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Other specified/unspecified nutritional deficiencies

EFO MESH Endpoint Browser PheWeb

E4_NUTRI_DEF_NAS

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E63.8, E63.9, E63.9+I43.2
  • Hospital discharge: ICD-9 — 269[3-9]
  • Hospital discharge: ICD-8 — 2699
  • Hospital discharge: excluded ICD-8 — 26990
  • Cause of death: ICD-10 — E63.8, E63.9, E63.9+I43.2
  • Cause of death: ICD-9 — 269[3-9]
  • Cause of death: ICD-8 — 2699
  • Cause of death: excluded ICD-8 — 26990

2 out of 7 registries used, show all original rules.

268

4. Check minimum number of events

None

268

5. Include endpoints

None

268

6. Filter based on genotype QC (FinnGen only)

268

Control definitions (FinnGen only)

Control exclude
E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2818 1684 1106
Only index persons 2159 1300 859
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 33.04 38.23 24.56
Only index persons 25.04 32.24 14.14

-FinnGen-

Key figures

All Female Male
Number of individuals 268 162 106
Unadjusted period prevalence (%) 0.05 0.06 0.05
Median age at first event (years) 26.17 24.50 28.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
248
Matched controls
2478
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
26998
ICD-8 Finland
Other nutritional deficiency, Aliae definitae
+∞
207.6
169
*
26999
ICD-8 Finland
Other nutritional deficiency, Other and unspecified
+∞
43.0
40
*
K90.0
ICD-10 Finland
Coeliac disease
25.8
35.7
50
24
E63.9
ICD-10 Finland
Nutritional deficiency, unspecified
+∞
21.1
20
*
Y0599
ICD-8 Finland
Investigation of digestive system
20.6
21.0
31
17
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
114.2
19.9
21
*
E63.8
ICD-10 Finland
Other specified nutritional deficiencies
+∞
14.7
14
*
26900
ICD-8 Finland
Other nutritional deficiency, Sprue and steatorrhoea
79.6
13.7
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
11.9
93
430
26910
ICD-8 Finland
Other nutritional deficiency, Malabsorption syndrome, unspecified
51.9
8.7
10
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
82.5
7.5
8
*
78880
ICD-8 Finland
Other general symptoms, Pyrexia of unknown origin
71.6
6.5
7
*
28009
ICD-8 Finland
Iron deficiency anaemias, Unspecified
18.6
6.3
9
5
A03CA02
ATC
clidinium and psycholeptics; oral
