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Benign neoplasm of other and unspecified intrathoracic organs

DOID Endpoint Browser PheWeb

CD2_BENIGN_INTRATHORACIC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D15
  • Cause of death: ICD-10 — D15

2 out of 7 registries used, show all original rules.

343

4. Check minimum number of events

None

343

5. Include endpoints

396

6. Filter based on genotype QC (FinnGen only)

375

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum endothoracicorum aliorum sive non specificatorum

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2498 1388 1085
Only index persons 2049 1198 851
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population 54.47 56.23 51.98
Only index persons 52.89 55.50 49.23

-FinnGen-

Key figures

All Female Male
Number of individuals 375 205 170
Unadjusted period prevalence (%) 0.08 0.07 0.08
Median age at first event (years) 57.76 57.48 58.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
396
Matched controls
3960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.1
ICD-10 Finland
Benign neoplasm: Heart
+∞
133.0
120
*
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
100.4
92
*
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
86.7
80
*
FFA10
NOMESCO Finland
Excision of lesion of atrium
+∞
74.4
69
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
230.3
58.8
59
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.2
51.7
108
227
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
51.5
149
417
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
477.6
44.1
43
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.9
43.6
75
129
D15.9
ICD-10 Finland
Benign neoplasm: Intrathoracic organ, unspecified
+∞
42.5
40
*
D15.7
ICD-10 Finland
Benign neoplasm: Other specified intrathoracic organs
+∞
39.2
37
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
8.2
37.8
54
75
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
32.8
262
1393
GEB30
NOMESCO Finland
Mediastinotomy and excision of lesion
277.8
26.0
26
*
21250
ICD-8 Finland
Benign neoplasm of respiratory system, Mediastinum
+∞
24.2
23
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
22.6
151
686
GEC23
NOMESCO Finland
Transsternal thymectomy
232.3
21.8
22
*
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
232.3
21.8
22
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.8
21.3
52
121
WX872
NOMESCO Finland
Intensive care
5.1
20.9
47
102
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
17.6
110
474
8582/3-C37.9
ICD-O-3
Thymoma, type AB of thymus
+∞
16.8
16
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
15.6
186
1078
R4110
NOMESCO Finland
Physiotherapy
2.5
15.6
146
761
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
24.5
15.3
21
9
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.5
14.8
124
612
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
13.6
13
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.4
13.2
51
165
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
12.9
42
121
GD1AD
NOMESCO Finland
Thorax CT examination
3.8
12.9
42
121
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
12.6
12
*
ZXC96
NOMESCO Finland
Robot assisted procedure
5.6
12.0
23
43
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
48.2
12.0
14
*
B01AB05
ATC
enoxaparin; parenteral
2.2
11.9
152
884
AJX
HP
Other surgery on the heart or aorta
67.0
11.7
13
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
11.5
11
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
11.2
57
217
WX402
NOMESCO Finland
General anaesthesia
2.3
10.8
99
500
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.6
10.7
36
106
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
10.6
45
154
2125A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Mediastinum
+∞
10.5
10
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
5.0
10.1
22
46
G70.0
ICD-10 Finland
Myasthenia gravis
26.8
9.9
13
5
B01AB04
ATC
dalteparin; parenteral
3.7
9.7
32
93
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
9.5
117
662
N07AA02
ATC
pyridostigmine; systemic
18.1
9.5
14
8
AMX
HP
Other surgical procedure for a demanding cardiac patient
102.4
9.5
10
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
9.3
60
257
C03CA01
ATC
furosemide; systemic
2.0
9.2
138
837
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.5
9.1
32
97
N02AX02
ATC
tramadol; systemic, rectal
1.9
8.8
188
1279
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
8.8
97
524
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.5
8.5
30
91
R06.0
ICD-10 Finland
Dyspnoea
2.0
8.5
122
725
GAA31
NOMESCO Finland
Thoracoscopy
91.9
8.4
9
*
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
91.9
8.4
9
*
WZC30
NOMESCO Finland
Teaching
2.2
8.1
77
391
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.8
128
792
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.1
7.7
21
53
108
Kela drug reimbursment
Myasthenia gravis
25.6
7.6
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
7.3
154
1028
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.2
7.2
19
47
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
7.0
68
348
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
40.8
6.8
8
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.1
6.7
28
95
B01AA03
ATC
warfarin; systemic
2.0
6.6
83
466
S29
ICPC
Skin symptom/complaint other
2.0
6.6
79
437
ZXE00
NOMESCO Finland
One hour or less
1.8
6.6
156
1071
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
7.6
6.5
14
19
AN1
HP
Coronary angiography
2.3
6.5
52
246
51
HP
Other heart surgery
70.9
6.4
7
*
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
70.9
6.4
7
*
A02BC02
ATC
pantoprazole; systemic
1.8
6.3
271
2184
I31.8
ICD-10 Finland
Other specified diseases of pericardium
+∞
6.3
6
*
21240
ICD-8 Finland
Benign neoplasm of respiratory system, Pleura
+∞
6.3
6
*
2129X
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Site unspecified
+∞
6.3
6
*
I51.3
ICD-10 Finland
Intracardiac thrombosis, not elsewhere classified
+∞
6.3
6
*
GEA00
NOMESCO Finland
Mediastinoscopy
27.1
6.2
8
*
R81
ICPC
Pneumonia
3.6
6.2
20
57

