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Benign neoplasm of other and unspecified intrathoracic organs

DOID Endpoint Browser PheWeb

CD2_BENIGN_INTRATHORACIC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D15
  • Cause of death: ICD-10 — D15

2 out of 7 registries used, show all original rules.

328

4. Check minimum number of events

None

328

5. Include endpoints

381

6. Filter based on genotype QC (FinnGen only)

381

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum endothoracicorum aliorum sive non specificatorum

Similar endpoints

↥

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2498 1388 1085
Only index persons 2049 1198 851
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population 54.47 56.23 51.98
Only index persons 52.89 55.50 49.23

-FinnGen-

Key figures

All Female Male
Number of individuals 381 208 173
Unadjusted period prevalence (%) 0.07 0.07 0.08
Median age at first event (years) 56.40 55.68 57.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
340
Matched controls
3398
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.1
ICD-10 Finland
Benign neoplasm: Heart
+∞
115.3
104
*
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
82.8
76
*
FFA10
NOMESCO Finland
Excision of lesion of atrium
+∞
66.9
62
*
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
64.7
60
*
D15.9
ICD-10 Finland
Benign neoplasm: Intrathoracic organ, unspecified
+∞
41.5
39
*
D15.7
ICD-10 Finland
Benign neoplasm: Other specified intrathoracic organs
+∞
35.0
33
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
73.1
34.8
39
6
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
182.1
32.3
33
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.8
31.9
88
166
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
8.0
26.5
63
94
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.4
26.0
110
332
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
25.0
208
1085
GEB30
NOMESCO Finland
Mediastinotomy and excision of lesion
+∞
23.2
22
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
8.9
20.8
45
57
21250
ICD-8 Finland
Benign neoplasm of respiratory system, Mediastinum
+∞
20.0
19
*
GEC23
NOMESCO Finland
Transsternal thymectomy
200.6
18.7
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
18.1
135
609
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
+∞
17.9
17
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.2
14.3
45
96
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
44.5
14.2
17
*
AJX
HP
Other surgery on the heart or aorta
+∞
13.6
13
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.0
13.3
88
356
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
72.6
12.7
14
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.7
12.4
99
447
R4110
NOMESCO Finland
Physiotherapy
2.5
11.9
118
601
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
11.5
11
*
WX872
NOMESCO Finland
Intensive care
4.7
11.4
39
91
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
10.9
91
420
C37
ICD-10 Finland
Malignant neoplasm of thymus
113.4
10.5
11
*
AMX
HP
Other surgical procedure for a demanding cardiac patient
+∞
10.5
10
*
2125A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Mediastinum
+∞
10.5
10
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
9.9
44
132
GAE06
NOMESCO Finland
Excision of lesion of chest wall
102.8
9.5
10
*
8582/3-C37.9
ICD-O-3
Thymoma, type AB of thymus
+∞
9.4
9
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
9.2
35
92
WZC30
NOMESCO Finland
Teaching
2.8
9.1
63
259
B01AB05
ATC
enoxaparin; parenteral
2.1
8.5
122
715
N07AA02
ATC
pyridostigmine; systemic
22.7
8.1
11
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
8.1
85
435
C03CA01
ATC
furosemide; systemic
2.1
8.0
112
647
G70.0
ICD-10 Finland
Myasthenia gravis
18.9
7.6
11
6
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
7.4
38
128
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
+∞
7.3
7
*
WX402
NOMESCO Finland
General anaesthesia
2.4
7.0
64
304
108
Kela drug reimbursment
Myasthenia gravis
23.0
6.7
9
*
51
HP
Other heart surgery
71.1
6.4
7
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
6.2
6.4
16
27
AN1
HP
Coronary angiography
2.5
6.4
48
207
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
9.5
6.3
12
13
ZXC96
NOMESCO Finland
Robot assisted procedure
5.0
6.3
19
40
2129X
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Site unspecified
+∞
6.3
6
*
GAA31
NOMESCO Finland
Thoracoscopy
27.2
6.3
8
*
GEA00
NOMESCO Finland
Mediastinoscopy
27.2
6.3
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
6.2
104
635
TFP20
NOMESCO Finland
Cardiodefibrillation
3.2
6.2
31
104
N02AX02
ATC
tramadol; systemic, rectal
1.8
6.1
147
1017
XF404
NOMESCO Finland
Ambulatory ECG
2.7
6.0
39
154

