thymus neoplasm: A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
76 |
4. Check minimum number of eventsNone |
76 |
5. Include endpointsNone |
76 |
6. Filter based on genotype QC (FinnGen only) |
76 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D15
- Name in latin
- Neoplasma benignum thymi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Thymus
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Thymus
- Benign neoplasm of other and unspecified intrathoracic organs
- Benign neoplasm of other and unspecified intrathoracic organs
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 372 | 193 | 175 |
| Only index persons | 325 | 170 | 155 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.88 | 60.91 | 56.30 |
| Only index persons | 57.65 | 59.27 | 55.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 76 | 39 | 37 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | 61.70 | 58.78 | 64.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 62
- Matched controls
- 620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
83.7
60
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
+∞
25.8
23
*
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
381.6
25.7
24
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
17.2
16.8
28
28
GEC23
NOMESCO Finland
Transsternal thymectomy
+∞
15.2
14
*
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
+∞
14.1
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
10.6
47
196
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
8.2
10.3
25
47
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
9.6
9
*
8582/3-C37.9
ICD-O-3
Thymoma, type AB of thymus
+∞
9.6
9
*
G70.0
ICD-10 Finland
Myasthenia gravis
103.6
8.6
9
*
N07AA02
ATC
pyridostigmine; systemic
103.6
8.6
9
*
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
8.5
8
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
10.9
8.5
16
19
108
Kela drug reimbursment
Myasthenia gravis
90.5
7.6
8
*
R4110
NOMESCO Finland
Physiotherapy
4.8
7.1
28
91
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
77.5
6.6
7
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
147
5.15
11.57
2.4
2.6
—
—
—
0
0
62
302
6.72
11.26
9.5
7.0
1.2
1.2
mmol/l
0.14
57
258
20
38
6.79
10.79
15.3
9.5
0.6
0.7
%
0.41
20
38
19
39
6.16
9.42
15.9
9.3
1.2
1.6
%
0.65
19
39
57
285
5.00
9.30
3.7
4.2
—
—
—
0
0
45
227
3.41
6.42
4.1
3.4
—
—
—
0
0
61
373
4.22
6.39
14.1
8.2
4.1
4.2
e9/l
0.19
52
325
24
90
3.44
5.39
3.4
3.1
5.9
2.8
e6/l
0.35
13
49
39
201
2.93
5.04
2.5
3.1
24.1
29.1
u/l
1.68
39
191
35
174
2.87
4.78
3.7
3.2
0.2
0.6
e6/l
1.55
27
126
25
103
3.13
4.76
3.4
2.9
0.6
0.9
e6/l
0.39
14
62
13
37
4.03
4.26
7.8
7.5
26.0
25.0
mmol/l
0.74
13
37
7
8
9.48
3.86
1.3
1.3
—
—
—
0
0
24
109
2.76
3.76
2.1
3.2
0.8
0.8
mmol/l
0.47
24
104
35
192
2.53
3.75
2.5
2.1
161.5
193.3