4.3
6.3
22
55
00919
ICD-8 Finland
Diarrhoeal disease, Diarrhoea
+∞
6.3
6
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
27.4
6.3
8
*
E66.01
ICD-10 Finland
Obesity due to excess calories
13.0
6.1
10
8
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
5.8
6.1
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
88
476
2.26
8.44
2.8
1.9
2.7
3.0
mg/l
0.68
72
415
46
206
2.49
6.65
3.5
2.8
1.7
1.7
%
0.06
35
192
97
619
1.89
5.57
6.9
4.1
7.4
7.4
ph
0.76
18
122
33
140
2.55
5.32
9.5
7.7
—
—
—
0
0
33
141
2.53
5.24
3.8
2.5
73.6
68.5
e9/l
0.42
26
111
135
970
1.79
5.18
12.8
6.4
1.2
1.2
mmol/l
0.34
113
816
80
494
1.88
5.01
3.9
2.5
342.9
10995.5
umol/l
3.44
71
418
112
770
1.78
4.93
18.3
7.5
1.4
1.2
inr
1.38
35
250
123
880
1.74
4.64
7.6
4.0
35.3
35.9
g/l
0.63
112
821
59
347
1.90
4.22
2.3
1.7
1095.5
1164.2
nmol/l
0.22
42
256
34
163
2.24
4.20
5.5
3.6
—
—
—
0
0
48
265
1.99
4.13
3.4
2.4
22.5
23.9
%
0.24
43
227
10
23
4.48
4.12
5.7
4.4
—
—
—
0
0
76
494
1.75
3.91
1.7
1.2
1.4
1.5
u/ml
0.10
20
141
51
293
1.91
3.90
1.6
1.2
—
—
—
0
0
87
592
1.70
3.79
4.1
2.9
—
—
—
0
0
120
889
1.63
3.75
10.0
5.5
1.2
1.2
mmol/l
0.09
111
801
61
377
1.80
3.71
5.5
3.1
1996.4
149.2
ng/l
0.74
49
284
67
426
1.76
3.70
3.8
2.6
5.5
5.2
e6/l
0.06
60
379
88
605
1.68
3.67
2.6
2.0
129.4
222.3
u/l
1.51
80
572
82
556
1.68
3.59
4.4
2.9
—
—
—
0
0
45
259
1.89
3.42
2.5
2.3
80.4
106.5
ug/g
0.47
33
213
125
951
1.59
3.42
8.0
5.6
2.8
2.8
%
0.10
117
890
89
624
1.64
3.40
4.8
3.1
34.1
144.7
e6/l
0.53
72
477
41
230
1.92
3.36
29.0
23.1
1.3
1.3
inr
—
5
28
119
901
1.58
3.29
3.5
2.7
124.2
112.8
ug/l
0.24
112
841
11
33
3.43
3.23
2.3
3.0
—
—
—
0
0
10
28
3.67
3.22
2.5
1.3
—
—
—
0
0
30
155
2.05
3.09
7.8
5.8
1.3
1.4
mmol/l
0.22
30
149
124
958
1.55
3.08
8.2
5.8
8.4
8.6
%
0.27
116
903
150
1210
1.54
3.05
11.3
9.4
4.1
4.0
e9/l
0.28
130
1067
61
398
1.69
3.04
3.0
2.6
523.8
553.6
mosm/kgh2o
0.44
50
342
41
238
1.85
3.03
1.9
1.6
—
—
—
0
0
135
1066
1.54
3.02
8.0
5.7
0.2
0.2
e9/l
0.52
122
947
121
935
1.54
2.97
8.2
5.5
0.6
0.7
%
0.27
113
876
36
202
1.90
2.95
7.1
6.6
5.4
5.1
kpa
1.23
36
192
190
1623
1.59
2.94
11.4
7.0
84.7
75.0
u/l
1.45
180
1521
36
203
1.89
2.91
7.1
6.7
1.3
1.1
mmol/l
0.11
30
155
67
453
1.64
2.91
1.6
1.4
2.4
2.5
g/l
0.18
33
293
130
1024
1.52
2.90
7.6
5.4
0.6
0.6
e9/l
0.60
114
900
68
463
1.63
2.87
1.8
1.5
19.6
22.4
nmol/l
