No definition available.
Other specified/unspecified nutritional deficiencies
EFO MESH Endpoint Browser PheWeb
E4_NUTRI_DEF_NAS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
268 |
4. Check minimum number of eventsNone |
268 |
5. Include endpointsNone |
268 |
6. Filter based on genotype QC (FinnGen only) |
268 |
Control definitions (FinnGen only)
- Control exclude
- E4_NUTRIDEF
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified/unspecified nutritional deficiencies
based on the number of shared cases.
Similar with more cases:
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2818 | 1684 | 1106 |
| Only index persons | 2159 | 1300 | 859 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 33.04 | 38.23 | 24.56 |
| Only index persons | 25.04 | 32.24 | 14.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 268 | 162 | 106 |
| Unadjusted period prevalence (%) | 0.05 | 0.06 | 0.05 |
| Median age at first event (years) | 26.17 | 24.50 | 28.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 248
- Matched controls
- 2478
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
26998
ICD-8 Finland
Other nutritional deficiency, Aliae definitae
+∞
207.6
169
*
26999
ICD-8 Finland
Other nutritional deficiency, Other and unspecified
+∞
43.0
40
*
K90.0
ICD-10 Finland
Coeliac disease
25.8
35.7
50
24
E63.9
ICD-10 Finland
Nutritional deficiency, unspecified
+∞
21.1
20
*
Y0599
ICD-8 Finland
Investigation of digestive system
20.6
21.0
31
17
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
114.2
19.9
21
*
E63.8
ICD-10 Finland
Other specified nutritional deficiencies
+∞
14.7
14
*
26900
ICD-8 Finland
Other nutritional deficiency, Sprue and steatorrhoea
79.6
13.7
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
11.9
93
430
26910
ICD-8 Finland
Other nutritional deficiency, Malabsorption syndrome, unspecified
51.9
8.7
10
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
82.5
7.5
8
*
78880
ICD-8 Finland
Other general symptoms, Pyrexia of unknown origin
71.6
6.5
7
*
28009
ICD-8 Finland
Iron deficiency anaemias, Unspecified
18.6
6.3
9
5
A03CA02
ATC
clidinium and psycholeptics; oral
4.3
6.3
22
55
00919
ICD-8 Finland
Diarrhoeal disease, Diarrhoea
+∞
6.3
6
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
27.4
6.3
8
*
E66.01
ICD-10 Finland
Obesity due to excess calories
13.0
6.1
10
8
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
5.8
6.1
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
88
476
2.26
8.44
2.8
1.9
2.74
3.03
mg/l
0.68
72
415
21
52
4.30
7.96
1.3
1.3
—
—
—
0
0
36
138
2.86
7.06
1.9
1.7
—
—
—
0
0
126
859
1.88
5.98
3.1
2.3
74.34
75.92
nmol/l
0.27
117
773
11
20
5.69
5.85
2.0
1.7
—
—
—
0
0
11
21
5.42
5.57
2.0
1.7
—
—
—
0
0
11
21
5.42
5.57
2.0
1.7
—
—
—
0
0
11
21
5.42
5.57
2.0
1.7
—
—
—
0
0
15
38
4.12
5.52
1.8
1.6
—
—
—
0
0
11
22
5.17
5.31
2.0
1.6
—
—
—
0
0
135
970
1.79
5.18
12.8
6.4
1.21
1.22
mmol/l
0.34
113
816
80
494
1.88
5.01
3.9
2.5
342.90
10995.52
umol/l
3.44
71
418
123
880
1.74
4.64
7.6
4.0
