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Other specified/unspecified nutritional deficiencies

EFO MESH Endpoint Browser PheWeb

E4_NUTRI_DEF_NAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E63.8, E63.9, E63.9+I43.2
  • Hospital discharge: ICD-9 — 269[3-9]
  • Hospital discharge: ICD-8 — 2699
  • Hospital discharge: excluded ICD-8 — 26990
  • Cause of death: ICD-10 — E63.8, E63.9, E63.9+I43.2
  • Cause of death: ICD-9 — 269[3-9]
  • Cause of death: ICD-8 — 2699
  • Cause of death: excluded ICD-8 — 26990

2 out of 7 registries used, show all original rules.

269

4. Check minimum number of events

None

269

5. Include endpoints

None

269

6. Filter based on genotype QC (FinnGen only)

258

Control definitions (FinnGen only)

Control exclude
E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2818 1684 1106
Only index persons 2159 1300 859
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 33.04 38.23 24.56
Only index persons 25.04 32.24 14.14

-FinnGen-

Key figures

All Female Male
Number of individuals 258 157 101
Unadjusted period prevalence (%) 0.05 0.06 0.05
Median age at first event (years) 26.07 24.33 28.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
269
Matched controls
2690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
26998
ICD-8 Finland
Other nutritional deficiency, Aliae definitae
+∞
224.7
183
*
K90.0
ICD-10 Finland
Coeliac disease
18.6
62.3
53
35
26999
ICD-8 Finland
Other nutritional deficiency, Other and unspecified
+∞
46.2
43
*
Y0599
ICD-8 Finland
Investigation of digestive system
20.3
22.9
34
19
E63.9
ICD-10 Finland
Nutritional deficiency, unspecified
+∞
22.2
21
*
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
119.3
20.9
22
*
26900
ICD-8 Finland
Other nutritional deficiency, Sprue and steatorrhoea
+∞
16.8
16
*
E63.8
ICD-10 Finland
Other specified nutritional deficiencies
+∞
15.8
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
14.7
104
488
26910
ICD-8 Finland
Other nutritional deficiency, Malabsorption syndrome, unspecified
136.1
12.5
13
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
9.2
43
157
A03CA02
ATC
clidinium and psycholeptics; oral
4.0
8.6
25
67
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
8.4
8
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.5
8.1
20
47
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
7.8
37
136
A07EC02
ATC
mesalazine; oral, rectal
3.7
7.5
24
69
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
7.1
65
330
B01AA03
ATC
warfarin; systemic
