Benign neoplasm: Mediastinum

CD2_BENIGN_MEDIASTINUM

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D15.2& Hospital discharge: ICD-9 — 2125 Hospital discharge: ICD-8 — 2125 Cause of death: ICD-10 — D15.2& Cause of death: ICD-9 — 2125 Cause of death: ICD-8 — 2125 2 out of 7 registries used, show all original rules.	124
4. Check minimum number of events None	124
5. Include endpoints None	124
6. Filter based on genotype QC (FinnGen only)	116

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D15
Name in latin: Neoplasma benignum mediastini

NAME	CD2_BENIGN_MEDIASTINUM
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D152
HD_ICD_9	2125
HD_ICD_8	2125
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D152
COD_ICD_9	2125
COD_ICD_8	2125
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Mediastinum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	865	500	354
Only index persons	693	417	276
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.02	0.01
Median age at first event (years)
Whole population	47.33	49.66	43.59
Only index persons	43.93	47.08	39.17

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	116	69	47
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	50.44	50.28	50.68

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
124: Matched controls
1240

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D15.2

ICD-10 Finland

Benign neoplasm: Mediastinum

+∞

115.3

D38.3

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Mediastinum

170.8

26.8

21250

ICD-8 Finland

Benign neoplasm of respiratory system, Mediastinum

+∞

24.8

GEB30

NOMESCO Finland

Mediastinotomy and excision of lesion

+∞

20.4

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

6.8

19.6

GEC24

NOMESCO Finland

Thoracoscopic thymectomy

+∞

16.0

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

4.3

12.0

124

D15.0

ICD-10 Finland

Benign neoplasm: Thymus

+∞

11.6

2125A

ICD-9 Finland

Benign neoplasm of respiratory and intrathoracic organs, Mediastinum

+∞

10.6

ZXD10

NOMESCO Finland

Scheduled procedure

3.2

9.5

331

GD1AA

NOMESCO Finland

Thorax X-ray examination

3.3

9.3

433

R4110

NOMESCO Finland

Physiotherapy

3.1

8.3

236

WX408

NOMESCO Finland

General anesthesy, balanced

3.0

7.9

227

GEC23

NOMESCO Finland

Transsternal thymectomy

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

492

3.44

9.47

6.6

7.8

1.19

1.22

mmol/l

1.89

427

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.67

7.88

5.8

10.3

—

(3000991) Gas panel - Venous blood

3.77

7.85

6.7

10.1

—

(3022217) INR in Platelet poor plasma by Coagulation assay

486

2.92

7.50

10.4

10.6

1.20

1.21

inr

0.04

142

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

261

2.80

7.08

2.3

2.4

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

109

3.31

6.82

7.0

7.8

5.32

5.21

kpa

0.34

104

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.69

6.05

5.7

6.3

24.70

25.06

mmol/l

0.17

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

492

2.49

5.65

2.6

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

347

2.41

5.44

3.2

3.0

35.03

30.08

u/l

0.30

329

(3002256) Pathology report gross observation

136

2.59

4.48

1.2

1.3

—

(3018418) pH of Serum or Plasma

322

2.20

4.33

3.9

4.1

7.39

7.40

—

(3044640) Blood type and Crossmatch panel - Blood

353

2.14

4.11

2.8

2.4

—

(4035726) Immunohistochemistry procedure

109

2.62

4.01

1.5

1.3

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

190

2.26

3.82

3.5

3.2

78.63

69.35

ng/l

0.06

153

(3037467) Urinalysis macro (dipstick) panel - Urine

696

2.16

3.52

3.5

4.4

—

(3023368) Bacteria identified in Blood by Culture

272

2.03

3.33

4.4

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.86

3.28

1.6

1.8

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.58

2.87

2.8

2.4

183.59

175.07

ng/l

0.03

(3019198) Lymphocytes [#/volume] in Blood

542

1.78

2.52

6.9

5.8

1.79

1.83

e9/l

0.16

483

(40760892) CBC W Ordered Manual Differential panel - Blood

504

1.77

2.51

7.5

6.5

—

(3044889) 12 lead EKG panel

740

1.86

2.41

4.4

3.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

631

1.75

2.29

8.3

9.6

3.99

4.11

e9/l

0.18

555

(3001604) Monocytes [#/volume] in Blood

532

1.73

2.29

7.0

5.7

0.56

0.58

e9/l

0.37

468

(3006315) Basophils [#/volume] in Blood

532

1.73

2.29

7.0

5.7

0.04

e9/l

0.86

466

(3012544) pH of Venous blood

110

2.09

2.22

2.4

5.0

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

115

1039

2.47

2.22

19.4

14.2

20.41

22.12

mg/l

0.30

105

820

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

3.84

2.18

4.6

4.1

56.86

63.00

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

3.84

2.18

4.6

3.3

3.88

5.34

e9/l

—

(3013115) Eosinophils [#/volume] in Blood

547

1.70

2.17

7.2

5.9

0.16

0.19

e9/l

0.76

484

