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Lumbosacral root disorders, not elsewhere classified

DOID EFO Endpoint Browser PheWeb

G6_LSROOT

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G54.4
  • Hospital discharge: ICD-9 — 3534
  • Cause of death: ICD-10 — G54.4
  • Cause of death: ICD-9 — 3534

2 out of 7 registries used, show all original rules.

448

4. Check minimum number of events

None

448

5. Include endpoints

None

448

6. Filter based on genotype QC (FinnGen only)

439

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G54
Name in latin
Morbositates radicum nervorum lumbosacralium non alibi classificatae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3586 1888 1683
Only index persons 3295 1778 1517
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.05
Only index persons 0.06 0.07 0.06
Median age at first event (years)
Whole population 57.09 56.62 57.51
Only index persons 56.44 55.99 56.96

-FinnGen-

Key figures

All Female Male
Number of individuals 439 255 184
Unadjusted period prevalence (%) 0.09 0.09 0.08
Median age at first event (years) 54.83 52.33 58.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
448
Matched controls
4480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G54.4
ICD-10 Finland
Lumbosacral root disorders, not elsewhere classified
12682.3
307.7
369
*
XA402
NOMESCO Finland
ENMG
190.7
307.7
236
26
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
9.9
123.9
195
325
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
8.2
110.4
224
487
N03AX16
ATC
[U] pregabalin
7.6
104.5
243
602
M48.0
ICD-10 Finland
Spinal stenosis
8.0
90.3
158
287
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
7.6
85.2
156
296
N03AX12
ATC
[U] gabapentin; oral
6.7
79.1
170
376
M54.1
ICD-10 Finland
Radiculopathy
12.7
72.5
76
71
M54.4
ICD-10 Finland
Lumbago with sciatica
6.1
72.3
174
424
3534A
ICD-9 Finland
Nerve root and plexus disorders, Lumbosacral root lesions, not elsewhere classified[RADICULOPATHIA LUMBOSACRALIS]
+∞
71.8
67
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
12.3
59.7
63
59
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
8.2
56.3
83
121
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
7.3
50.3
82
133
Z01.9
ICD-10 Finland
Special examination, unspecified
7.5
49.9
79
124
N06AA09
ATC
amitriptyline; systemic
6.0
49.9
104
216
M54.5
ICD-10 Finland
Low back pain
4.1
48.3
248
1039
N06AX21
ATC
duloxetine; oral
5.4
46.2
108
248
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
174.5
45.8
47
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
8.3
45.7
65
90
N02AX02
ATC
tramadol; systemic, rectal
3.8
42.0
279
1353
ACC51
NOMESCO Finland
Release of median nerve
387.0
36.5
36
*
Z50.1
ICD-10 Finland
Other physical therapy
6.9
36.2
60
98
L03
ICPC
Low back symptom/complaint
3.5
35.6
183
736
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
7.6
34.7
52
76
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.2
34.5
81
184
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.6
34.0
95
249
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
45.0
33.7
41
10
L28
ICPC
Limited function/disability (L)
3.8
33.4
135
462
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.2
33.4
107
311
N02AA05
ATC
oxycodone; systemic
3.7
32.7
135
468
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.6
32.7
90
233
M47.9
ICD-10 Finland
Spondylosis, unspecified
10.0
31.3
37
40
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.8
29.9
39
48
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
11.4
29.9
32
30
M43.1
ICD-10 Finland
Spondylolisthesis
6.7
29.6
50
83
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
8.0
28.9
41
56
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
27.0
204
995
R29
ICPC
Respiratory symptom/complaint other
4.9
26.1
62
141
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
7.3
25.5
39
58
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
24.5
250
1406
A29
ICPC
General symptom/complaint other
3.5
24.5
99
333
N02BF01
ATC
gabapentin; oral
4.6
24.3
63
154
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.0
24.0
145
619
M01AH01
ATC
celecoxib; oral
3.1
23.8
125
493
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
30.1
23.5
31
11
A02BC05
ATC
esomeprazole; systemic
2.7
23.4
235
1303
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
5.2
23.0
50
105
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.0
22.9
36
55
A02BC03
ATC
lansoprazole; oral
2.7
22.3
182
905
N06AX16
ATC
venlafaxine; oral
3.3
21.9
96
338
N02BF02
ATC
pregabalin; oral
4.9
21.9
51
114
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
4.2
21.3
62
165
M79.6
ICD-10 Finland
Pain in limb
2.6
21.1
227
1282
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.5
20.9
42
82
WX702
NOMESCO Finland
Supraglottic ventilation device
4.6
20.9
53
127
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
20.4
142
647
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.7
20.3
142
648
K30
ICD-10 Finland
Functional dyspepsia
3.5
20.0
80
265
M01AH05
ATC
etoricoxib; oral
2.7
19.9
320
2160
XG410
NOMESCO Finland
Flow-volume spirometry
5.6
19.7
39
75
S02.5
ICD-10 Finland
Fracture of tooth
6.7
19.5
32
51
M03BX02
ATC
tizanidine; oral
2.6
19.4
313
2105
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.5
19.0
74
241
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.1
18.9
29
43
A06AD11
ATC
lactulose; oral
3.0
18.8
96
368
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
18.8
224
1307
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
14.4
18.5
31
23
Z02.7
ICD-10 Finland
Issue of medical certificate
4.2
18.4
53
140
9211
FHL
Exploration or removal of diskusprolapse
7.3
18.0
27
39
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
6.0
18.0
33
59
WX704
NOMESCO Finland
Intubation
4.0
17.8
54
148
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
7.7
17.5
25
34
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
19.6
17.5
26
14
R52.2
ICD-10 Finland
Other chronic pain
6.0
17.5
32
57
N03AX09
ATC
lamotrigine; oral
5.3
17.4
36
72
M01AC06
ATC
meloxicam; systemic, rectal
2.3
17.2
207
1200
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
6.6
16.9
28
45
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
36.6
16.8
21
6
A02BC02
ATC
pantoprazole; systemic
2.6
16.6
339
2452
M54.3
ICD-10 Finland
Sciatica
4.3
16.4
45
114
Z00.6
ICD-10 Finland
Examination for normal comparison and control in clinical research programme
13.5
16.4
28
22
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
16.3
142
710
L29
ICPC
Musculoskeletal sympt/complt other
3.5
16.3
60
188
M25.5
ICD-10 Finland
Pain in joint
2.3
16.1
171
934
M01AB05
ATC
diclofenac; systemic, rectal
2.5
16.0
329
2367
S29
ICPC
Skin symptom/complaint other
2.7
16.0
108
478
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
6.9
15.9
25
38
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
5.7
15.6
30
56
NG1EA, ,
SPAT
39.6
15.5
19
5
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.6
15.4
114
527
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
15.3
157
841
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.7
15.2
36
81
M01AH02
ATC
rofecoxib; oral
2.9
14.9
81
319
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.0
14.3
70
260
M01AE02
ATC
naproxen; oral, rectal
2.2
14.3
278
1911
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
14.3
60
204
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.1
14.2
65
232
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
44.0
14.2
17
*
N03AE01
ATC
clonazepam; systemic
4.2
14.2
39
99
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.6
14.1
49
147
M54.8
ICD-10 Finland
Other dorsalgia
5.1
14.0
30
62
XA420
NOMESCO Finland
Extensive sleep examination
14.2
13.9
23
17
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
13.9
153
839
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.2
13.8
29
59
K29
ICPC
Cardiovascular sympt/complt other
4.4
13.7
35
84
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
22.0
13.4
19
9
R07.3
ICD-10 Finland
Other chest pain
3.0
13.3
63
229
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
5.3
13.1
27
54
J01FA09
ATC
clarithromycin; systemic
2.2
13.0
161
920
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.7
13.0
76
311
J01MA02
ATC
ciprofloxacin; systemic
2.1
12.9
198
1228
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
12.8
196
1214
GX2C5
NOMESCO Finland
Short-lasting oximetry
33.1
12.6
16
5
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.4
12.6
47
148
3534B
ICD-9 Finland
Nerve root and plexus disorders, Lumbosacral root lesions, not elsewhere classified[SYNDROMA CAUDAE EQUINAE]
+∞
12.6
12
*
H02AB06
ATC
prednisolone; systemic
2.0
12.4
233
1550
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
12.3
86
383
A28
ICPC
Limited function/disability NOS
2.4
12.3
96
451
M01AE11
ATC
tiaprofenic acid; oral, rectal
4.3
12.3
32
78
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.7
12.0
72
297
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.4
12.0
31
75
M01AX17
ATC
nimesulide; oral
2.2
11.9
131
712
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
11.8
84
378
M01AX05
ATC
glucosamine; oral
2.3
11.7
113
581
G45.4
ICD-10 Finland
Transient global amnesia
5.5
11.7
23
44
M70.6
ICD-10 Finland
Trochanteric bursitis
2.6
11.5
76
329
35399
ICD-8 Finland
Sciatica
+∞
11.5
11
*
R1280
NOMESCO Finland
Evaluation of the need for vocational rehabilitation
+∞
11.5
11
*
R05
ICPC
Cough
2.2
11.4
126
683
M79.7
ICD-10 Finland
Fibromyalgia
4.5
11.4
28
65
KMAK, ,
NOMESCO Finland
2.0
11.4
233
1582
P03
ICPC
Feeling depressed
3.1
11.2
49
170
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
11.2
102
511
M50.3
ICD-10 Finland
Other cervical disc degeneration
10.4
11.1
21
21
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
11.0
217
1449
N05CD07
ATC
temazepam; oral
2.6
11.0
69
291
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
11.0
151
888
S18
ICPC
Laceration/cut
2.0
10.9
220
1480
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
18.4
10.8
16
9
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.3
10.8
43
141