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
267
1572
3.14
25.52
16.0
12.9
1.24
1.23
inr
0.07
57
455
164
802
2.78
21.10
2.3
2.2
—
—
—
0
0
259
1626
2.71
19.73
8.3
6.6
1.20
1.21
mmol/l
2.67
228
1395
249
1543
2.65
19.31
2.6
2.5
—
—
—
0
0
193
1061
2.60
19.20
2.5
2.3
—
—
—
0
0
237
1486
2.48
17.13
9.7
5.7
1.20
1.21
mmol/l
2.80
224
1345
83
317
3.05
16.42
11.1
7.7
118.77
120.60
g/l
0.37
83
311
93
384
2.86
15.96
10.7
7.0
1.21
1.00
mmol/l
0.21
83
306
93
387
2.83
15.71
10.7
6.9
5.40
5.07
kpa
2.31
93
369
93
387
2.83
15.71
10.7
6.9
12.85
12.05
kpa
0.73
93
370
80
308
3.00
15.56
1.4
1.4
—
—
—
0
0
55
172
3.55
15.01
11.2
8.5
—
—
—
0
0
276
1938
2.40
14.30
7.7
4.5
6.61
6.71
mmol/l
0.38
268
1813
62
217
3.20
14.14
12.5
8.4
0.66
0.69
%
0.24
62
212
62
218
3.19
14.02
12.3
8.2
1.21
1.44
%
1.23
62
213
72
278
2.94
13.85
10.4
7.8
—
—
—
0
0
326
2550
2.58
11.99
9.1
7.5
80.72
78.57
u/l
0.49
317
2389
151
887
2.14
11.42
4.7
4.1
—
—
—
0
0
210
1399
2.07
11.30
5.6
4.7
35.64
35.63
g/l
0.01
193
1320
89
428
2.39
10.87
1.3
1.3
—
—
—
0
0
137
789
2.13
10.80
2.9
2.0
3.28
3.20
mg/l
0.13
119
677
220
1514
2.02
10.57
7.2
6.1
8.81
8.66
%
0.28
212
1427
161
993
2.05
10.50
4.7
3.9
7.41
7.40
ph
0.75
26
180
223
1546
2.01
10.44
7.1
6.0
26.16
27.73
%
1.41
215
1453
48
174
3.00
10.23
11.4
9.2
24.31
24.44
mmol/l
0.12
48
169
160
998
2.01
10.01
3.7
3.2
882.15
1332.70
ng/l
1.96
144
830
219
1525
1.98
9.95
7.4
6.3
—
—
—
0
0
217
1508
1.97
9.90
7.0
5.8
2.60
2.86
%
1.09
209
1414
232
1650
1.98
9.89
6.8
5.7
1.74
1.97
e9/l
1.58
199
1463
228
1617
1.97
9.74
6.8
5.6
0.59
0.58
e9/l
0.24
190
1403
233
1669
1.96
9.62
7.3
6.0
0.16
0.19
e9/l
2.53
196
1464
217
1523
1.94
9.46
6.9
5.7
59.27
57.03
%
2.14
210
1434
227
1620
1.94
9.38
6.8
5.6
0.04
0.04
e9/l
0.44
189
1406
210
1462
1.93
9.34
7.1
5.8
0.66
0.68
%
0.16
202
1367
253
1886
1.95
9.03
10.7
9.4
4.08
4.09
e9/l
0.01
211
1661
189
1310
1.85
8.16
2.2
2.1
—
—
—
0
0
108
642
1.94
7.39
4.0
3.9
361.50
291.38
ng/l
0.15
90
511
298
2423
1.93
7.32
5.0
4.1
14.75
12.01
mm/h
1.73
281
2222
151
1008
1.80
7.14
2.4
2.1
197.05
211.28
u/l
0.17
146
946
188
1346
1.76
6.94
3.3
2.7
134.49
129.91
ug/l
0.09
174
1234
48
223
2.31
6.22
8.5
4.6
—
—
—
0
0
61
314
2.11
6.16
5.2
3.7
2.38
1.97
mmol/l
0.39
