Benign neoplasm: Choroid

CD2_BENIGN_CHOROID

choroid cancer: Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31.3&
  • Hospital discharge: ICD-9 2246
  • Cause of death: ICD-10 D31.3&
  • Cause of death: ICD-9 2246

2 out of 7 registries used, show all original rules.

2095

4. Check minimum number of events

None

2095

5. Include endpoints

None

2095

6. Filter based on genotype QC (FinnGen only)

2095

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum chorioideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11875 7347 4502
Only index persons 11506 7160 4346
Unadjusted period prevalence (%)
Whole population 0.18 0.21 0.13
Only index persons 0.23 0.26 0.17
Median age at first event (years)
Whole population 65.87 65.27 66.87
Only index persons 65.71 65.12 66.70

-FinnGen-

Key figures

All Female Male
Number of individuals 2095 1271 824
Unadjusted period prevalence (%) 0.41 0.43 0.36
Median age at first event (years) 65.29 63.15 68.58

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1836
Matched controls
18359
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
4503599627370496.0
323.0
1828
12
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
14.3
307.3
562
548
XCK10
NOMESCO Finland
Photography of fundus of eye
7.8
232.5
614
1106
XCD10
NOMESCO Finland
Electrophysiological examination of eye
20.6
221.6
341
201
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
115.3
207.5
223
22
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.5
163.4
479
941
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.0
114.9
565
1849
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.2
96.0
426
1243
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
69.0
63.8
73
11
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
71.7
43.2
49
7
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
71.7
43.2
49
7
D31.2
ICD-10 Finland
Benign neoplasm: Retina
143.2
39.9
42
*
XCD20
NOMESCO Finland
Photoangiography of eye
7.9
39.7
93
123
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
36.7
39.2
50
14
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
30.7
837
5844
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
35.6
27.5
35
10
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
21.0
286
1529
WX140
NOMESCO Finland
Parabulbar anesthesy
3.0
20.6
122
420
D31.4
ICD-10 Finland
Benign neoplasm: Ciliary body
74.3
19.7
22
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.2
18.0
202
994
ZXA10
NOMESCO Finland
Bilateral
1.8
17.5
377
2354
ZXA00
NOMESCO Finland
Right side
1.6
17.5
525
3609
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
16.0
582
4184
CH2S4
NOMESCO Finland
Photography of iris
161.3
15.5
16
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
8.5
14.5
31
37
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
151.1
14.5
15
*
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
53.7
13.8
16
*
ZXA05
NOMESCO Finland
Left side
1.6
13.7
479
3386
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
13.6
168
860
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
2.4
13.5
114
487
XCH00
NOMESCO Finland
Eye pressure measurement
2.6
13.2
97
386
CK2J4
NOMESCO Finland
Infrared imaging of ocular fundus
+∞
12.5
12
*
H31.9
ICD-10 Finland
Disorder of choroid, unspecified
130.8
12.4
13
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
12.3
478
3451
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
7.5
12.2
28
38
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.6
12.2
87
340
A98
ICPC
Health maint/preventive medicine
1.9
12.0
1724
16307
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
2.5
10.9
87
364
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
10.7
175
994
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
10.6
768
6233
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.7
10.5
219
1339
SPAT1262
SPAT
Handing over of treatment supplies
1.6
10.4
318
2162
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
40.3
10.0
12
*
H40.0
ICD-10 Finland
Glaucoma suspect
1.9
9.9
150
828
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.6
9.9
73
292
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
9.6
419
3078
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
9.4
595
4691
WX110
NOMESCO Finland
Local anesthesy
1.4
9.0
1127
9904
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.1
8.7
93
446
T90
ICPC
Diabetes non-insulin dependent
1.4
8.7
396
2928
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.3
8.6
78
350
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.8
8.5
158
934
8720/3-C69.9
ICD-O-3
Malignant melanoma, NOS, of eye, NOS
27.6
8.5
11
*
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
90.4
8.4
9
*
H26.4
ICD-10 Finland
After-cataract
1.7
8.3
169
1031
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.2
347
2524
CD2S4
NOMESCO Finland
Photography of eye
6.3
8.0
20
32
SPAT1153
SPAT
Removal of sutures
1.4
8.0
564
4501
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.0
7.8
42
142
SPAT1263
SPAT
Sampling
1.3
7.7
697
5772
CF2S4
NOMESCO Finland
Photography of conjunctiva
15.1
7.7
12
8
CKC12
NOMESCO Finland
Photocoagulation of retina
2.1
7.7
79
376
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.6
439
3380
CA1ME
NOMESCO Finland
Ultrasound oculometry
4.7
7.5
24
52
H35.7
ICD-10 Finland
Separation of retinal layers
4.7
7.5
24
52
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
7.5
109
597
H31.8
ICD-10 Finland
Other specified disorders of choroid
80.4
7.4
8
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.3
405
3098
H25.8
ICD-10 Finland
Other senile cataract
1.6
6.9
185
1214
R44
ICPC
Respiratory, Preventive immunization/medic
2.7
6.8
42
155
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
6.7
6.8
16
24
AA1AD
NOMESCO Finland
CT of head and brain
1.4
6.8
387
2967
H3600, E113
ICD-10 Finland
NA
3.3
6.7
31
94
XCK00
NOMESCO Finland
Perimetry
1.8
6.7
119
695
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
7.8
6.6
14
18
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.2
6.6
61
277
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.5
432
3394
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
6.4
876
7620
D31.1
ICD-10 Finland
Benign neoplasm: Cornea
70.1
6.4
7
*
R01AD09
ATC
mometasone; nasal
1.3
6.2
680
5739
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.3
6.2
51
221
M03BX02
ATC
tizanidine; oral
1.3
6.2
971
8588
JAETT
NOMESCO Finland
NA
5.4
6.2
17
32
S82
ICPC
Naevus/mole
1.5
6.1
180
1207
H25.0
ICD-10 Finland
Senile incipient cataract
1.7
6.1
108
633
H35.4
ICD-10 Finland
Peripheral retinal degeneration
4.2
6.0
21
51

