No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
263 |
4. Check minimum number of eventsNone |
263 |
5. Include endpointsNone |
263 |
6. Filter based on genotype QC (FinnGen only) |
257 |
Control definitions (FinnGen only)
- Control exclude
- K11_INTESTOTH
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Impaction of intestines
based on the number of shared cases.
Similar with more cases:
- Paralytic ileus and intestinal obstruction
- Other diseases of intestines
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3077 | 1658 | 1372 |
| Only index persons | 1888 | 1071 | 817 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.04 |
| Only index persons | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 66.50 | 69.86 | 62.39 |
| Only index persons | 59.60 | 63.66 | 54.27 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 257 | 142 | 115 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | 60.39 | 56.94 | 64.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 263
- Matched controls
- 2630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K56.4
ICD-10 Finland
Other impaction of intestine
+∞
135.5
118
*
K56.3
ICD-10 Finland
Gallstone ileus
+∞
97.0
87
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
16.3
62.6
58
45
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
719.7
60.2
57
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.1
51.4
51
44
UJF32
NOMESCO Finland
Coloscopy
6.9
48.6
101
218
K56.7
ICD-10 Finland
Ileus, unspecified
+∞
45.1
42
*
JN3AD
NOMESCO Finland
Abdominal CT examination
8.1
39.9
62
97
K59.09
ICD-10 Finland
Constipation, unspecified
13.3
38.7
39
34
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
5.1
38.5
139
474
K59.0
ICD-10 Finland
Constipation
12.5
37.3
39
36
WX302
NOMESCO Finland
Thoracal epidural anesthesy
12.9
36.1
37
33
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
+∞
33.0
31
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.4
31.9
52
85
JFB00
NOMESCO Finland
Partial resection of small intestine
108.2
27.2
29
*
56030
ICD-8 Finland
Intestinal obstruction without mention of hernia, Impaction of intestine
+∞
23.3
22
*
JFA00
NOMESCO Finland
Enterotomy
+∞
23.3
22
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
125.5
21.9
23
*
JAH00
NOMESCO Finland
Laparotomy
20.1
21.5
32
18
A06AC01
ATC
ispaghula (psylla seeds); oral
3.7
20.6
87
310
5603C
ICD-9 Finland
Intestinal obstruction without mention of hernia, Impaction of intestine[OBSTRUCTIO INTESTINALIS,KOVETTUNUT SUOLENSISÄLTÖ]
+∞
20.0
19
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.1
18.6
26
35
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
18.1
97
397
K56.0
ICD-10 Finland
Paralytic ileus
+∞
16.8
16
*
A06AD11
ATC
lactulose; oral
3.6
16.5
66
224
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.1
16.4
30
54
ZXD05
NOMESCO Finland
Urgent procedure
2.9
15.6
111
527
UJF30
NOMESCO Finland
Ileoscopy through colon
5.6
15.0
30
59
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
60.3
15.0
17
*
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
15.6
14.3
23
16
N03AX16
ATC
[U] pregabalin
2.9
13.1
76
319
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.1