52
250
78
440
1.96
6.13
3.0
2.3
19.75
22.81
%
1.43
71
380
52
252
2.22
6.10
1.4
1.4
—
—
—
0
0
156
1096
1.70
5.92
3.8
3.4
2.35
2.35
mmol/l
0.28
140
972
226
1758
1.67
5.75
7.8
6.4
11.51
11.22
umol/l
0.19
215
1667
45
211
2.28
5.71
15.2
6.9
25.94
24.31
mmol/l
2.15
45
199
193
1444
1.66
5.70
12.7
9.3
0.00
0.00
e9/l
0.05
151
1187
17
47
3.73
5.54
2.5
2.9
—
—
—
0
0
280
2316
1.71
5.53
4.9
3.9
—
—
—
0
0
122
816
1.72
5.47
7.9
7.3
—
—
—
0
0
270
2237
1.65
5.04
4.7
4.3
—
—
—
0
0
159
1161
1.62
5.00
4.0
3.6
133.32
86.35
e6/l
0.26
113
838
20
69
3.00
4.67
2.8
5.4
—
—
—
0
0
105
709
1.65
4.43
2.5
1.7
1.25
1.20
mg/l
0.06
89
561
172
1316
1.54
4.25
2.6
2.2
78.37
78.19
nmol/l
0.03
155
1159
129
925
1.59
4.24
3.6
3.0
0.42
0.52
e6/l
0.26
97
699
48
261
1.95
4.17
3.3
2.8
10.48
10.32
g/l
0.05
42
241
41
211
2.05
4.15
2.1
1.6
0.94
1.33
g/l
1.33
32
194
82
528
1.70
4.12
2.9
2.8
4.06
1.97
e6/l
0.77
41
295
354
3224
1.92
3.99
22.6
14.3
23.19
23.15
mg/l
0.01
323
2550
50
284
1.87
3.82
2.8
2.6
77.69
69.54
e9/l
0.71
30
224
135
998
1.54
3.81
3.7
3.1
—
—
—
0
0
7
8
8.88
3.78
1.9
1.8
—
—
—
0
0
6
5
12.15
3.77
11.7
7.4
—
—
—
0
0
136
1009
1.53
3.77
3.7
3.1
22.37
120.83
e6/l
0.89
102
780
166
1292
1.49
3.63
5.2
3.7
46.99
38.79
ng/l
0.36
116
931
330
2971
1.66
3.53
4.8
4.6
1.91
1.92
mu/l
0.03
307
2686
121
890
1.52
3.45
3.7
2.9
—
—
—
0
0
39
214
1.91
3.32
2.4
2.9
—
—
—
0
0
7
11
6.45
3.19
1.3
1.5
56.86
57.36
nmol/24h
—
7
11
72
478
1.62
3.19
1.6
1.7
—
—
—
0
0
22
98
2.32
3.19
3.1
4.5
169.54
117.58
mg/l
0.21
16
80
22
98
2.32
3.19
3.1
4.5
20.59
35.38
mg/l
1.76
17
81
50
303
1.74
3.11
2.7
2.1
0.20
0.22
g/l
0.92
45
285
59
375
1.67
3.09
3.1
4.2
4.04
45.54
ug/l
1.22
45
316
17
68
2.57
3.08
2.2
2.3
128.63
127.98
g/l
—
8
47
11
31
3.62
3.01
2.1
2.0
1.26
1.11
e9/l
0.20
11
26
165
1319
1.43
3.00
2.0
1.9
92.67
96.27
pmol/l
0.48
97
682
94
674
1.52
2.98
3.0
3.0
537.02
547.41
mosm/kgh2o
0.19
81
575
23
110
2.16
2.84
10.8
3.8
3.87
3.99
mmol/l
0.53
23
105
14
53
2.70
2.82
1.1
1.4
—
—
—
0
0
50
313
1.68
2.78
1.5
1.4
—
—
—
0
0
26
132
2.04
2.77
9.9
3.5
1.25
1.38
mmol/l
0.36
26
124
26
132
2.04
2.77
2.0
1.9
1.75
1.46
g/l
0.52
20
115
65
436
1.59
2.76
1.5
1.4
382.00
501.67
titre
0.49
20
96
86
615
1.51
2.75
2.9
3.0
2.47
2.45
mmol/l
0.39
75