0.67
61
398
130
1027
1.52
2.85
7.9
5.4
0.0
0.0
e9/l
0.33
114
905
125
980
1.52
2.84
8.1
5.7
26.7
27.7
%
0.44
117
924
40
236
1.82
2.82
2.4
2.2
13.1
7.6
umol/l
0.57
32
205
9
23
4.01
2.80
1.9
2.1
58.7
59.6
%
—
9
23
124
973
1.51
2.79
7.3
5.5
57.9
57.5
%
0.14
116
918
161
1337
1.51
2.74
6.7
4.5
4362.2
272.2
e6/l
—
5
34
79
564
1.57
2.73
4.6
3.0
0.2
0.4
e6/l
1.19
61
413
97
726
1.53
2.71
5.6
3.7
142.7
102.6
e6/l
0.11
73
513
10
32
3.21
2.67
1.4
1.2
—
—
—
0
0
131
1047
1.49
2.66
7.9
5.4
1.9
1.8
e9/l
0.30
122
936
6
11
5.55
2.55
1.2
1.0
—
—
—
0
0
88
652
1.52
2.55
10.0
5.2
—
—
—
0
0
73
523
1.54
2.46
5.1
4.0
—
—
—
0
0
38
231
1.75
2.43
1.5
1.3
—
—
—
0
0
31
177
1.85
2.43
7.4
7.3
96.3
96.1
%
0.12
31
170
18
84
2.23
2.41
10.3
6.8
—
—
—
0
0
102
788
1.48
2.39
2.6
1.9
96.2
96.1
pmol/l
0.01
62
392
125
1005
1.46
2.39
6.0
5.0
0.0
0.0
estimate
0.50
25
192
60
416
1.57
2.33
1.8
1.7
127659965.5
443.3
pmol/l
0.49
47
348
72
521
1.52
2.31
9.1
6.6
—
—
—
0
0
124
1004
1.44
2.24
4.7
3.7
0.0
0.0
estimate
0.00
25
190
83
626
1.47
2.17
3.5
2.2
—
—
—
0
0
15
68
2.28
2.15
4.3
3.7
0.5
0.2
g/l
—
5
29
54
372
1.57
2.15
1.2
1.2
4.8
8.8
u/ml
0.46
15
152
124
1016
1.41
2.05
4.7
3.7
0.0
0.0
estimate
0.00
25
184
10
38
2.69
2.03
3.8
3.3
4.5
4.5
e9/l
—
10
38
10
38
2.69
2.03
3.8
3.8
60.8
60.5
%
—
10
38
7
21
3.39
1.98
1.7
1.2
—
—
—
0
0
20
106
1.96
1.97
9.2
8.8
93.7
94.4
%
0.38
20
106
16
78
2.12
1.95
6.8
3.5
—
—
—
0
0
180
1581
1.42
1.95
5.0
4.0
14.9
14.7
pmol/l
0.40
163
1447
32
199
1.69
1.91
1.8
1.5
—
—
—
0
0
89
695
1.42
1.90
3.6
3.2
2.3
2.4
mmol/l
0.37
76
611
228
2103
1.56
1.85
23.4
12.8
20.7
22.9
mg/l
0.54
189
1618
32
201
1.67
1.85
2.4
2.0
459.7
389.1
nmol/l
0.66
32
186
230
2128
1.57
1.81
26.9
14.4
4.0
4.0
mmol/l
0.10
222
2062
229
2117
1.56
1.81
26.6
14.4
139.4
139.6
mmol/l
0.65
220
2055
27
163
1.73
1.79
4.6
4.6
0.0
0.1
%
—
9
44
28
171
1.71
1.79
4.6
4.4
1.6
0.7
%
—
10
49
8
176
0.44
1.77
3.0
2.3
—
13.0
—
0
8
6
18
3.38
1.75
1.7
1.9
—
—
—
0
0
96
769
1.39
1.75
4.2
3.5
29.7
32.5
ng/l
0.16
59
512
13
61
2.19
1.74
1.8
2.5
—
—
—
0
0
15
75
2.06
1.73
1.4
1.7
20.8
4.7
ug/l
0.55
15
70
162
1413
1.37
1.73
6.3
4.3
—
—
—
0
0
52
374
1.48
1.70
1.8
1.8
—
—
—
0
0
25
151
1.72
1.67
4.6
4.4
0.7
0.4
%
—
6
30
21
121
1.80
1.64
1.1
1.3
—
—
—
0
0
6
20
3.04
1.59
2.5
1.5
—
—
—
0
0
60
451
1.43
1.56
4.8
3.6
—
—
—
0
0
175
1558
1.36
1.56
5.7
3.9
12.4
11.3