12.6
62
236
N02AX02
ATC
tramadol; systemic, rectal
2.5
12.4
130
731
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.7
11.7
41
126
UJG02
NOMESCO Finland
Proctoscopy
26.4
11.3
15
6
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.8
10.5
62
259
N02AA05
ATC
oxycodone; systemic
2.7
10.4
67
294
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
24.5
10.3
14
6
A02BC02
ATC
pantoprazole; systemic
2.5
10.3
182
1256
N06AX21
ATC
duloxetine; oral
3.4
9.8
38
124
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
9.7
78
379
N05AH04
ATC
quetiapine; oral
2.8
9.6
57
238
B01AB05
ATC
enoxaparin; parenteral
2.3
9.5
97
525
JFA70
NOMESCO Finland
Suture of small intestine
103.6
9.5
10
*
K56.2
ICD-10 Finland
Volvulus
+∞
9.4
9
*
5603X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Impaction of intestine[OBSTRUCTIO INTESTINALIS,MUU SUOLEN SISÄINEN SYY]
+∞
9.4
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
9.3
69
322
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
9.3
42
151
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
9.2
58
250
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.0
8.9
21
32
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
8.9
33
105
6421
FHL
Appendicectomy
4.3
8.7
23
57
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.7
8.6
28
81
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.7
8.6
29
86
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
28.6
8.5
11
*
45599
ICD-8 Finland
Haemorrhoids
+∞
8.4
8
*
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
+∞
8.4
8
*
P01AB01
ATC
metronidazole; oral, rectal
2.2
8.3
105
615
SPAT1255
SPAT
Intravenous administration of medicine
3.8
8.2
26
74
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
8.2
60
278
N05BA04
ATC
oxazepam; oral
2.3
8.1
80
422
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
7.0
8.0
19
29
R11
ICD-10 Finland
Nausea and vomiting
3.3
7.5
30
100
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.6
7.5
25
74
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
7.4
40
158
K62.3
ICD-10 Finland
Rectal prolapse
+∞
7.3
7
*
56096
ICD-8 Finland
Intestinal obstruction without mention of hernia, Ileus propter adhaesionem (functione laesa circulationis intestinalis non indicata)
+∞
7.3
7
*
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
+∞
7.3
7
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
6.4
7.2
18
30
A07EC02
ATC
mesalazine; oral, rectal
4.4
7.1
18
43
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
7.9
7.0
15
20
J01MA12
ATC
levofloxacin; systemic
2.4
7.0
57
276
N05CF01
ATC
zopiclone; oral
2.1
7.0
99
598
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
14.3
7.0
11
8
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
6.9
89
519
R10.0
ICD-10 Finland
Acute abdomen
9.7
6.9
13
14
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.5
6.9
17
40
K50.8
ICD-10 Finland
Other Crohn disease
17.2
6.8
10
6
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
41.1
6.8
8
*
N05BA01
ATC
diazepam; systemic, rectal
2.6
6.8
43
185
N05AA02
ATC
levomepromazine; systemic
5.8
6.7
18
33
P06
ICPC
Sleep disturbance
2.8
6.7
35
136
R15
ICD-10 Finland
Faecal incontinence