542
14
54
2.65
2.73
3.7
3.6
—
—
—
0
0
14
55
2.60
2.64
4.4
3.3
59.00
57.44
%
0.15
14
55
52
334
1.64
2.63
1.5
1.5
—
—
—
0
0
16
68
2.41
2.59
3.1
2.3
—
—
—
0
0
112
857
1.43
2.52
3.2
2.8
337.19
7112.30
umol/l
3.54
103
755
111
848
1.43
2.52
1.4
1.4
—
—
—
0
0
94
696
1.46
2.52
3.0
2.5
4.16
4.90
e6/l
0.53
84
625
56
371
1.59
2.51
3.0
2.9
7.82
9.39
umol/l
0.22
48
330
11
37
3.03
2.50
1.8
1.6
23.49
18.12
ug/l
0.19
11
37
15
63
2.44
2.49
4.5
3.1
—
—
—
0
0
7
16
4.43
2.48
1.3
1.1
—
—
—
0
0
8
21
3.87
2.47
4.5
4.0
91.38
93.62
nmol/l
—
8
21
13
52
2.55
2.38
4.6
2.9
4.20
4.74
e9/l
0.39
13
52
16
71
2.31
2.37
8.9
6.6
106.19
104.94
mmol/l
0.59
16
65
16
71
2.31
2.37
8.9
6.6
10.19
10.97
mmol/l
0.55
16
65
11
39
2.87
2.36
2.9
3.0
—
—
—
0
0
24
127
1.95
2.31
1.3
1.2
—
—
—
0
0
77
558
1.47
2.30
1.2
1.3
114.82
40.42
iu/ml
0.76
20
184
10
34
2.99
2.29
1.8
1.7
—
—
—
0
0
10
34
2.99
2.29
1.1
1.0
—
—
—
0
0
11
40
2.80
2.29
2.0
1.4
36.57
31.42
g/l
0.79
11
35
11
41
2.73
2.22
5.5
3.2
2.98
7.44
nmol/l
0.59
11
41
8
24
3.38
2.19
2.4
2.2
27.57
36.67
%
—
8
24
363
3435
1.68
2.18
25.7
16.9
78.48
77.11
umol/l
0.29
363
3435
53
359
1.55
2.17
1.9
1.6
—
—
—
0
0
19
95
2.05
2.14
1.5
1.4
252.23
306.01
ug/g
0.45
13
57
32
191
1.73
2.14
1.4
1.2
112.28
198.41
u/ml
0.72
26
171
27
154
1.81
2.10
4.1
3.8
—
—
—
0
0
271
2436
1.36
2.10
3.7
3.8
14.86
14.90
pmol/l
0.09
247
2178
86
648
1.42
2.09
1.7
1.5
2.53
2.53
g/l
0.00
51
392
24
132
1.87
2.09
14.8
4.3
—
—
—
0
0
20
104
1.97
2.04
2.7
3.3
0.29
0.20
g/l
—
10
43
10
38
2.67
2.02
1.9
1.3
—
—
—
0
0
364
3458
1.65
2.00
13.6
10.6
24.96
26.27
u/l
1.02
357
3332
59
417
1.49
2.00
1.5
1.3
—
—
—
0
0
14
64
2.23
1.96
1.6
1.7
—
—
—
0
0
63
454
1.46
1.94
1.3
1.2
—
—
—
0
0
14
65
2.20
1.90
1.4
2.0
—
—
—
0
0
66
482
1.44
1.90
2.2
1.9
—
—
—
0
0
24
137
1.80
1.88
7.9
4.6
0.91
0.89
%
0.08
24
131
24
137
1.80
1.88
7.9
4.6
1.86
1.48
%
0.81
24
130
95
741
1.37
1.88
3.7
3.7
—
—
—
0
0
9
34
2.68
1.87
2.0
1.3
—
—
—
0
0
45
307
1.53
1.81
2.4
2.5
34.42
32.95
u/l
0.14
38
258
16
81
2.02
1.77
1.6
1.5
26898.10
18998.49
e6/l
—
10
59
55
394
1.46
1.75
1.4
1.5
—
—
—
0
0
5
13
3.88
1.72
1.6
1.8
56.40
58.87
ug/l
—
5
13
70
527
1.40
1.71
1.2
1.3
14.07
11.33
u/ml
0.12
21
209
10
40
2.54
1.67
2.0
1.4
0.63
0.53
nmol/l
—
10
35
236