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
243
1312
3.35
28.63
8.7
8.4
1.2
1.2
inr
0.02
48
379
159
767
2.84
21.20
2.3
2.2
—
—
—
0
0
250
1564
2.74
19.34
8.4
6.7
1.2
1.2
mmol/l
2.37
222
1336
186
1014
2.63
18.97
2.5
2.3
—
—
—
0
0
237
1471
2.62
18.18
3.8
4.1
—
—
—
0
0
231
1429
2.57
17.65
9.9
5.8
1.2
1.2
mmol/l
2.14
220
1292
86
338
2.99
16.23
11.2
7.5
96.0
95.7
%
0.15
86
325
81
308
3.07
16.19
11.2
7.8
118.5
120.7
g/l
0.43
81
300
89
373
2.81
14.83
11.0
7.1
1.4
1.0
mmol/l
0.41
79
294
89
376
2.78
14.58
11.0
7.0
12.6
12.1
kpa
0.48
89
359
89
376
2.78
14.58
11.0
7.0
5.4
5.1
kpa
2.34
89
358
53
165
3.57
14.58
11.5
8.8
—
—
—
0
0
76
301
2.90
14.01
1.4
1.3
—
—
—
0
0
60
209
3.22
13.81
12.8
8.6
0.7
0.7
%
0.16
60
204
69
267
2.93
13.23
10.7
8.0
—
—
—
0
0
59
210
3.14
13.08
12.7
8.5
1.2
1.5
%
1.31
59
205
263
1865
2.32
12.93
7.9
4.6
6.6
6.7
mmol/l
0.28
252
1741
314
2439
2.63
12.08
9.2
7.6
80.9
78.6
u/l
0.51
303
2282
170
1038
2.15
11.84
6.8
5.7
—
—
—
0
0
159
958
2.13
11.35
4.7
3.9
7.4
7.4
ph
0.73
26
175
146
854
2.15
11.23
4.8
4.2
—
—
—
0
0
133
761
2.15
10.74
2.9
2.0
3.3
3.2
mg/l
0.11
116
654
200
1350
2.01
10.16
5.6
4.8
35.5
35.6
g/l
0.03
183
1271
212
1479
1.98
9.60
7.2
5.9
26.0
27.7
%
1.53
203
1377
209
1452
1.97
9.57
7.4
6.1
8.8
8.7
%
0.26
201
1367
206
1445
1.93
8.96
7.1
5.8
2.6
2.9
%
1.07
195
1348
220
1581
1.93
8.85
6.9
5.7
1.7
2.0
e9/l
1.56
187
1392
206
1457
1.90
8.61
7.0
5.7
59.5
57.1
%
2.35
199
1367
216
1552
1.90
8.60
6.9
5.6
0.6
0.6
e9/l
0.30
178
1341
200
1403
1.90
8.56
7.2
5.8
0.7
0.7
%
0.12
192
1310
221
1603
1.90
8.51
7.5
6.0
0.2
0.2
e9/l
2.13
185
1404
215
1556
1.88
8.23
6.9
5.7
0.0
0.0
e9/l
0.39
178
1345
241
1810
1.90
8.20
10.9
9.5
4.1
4.1
e9/l
0.14
200
1592
149
969
1.88
7.91
2.4
2.1
198.9
215.9
u/l
0.21
144
907
78
411
2.13
7.50
1.3
1.3
—
—
—
0
0
105
620
1.96
7.38
4.0
3.9
365.4
301.5
ng/l
0.13
89
493
179
1260
1.79
7.17
2.2
2.1
—
—
—
0
0
181
1287
1.77
6.93
3.3
2.7
137.6
131.3
ug/l
0.12
168
1176
285
2320
1.91
6.89
5.1
4.1
15.1
12.0
mm/h
1.98
269
2126
48
218
2.38
6.56
8.5
4.6
—
—
—
0
0
120
785
1.77
5.93
7.9
7.4
—
—
—
0
0
58
299
2.11
5.84
5.1