9.1
6.6
13
15
C05AA08
ATC
fluocortolone; rectal, topical
2.8
6.6
36
143
JF1AD
NOMESCO Finland
Small bowel CT
71.5
6.5
7
*
6561
FHL
Removal of fasteners and related measures
71.5
6.5
7
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
14.8
6.4
10
7
WX892
NOMESCO Finland
Monitored bed care
3.3
6.4
25
82
N06AB06
ATC
sertraline; oral
2.8
6.3
34
134
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
7.3
6.3
14
20
K50.0
ICD-10 Finland
Crohn disease of small intestine
18.6
6.3
9
5
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
18.6
6.3
9
5
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
+∞
6.3
6
*
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
+∞
6.3
6
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
6.3
51
246
N06AX03
ATC
mianserin; oral
4.0
6.2
18
48
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.3
6.2
16
39
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.6
6.1
20
58
B80
ICPC
Iron deficiency anaemia
8.9
6.1
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
115
516
3.18
18.44
4.4
2.1
59.98
55.99
u/l
0.15
110
472
62
219
3.40
14.39
8.1
6.1
104.68
104.34
mmol/l
0.22
62
219
148
929
2.36
10.49
10.4
6.4
1.21
1.21
mmol/l
0.83
134
785
90
459
2.46
10.18
2.8
2.0
3.39
3.01
mg/l
0.46
74
385
125
740
2.31
10.03
5.6
3.7
33.65
59.69
ng/l
1.39
91
528
44
156
3.19
9.96
7.6
6.0
1.43
1.36
mmol/l
0.16
44
151
146
926
2.30
9.90
21.4
15.9
1.31
1.31
inr
0.00
41
266
45
164
3.10
9.72
5.6
3.7
6.02
5.77
kpa
0.89
45
156
39
131
3.32
9.63
2.5
1.4
—
—
—
0
0
33
103
3.52
9.12
1.8
1.2
—
—
—
0
0
30
90
3.63
8.78
7.1
6.7
24.99
25.16
mmol/l
0.07
30
90
133
859
2.11
8.09
4.3
2.4
—
—
—
0
0
163
1137
2.14
8.08
8.4
4.1
6.64
6.71
mmol/l
0.17
156
1065
55
246
2.56
8.04
3.0
2.4
19.84
22.92
%
0.80
45
205
126
799
2.11
8.03
8.8
4.1
34.14
35.33
g/l
1.45
121
737
194
1452
2.28
7.99
12.9
6.5
83.49
78.16
u/l
0.52
186
1340
40
153
2.90
7.90
4.1
2.1
30.44
30.01
u/l
0.05
34
133
45
185
2.73
7.77
3.3
2.3
11.18
9.38
umol/l
0.21
40
163
44
179
2.75
7.75
4.5
3.5
4.07
45.73
ug/l
0.57
36
150
38
143
2.94
7.72
5.0
2.6
4.42
4.29
kpa
0.16
38
134
124
794
2.06
7.58
4.0
2.6
109.54
116.73
ug/l
0.23
112
714
79
426
2.22
7.55
4.4
2.1
—
—
—
0
0
59
282
2.41
7.46
5.0
2.8
0.82
0.82
mmol/l
0.07
52
261
98
581
2.09
7.32
3.1
3.1
2012.77
1410.40
ng/l
0.65
91
502
151
1048
2.04
7.29
15.0
8.7
4.27
4.11
e9/l
0.45
141
925
108
672
2.03
7.01
4.6
2.9
—
—
—
0
0
57
278
2.34
6.85
3.3
2.4
11.50
13.21
umol/l
0.97
50
255
71
380
2.19
6.84
2.3
1.7
0.79
1.15
mg/l
1.76
55
303
83
480
2.07
6.51
2.0
1.5
22.71
21.76
nmol/l
0.19
70
400
126
854
1.91
6.19
10.6
5.3
1.20
1.21
mmol/l
2.55
117
759
161
1184
1.93
6.14
5.4
2.7
43.32
44.75
u/l
0.11
153
1099
70
390
2.08
6.01
2.1
1.6
1230.88
1171.79
nmol/l
0.17
55
293
40
176
2.50
5.99
14.3
7.5
115.65
120.72
g/l
0.80
40
169
116
772
1.90
5.97
2.7
2.0
92.67
93.39
pmol/l
0.06
74
391
93
577
1.95
5.89
4.0
2.7
26.79
30.13
u/l
0.61
82
552
72
411
2.04
5.77
1.9
1.7
440.45
428.00
pmol/l
0.15
65
339
58
308
2.13
5.61
2.0
1.8
—
—
—
0
0
27
101
2.86
5.53
3.2
3.9
1.00
1.53
mmol/l
0.23
22
72
132
932
1.84
5.51
6.2
3.7
0.00
0.00
estimate
-0.00
32
185
46
224
2.28
5.50
12.8
6.4
11.67
11.95
kpa
0.16
46
212
23
79
3.09
5.45
5.3
4.1
23.80