(3002032) Base excess in Venous blood by calculation

104

2.10

2.15

2.4

5.2

1.36

2.06

mmol/l

0.53

(40768804) Tissue Pathology biopsy report

437

1.67

2.06

2.4

2.0

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

233

1.77

2.05

2.7

2.0

2.74

3.17

mg/l

0.50

206

(3021788) Differential panel - Synovial fluid

3.88

1.96

1.0

1.2

—

(3013707) Erythrocyte sedimentation rate by Westergren method

788

1.72

1.84

5.2

4.1

12.07

11.92

mm/h

0.04

715

(3045142) Bone marrow Pathology biopsy report

3.96

1.73

1.0

1.2

—

(3021589) Normoblasts [#/volume] in Blood

471

1.58

1.72

11.0

9.6

0.00

e9/l

0.49

387

(3020564) Creatinine [Moles/volume] in Serum or Plasma

118

1098

2.54

1.65

21.9

16.8

74.35

77.54

umol/l

0.82

118

1098

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

3.67

1.63

3.2

2.1

2.42

2.62

u/ml

—

(3007853) Bacteria identified in Skin by Aerobe culture

117

1.85

1.56

2.0

1.8

—

(3044941) Cell count panel - Synovial fluid

3.43

1.54

1.0

1.1

—

(40760888) Immunoglobulin light chains.free panel - Serum

2.81

1.45

5.8

7.5

—

(3028626) Oxygen [Partial pressure] in Capillary blood

2.69

1.38

1.7

4.9

9.80

8.10

kpa

—

(3000494) Fungus identified in Specimen by Culture

130

1.74

1.38

1.9

1.4

—

(4034850) Laboratory test

0.00

1.36

0.0

8.1

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

108

980

1.79

1.36

4.7

1.72

1.90

mu/l

1.11

101

884

(3018095) Leukocytes [#/volume] in Urine

385

1.50

1.35

3.2

3.6

10.85

82.49

e6/l

1.78

267

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

164

1.66

1.34

1.9

1.8

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

111

1019

1.85

1.28

4.6

4.7

6.11

5.96

mmol/l

0.40

102

926

(40758558) Short blood count panel - Blood

279

1.52

1.28

6.7

7.2

—

(3019060) Gas panel - Arterial blood

2.02

1.21

4.0

4.1

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.41

1.14

1.6

1.2

—

(4200892) Spirometry reversibility

1.77

1.06

1.4

—

(3003694) ABO and Rh group [Type] in Blood

271

1.46

1.06

1.4

1.5

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

789

1.45

1.06

3.9

4.0

14.54

15.00

pmol/l

1.01

716

(3017143) Hepatitis C virus Ab [Presence] in Serum

124

1.63

1.04

1.4

1.6

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.32

1.04

1.0

1.1

—

(40761536) Microorganisms panel - Urine sediment

1.75

1.03

3.1

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.06

1.02

1.3

1.8

—

(3030467) Casts [#/volume] in Urine by Automated count

301

1.43

1.01

2.9

3.1

0.16

0.40

e6/l

1.43

216

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

109

1.65

1.00

2.9

4.8

2.08

10.57

ug/l

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.99

0.0

1.4

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.94

0.95

1.3

1.9

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.20

0.93

1.5

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.12

0.90

1.3

1.2

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

234

1.43

0.90

2.3

1.9

0.84

1.38

mg/l

1.10

186

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.82

0.86

5.4

3.3

3.95

4.59

pmol/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.73

0.81

1.6

1.5

—

(36304419) Bacteria [Presence] in Urine

286

1.36

0.78

3.0

2.9

—

(3002582) Erythrocytes [#/volume] in Urine

333

1.35

0.77

3.1

8.85

232.60

e6/l

0.60

252

(3000475) Leukocytes [#/volume] in Synovial fluid

2.13

0.75

2.4

1.2

42284.00

11331.31

e6/l

—

(3037756) Immunofixation for Serum or Plasma

2.13

0.75

1.6

1.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.57

0.73

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

397

0.74

0.73

3.3

3.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

119

1.50

0.71

2.0

1.8

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.89

0.69

1.2

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

120

1.48

0.69

2.0

1.8

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.63

0.68

3.8

2.9

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

112

1.49

0.67

2.4

3.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

106

998

1.43

0.66

18.2

13.3

83.78

80.98

ml/min/173m2

0.71

819

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

1.69

0.62

4.2

2.5

216.60

203.43

—

(3034770) Mitochondria Ab [Titer] in Serum

1.69

0.62

1.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.60

0.0

1.1

—

(1761868) Lipid panel - Serum or Plasma

377

0.76

0.60

2.8

3.0

—

(40761511) CBC panel - Blood by Automated count

114

1092

1.55

0.59

16.5

13.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.59

0.0

3.0

—

106.17

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.59

0.0

3.0

—

4.00

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.59

0.0

3.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