3.8
2.5
2.0
mmol/l
0.46
46
238
218
1684
1.69
5.83
7.9
6.4
11.4
11.3
umol/l
0.08
206
1597
49
237
2.23
5.79
1.4
1.4
—
—
—
0
0
59
308
2.08
5.75
5.1
3.8
—
—
—
0
0
44
205
2.30
5.67
15.4
7.0
26.1
24.2
mmol/l
2.63
44
192
150
1056
1.69
5.65
3.8
3.5
2.3
2.4
mmol/l
0.29
133
929
74
424
1.92
5.56
3.0
2.4
19.2
23.0
%
1.95
67
366
155
1117
1.65
5.25
4.0
3.6
133.4
89.2
e6/l
0.23
111
805
268
2219
1.70
5.23
5.0
3.9
—
—
—
0
0
15
40
3.86
5.14
2.7
2.7
—
—
—
0
0
183
1384
1.62
5.06
12.6
9.4
0.0
0.0
e9/l
0.04
143
1134
259
2139
1.66
4.96
4.6
4.3
—
—
—
0
0
126
889
1.62
4.51
3.6
3.0
0.4
0.5
e6/l
0.22
94
667
40
201
2.11
4.31
2.1
1.6
0.9
1.3
g/l
1.26
32
184
101
682
1.65
4.28
2.5
1.7
1.2
1.2
mg/l
0.05
86
539
47
252
1.99
4.26
3.4
2.8
10.5
10.3
g/l
0.06
42
233
19
68
2.89
4.18
2.9
5.5
—
—
—
0
0
133
968
1.57
4.12
3.7
3.1
22.0
125.3
e6/l
0.90
100
749
120
854
1.59
4.09
3.7
2.9
—
—
—
0
0
129
938
1.57
3.99
3.7
3.1
—
—
—
0
0
7
8
8.89
3.78
1.9
1.8
—
—
—
0
0
6
5
12.16
3.77
11.7
8.6
—
—
—
0
0
161
1245
1.51
3.70
5.2
3.8
47.5
37.6
ng/l
0.45
114
891
339
3092
1.87
3.68
22.9
14.3
23.4
23.1
mg/l
0.07
310
2445
70
447
1.69
3.63
1.6
1.7
—
—
—
0
0
39
210
1.95
3.51
2.4
2.9
—
—
—
0
0
38
205
1.95
3.40
4.1
3.9
5.5
5.1
kpa
1.42
32
189
50
297
1.79
3.33
1.5
1.4
—
—
—
0
0
91
636
1.57
3.27
2.9
2.8
543.3
553.5
mosm/kgh2o
0.18
77
539
315
2843
1.62
3.20
4.8
4.6
1.9
1.9
mu/l
0.01
294
2568
47
279
1.78
3.14
2.9
2.7
80.3
69.1
e9/l
1.01
27
220
17
68
2.57
3.08
2.2
2.3
128.6
128.0
g/l
—
8
47
23
107
2.22
3.03
10.8
3.9
3.9
4.0
mmol/l
0.43
23
96
11
35
3.21
2.95
1.8
1.6
23.5
18.2
ug/l
0.19
11
35
26
129
2.09
2.94
9.9
3.5
1.3
1.4
mmol/l
0.40
26
121
159
1270
1.43
2.92
2.0
1.9
92.6
96.7
pmol/l
0.53
92
647
93
669
1.52
2.92
3.1
2.5
4.0
4.9
e6/l
0.75
83
590
21
97
2.23
2.82
3.2
4.6
20.9
35.3
mg/l
1.61
16
80
21
97
2.23
2.82
3.2
4.5
179.2
118.7
mg/l
0.24
15
79
14
53
2.70
2.82
3.7
3.6
—
—
—
0
0
16
66
2.49
2.74
3.1
2.5
—
—
—
0
0
14
54
2.65
2.73
4.4
3.3
59.0
57.3
%
0.17
14
54
11
37
3.03
2.71
5.5
2.9
3.0
8.0
nmol/l
0.61
11
37
8
19
4.28
2.69
4.5
3.5
91.4
94.6
nmol/l
—
8
19
25
129
2.00
2.57
2.0
1.9
1.8
1.4
g/l
0.79
19
112
82