2118
1.28
1.64
3.9
3.1
51.63
49.40
u/l
0.11
227
1973
10
43
2.36
1.60
1.1
1.2
—
—
—
0
0
7
26
2.72
1.58
2.4
2.0
595.29
507.75
e6/l
—
7
20
334
3151
1.38
1.55
4.8
4.6
5.94
5.98
mmol/l
0.23
305
2872
7
27
2.62
1.52
1.1
1.2
—
—
—
0
0
12
58
2.10
1.50
1.8
1.8
73.54
63.32
%
0.84
12
58
95
767
1.31
1.48
1.7
1.5
19.30
21.12
nmol/l
0.78
88
647
13
67
1.97
1.40
3.7
3.2
29.00
32.32
umol/l
0.33
13
59
77
611
1.32
1.36
1.9
1.7
1132.81
1195.60
nmol/l
0.27
60
461
31
210
1.52
1.32
1.1
1.4
—
—
—
0
0
8
34
2.38
1.30
1.1
1.1
—
—
—
0
0
5
18
2.80
1.29
1.2
1.8
—
—
—
0
0
5
18
2.80
1.29
12.4
13.6
1065.60
863.44
nmol/l
—
5
18
5
18
2.80
1.29
15.0
18.3
1518.00
1448.78
nmol/l
—
5
18
8
35
2.31
1.27
3.4
1.4
—
—
—
0
0
8
35
2.31
1.27
2.1
1.2
—
—
—
0
0
6
26
2.33
1.19
1.8
2.1
—
—
—
0
0
180
1605
1.22
1.19
5.2
5.2
0.00
0.00
estimate
0.50
39
309
15
87
1.75
1.16
1.1
1.2
—
—
—
0
0
5
20
2.52
1.15
3.4
1.4
0.84
0.99
g/l
—
5
20
123
1058
1.24
1.14
2.6
2.4
55.33
61.04
u/l
0.59
109
978
11
58
1.92
1.13
1.0
1.8
—
—
—
0
0
11
58
1.92
1.13
1.2
1.1
—
—
—
0
0
350
3363
1.35
1.12
20.2
13.4
—
—
—
0
0
14
81
1.76
1.10
1.9
1.3
—
2.91
—
0
15
319
3031
1.27
1.09
5.6
5.9
39.11
40.09
mmol/mol
1.46
298
2811
10
52
1.95
1.07
1.2
1.4
—
—
—
0
0
15
90
1.69
1.05
1.4
1.2
—
51.43
—
0
7
180
1623
1.20
1.02
3.9
3.8
0.00
0.00
estimate
-0.00
36
300
31
224
1.42
1.00
3.4
2.4
4.40
5.21
e9/l
0.29
31
179
29
207
1.43
1.00
1.0
1.3
—
—
—
0
0
7
36
1.96
0.97
2.1
1.4
—
—
nmol/l
—
0
0
38
287
1.36
0.96
4.2
4.2
1.35
0.88
%
0.50
13
111
9
51
1.78
0.95
1.3
1.0
—
—
—
0
0
10
55
1.84
0.93
3.8
2.3
—
—
—
0
0
142
1264
1.19
0.91
3.5
3.6
5.79
5.94
ph
—
7
102
114
999
1.20
0.86
5.1
3.9
—
—
—
0
0
8
44
1.83
0.86
1.0
1.1
—
—
—
0
0
8
44
1.83
0.86
1.0
1.1
—
—
—
0
0
35
267
1.34
0.84
4.1
4.3
0.30
0.14
%
—
10
91
98
1119
0.83
0.81
3.1
3.0
—
—
—
0
0
8
47
1.72
0.81
1.1
1.2
—
—
—
0
0
20
280
0.70
0.80
1.3
1.4
—
—
—
0
0
33
252
1.34
0.80
4.4
4.3
0.13
0.15
%
—
8
75
19
132
1.46
0.77
1.8
2.7
—
—
—
0
0
174
1597
1.16
0.75
4.0
3.8
0.00
0.00
estimate
0.50
39
331
30
229
1.34
0.73
2.2
2.0
15.53
13.40
nmol/l
0.60
21
210
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
13
84
1.57
0.72
1.2
1.4
—
—
—
0
0
9
59
1.54
0.69
1.3
1.5
—
—
—
0
0
5
27
1.86
0.68
1.4
1.2
0.06
0.38
u/ml
—
5
14