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1827
16500
1.84
19.08
6.9
6.1
40.8
40.2
mmol/mol
2.03
1666
15148
1971
18314
2.29
18.34
19.6
17.9
139.8
139.7
mmol/l
1.05
1928
17840
1972
18353
2.27
17.83
19.7
18.1
4.0
4.0
mmol/l
0.15
1926
17854
1991
18634
2.38
17.22
12.9
11.0
25.0
25.2
u/l
0.23
1914
17938
774
5876
1.50
16.89
3.6
3.1
7.0
7.2
mmol/l
0.39
625
4915
751
5667
1.51
16.87
3.8
3.2
638.9
356.7
mg/l
0.59
461
3534
2033
19237
2.92
16.71
25.3
22.8
248.3
249.3
e9/l
0.28
1988
18721
2033
19240
2.91
16.65
25.2
22.7
91.1
91.4
fl
1.77
2003
18931
1944
18058
2.06
16.61
16.9
14.7
—
—
—
0
0
2033
19243
2.91
16.58
25.2
22.7
4.5
4.4
e12/l
0.95
1979
18670
2033
19245
2.91
16.54
25.3
22.8
6.6
6.8
e9/l
1.02
1982
18672
2033
19246
2.90
16.52
25.4
22.9
134.5
133.9
g/l
1.18
2004
18941
2032
19242
2.86
16.31
25.1
22.6
30.3
30.4
pg
0.82
2003
18930
777
5973
1.48
15.62
4.5
4.0
10.3
8.5
mg/mmol
0.42
469
3705
1983
18613
2.22
15.58
20.1
18.1
78.9
78.0
umol/l
0.53
1983
18606
956
7687
1.45
15.03
9.8
9.9
1.2
1.3
inr
0.95
280
2152
1910
17753
1.86
14.54
5.8
5.2
2.6
2.7
mmol/l
3.15
1728
16195
1050
8643
1.43
14.25
6.5
5.9
1.2
1.2
mmol/l
1.78
945
7803
1136
9487
1.43
14.22
7.1
6.7
1.2
1.2
mmol/l
0.73
918
7983
1867
17264
1.75
14.10
5.4
4.9
6.0
6.0
mmol/l
0.23
1679
15591
1887
17504
1.79
14.07
16.6
15.4
21.7
24.6
mg/l
3.74
1497
14003
1772
16222
1.60
13.25
5.5
5.0
3.3
2.0
mu/l
0.44
1591
14721
904
7374
1.40
12.25
2.4
2.2
—
—
—
0
0
1865
17378
1.67
11.93
5.1
4.6
4.6
4.6
mmol/l
2.29
1701
15950
1850
17239
1.63
11.39
5.1
4.6
1.5
1.5
mmol/l
0.34
1678
15717
630
4894
1.41
11.08
1.8
1.7
1.3
1.4
mmol/l
0.69
530
4076
486
3624
1.44
10.67
1.3
1.2
1.0
1.4
u/ml
0.97
119
948
1512
13601
1.40
10.49
4.5
4.1
14.9
14.9
pmol/l
0.00
1346
12273
1558
14101
1.41
10.32
9.0
7.7
77.0
78.8
u/l
0.89
1455
13239
1199
10410
1.35
10.27
9.3
9.1
4.0
4.1
e9/l
0.94
1071
9068
1691
15554
1.45
10.04
17.7
16.7
39.7
39.2
%
1.55
1080
10461
939
7878
1.35
9.97
2.1
2.0
98.9
94.5
pmol/l
1.55
433
3975
1354
12008
1.36
9.93
5.1
4.7
38.7
2005.4
e6/l
2.73
13
183
1434
12852
1.37
9.70
4.5
4.0
—
—
—
0
0
1389
12401
1.36
9.54
5.1
4.5
—
—
—
0
0
755
6185
1.35
9.17
6.1
5.7
—
—
—
0
0
701
5686
1.35
9.07
4.6
4.0
7.4
7.4
ph
0.57
140
1100
1470
13385
1.33
7.92
4.6
4.2
12.3
13.1
mm/h
1.29
1353
12347
1773
16668
1.41
7.43
4.5
4.1
1.3
1.3
mmol/l
0.55
1602
15072
272
1943
1.46
7.30
1.8
2.1
117.8
132.8
ug/g
0.23
208
1529
195
1300
1.55
7.30
1.2
1.2
—
—
—
0
0
107
615
1.78
7.12
4.3
6.8
1.3
1.3
mmol/l
0.01
94
533
84
450
1.90
6.99
4.3
7.6
11.3
11.2
mmol/l
0.12
75
399
84
450
1.90
6.99
4.3
7.6
105.1
105.2
mmol/l
0.08
75
399
1092
9667
1.27
6.72
7.0
6.3
11.0
11.5
umol/l
0.90
1038
9177
1545
14288
1.31
6.69
20.1
18.8
13.7
13.8
%
0.48
1511
13961
408
3225
1.33
5.92
1.5
1.5
2.3
2.5
g/l
1.40
230
1921
1193
10765
1.25
5.87
5.2
4.8
6.8
6.8
mmol/l
0.23
1136
10119
59
298
2.01
5.87
1.3
1.4
—
—
—
0
0
239
1738
1.42
5.82
3.7
3.0
195.5
206.4
ng/l
0.12
217
1586
929
8160
1.25
5.78
5.3
4.7
35.5
35.2
g/l
1.02
854
7580
1036
9217
1.25
5.73
6.2
5.9
0.2
0.2
e9/l
0.03
929
8021
672
5712
1.26
5.51
2.0
2.2
154.9
224.2
u/l
2.31
624
5351
643
5449
1.26
5.39
5.9
5.2
2.5
3.0
ug/l
0.63
564
4858
814
7106
1.24
5.19
4.1
3.8
29.3
120.2
ng/l
0.84
553
5128
210
1524
1.42
5.18
3.5
3.6
92.6
90.3
ng/l
0.11
176
1321
653
5565
1.25
5.17
4.3
4.1
—
—
—
0
0
991
8877
1.22
4.82
6.2
5.7
0.6
0.6
e9/l
0.44
881
7603
979
8759
1.22
4.82
5.2
5.2
0.0
0.0
estimate
0.50
197
1626
941
8389
1.22
4.79
6.7
6.2
8.6
8.7
%
0.50
888
7821
973
8704
1.22
4.78
4.1
3.8
0.0
0.0
estimate
0.00
189
1615
173
1232
1.44
4.74
8.3
7.0
24.4
24.5
mmol/l
0.19
162
1145
294
2292
1.33
4.65
1.3
1.3
548.2
563.2
titre
0.04
51
520
936
8357
1.22
4.64
6.4
5.9
2.9
2.8
%
0.21
878
7758
944
8439
1.22
4.61
6.3
5.8
57.2
57.6
%
0.44
887
7861
205
1514
1.39
4.59
4.4
4.1
—
—
—
0
0
992
8915
1.21
4.58
6.3
5.7
0.0
0.0
e9/l
0.45
882
7645
985
8856
1.21
4.50
4.2
3.9
0.0
0.0
estimate
1.08
190
1580
1209
11091
1.21
4.48
3.5
3.2
46.6
50.9
u/l
0.66
1113
10243
910
8128
1.21
4.43
6.4
5.9
0.7
0.7
%
0.44
855
7560
44
224
1.98
4.37
1.1
1.1
0.1
1.8
u/ml
1.93
22
84
954
8571
1.21
4.34
6.5
6.1
28.0
27.4
%
0.87
894
7945
149
1050
1.45
4.34
6.5
10.1
—
—
—
0
0
556
4734
1.24
4.32
4.8
4.2
0.0
0.0
estimate
1.08
190
1572
1007
9099
1.21
4.30
6.3
5.7
1.9
1.9
e9/l
0.09
908
7943
440
3681
1.25
3.98
4.1
3.9
458.8
367.9
ng/l
0.16
351
2969
259
2037
1.31
3.85
1.3
1.3
—
—
—
0
0
462
3915
1.23
3.69
2.0
1.8
1.0
1.3
mg/l
2.42
352
3022
295
2375
1.28
3.68
1.4
1.3
—
—
—
0
0
34
171
2.00
3.54
1.1
1.0
0.1
2.1
u/ml
—
9
39
657
5795
1.19
3.45
2.9
2.5
57.5
57.8
u/l
0.06
603
5338
144
1059
1.39
3.36
2.0
1.8
1.3
1.5
g/l
0.41
129
965
176
1337
1.35
3.35
2.8
2.8
10.3
10.6
g/l
0.51
162
1216
37
197
1.89
3.30
1.1
1.0
5.9
4.6
u/ml
0.16
23
88
214
1679
1.31
3.26
1.4
1.4
—
—
—
0
0
175
1338
1.34
3.20
1.5
1.4
—
—
—
0
0
650
5764
1.19
3.16
3.2
3.1
1758.3
1375.8
ng/l
0.61
545
4955
138
1021
1.38
3.12
2.3
2.4
—
—
—
0
0
431
3687
1.21
3.10
1.8
1.8
1252.6
1193.9
nmol/l
0.63
319
2770
660
5869
1.18
3.10
3.1
3.3
—
—
—
0
0
530
4625
1.20
3.09
3.4
3.5
—
—
—
0
0
58
361
1.62
3.06
1.7
1.4
—
—
—
0
0
142
1061
1.36
3.03
4.1
3.3
4.4
4.4
pmol/l
0.50
126
930
753
6794
1.17
2.93
3.9
3.6
—
6.0
—
0
5
24
115
2.10
2.88
2.1
1.9
553.6
718.8
e6/l
—
9
51
30
157
1.92
2.85
3.8
5.0
55.1
47.5
u/ml
—
9
42
721
6496
1.17
2.84
3.8
3.4
2.4
2.4
mmol/l
0.30
601
5638
110
799
1.40
2.81
1.3
1.2
—
—
—
0
0
35
194
1.82
2.80
1.1
1.0
0.8
1.6
u/ml
0.44
19
76
17
71
2.41
2.80
1.1
1.1
5893.5
170.7
ng/l
—
6
18
815
7441
1.16
2.65
2.9
2.8
122.6
134.6
ug/l
0.87
743
6817
28
149
1.89
2.56
1.1
1.2
—
—
—
0
0
256
2120
1.24
2.54
1.7
1.8
—
—
—
0
0
927
8568
1.15
2.49
4.2
4.1
—
—
—
0
0
20
393
0.50
2.49
4.0
3.1
7.5
7.5
mmol/l
0.06
20
383
22
417
0.52
2.45
3.8
3.0
1.4
1.6
mmol/l
1.23
22
405
12
45
2.68
2.45
1.7
1.6
—
—
—
0
0
61
408
1.51
2.43
1.5
1.2
3.9
3.9
mmol/l
0.19
55
382
6
12
5.01
2.40
5.7
3.0
—
—
—
0
0
514
4562
1.17
2.40
1.5
1.6
22.3
20.8
nmol/l
0.96
428
3844
166
1316
1.28
2.39
5.5
4.9
—
—
—
0
0
28
153
1.84
2.38
1.2
1.5
0.3
0.4
g/l
0.78
18
106
28
153
1.84
2.38
1.2
1.5
5.9
7.1
g/l
1.00
18
106
28
153
1.84
2.38
1.2
1.5
2.7
2.9
g/l
0.18
18
106
78
552
1.43
2.35
1.4
1.4
301.2
282.1
ug/g
0.34
44
329
69
477
1.46
2.35
2.5
2.0
11.7
11.8
mg/l
0.02
62
439
76
536
1.43
2.33
1.4
1.3
30.1
34.0
iu/l
0.53
70
462
236
1957
1.23
2.32
4.8
4.3
—
—
—
0
0
18
85
2.13
2.28
2.3
2.7
2284.3
1131.8
u/ml
0.41
18
85
356
3077
1.19
2.28
4.0
3.2
0.8
0.8
mmol/l
0.48
322
2876
223
1846
1.23
2.24
7.1
8.0
118.1
120.5
g/l
1.04
213
1774
463
4101
1.17
2.21
1.7
1.7
47283034.4
19940908.4
pmol/l
0.36
368
3360
25
136
1.85
2.18
1.0
1.0
0.4
4.0
u/ml
1.81
14
51
338
2923
1.19
2.16
1.3
1.2
12.0
13.0
u/ml
0.08
110
1089
48
315
1.54
2.12
1.6
1.3
10.6
12.3
u/l
0.35
40
251
21
109
1.94
2.10
5.0
6.6
—
—
—
0
0
198
1632
1.24
2.08
3.1
2.8
66.1
66.4
g/l
0.29
175
1488
262
2224
1.20
2.06
6.5
7.3
1.2
1.2
mmol/l
0.05
200
1729
0
57
0.00
2.05
0.0
2.2
—
138.5
—
0
49
20
104
1.93
2.00
1.7
1.7
—
11.1
—
0
6
104
796
1.32
1.99
3.9
5.6
1.0
0.9
%
1.27
95
740
517
4652
1.15
1.98
3.7
3.9
88.7
89.0
%
0.09
494
4536
40
257
1.57
1.95
1.3
1.6
1.3
0.9
g/l
0.30
29
192
192
1590
1.23
1.94
4.7
3.7
1.2
1.2
mmol/l
0.52
161
1389
9
33
2.73
1.93
1.3
1.0
—
—
—
0
0
27
157
1.73
1.93
1.2
1.5
—
—
—
0
0
260
2221
1.19
1.92
6.6
7.3
5.0
5.1
kpa
0.96
248
2116
260
2222
1.19
1.91
6.6
7.3
12.0
12.2
kpa
0.27
249
2117
131
1041
1.28
1.90
2.5
2.1
12.9
12.6
nmol/l
0.14
116
908
294
2543
1.18
1.88
6.3
5.3
1.1
1.0
mmol/l
0.43
261
2345
52
359
1.46
1.84
4.3
3.3
55.8
58.2
%
0.74
52
359
28
167
1.69
1.84
3.1
3.2
117.5
32.0
mg/l
0.44
22
126
572
5206
1.14
1.84
4.4
4.3
—
—
—
0
0
12
53
2.27
1.80
2.4
2.2
9.2
12.2
%
0.38
12
45
12
53
2.27
1.80
2.3
2.2
32.3
27.0
%
0.43
12
46
167
1375
1.23
1.80
2.2
2.5
—
—
—
0
0
9
35
2.58
1.80
1.2
1.5
—
—
—
0
0
103
802
1.30
1.77
4.0
5.5
1.7
1.6
%
0.66
94
746
21
118
1.79
1.70
2.2
1.9
14.0
13.5
%
0.05
12
45
84
640
1.33
1.69
1.2
1.2
2.5
0.7
u/ml
0.34
11
52
57
408
1.41
1.69
4.0
3.9
—
—
—
0
0
49
341
1.45
1.69
1.5
1.6
—
—
—
0
0
341
3013
1.16
1.68
1.3
1.3
35.4
37.7
iu/ml
0.13
103
962
431
3874
1.14
1.67
4.7
4.3
1.0
1.0
kg/l
0.20
54
585
44
301
1.47
1.66
1.7
1.5
—
—
—
0
0
34
220
1.55
1.65
1.9
1.6
—
—
—
0
0
26
158
1.65
1.62
2.5
1.9
1.8
1.1
e9/l
0.57
16
91
12
56
2.15
1.61
1.2
1.5
—
—
—
0
0
232
1996
1.18
1.61
6.9
7.7
95.4
95.5
%
0.07
222
1919
463
4192
1.13
1.60
4.4
3.8
—
—
—
0
0
49
345
1.43
1.60
3.9
3.0
3.7
4.3
e9/l
1.53
49
345
21
121
1.74
1.58
1.2
1.4
1734.0
1852.1
ml
—
5
23
21
121
1.74
1.58
2.2
1.9
74.9
71.5
%
0.56
21
111
7
26
2.70
1.58
1.1
1.1
—
—
—
0
0
38
256
1.49
1.56
1.2
1.3
0.6
0.6
nmol/l
0.46
38
244
13
64
2.04
1.54
2.7
2.6
—
—
—
0
0
415
3742
1.14
1.53
5.0
4.6
—
—
—
0
0
323
2864
1.15
1.53
2.0
2.1
29.5
29.9
s
0.75
312
2770
298
2630
1.16
1.51
1.3
1.2
—
—
—
0
0
236
2046
1.17
1.50
3.6
2.6
7.8
8.1
umol/l
0.14
207
1789
104
831
1.26
1.50
1.9
2.0
—
—
—
0
0
55
401
1.38
1.50
1.7
1.4
8.4
34.5
e6/l
1.01
45
311
55
401
1.38
1.50
1.8
1.5
344.8
1056.2
e6/l
1.00
46
329
34
499
0.68
1.48
3.7
4.5
—
—
—
0
0
236
2050
1.17
1.47
4.7
4.1
19.1
21.1
ug/l
0.07
199
1690
20
117
1.72
1.45
1.6
1.8
14.5
18.1
nmol/l
1.02
20
107
499
4570
1.12
1.43
6.8
6.7
—
—
—
0
0
539
4959
1.12
1.43
3.3
3.1
—
—
—
0
0
31
205
1.52
1.40
4.5
6.5
6.9
7.3
mmol/l
0.33
23
170
36
246
1.47
1.40
1.6
1.4
21.3
52.0
mu/l
1.70
31
219
19
111
1.72
1.39
1.3
1.5
0.9
1.0
g/l
0.89
19
111
350
3143
1.14
1.39
3.7
3.2
0.7
0.8
ug/l
0.78
239
2172
36
247
1.47
1.38
1.9
1.8
199.7
203.6
pmol/l
0.07
36
231
131
1088
1.22
1.36
1.1
1.2
74.9
142.6
iu/ml
2.73
52
403
93
745
1.26
1.34
3.1
2.6
—
—
—
0
0
77
974
0.78
1.32
3.3
3.5
—
—
—
0
0
62
472
1.32
1.31
3.0
2.9
1.7
1.6
mg/l
0.23
54
433
23
145
1.59
1.29
1.0
1.0
0.2
2.3
u/ml
2.43
11
52
33
226
1.47
1.29
1.3
1.2
—
—
nmol/l
—
0
0
26
169
1.55
1.29
1.1
1.1
—
—
—
0
0
32
218
1.48
1.28
1.3
1.2
—
—
—
0
0
325
2924
1.13
1.26
2.5
2.5
12.5
12.8
umol/l
0.22
295
2714
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
38
271
1.41
1.22
5.1
2.8
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
5
19
2.64
1.21
1.0
1.2
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
35
246
1.43
1.21
1.0
1.1
1.5
1.5
g/l
0.22
27
220
138
1168
1.19
1.20
3.5
3.7
7.4
7.4
ph
0.01
22
152
90
731
1.24
1.18
3.9
4.0
24.7
24.9
mmol/l
0.29
75
679
33
231
1.44
1.17
1.6
1.3
231.5
288.5
pmol/l
0.99
24
175
39
282
1.39
1.16
2.3
1.9
2976.4
2213.4
u/l
0.11
14
108
42
308
1.37
1.16
2.5
3.7
1.5
1.4
%
0.07
34
242
139
1183
1.19
1.15
3.5
3.7
5.1
5.2
kpa
0.18
122
1099
15
87
1.73
1.15
11.6
13.4
—
—
—
0
0
183
1595
1.16
1.14
1.5
1.5
—
—
—
0
0
239
2124
1.14
1.13
1.5
1.4
—
—
—
0
0
24
159
1.52
1.12
1.5
1.9
—
—
—
0
0
112
938
1.20
1.11
1.4
1.2
—
—
—
0
0
30
209
1.44
1.10
2.8
4.4
—
—
—
0
0
19
120
1.59
1.08
2.2
1.7
—
—
—
0
0
29
409
0.70
1.08
3.2
3.9
32.3
26.8
mg/l
0.21
21
259
189
1659
1.15
1.08
2.6
2.2
340.0
369.8
nmol/l
1.53
167
1511
1471
14325
1.09
1.05
21.9
20.2
332.3
331.7
g/l
2.19
1463
14210
31
220
1.42
1.05
2.9
2.7
—
—
—
0
0
12
67
1.80
1.04
3.8
2.0
1346.9
139.7
ug/l
0.41
12
57
151
1738
0.86
1.04
3.4
3.4
2.1
2.0
mmol/l
0.14
135
1397
33
238
1.39
1.02
1.2
1.3
—
—
—
0
0
32
230
1.40
1.01
1.3
1.2
—
—
—
0
0
27
188
1.44
1.01
2.3
3.5
68.4
55.3
%
2.45
19
125
516
4822
1.09
1.00
2.9
2.7
1945.2
6131.8
umol/l
2.70
427
4145
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
15
92
1.63
0.97
1.2
1.2
—
—
—
0
0
20
132
1.52
0.97
1.4
1.3
—
—
—
0
0
19
124
1.54
0.96
1.1
1.0
0.0
0.5
u/ml
—
5
35
54
426
1.27
0.94
4.4
4.8
2.6
2.6
mmol/l
0.01
41
301
24
166
1.45
0.94
1.0
1.0
—
—
—
0
0
6
27
2.23
0.93
2.7
2.3
17.2
17.8
umol/l
—
6
27
35
260
1.35
0.93
1.5
2.6
—
—
—
0
0
76
626
1.22
0.92
3.5
3.5
3.5
1.6
ratio
—
8
52
52
410
1.28
0.92
2.3
2.5
15.5
16.1
%
0.42
30
202
99
840
1.19
0.89
1.6
1.5
—
—
—
0
0
681
6471
1.08
0.88
4.1
3.8
77.5
116.3
e6/l
0.95
492
4644
139
1215
1.15
0.88
2.4
3.1
3.9
4.0
e9/l
0.21
109
923
60
485
1.24
0.88
4.0
3.6
—
—
—
0
0
17
111
1.54
0.87
1.5
3.1
7.4
7.4
ph
—
6
35
424
3955
1.09
0.86
2.9
2.6
5.8
5.7
e6/l
0.01
375
3472
31
230
1.35
0.85
1.6
1.6
48.0
61.3
%
1.00
20
147
14
88
1.59
0.84
1.3
1.4
—
1.4
—
0
7
8
45
1.78
0.84
1.5
2.1
—
—
—
0
0
289
2654
1.10
0.82
2.0
2.1
—
—
—
0
0
543
5129
1.08
0.82
3.4
3.2
0.3
0.5
e6/l
2.27
408
3913
53
427
1.25
0.81
1.9
1.9
3.3
4.6
iu/l
0.55
19
143
29
215
1.35
0.80
1.1
1.5
—
—
—
0
0
29
215
1.35
0.80
1.1
1.5
—
—
—
0
0
29
215
1.35
0.80
1.1
1.5
—
—
—
0
0
29
215
1.35
0.80
1.1
1.5
—
—
—
0
0
57
464
1.23
0.80
1.3
1.3
—
—
—
0
0
10
58
1.73
0.79
1.8
2.5
—
—
—
0
0
120
1047
1.16
0.79
1.2
1.2
129.6
207.3
u/ml
1.27
106
962
7
122
0.57
0.78
1.4
1.2
—
—
—
0
0
185
1665
1.12
0.77
2.2
2.7
67.6
70.0
e9/l
0.42
143
1280
28
209
1.34
0.75
1.9
2.1
—
—
—
0
0
15
99
1.52
0.75
2.7
2.9
—
—
—
0
0
7
38
1.84
0.73
12.6
7.0
—
—
—
0
0
76
644
1.19
0.73
3.5
3.5
50.8
57.4
mg/l
0.19
57
533
15
219
0.68
0.73
1.1
1.2
—
—
—
0
0
76
646
1.18
0.71
3.5
3.5
38.1
81.7
mg/l
1.17
58
536
5
26
1.93
0.70
1.0
1.2
1.5
1.8
umol/24h
—
5
26
153
1371
1.13
0.70
3.8
4.2
0.4
0.6
%
0.15
39
347
16
228
0.70
0.69
3.5
2.5
—
—
—
0
0
21
152
1.39
0.69
1.3
1.2
—
—
—
0
0
199
1813
1.11
0.69
1.5
1.6
—
—
—
0
0
24
178
1.35
0.68
1.7
1.4
—
—
—
0
0
74
865
0.85
0.68
3.1
2.4
0.6
0.6
%
0.33
74
827
5
27
1.85
0.68
1.6
1.6
—
—
—
0
0
18
127
1.42
0.68
1.2
1.2
—
—
—
0
0
98
856
1.15
0.67
3.8
3.7
—
—
—
0
0
170
1541
1.11
0.65
3.7
4.1
1.2
0.9
%
0.42
51
448
273
2534
1.09
0.65
26.9
26.4
1.3
1.4
inr
0.16
35
351
8
128
0.62
0.64
1.6
1.5
—
—
—
0
0
155
1404
1.11
0.61
3.6
3.9
0.9
0.6
%
0.87
39
320
60
509
1.18
0.60
1.0
1.1
—
—
—
0
0
31
245
1.27
0.59
2.6
2.3
603.8
1244.0
u/ml
0.22
31
237
18
131
1.38
0.59
1.2
1.2
0.5
0.6
u/ml
0.08
13
59
11
72
1.53
0.59
13.5
8.4
300.7
63.9
mg/l
—
6
52
132
1189
1.12
0.58
1.3
1.3
—
—
—
0
0
10
64
1.57
0.58
1.3
1.2
—
—
—
0
0
28
219
1.28
0.58
1.7
1.2
—
—
—
0
0
8
53
1.51
0.58
1.0
1.4
1.9
2.1
umol/l
—
8
48
26
202
1.29
0.57
1.0
1.1
—
—
—
0
0
8
55
1.46
0.56
1.1
1.8
2.1
1.4
ug/l
—
8
50
6
37
1.62
0.55
1.8
1.2
—
—
—
0
0
6
37
1.62
0.55
1.3
1.1
—
—
—
0
0
70
607
1.16
0.55
1.4
2.4
38.5
37.6
g/l
0.52
56
528
13
90
1.45
0.55
2.8
3.5
—
—
—
0
0
60
514
1.17
0.55
4.2
4.4
7.4
7.4
ph
0.04
52
421
78
889
0.87
0.55
3.1
2.5
1.2
1.2
%
0.25
78
881
8
122
0.65
0.54
1.5
1.4
—
—
—
0
0
8
123
0.65
0.54
1.5
1.4
—
—
—
0
0
26
204
1.28
0.54
1.0
1.1
—
—
—
0
0
197
1821
1.09
0.54
2.4
2.1
0.2
0.2
g/l
0.03
183
1707
42
349
1.21
0.54
2.5
2.9
—
—
—
0
0
610
5867
1.06
0.53
2.5
2.5
—
—
—
0
0
80
907
0.88
0.53
1.5
1.9
1.5
1.5
g/l
0.01
64
782
6
39
1.54
0.53
1.2
1.4
—
—
—
0
0
19
249
0.76
0.52
1.3
1.7
—
—
—
0
0
21
161
1.31
0.51
2.8
2.1
—
1.4
—
0
6
11
75
1.47
0.50
1.3
1.2
—
—
—
0
0
49
417
1.18
0.50
2.2
2.2
124.4
129.0
g/l
0.71
38
306
7
45
1.56
0.49
1.1
1.1
—
—
—
0
0
286
2697
1.07
0.48
2.5
2.5
2.3
2.3
g/l
0.30
257
2502
588
5666
1.05
0.48
3.0
3.0
—
—
—
0
0
7
46
1.52
0.48
1.1
1.0
—
—
—
0
0
53
456
1.17
0.48
1.7
1.6
8769.3
13460.4
e6/l
0.78
35
335
7
47
1.49
0.47
1.0
1.0
—
—
—
0
0
158
1457
1.09
0.47
3.8
4.1
0.1
0.1
%
0.53
47
409
31
254
1.22
0.47
1.2
1.1
—
—
—
0
0
7
48
1.46
0.46
1.0
1.2
—
—
—
0
0
183
1701
1.08
0.46
2.6
2.3
35.1
37.6
u/l
0.35
162
1468
8
121
0.66
0.45
5.5
3.3
—
—
—
0
0
26
210
1.24
0.45
1.5
2.4
—
—
—
0
0
23
183
1.26
0.45
1.5
1.3
9975.0
118278.7
e6/l
1.23
14
124
268
2531
1.07
0.44
2.5
2.6
22.8
22.4
%
0.13
206
2158
38
321
1.19
0.43
1.8
1.9
2.0
1.7
mmol/l
0.75
38
314
578
5584
1.05
0.43
3.6
3.3
193.6
76.3
e6/l
0.68
444
4333
168
1562
1.08
0.43
4.6
3.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
0.1
—
0
10
0
16
0.00
0.41
0.0
12.8
—
—
—
0
0
173
1615
1.08
0.40
1.6
1.5
—
—
—
0
0
88
796
1.11
0.40
1.8
2.0
2.7
2.1
ug/l
0.15
72
705
8
61
1.31
0.39
1.1
2.1
—
—
—
0
0
14
182
0.77
0.39
1.4
2.2
—
—
—
0
0
22
178
1.24
0.38
1.8
1.5
—
—
—
0
0
17
133
1.28
0.38
1.2
1.2
—
—
—
0
0
9
67
1.34
0.38
1.9
1.6
—
—
—
0
0
180
1689
1.07
0.38
9.7
7.1
10.8
10.0
mmol/l
0.76
170
1612
131
1214
1.08
0.38
2.6
2.4
16.3
25.7
au/ml
—
9
55
329
3147
1.05
0.37
3.0
2.7
1.0
1.3
e6/l
1.01
182
1816
35
299
1.17
0.37
1.2
1.7
—
—
—
0
0
9
69
1.31
0.37
1.0
1.0
—
10.4
—
0
7
79
871
0.90
0.37
3.4
3.6
24.3
24.1
mmol/l
0.21
73
784
308
2944
1.05
0.36
3.2
2.9
1.8
2.5
e6/l
1.50
159
1625
9
71
1.27
0.36
1.1
1.3
—
0.3
—
0
7
145
1552
0.93
0.36
6.7
8.1
—
—
—
0
0
38
438
0.87
0.35
1.1
1.2
—
—
—
0
0
12
90
1.34
0.35
1.6
1.3
134.3
141.2
nmol/l
0.21
12
90
15
117
1.28
0.35
1.4
1.1
—
—
—
0
0
379
3648
1.05
0.34
3.1
3.0
2.5
2.5
mmol/l
0.33
317
3223
11
82
1.34
0.34
3.2
3.6
—
—
—
0
0
39
340
1.15
0.33
1.8
1.6
—
—
—
0
0
15
118
1.27
0.33
1.8
2.1
499.5
492.3
min
—
6
86
6
46
1.31
0.33
1.3
1.7
—
—
—
0
0
227
2161
1.06
0.32
1.7
1.6
—
—
—
0
0
16
128
1.25
0.32
1.6
2.0
6.4
7.0
mmol/l
—
10
79
36
314
1.15
0.31
1.2
1.6
—
—
—
0
0
7
52
1.35
0.31
1.6
1.6
—
—
—
0
0
7
53
1.32
0.30
1.9
1.6
—
—
—
0
0
7
53
1.32
0.30
1.1
1.4
—
—
—
0
0
798
7821
1.03
0.29
11.3
9.8
0.0
0.0
e9/l
1.46
664
6373
47
420
1.12
0.29
1.3
1.2
—
—
—
0
0
23
194
1.19
0.29
1.2
1.4
6.8
6.6
mmol/l
0.14
23
182
10
130
0.77
0.29
1.1
1.1
—
—
—
0
0
52
468
1.11
0.29
2.5
2.4
290.9
117.5
ug/min
0.44
26
285
17
139
1.22
0.29
2.4
2.4
—
—
—
0
0
7
57
1.23
0.29
4.3
2.4
—
—
—
0
0
160
1688
0.94
0.28
2.5
2.4
6.8
6.9
ug/l
0.04
128
1489
17
205
0.83
0.28
3.9
3.2
—
—
—
0
0
490
4768
1.04
0.28
2.4
2.2
2.6
3.1
mg/l
4.67
409
4046
30
261
1.15
0.27
1.6
1.4
130.3
126.5
u/ml
—
10
50
29
252
1.15
0.27
1.2
1.1
—
—
—
0
0
68
624
1.09
0.27
1.6
1.6
—
—
—
0
0
8
66
1.21
0.26
1.3
1.1
—
—
—
0
0
14
113
1.24
0.26
1.2
1.3
—
—
—
0
0
36
319
1.13
0.26
1.1
1.7
—
—
—
0
0
8
67
1.19
0.26
2.3
2.3
—
—
—
0
0
33
373
0.88
0.26
1.3
1.3
67.9
222.7
miu/ml
—
10
159
36
320
1.13
0.25
1.2
1.7
—
—
—
0
0
380
3688
1.04
0.25
3.1
2.8
515.1
544.3
mosm/kgh2o
2.07
333
3141
43
387
1.11
0.25
1.8
1.7
263.1
311.8
mu/l
0.67
35
355
115
1217
0.94
0.23
9.8
8.7
1.3
1.3
%
0.44
115
1208
36
322
1.12
0.23
1.2
1.7
—
—
—
0
0
5
40
1.25
0.22
5.4
3.8
—
—
—
0
0
20
172
1.16
0.22
1.2
1.2
—
—
—
0
0
116
1100
1.06
0.21
1.4
1.4
—
—
—
0
0
28
248
1.13
0.21
1.1
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
7.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
15
126
1.19
0.21
2.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
4.7
—
—
—
0
0
115
1210
0.95
0.20
9.8
8.8
0.7
0.7
%
0.09
115
1201
9
112
0.80
0.20
1.6
2.3
—
—
—
0
0
48
443
1.09
0.19
2.1
1.6
—
—
—
0
0
441
4502
0.97
0.18
2.5
2.4
—
—
—
0
0
7
59
1.19
0.18
1.0
1.1
1069.3
1680.8
miu/ml
—
7
59
40
368
1.09
0.17
1.1
1.5
0.9
0.8
nmol/l
0.11
27
299
6
76
0.79
0.15
1.2
1.3
—
—
—
0
0
9
81
1.11
0.15
1.0
1.2
—
—
—
0
0
11
129
0.85
0.14
4.8
2.3
—
—
—
0
0
24
217
1.11
0.14
1.6
1.4
36603.9
115504.3
e6/l
1.05
12
123
73
767
0.95
0.14
8.8
4.4
—
—
—
0
0
33
357
0.92
0.14
1.2
1.3
59.6
60.6
mmol/l
0.06
27
288
61
644
0.95
0.14
3.1
3.1
0.4
0.3
g/l
0.26
28
251
234
2398
0.97
0.14
7.5
6.5
104.5
104.3
mmol/l
0.32
228
2336
17
191
0.89
0.14
1.1
1.2
—
—
—
0
0
12
103
1.17
0.13
1.1
1.1
—
—
—
0
0
19
170
1.12
0.13
1.2
1.1
—
—
—
0
0
16
180
0.89
0.13
1.4
1.6
—
—
—
0
0
60
569
1.06
0.13
15.7
10.3
—
—
—
0
0
12
138
0.87
0.13
1.6
1.3
—
—
—
0
0
44
413
1.07
0.13
1.8
1.5
84.7
228.0
pmol/l
2.28
44
403
113
1091
1.04
0.12
1.4
1.3
—
—
—
0
0
47
443
1.06
0.12
3.2
3.3
0.9
0.8
nmol/l
0.59
33
344
226
2210
1.03
0.12
2.1
2.6
1.8
1.8
%
0.48
193
1959
37
346
1.07
0.12
4.6
2.7
—
—
—
0
0
33
354
0.93
0.12
1.3
1.2
—
—
—
0
0
23
251
0.92
0.12
3.2
4.9
354.9
353.8
umol/l
0.01
16
218
18
162
1.11
0.11
1.4
1.4
0.3
0.3
nmol/l
—
10
117
127
1232
1.03
0.11
2.3
3.1
—
—
—
0
0
19
172
1.11
0.11
1.3
1.4
31.4
30.7
%
—
9
108
162
1662
0.97
0.11
5.9
6.7
1.4
1.4
mmol/l
0.15
154
1598
10
86
1.16
0.11
1.1
1.0
—
—
—
0
0
52
496
1.05
0.10
1.1
1.1
—
—
—
0
0
55
527
1.04
0.09
1.3
1.2
—
—
—
0
0
11
97
1.13
0.09
3.0
1.6
—
—
—
0
0
37
390
0.95
0.08
3.2
2.7
33.9
34.7
umol/l
0.06
29
326
24
224
1.07
0.08
1.3
1.2
—
—
—
0
0
8
94
0.85
0.06
2.0
1.2
240.2
364.7
u/l
—
8
85
187
1841
1.02
0.06
1.6
1.5
—
—
—
0
0
67
690
0.97
0.06
1.7
1.8
—
—
—
0
0
11
99
1.11
0.06
1.9
1.5
—
—
—
0
0
26
246
1.06
0.06
1.5
1.4
1088.6
1660.6
e6/l
1.31
19
171
16
148
1.08
0.06
1.6
1.7
9.9
11.1
%
0.52
16
148
31
296
1.05
0.06
1.5
1.4
—
—
—
0
0
29
277
1.05
0.05
1.1
1.1
142.8
76.7
iu/ml
—
6
53
17
159
1.07
0.05
1.8
2.3
895.4
624.6
ml
—
8
106
29
303
0.96
0.05
1.4
1.4
—
—
—
0
0
102
1039
0.98
0.05
1.3
1.4
—
—
—
0
0
65
666
0.98
0.05
1.7
2.3
219.8
794.1
ug/l
1.17
60
628
46
446
1.03
0.04
1.9
2.2
—
—
—
0
0
47
456
1.03
0.04
1.2
1.3
—
24.0
—
0
7
41
397
1.03
0.04
2.8
2.6
—
—
—
0
0
27
281
0.96
0.04
1.0
1.3
—
—
—
0
0
21
200
1.05
0.03
1.8
1.4
—
—
—
0
0
61
597
1.02
0.03
1.1
1.1
—
—
—
0
0
15
159
0.94
0.03
2.3
2.3
—
—
—
0
0
24
231
1.04
0.02
1.2
1.3
—
—
—
0
0
65
661
0.98
0.02
1.9
2.0
21.1
21.8
s
0.82
49
596
70
689
1.02
0.02
7.5
3.8
1.2
1.4
mmol/l
1.47
70
678
41
401
1.02
0.02
3.9
3.4
2029.4
869.6
u/ml
0.24
35
372
23
222
1.04
0.02
1.3
1.3
—
—
—
0
0
457
4585
1.00
0.02
1.4
1.3
—
—
—
0
0
10
93
1.08
0.02
1.1
1.0
—
—
—
0
0
10
107
0.93
0.02
1.0
1.6
—
—
—
0
0
13
123
1.06
0.01
1.1
1.2
9.5
11.8
mmol/l
—
7
40
12
127
0.94
0.01
1.0
1.1
28.4
33.6
mmol/l
0.52
12
113
70
709
0.99
0.01
3.8
3.4
126.6
2151.4
u/ml
0.82
58
610
57
563
1.01
0.01
3.0
3.4
—
—
—
0
0
76
767
0.99
0.01
1.6
1.5
—
—
—
0
0
10
94
1.06
0.01
1.2
2.6
—
—
—
0
0
16
154
1.04
0.00
1.1
2.0
—
—
—
0
0
10
99
1.01
0.00
1.3
1.2
—
—
—
0
0
21
205
1.02
0.00
1.8
1.4
—
—
—
0
0
24
235
1.02
0.00
1.2
1.2
2.1
5.3
u/ml
—
8
103
15
149
1.01
0.00
1.3
1.2
398.7
379.5
nmol/l
0.16
15
129
35
355
0.99
0.00
5.1
3.9
35.9
34.4
u/ml
0.03
35
350
28
276
1.01
0.00
1.3
1.2
308.8
276.6
u/ml
0.24
17
154
17
172
0.99
0.00
1.1
1.4
—
30.4
—
0
9
27
272
0.99
0.00
1.0
1.1
—
—
—
0
0
21
213
0.99
0.00
1.8
1.5
—
—
—
0
0
6
60
1.00
0.00
1.7
1.4
19.7
26.0
%
—
6
54
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
142.9
—
0
8
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
2.4
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
259.5
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
33.6
—
0
8
6
62
0.97
0.00
2.0
1.5
3.5
3.2
%
—
6
51
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
13.9
—
0
9
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CHOROID and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CHOROID 0.835 [0.74, 0.94] 0.002
Birth year 0.994 [0.98, 1.0] 0.195

During the follow-up period (1.1.1998 — 31.12.2019), 842 out of 5914 females with CD2_BENIGN_CHOROID died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_CHOROID 0.838 [0.73, 0.97] 0.016
Birth year 0.989 [0.98, 1.0] 0.023

During the follow-up period (1.1.1998 — 31.12.2019), 654 out of 3580 males with CD2_BENIGN_CHOROID died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CHOROID.

N-year risk Females Males
1 0.083% 0.147%
5 0.466% 1.013%
10 1.192% 2.645%
15 2.354% 4.999%
20 4.394% 8.679%

Relationships between endpoints

Index endpoint: CD2_BENIGN_CHOROID – Benign neoplasm: Choroid

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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