591
1.49
2.53
3.0
3.0
2.5
2.5
mmol/l
0.51
71
520
49
314
1.64
2.51
1.5
1.5
—
—
—
0
0
15
63
2.44
2.49
4.5
3.1
—
—
—
0
0
13
51
2.60
2.47
1.2
1.4
—
—
—
0
0
13
51
2.60
2.47
4.6
2.9
4.2
4.7
e9/l
0.39
13
51
16
70
2.34
2.44
8.9
6.6
10.2
11.0
mmol/l
0.53
16
64
16
70
2.34
2.44
8.9
6.6
106.2
104.9
mmol/l
0.59
16
64
107
821
1.42
2.38
3.3
2.8
339.0
6867.4
umol/l
3.31
99
714
55
368
1.58
2.38
3.1
4.2
4.2
45.3
ug/l
1.17
42
311
27
148
1.89
2.35
4.1
3.8
—
—
—
0
0
60
414
1.53
2.27
35.3
20.7
1.4
1.3
inr
—
7
55
60
415
1.53
2.25
1.5
1.3
368.4
508.8
titre
0.57
19
93
10
36
2.83
2.22
3.1
3.2
—
—
—
0
0
84
625
1.44
2.20
1.7
1.5
2.5
2.5
g/l
0.01
51
376
20
101
2.03
2.20
2.7
3.3
0.3
0.2
g/l
—
10
41
349
3297
1.70
2.19
25.8
17.0
78.7
77.2
umol/l
0.32
349
3297
19
95
2.05
2.14
1.5
1.4
252.2
306.0
ug/g
0.45
13
57
14
62
2.31
2.10
1.6
1.7
—
—
—
0
0
103
804
1.39
2.05
1.4
1.4
—
—
—
0
0
73
536
1.45
2.05
1.2
1.3
114.8
40.1
iu/ml
0.77
20
171
350
3318
1.67
2.04
13.7
10.6
24.9
26.1
u/l
0.97
344
3195
31
187
1.72
2.01
1.4
1.2
109.7
198.7
u/ml
0.72
25
167
92
708
1.39
1.99
3.7
3.6
—
—
—
0
0
52
359
1.52
1.97
3.1
2.9
7.9
9.5
umol/l
0.21
44
318
14
64
2.23
1.97
1.4
2.0
—
—
—
0
0
61
436
1.48
1.96
1.3
1.2
—
—
—
0
0
50
343
1.53
1.95
1.9
1.6
—
—
—
0
0
23
128
1.85
1.94
15.3
4.4
—
—
—
0
0
9
33
2.77
1.94
1.1
1.0
—
—
—
0
0
63
457
1.45
1.88
2.2
1.9
—
—
—
0
0
22
122
1.85
1.88
1.3
1.2
—
—
—
0
0
56
397
1.48
1.88
1.5
1.4
—
—
—
0
0
52
363
1.50
1.88
1.4
1.5
—
—
—
0
0
9
34
2.69
1.87
2.0
1.3
—
—
—
0
0
9
34
2.69
1.87
1.7
1.7
—
—
—
0
0
10
41
2.48
1.77
1.1
1.2
—
—
—
0
0
94
740
1.36
1.76
1.7
1.5
19.4
21.1
nmol/l
0.68
87
623
9
36
2.54
1.75
2.1
1.2
—
—
—
0
0
257
2336
1.31
1.67
3.8
3.9
14.9
14.9
pmol/l
0.08
236
2090
15
77
1.99
1.61
1.7
1.5
28248.1
20140.7
e6/l
—
9
55
8
32
2.53
1.60
1.1
1.1
—
—
—
0
0
7
26
2.72
1.58
2.4
2.0
595.3
507.8
e6/l
—
7
20
12
57
2.14
1.56
1.8
1.8
73.5
63.4
%
0.82
12
57
66
504
1.37
1.50
1.2
1.3
14.7
11.8
u/ml
0.12
20
200
30
196
1.58
1.48
1.1
1.4
—
—
—
0
0
9
38
2.40
1.46
2.1
1.2
0.7
0.5
nmol/l
—
9
33
22
133
1.69
1.46
7.7
4.6
1.9
1.5
%
0.81
22
126
22
133
1.69
1.46
7.7
4.6
0.9
0.9
%
0.06
22
127
320
3022
1.37
1.44
4.8
4.7
5.9
6.0
mmol/l
0.26
294
2754
5
16
3.15
1.44
1.2
1.1
—
—
—
0
0
9
40
2.28
1.41
2.1
1.4
36.5
31.4
g/l
—
9
35
174
1532
1.25
1.36
5.0
5.2
0.0
0.0
estimate
0.50
39
291
31
211
1.51
1.30
3.4
2.3
4.4
3.8
e9/l
0.65
31
162
8
34
2.38
1.30
2.1
1.2
—
—
—
0
0
5
18
2.80
1.29
15.0
18.3
1518.0
1448.8
nmol/l
—
5
18
5
18
2.80
1.29
1.2
1.8
—
—
—
0
0
5
18
2.80
1.29
12.4
13.6
1065.6
863.4
nmol/l
—
5
18
11
55
2.03
1.28
1.2
1.1
—
—
—
0
0
5
19
2.65
1.22
3.4
1.4
0.8
1.0
g/l
—
5
19
119
1015
1.25
1.21
2.6
2.4
55.6
56.9
u/l
0.19
105
939
6
26
2.33
1.19
1.8
2.1
—
—
—
0
0
8
38
2.13
1.19
1.3
1.2
—
—
—
0
0
174
1549
1.23
1.18
3.9
3.8
0.0
0.0
estimate
0.00
36
282
7
30
2.36
1.13
2.6
2.0
—
—
—
0
0
307
2911
1.28
1.12
5.6
5.9
39.1
40.1
mmol/mol
1.36
286
2699
73
595
1.28
1.08
2.0
1.7
1161.0
1207.1
nmol/l
0.18
57
447
7
34
2.08
1.03
3.6
1.4
—
—
—
0
0
9
47
1.94
1.03
1.3
1.0
—
—
—
0
0
10
53
1.91
1.02
3.8
2.4
—
—
—
0
0
9
48
1.90
1.01
1.2
1.4
—
—
—
0
0
169
1520
1.20
0.99
3.9
3.7
0.0
0.0
estimate
0.00
38
291
335
3226
1.32
0.98
20.3
13.5
—
—
—
0
0
14
85
1.67
0.95
1.1
1.2
—
—
—
0
0
6
27
2.24
0.94
1.2
1.2
—
—
—
0
0
10
55
1.84
0.93
1.0
1.8
—
—
—
0
0
93
1076
0.82
0.90
3.0
3.0
—
—
—
0
0
13
79
1.67
0.89
2.0
1.3
—
2.9
—
0
15
294
2799
1.22
0.88
24.4
15.5
39.3
40.1
%
1.17
213
1978
109
952
1.20
0.86
5.1
3.9
—
—
—
0
0
27
197
1.40
0.85
1.0
1.3
—
—
—
0
0
8
45
1.79
0.84
1.1
1.2
—
—
—
0
0
6
34
1.78
0.76
2.3
1.2
—
—
nmol/l
—
0
0
13
83
1.59
0.76
1.5
1.1
—
51.4
—
0
7
5
24
2.10
0.75
1.0
1.0
—
—
—
0
0
5
24
2.10
0.75
1.8
1.3
—
—
—
0
0
40
319
1.28
0.73
1.6
1.6
—
—
—
0
0
35
274
1.31
0.73
4.4
4.3
1.5
0.9
%
—
9
90
20
274
0.71
0.72
1.3
1.4
—
—
—
0
0
25
186
1.37
0.72
1.1
1.3
—
—
—
0
0
18
126
1.45
0.71
1.8
2.8
—
—
—
0
0
9
57
1.59
0.71
1.3
1.5
—
—
—
0
0
5
26
1.94
0.71
1.4
1.2
0.1
0.1
u/ml
—
5
11
12
77
1.58
0.69
1.2
1.4
—
—
—
0
0
9
59
1.54
0.69
1.4
1.2
—
—
—
0
0
29
224
1.32
0.67
2.2
2.0
15.4
13.5
nmol/l
0.49
20
206
5
28
1.80
0.66
1.0
1.2
—
—
—
0
0
7
44
1.60
0.65
1.0
1.1
—
—
—
0
0
7
44
1.60
0.65
1.0
1.1
—
—
—
0
0
94
834
1.17
0.63
1.5
1.7
1.3
1.4
mmol/l
0.45
83
701
32
254
1.28
0.62
4.3
4.4
0.4
0.2
%
—
8
81
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
6
35
1.73
0.58
1.2
1.1
—
—
—
0
0
30
239
1.28
0.57
4.7
4.4
0.1
0.2
%
—
7
66
6
37
1.63
0.56
1.0
1.2
—
—
—
0
0
14
99
1.43
0.55
1.0
1.3
—
—
—
0
0
17
125
1.38
0.54
1.6
1.9
—
—
—
0
0
6
38
1.59
0.54
3.7
1.8
89.9
89.2
%
—
6
38
110
1000
1.14
0.53
3.3
3.1
8.1
7.5
mmol/l
0.57
102
829
6
39
1.55
0.53
1.2
1.9
22.3
32.3
pg
—
6
39
6
39
1.55
0.53
1.2
1.3
—
—
—
0
0
351
3442
1.25
0.53
33.3
21.2
4.4
4.5
e12/l
2.26
345
3335
351
3442
1.25
0.53
33.4
21.2
6.8
6.7
e9/l
0.35
346
3336
105
953
1.14
0.52
3.3
3.3
1189.2
188.8
mg/l
0.64
74
615
9
64
1.42
0.52
1.3
1.1
—
—
—
0
0
71
629
1.16
0.49
1.8
1.8
406.9
446.9
pmol/l
0.85
60
515
7
109
0.64
0.49
17.9
11.0
—
—
—
0
0
19
244
0.77
0.48
1.3
1.5
—
—
—
0
0
32
264
1.23
0.47
5.5
3.7
—
—
—
0
0
5
32
1.57
0.42
2.6
2.6
—
—
—
0
0
14
105
1.35
0.41
1.5
1.6
—
—
—
0
0
5
33
1.52
0.41
1.2
3.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
76
688
1.13
0.40
1.3
1.3
0.9
1.4
u/ml
0.61
21
194
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
54
606
0.87
0.38
3.0
3.0
1.4
0.8
ug/l
0.94
39
395
9
70
1.29
0.37
2.1
2.2
—
—
—
0
0
6
42
1.44
0.35
1.2
1.2
—
—
—
0
0
6
42
1.44
0.35
1.2
1.2
—
—
—
0
0
6
43
1.40
0.35
23.7
7.5
8.0
6.7
mmol/l
—
6
35
43
380
1.15
0.33
2.4
2.2
124.8
125.4
ug/g
0.01
38
315
107
1000
1.10
0.32
4.0
4.0
9.3
8.9
mg/mmol
0.02
73
630
34
296
1.16
0.31
4.2
4.3
—
—
—
0
0
14
175
0.79
0.31
2.9
2.6
—
—
—
0
0
27
231
1.18
0.30
1.1
1.2
—
—
—
0
0
80
862
0.91
0.29
3.9
3.5
—
—
—
0
0
30
264
1.15
0.25
4.6
3.5
—
—
—
0
0
73
679
1.09
0.25
6.0
5.0
—
—
—
0
0
25
218
1.16
0.24
2.8
2.5
—
12.1
—
0
8
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
110
1049
1.07
0.21
4.6
4.8
2.4
2.7
ug/l
0.23
100
937
0
13
0.00
0.21
0.0
1.1
—
133.1
—
0
13
10
80
1.26
0.20
1.1
1.1
—
—
—
0
0
5
66
0.75
0.17
1.6
1.3
3.9
3.9
mmol/l
—
5
60
87
831
1.06
0.16
5.0
3.9
0.0
0.0
estimate
0.80
36
283
63
664
0.94
0.15
4.4
4.1
1.0
1.0
kg/l
—
10
99
27
246
1.11
0.15
4.2
4.2
1.1
0.4
%
—
7
60
7
86
0.81
0.14
1.6
1.4
—
—
—
0
0
16
181
0.88
0.14
1.8
1.7
—
—
—
0
0
15
170
0.88
0.14
3.1
2.8
0.2
0.1
e6/l
0.13
15
164
15
170
0.88
0.14
1.1
1.5
—
—
—
0
0
6
55
1.09
0.09
1.0
1.4
—
—
—
0
0
11
123
0.89
0.08
1.1
1.1
—
—
—
0
0
15
137
1.10
0.07
1.0
1.1
—
—
—
0
0
7
84
0.83
0.07
1.1
1.3
—
—
—
0
0
12
132
0.91
0.06
1.5
1.6
—
—
—
0
0
9
100
0.90
0.06
3.0
3.0
—
—
—
0
0
38
367
1.04
0.05
1.5
1.3
—
—
—
0
0
308
3067
1.02
0.03
4.5
4.5
1.4
1.5
mmol/l
1.74
287
2805
316
3148
1.02
0.03
5.3
5.1
2.6
2.7
mmol/l
1.99
292
2873
297
2962
1.01
0.01
4.1
4.1
1.3
1.3
mmol/l
0.32
278
2695
21
204
1.03
0.00
2.9
3.0
—
—
—
0
0
10
98
1.02
0.00
2.3
5.3
—
—
—
0
0
17
168
1.01
0.00
2.8
4.2
—
—
—
0
0
11
111
0.99
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
6.4
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
0.00
1.1
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
3.8
—
0
5
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
7
77
0.91
0.00
1.1
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.2
1.2
—
—
—
0
0
5
52
0.96
0.00
1.4
1.4
—
—
—
0
0
308
3080
1.00
0.00
4.7
4.6
4.5
4.6
mmol/l
1.83
286
2834
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
0.00
1.1
1.3
—
—
—
0
0
8
85
0.94
0.00
1.1
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
38.2
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_INTRATHORACIC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_INTRATHORACIC 1.723 [1.35, 2.2] < 0.001
Birth year 0.99 [0.98, 1.0] 0.024

During the follow-up period (1.1.1998 — 31.12.2019), 170 out of 792 females with CD2_BENIGN_INTRATHORACIC died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_INTRATHORACIC 1.914 [1.5, 2.44] < 0.001
Birth year 0.988 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 144 out of 631 males with CD2_BENIGN_INTRATHORACIC died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_INTRATHORACIC.

N-year risk Females Males
1 0.14% 0.406%
5 0.988% 2.501%
10 2.339% 6.167%
15 4.24% 11.267%
20 7.286% 18.197%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_INTRATHORACIC – Benign neoplasm of other and unspecified intrathoracic organs

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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