196

1.35

0.59

1.9

1.6

1184.68

1190.84

nmol/l

0.01

147

(3020891) Body temperature

1.75

0.58

5.7

4.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

178

1.36

0.58

2.3

2.9

4.20

2.59

e6/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.59

0.57

1.0

1.2

—

(3000492) Spirometry study

1.47

0.57

1.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

404

1.26

0.57

2.2

2.0

83.83

95.82

pmol/l

1.15

197

(3003327) Ova and parasites identified in Stool by Light microscopy

1.65

0.56

3.0

1.5

—

(3026782) Osmolality of Urine

216

1.32

0.56

2.4

3.0

481.05

524.64

mosm/kgh2o

0.74

184

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

319

1.28

0.55

3.6

3.1

891.93

1056.15

ng/l

0.24

256

(3023520) Reticulocytes [#/volume] in Blood

1.48

0.55

2.2

2.9

77.33

73.51

e9/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

144

1.38

0.55

1.5

1.6

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.44

0.53

1.6

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.49

0.50

1.4

1.5

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

193

1.30

0.48

2.2

2.7

0.82

0.84

e6/l

0.02

106

(3009542) Hematocrit [Volume Fraction] of Blood

119

1155

1.75

0.47

29.2

21.0

40.07

40.49

0.34

112

1091

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

177

1.30

0.44

1.8

1.6

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.49

0.44

3.1

4.9

23.70

25.13

mmol/l

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.64

0.43

1.2

1.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.59

0.42

1.4

2.1

—

(3026008) Bacteria identified in Urine by Culture

320

1.22

0.41

2.4

3.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

654

1.20

0.41

3.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.41

0.0

1.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.41

0.0

1.7

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.41

0.0

1.1

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

369

1.21

0.40

3.0

3.1

—

(3012516) Albumin [Mass/volume] in Urine

302

1.22

0.40

3.0

3.4

1776.81

52.95

mg/l

0.47

198

(3007164) IgA [Mass/volume] in Serum or Plasma

217

1.25

0.40

2.4

1.5

1.84

2.26

g/l

0.57

133

(3037522) Nuclear Ab [Titer] in Serum

135

1.30

0.37

1.2

1.4

240.00

403.24

titre

—

(3045414) Leukocytes [Presence] in Urine

1.49

0.36

1.0

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

173

1.26

0.36

1.3

1.8

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.35

0.34

1.3

2.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

292

0.82

0.34

2.3

3.5

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

196

0.79

0.33

2.4

2.8

1.10

0.78

ug/l

0.25

127

(3025941) Bacteria identified in Stool by Culture

1.34

0.31

1.1

1.4

—

(3048689) Calprotectin [Mass/mass] in Stool

127

0.77

0.27

2.7

2.2

172.10

99.26

ug/g

—

109

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

172

1.19

0.24

1.4

1.2

134.09

40.58

iu/ml

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.37

0.24

1.6

1.5

—

(21494755) Public health laboratory ask at order entry panel

0.74

0.23

1.1

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.26

0.22

1.0

1.8

—

(3049717) Cytology report of Urine Cyto stain

1.26

0.22

1.6

2.3

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

1.26

0.22

1.8

2.6

0.00

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

1.26

0.22

1.8

2.6

0.00

g/l

—

(40768443) Skin Pathology biopsy report

1.26

0.22

1.0

1.3

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

1.20

0.21

1.8

2.5

0.00

g/l

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.21

0.0

1.3

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

1.95

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.3

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.4

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

417

1.12

0.21

3.8

3.7

29.93

45.80

ng/l

0.42

302

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.20

0.0

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.20

0.0

1.4

—

(4146454) Self-monitoring of blood glucose

0.00

0.20

0.0

3.0

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.20

0.0

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.20

0.0

1.4

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.16

0.19

3.3

2.2

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

157

1.17

0.18

1.2

0.76

8.18

u/ml

—

(3035350) Ketones [Presence] in Urine by Test strip

519

0.91

0.17

2.7

3.6

0.00

estimate

-0.00

(3020682) Albumin/Creatinine [Ratio] in Urine

324

1.11

0.16

3.0

3.8

1.24

7.84

mg/mmol

3.18

203

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

106

0.84

0.13

1.4

1.8

—

(36660697) Celiac disease serology panel - Serum

1.19

0.13

1.0

1.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