35.31
35.88
g/l
0.63
112
821
10
21
4.91
4.57
2.1
1.7
—
—
—
0
0
7
6
11.93
4.30
1.4
1.8
—
—
—
0
0
7
6
11.93
4.30
1.4
1.8
—
—
—
0
0
59
347
1.90
4.22
2.3
1.7
1095.55
1164.20
nmol/l
0.22
42
256
48
265
1.99
4.13
3.4
2.4
22.53
23.94
%
0.24
43
227
103
723
1.69
4.04
5.3
3.1
—
—
—
0
0
76
494
1.75
3.91
1.7
1.2
1.36
1.52
u/ml
0.10
20
141
120
889
1.63
3.75
10.0
5.5
1.22
1.22
mmol/l
0.09
111
801
61
377
1.80
3.71
5.5
3.1
1996.41
149.19
ng/l
0.74
49
284
88
605
1.68
3.67
2.6
2.0
129.39
222.27
u/l
1.51
80
572
6
6
10.19
3.51
1.5
1.8
—
—
—
0
0
6
6
10.19
3.51
1.5
1.8
—
—
—
0
0
97
693
1.63
3.45
3.4
3.1
35.25
30.48
u/l
0.59
91
670
9
18
5.13
3.40
1.1
1.2
—
—
—
0
0
41
230
1.92
3.36
29.0
23.1
1.30
1.32
inr
—
5
28
119
901
1.58
3.29
3.5
2.7
124.24
112.84
ug/l
0.24
112
841
30
155
2.05
3.09
7.8
5.8
1.26
1.35
mmol/l
0.22
30
149
150
1210
1.54
3.05
11.3
9.4
4.15
4.03
e9/l
0.28
130
1067
36
202
1.90
2.95
7.1
6.6
5.37
5.07
kpa
1.23
36
192
190
1623
1.59
2.94
11.4
7.0
84.67
74.98
u/l
1.45
180
1521
36
203
1.89
2.91
7.1
6.7
1.30
1.13
mmol/l
0.11
30
155
68
463
1.63
2.87
1.8
1.5
19.55
22.42
nmol/l
0.67
61
398
23
111
2.17
2.82
1.5
1.4
—
—
—
0
0
40
236
1.82
2.82
2.4
2.2
13.12
7.63
umol/l
0.57
32
205
161
1337
1.51
2.74
6.7
4.5
4362.20
272.21
e6/l
—
5
34
79
564
1.57
2.73
4.6
3.0
0.23
0.43
e6/l
1.19
61
413
51
336
1.64
2.44
4.2
2.6
0.45
0.88
e6/l
1.84
28
191
49
320
1.65
2.42
4.1
2.8
3.11
2.73
e6/l
0.10
25
178
9
27
3.41
2.41
1.3
1.5
—
—
—
0
0
102
788
1.48
2.39
2.6
1.9
96.21
96.12
pmol/l
0.01
62
392
125
1005
1.46
2.39
6.0
5.0
0.00
0.01
estimate
0.50
25
192
60
416
1.57
2.33
1.8
1.7
127659965.51
443.29
pmol/l
0.49
47
348
12
47
2.63
2.30
1.8
1.2
—
—
—
0
0
124
1004
1.44
2.24
4.7
3.7
0.00
0.00
estimate
0.00
25
190
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
54
2.48
2.23
3.3
2.2
0.22
0.35
u/ml
—
7
27
54
372
1.57
2.15
1.2
1.2
4.84
8.80
u/ml
0.46
15
152
33
201
1.73
2.11
4.5
3.3
—
—
—
0
0
124
1016
1.41
2.05
4.7
3.7
0.00
0.00
estimate
0.00
25
184
10
38
2.69
2.03
3.8
3.3
4.52
4.50
e9/l
—
10
38
10
38
2.69
2.03
3.8
3.8
60.80
60.50
%
—
10
38
20
106
1.96
1.97
9.2
8.8
93.67
94.38
%
0.38
20
106
180
1581
1.42
1.95
5.0
4.0
14.87
14.67
pmol/l
0.40
163
1447
89
695
1.42
1.90
3.6
3.2
2.34
2.35
mmol/l
0.37
76
611
20
108
1.92
1.87
6.2
3.4
1.11
1.82
mmol/l
0.49
15
79
228
2103
1.56
1.85
23.4
12.8
20.71
22.86
mg/l
0.54
189
1618
32
201
1.67
1.85
2.4
2.0
459.72
389.06
nmol/l
0.66
32
186
63
464
1.47
1.83
3.5
2.0
—
—
—
0
0
230
2128
1.57
1.81
26.9
14.4
3.96
3.96
mmol/l
0.10
222
2062
229
2117
1.56
1.81
26.6
14.4
139.40
139.62
mmol/l
0.65
220
2055
96
769
1.39
1.75
4.2
3.5
29.69
32.48
ng/l
0.16
59
512
15
75
2.06
1.73
1.4
1.7
20.77
4.67
ug/l
0.55
15
70
14
69
2.09
1.68
1.4
1.6
—
—
—
0
0
114
945
1.36
1.67
4.9
3.9
—
—
—
0
0
161
1415
1.35
1.57
4.1
2.9
66.93
42.97
u/l
1.35
147
1331
175
1558
1.36
1.56
5.7
3.9
12.35
11.32
mm/h
0.45
159
1435
22
131
1.74
1.55
3.8
3.0
4.25
4.57
pmol/l
1.13
22
116
26
164
1.65
1.50
8.0
7.3
117.23
122.70
g/l
0.70
26
158
7
154
0.44
1.48
1.1
1.3
—
35.10
—
0
11
69
538
1.38
1.46
3.8
2.9
1393.53
1318.54
ng/l
0.10
60
447
13
66
2.02
1.46
1.4
1.2
212.84
278.80
miu/ml
—
7
30
52
388
1.42
1.41
1.3
1.3
19.63
32.93
iu/ml
0.91
18
132
10
47
2.17
1.35
1.6
1.3
—
—
—
0
0
10
47
2.17
1.35
1.6
1.3
—
—
—
0
0
59
455
1.38
1.33
1.7
1.6
0.70
1.21
mg/l
2.38
49
349
10
49
2.08
1.23
1.3
1.3
—
—
—
0
0
11
199
0.53
1.23
1.5
1.7
—
—
—
0
0
204
1892
1.33
1.17
6.0
4.7
1.85
1.86
mu/l
0.01
186
1738
18
111
1.67
1.15
10.1
8.4
0.90
0.73
%
0.54
18
111
18
112
1.65
1.12
9.6
8.2
1.79
1.52
%
0.17
18
112
12
67
1.83
1.06
4.5
2.4
1.80
1.43
mg/l
0.61
12
58
67
547
1.30
1.04
5.7
4.0
0.00
0.01
estimate
0.50
22
186
9
47
1.95
1.03
1.6
1.9
—
—
—
0
0
69
567
1.29
1.02
5.6
4.0
9.61
6.56
mg/mmol
0.34
39
351
22
148
1.53
1.01
2.5
3.1
77.86
65.42
ml/min/173m2
—
7
69
5
23
2.20
0.98
3.0
2.5
—
—
—
0
0
50
395
1.33
0.98
3.4
2.8
2.44
2.45
mmol/l
0.37
38
345
234
2232
1.38
0.97
15.1
9.6
26.89
25.71
u/l
0.49
224
2156
8
42
1.93
0.89
1.1
1.3
—
—
—
0
0
209
1976
1.26
0.83
22.2
12.2
81.53
82.48
ml/min/173m2
0.23
179
1623
205
1936
1.25
0.81
24.7
13.5
38.30
40.24
%
1.83
149
1466
0
26
0.00
0.79
0.0
1.2
—
8.65
—
0
16
16
107
1.53
0.78
2.8
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.5
—
—
—
0
0
29
221
1.35
0.73
4.5
4.3
31.25
33.28
%
0.29
20
145
90
791
1.21
0.73
4.9
3.8
—
—
—
0
0
7
42
1.68
0.69
1.4
1.2
—
—
—
0
0
198
1878
1.21
0.66
6.8
5.4
40.46
39.47
mmol/mol
0.68
180
1761
24
311
0.75
0.64
2.4
2.8
0.55
0.85
ug/l
1.63
14
199
5
29
1.74
0.64
1.2
1.1
—
—
—
0
0
27
209
1.32
0.63
1.7
1.7
—
—
—
0
0
241
2339
1.30
0.60
33.5
19.2
252.73
249.69
e9/l
0.26
234
2281
11
72
1.55
0.60
2.5
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
1.6
—
—
—
0
0
241
2341
1.29
0.58
33.6
19.2
4.40
4.49
e12/l
2.11
233
2275
12
81
1.50
0.58
7.8
3.2
25.13
24.81
mmol/l
0.17
12
81
205
1960
1.20
0.58
4.4
3.8
1.34
1.24
mmol/l
0.72
189
1812
241
2342
1.29
0.57
33.8
19.3
132.30
135.36
g/l
2.64
236
2305
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
11
74
1.51
0.54
3.6
2.1
—
—
—
0
0
217
2090
1.20
0.53
5.2
4.7
2.74
2.81
mmol/l
0.43
199
1937
37
308
1.23
0.51
2.5
1.8
—
—
—
0
0
35
417
0.82
0.49
3.5
4.3
20.09
21.87
%
0.31
12
194
29
237
1.25
0.48
1.8
1.9
—
—
—
0
0
26
210
1.26
0.47
2.0
1.6
—
—
—
0
0
205
1978
1.15
0.42
5.2
4.2
5.94
5.87
mmol/l
0.21
186
1823
8
57
1.42
0.42
1.1
3.4
—
3.18
—
0
7
0
15
0.00
0.41
0.0
1.0
—
527.80
—
0
10
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
35.00
—
0
10
8
59
1.37
0.41
1.4
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
18
225
0.79
0.39
9.0
7.3
—
—
—
0
0
229
2232
1.18
0.39
26.8
14.8
82.19
75.85
umol/l
0.99
229
2232
26
216
1.23
0.38
2.0
1.7
—
—
—
0
0
7
53
1.33
0.31
1.6
1.8
—
—
—
0
0
11
84
1.32
0.30
2.7
3.5
63.96
49.91
%
0.87
11
84
28
243
1.17
0.28
2.8
1.7
2.00
1.48
%
1.12
21
222
9
72
1.26
0.26
1.4
1.1
—
—
—
0
0
9
73
1.24
0.25
1.4
1.1
—
—
—
0
0
6
81
0.73
0.24
1.2
1.4
—
—
—
0
0
5
39
1.29
0.23
1.2
1.2
154.00
240.26
u/ml
—
5
25
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
535.14
430.95
mg/l
—
7
55
7
61
1.15
0.17
1.9
2.3
—
—
—
0
0
5
68
0.73
0.17
1.2
1.1
—
—
—
0
0
49
522
0.92
0.16
3.7
4.6
1.78
2.84
ug/l
0.87
40
470
208
2047
1.07
0.15
4.7
4.2
1.46
1.49
mmol/l
0.35
191
1902
7
86
0.81
0.15
1.1
1.7
—
—
—
0
0
8
100
0.79
0.14
2.1
2.3
42.38
43.94
u/l
—
8
93
208
2053
1.06
0.12
4.9
4.2
4.69
4.71
mmol/l
0.11
192
1912
42
400
1.06
0.09
1.4
1.6
—
—
—
0
0
6
54
1.11
0.09
1.0
1.2
5.60
3.75
mmol/l
—
6
47
6
55
1.09
0.09
1.0
1.1
1.17
3.00
e6/l
—
6
43
6
55
1.09
0.09
1.2
1.3
22.00
200.67
e6/l
—
6
45
6
57
1.05
0.08
3.7
1.7
—
—
—
0
0
5
64
0.78
0.08
2.2
1.3
—
—
—
0
0
7
64
1.10
0.08
1.0
1.1
—
8.84
—
0
12
7
67
1.05
0.08
1.6
1.3
—
—
—
0
0
8
74
1.08
0.07
1.0
1.9
—
—
—
0
0
13
121
1.08
0.04
1.4
1.3
—
—
—
0
0
142
1407
1.02
0.03
3.6
3.2
—
—
—
0
0
11
108
1.02
0.00
1.4
1.8
—
—
—
0
0
36
361
1.00
0.00
1.4
1.5
—
—
—
0
0
54
541
1.00
0.00
1.8
1.7
1.51
1.34
mmol/l
0.44
44
456
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
11
110
1.00
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
29.40
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
7
70
1.00
0.00
1.3
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
8
81
0.99
0.00
2.4
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_NUTRI_DEF_NAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_NUTRI_DEF_NAS | 3.366 [2.28, 4.96] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.064 |
During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 230 females with E4_NUTRI_DEF_NAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_NUTRI_DEF_NAS | 4.555 [2.46, 8.43] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 157 males with E4_NUTRI_DEF_NAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_NUTRI_DEF_NAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.247% | 0.866% |
| 5 | 1.609% | 5.4% |
| 10 | 4.136% | 12.203% |
| 15 | 8.068% | 22.754% |
| 20 | 14.903% | 35.897% |
Relationships between endpoints
↥Index endpoint: E4_NUTRI_DEF_NAS – Other specified/unspecified nutritional deficiencies
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
-
8 (0.05)
-
0.02 [-0.19, 0.23]
3
0
-
40 (0.07)
-
-
-
-
-
0 (0.00)
-
0.15 [-0.29, 0.59]
-
-
-
0 (0.00)
-
0.44 [-0.29, 1.18]
1
0
-
7 (0.07)
-
0.09 [-0.20, 0.38]
9
0
-
7 (0.10)
-
-0.12 [-0.39, 0.15]
22
0
-
-
-
-0.20 [-0.72, 0.32]
2
0
-
0 (0.00)
-
-0.32 [-0.87, 0.23]
1
0
-
-
-
-
-
-
-
0 (0.00)
-
-0.52 [-1.61, 0.57]
1
-
-
0 (0.00)
-
0.14 [-0.28, 0.56]
1
0
-
0 (0.00)
-
-1.00 [-2.65, 0.65]
3
0
-
0 (0.00)
-
0.09 [-0.39, 0.57]
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-0.06 [-0.44, 0.32]
13
0
-
81 (0.06)
-
-
-
-
-
0 (0.00)
-
-0.07 [-0.37, 0.24]
-
-
-
0 (0.00)
-
-
-
-
-
27 (0.08)
-
-
-
-
-
-
-
-0.29 [-1.22, 0.64]
-
-
-
-
-
0.05 [-0.52, 0.63]
1
0
-
-
-
0.39 [-0.34, 1.12]
-
-
-
0 (0.00)
-
-0.20 [-0.59, 0.20]
2
0
-
5 (0.02)
-
-0.06 [-0.27, 0.15]
116
0
-
0 (0.00)
-
0.15 [-0.88, 1.18]
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
0.05 [-0.43, 0.52]
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.17 [-0.72, 0.37]
-
-
-
-
-
-0.08 [-0.41, 0.25]
-
-
-
0 (0.00)
-
-0.15 [-0.50, 0.20]
-
-
-
0 (0.00)
-
-0.67 [-1.79, 0.45]
1
-
-
0 (0.00)
-
-0.21 [-0.70, 0.28]
3
0
-
19 (0.08)
-
-
-
-
-
0 (0.00)
-
0.09 [-0.23, 0.41]
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.29 [-0.55, 1.12]
1
0
-
19 (0.08)
-
-0.15 [-0.34, 0.03]
90
0
-
-
-
0.36 [-0.09, 0.81]
-
-
-
-
-
0.02 [-0.56, 0.59]
2
0
-
-
-
-
-
-
-
0 (0.00)
-
0.13 [-0.27, 0.54]
1
-
-
-
-
-
-
-
-
0 (0.00)
-
0.70 [-0.97, 2.37]
3
0
-
0 (0.00)
-
0.34 [-0.47, 1.15]
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.40 [-1.04, 0.24]
-
-
-
0 (0.00)
-
-
-
-
-
60 (0.07)
-
-
-
-
-
82 (0.13)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
27 (0.09)
-
-
-
-
-
0 (0.00)
-
0.03 [-0.38, 0.43]
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-0.15 [-0.79, 0.48]
3
0
-
6 (0.10)
-
-
-
-
-
0 (0.00)
-
-0.27 [-0.69, 0.15]
-
-
-
0 (0.00)
-
-0.22 [-0.74, 0.30]
2
0
-
-
-
0.34 [-0.25, 0.93]
1
0
-
0 (0.00)
-
0.12 [-0.33, 0.57]
1
0
-
7 (0.11)
-
-0.01 [-0.29, 0.27]
25
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.03 [-0.67, 0.60]
8
0
-
-
-
-0.00 [-0.30, 0.29]
23
-
-
-
-0.15 [-0.43, 0.14]
-
-
-
-
-
0.15 [-0.11, 0.41]
29
0
-
-
-
-0.51 [-1.81, 0.78]
1
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.03 [-0.50, 0.44]
-
-
-
-
-
0.10 [-0.21, 0.41]
12
0
-
0 (0.00)
-
0.33 [-1.53, 2.18]
-
-
-
-
-
-0.55 [-1.21, 0.11]
1
0
-
14 (0.07)
-
-
-
-
-
0 (0.00)
-
-0.06 [-0.47, 0.36]
1
0
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
-
-
-
-
-
-
-
-
-
0.19 [-0.42, 0.79]
1
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.16 [-0.24, 0.56]
-
-
-
0 (0.00)
-
-
-
-
-
-
-
0.24 [-0.35, 0.83]
4
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.42 [-0.81, -0.02]
-
-
-
0 (0.00)
-
-
-
-
-
51 (0.08)
-
-
-
-
-
-
-
-0.05 [-0.29, 0.18]
73
0
-
0 (0.00)
-
0.04 [-0.54, 0.62]
-
-
-
-
-
0.10 [-0.34, 0.54]
1
0
-
0 (0.00)
-
-0.31 [-0.71, 0.10]
-
-
-
14 (0.09)
-
-0.04 [-0.24, 0.15]
66
0
-
111 (0.07)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
0.01 [-0.32, 0.34]
-
-
-
6 (0.11)
-
-0.06 [-0.65, 0.53]
10
0
-
0 (0.00)
-
-0.09 [-0.61, 0.42]
-
-
-
-
-
0.63 [-0.09, 1.36]
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
Neuroendocrine tumor and carcinoma of rectum, excluding all cancers (controls excluding all cancers)
-
0 (0.00)
-
-0.31 [-0.69, 0.07]
-
-
-
-
-
0.02 [-0.37, 0.41]
13
0
-
0 (0.00)
-
0.15 [-0.55, 0.84]
1
0
-
-
-
-0.14 [-0.56, 0.27]
10
0
-
0 (0.00)
-
0.18 [-0.13, 0.50]
-
-
-
0 (0.00)
-
0.16 [-0.35, 0.68]
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-0.17 [-0.82, 0.48]
1
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.03 [-0.39, 0.33]
-
-
-
0 (0.00)
-
0.34 [-0.08, 0.75]
-
-
-
0 (0.00)
-
-
-
-
-
60 (0.08)
-
-
-
-
-
0 (0.00)
-
0.20 [-0.39, 0.80]
1
0
-
0 (0.00)
-
-0.36 [-1.07, 0.34]
-
-
-
0 (0.00)
-
0.26 [-0.95, 1.48]
-
-
-
-
-
0.38 [-0.17, 0.92]
4
0
-
0 (0.00)
-
0.53 [-0.27, 1.33]
1
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
0.23 [-0.18, 0.64]
5
0
-
-
-
0.34 [-0.17, 0.85]
9
0
-
24 (0.09)
-
-0.07 [-0.29, 0.14]
100
0
-
-
-
0.04 [-0.30, 0.38]
-
-
-
-
-
-0.12 [-0.38, 0.15]
18
0
-
-
-
0.02 [-0.51, 0.55]
-
-
-
0 (0.00)
-
-0.05 [-0.51, 0.41]
-
-
-
-
-
0.51 [0.08, 0.93]
2
0
-
0 (0.00)
-
0.01 [-0.39, 0.42]
-
-
-
0 (0.00)
-
0.21 [-0.15, 0.57]
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-0.05 [-0.35, 0.25]
-
-
-
-
-
-0.34 [-0.62, -0.05]
-
-
-
0 (0.00)
-
-0.04 [-0.45, 0.37]
2
0
-
5 (0.05)
-
-
-
-
-
0 (0.00)
-
0.37 [-0.10, 0.85]
-
-
-
0 (0.00)
-
-1.00 [-5.00, 3.00]
-
-
-
-
-
-0.06 [-0.58, 0.46]
1
0
-
0 (0.00)
-
-0.12 [-0.47, 0.23]
-
-
-
-
-
-
-
-
-
-
-
0.03 [-0.27, 0.34]
2
0
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
0.69 [-0.37, 1.75]
3
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.02 [-0.46, 0.41]
-
-
-
51 (0.06)
-
0.12 [-0.02, 0.26]
344
0
-
7 (0.09)
-
-
-
-
-
0 (0.00)
-
-0.16 [-0.65, 0.33]
1
0
-
0 (0.00)
-
0.34 [-0.29, 0.97]
-
-
-
-
-
0.20 [-0.48, 0.88]
2
0
-
0 (0.00)
-
0.14 [-0.39, 0.66]
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.22 [-0.53, 0.08]
-
-
-
-
-
0.44 [-0.03, 0.91]
1
0
-
7 (0.06)
-
-
-
-
-
0 (0.00)
-
-0.17 [-0.59, 0.25]
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.02 [-0.26, 0.30]
-
-
-
16 (0.05)
-
-
-
-
-
-
-
-
-
-
-
-
-
-0.19 [-0.69, 0.32]
1
0
-
0 (0.00)
-
-
-
-
-
-
-
0.06 [-0.60, 0.72]
3
0
-
-
-
-0.00 [-0.52, 0.51]
1
0
-
-
-
0.43 [-0.40, 1.27]
1
-
-
0 (0.00)
-
-0.09 [-0.43, 0.25]
-
-
-
6 (0.09)
-
0.11 [-0.24, 0.47]
7
0
-
6 (0.15)
-
-
-
-
-
0 (0.00)
-
0.12 [-0.53, 0.77]
2
0
-
0 (0.00)
-
-0.04 [-0.65, 0.57]
1
0
-
-
-
0.62 [0.01, 1.22]
-
-
-
-
-
0.65 [-0.08, 1.37]
-
-
-
39 (0.06)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.24 [-0.67, 0.18]
-
-
-
0 (0.00)
-
-0.27 [-0.82, 0.28]
-
-
-
0 (0.00)
-
-
-
-
-
-
-
0.02 [-0.30, 0.35]
17
0
-
29 (0.08)
-
-0.05 [-0.27, 0.17]
105
0
-
-
-
0.03 [-0.31, 0.37]
11
0
-
0 (0.00)
-
0.25 [-0.21, 0.71]
-
-
-
0 (0.00)
-
-
-
-
-
5 (0.05)
-
-0.35 [-0.67, -0.03]
18
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.21 [-0.18, 0.59]
-
-
-
-
-
0.01 [-0.48, 0.49]
-
-
-
0 (0.00)
-
-0.07 [-0.50, 0.36]
6
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.22 [-0.68, 0.24]
-
-
-
0 (0.00)
-
-
-
-
-
-
-
0.25 [-0.13, 0.63]
12
0
-
0 (0.00)
-
0.11 [-0.23, 0.46]
-
-
Mucinous and mucinous cystic tumor of rectum, excluding all cancers (controls excluding all cancers)
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.14 [-0.36, 0.64]
1
0
-
0 (0.00)
-
-0.09 [-0.45, 0.27]
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-0.20 [-0.73, 0.34]
2
0
-
0 (0.00)
-
-0.27 [-0.69, 0.15]
-
-
-
0 (0.00)
-
0.15 [-0.56, 0.87]
1
-
-
-
-
-
-
-
-
-
-
0.19 [-0.38, 0.76]
3
0
-
-
-
0.07 [-0.18, 0.33]
26
-
0 (0.00)
-
-0.20 [-0.61, 0.20]
1
0
-
-
-
-
-
-
-
-
-
-0.12 [-0.49, 0.25]
1
-
-
0 (0.00)
-
-0.15 [-0.74, 0.44]
-
-
-
0 (0.00)
-
-0.03 [-0.38, 0.31]
-
-
-
0 (0.00)
-
-0.08 [-0.79, 0.63]
-
-
-
24 (0.07)
-
-
-
-
-
-
-
0.16 [-0.27, 0.58]
3
0
-
-
-
-0.11 [-0.39, 0.16]
16
0
-
5 (0.02)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.11 [-0.70, 0.93]
1
0
-
13 (0.06)
-
-
-
-
-
9 (0.06)
-
-
-
-
-
0 (0.00)
-
0.32 [-0.02, 0.66]
1
-
-
0 (0.00)
-
0.40 [-0.04, 0.84]
1
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.19 [-0.19, 0.58]
1
0
-
228 (0.06)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
0.31 [-0.20, 0.82]
10
0
-
-
-
-0.37 [-0.86, 0.12]
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.12 [-0.45, 0.69]
1
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.09 [-0.58, 0.40]
3
0
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.41 [-0.30, 1.11]
-
-
-
0 (0.00)
-
0.05 [-0.58, 0.67]
1
0
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-0.19 [-0.54, 0.15]
3
0
-
12 (0.05)
-
-
-
-
-
-
-
-0.07 [-0.57, 0.42]
4
0
-
0 (0.00)
-
-0.23 [-0.74, 0.27]
1
-
-
0 (0.00)
-
-0.25 [-0.75, 0.24]
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
0.02 [-0.34, 0.39]
1
0
-
-
-
-
-
-
-
-
-
-0.07 [-0.36, 0.22]
-
-
-
0 (0.00)
-
-0.42 [-1.02, 0.18]
-
-
-
-
-
0.42 [-0.03, 0.87]
1
0
-
0 (0.00)
-
-0.28 [-0.63, 0.08]
-
-
-
-
-
-
-
-
-
0 (0.00)
-
0.05 [-0.44, 0.53]
-
-
-
0 (0.00)
-
0.23 [-0.17, 0.63]
-
-
-
54 (0.07)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
0.62 [0.09, 1.15]
1
-
-
24 (0.09)
-
-0.07 [-0.28, 0.15]
102
0
-
-
-
-0.02 [-0.50, 0.46]
2
0
-
9 (0.06)
-
-
-
-
-
-
-
0.62 [-0.05, 1.29]
2
0
-
0 (0.00)
-
-0.01 [-0.30, 0.28]
-
-
-
0 (0.00)
-
0.02 [-0.37, 0.41]
2
0
Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-0.26 [-0.68, 0.16]
-
-
-
0 (0.00)
-
0.03 [-0.28, 0.34]
-
-
-
22 (0.07)
-
-0.05 [-0.28, 0.17]
86
0
-
-
-
-
-
-
-
-
-
0.05 [-0.20, 0.31]
-
-
-
0 (0.00)
-
0.21 [-0.16, 0.57]
-
-
-
0 (0.00)
-
0.14 [-0.30, 0.58]
1
0
-
0 (0.00)
-
-0.16 [-0.66, 0.35]
-
-
-
-
-
0.02 [-0.27, 0.31]
14
0
-
0 (0.00)
-
-
-
-
5 (0.11)
-
-
0.24 [-0.21, 0.69]
-
-
5 (0.13)
0 (0.00)
-
0.15 [-0.19, 0.49]
-
-
8 (0.17)
-
-
0.26 [-0.27, 0.79]
-
-
5 (0.09)
-
-
0.14 [-0.26, 0.55]
1
0
5 (0.10)
0 (0.00)
-
0.03 [-0.48, 0.54]
-
-
5 (0.08)
-
-
-0.14 [-0.67, 0.38]
-
-
5 (0.07)
0 (0.00)
-
-0.09 [-0.68, 0.50]
-
-
5 (0.06)
0 (0.00)
-
-0.06 [-0.67, 0.55]
1
0
13 (0.15)
-
-
0.10 [-0.69, 0.88]
2
0
24 (0.24)
5 (0.35)
-
-0.22 [-1.75, 1.31]
-
-
12 (0.12)
-
-
0.08 [-0.57, 0.73]
-
-
6 (0.05)
-
-
0.02 [-0.79, 0.82]
1
0
17 (0.14)
-
-
0.41 [-0.36, 1.17]
-
-
12 (0.09)
0 (0.00)
-
-0.22 [-0.77, 0.34]
-
-
12 (0.09)
-
-
-0.58 [-1.29, 0.14]
1
-
9 (0.05)
-
-
0.13 [-0.25, 0.51]
1
0
12 (0.07)
-
-
0.55 [-0.10, 1.19]
1
0
16 (0.09)
-
-
-0.29 [-0.89, 0.32]
1
-
17 (0.10)
-
-
0.16 [-0.69, 1.00]
1
-
19 (0.10)
0 (0.00)
-
-0.17 [-0.82, 0.48]
-
-
14 (0.07)
-
-
0.16 [-0.29, 0.60]
-
-
15 (0.08)
-
-
-0.86 [-2.90, 1.18]
14
0
14 (0.06)
6 (0.17)
-
0.04 [-0.25, 0.32]
7
0
37 (0.15)
10 (0.12)
-
0.17 [-0.26, 0.60]
-
-
18 (0.06)
5 (0.09)
-
-0.19 [-0.65, 0.28]
5
0
13 (0.04)
-
-
-0.21 [-0.62, 0.19]
2
0
10 (0.03)
0 (0.00)
-
0.20 [-0.20, 0.61]
-
-
12 (0.04)
-
-
0.37 [-0.24, 0.98]
1
0
47 (0.13)
-
-
0.24 [-0.72, 1.20]
-
-
33 (0.09)
-
-
-0.14 [-0.55, 0.26]
1
0
49 (0.11)
10 (0.13)
-
0.03 [-0.18, 0.25]
53
0
41 (0.09)
6 (0.10)
-
-0.01 [-0.40, 0.38]
2
0
80 (0.15)
-
-
-0.25 [-0.63, 0.13]
2
0
23 (0.04)
-
-
0.62 [-0.01, 1.26]
-
-
15 (0.03)
0 (0.00)
-
0.41 [-0.07, 0.89]
2
0
25 (0.04)
7 (0.08)
-
0.25 [-0.42, 0.92]
-
-
30 (0.04)
-
-
0.27 [-0.04, 0.58]
4
0
145 (0.20)
18 (0.25)
-
0.29 [-0.17, 0.75]
1
0
90 (0.11)
10 (0.11)
-
-0.19 [-0.46, 0.09]
23
0
33 (0.04)
8 (0.11)
-
-0.05 [-0.58, 0.48]
6
0
47 (0.05)
8 (0.06)
-
0.06 [-0.28, 0.39]
3
0
43 (0.04)
6 (0.05)
-
0.01 [-0.32, 0.34]
1
0
116 (0.12)
10 (0.08)
-
-0.09 [-0.35, 0.16]
7
0
64 (0.06)
15 (0.11)
-
0.12 [-0.25, 0.49]
2
0
50 (0.05)
14 (0.09)
-
-0.12 [-0.57, 0.33]
1
0
59 (0.05)
15 (0.09)
-
0.32 [-0.16, 0.80]
1
-
68 (0.05)
16 (0.08)
-
0.14 [-0.20, 0.47]
3
0
137 (0.10)
15 (0.09)
-
0.13 [-0.27, 0.53]
1
-
132 (0.08)
16 (0.08)
-
0.27 [-0.06, 0.59]
4
0
150 (0.09)
25 (0.08)
-
0.19 [-0.05, 0.42]
33
0
127 (0.07)
19 (0.09)
-
0.07 [-0.80, 0.93]
1
-
223 (0.11)
17 (0.08)
-
0.12 [-0.11, 0.35]
29
0
136 (0.05)
14 (0.06)
-
-0.08 [-0.47, 0.31]
1
0
282 (0.10)
27 (0.09)
-
0.12 [-0.07, 0.31]
38
0
187 (0.05)
36 (0.06)
-
0.05 [-0.11, 0.21]
57
0
304 (0.08)
49 (0.08)
-
0.22 [0.02, 0.41]
81
0
515 (0.11)
50 (0.12)
-
0.31 [0.01, 0.61]
3
0
381 (0.05)
44 (0.08)
-
-0.12 [-0.38, 0.14]
4
0
1484 (0.06)
174 (0.06)
-
0.11 [-0.03, 0.25]
314
11 (0.18)
-
-
-0.48 [-0.94, -0.01]
-
-
7 (0.10)
0 (0.00)
-
-
-
-
7 (0.09)
-
-
0.37 [-0.16, 0.89]
1
0
9 (0.10)
-
-
0.33 [-0.19, 0.84]
-
-
5 (0.05)
0 (0.00)
-
0.18 [-0.31, 0.67]
1
0
14 (0.11)
-
-
-0.10 [-0.91, 0.70]
1
-
10 (0.07)
0 (0.00)
-
0.19 [-0.38, 0.76]
1
0
5 (0.04)
0 (0.00)
-
-0.59 [-4.16, 2.98]
1
0
6 (0.04)
0 (0.00)
-
-
1
0
18 (0.11)
-
-
0.49 [-0.06, 1.03]
2
0
10 (0.06)
-
-
-0.78 [-2.41, 0.85]
-
-
7 (0.04)
-
-
0.19 [-0.39, 0.76]
-
-
13 (0.07)
-
-
-0.27 [-0.79, 0.24]
3
0
8 (0.04)
-
-
-0.49 [-1.56, 0.58]
1
0
22 (0.10)
8 (0.24)
-
0.24 [-0.24, 0.71]
1
-
36 (0.13)
10 (0.18)
-
0.30 [-0.19, 0.78]
7
0
9 (0.03)
-
-
-0.16 [-0.44, 0.12]
14
0
21 (0.07)
-
-
0.09 [-0.36, 0.53]
2
0
45 (0.14)
10 (0.27)
-
0.46 [0.09, 0.82]
1
0
18 (0.05)
-
-
-0.20 [-0.56, 0.15]
4
0
30 (0.08)
-
-
0.18 [-0.28, 0.64]
-
-
9 (0.02)
0 (0.00)
-
0.24 [-0.40, 0.88]
2
0
45 (0.11)
-
-
-0.11 [-0.67, 0.46]
3
0
42 (0.10)
10 (0.13)
-
0.34 [-0.20, 0.88]
-
-
32 (0.07)
-
-
0.14 [-0.24, 0.53]
2
0
36 (0.08)
13 (0.15)
-
0.43 [0.07, 0.79]
1
0
47 (0.10)
8 (0.13)
-
0.29 [-0.16, 0.74]
1
0
37 (0.07)
10 (0.11)
-
0.09 [-0.13, 0.30]
15
0
64 (0.11)
-
-
-0.29 [-0.92, 0.35]
1
0
57 (0.09)
9 (0.08)
-
0.07 [-0.19, 0.34]
4
0
62 (0.09)
13 (0.15)
-
0.41 [-0.27, 1.08]
10
0
33 (0.05)
7 (0.08)
-
0.02 [-0.35, 0.38]
1
0
40 (0.05)
5 (0.04)
-
0.02 [-0.51, 0.54]
-
-
70 (0.08)
8 (0.06)
-
0.41 [0.07, 0.74]
1
0
63 (0.07)
8 (0.13)
-
0.32 [-0.03, 0.66]
6
0
53 (0.05)
10 (0.06)
-
0.01 [-0.27, 0.30]
5
0
83 (0.08)
10 (0.10)
-
0.26 [-0.12, 0.64]
3
0
115 (0.10)
13 (0.10)
-
-0.12 [-0.33, 0.09]
41
0
195 (0.14)
14 (0.10)
-
0.26 [-0.11, 0.62]
1
0
97 (0.06)
8 (0.05)
-
-
-
-
116 (0.06)
16 (0.06)
-
0.19 [-0.13, 0.50]
2
0
58 (0.03)
6 (0.06)
-
0.15 [-0.19, 0.48]
-
-
169 (0.05)
18 (0.04)
-
0.19 [-0.05, 0.44]
7
0
209 (0.05)
32 (0.05)
-
0.12 [-0.18, 0.42]
2
-
427 (0.07)
48 (0.07)
-
0.02 [-0.14, 0.18]
193
0