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
13.3
10.7
18
14
S02.51
ICD-10 Finland
Fracture of tooth, open
2.6
10.7
66
276
ABC99
NOMESCO Finland
Other decompressive operation on spinal cord or nerve root
61.5
10.7
12
*
H57.1
ICD-10 Finland
Ocular pain
4.5
10.7
26
60
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
10.6
77
349
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
16.5
10.4
16
10
S59
ICPC
Skin, Other therap proced/minor surg NEC
9.1
10.4
21
24
R51.80
ICD-10 Finland
Headache
2.4
10.4
77
352
S06.0
ICD-10 Finland
Concussion
2.6
10.1
62
258
B01AB10
ATC
tinzaparin; parenteral
2.6
10.1
65
277
J01DB01
ATC
cefalexin; oral
2.3
10.1
375
3083
L15
ICPC
Knee symptom/complaint
2.1
10.0
121
675
M54.2
ICD-10 Finland
Cervicalgia
3.0
10.0
46
164
R06AE07
ATC
cetirizine; oral
1.9
10.0
199
1321
G56.2
ICD-10 Finland
Lesion of ulnar nerve
17.2
9.9
15
9
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.3
9.9
38
122
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.4
9.8
78
367
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.3
9.8
82
395
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.5
9.8
65
282
R96
ICPC
Asthma
2.7
9.7
54
214
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
56.2
9.7
11
*
K59.09
ICD-10 Finland
Constipation, unspecified
3.1
9.7
42
145
N02BE01
ATC
paracetamol; systemic, rectal
2.8
9.6
407
3493
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
9.6
93
476
WZA90
NOMESCO Finland
Other medical or dental certificate
2.1
9.6
113
624
L86
ICPC
Back syndrome with radiating pain
3.4
9.5
35
109
J01DA01
ATC
[U] cefalexin
1.9
9.5
285
2146
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
9.5
151
927
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
30.7
9.4
12
*
UKC02
NOMESCO Finland
Cystoscopy
2.2
9.4
87
436
R42
ICD-10 Finland
Dizziness and giddiness
2.1
9.4
112
621
EC1VA, ,
NOMESCO Finland
4.2
9.4
25
62
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
3.2
9.3
37
121
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.9
9.3
46
171
G54.0
ICD-10 Finland
Brachial plexus disorders
14.1
9.2
15
11
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
8.0
9.2
20
26
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.4
9.1
68
311
XQ800
NOMESCO Finland
Prick test
3.0
9.0
40
140
D29
ICPC
Digestive symptom/complaint other
4.8
8.9
20
43
M01AB16
ATC
aceclofenac; oral
4.3
8.8
23
56
ZY010
NOMESCO Finland
Hospital outpatient
3.7
8.8
28
79
UJF32
NOMESCO Finland
Coloscopy
1.9
8.8
134
808
N05CF01
ATC
zopiclone; oral
1.9
8.8
161
1032
TAB20
NOMESCO Finland
Epidural puncture
14.4
8.7
14
10
SFA10
NOMESCO Finland
One-surface restoration
1.8
8.7
245
1788
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
8.7
52
214
L01
ICPC
Neck symptom/complaint
2.3
8.7
72
345
R52.1
ICD-10 Finland
Chronic intractable pain
16.7
8.6
13
8
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
16.7
8.6
13
8
S04
ICPC
Lump/swelling localized
2.7
8.6
49
197
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
8.5
59
261
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.8
8.4
19
41
D07AD01
ATC
clobetasol; topical
2.1
8.4
86
448
R52.9
ICD-10 Finland
Pain, unspecified
2.5
8.4
54
230
Z01.2
ICD-10 Finland
Dental examination
1.8
8.4
199
1376
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
8.4
131
795
G54.2
ICD-10 Finland
Cervical root disorders, not elsewhere classified
+∞
8.4
8
*
G51.0
ICD-10 Finland
Bell palsy
+∞
8.4
8
*
A01
ICPC
Pain general/multiple sites
2.6
8.3
50
206
GD1AA, ,
SPAT
2.3
8.3
65
303
ZXA05
NOMESCO Finland
Left side
1.9
8.3
120
709
1220
FHL
Arthroscopy
3.6
8.2
27
78
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.5
8.2
29
88
M22.4
ICD-10 Finland
Chondromalacia patellae
4.9
8.2
18
38
GX1E5, ,
SPAT
12.0
8.1
14
12
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
8.1
39
143
ZYC05, ,
SPAT
10.3
8.1
15
15
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
8.0
107
614
R03BA01
ATC
beclometasone; inhalant
2.2
8.0
71
349
N06AX11
ATC
mirtazapine; oral
1.8
8.0
157
1022
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
7.9
100
563
R43
ICPC
Respiratory, Other diagnostic procedure
8.7
7.9
16
19
N04BC05
ATC
pramipexole; oral
2.6
7.9
46
187
M35.7
ICD-10 Finland
Hypermobility syndrome
9.7
7.8
15
16
L16
ICPC
Ankle symptom/complaint
2.4
7.8
58
264
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
4.3
7.8
20
48
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
7.8
123
746
J01CA04
ATC
amoxicillin; systemic
2.0
7.8
355
2955
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
4.0
7.8
22
57
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.6
7.8
26
76
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
7.8
61
285
XG405, ,
SPAT
15.4
7.8
12
8
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
15.4
7.8
12
8
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
7.7
310
2476
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
7.7
243
1811
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
18.7
7.6
11
6
SFA00
NOMESCO Finland
Small restoration
2.2
7.6
67
328
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
9.1
7.6
15
17
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
7.6
116
697
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.6
7.5
45
185
XF404
NOMESCO Finland
Ambulatory ECG
2.5
7.5
51
223
D01
ICPC
Abdominal pain/cramps general
2.4
7.5
55
249
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
7.5
305
2436
M01AE01
ATC
ibuprofen; systemic, rectal
2.4
7.5
403
3534
N42.9
ICD-10 Finland
Disorder of prostate, unspecified
7.9
7.4
16
21
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
81.4
7.4
8
*
NH1FA, ,
SPAT
81.4
7.4
8
*
JN3AE, ,
SPAT
3.7
7.4
23
64
D19
ICPC
Teeth/gum symptom/complaint
1.9
7.4
126
782
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.6
7.4
45
187
H13
ICPC
Plugged feeling ear
2.0
7.3
94
531
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.7
7.3
41
163
M01AB55
ATC
diclofenac, combinations; oral
2.7
7.3
41
163
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
7.3
7
*
J01MA12
ATC
levofloxacin; systemic
2.0
7.3
93
524
R03DC03
ATC
montelukast; oral
2.1
7.3
79
420
ZX109, ,
SPAT
16.1
7.3
11
7
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
4.6
7.2
17
38
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
8.1
7.2
15
19
NE1AA, ,
SPAT
8.1
7.2
15
19
M24.2
ICD-10 Finland
Disorder of ligament
8.1
7.2
15
19
B01AX05
ATC
fondaparinux; parenteral
12.3
7.1
12
10
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
7.1
55
255
UJD10, ,
SPAT
4.3
7.1
18
43
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.3
7.1
18
43
M02AA07
ATC
piroxicam; topical
1.7
7.0
165
1124
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
4.5
7.0
17
39
L17
ICPC
Foot/toe symptom/complaint
1.8
7.0
127
802
U29
ICPC
Urinary symptom/complaint other
3.8
7.0
21
57
ZX100
NOMESCO Finland
Oral
6.0
7.0
18
31
C07AB07
ATC
bisoprolol; oral
1.7
7.0
228
1699
J01EA01
ATC
trimethoprim; systemic
1.8
6.9
123
771
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.6
6.9
23
67
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
14.1
6.9
11
8
P01AB01
ATC
metronidazole; oral, rectal
1.7
6.9
187
1323
J01AA04
ATC
lymecycline; systemic
2.2
6.9
60
292
HA1AA, ,
SPAT
5.8
6.8
18
32
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.7
6.8
36
139
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
6.8
93
536
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.6
6.8
22
63
F34.1
ICD-10 Finland
Dysthymia
3.4
6.8
24
73
-50
ICPC
Medication/prescr/renewal
3.5
6.8
23
68
K02.1
ICD-10 Finland
Caries of dentine
1.7
6.8
248
1899
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.7
6.7
36
140
R02
ICPC
Shortness of breath/dyspnoea
2.2
6.7
61
303
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.7
6.7
21
59
R05FA02
ATC
opium derivatives and expectorants; systemic
1.7
6.6
189
1352
R2110
NOMESCO Finland
Giving the first information
2.7
6.6
35
135
ND2AA, ,
SPAT
3.1
6.6
27
90
R1250
NOMESCO Finland
Evaluation of functional capability
4.3
6.6
17
41
Z04.3
ICD-10 Finland
Examination and observation following other accident
4.3
6.6
17
41
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
6.6
171
1193
R35
ICD-10 Finland
Polyuria
2.6
6.5
38
154
JAH01
NOMESCO Finland
Laparoscopy
3.3
6.5
25
80
R03AC02
ATC
salbutamol; inhalant
1.7
6.5
242
1852
M20.2
ICD-10 Finland
Hallux rigidus
3.3
6.5
24
75
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.0
6.5
18
46
M77.4
ICD-10 Finland
Metatarsalgia
2.7
6.5
34
131
S76
ICPC
Skin infection other
2.9
6.5
30
108
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
6.4
41
174
K07.60
ICD-10 Finland
Snapping jaw
3.3
6.4
24
76
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.7
6.4
20
56
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.7
6.4
20
56
M23.3
ICD-10 Finland
Other meniscus derangements
6.7
6.4
15
23
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
3.4
6.4
23
71
J01AA02
ATC
doxycycline; systemic
1.8
6.4
352
2991
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.9
6.3
18
47
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.3
121
774
G50.1
ICD-10 Finland
Atypical facial pain
18.3
6.3
9
5
G58.8
ICD-10 Finland
Other specified mononeuropathies
+∞
6.3
6
*
XG412, ,
SPAT
27.1
6.2
8
*
RTGOM, ,
NOMESCO Finland
27.1
6.2
8
*
7240B
ICD-9 Finland
Other and unspecified disorders of back, Spinal stenosis, other than cervical[STENOSIS CANALIS SPINALIS LUMBOSACRALIS]
27.1
6.2
8
*
NH3FA, ,
SPAT
27.1
6.2
8
*
B01AB05
ATC
enoxaparin; parenteral
1.7
6.2
148
1005
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
6.2
41
177
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
6.2
70
377
C03CA01
ATC
furosemide; systemic
1.7
6.2
137
912
R06AE09
ATC
levocetirizine; oral
2.1
6.1
63
328
L08
ICPC
Shoulder symptom/complaint
1.8
6.1
95
570
ZXA00
NOMESCO Finland
Right side
1.8
6.1
120
773
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
6.1
62
322
XG460
NOMESCO Finland
Short time oxymetry
5.7
6.0
16
29
Y96.9
ICD-10 Finland
Unspecified type of accident
6.2
6.0
15
25
N05BA12
ATC
alprazolam; oral
2.2
6.0
51
246
R06.0
ICD-10 Finland
Dyspnoea
1.7
6.0
121
784

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
74
8.33
39.49
1.9
2.3
—
—
—
0
0
66
140
5.36
30.29
1.9
1.7
—
—
—
0
0
186
936
2.69
22.24
8.3
6.9
—
—
—
0
0
102
397
3.03
19.53
3.7
2.7
8.03
9.82
umol/l
0.31
94
347
69
218
3.56
18.54
2.3
2.3
—
—
—
0
0
59
170
3.85
18.14
2.0
3.5
—
—
—
0
0
248
1635
2.16
14.15
5.3
5.5
1.21
1.21
mmol/l
0.03
233
1487
216
1393
2.06
12.59
4.3
3.5
26.73
34.60
ng/l
0.92
179
978
249
1707
2.03
12.09
10.5
13.2
1.18
1.26
inr
0.56
45
500
289
2093
2.07
12.01
5.0
4.5
6.64
6.67
mmol/l
0.09
280
1970
255
1794
1.98
11.16
5.5
6.6
1.22
1.21
mmol/l
0.03
235
1528
50
182
2.97
10.52
5.8
9.7
24.62
24.59
mmol/l
0.02
50
177
175
1105
1.96
10.30
4.0
3.8
7.39
7.40
ph
0.37
12
220
339
2679
2.09
10.16
4.7
3.9
11.42
12.43
mm/h
0.83
324
2453
110
599
2.11
9.69
1.4
1.2
17.27
37.03
iu/ml
2.48
43
202
68
321
2.32
8.45
5.5
6.5
1.24
1.33
mmol/l
0.34
68
314
101
559
2.04
8.42
1.3
1.2
14.68
13.64
u/ml
0.04
28
229
232
1690
1.77
8.09
5.6
5.7
56.68
57.22
%
0.31
223
1581
112
664
1.92
7.60
3.2
3.9
517.66
255.62
ng/l
0.54
80
522
231
1702
1.74
7.57
5.7
6.0
28.16
27.49
%
0.43
224
1591
227
1665
1.74
7.55
5.7
5.8
3.01
2.78
%
1.02
218
1550
227
1676
1.72
7.29
6.2
6.1
8.62
8.76
%
0.30
219
1563
237
1771
1.72
7.28
5.6
5.6
0.59
0.58
e9/l
0.21
220
1519
241
1811
1.72
7.23
5.6
5.6
1.87
1.91
e9/l
0.20
224
1593
243
1831
1.71
7.21
6.0
6.0
0.20
0.19
e9/l
0.75
226
1601
87
481
2.00
7.20
1.2
1.2
—
—
—
0
0
220
1615
1.71
7.18
5.5
5.8
0.70
0.68
%
0.36
213
1496
237
1776
1.71
7.16
5.6
5.6
0.04
0.04
e9/l
0.81
220
1525
220
1639
1.67
6.61
2.5
2.5
—
—
—
0
0
72
389
2.01
6.32
5.8
7.7
1.70
1.30
mmol/l
0.39
55
312
290
2341
1.68
6.24
4.8
4.2
9.60
2431.94
e6/l
—
5
48
134
899
1.70
5.84
3.8
3.8
94.59
92.08
%
0.50
128
877
59
1041
0.50
5.84
1.9
1.6
1.48
1.36
mmol/l
0.44
49
867
78
446
1.91
5.80
1.2
1.3
411.43
576.25
titre
0.56
14
96
355
3056
1.78
5.73
22.9
18.1
331.35
332.19
g/l
1.01
355
3033
400
3595
2.05
5.36
19.3
13.9
21.81
23.75
mg/l
0.53
354
2817
333
2838
1.68
5.32
7.8
7.6
76.65
78.56
u/l
0.42
320
2660
139
962
1.65
5.31
4.3
4.2
—
—
—
0
0
297
2467
1.60
5.20
4.2
4.0
—
—
—
0
0
152
1083
1.61
5.14
3.6
2.9
2171.36
1151.50
ng/l
0.48
134
934
240
1913
1.55
4.91
5.6
6.6
11.75
11.44
umol/l
0.09
230
1821
154
1111
1.59
4.90
2.7
2.5
49.51
62.17
u/l
2.06
148
1029
259
2104
1.55
4.83
8.6
9.5
4.52
4.05
e9/l
0.37
241
1825
119
809
1.64
4.82
3.0
3.4
—
—
—
0
0
149
1072
1.58
4.78
1.9
2.1
248.08
188.85
u/l
0.37
141
1005
152
1103
1.57
4.68
2.8
2.9
—
—
—
0
0
13
26
5.12
4.66
1.1
1.1
—
—
—
0
0
313
2668
1.57
4.59
3.9
3.8
—
—
—
0
0
89
572
1.69
4.44
3.0
2.7
0.98
2.31
e6/l
2.64
74
302
194
1503
1.51
4.37
2.1
2.1
—
—
—
0
0
99
1403
0.62
4.18
2.5
2.9
—
—
—
0
0
205
1631
1.47
3.93
8.3
9.2
0.22
0.00
e9/l
0.49
186
1340
125
901
1.54
3.86
1.3
1.3
—
—
—
0
0
11
330
0.32
3.85
1.3
1.5
—
—
—
0
0
208
1673
1.45
3.71
5.7
6.1
—
—
—
0
0
188
1489
1.45
3.61
2.0
1.9
93.90
95.20
pmol/l
0.15
102
769
408
3787
1.87
3.56
16.3
13.2
—
—
—
0
0
14
46
3.11
3.56
1.8
3.5
—
—
—
0
0
9
17
5.38
3.52
1.6
1.4
—
—
—
0
0
15
52
2.95
3.49
1.5
1.3
—
—
—
0
0
42
233
1.89
3.43
2.1
2.4
—
—
—
0
0
129
960
1.48
3.37
3.2
2.9
—
—
—
0
0
72
476
1.61
3.20
2.0
2.3
23.56
23.65
%
0.01
61
413
80
545
1.57
3.14
2.1
2.3
13.79
13.38
umol/l
0.17
72
506
185
1491
1.41
3.11
2.1
2.2
76.72
77.89
nmol/l
0.25
173
1334
116
865
1.46
2.96
1.5
1.5
22.82
20.80
nmol/l
0.64
102
731
19
82
2.38
2.95
1.1
1.2
—
—
—
0
0
75
512
1.56
2.91
2.0
2.2
2.33
2.34
g/l
0.08
69
475
121
917
1.44
2.83
2.0
2.6
345.16
6841.95
umol/l
3.65
111
793
414
3903
1.80
2.81
20.9
16.4
76.76
76.98
umol/l
0.04
414
3903
16
66
2.48
2.74
1.1
2.8
—
—
—
0
0
160
1282
1.39
2.70
3.3
3.5
79.95
74.00
e6/l
0.06
141
912
140
1097
1.40
2.70
3.2
3.0
36.89
128.87
e6/l
0.84
131
838
366
3360
1.49
2.70
5.1
4.6
1.81
2.29
mu/l
0.73
346
3052
128
990
1.41
2.66
3.2
2.9
0.23
0.53
e6/l
2.04
121
734
115
873
1.43
2.65
1.8
1.9
2.96
2.93
mg/l
0.05
105
745
5
9
5.60
2.22
1.0
1.3
—
—
—
0
0
50
334
1.56
2.16
2.8
2.2
33.42
33.00
u/l
0.03
36
277
28
161
1.79
2.11
3.7
3.2
—
—
—
0
0
31
184
1.74
2.10
2.0
2.3
—
—
—
0
0
13
56
2.36
2.06
1.5
1.8
—
—
—
0
0
6
15
4.04
2.04
1.0
1.0
—
—
—
0
0
10
227
0.43
1.98
2.4
3.0
123.90
128.29
g/l
—
10
221
13
58
2.28
1.92
1.5
1.4
—
—
—
0
0
100
782
1.36
1.90
1.8
1.7
1.34
1.27
mg/l
0.05
78
623
56
395
1.48
1.90
1.7
1.5
—
—
—
0
0
306
2788
1.31
1.89
4.6
3.8
14.80
14.81
pmol/l
0.02
292
2511
75
563
1.40
1.83
2.1
1.9
30.38
29.58
s
0.73
75
545
5
12
4.20
1.83
1.0
1.1
143.60
110.84
iu/ml
—
5
12
11
47
2.37
1.79
1.1
1.6
—
—
—
0
0
410
3929
1.51
1.67
11.4
10.4
26.26
25.56
u/l
0.36
401
3794
7
25
2.83
1.65
1.9
1.0
—
—
—
0
0
35
231
1.56
1.63
1.1
1.2
—
—
—
0
0
15
78
1.96
1.56
2.7
4.3
—
—
—
0
0
173
1497
1.25
1.52
2.9
2.5
113.35
129.90
ug/l
0.55
165
1373
80
1002
0.75
1.49
3.3
3.2
—
—
—
0
0
28
180
1.59
1.47
9.0
10.0
—
—
—
0
0
12
226
0.52
1.46
1.3
1.4
—
—
—
0
0
418
4040
1.52
1.41
25.0
20.5
40.06
40.21
%
0.23
410
3793
201
1781
1.23
1.40
3.3
3.5
0.00
0.00
estimate
-0.00
32
355
11
53
2.10
1.39
1.2
1.5
—
—
—
0
0
9
41
2.22
1.37
1.1
1.0
—
—
—
0
0
418
4043
1.51
1.37
25.5
20.5
7.38
6.56
e9/l
0.83
413
3919
14
75
1.89
1.36
1.1
1.3
—
—
—
0
0
418
4044
1.50
1.35
25.5
20.5
4.40
4.48
e12/l
2.58
413
3922
9
43
2.12
1.31
1.2
1.5
—
—
—
0
0
5
18
2.80
1.29
1.0
1.2
—
—
—
0
0
20
313
0.62
1.27
5.6
3.4
1.23
1.23
mmol/l
0.17
15
273
133
1138
1.24
1.26
2.2
2.3
—
—
—
0
0
380
3630
1.31
1.24
4.5
4.6
5.98
5.97
mmol/l
0.06
359
3313
11
56
1.99
1.23
1.1
1.0
—
—
—
0
0
5
19
2.65
1.22
1.0
1.3
98.63
190.61
mmol/24h
—
5
19
6
26
2.32
1.19
1.0
1.3
—
—
—
0
0
64
504
1.31
1.18
2.3
1.9
—
—
—
0
0
14
80
1.77
1.14
1.9
1.2
354.57
467.65
mg/l
1.28
14
74
89
737
1.26
1.12
1.1
1.2
0.54
2.41
u/ml
2.32
12
214
5
21
2.40
1.09
1.8
2.2
2.32
2.06
ug/l
—
5
16
15
89
1.71
1.09
1.6
1.7
6.02
6.17
iu/l
—
6
32
89
741
1.25
1.08
2.3
2.5
6.00
5.18
e6/l
0.19
82
677
9
48
1.89
1.01
1.1
1.1
—
—
—
0
0
7
35
2.02
1.00
1.6
1.3
—
—
—
0
0
14
84
1.69
0.99
2.3
1.8
—
—
—
0
0
9
50
1.82
0.97
1.1
1.3
—
—
—
0
0
198
1800
1.18
0.96
4.1
4.7
0.00
0.00
estimate
-0.00
31
335
57
703
0.78
0.95
2.1
2.9
0.61
0.74
ug/l
1.01
35
470
11
62
1.79
0.95
1.5
1.1
—
—
—
0
0
11
62
1.79
0.95
1.1
1.0
—
—
—
0
0
23
325
0.69
0.94
3.2
4.2
0.50
0.94
%
—
8
121
11
181
0.60
0.90
2.7
1.8
—
—
—
0
0
30
221
1.38
0.88
1.7
2.7
0.38
0.23
e6/l
0.42
30
213
84
983
0.82
0.88
4.5
3.8
0.00
0.00
estimate
-0.00
26
326
65
777
0.81
0.84
1.6
1.7
416.92
15798220.95
pmol/l
0.78
52
633
18
259
0.68
0.82
1.4
1.4
—
—
—
0
0
134
1193
1.18
0.82
4.2
4.8
1.69
2.55
ug/l
1.99
122
1067
198
1819
1.16
0.81
3.3
3.5
0.00
0.02
estimate
0.80
29
328
6
33
1.83
0.79
1.7
1.8
—
—
—
0
0
0
25
0.00
0.79
0.0
15.3
—
824.08
—
0
25
0
25
0.00
0.79
0.0
22.7
—
1694.88
—
0
25
22
302
0.71
0.78
3.3
4.3
0.00
0.11
%
—
7
98
6
34
1.77
0.76
2.0
2.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.4
—
—
—
0
0
56
462
1.24
0.76
3.7
5.3
1.06
1.03
mmol/l
0.33
56
422
21
288
0.72
0.75
3.2
4.1
0.14
0.62
%
—
7
99
7
38
1.86
0.74
1.6
1.3
—
—
—
0
0
37
291
1.30
0.74
5.2
7.3
10.81
9.96
mmol/l
0.29
37
272
15
100
1.52
0.73
1.5
2.3
14.45
12.32
mg/l
0.75
15
91
5
25
2.01
0.73
1.2
1.1
29.80
30.99
mg/l
—
5
20
171
1566
1.15
0.72
4.5
4.8
34.45
35.56
g/l
1.54
164
1462
5
26
1.93
0.71
1.0
1.3
—
—
—
0
0
18
249
0.71
0.69
1.1
1.3
—
—
—
0
0
7
42
1.68
0.68
1.4
1.4
—
—
—
0
0
17
119
1.45
0.68
2.3
2.1
180.76
535.11
ug/l
0.79
17
113
10
155
0.64
0.67
1.2
1.5
—
—
—
0
0
129
1421
0.87
0.65
3.1
3.3
5.80
5.78
ph
—
5
121
10
63
1.60
0.62
1.2
1.2
—
—
—
0
0
16
113
1.43
0.62
1.2
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
28
219
1.30
0.60
1.2
1.2
—
—
—
0
0
14
97
1.46
0.59
1.3
1.3
40.10
35.13
iu/l
0.21
14
84
0
22
0.00
0.59
0.0
2.3
—
493.27
—
0
15
49
413
1.21
0.57
1.3
1.3
—
—
—
0
0
48
404
1.21
0.57
1.2
1.6
—
—
—
0
0
88
782
1.16
0.56
3.9
3.8
1.02
1.02
kg/l
1.05
12
92
8
124
0.64
0.55
2.1
9.2
—
—
—
0
0
9
61
1.49
0.54
1.7
1.4
—
—
—
0
0
49
416
1.20
0.54
3.1
4.7
4.67
18.74
ug/l
0.75
38
345
9
62
1.46
0.53
1.1
1.3
—
—
—
0
0
36
297
1.23
0.52
2.1
2.9
71.81
70.78
e9/l
0.06
28
224
19
146
1.31
0.47
2.2
2.9
—
—
—
0
0
7
47
1.50
0.47
1.6
1.6
—
—
—
0
0
26
209
1.26
0.47
4.0
5.0
—
—
—
0
0
119
1094
1.12
0.46
2.8
3.1
1956.49
270.19
mg/l
1.11
83
699
34
283
1.22
0.46
2.3
2.5
4.14
4.37
kpa
0.36
34
271
26
210
1.25
0.46
1.1
1.3
—
—
—
0
0
59
667
0.87
0.44
1.8
1.7
1210.18
1240.16
nmol/l
0.11
45
495
5
31
1.62
0.43
2.2
1.1
—
—
—
0
0
64
715
0.88
0.41
2.6
2.9
2.44
2.45
mmol/l
0.29
59
633
0
17
0.00
0.40
0.0
11.5
—
0.72
—
0
17
5
34
1.48
0.40
1.0
1.1
—
—
—
0
0
13
97
1.35
0.40
1.5
1.4
291.57
316.71
ug/g
—
7
49
30
355
0.83
0.39
1.5
1.5
—
—
—
0
0
15
115
1.31
0.39
3.9
3.5
5.09
2.65
ratio
—
5
11
15
115
1.31
0.39
3.9
3.6
29.88
57.87
mg/l
0.55
15
94
15
115
1.31
0.39
3.9
3.6
71.57
108.32
mg/l
0.26
15
94
9
66
1.37
0.38
1.1
1.3
—
—
—
0
0
355
3469
1.11
0.38
5.2
5.7
39.45
39.92
mmol/mol
0.52
335
3238
9
67
1.35
0.38
1.1
1.3
—
—
—
0
0
9
67
1.35
0.38
1.1
1.3
—
—
—
0
0
25
207
1.22
0.37
1.1
1.4
—
—
—
0
0
5
37
1.36
0.37
1.0
1.0
—
—
—
0
0
12
157
0.76
0.36
1.1
1.1
—
76.57
—
0
7
359
3662
0.90
0.36
4.3
4.5
1.43
1.50
mmol/l
2.77
338
3381
9
125
0.71
0.35
1.2
1.6
—
—
—
0
0
245
2361
1.08
0.35
3.0
3.1
52.81
50.76
u/l
0.16
235
2197
103
1106
0.91
0.34
3.1
3.7
—
—
—
0
0
45
398
1.15
0.33
2.0
2.7
2.08
1.81
%
0.87
40
355
124
1164
1.09
0.33
3.1
3.6
7.32
7.24
mg/mmol
0.01
79
721
26
220
1.19
0.32
1.2
1.2
276.35
134.86
iu/ml
—
8
99
121
1138
1.09
0.31
2.7
3.0
7.09
7.35
mmol/l
0.29
116
958
71
654
1.10
0.28
1.5
1.4
2.58
2.53
g/l
0.04
40
407
25
290
0.85
0.28
4.6
3.7
—
—
—
0
0
25
290
0.85
0.28
3.6
3.5
—
—
—
0
0
53
482
1.11
0.27
1.2
1.3
—
—
—
0
0
8
66
1.22
0.27
1.1
1.3
—
—
—
0
0
6
81
0.74
0.24
1.0
1.5
—
—
—
0
0
6
82
0.73
0.24
3.2
3.7
12.25
29.29
mg/l
—
6
53
14
115
1.22
0.23
1.1
1.2
—
—
—
0
0
7
93
0.75
0.22
3.1
3.1
7.42
7.41
ph
—
7
77
7
94
0.74
0.22
3.4
2.9
1.67
1.55
mg/l
—
7
83
32
356
0.89
0.21
1.2
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
0.64
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
132
1266
1.06
0.20
2.6
3.6
2.36
2.36
mmol/l
0.04
122
1111
0
14
0.00
0.20
0.0
1.4
—
71.56
—
0
9
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
51
1.18
0.19
1.5
1.8
1.58
1.48
mmol/l
—
6
51
6
51
1.18
0.19
1.5
2.7
—
—
—
0
0
39
357
1.10
0.19
1.2
1.5
—
—
—
0
0
11
132
0.83
0.18
1.8
3.5
—
—
—
0
0
7
61
1.15
0.17
1.1
1.2
66.14
60.93
mmol/l
—
7
54
36
330
1.10
0.17
1.2
1.5
—
—
—
0
0
8
72
1.11
0.16
1.5
1.9
4.84
4.65
mmol/24h
—
8
65
31
337
0.91
0.15
2.5
4.2
—
—
—
0
0
13
150
0.86
0.15
1.3
1.2
—
—
—
0
0
43
403
1.07
0.13
2.0
2.5
113.69
133.26
ug/g
0.25
38
326
373
3760
0.95
0.12
4.9
5.0
2.71
2.79
mmol/l
1.04
352
3483
36
338
1.07
0.11
2.7
3.3
5.86
5.81
kpa
0.12
36
327
33
352
0.93
0.11
1.5
1.4
—
—
—
0
0
366
3688
0.96
0.10
4.5
4.5
4.58
4.73
mmol/l
2.21
346
3430
31
290
1.07
0.10
8.2
7.7
—
—
—
0
0
5
45
1.11
0.10
4.6
2.0
—
—
—
0
0
48
458
1.05
0.09
7.1
6.4
105.19
103.84
mmol/l
2.04
48
458
5
61
0.82
0.08
1.6
1.2
8.20
9.43
u/l
—
5
50
6
71
0.84
0.07
5.0
2.8
—
—
—
0
0
7
81
0.86
0.07
2.3
2.3
—
—
—
0
0
9
88
1.02
0.07
1.0
1.2
—
—
—
0
0
11
99
1.11
0.06
3.2
3.3
—
—
—
0
0
42
433
0.97
0.04
1.1
1.3
—
—
—
0
0
10
91
1.10
0.04
1.1
1.2
—
68.33
—
0
6
11
118
0.93
0.03
1.8
3.7
1.03
1.36
mmol/l
1.64
11
113
15
143
1.05
0.01
1.1
1.1
—
—
—
0
0
72
712
1.01
0.01
2.6
2.8
553.95
543.19
mosm/kgh2o
0.13
66
615
10
99
1.01
0.00
1.1
1.1
—
—
—
0
0
355
3554
0.99
0.00
3.9
4.0
1.37
1.29
mmol/l
1.27
335
3263
7
72
0.97
0.00
3.1
3.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
1.73
—
0
6
0
6
0.00
-0.00
0.0
2.0
—
12822.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
1727.44
—
0
9
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
16.80
—
0
7
7
75
0.93
-0.00
1.0
1.2
21.27
19.42
u/l
—
7
64
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
58
0.86
-0.00
2.6
4.1
60.60
57.97
%
—
5
58
5
56
0.89
-0.00
2.2
3.5
4.09
4.54
e9/l
—
5
56
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.6
—
—
—
0
0
5
50
1.00
-0.00
1.6
2.4
33.20
32.42
pg
—
5
50
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
16.50
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
43.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint G6_LSROOT and mortality.

Females

Parameter HR [95% CI] p-value
G6_LSROOT 1.109 [0.93, 1.32] 0.251
Birth year 0.998 [0.99, 1.01] 0.698

During the follow-up period (1.1.1998 — 31.12.2019), 198 out of 1477 females with G6_LSROOT died.

Males

Parameter HR [95% CI] p-value
G6_LSROOT 1.121 [0.94, 1.34] 0.205
Birth year 0.989 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 241 out of 1304 males with G6_LSROOT died.

Mortality risk

Mortality risk for people of age

years, who have G6_LSROOT.

N-year risk Females Males
1 0.112% 0.173%
5 0.749% 1.307%
10 1.701% 3.452%
15 3.364% 6.466%
20 6.176% 10.951%

Relationships between endpoints

↥

Index endpoint: G6_LSROOT – Lumbosacral root disorders, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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