Chronic hepatitis, not elsewhere classified

K11_CHRONHEP

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K73
  • Hospital discharge: ICD-9 5714A|5714X
  • Hospital discharge: ICD-8 57001
  • Cause of death: ICD-10 K73
  • Cause of death: ICD-9 5714A|5714X
  • Cause of death: ICD-8 57001

2 out of 7 registries used, show all original rules.

1326

4. Check minimum number of events

None

1326

5. Include endpoints

None

1326

6. Filter based on genotype QC (FinnGen only)

1279

Control definitions (FinnGen only)

Control exclude
K11_LIVER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K70-K77
Name in latin
Hepatitis chronica non alibi classificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7890 4726 3100
Only index persons 6673 4123 2550
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.09
Only index persons 0.13 0.15 0.10
Median age at first event (years)
Whole population 55.74 57.47 53.03
Only index persons 54.41 56.19 51.54

-FinnGen-

Key figures

All Female Male
Number of individuals 1279 820 459
Unadjusted period prevalence (%) 0.26 0.29 0.21
Median age at first event (years) 54.90 54.64 55.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1326
Matched controls
13260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
9.1
310.5
488
795
A07EA06
ATC
budesonide; oral, local oral
21.0
307.7
316
195
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
63.9
307.7
237
45
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
502.6
307.7
312
8
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
6617.4
307.7
457
*
A05AA02
ATC
ursodeoxycholic acid; oral
83.7
307.7
268
40
L04AX01
ATC
azathioprine; systemic
29.7
307.7
459
232
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
153.8
307.7
512
54
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
307.7
560
*
K76.9
ICD-10 Finland
Liver disease, unspecified
263.6
307.7
220
10
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
12.9
307.7
497
589
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
81.0
282.8
151
21
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
2486.3
235.6
221
*
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
22.6
233.1
176
89
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
229.0
213
*
K83.0
ICD-10 Finland
Cholangitis
28.0
184.7
127
50
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
176.1
165
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.7
165.0
386
892
L04AA06
ATC
mycophenolic acid; systemic
19.6
163.4
130
73
L01BB02
ATC
mercaptopurine; oral
26.2
160.8
113
47
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
157.9
674
2504
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
15.1
154.0
141
104
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
147.7
139
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
23.2
142.7
105
49
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
139.1
131
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
63.9
110.1
61
10
L04AD02
ATC
tacrolimus; systemic
23.6
110.0
80
36
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
16.9
109.6
93
59
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
356.5
100.5
100
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.3
99.3
661
3067
R94.5
ICD-10 Finland
Abnormal results of liver function studies
19.2
98.3
78
43
H02AB06
ATC
prednisolone; systemic
3.3
95.9
843
4576
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.5
93.1
106
109
127
Kela drug reimbursment
Transplant complication
14.4
91.1
84
62
L04AD01
ATC
ciclosporin; systemic
11.6
85.9
91
84
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
20.3
82.9
64
33
R18
ICD-10 Finland
Ascites
12.8
82.0
81
67
C03DA01
ATC
spironolactone; oral
4.1
81.9
261
743
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
12.1
81.7
84
74
Z94.4
ICD-10 Finland
Liver transplant status
221.1
81.3
83
*
UJF30
NOMESCO Finland
Ileoscopy through colon
4.1
80.9
260
744
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
+∞
77.9
74
*
K51.5
ICD-10 Finland
Left sided colitis
8.1
76.0
106
141
D97
ICPC
Liver disease NOS
42.3
74.5
45
11
JJC00
NOMESCO Finland
Allogenic transplantation of liver
360.4
69.3
69
*
A07EC02
ATC
mesalazine; oral, rectal
5.1
67.9
154
333
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
7.2
67.8
104
154
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
5.4
65.2
136
273
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.4
64.4
177
447
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
83.4
63.7
71
9
UJF32
NOMESCO Finland
Coloscopy
2.7
60.4
464
2200
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
560.4
55.0
54
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
10.6
54.9
61
60
ZX120
NOMESCO Finland
Intravenous
3.6
54.5
207
655
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
10.2
51.9
59
60
5714X
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ALIA SEU NUD]
+∞
51.4
49
*
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
50.3
48
*
C10AC01
ATC
colestyramine; oral
6.6
49.6
82
131
N02AX02
ATC
tramadol; systemic, rectal
2.3
49.0
671
4054
K72.9
ICD-10 Finland
Hepatic failure, unspecified
248.8
47.3
48
*
C03CA01
ATC
furosemide; systemic
2.4
45.3
420
2129
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
238.1
45.2
46
*
H02AB07
ATC
prednisone; oral
2.8
45.0
263
1065
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
44.7
681
4250
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
44.0
370
1791
UJK02
NOMESCO Finland
ERCP
6.7
43.8
71
111
A02BC02
ATC
pantoprazole; systemic
2.4
42.2
988
7274
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
81.3
42.1
47
6
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
41.9
40
*
J01MA02
ATC
ciprofloxacin; systemic
2.2
41.5
580
3467
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
41.4
558
3285
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.4
41.0
386
1956
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.4
40.8
362
1787
103
Kela drug reimbursment
Diabetes, insulin-treated
2.3
40.6
403
2089
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
6.3
39.5
68
113
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
38.7
37
*
A06AD11
ATC
lactulose; oral
2.8
38.7
233
953
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.6
38.7
75
140
K92.0
ICD-10 Finland
Haematemesis
7.6
37.5
54
74
A10AB05
ATC
insulin aspart; parenteral
3.4
37.3
146
467
A07AA11
ATC
rifaximin; oral
133.8
36.9
39
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
36.7
119
336
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
12.8
35.9
35
28
T90
ICPC
Diabetes non-insulin dependent
2.3
35.4
360
1869
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
35.2
200
791
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
356.3
35.1
35
*
L04AA01
ATC
[U] ciclosporin
8.3
33.9
45
56
K50.1
ICD-10 Finland
Crohn disease of large intestine
9.0
33.8
42
48
A10AE04
ATC
insulin glargine; parenteral
3.0
33.6
167
614
A10AC01
ATC
insulin (human); parenteral
3.2
33.4
140
466
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
13.1
33.2
32
25
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
9.3
33.1
40
44
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
32.4
31
*
JJA20
NOMESCO Finland
Open biopsy of liver
41.2
32.3
40
10
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
8.5
32.2
42
51
JJ5AT, ,
NOMESCO Finland
324.6
32.0
32
*
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
8.6
31.9
41
49
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.6
31.8
204
857
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.3
31.1
124
400
K50.8
ICD-10 Finland
Other Crohn disease
6.6
30.9
50
78
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
8.7
30.6
39
46
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
29.7
158
602
H02AB04
ATC
methylprednisolone; systemic
2.4
29.6
240
1122
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.8
29.6
169
668
R50.9
ICD-10 Finland
Fever, unspecified
2.4
28.3
234
1103
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
28.2
27
*
A10BG03
ATC
pioglitazone; oral
5.2
28.2
59
118
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
28.2
350
1944
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.6
27.1
66
150
J01MA12
ATC
levofloxacin; systemic
2.2
26.9
273
1400
K51.8
ICD-10 Finland
Other ulcerative colitis
6.3
26.7
45
73
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.2
26.7
111
367
A10BA02
ATC
metformin; oral
2.0
26.4
390
2297
A10BH01
ATC
sitagliptin; oral
2.7
26.2
152
605
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
25.9
162
669
K76.89
ICD-10 Finland
Other specified diseases of liver
265.6
25.8
26
*
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
10.2
25.7
29
29
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.3
25.5
43
70
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.5
25.4
186
827
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
24.4
215
1036
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
24.4
279
1493
B18.2
ICD-10 Finland
Chronic viral hepatitis C
7.2
24.2
36
51
UJK12
NOMESCO Finland
Peroral cholangioscopy
68.7
23.9
27
*
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
127.3
23.7
25
*
TK800
NOMESCO Finland
Hemodialysis
5.5
23.7
46
86
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
3.4
23.6
86
262
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
23.2
227
1142
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
55.1
23.1
27
5
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
+∞
23.0
22
*
K70.1
ICD-10 Finland
Alcoholic hepatitis
+∞
23.0
22
*
A10BJ06
ATC
semaglutide; parenteral
3.2
22.9
95
313
UJF92
NOMESCO Finland
Capsular endoscopy
5.0
22.9
49
100
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
85.0
22.7
25
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
22.5
159
694
K83.1
ICD-10 Finland
Obstruction of bile duct
6.8
22.2
35
53
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
21.6
229
1185
E66.01
ICD-10 Finland
Obesity due to excess calories
2.4
21.3
153
673
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
7.7
21.3
30
40
E66.00
ICD-10 Finland
Metabolic syndrome
3.0
21.2
99
350
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
6.3
20.7
35
57
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
20.6
256
1404
SPAT1262
SPAT
Handing over of treatment supplies
2.1
20.3
236
1264
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
20.0
356
2200
WX402
NOMESCO Finland
General anaesthesia
1.9
19.9
305
1795
UJD02
NOMESCO Finland
Gastroscopy
3.1
19.9
85
285
H02AB09
ATC
hydrocortisone; systemic
4.1
19.9
55
138
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
+∞
19.8
19
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.7
19.5
62
172
XW000
NOMESCO Finland
Bone marrow biopsy
3.4
19.5
73
226
K29.6
ICD-10 Finland
Other gastritis
6.2
19.4
33
54
Z2221
NOMESCO Finland
Medical doctor
1.8
19.4
381
2422
H26.3
ICD-10 Finland
Drug-induced cataract
8.5
19.3
25
30
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
19.0
155
720
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
18.6
143
647
K70.4
ICD-10 Finland
Alcoholic hepatic failure
192.6
18.6
19
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
5.9
18.4
33
57
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.0
18.4
81
277
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
18.3
117
486
K50.9
ICD-10 Finland
Crohn disease, unspecified
5.1
18.2
38
76
E66.8
ICD-10 Finland
Other obesity
2.8
17.8
94
355
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
67.5
17.8
20
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
17.7
170
843
K73.1
ICD-10 Finland
Chronic lobular hepatitis, not elsewhere classified
+∞
17.7
17
*
P01BA02
ATC
hydroxychloroquine; oral
2.4
17.7
133
596
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
3.3
17.5
66
205
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
17.3
329
2061
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
4.8
17.1
39
84
K75.8
ICD-10 Finland
Other specified inflammatory liver diseases
+∞
16.7
16
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
16.7
16
*
C07AA05
ATC
propranolol; systemic
1.8
16.5
295
1810
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
23.4
16.5
23
10
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
4.8
16.4
37
79
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.3
16.3
62
194
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
16.3
96
384
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.9
16.2
25
37
K70.0
ICD-10 Finland
Alcoholic fatty liver
48.1
16.0
19
*
WW500
NOMESCO Finland
Blood transfusion
3.1
16.0
67
222
R4190
NOMESCO Finland
Nutritional therapy
3.2
16.0
65
212
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
15.9
62
197
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
60.8
15.8
18
*
5719X
ICD-9 Finland
Chronic liver disease and cirrhosis, Unspecified chronic liver disease without mention of alcohol
+∞
15.7
15
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
15.5
476
3379
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.9
15.5
34
71
A07AA09
ATC
vancomycin; oral
5.8
15.4
28
49
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.8
15.4
47
127
P01AB01
ATC
metronidazole; oral, rectal
1.6
15.3
543
3989
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
7.1
15.3
23
33
Z3231
NOMESCO Finland
Registered nurse
1.7
15.3
352
2318
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
15.2
91
366
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.7
15.2
48
133
C07AG02
ATC
carvedilol; oral
2.6
15.2
87
343
A10BH05
ATC
linagliptin; oral
2.9
14.9
71
254
A10BJ02
ATC
liraglutide; parenteral
3.3
14.8
55
170
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
14.6
14
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
14.5
285
1792
K92.1
ICD-10 Finland
Melaena
2.8
14.3
72
265
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
14.2
199
1127
160
Kela drug reimbursment
exenatide
3.8
14.1
43
116
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
14.1
146
744
A07EA02
ATC
hydrocortisone; rectal
4.0
14.0
40
103
A02BC01
ATC
omeprazole; systemic
1.7
13.9
350
2352
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.8
13.9
71
264
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.8
13.9
42
113
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
53.9
13.8
16
*
N17.8
ICD-10 Finland
Other acute renal failure
6.3
13.8
23
37
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
12.2
13.6
24
20
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
75.9
13.6
15
*
K76.6
ICD-10 Finland
Portal hypertension
+∞
13.6
13
*
JN4CD
NOMESCO Finland
Very extensive body CT
3.2
13.5
53
169
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.1
13.3
36
89
WX002
NOMESCO Finland
Sedation and analgesia
1.7
13.3
254
1582
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
13.2
123
602
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
13.2
198
1147
J01FF01
ATC
clindamycin; systemic
1.6
13.1
351
2389
C08CA01
ATC
amlodipine; oral
1.6
13.0
462
3366
WX892
NOMESCO Finland
Monitored bed care
2.3
12.8
104
482
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
12.5
12
*
57300
ICD-8 Finland
Other diseases of liver, Hepatitis NUD
+∞
12.5
12
*
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
12.5
12
*
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
5.3
12.5
25
48
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
131.2
12.5
13
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
12.4
282
1839
E66.9
ICD-10 Finland
Obesity, unspecified
2.8
12.4
60
217
N02AA05
ATC
oxycodone; systemic
1.8
12.3
210
1262
WVA20
NOMESCO Finland
Medicine administration
3.3
12.3
46
143
A02BC03
ATC
lansoprazole; oral
1.6
12.2
375
2632
N30.0
ICD-10 Finland
Acute cystitis
1.8
12.2
207
1242
R4110
NOMESCO Finland
Physiotherapy
1.6
12.2
350
2417
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.8
12.0
60
221
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.9
11.9
26
54
RS220, ,
NOMESCO Finland
4.9
11.9
26
54
E0000UV, ,
ATC
1.5
11.9
523
3973
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.3
11.8
30
71
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
11.7
67
264
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
16.6
11.7
18
11
57309
ICD-8 Finland
Other diseases of liver, Unspecified
+∞
11.5
11
*
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
11.5
11
*
5714A
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA PERSISTENS]
+∞
11.5
11
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.3
11.4
85
379
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.1
11.4
108
532
K29.7
ICD-10 Finland
Gastritis, unspecified
2.8
11.3
56
205
WX704
NOMESCO Finland
Intubation
2.1
11.3
110
548
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
11.3
97
460
B01AB05
ATC
enoxaparin; parenteral
1.6
11.2
388
2792
M05BA04
ATC
alendronic acid; oral
2.1
11.1
113
571
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
11.1
67
271
A41.9
ICD-10 Finland
Sepsis, unspecified
3.1
11.1
46
152
Z94.0
ICD-10 Finland
Kidney transplant status
5.3
11.1
22
42
K86.2
ICD-10 Finland
Cyst of pancreas
5.3
11.1
22
42
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.1
11.1
107
531
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
11.1
88
404
A46
ICD-10 Finland
Erysipelas
1.8
11.0
169
982
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
11.0
374
2675
J01DB01
ATC
cefalexin; oral
1.6
11.0
1066
9494
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.9
10.9
31
80
L04AC05
ATC
ustekinumab; parenteral
15.6
10.8
17
11
ZXD05
NOMESCO Finland
Urgent procedure
1.6
10.8
366
2617
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
10.7
383
2769
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
10.7
81
364
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.8
10.7
175
1038
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.3
10.6
40
125
A10BK03
ATC
empagliflozin; oral
1.9
10.5
129
698
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
4.7
10.5
24
52
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.7
10.5
188
1145
Z3226
NOMESCO Finland
Physiotherapist
1.7
10.4
228
1465
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
10.4
10
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
5.5
10.4
20
37
N03AX16
ATC
[U] pregabalin
1.6
10.4
294
2015
5739X
ICD-9 Finland
Other disorders of liver, Unspecified disorder of liver
32.8
10.3
13
*
Z2446
NOMESCO Finland
Social worker
2.2
10.3
93
449
A10AE05
ATC
insulin detemir; parenteral
2.3
10.3
75
331
N05CF01
ATC
zopiclone; oral
1.5
10.3
391
2860
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
9.7
10.3
20
21
S97
ICPC
Chronic ulcer skin
2.3
10.2
77
345
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
10.2
65
270
ZX108
NOMESCO Finland
Inhalation
7.5
10.2
23
31
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
4.2
10.2
27
66
ZXE00
NOMESCO Finland
One hour or less
1.5
10.2
480
3670
N06AB04
ATC
citalopram; systemic
1.6
10.1
264
1774
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
3.6
10.1
33
94
WW200
NOMESCO Finland
Immunization
3.2
10.1
40
129
K81.9
ICD-10 Finland
Cholecystitis, unspecified
8.5
10.1
21
25
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
10.0
712
5882
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
10.0
113
595
JN4AD
NOMESCO Finland
Body CT examination
1.9
9.8
125
685
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.7
226
1473
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
9.7
163
972
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.4
9.7
22
30
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
9.7
58
234
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
9.7
72
321
RD210, ,
NOMESCO Finland
3.9
9.7
28
73
H03AA01
ATC
levothyroxine sodium; systemic
1.6
9.7
304
2129
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
9.7
464
3551
L04AB04
ATC
adalimumab; parenteral
3.2
9.7
38
122
AA1AD
NOMESCO Finland
CT of head and brain
1.5
9.6
308
2167
WX872
NOMESCO Finland
Intensive care
2.4
9.6
67
291
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
9.6
186
1157
M04AA01
ATC
allopurinol; systemic
1.9
9.6
134
757
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.3
9.6
69
304
K51
ICD-10 Finland
Ulcerative colitis
4.6
9.5
22
48
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.2
9.5
38
123
ZY010
NOMESCO Finland
Hospital outpatient
2.3
9.4
71
319
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
17.7
9.4
14
8
K74.2
ICD-10 Finland
Hepatic fibrosis with hepatic sclerosis
+∞
9.4
9
*
K75.3
ICD-10 Finland
Granulomatous hepatitis, not elsewhere classified
+∞
9.4
9
*
3A422, ,
NOMESCO Finland
+∞
9.4
9
*
K71.9
ICD-10 Finland
Toxic liver disease, unspecified
+∞
9.4
9
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.4
9.4
63
269
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
9.3
322
2302
3AC01, ,
NOMESCO Finland
7.3
9.2
21
29
A10BK01
ATC
dapagliflozin; oral
2.1
9.2
88
435
K65.0
ICD-10 Finland
Acute peritonitis
7.8
9.1
20
26
R11
ICD-10 Finland
Nausea and vomiting
1.9
9.1
108
578
N06AX11
ATC
mirtazapine; oral
1.5
9.0
417
3162
K90.0
ICD-10 Finland
Coeliac disease
2.7
8.8
47
179
205
Kela drug reimbursment
Chronic hypertension
1.5
8.8
278
1944
UKC02
NOMESCO Finland
Cystoscopy
1.7
8.7
165
1019
A02BC05
ATC
esomeprazole; systemic
1.4
8.7
505
3988
A10BX04
ATC
[U] exenatide
4.3
8.7
22
52
A41.8
ICD-10 Finland
Other specified sepsis
3.8
8.6
26
70
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
8.6
148
889
M81.8
ICD-10 Finland
Other osteoporosis
4.8
8.6
19
40
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
8.6
89
454
E83.1
ICD-10 Finland
Disorders of iron metabolism
10.1
8.5
16
16
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
8.5
183
1170
7904A
ICD-9 Finland
Nonspecific findings on examination of blood, Nonspecific elevation oflevels of transaminase or lactic acid dehydrogenase [LDH]
90.6
8.4
9
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.5
8.4
53
220
V03AE01
ATC
polystyrene sulfonate; oral
4.9
8.4
18
37
K73
ICD-10 Finland
Chronic hepatitis, not elsewhere classified
+∞
8.3
8
*
57308
ICD-8 Finland
Other diseases of liver, Alii definiti
+∞
8.3
8
*
K75.0
ICD-10 Finland
Abscess of liver
+∞
8.3
8
*
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
8.6
8.3
17
20
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.4
8.2
57
247
R74.9
ICD-10 Finland
Abnormal level of unspecified serum enzyme
14.6
8.2
13
9
L28
ICPC
Limited function/disability (L)
1.6
8.2
196
1285
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
7.6
8.2
18
24
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
8.1
95
506
UJF02
NOMESCO Finland
Peroral enteroscopy
9.0
8.0
16
18
A10BJ05
ATC
dulaglutide; parenteral
3.1
8.0
33
109
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
22.2
8.0
11
5
3042, ,
Kela drug reimbursment
22.2
8.0
11
5
253, ,
Kela drug reimbursment
22.2
8.0
11
5
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.9
437
3405
D64.8
ICD-10 Finland
Other specified anaemias
3.6
7.9
25
70
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
7.8
154
961
SPAT1255
SPAT
Intravenous administration of medicine
2.1
7.7
77
387
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
45.2
7.7
9
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.7
645
5388
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.3
7.7
55
242
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3.3
7.7
28
86
C08CA05
ATC
nifedipine; systemic
2.1
7.6
67
321
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.6
166
1062
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
18.5
7.6
11
6
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.9
7.6
35
124
R06AE07
ATC
cetirizine; oral
1.4
7.6
542
4409
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.7
7.6
38
141
M34.1
ICD-10 Finland
CR(E)ST syndrome
8.9
7.5
15
17
XG410
NOMESCO Finland
Flow-volume spirometry
2.3
7.5
54
238
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.9
7.5
97
534
A10AE06
ATC
insulin degludec; parenteral
2.4
7.5
49
207
C07AB07
ATC
bisoprolol; oral
1.4
7.5
547
4464
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
7.4
58
265
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.4
311
2299
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.4
7.4
26
78
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
6.0
7.4
19
32
JN4BD
NOMESCO Finland
Extensive body CT
1.8
7.4
119
702
R03AC02
ATC
salbutamol; inhalant
1.4
7.4
682
5775
Z72.1
ICD-10 Finland
Alcohol use
4.0
7.4
20
50
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
7.3
110
635
J01DA01
ATC
[U] cefalexin
1.4
7.3
760
6553
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
7.3
7
*
I86.4
ICD-10 Finland
Gastric varices
+∞
7.3
7
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
7.3
7
*
M35.1
ICD-10 Finland
Other overlap syndromes
9.4
7.3
14
15
WX882
NOMESCO Finland
High dependency care
2.8
7.3
35
127
JAH01
NOMESCO Finland
Laparoscopy
2.2
7.2
56
256
198
Kela drug reimbursment
Sorafenib
30.2
7.2
9
*
E000001, ,
ATC
1.5
7.1
233
1637
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
3.2
7.1
27
85
L01BB01, ,
ATC
20.1
7.1
10
5
A02BA02
ATC
ranitidine; systemic
1.5
7.1
224
1562
N05CD07
ATC
temazepam; oral
1.7
7.1
130
795
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.6
7.1
39
152
D07AC01
ATC
betamethasone; topical
1.4
7.1
425
3349
A10BX07
ATC
[U] liraglutide
3.5
7.0
23
66
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
7.0
86
467
N05BA04
ATC
oxazepam; oral
1.4
7.0
306
2280
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.9
365
2809
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
6.9
61
293
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
6.9
87
475
SPAT1104
SPAT
Monitoring of emergency patient
2.0
6.9
74
383
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.4
6.9
47
203
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.3
6.8
25
77
H25.8
ICD-10 Finland
Other senile cataract
1.8
6.8
109
641
D70.89
ICD-10 Finland
Neutropenic splenomegaly
3.8
6.8
20
53
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
6.7
6.8
16
24
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.5
6.8
42
173
N03AX12
ATC
[U] gabapentin; oral
1.5
6.8
200
1374
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
6.8
147
940
A99
ICPC
Disease/condition unspecnature/site
1.7
6.8
112
666
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.1
6.8
27
88
M13.9
ICD-10 Finland
Arthritis, unspecified
1.9
6.7
89
494
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.7
273
2004
0709X
ICD-9 Finland
Viral hepatitis, Unspecified viral hepatitis without mention of hepatic coma
22.6
6.7
9
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.7
314
2368
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.6
6.6
37
145
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.6
6.6
38
151
A10AB06
ATC
insulin glulisine; parenteral
4.0
6.6
18
45
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
6.6
34
128
N18.8
ICD-10 Finland
Other chronic renal failure
3.2
6.6
25
79
A07DA03
ATC
loperamide; oral
2.5
6.6
41
170
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
4.2
6.6
17
41
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.1
6.5
57
273
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
3.8
6.5
19
50
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
10.1
6.5
12
12
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
6.5
58
280
B03BA03
ATC
hydroxocobalamin; parenteral
2.1
6.5
59
287
N20.1
ICD-10 Finland
Calculus of ureter
2.4
6.5
42
177
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.6
6.5
35
135
N06AA09
ATC
amitriptyline; systemic
1.7
6.5
116
705
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.6
6.5
36
141
RS321, ,
NOMESCO Finland
70.2
6.4
7
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
6.4
81
444
K42.0
ICD-10 Finland
Umbilical hernia with obstruction, without gangrene
3.8
6.4
19
51
RS120, ,
NOMESCO Finland
8.2
6.3
13
16
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.3
109
656
R10.0
ICD-10 Finland
Acute abdomen
2.5
6.3
39
161
A03CA02
ATC
clidinium and psycholeptics; oral
2.0
6.3
65
332
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.3
260
1911
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.5
6.3
21
61
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
6.3
134
853
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
6.3
66
340
K71.5
ICD-10 Finland
Toxic liver disease with chronic active hepatitis
+∞
6.3
6
*
6615
FHL
Liver transplant
+∞
6.3
6
*
5718X
ICD-9 Finland
Chronic liver disease and cirrhosis, Other chronic nonalcoholic liver disease
+∞
6.3
6
*
K74.4
ICD-10 Finland
Secondary biliary cirrhosis
+∞
6.3
6
*
57001
ICD-8 Finland
Acute and subacute necrosis of liver, Hepatitis subacuta degenerativa
+∞
6.3
6
*
B01AB04
ATC
dalteparin; parenteral
2.1
6.2
58
285
N02BF02
ATC
pregabalin; oral
1.9
6.2
74
397
6611
FHL
Needle biopsy in the operating room
26.8
6.2
8
*
L04AA33
ATC
[U] vedolizumab
26.8
6.2
8
*
C03AA03
ATC
hydrochlorothiazide; oral
1.8
6.2
100
590
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
6.2
32
121
K85
ICD-10 Finland
Acute pancreatitis
3.4
6.2
21
62
D94
ICPC
Chronic enteritis/ulcerative colitis
5.8
6.1
16
28
B07.9
ICD-10 Finland
Verruca simplex
2.3
6.1
45
201
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.1
194
1353
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.4
6.1
40
170
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
12.6
6.1
10
8
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
12.6
6.1
10
8
JAH00
NOMESCO Finland
Laparotomy
2.5
6.1
37
152
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
3.6
6.0
19
53
K29
ICPC
Cardiovascular sympt/complt other
2.2
6.0
48
222
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.8
6.0
28
100
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
6.0
110
673

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
238
85
33.91
307.65
1.2
1.1
1.57
1.47
g/l
1.62
214
79
577
548
17.87
307.65
2.0
1.8
1.49
1.46
g/l
0.07
538
502
752
714
23.02
307.65
7.1
2.9
12.39
10.29
g/l
19.50
720
651
537
179
49.74
307.65
1.8
1.1
314.12
78.67
titre
3.07
102
15
700
862
16.08
307.65
5.7
1.9
0.21
0.22
g/l
2.73
662
815
346
40
116.69
307.65
1.7
1.2
—
—
—
0
0
570
1143
7.99
299.22
7.0
2.5
15.30
7.03
umol/l
5.82
525
986
1000
3503
8.54
295.62
10.9
3.0
48.65
30.04
u/l
24.09
974
3331
629
1420
7.52
293.43
2.0
1.3
784.00
526.11
titre
2.59
225
288
166
39
48.51
282.04
1.1
1.1
283.89
300.50
mg/l
0.68
147
34
162
40
46.00
271.88
1.2
1.0
—
—
—
0
0
1089
4429
9.16
265.43
12.2
4.3
35.67
36.02
g/l
1.33
1053
4116
155
41
42.68
255.48
1.1
1.0
—
—
—
0
0
523
1123
7.04
251.79
1.5
1.6
—
—
—
0
0
541
1276
6.47
234.30
2.6
2.3
25.68
22.54
%
3.58
466
1090
556
1376
6.24
227.81
2.5
2.3
2.43
2.36
g/l
1.61
524
1279
204
156
15.27
219.84
6.2
2.1
41.16
30.14
umol/l
4.50
196
135
1147
5503
9.03
214.89
17.3
5.7
15.19
10.58
umol/l
8.47
1128
5222
191
136
16.24
214.05
1.1
1.1
—
—
—
0
0
152
66
25.88
213.76
1.5
1.2
345.71
60.00
titre
—
42
9
196
147
15.47
213.41
1.1
1.1
—
—
—
0
0
561
1512
5.70
206.09
2.6
2.3
14.69
13.28
umol/l
3.30
535
1403
551
1481
5.65
202.58
1.5
1.6
—
—
—
0
0
182
134
15.58
199.94
2.0
1.7
0.71
0.88
g/l
0.50
142
99
643
2125
4.93
180.54
2.1
1.4
2.98
2.22
g/l
14.14
526
1258
993
4614
5.59
178.97
16.5
12.7
1.13
1.22
inr
3.63
315
1322
721
2658
4.75
174.44
12.3
3.5
91.18
93.02
%
1.10
704
2590
982
5034
4.66
141.90
14.3
6.2
—
—
—
0
0
1005
5350
4.63
134.94
13.8
5.7
0.04
0.04
e9/l
0.19
927
4645
1004
5342
4.62
134.87
13.8
5.7
0.56
0.57
e9/l
0.66
924
4639
1014
5535
4.54
128.79
14.0
6.0
0.18
0.19
e9/l
1.17
938
4880
1008
5502
4.47
127.44
13.9
5.7
1.71
1.91
e9/l
7.44
934
4884
936
4856
4.15
127.32
14.1
5.8
0.74
0.69
%
2.38
915
4529
951
5018
4.17
125.43
14.1
5.8
2.88
2.87
%
0.04
928
4693
159
192
9.27
124.39
1.4
1.2
—
—
—
0
0
952
5045
4.14
124.31
14.6
6.1
9.05
8.52
%
5.91
929
4725
950
5127
4.01
118.30
14.0
5.6
56.91
56.66
%
0.28
927
4809
956
5199
4.01
117.25
14.4
5.8
28.07
28.50
%
0.64
933
4882
153
196
8.69
113.96
1.2
1.4
—
—
—
0
0
151
197
8.52
110.73
1.3
1.2
362.90
247.33
u/ml
2.43
86
115
81
39
22.06
108.36
28.3
29.9
6.55
7.33
ug/l
1.20
74
33
867
4568
3.59
108.31
3.7
2.2
74.50
77.34
nmol/l
2.36
814
4105
702
3270
3.44
106.78
4.8
2.4
59.55
59.18
u/l
0.04
669
3032
196
365
6.13
103.14
4.5
3.2
345.28
3807.51
u/ml
0.70
175
320
1038
6279
4.01
101.31
17.0
8.9
3.72
4.03
e9/l
5.85
958
5501
137
183
8.23
98.28
1.3
1.4
108.15
105.65
u/ml
0.09
24
35
1216
8379
6.44
95.70
24.6
7.0
100.68
76.18
u/l
35.50
1197
7889
175
327
6.01
91.42
1.4
1.3
—
—
—
0
0
57
16
37.18
91.35
3.5
1.3
—
—
—
0
0
420
1557
3.48
89.79
2.6
2.1
30.38
29.45
s
2.24
405
1509
1115
7386
4.20
87.89
10.3
2.8
120.26
43.70
u/l
34.79
1072
6904
271
762
4.21
86.76
1.3
1.4
—
—
—
0
0
68
37
19.32
86.05
4.5
2.1
—
—
—
0
0
122
174
7.62
82.45
1.2
1.2
—
—
—
0
0
275
828
3.93
79.60
11.3
6.9
8.88
8.95
mmol/l
0.06
264
784
879
5222
3.03
79.03
9.3
6.5
1.21
1.22
mmol/l
0.51
767
4430
66
43
16.10
76.42
33.0
30.4
116.97
133.06
ug/l
0.69
59
33
534
2479
2.93
75.43
1.5
1.2
1.37
1.67
u/ml
0.38
124
656
810
4693
2.87
74.68
3.8
2.7
209.90
112.57
ug/l
6.37
767
4346
297
981
3.61
74.63
3.8
2.2
33.80
35.48
u/l
0.29
268
840
289
938
3.66
74.58
1.5
1.4
—
—
—
0
0
815
4767
2.84
73.25
7.6
5.8
1.21
1.22
mmol/l
0.75
772
4325
143
284
5.52
69.49
4.8
3.3
1.57
1.45
mg/l
0.85
134
263
44
14
32.47
67.81
3.2
1.4
—
—
—
0
0
601
3109
2.71
67.15
4.8
3.9
7.40
7.40
ph
0.13
107
580
523
2564
2.72
64.49
2.9
2.1
3.08
2.95
mg/l
0.57
470
2175
383
1680
2.80
57.69
4.4
3.3
0.79
0.82
mmol/l
4.86
362
1577
1101
8074
3.14
56.09
8.3
4.0
17.80
11.63
mm/h
26.90
1046
7473
331
1375
2.88
54.96
3.5
2.2
149.11
110.92
ug/g
1.89
288
1075
159
421
4.16
54.07
1.9
1.5
4.68
11.04
u/ml
0.99
14
11
270
1015
3.08
53.56
4.3
4.1
3.04
21.57
ug/l
2.32
225
826
316
1309
2.86
52.50
7.4
5.2
1.05
1.04
mmol/l
0.39
304
1210
40
20
20.59
52.25
2.2
1.5
4031.14
4704.09
e6/l
0.07
22
11
899
6152
2.43
49.10
8.3
4.6
7.13
6.64
mmol/l
5.01
870
5734
224
795
3.19
48.74
6.1
3.9
0.88
0.66
%
0.22
90
251
44
31
14.65
48.65
1.8
4.5
—
—
—
0
0
66
88
7.84
47.00
1.4
1.3
3.12
2.53
g/l
1.35
36
60
66
88
7.84
47.00
1.4
1.3
0.50
0.28
g/l
3.30
37
61
66
88
7.84
47.00
1.4
1.3
9.83
6.55
g/l
2.69
36
62
235
875
3.05
46.99
6.6
3.9
0.68
0.96
%
1.43
102
293
67
91
7.70
46.96
1.4
1.3
—
—
—
0
0
582
3361
2.30
46.69
3.4
2.3
—
—
—
0
0
253
992
2.92
46.04
2.2
2.1
356.29
375.42
nmol/l
0.42
237
914
213
778
3.07
43.87
6.7
4.1
0.16
0.54
%
0.39
75
199
739
4797
2.22
43.57
19.4
9.0
0.00
0.00
e9/l
0.95
641
3927
498
2772
2.28
42.76
11.8
6.6
—
—
—
0
0
88
176
5.28
42.11
3.9
3.7
42.16
2017.67
u/ml
0.78
83
167
469
2579
2.27
41.16
3.3
2.2
—
—
—
0
0
45
44
10.55
40.61
2.4
2.7
39972.69
38368.30
ug/l
0.25
45
44
477
2666
2.23
40.01
6.2
4.1
—
—
—
0
0
314
1469
2.49
39.71
2.9
2.0
—
—
—
0
0
34
22
15.83
39.24
2.5
1.6
—
—
—
0
0
211
829
2.84
37.79
6.9
4.0
0.03
0.13
%
2.81
77
247
39
35
11.45
37.24
1.0
1.1
—
—
—
0
0
39
36
11.13
36.55
1.0
1.0
—
—
—
0
0
315
1536
2.38
35.97
1.3
1.2
—
—
—
0
0
38
37
10.54
34.34
1.8
1.4
10.71
8.40
ug/l
1.73
38
37
241
1062
2.55
34.17
3.0
2.9
2.17
1.79
%
4.63
231
951
131
415
3.39
33.88
2.0
2.0
1.19
1.55
g/l
3.88
118
366
42
11
39.39
33.55
1.7
1.1
17.06
16.87
umol/l
0.06
35
11
192
777
2.72
32.24
2.7
2.8
76.78
72.35
e9/l
0.81
161
589
103
292
3.74
31.49
1.5
1.2
33.45
2.76
u/ml
0.54
17
27
730
5086
1.97
31.46
3.7
2.5
—
—
—
0
0
104
297
3.71
31.46
1.5
1.2
9.75
5.24
u/ml
0.75
30
45
208
889
2.59
31.25
1.2
1.2
—
—
—
0
0
256
1208
2.39
31.06
1.9
1.3
—
—
—
0
0
637
4263
1.95
30.64
2.3
1.9
96.90
96.29
pmol/l
0.10
340
2143
104
316
3.49
28.63
1.5
1.2
44.69
32.35
u/ml
0.24
14
19
201
880
2.51
28.59
5.1
3.4
5.65
5.86
kpa
2.56
192
851
199
873
2.51
28.16
5.0
3.4
1.34
1.96
mmol/l
1.51
169
724
63
135
4.85
27.79
1.6
1.3
40.78
58.60
u/ml
—
6
6
58
118
5.09
27.17
3.1
2.2
21.51
5.41
umol/l
1.57
47
76
449
2761
1.95
26.90
3.8
2.5
1733.77
5319.81
umol/l
2.23
404
2428
511
3282
1.91
26.84
3.9
3.1
7.14
7.54
mmol/l
1.32
443
2799
302
1626
2.11
26.15
3.4
2.8
2.67
2.62
e6/l
0.04
180
860
498
3208
1.88
25.64
3.9
2.9
—
—
—
0
0
476
3031
1.89
25.34
4.0
3.2
164.87
288.68
mg/l
0.50
326
1883
32
38
8.60
24.95
1.1
1.2
—
—
—
0
0
483
3119
1.86
24.40
4.4
3.1
40.44
74.26
e6/l
0.73
389
2374
490
3179
1.86
24.39
4.6
3.8
12.50
7.10
mg/mmol
1.10
328
1954
446
2809
1.89
24.37
4.2
2.9
—
—
—
0
0
79
224
3.69
24.11
1.6
2.2
1.06
0.84
nmol/l
1.64
66
186
330
1889
1.99
23.91
1.7
1.8
—
—
—
0
0
449
2848
1.87
23.90
4.3
2.9
0.32
0.41
e6/l
0.68
354
2131
349
2038
1.97
23.87
3.7
2.7
523.44
535.24
mosm/kgh2o
0.48
308
1755
308
1724
2.02
23.76
3.3
2.6
1.05
1.06
e6/l
0.02
185
957
1244
11006
3.11
23.70
31.0
12.8
17.14
22.74
mg/l
11.82
1115
8543
936
7432
1.88
23.61
6.3
4.2
—
—
—
0
0
53
113
4.84
23.51
1.2
1.3
—
—
—
0
0
55
121
4.70
23.51
2.3
2.5
—
—
—
0
0
630
4447
1.79
23.50
2.3
2.1
—
—
—
0
0
176
798
2.39
22.96
9.7
8.5
—
—
—
0
0
71
195
3.79
22.69
5.0
3.5
3.97
4.21
e9/l
0.32
71
195
541
3685
1.79
22.49
5.1
3.6
89.89
84.87
e6/l
0.07
406
2537
894
7050
1.82
22.42
5.9
4.2
94.71
2412.57
e6/l
—
7
97
354
2136
1.90
21.66
3.4
2.5
5.86
6.25
e6/l
0.21
317
1919
71
202
3.66
21.56
5.3
3.8
57.48
57.78
%
0.07
71
202
170
781
2.35
21.47
1.6
3.1
69.25
67.06
g/l
2.19
156
719
28
34
8.39
21.43
1.1
1.2
—
—
—
0
0
112
427
2.77
20.85
1.6
1.2
4.04
1.07
u/ml
—
5
37
77
239
3.36
20.47
1.6
1.2
40.21
48.84
u/ml
0.25
19
25
380
2397
1.82
19.94
1.7
1.5
18.78
21.06
nmol/l
2.40
345
2044
465
3198
1.70
17.61
2.6
2.1
353.51
210.00
u/l
0.42
444
3018
164
809
2.17
17.34
3.7
3.5
85.14
80.46
ng/l
0.29
151
718
39
84
4.75
17.12
1.3
1.1
—
—
—
0
0
143
678
2.24
16.65
1.5
2.7
—
—
—
0
0
1244
11320
2.60
16.52
30.2
14.4
139.14
139.73
mmol/l
14.62
1228
11014
136
634
2.28
16.49
4.1
3.4
7.42
7.41
ph
0.74
23
86
294
1806
1.81
16.41
2.0
1.7
1093.12
1195.55
nmol/l
1.14
238
1352
218
1219
1.94
16.33
2.1
1.6
—
—
—
0
0
137
644
2.26
16.28
4.1
3.3
4.99
5.16
kpa
1.71
128
620
684
5278
1.61
15.95
4.5
3.6
0.00
0.00
estimate
-0.00
149
1045
1244
11353
2.55
15.81
30.5
14.6
3.93
3.96
mmol/l
2.48
1229
11024
224
1301
1.87
14.86
1.9
1.4
—
—
—
0
0
679
5296
1.58
14.64
6.1
4.8
0.01
0.00
estimate
0.40
139
992
182
992
1.97
14.61
9.1
8.6
95.63
95.85
%
0.19
176
957
683
5350
1.57
14.34
4.5
3.6
0.01
0.01
estimate
0.05
134
957
565
4248
1.58
14.13
3.9
3.3
5.94
5.77
ph
0.57
35
327
144
736
2.07
13.80
2.2
2.9
6.55
5.96
e9/l
0.10
122
602
197
1129
1.87
13.56
8.6
8.0
4.90
5.13
kpa
2.92
192
1076
45
129
3.58
13.56
1.4
1.2
—
—
—
0
0
112
522
2.25
13.56
10.5
11.6
—
—
—
0
0
80
321
2.59
13.47
3.0
3.2
—
—
—
0
0
37
93
4.06
13.41
1.4
1.9
1.27
1.27
e9/l
0.01
31
85
76
300
2.63
13.23
1.4
1.4
278.39
307.39
ug/g
0.56
49
175
493
3641
1.56
13.05
3.0
3.3
2.35
2.36
mmol/l
0.61
432
3209
26
28
9.45
12.99
1.1
1.1
—
—
—
0
0
140
725
2.04
12.94
4.0
2.8
4.94
4.48
kpa
1.19
131
698
40
110
3.72
12.81
1.3
1.1
—
—
—
0
0
34
83
4.18
12.81
1.1
1.1
—
—
—
0
0
194
1126
1.85
12.80
8.7
8.0
0.62
1.13
mmol/l
0.88
151
904
357
2457
1.62
12.70
4.1
3.5
—
—
—
0
0
158
869
1.93
12.29
8.4
7.2
1.66
1.28
mmol/l
3.07
153
843
29
65
4.54
12.16
1.1
2.0
0.18
0.21
e9/l
0.29
23
58
21
17
12.53
12.13
1.6
1.5
—
—
—
0
0
1082
9625
1.67
11.74
36.0
15.4
15.40
14.82
%
2.58
1077
9440
99
468
2.21
11.58
4.4
3.4
—
—
—
0
0
29
68
4.34
11.51
1.1
2.0
566.35
574.25
e6/l
0.02
23
59
49
169
2.97
11.01
1.2
1.3
54.74
60.84
mmol/l
0.61
39
148
150
841
1.88
10.98
4.2
3.4
1.22
1.23
mmol/l
0.95
140
719
392
2849
1.53
10.71
2.7
2.9
1674.77
1032.64
ng/l
0.91
326
2370
349
2473
1.56
10.69
2.1
1.7
1.74
1.00
mg/l
3.25
279
1871
70
300
2.41
10.30
2.2
2.2
11.60
11.68
mg/l
0.03
64
273
136
755
1.89
10.25
2.7
2.8
146.95
170.41
ng/l
0.43
127
684
33
94
3.57
10.08
2.9
3.3
60.54
54.52
%
0.81
28
82
406
3014
1.50
9.90
1.9
1.7
1.52
1.40
mmol/l
1.49
363
2545
113
597
1.98
9.86
1.6
1.2
—
—
—
0
0
175
1063
1.74
9.82
6.8
3.9
—
—
—
0
0
57
228
2.57
9.71
2.4
3.0
8.77
8.21
kpa
1.36
57
223
289
2008
1.56
9.53
1.4
1.3
41.61
31.17
iu/ml
0.75
99
660
78
364
2.21
9.44
3.6
3.4
0.31
0.26
g/l
0.22
35
140
314
2227
1.54
9.43
1.7
1.6
105364449.02
26228162.27
pmol/l
0.62
261
1853
44
159
2.83
9.13
2.0
1.6
—
—
—
0
0
22
50
4.46
9.10
2.5
3.0
2820.18
1064.36
u/ml
0.64
22
50
53
213
2.55
8.96
2.3
2.2
125.44
131.08
g/l
0.80
41
159
66
296
2.29
8.80
1.6
4.1
37.30
56.21
mg/l
0.44
57
248
66
296
2.29
8.80
1.6
4.1
43.13
63.60
mg/l
0.48
58
248
33
104
3.23
8.67
1.2
1.1
—
—
—
0
0
70
325
2.22
8.60
2.3
2.2
734.12
273.33
ug/l
0.59
65
303
86
433
2.05
8.59
2.3
2.0
22.65
21.18
s
2.49
79
384
279
1964
1.53
8.59
3.6
3.6
162.92
409.54
ng/l
2.53
214
1461
1111
10159
1.58
8.46
8.1
5.4
41.28
39.43
mmol/mol
6.67
1060
9449
1253
11842
2.06
8.44
29.9
9.8
43.55
26.15
u/l
54.48
1242
11438
1115
10209
1.58
8.38
5.6
4.8
1.92
2.00
mu/l
0.31
1053
9396
18
37
4.92
8.37
1.7
2.2
63.29
108.67
umol/l
—
7
24
81
405
2.07
8.25
5.1
3.6
24.00
25.03
mmol/l
2.25
76
382
968
8619
1.46
8.24
4.5
4.1
14.80
14.73
pmol/l
0.37
906
7874
67
313
2.20
8.12
6.1
7.9
1.44
1.32
mmol/l
0.39
60
278
78
389
2.07
8.01
2.5
2.0
1.16
1.68
ug/l
0.29
71
345
45
178
2.58
7.89
2.4
2.5
—
—
—
0
0
496
3967
1.40
7.70
4.2
3.4
35.00
46.54
ng/l
0.50
361
2631
268
1911
1.50
7.69
1.4
1.3
15.43
11.22
u/ml
0.38
81
753
207
1397
1.57
7.64
1.3
1.3
—
—
—
0
0
46
191
2.46
7.32
5.5
3.1
—
—
—
0
0
89
482
1.91
7.26
2.3
1.8
—
—
—
0
0
87
468
1.92
7.24
1.1
1.2
—
—
—
0
0
61
288
2.17
7.23
1.6
4.1
0.92
1.29
ratio
—
6
28
34
122
2.83
7.20
1.1
1.2
—
—
—
0
0
68
346
2.02
6.65
1.6
2.7
14.88
10.19
g/l
5.29
62
319
107
641
1.73
6.30
5.0
5.4
—
—
—
0
0
48
221
2.22
6.09
1.5
4.3
—
—
—
0
0
25
83
3.05
6.09
2.0
1.3
1.03
1.31
promille
0.35
18
68
45
202
2.27
6.07
3.0
2.4
16.78
16.36
%
0.30
30
105
48
223
2.20
5.97
1.3
1.8
—
—
—
0
0
58
297
2.00
5.62
1.5
2.7
38.17
38.57
g/l
0.19
52
271
43
199
2.20
5.42
6.3
3.2
3.23
2.58
mmol/l
0.78
29
132
26
96
2.74
5.28
1.2
1.3
—
—
—
0
0
382
3090
1.33
5.07
4.2
3.6
—
—
—
0
0
1143
10766
1.45
5.07
5.9
4.4
6.25
5.88
mmol/l
10.65
1077
9850
37
166
2.26
5.04
1.2
1.4
—
—
—
0
0
1129
10617
1.43
4.99
4.9
3.9
1.41
1.30
mmol/l
4.22
1063
9774
351
2810
1.34
4.99
5.0
3.9
0.01
0.01
estimate
0.05
139
968
28
113
2.51
4.81
2.7
3.9
—
—
—
0
0
360
2911
1.32
4.75
4.0
3.2
—
—
—
0
0
1168
11075
1.46
4.72
5.6
4.3
4.58
4.75
mmol/l
6.72
1108
10309
14
30
4.70
4.68
1.8
1.6
—
—
—
0
0
337
4122
0.76
4.66
3.4
2.7
—
—
—
0
0
27
109
2.51
4.64
1.7
2.3
33.37
32.50
pg
0.52
27
109
69
1136
0.59
4.55
1.3
1.3
—
—
—
0
0
38
737
0.50
4.39
1.6
1.4
—
—
—
0
0
38
184
2.10
4.34
1.9
1.4
—
—
—
0
0
370
3043
1.30
4.25
1.5
1.4
—
—
—
0
0
290
2309
1.33
4.21
4.8
3.9
1.02
1.02
kg/l
0.08
52
334
8
10
8.04
4.06
1.3
1.0
—
—
—
0
0
46
246
1.90
4.01
6.1
3.0
7.43
7.42
ph
0.31
41
216
14
36
3.92
4.00
1.2
1.3
—
—
—
0
0
25
105
2.41
3.99
2.8
2.5
—
—
—
0
0
1179
11263
1.42
3.94
6.0
4.8
2.69
2.82
mmol/l
5.21
1110
10431
14
37
3.81
3.90
1.6
1.6
—
—
—
0
0
11
23
4.81
3.87
1.2
1.1
—
—
—
0
0
244
1917
1.33
3.86
2.7
2.9
2.47
2.45
mmol/l
1.42
212
1675
1156
11013
1.39
3.86
5.5
4.3
1.40
1.49
mmol/l
9.12
1091
10197
42
221
1.93
3.85
1.4
1.4
—
—
—
0
0
7
8
8.79
3.77
1.0
1.1
—
—
—
0
0
16
55
2.93
3.74
1.4
1.9
—
—
—
0
0
119
837
1.46
3.63
2.0
2.3
5.63
7.49
ug/l
0.91
106
739
10
21
4.79
3.56
1.3
1.4
-1.27
1.94
mmol/l
—
10
21
26
118
2.23
3.52
1.7
2.2
—
—
—
0
0
57
340
1.71
3.52
1.3
1.1
—
—
—
0
0
49
280
1.78
3.51
3.3
2.4
—
—
—
0
0
56
333
1.71
3.50
1.3
1.3
237.50
238.07
miu/ml
0.00
22
160
15
52
2.91
3.47
4.4
2.5
—
—
—
0
0
13
37
3.54
3.40
1.0
1.0
—
—
—
0
0
24
108
2.24
3.33
1.3
1.5
—
—
—
0
0
44
248
1.80
3.31
1.2
1.2
4.23
3.82
mmol/l
0.50
39
233
100
694
1.48
3.28
3.7
2.7
—
—
—
0
0
58
355
1.66
3.28
2.0
2.6
—
—
—
0
0
12
34
3.55
3.20
1.9
1.6
—
—
—
0
0
44
251
1.78
3.19
2.1
2.3
107.83
83.50
ug/min
0.25
26
146
1202
11586
1.40
3.19
27.0
12.0
—
—
—
0
0
14
50
2.82
3.09
1.2
1.2
—
—
—
0
0
11
30
3.69
3.09
1.2
1.1
—
—
—
0
0
13
41
3.19
3.06
1.2
1.0
1742.08
1685.88
miu/ml
0.05
13
41
106
757
1.44
3.02
1.3
1.3
—
—
—
0
0
20
87
2.32
3.01
2.2
1.6
7.81
6.71
mmol/l
0.77
12
54
50
303
1.68
2.96
1.1
1.2
—
—
—
0
0
13
46
2.84
2.92
1.5
2.3
65.92
60.95
ug/l
0.11
13
46
26
129
2.04
2.87
4.4
2.6
—
—
—
0
0
123
911
1.39
2.86
5.0
3.7
—
—
—
0
0
23
109
2.13
2.85
1.4
1.2
—
—
—
0
0
34
186
1.85
2.85
1.4
1.6
—
—
—
0
0
24
116
2.09
2.84
1.1
1.1
—
—
—
0
0
25
123
2.05
2.82
1.2
1.4
—
—
—
0
0
10
28
3.59
2.78
1.1
1.9
248.00
214.12
e6/l
—
5
17
75
510
1.50
2.76
4.7
3.3
—
—
—
0
0
17
72
2.38
2.73
1.2
1.3
—
—
—
0
0
25
125
2.02
2.72
1.8
1.5
—
—
—
0
0
6
10
6.02
2.70
1.0
1.1
—
—
—
0
0
12
43
2.81
2.65
2.2
3.5
—
—
—
0
0
23
114
2.04
2.57
4.1
3.1
—
—
—
0
0
96
697
1.41
2.53
2.3
2.2
13.54
12.88
nmol/l
0.29
85
630
22
108
2.05
2.52
1.0
1.1
—
—
—
0
0
146
1137
1.32
2.48
1.6
1.5
—
—
—
0
0
13
51
2.56
2.44
5.8
3.3
8.99
10.35
mmol/l
0.62
13
51
6
12
5.02
2.40
1.2
1.5
—
—
—
0
0
9
28
3.23
2.31
1.2
1.7
—
—
—
0
0
33
193
1.73
2.28
4.2
2.6
—
—
—
0
0
41
635
0.63
2.20
1.7
1.7
—
—
—
0
0
15
67
2.25
2.18
1.3
1.3
—
—
—
0
0
51
339
1.52
2.14
4.2
3.8
1.44
1.27
mmol/l
0.68
51
332
38
237
1.62
2.09
1.4
1.4
45.71
12.98
e6/l
0.72
28
188
38
237
1.62
2.09
1.6
1.4
12263.93
924.22
e6/l
0.48
30
195
50
334
1.52
2.06
2.3
2.1
10941.68
2751.75
u/l
0.56
17
134
823
7733
1.17
2.05
3.9
3.6
—
—
—
0
0
14
63
2.24
2.01
1.3
1.1
1.08
1.06
ratio
—
5
20
21
113
1.87
1.92
2.7
2.8
1.36
1.46
g/24h
—
10
59
108
841
1.31
1.88
4.4
3.2
—
—
—
0
0
8
28
2.87
1.86
5.0
6.3
22.81
25.95
mmol/l
—
8
28
61
435
1.42
1.84
1.0
1.1
—
—
—
0
0
72
529
1.38
1.84
2.5
2.4
—
—
—
0
0
5
12
4.18
1.82
2.0
2.0
—
—
—
0
0
33
207
1.61
1.81
2.7
3.2
—
—
—
0
0
24
138
1.75
1.80
1.0
1.2
—
—
—
0
0
1261
12380
1.38
1.77
45.0
18.9
236.01
254.96
e9/l
15.42
1249
12082
26
154
1.70
1.77
5.5
3.0
—
—
—
0
0
53
373
1.44
1.73
5.4
4.3
—
—
—
0
0
8
30
2.68
1.72
1.4
1.3
—
—
—
0
0
15
75
2.01
1.70
2.4
3.6
8.60
11.04
%
1.38
15
75
1260
12376
1.36
1.69
45.0
19.0
39.80
40.67
%
1.39
1186
11614
1261
12388
1.37
1.68
44.6
18.8
91.75
90.85
fl
8.32
1252
12214
1261
12388
1.37
1.68
44.9
18.9
6.52
6.61
e9/l
0.83
1246
12055
57
411
1.40
1.65
1.6
1.6
—
—
—
0
0
15
76
1.98
1.64
1.1
1.1
—
—
—
0
0
1261
12394
1.36
1.62
45.1
19.0
133.55
135.77
g/l
5.68
1252
12221
15
77
1.96
1.59
4.7
3.5
—
—
—
0
0
1260
12389
1.34
1.55
44.6
18.8
30.52
30.26
pg
4.61
1251
12213
1260
12390
1.34
1.54
44.9
18.9
4.42
4.51
e12/l
7.72
1245
12053
25
153
1.65
1.54
1.1
1.0
4.37
2.07
u/ml
—
7
71
26
161
1.63
1.53
1.5
1.4
—
—
—
0
0
90
706
1.29
1.53
1.4
1.3
153.14
225.23
u/ml
0.71
83
651
7
27
2.60
1.51
1.1
1.1
—
—
—
0
0
11
51
2.17
1.50
1.4
1.4
—
—
—
0
0
10
200
0.50
1.42
1.2
1.4
—
—
—
0
0
10
199
0.50
1.40
1.2
1.4
—
—
—
0
0
12
60
2.01
1.38
2.6
2.1
500.43
506.00
min
—
7
45
0
37
0.00
1.34
0.0
1.2
—
33.64
—
0
28
11
207
0.53
1.32
1.2
1.4
—
—
—
0
0
36
250
1.45
1.31
1.6
1.7
14747.26
14304.89
e6/l
0.03
23
194
40
284
1.42
1.30
1.5
1.7
52.81
38.43
nmol/l
1.24
40
272
6
24
2.51
1.30
1.8
1.3
—
—
—
0
0
87
696
1.27
1.30
1.5
1.3
30.72
43.84
au/ml
—
6
45
40
285
1.42
1.28
1.5
1.3
9.51
10.16
u/l
0.14
31
226
8
35
2.29
1.27
1.3
1.1
—
—
—
0
0
23
146
1.59
1.26
2.1
1.8
—
—
—
0
0
6
25
2.41
1.24
1.5
1.2
—
—
—
0
0
95
773
1.25
1.24
2.8
2.4
25.98
23.00
au/ml
—
6
68
5
19
2.64
1.21
1.0
1.1
—
—
—
0
0
8
38
2.11
1.18
4.3
2.3
—
—
—
0
0
87
709
1.24
1.14
2.6
3.4
4.40
4.57
pmol/l
0.79
81
622
18
111
1.63
1.12
1.4
1.4
282.77
278.38
mosm/kgh2o
0.30
13
79
27
184
1.48
1.11
1.5
1.2
5.00
5.22
u/ml
0.03
18
68
5
22
2.28
1.03
2.0
1.9
—
—
—
0
0
13
75
1.74
1.03
1.9
1.5
76.08
79.19
umol/l
0.18
13
75
17
107
1.60
1.00
1.2
2.3
—
—
—
0
0
9
49
1.84
0.98
3.1
3.3
—
—
—
0
0
13
78
1.67
0.91
1.5
1.6
—
—
—
0
0
17
111
1.54
0.88
1.5
2.4
—
—
—
0
0
8
43
1.87
0.87
1.1
1.1
—
—
—
0
0
12
192
0.62
0.86
1.4
1.6
—
—
—
0
0
6
31
1.94
0.84
1.0
1.0
—
—
—
0
0
8
45
1.78
0.84
1.1
1.2
—
—
—
0
0
38
293
1.31
0.82
1.5
2.0
4.36
4.87
iu/l
0.11
11
104
10
58
1.73
0.79
1.3
2.9
2359.00
2015.67
ml
—
10
52
28
209
1.35
0.76
8.5
2.8
1.66
1.50
mmol/l
0.28
28
204
5
24
2.09
0.74
2.0
3.5
—
—
—
0
0
7
38
1.85
0.73
3.9
1.6
—
—
—
0
0
5
25
2.00
0.72
4.0
7.5
—
—
—
0
0
33
257
1.29
0.69
7.1
4.2
—
—
—
0
0
13
189
0.68
0.64
1.2
1.1
0.42
2.36
u/ml
—
6
106
8
49
1.64
0.62
1.0
1.9
—
—
—
0
0
142
1569
0.89
0.61
2.5
2.9
0.68
0.75
ug/l
0.39
95
986
8
52
1.54
0.59
1.1
1.3
200.37
177.20
mmol/24h
—
8
52
18
131
1.38
0.59
1.1
1.2
—
—
nmol/l
—
0
0
8
53
1.51
0.58
1.0
1.2
115.75
148.53
nmol/l
—
8
53
92
813
1.14
0.57
1.3
1.2
176.21
132.35
iu/ml
0.52
32
327
15
107
1.41
0.55
1.5
1.5
—
—
—
0
0
86
971
0.88
0.54
1.6
1.6
—
—
—
0
0
9
61
1.48
0.53
1.3
1.3
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
88
781
1.14
0.52
1.5
1.4
—
—
—
0
0
35
287
1.23
0.51
1.4
1.5
122.35
216.31
pmol/l
0.81
35
282
6
40
1.50
0.51
3.2
12.3
—
—
—
0
0
17
223
0.76
0.48
3.4
3.7
43.42
21.21
mg/l
1.22
12
136
7
47
1.49
0.47
4.1
3.0
—
—
—
0
0
23
182
1.27
0.46
4.0
3.0
0.81
0.84
nmol/l
0.08
15
148
23
182
1.27
0.46
1.4
1.2
—
—
—
0
0
17
221
0.77
0.46
4.2
3.7
19.82
33.04
u/ml
1.27
17
215
13
94
1.39
0.46
1.3
1.1
—
—
—
0
0
57
498
1.15
0.44
1.4
1.3
33.99
29.29
iu/l
0.38
46
419
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
15
191
0.78
0.37
1.1
1.1
—
—
—
0
0
23
189
1.22
0.36
1.1
1.1
—
10.28
—
0
13
15
190
0.79
0.35
1.1
1.1
—
—
—
0
0
6
45
1.33
0.33
1.2
2.1
27.62
192.95
ug/l
—
6
40
13
161
0.81
0.27
1.2
1.1
0.00
2.06
u/ml
—
5
87
34
300
1.14
0.26
1.1
1.1
—
—
—
0
0
9
72
1.25
0.25
1.1
1.6
4.56
8.32
ug/l
—
9
58
14
169
0.83
0.24
1.0
1.1
3.06
3.78
u/ml
—
8
93
14
168
0.83
0.23
1.1
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
53.18
—
0
11
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
38
347
1.10
0.18
8.7
8.9
—
—
—
0
0
31
280
1.11
0.18
1.5
2.3
—
—
—
0
0
44
406
1.09
0.18
1.8
1.7
—
—
—
0
0
7
62
1.13
0.17
1.0
1.2
—
—
—
0
0
131
1258
1.05
0.17
1.6
1.7
—
—
—
0
0
5
69
0.72
0.17
1.2
1.4
1.61
1.59
g/l
—
5
69
14
120
1.17
0.16
1.3
1.6
—
—
—
0
0
8
70
1.14
0.16
2.9
2.0
—
—
—
0
0
8
72
1.11
0.16
1.1
1.0
—
—
—
0
0
44
409
1.08
0.15
1.7
1.8
—
—
—
0
0
44
411
1.07
0.14
1.7
1.8
—
—
—
0
0
44
412
1.07
0.13
1.8
1.8
—
—
—
0
0
272
2664
1.03
0.13
4.4
4.5
1.75
2.23
ug/l
1.33
249
2414
14
159
0.88
0.13
1.0
1.1
0.16
2.16
u/ml
—
8
74
19
173
1.10
0.10
2.5
2.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
442.74
189.48
iu/ml
—
5
44
109
1059
1.03
0.09
1.3
1.4
—
—
—
0
0
6
70
0.86
0.07
1.2
1.3
107.23
182.99
pmol/l
—
6
70
18
167
1.08
0.07
1.3
1.2
—
—
—
0
0
32
306
1.05
0.05
1.3
1.3
—
—
—
0
0
10
110
0.91
0.05
1.7
1.5
4.99
3.95
ug/l
—
10
96
39
379
1.03
0.03
1.8
1.8
—
—
—
0
0
10
107
0.93
0.02
3.8
4.6
23.60
49.94
u/ml
—
5
33
31
318
0.97
0.02
2.0
1.7
—
—
—
0
0
51
503
1.01
0.01
1.0
1.1
—
—
—
0
0
11
112
0.98
0.00
7.7
2.3
—
—
—
0
0
18
179
1.01
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
34.27
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
15.44
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
190.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
4.5
6.5
—
—
—
0
0
6
65
0.92
-0.00
1.8
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_CHRONHEP and mortality.

Females

Parameter HR [95% CI] p-value
K11_CHRONHEP 2.604 [2.3, 2.95] < 0.001
Birth year 0.994 [0.99, 1.0] 0.142

During the follow-up period (1.1.1998 — 31.12.2019), 918 out of 3652 females with K11_CHRONHEP died.

Males

Parameter HR [95% CI] p-value
K11_CHRONHEP 3.327 [2.86, 3.87] < 0.001
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 739 out of 2256 males with K11_CHRONHEP died.

Mortality risk

Mortality risk for people of age

years, who have K11_CHRONHEP.

N-year risk Females Males
1 0.215% 0.576%
5 1.371% 4.121%
10 3.587% 9.979%
15 6.769% 19.304%
20 12.043% 30.726%

Relationships between endpoints

Index endpoint: K11_CHRONHEP – Chronic hepatitis, not elsewhere classified

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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