u/l
0.26
35
181
7
9
8.42
3.64
1.3
1.2
—
—
—
0
0
10
27
4.11
3.48
3.3
2.5
—
—
—
0
0
38
239
2.18
2.78
1.7
1.8
91.1
96.3
pmol/l
0.41
29
111
12
44
3.05
2.69
1.6
1.7
—
—
—
0
0
5
7
7.54
2.59
1.8
1.6
37.3
25.6
ug/l
—
5
7
24
129
2.26
2.55
3.0
3.1
25.3
160.3
ng/l
1.55
19
105
19
93
2.39
2.48
2.3
2.3
2.3
2.3
g/l
0.06
19
86
16
73
2.51
2.41
1.6
1.6
—
—
—
0
0
5
8
6.59
2.41
1.0
1.5
4.7
2.9
u/ml
—
5
8
10
36
3.05
2.30
5.0
4.2
2.0
0.7
mmol/l
—
10
31
16
77
2.37
2.15
3.6
4.0
294.8
261.0
u/l
0.38
16
72
7
20
3.74
2.11
2.4
1.5
—
—
—
0
0
10
38
2.88
2.10
1.5
1.2
—
—
—
0
0
19
100
2.20
2.09
2.3
2.4
12.3
13.3
umol/l
0.23
19
92
6
15
4.24
2.08
1.0
1.2
—
—
—
0
0
19
101
2.17
2.04
1.9
1.7
—
—
—
0
0
43
313
1.86
1.86
4.8
4.6
0.0
0.0
estimate
—
8
58
8
29
2.96
1.85
3.3
1.0
—
—
—
0
0
15
75
2.25
1.85
1.9
1.7
—
—
—
0
0
53
416
1.91
1.77
3.6
3.2
76.4
53.9
u/l
0.33
53
388
43
317
1.82
1.76
3.5
3.5
0.0
0.0
estimate
—
7
55
41
312
1.68
1.39
3.5
3.5
0.0
0.0
estimate
—
7
61
5
17
3.07
1.38
2.0
1.6
—
—
—
0
0
22
144
1.74
1.27
1.6
1.4
18.1
22.1
nmol/l
0.88
22
117
5
19
2.74
1.23
1.6
1.5
—
—
—
0
0
20
130
1.73
1.18
3.5
2.8
2.5
2.5
mmol/l
0.03
15
114
7
31
2.38
1.14
7.6
2.6
1.2
1.5
%
—
7
31
7
32
2.30
1.11
1.6
1.4
—
—
—
0
0
5
22
2.36
1.05
2.6
1.8
—
—
—
0
0
32
243
1.55
1.02
5.2
3.8
40.3
47.2
ng/l
0.14
26
174
6
27
2.32
0.96
6.2
4.5
24.2
24.6
mmol/l
—
6
27
6
30
2.08
0.89
9.5
3.0
51.1
45.5
%
—
6
30
29
221
1.50
0.89
2.5
2.6
61.5
57.2
u/l
0.34
29
206
66
602
1.73
0.82
21.8
12.9
81.1
80.0
ml/min/173m2
0.16
60
496
0
26
0.00
0.80
0.0
1.7
—
—
—
0
0
9
55
1.72
0.77
8.9
3.5
64.0
88.7
ng/l
—
9
45
13
86
1.62
0.72
1.2
1.3
—
—
—
0
0
8
52
1.60
0.62
2.9
1.8
—
—
—
0
0
15
107
1.50
0.61
1.1
1.3
1.2
10.0
u/ml
—
5
52
7
50
1.44
0.46
2.6
1.5
—
—
—
0
0
6
90
0.64
0.45
10.7
8.5
—
—
—
0
0
5
32
1.60
0.43
1.0
1.3
—
148.0
—
0
14
15
186
0.76
0.36
3.4
4.3
16.7
22.2
%
—
9
101
15
119
1.32
0.35
1.9
1.9
460.3
505.2
pmol/l
0.33
15
106
8
64
1.28
0.28
1.3
2.8
31.8
7.5
ug/l
—
8
55
50
468
1.20
0.26
3.9
3.9
15.0
15.0
pmol/l
0.00
43
413
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
6
50
1.22
0.20
1.5
4.1
1.2
1.2
mmol/l
—
6
44
5
67
0.73
0.17
2.6
3.7
—
—
—
0
0
40
375
1.14
0.17
3.1
2.8
—
—
—
0
0
8
95
0.82
0.14
1.6
1.5
—
—
—
0
0
15
134
1.15
0.12
1.1
1.2
0.8
1.0
u/ml
—
5
39
13
115
1.16
0.11
2.1
1.7
978.3
1382.5
nmol/l
1.03
13
91
18
191
0.92
0.05
1.3
1.7
1.4
1.4
mmol/l
0.03
18
161
24
246
0.96
0.00
4.7
3.7
—
—
—
0
0
23
228
1.01
0.00
5.7
4.4
3.9
2.0
ug/l
0.80
23
201
18
181
0.99
0.00
4.9
3.7
0.0
0.0
estimate
—
7
56
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
95.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_THYMUS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_THYMUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_THYMUS – Benign neoplasm: Thymus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data