mm/h
0.45
159
1435
22
131
1.74
1.55
3.8
3.0
4.2
4.6
pmol/l
1.13
22
116
12
227
0.51
1.52
1.0
1.5
—
—
—
0
0
26
164
1.65
1.50
8.0
7.3
117.2
122.7
g/l
0.70
26
158
35
238
1.54
1.49
1.7
1.6
—
—
—
0
0
7
154
0.44
1.48
1.1
1.3
—
35.1
—
0
11
13
66
2.02
1.46
1.4
1.2
212.8
278.8
miu/ml
—
7
30
12
59
2.08
1.46
2.0
2.4
—
—
—
0
0
52
388
1.42
1.41
1.3
1.3
19.6
32.9
iu/ml
0.91
18
132
7
29
2.45
1.40
1.3
1.2
—
—
—
0
0
103
863
1.31
1.35
2.0
2.2
—
—
—
0
0
68
536
1.36
1.34
5.1
3.1
47.7
297.4
mg/l
0.76
40
340
59
455
1.38
1.33
1.7
1.6
0.7
1.2
mg/l
2.38
49
349
234
2206
1.48
1.32
20.8
12.2
—
—
—
0
0
39
279
1.47
1.32
2.6
1.7
—
—
—
0
0
58
447
1.38
1.31
5.2
4.1
1.0
1.0
kg/l
—
6
59
22
138
1.65
1.31
1.6
2.0
—
—
—
0
0
27
180
1.56
1.27
1.4
1.2
—
—
—
0
0
40
291
1.44
1.25
1.6
1.6
—
—
—
0
0
6
25
2.43
1.25
3.8
2.2
—
—
—
0
0
5
19
2.66
1.22
1.2
1.4
—
—
—
0
0
5
19
2.66
1.22
1.4
1.7
31.4
32.1
pg
—
5
19
19
117
1.67
1.22
4.4
2.9
—
—
—
0
0
14
79
1.81
1.19
1.8
1.7
—
—
—
0
0
204
1892
1.33
1.17
6.0
4.7
1.9
1.9
mu/l
0.01
186
1738
108
925
1.28
1.17
11.8
9.1
0.0
0.0
e9/l
0.63
87
757
23
151
1.57
1.16
1.4
1.5
—
—
—
0
0
5
20
2.53
1.15
2.2
2.2
—
—
—
0
0
18
111
1.67
1.15
10.1
8.4
0.9
0.7
%
0.54
18
111
7
137
0.50
1.13
1.1
1.4
—
—
—
0
0
18
112
1.65
1.12
9.6
8.2
1.8
1.5
%
0.17
18
112
8
41
1.98
1.09
2.3
1.6
—
—
—
0
0
10
52
1.96
1.07
3.8
4.3
1.6
1.2
mmol/l
—
10
43
40
300
1.39
1.07
1.3
1.3
448.0
549.6
titre
—
5
73
12
67
1.83
1.06
4.5
2.4
1.8
1.4
mg/l
0.61
12
58
67
547
1.30
1.04
5.7
4.0
0.0
0.0
estimate
0.50
22
186
5
22
2.30
1.04
2.0
2.4
—
—
—
0
0
35
258
1.41
1.04
1.3
1.3
—
—
—
0
0
69
567
1.29
1.02
5.6
4.0
9.6
6.6
mg/mmol
0.34
39
351
70
578
1.29
0.99
5.4
3.0
6.5
7.4
mmol/l
1.07
59
484
5
23
2.20
0.98
2.4
2.7
—
—
—
0
0
21
141
1.53
0.98
1.5
1.3
—
—
—
0
0
50
395
1.33
0.98
3.4
2.8
2.4
2.5
mmol/l
0.37
38
345
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
234
2232
1.38
0.97
15.1
9.6
26.9
25.7
u/l
0.49
224
2156
23
158
1.50
0.97
5.2
4.5
0.0
0.2
%
—
8
40
18
118
1.56
0.93
3.5
4.1
—
—
—
0
0
6
30
2.02
0.87
1.2
1.4
—
—
—
0
0
205
1936
1.25
0.81
24.7
13.5
38.3
40.2
%
1.83
149
1466
0
25
0.00
0.79
0.0
1.6
—
6.7
—
0
17
0
25
0.00
0.79
0.0
1.6
—
2.8
—
0
16
0
25
0.00
0.79
0.0
1.6
—
0.3
—
0
17
0
26
0.00
0.79
0.0
1.5
—
—
—
0
0
66
558
1.24
0.77
5.0
3.7
—
—
—
0
0
157
1447
1.21
0.77
4.3
3.6
—
—
—
0
0
7
41
1.73
0.70
7.4
2.1
2.1
2.5
mmol/l
—
7