110
983
1.16
0.66
3.3
3.3
1128.44
185.11
mg/l
0.64
78
639
5
28
1.80
0.66
1.0
1.2
—
—
—
0
0
7
44
1.60
0.65
1.3
2.2
—
—
—
0
0
25
190
1.34
0.64
1.1
1.3
—
—
—
0
0
75
651
1.19
0.64
1.8
1.8
404.60
444.65
pmol/l
0.88
62
533
115
1035
1.16
0.63
3.3
3.1
8.26
7.50
mmol/l
0.91
107
867
98
872
1.16
0.62
1.5
1.7
1.31
1.37
mmol/l
0.41
86
734
10
63
1.60
0.62
2.1
1.8
5.26
4.49
mmol/24h
—
10
53
366
3585
1.28
0.60
33.1
21.0
6.78
6.72
e9/l
0.26
361
3478
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
366
3586
1.27
0.59
33.9
21.1
39.52
40.30
%
1.99
343
3357
366
3586
1.27
0.59
33.0
21.0
4.42
4.50
e12/l
2.13
360
3478
10
64
1.58
0.59
1.4
1.2
—
—
—
0
0
40
329
1.24
0.59
1.5
1.6
—
—
—
0
0
6
35
1.73
0.58
1.2
1.1
—
—
—
0
0
114
1036
1.14
0.55
3.8
3.8
8.73
9.05
mg/mmol
0.03
78
653
6
39
1.55
0.53
1.0
1.2
—
—
—
0
0
6
39
1.55
0.53
3.7
1.8
89.88
89.42
%
—
6
39
10
66
1.53
0.53
1.3
1.1
—
—
—
0
0
6
40
1.51
0.52
1.2
1.3
—
—
—
0
0
80
714
1.15
0.50
1.3
1.3
0.92
1.33
u/ml
0.59
22
200
7
109
0.64
0.49
17.9
11.0
—
—
—
0
0
14
102
1.39
0.48
1.0
1.3
—
—
—
0
0
82
903
0.88
0.43
3.9
3.5
—
—
—
0
0
5
32
1.57
0.42
2.6
2.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
17
132
1.30
0.41
1.6
1.8
—
—
—
0
0
5
34
1.48
0.40
1.2
3.4
—
—
—
0
0
21
258
0.80
0.39
1.3
1.5
—
—
—
0
0
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
36
310
1.18
0.37
4.0
4.2
—
—
—
0
0
6
41
1.47
0.36
1.2
1.9
22.33
32.51
pg
—
6
41
6
42
1.44
0.35
1.2
1.2
—
—
—
0
0
16
200
0.79
0.35
1.8
1.7
—
—
—
0
0
14
178
0.78
0.35
2.9
2.6
—
—
—
0
0
6
44
1.37
0.34
23.7
7.4
8.00
6.67
mmol/l
—
6
35
6
44
1.37
0.34
1.2
1.3
—
—
—
0
0
57
630
0.89
0.32
3.1
3.0
1.35
0.80
ug/l
0.91
42
412
32
277
1.17
0.32
5.5
3.6
—
—
—
0
0
30
259
1.17
0.31
4.0
4.1
0.89
0.50
%
—
9
89
28
243
1.16
0.27
1.1
1.2
—
—
—
0
0
115
1089
1.08
0.26
4.6
4.8
2.32
2.65
ug/l
0.27
105
973
15
180
0.83
0.24
1.1
1.5
—
—
—
0
0
65
700
0.91
0.24
4.4
4.1
1.01
1.02
kg/l
—
10
106
43
391
1.11
0.23
2.3
2.2
124.82
126.22
ug/g
0.02
38
324
31
276
1.13
0.23
4.5
3.5
—
—
—
0
0
5
40
1.25
0.22
1.8
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
133.00
—
0
14
13
109
1.20
0.19
1.5
1.6
—
—
—
0
0
5
69
0.72
0.17
1.6
1.3
3.86
3.85
mmol/l
—
5
63
12
102
1.18
0.15
3.1
5.2
—
—
—
0
0
9
82
1.10
0.15
2.4
2.3
—
—
—
0
0
7
88
0.79
0.14
1.1
1.4
—
—
—
0
0
10
84
1.20
0.14
1.1
1.1
—
—
—
0
0
11
128
0.86
0.13
1.1
1.1
—
—
—
0
0
322
3191
1.05
0.11
4.5
4.5
1.42
1.47
mmol/l
1.32
300
2925
16
177
0.90
0.10
3.2
2.8
0.16
0.13
e6/l
0.08
16
171
5
47
1.06
0.09
1.0
1.1
—
25.00
—
0
11
330
3276
1.04
0.09
5.2
5.1
2.59
2.74
mmol/l
2.13
305
2998
311
3085
1.04
0.09
4.1
4.0
1.25
1.28
mmol/l
0.48
290
2810
12
133
0.90
0.08
1.5
1.6
—
—
—
0
0
19
176
1.08
0.07
3.3
4.1
—
—
—
0
0
7
81
0.86
0.07
1.1
1.4
—
—
—
0
0
9
104
0.86
0.06
2.9
2.9
—
—
—
0
0
39
376
1.04
0.05
1.5
1.3
—
—
—
0
0
89
876
1.02
0.04
4.9
3.9
0.00
0.01
estimate
0.80
36
300
15
143
1.05
0.01
1.0
1.1
—
—
—
0
0
21
213
0.99
0.00
2.9
2.9
—
—
—
0
0
321
3206
1.01
0.00
4.6
4.6
4.47
4.64
mmol/l
2.06
298
2957
11
114
0.96
0.00
1.0
1.1
—
—
—
0
0
5
56
0.89
0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
-0.00
1.1
1.3
—
—
—
0
0
8
89
0.90
-0.00
1.1
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
38.20
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.03
—
0
5
8
88
0.91
-0.00
1.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.4
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
3.2
3.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
4.18
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
6.42
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_INTRATHORACIC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_INTRATHORACIC 1.723 [1.35, 2.2] < 0.001
Birth year 0.99 [0.98, 1.0] 0.024

During the follow-up period (1.1.1998 — 31.12.2019), 170 out of 792 females with CD2_BENIGN_INTRATHORACIC died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_INTRATHORACIC 1.914 [1.5, 2.44] < 0.001
Birth year 0.988 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 144 out of 631 males with CD2_BENIGN_INTRATHORACIC died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_INTRATHORACIC.

N-year risk Females Males
1 0.14% 0.406%
5 0.988% 2.501%
10 2.339% 6.167%
15 4.24% 11.267%
20 7.286% 18.197%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_INTRATHORACIC – Benign neoplasm of other and unspecified intrathoracic organs

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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