24.08
mmol/l
0.17
23
74
133
945
1.82
5.40
6.3
3.7
0.00
0.02
estimate
0.50
30
161
63
351
2.05
5.36
1.4
1.2
0.91
1.91
u/ml
0.66
18
86
28
111
2.70
5.16
11.3
8.2
90.60
94.45
%
0.67
28
111
96
626
1.84
5.09
4.1
3.0
2.32
2.36
mmol/l
2.41
82
554
130
933
1.78
4.98
8.6
4.9
0.00
0.00
estimate
-0.00
29
164
23
85
2.87
4.82
12.3
4.6
1.71
1.54
%
0.18
23
76
15
44
3.55
4.54
2.5
2.0
134.67
126.58
g/l
0.59
15
31
175
1400
1.75
4.32
5.5
3.9
13.24
13.24
mm/h
0.00
161
1264
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
52
3.21
4.16
3.4
2.2
0.30
0.33
u/ml
—
10
25
25
106
2.50
4.05
2.0
1.6
—
—
—
0
0
52
301
1.91
3.90
3.7
2.6
4.16
1.74
e6/l
1.15
31
165
15
49
3.19
3.87
2.4
3.1
—
—
—
0
0
12
28
4.44
3.87
2.1
1.4
—
—
—
0
0
78
518
1.72
3.72
5.1
2.9
0.36
0.50
e6/l
0.40
67
395
52
309
1.85
3.59
3.7
2.4
0.97
0.93
e6/l
0.06
31
172
18
69
2.73
3.55
2.6
1.8
—
—
—
0
0
9
17
5.44
3.54
2.6
1.4
—
—
—
0
0
9
17
5.44
3.54
2.3
1.4
—
—
—
0
0
9
17
5.44
3.54
2.6
1.4
—
—
—
0
0
9
17
5.44
3.54
2.6
1.4
—
—
—
0
0
8
13
6.31
3.52
22.5
20.9
1575.75
1720.69
nmol/l
—
8
13
12
32
3.88
3.43
1.5
1.3
230.71
331.31
ug/g
—
7
16
9
18
5.14
3.40
2.3
1.4
—
—
—
0
0
9
18
5.14
3.40
2.3
1.4
—
—
—
0
0
101
732
1.62
3.39
7.0
3.9
—
—
—
0
0
16
59
2.82
3.39
2.8
1.7
—
—
—
0
0
39
216
1.95
3.32
1.6
1.7
—
—
—
0
0
73
491
1.67
3.28
6.6
4.1
0.00
0.00
estimate
-0.00
30
163
8
15
5.46
3.21
7.5
2.2
—
—
—
0
0
85
598
1.62
3.19
4.1
3.8
6.30
9.93
mg/mmol
0.49
54
375
103
762
1.58
3.13
3.7
2.2
75.55
76.36
nmol/l
0.11
91
665
11
30
3.78
3.12
4.5
3.7
5.02
5.23
kpa
0.33
11
30
9
21
4.40
3.02
1.2
1.1
—
—
—
0
0
70
475
1.65
3.02
3.6
2.4
358.41
9906.02
umol/l
2.77
63
411
5
5
10.16
2.99
6.2
1.6
29.40
37.40
umol/l
—
5
5
5
5
10.16
2.99
4.6
2.4
42162.40
28801.00
ug/l
—
5
5
173
1448
1.57
2.98
4.7
3.9
14.94
14.96
pmol/l
0.03
152
1298
59
384
1.69
2.97
4.3
3.9
1570.33
213.10
ng/l
0.70
47
304
38
221
1.84
2.80
1.7
1.7
—
—
—
0
0
7
15
4.76
2.61
3.0
1.9
—
—
—
0
0
7
16
4.46
2.49
1.1
1.0
48.43
61.31
u/l
—
7
16
134
1091
1.47
2.42
3.3
3.0
—
—
—
0
0
201
1782
1.54
2.31
5.9
4.6
1.99
1.96
mu/l
0.17
180
1599
7
18
3.96
2.26
1.1
1.0
—
—
—
0
0
8
24
3.40
2.20
6.9
4.5
—
378.80
—
0
5
212
1913
1.56
2.14
33.2
13.1
27.43
23.96
mg/l
0.71
194
1503
12
49
2.52
2.13
2.8
1.4
—
—
—
0
0
12
50
2.47
2.05
1.8
1.2
—
—
—
0
0
11
44
2.57
2.04
1.5
1.8
—
—
—
0
0
24
137
1.83
1.91
5.2
4.1
123.90
89.62
ng/l
0.61
18
119
11
47
2.40
1.80
2.6
2.6
752.33
106.32
ug/min
—
6
26
10
40
2.56
1.68
1.7
1.6
—
—
—
0
0
5
14
3.62
1.62
1.0
1.1
—
—
—
0
0
8
32
2.55
1.61
1.1
1.2
10.75
27.06
u/l
—
8
27
42
295
1.50
1.54
1.5
1.5
—
—
—
0
0
7
28
2.54
1.46
3.1
3.2
57.57
58.82
%
—
7
28
9
39
2.35
1.44
1.3
1.3
—
—
—
0
0
196
1790
1.37
1.43
27.8
12.4
78.38
78.35
ml/min/173m2
0.01
172
1465
6
23
2.64
1.37
1.2
1.1
—
—
—
0
0
5
17
2.98
1.36
1.2
1.8
12.48
14.91
ug/l
—
5
17
196
1796
1.36
1.35
7.1
5.9
39.91
40.19
mmol/mol
0.15
178
1659
26
169
1.60
1.35
2.3
2.5
13.62
8.22
ug/l
0.23
21
147
40
288
1.46
1.32
1.3
1.3
144.40
39.15
iu/ml
—
5
93
8
34
2.39
1.30
1.7
1.6
—
—
—
0
0
5
18
2.81
1.29
1.0
1.2
142.00
355.22
u/l
—
5
18
5
19
2.66
1.22
1.0
1.1
—
—
—
0
0
5
19
2.66
1.22
2.0
1.4
—
—
—
0
0
27
186
1.50
1.11
5.9
3.3
—
—
—
0
0
7
32
2.22
1.09
1.9
1.4
—
—
—
0
0
5
22
2.30
1.04
1.0
1.0
—
—
—
0
0
5
22
2.30
1.04
1.0
1.2
—
—
—
0
0
16
99
1.66
1.02
1.3
3.0
4.37
4.43
pmol/l
—
9
81
14
84
1.70
1.00
1.4
1.4
—
—
—
0
0
21
141
1.53
0.98
2.7
2.8
81.70
58.45
ml/min/173m2
—
10
51
7
37
1.92
0.94
1.3
1.1
—
—
—
0
0
32
237
1.40
0.93
5.4
4.5
32.60
32.03
%
0.09
20
156
200
1879
1.27
0.88
5.2
4.5
5.98
5.99
mmol/l
0.02
178
1697
191
1786
1.25
0.87
4.9
3.9
1.37
1.26
mmol/l
1.18
177
1622
35
268
1.35
0.85
1.4
1.3
29.95
12.85
u/ml
0.39
17
88
8
47
1.72
0.81
1.1
1.4
109.13
76.68
pmol/l
—
8
47
8
47
1.72
0.81
1.9
1.3
—
—
—
0
0
6
34
1.78
0.77
2.5
1.4
—
—
—
0
0
9
53
1.72
0.76
1.4
1.2
—
—
—
0
0
9
54
1.69
0.75
1.4
1.2
—
—
—
0
0
5
24
2.10
0.75
2.0
1.3
—
—
—
0
0
18
126
1.46
0.72
20.6
6.7
25.32
24.58
mmol/l
0.31
18
117
7
40
1.77
0.72
2.9
1.3
486.57
78.56
e6/l
—
7
34
12
78
1.56
0.66
1.3
1.4
—
—
—
0
0
5
29
1.74
0.64
2.0
1.4
—
—
—
0
0
6
36
1.68
0.57
1.2
1.4
—
9.90
—
0
5
201
1926
1.19
0.53
5.7
4.9
2.61
2.73
mmol/l
1.05
186
1756
6
40
1.51
0.52
2.0
1.5
—
—
—
0
0
6
40
1.51
0.52
1.0
1.4
—
—
—
0
0
6
40
1.51
0.52
1.0
1.4
—
—
—
0
0
6
40
1.51
0.52
3.0
1.8
—
—
—
0
0
9
126
0.70
0.44
1.4
1.7
—
—
—
0
0
29
240
1.23
0.43
8.3
7.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.7
—
13.32
—
0
18
220
2142
1.17
0.37
46.5
19.5
38.65
39.88
%
1.81
208
1985
6
42
1.44
0.36
2.5
1.4
—
—
—
0
0
192
1859
1.12
0.33
5.3
4.3
1.43
1.48
mmol/l
0.76
177
1695
6
47
1.28
0.32
1.0
1.3
—
—
—
0
0
53
484
1.12
0.27
2.3
1.6
1.45
1.32
mmol/l
0.62
43
399
5
41
1.22
0.22
2.0
1.4
—
—
—
0
0
192
1877
1.08
0.20
5.3
4.4
4.45
4.63
mmol/l
1.50
180
1726
6
49
1.23
0.20
1.3
1.8
—
—
—
0
0
9
79
1.14
0.15
1.0
1.0
—
—
—
0
0
6
57
1.05
0.08
1.5
1.5
—
—
—
0
0
9
85
1.06
0.07
1.0
1.7
—
—
—
0
0
18
167
1.08
0.07
2.1
1.9
—
—
—
0
0
48
464
1.04
0.06
3.9
4.0
18.37
22.89
%
1.11
22
206
35
336
1.05
0.05
3.0
2.9
0.60
0.95
ug/l
2.30
25
205
27
278
0.97
0.02
1.6
1.3
—
—
—
0
0
11
103
1.07
0.02
2.0
1.8
—
—
—
0
0
57
571
1.00
0.00
5.2
4.5
1.65
3.66
ug/l
1.85
49
506
19
187
1.02
0.00
2.2
2.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
8.83
—
0
9
6
60
1.00
-0.00
2.7
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.96
—
0
5
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
18.44
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.27
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
1.18
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_IMPACT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_IMPACT | 1.676 [1.35, 2.08] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.109 |
During the follow-up period (1.1.1998 — 31.12.2019), 288 out of 744 females with K11_IMPACT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_IMPACT | 2.113 [1.56, 2.85] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 212 out of 515 males with K11_IMPACT died.
Mortality risk
Mortality risk for people of age
years, who have K11_IMPACT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.154% | 0.352% |
| 5 | 0.97% | 2.227% |
| 10 | 2.367% | 5.192% |
| 15 | 4.398% | 10.302% |
| 20 | 7.868% | 16.948% |
Relationships between endpoints
↥Index endpoint: K11_IMPACT – Impaction of intestines
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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