25
7
41
1.73
0.70
6.4
1.9
—
—
—
0
0
7
41
1.73
0.70
1.1
1.2
—
—
—
0
0
23
170
1.39
0.70
4.3
3.7
—
—
—
0
0
15
102
1.50
0.69
2.7
2.4
—
—
—
0
0
7
42
1.68
0.69
2.6
1.9
—
—
—
0
0
7
42
1.68
0.69
1.3
1.6
—
—
—
0
0
198
1878
1.21
0.66
6.8
5.4
40.5
39.5
mmol/mol
0.68
180
1761
23
172
1.37
0.66
14.3
4.2
—
—
—
0
0
11
70
1.60
0.66
2.6
1.6
—
—
—
0
0
7
44
1.61
0.65
1.0
3.8
—
—
—
0
0
24
311
0.75
0.64
2.4
2.8
0.5
0.8
ug/l
1.63
14
199
241
2339
1.30
0.60
33.5
19.2
252.7
249.7
e9/l
0.26
234
2281
241
2339
1.30
0.60
33.3
19.1
91.3
90.8
fl
0.67
236
2306
241
2341
1.29
0.58
33.3
19.1
30.3
30.2
pg
0.20
236
2307
241
2341
1.29
0.58
33.6
19.2
6.7
6.6
e9/l
0.58
233
2271
241
2341
1.29
0.58
33.6
19.2
4.4
4.5
e12/l
2.11
233
2275
6
35
1.73
0.58
4.7
4.5
104.2
105.4
mmol/l
—
6
30
6
35
1.73
0.58
4.7
4.5
12.8
10.5
mmol/l
—
6
30
12
81
1.50
0.58
7.8
3.2
25.1
24.8
mmol/l
0.17
12
81
205
1960
1.20
0.58
4.4
3.8
1.3
1.2
mmol/l
0.72
189
1812
241
2342
1.29
0.57
33.8
19.3
132.3
135.4
g/l
2.64
236
2305
8
55
1.47
0.56
1.3
1.1
—
—
—
0
0
8
125
0.63
0.56
1.4
1.8
—
—
—
0
0
6
38
1.59
0.54
1.7
2.1
—
—
—
0
0
217
2090
1.20
0.53
5.2
4.7
2.7
2.8
mmol/l
0.43
199
1937
14
100
1.42
0.53
1.1
1.1
—
—
—
0
0
21
162
1.32
0.52
7.1
3.1
—
—
—
0
0
7
45
1.57
0.49
1.1
1.6
—
—
—
0
0
7
46
1.54
0.48
7.4
2.2
7.4
7.4
ph
—
7
39
31
257
1.23
0.45
1.9
1.3
—
—
—
0
0
55
483
1.17
0.45
4.5
4.8
—
—
—
0
0
205
1978
1.15
0.42
5.2
4.2
5.9
5.9
mmol/l
0.21
186
1823
0
15
0.00
0.41
0.0
1.0
—
261.9
—
0
10
7
104
0.66
0.40
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
8
61
1.32
0.40
1.3
1.2
—
—
—
0
0
229
2232
1.18
0.39
26.8
14.8
82.2
75.9
umol/l
0.99
229
2232
9
67
1.36
0.38
2.6
1.6
—
—
—
0
0
9
68
1.33
0.38
2.7
4.9
—
—
—
0
0
19
233
0.80
0.36
1.1
1.4
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
6
47
1.28
0.32
1.8
2.0
7.9
8.2
kpa
—
6
41
7
57
1.23
0.29
3.1
2.1
—
—
—
0
0
9
73
1.24
0.25
1.4
1.1
—
—
—
0
0
11
87
1.28
0.24
1.2
1.2
—
—
—
0
0
5
38
1.32
0.23
5.4
2.1
—
—
—
0
0
5
39
1.29
0.23
1.2
1.2
154.0
240.3
u/ml
—
5
25
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
62
578
1.09
0.22
4.0
3.4
—
—
—
0
0
5
42
1.19
0.21
2.4
2.7
6.7
7.7
mmol/l
—
5
42
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
69.0
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
16.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
16
136
1.19
0.20
1.1
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
6.4
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
535.1
430.9
mg/l
—
7
55
20
177
1.14
0.17
1.4
1.3
—
—
—
0
0
8
70
1.15
0.16
5.6
4.4
1.7
1.4
%
—
8
64
49
522
0.92
0.16
3.7
4.6
1.8
2.8
ug/l
0.87
40
470
208
2047
1.07
0.15
4.7
4.2
1.5
1.5
mmol/l
0.35
191
1902
9
82
1.10
0.15
2.6
1.6
—
—
—
0
0
208
2053
1.06
0.12
4.9
4.2
4.7
4.7
mmol/l
0.11
192
1912
10
86
1.17
0.11
2.4
1.6
—
—
—
0
0
5
44
1.14
0.10
2.4
2.8
1.5
1.5
mmol/l
—
5
44
10
87
1.16
0.09
2.4
1.5
—
—
—
0
0
10
87
1.16
0.09
2.4
1.6
—
—
—
0
0
6
54
1.11
0.09
1.0
1.2
5.6
3.7
mmol/l
—
6
47
6
54
1.11
0.09
2.8
4.4
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
1.2
3.0
e6/l
—
6
43
6
55
1.09
0.09
1.2
1.3
22.0
200.7
e6/l
—
6
45
5
62
0.80
0.08
1.8
4.7
3.9
3.9
mmol/l
—
5
56
6
71
0.84
0.07
1.8
5.3
0.9
1.4
mmol/l
—
6
71
76
780
0.96
0.07
2.9
2.8
—
—
—
0
0
9
87
1.04
0.07
2.4
1.6
—
—
—
0
0
16
171
0.93
0.05
1.9
1.6
—
—
—
0
0
53
544
0.97
0.04
1.4
1.4
—
—
—
0
0
21
218
0.96
0.02
1.8
1.7
—
—
—
0
0
54
541
1.00
0.00
1.8
1.7
1.5
1.3
mmol/l
0.44
44
456
9
90
1.00
0.00
3.2
3.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
3085.5
—
0
6
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
1.9
—
0
6
7
70
1.00
0.00
4.9
4.4
1.2
0.8
%
—
7
65
7
71
0.99
0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
1.2
—
0
5
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
65.7
—
0
5
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
6.2
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint E4_NUTRI_DEF_NAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_NUTRI_DEF_NAS 3.366 [2.28, 4.96] < 0.001
Birth year 0.992 [0.98, 1.0] 0.064

During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 230 females with E4_NUTRI_DEF_NAS died.

Males

Parameter HR [95% CI] p-value
E4_NUTRI_DEF_NAS 4.555 [2.46, 8.43] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 157 males with E4_NUTRI_DEF_NAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_NUTRI_DEF_NAS.

N-year risk Females Males
1 0.247% 0.866%
5 1.609% 5.4%
10 4.136% 12.203%
15 8.068% 22.754%
20 14.903% 35.897%

Relationships between endpoints

↥

Index endpoint: E4_NUTRI_DEF_NAS – Other specified/unspecified nutritional deficiencies

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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