517

1.08

0.12

3.4

5.2

0.00

estimate

-0.00

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

105

1032

1.11

0.11

4.4

4.6

1.41

1.47

mmol/l

0.71

942

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

1.09

0.09

3.4

1.7

231.60

353.20

ug/l

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.10

0.09

5.0

4.9

39.70

48.93

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.08

0.09

3.0

2.3

32.00

43.38

u/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

101

994

1.09

0.09

3.9

4.1

1.26

1.29

mmol/l

0.16

902

(3022145) Colonoscopy Study observation

127

1.12

0.08

1.3

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.06

0.08

1.9

1.2

211.57

133.25

u/ml

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.03

0.08

1.7

4.8

4.91

5.00

kpa

—

(40761535) Cells panel - Urine sediment

1.03

0.07

1.4

3.0

—

(3022621) pH of Urine by Test strip

1.03

0.07

1.6

2.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

236

1.07

0.07

2.8

3.3

—

(3042936) Bacteria identified in Isolate by Culture

149

0.93

0.03

3.4

2.1

—

(40768797) Stomach Pathology biopsy report

151

1.07

0.03

1.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.08

0.02

1.5

1.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

147

0.95

0.01

1.2

1.5

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

105

1057

0.96

0.01

5.3

5.2

2.70

2.73

mmol/l

0.12

963

(3029937) Albumin [Presence] in Urine by Test strip

266

0.97

0.00

3.5

0.00

estimate

-0.00

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

131

0.99

0.00

12.1

7.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

104

1039

1.01

0.00

4.5

4.6

4.56

4.64

mmol/l

0.28

955

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

261

1.00

0.00

4.4

25.00

22.48

—

128

(3013512) EKG study

325

0.98

0.00

3.1

4.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.02

0.00

1.4

1.7

—

(3009261) Glucose [Presence] in Urine by Test strip

524

0.99

0.00

2.6

3.6

0.00

estimate

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.00

0.00

1.4

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.6

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

-0.00

0.0

1.0

—

147.33

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

59.57

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.3

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

-0.00

0.0

1.3

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

3.2

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

-0.00

0.0

9.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.3

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

0.30

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

1.50

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

7.4

—

0.64

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.3

—

33.33

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.3

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

1.5

—

2165.83

—

(3017732) Neutrophils [#/volume] in Blood

0.97

-0.00

2.0

2.2

3.37

4.71

e9/l

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

1.7

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.8

—

1.20

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.7

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.4

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.8

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.8

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.95

-0.00

1.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.3

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.3

—

135.20

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.4

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.6

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.7

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

-0.00

0.0

1.4

—

14.00

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

5.45

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

5.4

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.1

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

15.4

—

1399.88

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.4

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

13.3

—

810.38

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.5

—

8.50

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.4

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3019225) pH of Specimen

100

1.00

-0.00

3.5

5.5

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

13.20

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_MEDIASTINUM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MEDIASTINUM.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MEDIASTINUM – Benign neoplasm: Mediastinum

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Mediastinum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints