Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9)

CD2_BENIGN_INTRATHORACIC_NOS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D15.7&, D15.9& Hospital discharge: ICD-9 — 212[8-9]\|2124 Hospital discharge: ICD-8 — 2124 Cause of death: ICD-10 — D15.7&, D15.9& Cause of death: ICD-9 — 212[8-9]\|2124 Cause of death: ICD-8 — 2124 2 out of 7 registries used, show all original rules.	93
4. Check minimum number of events None	93
5. Include endpoints None	93
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	CD2_BENIGN_INTRATHORACIC_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D15[7\|9]
HD_ICD_9	212[8-9]\|2124
HD_ICD_8	2124
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D15[7\|9]
COD_ICD_9	212[8-9]\|2124
COD_ICD_8	2124
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	643	324	311
Only index persons	503	282	221
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	53.15	54.00	51.91
Only index persons	50.65	52.73	48.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	45	47
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	53.54	53.98	53.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
93: Matched controls
930

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D15.9

ICD-10 Finland

Benign neoplasm: Intrathoracic organ, unspecified

+∞

44.4

D15.7

ICD-10 Finland

Benign neoplasm: Other specified intrathoracic organs

+∞

41.9

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

6.8

15.3

GAE06

NOMESCO Finland

Excision of lesion of chest wall

+∞

9.5

UGC12

NOMESCO Finland

Flexible bronchoscopy

5.3

8.0

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

4.0

7.4

D15.1

ICD-10 Finland

Benign neoplasm: Heart

+∞

7.4

2129X

ICD-9 Finland

Benign neoplasm of respiratory and intrathoracic organs, Site unspecified

+∞

6.3

D15.2

ICD-10 Finland

Benign neoplasm: Mediastinum

+∞

6.3

21240

ICD-8 Finland

Benign neoplasm of respiratory system, Pleura

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3003434) Protein [Mass/volume] in Pleural fluid