2.3
6.7
56
274
127
Kela drug reimbursment
Transplant complication
10.4
6.6
12
12
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
6.6
21
60
UJF32
NOMESCO Finland
Coloscopy
2.1
6.6
74
408
C03CA01
ATC
furosemide; systemic
2.0
6.5
86
504
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.5
64
335
55130
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Diaphragmatic
71.5
6.5
7
*
28009
ICD-8 Finland
Iron deficiency anaemias, Unspecified
18.6
6.3
9
5
56419
ICD-8 Finland
Functional disorders of intestines, Colon irritabile aliud sive NUD
27.4
6.3
8
*
A46
ICD-10 Finland
Erysipelas
2.5
6.2
42
186
79399
ICD-8 Finland
Observation, without need for further medical care, Unspecified
10.4
6.1
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
89
472
2.32
9.02
2.8
1.9
2.71
3.04
mg/l
0.79
73
410
47
205
2.57
7.19
3.5
2.8
1.73
1.69
%
0.12
36
191
34
139
2.66
5.90
3.7
2.5
73.62
68.05
e9/l
0.46
26
109
98
618
1.92
5.88
6.9
4.1
7.41
7.40
ph
0.76
18
122
136
968
1.82
5.47
12.8
6.3
1.21
1.22
mmol/l
0.39
114
821
33
139
2.57
5.39
9.5
7.4
—
—
—
0
0
81
492
1.92
5.37
3.9
2.5
342.10
10969.05
umol/l
3.44
72
419
128
903
1.80
5.23
25.3
12.4
1.38
1.20
inr
1.25
40
278
124
877
1.77
4.95
7.7
4.0
35.30
35.89
g/l
0.66
113
817
49
264
2.05
4.51
3.4
2.4
22.29
24.19
%
0.35
44
226
59
346
1.90
4.26
2.2
1.7
1095.55
1167.68
nmol/l
0.24
42
255
34
163
2.24
4.20
5.5
3.6
—
—
—
0
0
77
498
1.77
4.04
1.7
1.2
1.36
1.53
u/ml
0.10
20
140
121
887
1.66
4.01
10.0
5.4
1.21
1.22
mmol/l
0.12
112
803
89
606
1.70
3.87
2.6
2.0
128.00
222.03
u/l
1.55
81
573
51
294
1.91
3.86
1.6
1.2
—
—
—
0
0
83
556
1.71
3.83
4.4
2.9
—
—
—
0
0
88
600
1.69
3.80
4.2
2.9
—
—
—
0
0
67
425
1.77
3.73
3.8
2.6
5.33
5.14
e6/l
0.05
60
382
61
378
1.79
3.67
5.5
3.1
1996.41
149.18
ng/l
0.74
49
284
126
950
1.61
3.63
8.0
5.5
2.82
2.79
%
0.04
118
891
90
624
1.66
3.62
4.7
3.1
33.72
144.72
e6/l
0.54
73
477
120
898
1.61
3.54
3.5
2.7
125.60
113.26
ug/l
0.27
113
839
45
258
1.89
3.46
2.5
2.2
80.42
107.47
ug/g
0.49
33
212
63
404
1.73
3.36
3.1
2.8
523.08
544.42
mosm/kgh2o
0.31
53
348
10
23
4.47
3.34
5.7
4.4
—
—
—
0
0
125
957
1.57
3.28
8.2
5.8
8.45
8.61
%
0.24
117
902
151
1208
1.57
3.27
11.3
9.2
4.13
4.04
e9/l
0.20
131
1066
69
458
1.68
3.24
1.8
1.6
19.41
22.32
nmol/l
0.69
62
394
136
1065
1.56
3.21
8.0
5.6
0.20
0.18
e9/l
0.47
123
948
122
933
1.56
3.20
8.1
5.5
0.65
0.67
%
0.25
114
874
191
1621
1.61
3.14
11.4
7.0
84.45
74.96
u/l
1.41
181
1521
68
454
1.67
3.11
1.6
1.4
2.36
2.45
g/l
0.15
33
293
131
1023
1.55
3.10
7.6
5.4
0.59
0.56
e9/l
0.65
115
904
41
237
1.86
3.07
1.9
1.6
—
—
—
0
0
131
1025
1.54
3.06
7.8
5.4
0.04
0.04
e9/l
0.36
115
905
126
979
1.54
3.03
8.1
5.7
26.72
27.69
%
0.42
118
926
36
201
1.91
3.00
7.1
6.4
5.37
5.05
kpa
1.38
36
191
125
972
1.53
2.98
7.3
5.5
58.04
57.45
%
0.21
117
918
36
202
1.90
2.95
7.1
6.5
1.37
1.11
mmol/l
0.19
31
156
80
564
1.60
2.93
4.6
2.9
0.22
0.42
e6/l
1.23
62
415
162
1336
1.53
2.92
6.6
4.5
4362.20
270.82
e6/l
—
5
34
98
727
1.55
2.87
5.6
3.6
140.81
102.35
e6/l
0.11
74
514
132
1046
1.51
2.84
7.9
5.4
1.86
1.80
e9/l
0.30
123
941
11
33
3.43
2.84
2.3
2.8
—
—
—
0
0
18
78
2.40
2.81
1.9
2.3
0.64
0.68
%
0.21
18
78
10
28
3.67
2.81
2.5
1.3
—
—
—
0
0
9
23
4.01
2.80
1.9
2.1
58.67
59.07
%
—
9
23
40
237
1.81
2.78
2.4
2.2
13.13
7.61
umol/l
0.57
32
207
50
318
1.70
2.73
4.0
2.8
2.99
2.69
e6/l
0.08
26
178
74
521
1.58
2.71
5.1
4.0
—
—
—
0
0
37
216
1.83
2.69
8.8
6.5
103.73
104.31
mmol/l
0.34
37
216
103
785
1.51
2.62
2.6
1.9
95.43
96.31
pmol/l
0.06
63
390
6
11
5.55
2.55
1.2
1.0
—
—
—
0
0
106
819
1.49
2.50
4.3
3.4
5.80
5.93
ph
—
5
77
38
229
1.77
2.50
1.5
1.3
—
—
—
0
0
73
522
1.55
2.48
8.9
6.5
—
—
—
0
0
126
1009
1.47
2.48
5.9
4.9
0.00
0.01
estimate
0.50
25
194
31
176
1.86
2.47
7.4
7.0
96.33
96.39
%
0.04
31
169
10
32
3.21
2.46
1.4
1.2
—
—
—
0
0
121
964
1.46
2.43
9.3
5.8
—
—
—
0
0
126
1013
1.46
2.41
4.6
3.7
0.00
0.00
estimate
0.50
27
203
18
84
2.22
2.41
10.3
6.8
—
—
—
0
0
60
414
1.58
2.37
1.8
1.7
127659965.51
441.04
pmol/l
0.49
47
346
84
625
1.50
2.36
3.4
2.2
—
—
—
0
0
15
67
2.31
2.22
4.3
3.7
0.48
0.21
g/l
—
5
28
54
372
1.57
2.15
1.2
1.2
4.84
8.76
u/ml
0.45
15
153
16
75
2.21
2.13
6.8
3.6
—
—
—
0
0
125
1021
1.42
2.12
4.7
3.7
0.00
0.00
estimate
-0.00
25
186
33
201
1.73
2.11
2.5
2.0
455.67
388.72
nmol/l
0.63
33
186
10
37
2.77
2.09
3.8
3.8
60.80
60.54
%
—
10
37
10
37
2.77
2.09
3.8
3.4
4.52
4.54
e9/l
—
10
37
7
20
3.56
2.07
2.6
1.5
—
—
—
0
0
20
104
2.00
2.06
9.2
8.6
93.67
94.82
%
0.88
20
104
181
1584
1.44
2.05
5.0
4.0
14.88
14.67
pmol/l
0.43
164
1448
89
689
1.44
2.01
3.6
3.2
2.34
2.35
mmol/l
0.37
76
610
53
370
1.54
1.99
1.8
1.8
—
—
—
0
0
33
205
1.70
1.97
1.9
1.5
—
—
—
0
0
229
2106
1.59
1.96
23.5
12.7
20.86
22.89
mg/l
0.51
190
1618
97
769
1.41
1.90
4.2
3.5
29.72
32.37
ng/l
0.15
59
514
231
2133
1.59
1.89
26.9
14.3
3.96
3.97
mmol/l
0.14
223
2068
7
22
3.24
1.89
1.7
1.2
—
—
—
0
0
230
2122
1.58
1.89
26.7
14.3
139.34
139.63
mmol/l
0.91
221
2061
27
161
1.75
1.87
4.6
4.6
0.00
0.13
%
1.49
13
48
163
1413
1.39
1.86
6.2
4.3
—
—
—
0
0
28
169
1.73
1.86
4.6
4.4
1.14
0.84
%
0.23
14
56
8
176
0.44
1.77
3.0
2.3
—
14.52
—
0
10
6
18
3.38
1.75
1.7
1.9
—
—
—
0
0
13
61
2.19
1.74
1.8
2.5
—
—
—
0
0
25
149
1.75
1.74
4.6
4.5
1.92
0.60
%
0.43
12
43
7
24
2.97
1.73
1.0
1.8
—
—
—
0
0
15
75
2.06
1.73
1.4
1.7
20.77
4.67
ug/l
0.55
15
70
176
1557
1.38
1.70
5.7
3.9
12.29
11.26
mm/h
0.45
160
1434
61
453
1.45
1.70
4.7
3.6
—
—
—
0
0
35
232
1.58
1.65
1.7
1.6
—
—
—
0
0
21
121
1.80
1.64
1.1
1.3
—
—
—
0
0
12
232
0.49
1.61
1.0
1.5
—
—
—
0
0
162
1422
1.35
1.60
4.1
2.9
66.63
43.00
u/l
1.34
148
1338
22
130
1.75
1.58
3.8
3.0
4.25
4.57
pmol/l
1.13
22
116
13
65
2.05
1.51
1.4
1.2
212.84
288.03
miu/ml
—
7
29
60
454
1.41
1.51
1.7
1.6
0.75
1.22
mg/l
1.93
50
350
28
180
1.62
1.50
1.4
1.2
—
—
—
0
0
26
164
1.65
1.50
8.0
7.1
117.23
123.04
g/l
0.76
26
159
7
154
0.44
1.48
1.1
1.3
—
36.51
—
0
12
12
59
2.08
1.46
2.0
2.3
—
—
—
0
0
52
386
1.43
1.45
1.3
1.3
19.63
32.59
iu/ml
0.88
18
134
7
29
2.45
1.40
1.3
1.2
—
—
—
0
0
235
2211
1.50
1.39
20.8
12.1
—
—
—
0
0
39
276
1.48
1.39
2.6
1.7
—
—
—
0
0
68
533
1.37
1.39
5.1
3.1
47.69
296.29
mg/l
0.76
40
342
103
861
1.32
1.37
2.0
2.2
—
—
—
0
0
40
286
1.47
1.36
1.6
1.6
—
—
—
0
0
206
1898
1.36
1.35
6.0
4.7
1.85
1.86
mu/l
0.00
188
1744
22
137
1.66
1.34
1.6
2.1
—
—
—
0
0
109
923
1.30
1.31
11.7
9.0
0.00
0.00
e9/l
0.63
88
759
6
24
2.53
1.31
3.8
2.3
—
—
—
0
0
23
147
1.62
1.28
1.4
1.5
—
—
—
0
0
58
450
1.37
1.26
5.2
4.1
1.01
1.02
kg/l
—
6
59
5
19
2.66
1.22
1.2
1.4
—
—
—
0
0
19
117
1.67
1.22
4.4
2.9
—
—
—
0
0
14
79
1.81
1.19
1.8
1.7
—
—
—
0
0
18
110
1.68
1.19
9.6
7.9
1.79
1.47
%
0.21
18
110
18
110
1.68
1.19
10.1
8.1
0.90
0.72
%
0.55
18
110
51
393
1.37
1.16
3.3
2.8
2.44
2.45
mmol/l
0.26
39
342
5
20
2.53
1.15
2.2
2.2
—
—
—
0
0
5
20
2.53
1.15
1.4
1.7
31.40
32.00
pg
—
5
20
71
577
1.31
1.14
5.4
3.0
6.45
7.45
mmol/l
1.21
60
490
12
66
1.86
1.11
4.5
2.4
1.80
1.43
mg/l
0.60
12
57
22
145
1.56
1.10
1.5
1.4
—
—
—
0
0
35
255
1.43
1.10
1.3
1.3
—
—
—
0
0
8
41
1.98
1.09
2.3
1.6
—
—
—
0
0
69
565
1.30
1.04
5.3
3.7
9.61
6.60
mg/mmol
0.33
39
348
40
302
1.38
1.03
1.3
1.3
448.00
544.32
titre
—
5
74
23
156
1.52
1.02
5.2
4.5
0.00
0.23
%
—
9
43
235
2240
1.39
1.00
15.1
9.6
26.83
25.71
u/l
0.46
225
2165
5
23
2.20
0.98
2.4
2.7
—
—
—
0
0
10
54
1.88
0.98
3.8
4.2
1.60
1.15
mmol/l
—
10
45
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
67
552
1.28
0.97
5.7
3.9
0.00
0.01
estimate
0.50
22
188
18
120
1.54
0.88
3.5
4.0
—
—
—
0
0
8
139
0.56
0.85
1.1
1.4
—
—
—
0
0
158
1452
1.21
0.82
4.3
3.6
—
—
—
0
0
66
555
1.25
0.81
5.0
3.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
0.31
—
0
17
0
24
0.00
0.79
0.0
1.5
—
6.66
—
0
17
0
24
0.00
0.79
0.0
1.5
—
2.82
—
0
16
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
199
1881
1.22
0.73
6.7
5.3
40.39
39.43
mmol/mol
0.66
181
1764
7
41
1.73
0.70
6.4
1.9
—
—
—
0
0
7
41
1.73
0.70
7.4
2.1
2.07
2.48
mmol/l
—
7
25
11
69
1.62
0.69
2.6
1.7
—
—
—
0
0
7
42
1.68
0.69
1.1
1.2
—
—
—
0
0
7
42
1.68
0.69
2.6
1.9
—
—
—
0
0
23
171
1.38
0.68
4.3
3.6
—
—
—
0
0
23
171
1.38
0.68
14.3
4.1
—
—
—
0
0
7
43
1.64
0.67
1.3
1.6
—
—
—
0
0
15
103
1.48
0.66
2.7
2.3
—
—
—
0
0
7
44
1.61
0.65
1.0
3.8
—
—
—
0
0
242
2347
1.31
0.63
33.6
19.0
252.73
249.59
e9/l
0.28
235
2289
242
2347
1.31
0.63
33.4
18.9
91.26
90.83
fl
0.65
237
2314
242
2347
1.31
0.63
33.9
19.0
39.04
40.29
%
2.00
227
2213
206
1966
1.20
0.61
4.4
3.8
1.34
1.24
mmol/l
0.68
190
1820
242
2349
1.30
0.60
33.4
18.9
30.33
30.26
pg
0.21
237
2315
242
2349
1.30
0.60
33.5
19.0
6.72
6.56
e9/l
0.59
234
2279
242
2349
1.30
0.60
33.6
19.0
4.40
4.49
e12/l
2.19
234
2283
0
21
0.00
0.60
0.0
1.4
—
79.00
—
0
21
242
2351
1.29
0.58
33.8
19.1
132.26
135.41
g/l
2.79
237
2314
16
115
1.42
0.58
3.4
7.3
24.66
24.73
mmol/l
0.03
16
109
6
36
1.68
0.57
4.7
4.4
12.83
10.55
mmol/l
—
6
31
6
36
1.68
0.57
4.7
4.4
104.17
105.48
mmol/l
—
6
31
218
2097
1.21
0.56
5.2
4.7
2.74
2.81
mmol/l
0.55
200
1949
6
37
1.64
0.56
1.7
2.1
—
—
—
0
0
8
125
0.63
0.56
1.4
1.8
—
—
—
0
0
12
82
1.49
0.55
7.8
3.2
25.13
24.83
mmol/l
0.16
12
82
6
38
1.59
0.54
4.7
2.1
—
—
—
0
0
25
313
0.78
0.53
2.4
2.8
0.55
0.85
ug/l
1.61
14
200
21
162
1.32
0.52
7.0
3.0
—
—
—
0
0
14
101
1.41
0.50
1.1
1.1
—
—
—
0
0
31
254
1.25
0.50
1.9
1.3
—
—
—
0
0
7
45
1.57
0.49
1.1
1.6
—
—
—
0
0
7
46
1.54
0.48
7.4
2.2
7.43
7.42
ph
—
7
40
206
1985
1.16
0.45
5.2
4.2
5.93
5.86
mmol/l
0.23
187
1829
19
239
0.78
0.43
1.1
1.3
—
—
—
0
0
8
57
1.42
0.42
1.3
1.1
—
—
—
0
0
230
2239
1.19
0.41
26.9
14.7
82.03
75.86
umol/l
0.95
230
2239
0
15
0.00
0.41
0.0
1.0
—
261.90
—
0
10
8
60
1.34
0.40
1.3
1.2
—
—
—
0
0
5
34
1.48
0.40
1.0
1.0
12.34
0.43
u/ml
—
5
12
7
104
0.66
0.40
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
9
68
1.33
0.38
2.7
4.9
—
—
—
0
0
9
69
1.31
0.37
2.6
1.6
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
6
47
1.28
0.32
2.3
1.5
4.64
4.86
mmol/24h
—
6
41
7
57
1.23
0.29
3.1
1.9
—
—
—
0
0
11
86
1.29
0.26
1.2
1.2
—
—
—
0
0
9
73
1.24
0.25
1.4
1.1
—
—
—
0
0
5
40
1.25
0.22
1.2
1.2
154.00
240.26
u/ml
—
5
25
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
5
42
1.19
0.21
2.4
2.7
6.66
7.74
mmol/l
—
5
42
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
69.00
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
16.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
16
136
1.19
0.20
1.1
1.2
—
—
—
0
0
20
174
1.16
0.20
1.4
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
6.4
—
—
—
0
0
62
581
1.09
0.20
4.0
3.4
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
535.14
430.95
mg/l
—
7
55
209
2054
1.08
0.17
4.7
4.1
1.46
1.49
mmol/l
0.40
192
1914
8
71
1.13
0.16
5.6
4.3
1.73
1.42
%
—
8
65
9
83
1.09
0.15
2.6
1.5
—
—
—
0
0
209
2060
1.07
0.13
4.9
4.2
4.67
4.72
mmol/l
0.22
193
1924
50
528
0.93
0.13
3.7
4.6
1.75
2.81
ug/l
0.90
41
475
5
44
1.14
0.10
2.4
2.7
1.52
1.46
mmol/l
—
5
44
10
87
1.16
0.09
2.4
1.5
—
—
—
0
0
6
54
1.11
0.09
1.0
1.2
5.60
3.75
mmol/l
—
6
47
6
54
1.11
0.09
2.8
4.4
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
1.17
3.00
e6/l
—
6
43
6
55
1.09
0.09
1.2
1.3
22.00
200.67
e6/l
—
6
45
5
63
0.79
0.08
1.8
4.6
3.86
3.91
mmol/l
—
5
63
10
88
1.14
0.08
2.4
1.5
—
—
—
0
0
10
88
1.14
0.08
2.4
1.5
—
—
—
0
0
6
72
0.83
0.07
1.8
5.3
0.92
1.37
mmol/l
—
6
72
9
88
1.02
0.07
2.4
1.5
—
—
—
0
0
77
788
0.97
0.06
2.9
2.8
—
—
—
0
0
53
543
0.97
0.04
1.4
1.4
—
—
—
0
0
55
542
1.02
0.01
1.7
1.6
1.49
1.33
mmol/l
0.45
45
456
21
217
0.97
0.01
1.8
1.7
—
—
—
0
0
17
171
0.99
0.00
1.8
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
1.86
—
0
6
7
71
0.99
-0.00
4.9
4.4
1.20
0.85
%
—
7
66
0
6
0.00
-0.00
0.0
2.2
—
3085.50
—
0
6
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
7
70
1.00
-0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
90
1.00
-0.00
3.2
3.8
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.22
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
65.67
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.16
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_NUTRI_DEF_NAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_NUTRI_DEF_NAS 3.366 [2.28, 4.96] < 0.001
Birth year 0.992 [0.98, 1.0] 0.064

During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 230 females with E4_NUTRI_DEF_NAS died.

Males

Parameter HR [95% CI] p-value
E4_NUTRI_DEF_NAS 4.555 [2.46, 8.43] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 157 males with E4_NUTRI_DEF_NAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_NUTRI_DEF_NAS.

N-year risk Females Males
1 0.247% 0.866%
5 1.609% 5.4%
10 4.136% 12.203%
15 8.068% 22.754%
20 14.903% 35.897%

Relationships between endpoints

↥

Index endpoint: E4_NUTRI_DEF_NAS – Other specified/unspecified nutritional deficiencies

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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