l
0.31
55
423
6
23
2.62
1.37
1.2
1.3
5.83
1.88
u/field
—
6
17
42
300
1.43
1.35
3.2
4.1
—
—
—
0
0
53
399
1.36
1.27
3.5
2.6
4.75
4.51
kpa
0.32
53
387
10
49
2.06
1.22
1.2
1.2
—
—
—
0
0
14
78
1.81
1.22
1.4
1.8
—
—
—
0
0
5
19
2.64
1.22
4.8
2.6
—
—
—
0
0
8
37
2.18
1.22
1.1
1.1
309.88
312.00
nmol/l
—
8
31
10
50
2.02
1.17
2.9
2.7
—
—
—
0
0
48
362
1.35
1.16
2.4
1.8
122.48
138.07
ug/g
0.17
39
281
0
35
0.00
1.15
0.0
1.5
—
—
—
0
0
0
35
0.00
1.15
0.0
1.5
—
—
—
0
0
102
853
1.24
1.13
4.3
4.3
1.02
1.02
kg/l
0.62
20
130
18
111
1.64
1.13
2.8
2.8
—
—
—
0
0
14
83
1.70
1.02
1.2
1.2
—
90.00
—
0
5
13
76
1.73
0.99
2.5
1.7
2.78
4.96
iu/l
—
5
23
17
108
1.59
0.97
1.8
1.3
—
—
—
0
0
6
30
2.01
0.87
8.5
2.9
—
—
—
0
0
11
64
1.73
0.86
1.1
1.4
—
—
—
0
0
6
32
1.88
0.82
1.0
1.1
—
—
—
0
0
32
242
1.34
0.80
9.6
9.7
—
—
—
0
0
15
98
1.54
0.79
3.8
3.7
39.56
29.90
mg/l
—
9
69
23
166
1.40
0.76
4.0
3.9
—
—
—
0
0
5
24
2.09
0.74
1.0
1.3
—
—
—
0
0
10
60
1.68
0.72
1.8
1.6
—
—
—
0
0
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
13
85
1.54
0.69
1.2
1.1
—
—
—
0
0
16
110
1.47
0.69
1.1
1.2
0.38
1.05
u/ml
—
5
11
33
259
1.29
0.67
1.4
1.4
—
—
—
0
0
11
70
1.58
0.65
3.0
2.9
59.55
61.33
%
0.16
11
70
37
296
1.27
0.65
1.8
1.4
—
—
—
0
0
10
62
1.62
0.65
1.2
1.2
—
—
—
0
0
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
32
254
1.27
0.61
3.8
3.0
24.94
25.19
mmol/l
0.15
32
247
0
20
0.00
0.60
0.0
1.4
—
136.15
—
0
20
0
21
0.00
0.60
0.0
1.0
—
0.60
—
0
12
11
72
1.54
0.59
1.0
1.1
—
—
—
0
0
16
114
1.41
0.59
1.3
1.2
—
—
—
0
0
7
115
0.60
0.58
1.3
1.5
—
—
—
0
0
41
338
1.23
0.58
1.6
1.6
—
—
—
0
0
6
36
1.67
0.57
1.2
1.2
—
—
—
0
0
62
536
1.17
0.54
1.4
1.2
36.88
44.70
iu/ml
0.24
18
164
6
40
1.50
0.51
6.2
2.3
—
—
—
0
0
10
67
1.50
0.50
1.2
1.7
—
—
—
0
0
11
155
0.70
0.49
1.1
1.4
—
—
—
0
0
7
46
1.53
0.48
3.6
2.6
—
—
—
0
0
10
68
1.48
0.47
3.1
2.7
4.17
4.36
e9/l
—
10
68
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.80
—
0
9
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
58
520
1.13
0.34
1.3
1.2
2.16
16.06
u/ml
2.89
21
173
6
44
1.37
0.34
1.5
1.2
—
—
—
0
0
7
55
1.28
0.30
1.3
1.4
—
280.66
—
0
21
103
971
1.07
0.24
1.6
1.6
1.30
1.35
mmol/l
0.30
82
811
36
322
1.13
0.24
3.6
2.9
123.11
127.21
g/l
0.52
36
314
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
3.1
—
29.38
—
0
13
6
48
1.25
0.20
6.2
2.1
—
—
—
0
0
6
48
1.25
0.20
6.3
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
5.14
—
0
7
0
14
0.00
0.20
0.0
3.2
—
—
—
0
0
6
49
1.23
0.20
6.2
2.0
—
—
—
0
0
6
49
1.23
0.20
6.3
2.0
—
—
—
0
0
6
49
1.23
0.20
6.2
2.0
—
—
—
0
0
28
251
1.12
0.19
2.9
4.1
—
—
—
0
0
5
70
0.71
0.16
2.2
1.8
—
—
—
0
0
13
111
1.17
0.16
1.2
1.2
—
—
—
0
0
6
79
0.76
0.15
1.2
1.3
—
—
—
0
0
9
80
1.13
0.15
1.7
2.7
—
—
—
0
0
8
100
0.80
0.13
1.1
1.2
—
—
—
0
0
21
191
1.10
0.12
2.9
3.2
9018.38
1538.60
u/ml
0.38
16
164
13
146
0.89
0.10
2.3
4.9
—
—
—
0
0
5
45
1.11
0.10
1.2
1.2
—
—
—
0
0
27
252
1.07
0.09
1.2
1.2
—
—
—
0
0
5
61
0.82
0.08
2.0
1.7
208.20
219.22
pmol/l
—
5
55
8
91
0.88
0.07
1.0
1.1
—
—
—
0
0
10
90
1.11
0.05
3.8
2.1
70.40
60.03
%
—
10
90
19
183
1.04
0.01
1.3
1.3
—
—
—
0
0
11
114
0.96
0.00
3.5
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
2.6
2.4
—
—
—
0
0
6
59
1.02
-0.00
1.7
1.3
9.15
6.77
mmol/l
—
6
54
0
7
0.00
-0.00
0.0
1.1
—
1.79
—
0
7
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
5
51
0.98
-0.00
1.8
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
40.90
—
0
5
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.4
—
—
—
0
0
6
65
0.92
-0.00
7.2
3.8
52.67
41.81
u/ml
—
6
65
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_LENSDISLOCATIO and mortality.

Females

Parameter HR [95% CI] p-value
H7_LENSDISLOCATIO 1.052 [0.92, 1.2] 0.453
Birth year 0.994 [0.99, 1.0] 0.142

During the follow-up period (1.1.1998 — 31.12.2019), 976 out of 2298 females with H7_LENSDISLOCATIO died.

Males

Parameter HR [95% CI] p-value
H7_LENSDISLOCATIO 1.095 [0.92, 1.3] 0.293
Birth year 0.986 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 628 out of 1783 males with H7_LENSDISLOCATIO died.

Mortality risk

Mortality risk for people of age

years, who have H7_LENSDISLOCATIO.

N-year risk Females Males
1 0.085% 0.2%
5 0.743% 1.17%
10 1.606% 3.076%
15 2.894% 5.677%
20 5.148% 10.003%

Relationships between endpoints

Index endpoint: H7_LENSDISLOCATIO – Dislocation of lens

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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