12.69

3.81

2.5

1.6

37.83

25.20

g/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

332

2.19

3.37

7.2

6.7

1.21

1.22

mmol/l

0.08

277

(3044640) Blood type and Crossmatch panel - Blood

233

2.16

3.16

2.3

—

(3012441) Differential panel - Pleural fluid

10.46

3.01

2.8

1.6

—

(40768806) Pleura Pathology biopsy report

8.71

2.78

2.2

2.3

—

(3017732) Neutrophils [#/volume] in Blood

3.06

2.76

2.3

2.6

4.14

9.95

e9/l

0.45

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.61

2.69

1.1

1.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

3.58

2.46

1.9

1.6

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

3.88

2.42

1.6

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

4.85

2.31

1.2

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

323

1.84

2.17

2.7

2.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

167

1.97

2.17

2.2

2.3

—

(3022313) Gas panel - Capillary blood

3.10

2.14

2.2

5.3

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.22

2.06

5.8

7.1

1.13

1.03

mmol/l

1.06

(3021589) Normoblasts [#/volume] in Blood

311

1.79

1.99

13.8

9.0

0.00

e9/l

0.66

257

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

287

1.77

1.89

2.2

2.3

76.86

75.59

nmol/l

0.13

248

(3020630) Protein [Mass/volume] in Serum or Plasma

2.40

1.83

1.8

3.2

66.00

66.87

g/l

0.15

(3022217) INR in Platelet poor plasma by Coagulation assay

348

1.71

1.74

19.4

13.6

1.23

1.27

inr

0.18

(40768804) Tissue Pathology biopsy report

302

1.71

1.73

2.2

1.9

—

(40758558) Short blood count panel - Blood

174

1.78

1.61

7.3

7.7

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

424

1.65

1.54

4.6

4.3

6.40

6.65

mmol/l

0.37

396

(4035726) Immunohistochemistry procedure

2.02

1.50

1.1

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.51

1.50

6.0

3.8

25.60

24.67

mmol/l

—

(3019198) Lymphocytes [#/volume] in Blood

361

1.61

1.44

5.7

5.6

1.72

1.83

e9/l

0.32

325

(3042936) Bacteria identified in Isolate by Culture

1.90

1.43

2.1

1.7

—

(3013115) Eosinophils [#/volume] in Blood

371

1.61

1.43

5.5

6.1

0.17

0.19

e9/l

0.27

330

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.72

1.39

4.5

2.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

335

1.59

1.38

6.1

6.2

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.96

1.34

4.6

4.1

2.37

95.26

ug/l

0.53

(3006315) Basophils [#/volume] in Blood

357

1.57

1.31

5.5

0.03

0.04

e9/l

0.17

314

(3001604) Monocytes [#/volume] in Blood

357

1.57

1.31

5.5

0.60

0.59

e9/l

0.07

315

(3025941) Bacteria identified in Stool by Culture

2.16

1.31

1.2

1.4

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.49

1.26

1.2

1.8

—

(40768443) Skin Pathology biopsy report

2.40

1.20

1.2

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.58

1.16

3.2

1.2

—

(3002256) Pathology report gross observation

1.82

1.16

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

437

1.49

1.08

2.8

2.7

—

(3000492) Spirometry study

1.88

1.06

1.4

1.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

108

1.70

1.06

1.9

1.6

—

(3044889) 12 lead EKG panel

499

1.50

1.05

4.9

4.0

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.08

1.02

1.1

1.8

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.85

1.02

3.5

3.8

—

(4200892) Spirometry reversibility

1.88

0.99

1.5

1.3

—

(3019225) pH of Specimen

1.85

0.95

3.6

5.1

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.22

0.93

1.2

2.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

105

1.63

0.89

1.4

1.9

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

284

1.44

0.88

4.0

2.7

125.29

114.09

ug/l

0.11

261

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

294

1.43

0.87

4.7

4.1

16.92

56.16

ng/l

1.65

207

(3023368) Bacteria identified in Blood by Culture

204

1.46

0.82

3.8

4.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

134

1.53

0.79

2.1

1.6

1282.15

1257.60

nmol/l

0.04

101

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

208

1.42

0.73

1.9

2.1

161.22

205.88

u/l

0.38

197

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.61

0.72

1.7

1.6

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.68

0.68

1.9

1.2

282.00

152.97

u/ml

—

(3000330) Specific gravity of Urine by Test strip

1.70

0.62

1.6

5.0

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.59

0.61

9.4

4.1

1.21

1.22

mmol/l

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.59

0.61

4.3

2.6

132.63

142.93

ng/l

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.61

0.0

6.3

—

32.73

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.56

0.60

1.4

1.6

—

(3002032) Base excess in Venous blood by calculation

1.58

0.57

4.8

4.2

3.42

2.00

mmol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.50

0.55

1.4

1.7

—

(3018418) pH of Serum or Plasma

210

1.33

0.53

6.2

3.7

7.41

7.40

—

(40761511) CBC panel - Blood by Automated count

766

0.73

0.53

21.0

13.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

119

0.64

0.49

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

279

1.28

0.48

5.1

4.1

—

(3010813) Leukocytes [#/volume] in Blood

817

0.72

0.46

29.3

20.6

6.77

6.70

e9/l

0.12

792

(3009542) Hematocrit [Volume Fraction] of Blood

817

0.72

0.46

28.6

20.6

39.79

40.43

0.64

769

(3026361) Erythrocytes [#/volume] in Blood

817

0.72

0.46

29.2

20.6

4.43

4.52

e12/l

0.87

790

(3013512) EKG study

215

1.29

0.45

5.2

4.0

—

(3035941) MCH [Entitic mass]

816

0.73

0.44

29.0

20.5

29.80

30.30

1.64

804

(3024731) MCV [Entitic volume]

816

0.73

0.44

29.1

20.6

90.22

90.92

0.76

804

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.65

0.44

9.2

3.4

25.38

24.25

mmol/l

—

(3048689) Calprotectin [Mass/mass] in Stool

1.42

0.42

1.5

2.0

126.57

135.67

ug/g

—

(3007461) Platelets [#/volume] in Blood

815

0.73

0.42

29.3

20.7

249.00

248.47

e9/l

0.02

791

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.3

—

3.71

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.41

0.0

1.2

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.41

0.0

1.8

—

3.42

—

(40761536) Microorganisms panel - Urine sediment

1.36

0.41

7.1

3.4

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

0.24

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

712

0.79

0.40

4.6

4.5

1.43

1.45

mmol/l

0.18

644

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.40

0.0

2.8

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

488

0.81

0.40

4.0

3.0

32.77

52.67

u/l

3.35

463

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.41

0.39

9.6

7.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

218

0.78

0.35

2.7

4.9

21.98

21.06

—

110

(3003694) ABO and Rh group [Type] in Blood

175

1.26

0.34

1.5

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.39

0.34

1.9

1.6

—

(3026008) Bacteria identified in Urine by Culture

223

1.23

0.33

3.6

3.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

707

0.81

0.33

4.9

4.7

5.83

5.99

mmol/l

0.53

644

(3021601) Nitrite [Presence] in Urine by Test strip

349

1.20

0.33

6.1

5.4

0.00

estimate

-0.00

(3041096) Erythrocytes [Presence] in Urine by Automated

205

1.23

0.32

4.0

3.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.35

0.31

1.3

1.8

—

(3029937) Albumin [Presence] in Urine by Test strip

206

1.22

0.30

5.4

3.9

0.00

estimate

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

422

1.18

0.28

8.8

9.9

4.05

4.06

e9/l

0.01

365

(3009261) Glucose [Presence] in Urine by Test strip

353

1.18

0.28

4.7

3.9

0.00

estimate

-0.00

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

246

1.20

0.28

2.6

2.2

55.48

56.91

u/l

0.09

228

(3002385) Erythrocyte distribution width [Ratio]

625

1.19

0.27

21.7

16.8

15.37

15.02

0.18

618

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

692

0.84

0.26

4.1

4.0

1.25

1.27

mmol/l

0.16

626

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

152

1.23

0.26

1.1

1.3

0.83

1.06

u/ml

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.30

0.25

1.7

1.5

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.30

0.25

4.5

4.0

106.73

103.99

mmol/l

1.83

(1761868) Lipid panel - Serum or Plasma

250

1.17

0.23

2.9

3.0

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.23

0.22

4.6

5.3

0.68

0.72

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.23

0.22

4.6

1.04

1.50

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.20

0.22

1.4

1.6

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.1

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.21

0.0

2.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

4.3

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.21

0.0

1.3

—

89.45

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(4146454) Self-monitoring of blood glucose

0.00

0.21

0.0

1.6

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.6

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

4.3

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.21

0.0

2.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.7

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.7

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.9

—

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

2.4

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.20

0.0

1.1

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.20

0.0

1.4

—

111.21

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

109

1.22

0.20

1.2

1.4

34.16

20.73

u/ml

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.19

0.20

1.3

2.9

—

(3012516) Albumin [Mass/volume] in Urine

195

1.17

0.20

3.8

3.2

21.79

45.63

mg/l

0.84

122

(3012544) pH of Venous blood

1.22

0.18

1.6

4.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

284

1.14

0.18

1.8

1.9

88.62

92.06

pmol/l

0.16

132

(3035350) Ketones [Presence] in Urine by Test strip

353

1.13

0.18

4.9

3.9

0.00

estimate

-0.00

(3019550) Sodium [Moles/volume] in Serum or Plasma

747

1.18

0.18

21.5

16.1

139.77

139.72

mmol/l

0.05

728

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

714

0.87

0.18

4.8

4.5

4.53

4.62

mmol/l

0.26

653

(3020682) Albumin/Creatinine [Ratio] in Urine

207

1.15

0.17

5.2

3.8

1.81

5.70

mg/mmol

1.54

130

(3023103) Potassium [Moles/volume] in Serum or Plasma

749

1.16

0.16

21.6

16.3

3.96

3.99

mmol/l

0.39

730

(40768797) Stomach Pathology biopsy report

103

1.19

0.14

1.2

—

(3000494) Fungus identified in Specimen by Culture

1.19

0.14

1.3

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

502

0.91

0.13

4.9

4.0

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

144

1.13

0.11

2.8

2.9

2.48

2.45

mmol/l

0.57

124

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

692

1.11

0.11

16.7

13.4

80.37

80.54

ml/min/173m2

0.02

552

(3022621) pH of Urine by Test strip

1.17

0.10

2.4

2.3

—

(3000991) Gas panel - Venous blood

1.06

0.09

4.3

5.3

—

(3022145) Colonoscopy Study observation

0.83

0.08

1.5

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.10

0.08

1.5

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.10

0.08

1.5

1.7

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.07

0.07

1.9

1.8

1.38

1.53

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.09

0.07

1.4

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.07

0.07

12.9

7.2

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.14

0.07

3.8

3.3

1.73

1.66

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

733

0.92

0.07

5.1

5.0

2.59

2.74

mmol/l

0.58

666

(3018095) Leukocytes [#/volume] in Urine

278

1.06

0.05

3.2

3.4

537.20

74.97

e6/l

0.64

197

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

120

1.10

0.05

1.2

1.3

115.20

35.62

iu/ml

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

259

0.95

0.03

3.9

2.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

118

0.92

0.03

2.0

2.7

2.83

2.89

e6/l

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

677

0.96

0.01

6.0

5.9

38.65

40.04

mmol/mol

0.71

632

(3007164) IgA [Mass/volume] in Serum or Plasma

144

1.05

0.00

1.5

1.4

2.15

2.39

g/l

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

108

1.02

0.00

4.6

2.6

18.40

21.38

0.62

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

733

0.98

0.00

20.0

14.2

15.20

23.46

mg/l

3.17

578

(3011397) Hemoglobin [Presence] in Urine by Test strip

165

0.96

0.00

5.5

3.7

—

(3037522) Nuclear Ab [Titer] in Serum

1.06

0.00

1.5

1.3

—

467.83

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

104

0.96

0.00

1.6

1.3

—

(36304419) Bacteria [Presence] in Urine

199

1.01

0.00

2.9

2.6

—

(3031040) Bacteria [#/volume] in Urine by Automated count

466

1.02

0.00

4.9

4.2

—

45.70

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

3.42

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3019977) pH of Arterial blood

0.00

0.0

4.6

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

1.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

3.2

—

241.00

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

4.6

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

8.22

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.2

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.4

—

13.40

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

2.4

—

3.72

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

0.0

1.6

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

4.6

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

5.2

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

0.0

1.0

—

134.33

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

0.0

1.8

—

1.20

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.5

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

780

1.00

-0.00

22.0

16.5

83.27

77.65

umol/l

0.37

780

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

2.1

—

69.39

—

(3019060) Gas panel - Arterial blood

0.89

-0.00

6.2

3.7

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

2.0

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

2.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.1

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.1

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.7

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

3.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.98

-0.00

1.9

2.0

299.57

369.62

nmol/l

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

26.28

—

(3010503) CD19 cells [#/volume] in Blood

0.00

-0.00

0.0

1.9

—

0.20

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.3

—

(40761535) Cells panel - Urine sediment

0.90

-0.00

7.2

4.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

2.5

—

36.30

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

227.22

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_INTRATHORACIC_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_INTRATHORACIC_NOS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_INTRATHORACIC_NOS – Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9)

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints